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https://www.readbyqxmd.com/read/29332331/egfr-mutations-and-tumor-metastases-in-patients-with-nonsmall-cell-lung-cancer-in-the-south-of-russia
#1
Oleg I Kit, Dmitry I Vodolazhsky, Natalia N Timoshkina, Lubov' Yu Vladimirova, Igor N Turkin, Ksenia A Kutsyn, Yaroslav S Enin, Svetlana B Panina, Vladimir Jurisic
PURPOSE: To assess the frequencies of somatic EGFR mutations in the tumor tissues of patients with non-small cell lung cancer (NSCLC) residing in the South of Russia (SR), and to define the relationship between genetic subtypes of NSCLC and the emergence of different types of metastases. METHODS: DNA was extracted from formalin-fixed parrafin embedded (FFPE) samples of 721 patients. A total of 29 somatic EGFR mutations were detected using commercial Therascreen EGFR RGQ PCR Kit...
November 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29332311/otolaryngology-head-and-neck-region-manifestations-of-brucella
#2
Anna Lazutkin, Maya Korem, Jeffrey M Weinberger, Ron Eliashar, Nir Hirshoren
OBJECTIVES/HYPOTHESIS: Patients with Brucella infection present with nonspecific symptoms originating from different organs. In this study, we investigated the manifestations involving principally the otolaryngology/head and neck region. STUDY DESIGN: Retrospective cohort chart review. METHODS: A retrospective analysis of patients diagnosed with brucellosis in a tertiary medical center. Medical records of 55 patients treated for positive Brucella blood cultures between 2007 and 2016 were analyzed...
January 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29332234/attitudes-of-u-s-psychiatry-residents-and-fellows-towards-mental-illness-and-its-causes-a-comparison-study-with-medical-students
#3
Catherine Chiles, Elina Stefanovics, Robert Rosenheck
Stigma towards people with mental illness remains a burden for patients and healthcare providers. This study at a large US university examined the attitudes of psychiatry residents and fellows towards mental illness and its causes, and whether their attitudes differed from the medical student attitudes previously studied utilizing the same survey method. An electronic questionnaire examining attitudes toward people with mental illness, causes of mental Illness, and treatment efficacy was used to survey the attitudes of psychiatry residents and fellows...
January 13, 2018: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29332179/profiles-and-correlates-of-parent-child-agreement-on-social-anxiety-symptoms-in-youth-with-autism-spectrum-disorder
#4
Catherine A Burrows, Lauren V Usher, Emily M Becker-Haimes, Camilla M McMahon, Peter C Mundy, Amanda Jensen-Doss, Heather A Henderson
This study characterized patterns and correlates of parent-youth agreement on social anxiety in youth with and without autism spectrum disorder (ASD). Participants (279 verbally-fluent youth aged 8-16 years, NASD = 144, NTD = 135) completed the SASC-R. Youth with ASD exhibited higher social anxiety across informants. While TD youth endorsed higher anxiety than did parents, self- and parent-reports did not differ in youth with ASD. For children with ASD, higher parent-youth agreement was associated with lower lifetime ASD symptoms and higher adaptive skills...
January 13, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29332117/pseudocholinesterase-levels-in-patients-under-electroconvulsive-therapy
#5
Gamze Küçükosman, Özcan Pişkin, Volkan Hancı, Rahşan D Okyay, Hilal Ayoğlu, Bülent S Yurtlu, Mehmet Akın, Işıl Ö Turan
In this study, we aimed to retrospectively assess the correlation of pseudocholinesterase (PChE) levels with age, gender, body weight and diagnosed psychiatric diseases in electroconvulsive therapy (ECT) cases. Methods: This retrospective study was conducted at Bülent Ecevit University Hospital, Zonguldak, Turkey, between 2007 and 2011. In the study, 193 ECT case files were retrospectively scanned to evaluate PChE values before ECT and other file information.  Results: There was no difference between gender in terms of PChE levels...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332114/dental-arch-dimensions-form-and-tooth-size-ratio-among-a-saudi-sample
#6
Haidi Omar, Manar Alhajrasi, Nayef Felemban, Ali Hassan
To determine the dental arch dimensions and arch forms in a sample of Saudi orthodontic patients, to investigate the prevalence of Bolton anterior and overall tooth size discrepancies, and to compare the effect of gender on the measured parameters. Methods: This study is a biometric analysis of dental casts of 149 young adults recruited from different orthodontic centers in Jeddah, Saudi Arabia. The dental arch dimensions were measured. The measured parameters were arch length, arch width, Bolton's ratio, and arch form...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332108/impact-of-body-mass-index-on-high-blood-pressure-among-obese-children-in-the-western-region-of-saudi-arabia
#7
Abdulmoein E Al-Agha, Areej O Mahjoub
To evaluate the impact of body mass index (BMI) on high blood pressure among obese children and adolescents in western region, Saudi Arabia.  Methods: Cross-sectional data were obtained from 306 (female: 140, male: 166) child, between August 2016 and March 2017. A questioner was filled by health professionals at ambulatory pediatric clinic followed by waist-hip circumference, height, weight, and blood pressure measurement. Diastolic blood pressure (DBP) and systolic blood pressure (SBP) were adjusted to gender, height, and age...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332000/how-good-are-doctors-at-introducing-themselves-hellomynameis
#8
Peter Gillen, Sue Faye Sharifuddin, Muireann O'Sullivan, Alison Gordon, Eva M Doherty
BACKGROUND: This explorative study was triggered by the '#hellomynameis' campaign initiated by Dr Kate Granger in the UK. Our objectives were twofold: first, to measure rates of introduction in an Irish hospital setting by both consultant and non-consultant hospital doctors. Second to establish whether such practices were associated with patient perceptions of the doctor/patient interaction. METHOD: A patient 'exit' survey was undertaken following doctor-patient consultations in both acute (surgical and medical assessment units) and elective settings (outpatient clinics)...
January 13, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29331986/sex-differences-in-impact-of-coronary-artery-calcification-to-predict-coronary-artery-disease
#9
Yoko M Nakao, Yoshihiro Miyamoto, Masahiro Higashi, Teruo Noguchi, Mitsuru Ohishi, Isao Kubota, Hiroyuki Tsutsui, Tomohiro Kawasaki, Yutaka Furukawa, Michihiro Yoshimura, Hideaki Morita, Kunihiro Nishimura, Akiko Kada, Yoichi Goto, Tomonori Okamura, Chuwa Tei, Hitonobu Tomoike, Hiroaki Naito, Satoshi Yasuda
OBJECTIVE: To assess sex-specific differences regarding use of conventional risks and coronary artery calcification (CAC) to detect coronary artery disease (CAD) using coronary CT angiography (CCTA). METHODS: The Nationwide Gender-specific Atherosclerosis Determinants Estimation and Ischemic Cardiovascular Disease Prospective Cohort study is a prospective, multicentre, nationwide cohort study. Candidates with suspected CAD aged 50-74 years enrolled from 2008 to 2012...
January 13, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29331875/the-association-between-vitamin-d-receptor-polymorphisms-and-multiple-sclerosis-in-a-turkish-population
#10
Ozden Kamisli, Ceren Acar, Mert Sozen, Mehmet Tecellioglu, Fatma Ebru Yücel, Dilara Vaizoglu, Cemal Özcan
BACKGROUND: Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system (CNS). Genetic and environmental factors are important in disease development. Many studies have investigated the relationship between MS and VDR polymorphisms. VDR gene polymorphism has not been previously studied in Turkish MS patients. We aimed to investigate the relationship between MS and VDR genotypes Taq I, Apa I and Fok I polymorphisms in a Turkish population. METHODS: 167 MS patients and 146 healthy control subjects were included in the present study...
January 9, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29331731/deoxynivalenol-gut-microbiota-and-immunotoxicity-a-potential-approach
#11
REVIEW
Yuxiao Liao, Zhao Peng, Liangkai Chen, Andreas K Nüssler, Liegang Liu, Wei Yang
Deoxynivalenol (DON, vomitoxin) is the most frequent mycotoxin in grains and grain products. DON contamination in fodder and food is a serious threat for health, since it impairs the immune and gastrointestinal systems of both human and animals. Gut microbiota seems to play a more and more important part in human and animals' health according to related researches. Previous studies implied some associations among gut microbiota, DON and immune system. For example, DON affects immune system as well as the composition and abundance of gut microbiota, and the latter influences immune system as well...
January 10, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29331704/mindfulness-based-interventions-for-major-depressive-disorder-a-comprehensive-meta-analysis-of-randomized-controlled-trials
#12
Yuan-Yuan Wang, Xiao-Hong Li, Wei Zheng, Zi-Yan Xu, Chee H Ng, Gabor S Ungvari, Zhen Yuan, Yu-Tao Xiang
BACKGROUND: This is a meta-analysis of randomized controlled trials (RCTs) of mindfulness-based interventions (MBIs) for a current episode of major depressive disorder. METHODS: Both English (PubMed, PsycINFO, Embase, and Cochrane Library databases) and Chinese (WanFang and CNKI) databases were systematically and independently searched. Standardized mean differences (SMDs) and risk ratio (RR) ± their 95% confidence intervals (CIs) based on the random effects model were calculated...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29331440/the-effect-of-bilateral-eye-movements-versus-no-eye-movements-on-sexual-fantasies
#13
Ross M Bartels, Leigh Harkins, Samantha C Harrison, Nikki Beard, Anthony R Beech
BACKGROUND AND OBJECTIVES: Bilateral eye-movements (EMs) and visual mental imagery both require working memory resources. When performed together, they compete for these resources, which can cause various forms of mental imagery to become impaired (e.g., less vivid). This study aimed to examine whether EMs impair sexual fantasies (a form of mental imagery) in the same manner. METHODS: Eighty undergraduates (40 males, 40 females) took part in four counterbalanced conditions: (1) EMs and an experience-based sexual fantasy; (2) EMs and an imagination-based sexual fantasy; (3) experience-based sexual fantasy only; and (4) imagination-based sexual fantasy only...
January 4, 2018: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/29331304/gender-representation-in-urological-subspecialties
#14
Oluwarotimi S Nettey, Joceline S Fuchs, Stephanie J Kielb, Edward M Schaeffer
OBJECTIVE: To examine associations between urologic subspecialization, surgeon gender and practice patterns among certifying urologists over the last 13 years. MATERIALS AND METHODS: Demographic data of certifying and recertifying urologists (2004 to 2015) was obtained from the American Board of Urology (ABU). We investigated gender-specific trends in self-reported practice type (academic practice, private practice), subspecialization, and employment as a full-time versus part-time physician, relative to certification year and cycle...
January 10, 2018: Urology
https://www.readbyqxmd.com/read/29331274/clinical-outcomes-of-endoscopic-submucosal-dissection-for-large-colorectal-laterally-spreading-tumors-in-older-adults
#15
Jing Jing Lian, Li Li Ma, Yi Qun Zhang, Wei Feng Chen, Yun Shi Zhong, Mei Dong Xu, Ping Hong Zhou, Shi Yao Chen
BACKGROUND AND AIMS: The colorectal endoscopic submucosal dissection (ESD) remains technically challenging, especially for older patients who frequently encounter complex chronic diseases and have a loose colon. However, only limited number of studies are available for the safety of ESD in older patients with especially large laterally spreading tumors. Therefore, in this retrospective study, we compared the outcomes of ESD for laterally spreading tumors (LST) ≥3cm(cm) in older patients to that in younger patients...
January 10, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29331048/dog-bites-in-a-us-county-age-body-part-and-breed-in-pediatric-dog-bites
#16
Sriram Ramgopal, Lauren Bealafeld Brungo, Michael Bykowski, Raymond Pitetti, Robert Hickey
AIM: To compare characteristics of gender, age, body part, and breed in dog bites. METHODS: We reviewed 14,956 dog bites (4,195 pediatric) reported to the Allegehny County Health Department, USA, between 2007-2015. Using pre-defined age groups, we performed linear regression to assess for subject age and bite frequency and used binary logistic regression to evaluate for differences in gender and body part and chi-squared tests with Bonferroni correction to evaluate for differences in reported breeds with age...
January 13, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29330985/medical-students-perceptions-of-their-learning-environment-at-lahore-medical-and-dental-college-lahore
#17
Uzma Zafar, Seema Daud, Qamar Shakoor, Abdul Majeed Chaudhry, Fahad Naser, Mehreen Mushtaq
BACKGROUND: The present study was designed to assess medical students' perceptions of their learning environment at Lahore Medical and Dental College, Lahore. METHODS: It was a crosssectional descriptive study conducted at Lahore Medical and Dental College, Lahore. Five hundred and thirty-three students participated in this study. A questionnaire was used as a study tool, comprising of demographic information and the 'Dundee Ready Education Environment Measure' (DREEM) inventory...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29330975/emergency-inguinal-hernia-repair-comparison-of-desarda-s-versus-darning-technique
#18
Adeel Hussain, Syed Mehsam, Mansab Ali, Shahid Rasul, Sughra Parveen, Ahson Memon
BACKGROUND: Emergency inguinal hernia repair remains the commonest operation performed by general surgeons all over the world. The aim of this study was to compare the mean operative time, post-operative pain, wound infection and early recurrence between Desarda's and Darning emergency inguinal hernia repair. METHODS: This is a randomized controlled trial conducted at Jinnah Postgraduate Medical Centre, Karachi. A total of 186 patients of male gender between ages 20-60 years with incarcerated, obstructed and strangulated inguinal hernia were enrolled in the study...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29330930/gender-specific-risk-factors-for-androgenetic-alopecia-in-the-korean-general-population-associations-with-medical-comorbidities-and-general-health-behaviors
#19
Bo-Kyung Kim, Sung Jay Choe, Hee-Chul Chung, Sung-Soo Oh, Won-Soo Lee
BACKGROUND: The relationships between androgenetic alopecia (AGA) and various factors related to metabolic syndrome have been demonstrated in previous studies. However, it remains unclear because of inconsistent results. We investigated the associations between AGA and various risk factors related to metabolic syndrome according to gender. METHODS: We conducted a population-based cross-sectional survey of 2028 Koreans (1050 men, 978 women). The basic and specific (BASP) classification was used for diagnosis of AGA...
February 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#20
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
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