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https://www.readbyqxmd.com/read/29150898/a-model-to-characterize-psychopathological-features-in-adults-with-prader-willi-syndrome
#1
Denise Thuilleaux, Virginie Laurier, Pierre Copet, Julie Tricot, Geneviève Demeer, Fabien Mourre, Maithé Tauber, Joseba Jauregi
High prevalence of behavioral and psychiatric disorders in adults with Prader-Willi Syndrome (PWS) has been reported in last few years. However, data are confusing and often contradictory. In this article, we propose a model to achieve a better understanding of the psychopathological features in adults with PWS. The study is based on clinical observations of 150 adult inpatients, males and females. Non-parametric statistics were performed to analyse the association of psychopathological profiles with genotype, gender and age...
November 17, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29150840/longitudinal-pathways-between-mental-health-difficulties-and-academic-performance-during-middle-childhood-and-early-adolescence
#2
Jessica Deighton, Neil Humphrey, Jay Belsky, Jan Boehnke, Panos Vostanis, Praveetha Patalay
There is a growing appreciation that child functioning in different domains, levels, or systems are interrelated over time. Here, we investigate links between internalizing symptoms, externalizing problems, and academic attainment during middle childhood and early adolescence, drawing on two large data sets (child: mean age 8.7 at enrolment, n = 5,878; adolescent: mean age 11.7, n = 6,388). Using a 2-year cross-lag design, we test three hypotheses - adjustment erosion, academic incompetence, and shared risk - while also examining the moderating influence of gender...
November 18, 2017: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/29150796/gender-differences-in-chronic-liver-diseases-in-two-cohorts-of-2001-and-2014-in-italy
#3
Evangelista Sagnelli, Tommaso Stroffolini, Caterina Sagnelli, Mario Pirisi, Sergio Babudieri, Guido Colloredo, Maurizio Russello, Nicola Coppola, Giovanni Battista Gaeta, Bruno Cacopardo, Massimo De Luca, Piero Luigi Almasio
BACKGROUND: Gender differences in chronic liver disease (CLD) have been partially investigated. To extend the present knowledge, we evaluated 12,263 patients with CLD enrolled in two national surveys (9997 in 2001 and 2557 in 2014). METHODS: The two surveys prospectively recruited patients aged ≥ 18 referring to Italian liver units throughout the country using a similar clinical approach and analytical methods. RESULTS: The overall male to female ratio (M/F) was 1...
November 17, 2017: Infection
https://www.readbyqxmd.com/read/29150747/for-whom-do-parenting-interventions-to-prevent-adolescent-substance-use-work
#4
REVIEW
Diego Garcia-Huidobro, Jennifer L Doty, Laurel Davis, Iris W Borowsky, Michele L Allen
Adolescent substance use continues to be a significant public health problem. Parent training interventions are effective preventive strategies to reduce youth substance use. However, little is known about differences in effectiveness for youth across demographic characteristics. This review assessed the effectiveness of parent training programs at reducing adolescent substance use by participant gender, age, and race/ethnicity. Pubmed/MEDLINE, ERIC, CINAHL, and PsycINFO were searched from database origin to October 31, 2016...
November 18, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29150473/patient-level-and-practice-level-factors-associated-with-consultation-duration-a-cross-sectional-analysis-of-over-one-million-consultations-in-english-primary-care
#5
Sarah Stevens, Clare Bankhead, Toqir Mukhtar, Rafael Perera-Salazar, Tim A Holt, Chris Salisbury, F D Richard Hobbs
OBJECTIVES: Consultation duration has previously been shown to be associated with patient, practitioner and practice characteristics. However, previous studies were conducted outside the UK, considered only small numbers of general practitioner (GP) consultations or focused primarily on practitioner-level characteristics. We aimed to determine the patient-level and practice-level factors associated with duration of GP and nurse consultations in UK primary care. DESIGN AND SETTING: Cross-sectional data were obtained from English general practices contributing to the Clinical Practice Research Datalink (CPRD) linked to data on patient deprivation and practice staffing, rurality and Quality and Outcomes Framework (QOF) achievement...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29150298/spontaneous-osteoclastogenesis-hypothesis-for-gender-unrelated-osteoporosis-screening-and-diagnosis
#6
F Salamanna, R Giardino, M Fini
Women are at greater risk of developing osteoporosis (OP). However, in the past few years it has become more widely recognized that OP is a significant problem also in men although OP is frequently under-diagnosed and, consequently, under treated in men. Most guidelines, screening and fracture risk evaluation methods as well as pharmacologic agents have been developed for women and then adapted to men. Bone Mineral Density (BMD) measurement by Dual X-ray Absorptiometry (DEXA) is reported as T score and the capability of DEXA to diagnose OP and predict fracture risk is still debated...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29150193/descriptive-epidemiology-of-traumatic-spinal-injury-in-japan
#7
Mahammad Abbas Tafida, Yukiko Wagatsuma, Enbo Ma, Taro Mizutani, Toshikazu Abe
BACKGROUND: Spine injury epidemiology in Japan has not been studied since the 1990s when its incidence was 39.4-40.2 per million and the major cause of injury was motor vehicle crashes. We elucidate the current epidemiological state of spinal injury and spinal injury patients in Japan for the clinicians and public health prevention programs. METHODS: Spine injury patients were retrospectively selected from the Japan Trauma Data Bank (JTDB) from 2004 to 2013 for all ages and all spinal injuries...
November 14, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29150101/lack-of-association-between-kidd-blood-group-system-and-chronic-kidney-disease
#8
Tiago Verri Capriolli, Jeane Eliete Laguila Visentainer, Ana Maria Sell
BACKGROUND: The Kidd blood group system has three antigens, Jk(a), Jk(b) and Jk3, found on red blood cells and on endothelial cells of the inner lining of blood vessels in the renal medulla. These are known as urea transporter B (UT-B). Researchers have found that individuals carrying the Jk(a-b-) or Jk-null (UT-B null) phenotypes have a lower urine-concentrating capability and risk of severe renal impairment. This study evaluated the distribution of the Kidd phenotypes in patients with chronic kidney disease and a possible association of Kidd antigens with the development of renal disease...
October 2017: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/29149937/personalizing-sepsis-care
#9
REVIEW
Mervyn Singer
Sepsis describes a broad-based syndrome covering many infectious agents, affecting various sites in patients of differing age, gender, and comorbidity and resulting in varying degrees and combinations of organ dysfunction. Protocolized care with rigid goals may suit populations, assuming the evidence-lite recommendations are beneficial, but not necessarily individual patients. A personalized approach to management is rational and preferable. Other than clinical heterogeneity, a range of biological signatures exist in sepsis, and these fluctuate over the disease course...
January 2018: Critical Care Clinics
https://www.readbyqxmd.com/read/29149871/near-work-outdoor-activity-and-myopia-in-children-in-rural-china-the-handan-offspring-myopia-study
#10
Zhong Lin, Tie Ying Gao, Balamurali Vasudevan, Kenneth J Ciuffreda, Yuan Bo Liang, Vishal Jhanji, Su Jie Fan, Wei Han, Ning Li Wang
BACKGROUND: The near work and outdoor activity are the most important environmental risk factors for myopia. However, data from Chinese rural children are relatively rare and remain controversial. Therefore, the purpose of this study was to evaluate the relationship of both near work and outdoor activities with refractive error in rural children in China. METHODS: In this cross-sectional study, 572 (65.1%) of 878 children (6-18 years of age) were included from the Handan Offspring Myopia Study (HOMS)...
November 17, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29149219/characterization-and-classification-of-lupus-patients-based-on-plasma-thermograms
#11
Nichola C Garbett, Guy N Brock, Jonathan B Chaires, Chongkham S Mekmaysy, Lynn DeLeeuw, Kathy L Sivils, John B Harley, Brad H Rovin, K B Kulasekera, Wael N Jarjour
OBJECTIVE: Plasma thermograms (thermal stability profiles of blood plasma) are being utilized as a new diagnostic approach for clinical assessment. In this study, we investigated the ability of plasma thermograms to classify systemic lupus erythematosus (SLE) patients versus non SLE controls using a sample of 300 SLE and 300 control subjects from the Lupus Family Registry and Repository. Additionally, we evaluated the heterogeneity of thermograms along age, sex, ethnicity, concurrent health conditions and SLE diagnostic criteria...
2017: PloS One
https://www.readbyqxmd.com/read/29149151/sacroplasty-a-ten-year-analysis-of-prospective-patients-treated-with-percutaneous-sacroplasty-literature-review-and-technical-considerations
#12
Michael E Frey, Christopher Warner, Samuel M Thomas, Karan Johar, Heathpaul Singh, Maheen S Mohammad, Douglas P Beall
BACKGROUND: The treatment of sacral fractures has evolved since its first description in 1982. Several techniques for sacral augmentation have been developed since 2001, and the rate of improvement is rapid with over 50% reduction in pain achieved prior to post-procedure discharge of the patient. Pain reduction occurs primarily within the first 3 months and is sustained at 12 months; however, the long-term outcomes have not previously been studied. OBJECTIVES: We aim to evaluate the long-term efficacy of sacroplasty versus non-surgical management (NSM) in treating sacral insufficiency fractures (SIFs), including the effect on pain relief, opioid and other analgesic use, patient satisfaction, and complication rates...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29149142/mapping-the-association-between-vitamin-d-and-low-back-pain-a-systematic-review-and-meta-analysis-of-observational-studies
#13
Joshua Zadro, Debra Shirley, Manuela Ferreira, Ana Paula Carvalho-Silva, Sarah E Lamb, Cyrus Cooper, Paulo H Ferreira
BACKGROUND: Low back pain (LBP) is the highest contributor to disability worldwide, with current intervention strategies only providing small to moderate analgesic effects. The use of vitamin D supplementation for LBP has gained interest due to its proposed anti-inflammatory and neuromodulatory properties. However, it is still unclear whether vitamin D levels differ between those with and without LBP or if vitamin D levels are associated with pain intensity. OBJECTIVES: We aim to investigate the association between vitamin D levels and LBP and to determine if vitamin D levels correlate with pain intensity in individuals with LBP...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29149021/using-gamma-and-quantile-regressions-to-explore-the-association-between-job-strain-and-adiposity-in-the-elsa-brasil-study-does-gender-matter
#14
Maria de Jesus Mendes da Fonseca, Leidjaira Lopes Juvanhol, Lúcia Rotenberg, Aline Araújo Nobre, Rosane Härter Griep, Márcia Guimarães de Mello Alves, Letícia de Oliveira Cardoso, Luana Giatti, Maria Angélica Nunes, Estela M L Aquino, Dóra Chor
This paper explores the association between job strain and adiposity, using two statistical analysis approaches and considering the role of gender. The research evaluated 11,960 active baseline participants (2008-2010) in the ELSA-Brasil study. Job strain was evaluated through a demand-control questionnaire, while body mass index (BMI) and waist circumference (WC) were evaluated in continuous form. The associations were estimated using gamma regression models with an identity link function. Quantile regression models were also estimated from the final set of co-variables established by gamma regression...
November 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29148066/predicting-the-use-of-corporal-punishment-child-aggression-parent-religiosity-and-the-bdnf-gene
#15
Reut Avinun, Maayan Davidov, David Mankuta, Ariel Knafo-Noam
Corporal punishment (CP) has been associated with deleterious child outcomes, highlighting the importance of understanding its underpinnings. Although several factors have been linked with parents' CP use, genetic influences on CP have rarely been studied, and an integrative view examining the interplay between different predictors of CP is missing. We focused on the separate and joint effects of religiosity, child aggression, parent's gender, and a valine (Val) to methionine (Met) substitution in the brain-derived neurotrophic factor (BDNF) gene...
November 17, 2017: Aggressive Behavior
https://www.readbyqxmd.com/read/29148004/cephalad-dislocation-of-piccs-under-different-upper-limb-positions-influence-of-age-gender-bmi-number-of-lumens
#16
Chie-Hee Cho, Peter Schlattmann, Sebastian Nagel, Nina Schmittbuttner, Frederic Hartung, Ulf K Teichgraber
PURPOSE: To evaluate parameters that influence the amount of movement of peripherally inserted central catheter (PICC) tips regarding upper limb movement. METHODS: In a prospective 12-month observational study, 200 PICCs were implanted in 162 patients (mean age 56.8 ± 15.2 years) by interventional radiologists into the basilic vein of the mid-aspect of the upper arm. Three PICC tip positions were documented with a chest x-ray: patient supine with an abducted (90°), an adducted arm, and in an upright position with an adducted arm...
November 9, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/29147953/impact-of-perfluorochemicals-on-human-health-and-reproduction-a-male-s-perspective
#17
REVIEW
C Foresta, S Tescari, A Di Nisio
Perfluoroalkyl compounds (PFCs) are a class of organic molecules used in industry and consumer products. PFCs are non-biodegradable and bioaccumulate in the environment and for these reasons they have been a major subject of research regarding their toxicity, environmental fate, and sources of human exposure, since they have been shown to induce severe health consequences, such as neonatal mortality, neurotoxicity and immunotoxicity. The aim of this review is to explore the existing knowledge of the interplay between PFCs exposure and human health, with a focus on male reproductive health, given the emerging gender differences in PFCs clearance and their interaction with sex hormones receptors...
November 17, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29147888/a-study-of-parental-presence-absence-technique-for-child-dental-behaviour-management
#18
V Boka, K Arapostathis, G Charitoudis, J Veerkamp, C van Loveren, N Kotsanos
AIM: To examine the effectiveness of parental presence/absence (PPA) technique on the dental behaviour management of children. MATERIALS AND METHODS: This randomised control study recruited 61 child dental patients with uncooperative behaviour (Frankl 1 or 2) managed with AAPD-endorsed non-pharmacological techniques at a post-graduate university clinic. PPA was only used in the test group (31 children). Using a mini video-tape device, recording commenced at the onset of uncooperative behaviour and this was later rated, minute by minute, by a blinded experienced paediatric dentist...
November 16, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29147664/reduced-inspiratory-muscle-strength-in-patients-with-type-2-diabetes-mellitus-and-obstructive-sleep-apnoea
#19
Thomas Rehling, Anne Margareta Banghøj, Marie Hvelplund Kristiansen, Lise Tarnow, Stig Molsted
Background: Obstructive sleep apnoea (OSA) is related to type 2 diabetes (T2DM), and it may be associated with reduced inspiratory muscle strength (IMS). The aim of this study was to investigate the IMS in patients with T2DM, with or without OSA. Methods: Patients with T2DM with OSA (n = 33) and without OSA (n = 28) were included. The maximum IMS was tested using the POWERbreathe KH2 device. Reference IMS values were data calculated using an algorithm based on general populations and adjusted for age and gender...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29147631/automated-whole-brain-tractography-affects-preoperative-surgical-decision-making
#20
Hesham Zakaria, Sameah Haider, Ian Lee
Surgery in and around eloquent brain structures poses a technical challenge when the goal of surgery is maximal safe resection. Magnetic resonance imaging (MRI) has revolutionized the diagnosis and treatment of neurological disorders, but tractography still remains limited in terms of utility because of the requisite manual labor and time required combined with the high risk of bias and inaccuracy. Automated whole brain tractography (AWBT) has simplified this workflow, overcoming historical barriers, and allowing for integration into modern neuronavigation...
September 6, 2017: Curēus
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