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https://www.readbyqxmd.com/read/29157850/conventional-computed-tomography-and-magnetic-resonance-in-brain-concussion
#1
REVIEW
Juan Nicolas Useche, Sonia Bermudez
Conventional neuroimaging is still the mainstay in the assessment of the acute, follow-up, and chronic settings of concussion and mild traumatic brain injury (mTBI). Computed tomography (CT) is preferred for the initial assessment of acute mTBI, repeat evaluation in acute mTBI with neurologic deterioration, and cautious use in children with mTBI. Clinical rules have been developed to identify pediatric and adult patients with mTBI who can safely forego CT. Magnetic resonance (MR) imaging is mostly used in patients with acute mTBI when initial or follow-up CT is normal and there are persistent neurologic findings and in subacute or chronic mTBI...
February 2018: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/29153996/clinical-presentation-of-anti-n-methyl-d-aspartate-receptor-and-anti-voltage-gated-potassium-channel-complex-antibodies-in-children-a-series-of-24-cases
#2
Bahadir Konuskan, Mirac Yildirim, Haluk Topaloglu, Ilknur Erol, Ulkuhan Oztoprak, Huseyin Tan, Rahsan Gocmen, Banu Anlar
OBJECTIVE: The symptomatology and paraclinical findings of antibody-mediated encephalitis, a relatively novel disorder, are still being characterized in adults and children. A high index of suspicion is needed in order to identify these cases among children presenting with various neurological symptoms. The aim of this study is to examine the clinical, demographic and laboratory findings and outcome of children with anti-NMDAR and anti-VGKC encephalitis for any typical or distinctive features...
November 7, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29153727/lifetime-exposure-to-particulate-air-pollutants-is-negatively-associated-with-lung-function-in-non-asthmatic-children
#3
Hung-Chang Tsui, Chi-Hsien Chen, Ying-Hsuan Wu, Hung-Che Chiang, Bing-Yu Chen, Yue Leon Guo
BACKGROUND: Pulmonary function is known to be affected by acute and subacute exposure to ambient air pollution. However, the impacts of lifetime exposure to air pollution on the pulmonary function of children have been inconsistent. The present study investigated the impact of lifetime residential exposure to intermediate levels of air pollution on the pulmonary function of schoolchildren. METHODS: In 2011, a survey of children aged 6-15 years was conducted in 44 schools in Taiwan...
November 16, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29153519/invited-review-practical-feeding-management-recommendations-to-mitigate-the-risk-of-subacute-ruminal-acidosis-in-dairy-cattle
#4
E Humer, R M Petri, J R Aschenbach, B J Bradford, G B Penner, M Tafaj, K-H Südekum, Q Zebeli
Rumen health is of vital importance in ensuring healthy and efficient dairy cattle production. Current feeding programs for cattle recommend concentrate-rich diets to meet the high nutritional needs of cows during lactation and enhance cost-efficiency. These diets, however, can impair rumen health. The term "subacute ruminal acidosis" (SARA) is often used as a synonym for poor rumen health. In this review, we first describe the physiological demands of cattle for dietary physically effective fiber. We also provide background information on the importance of enhancing salivary secretions and short-chain fatty acid absorption across the stratified squamous epithelium of the rumen; thus, preventing the disruption of the ruminal acid-base balance, a process that paves the way for acidification of the rumen...
November 15, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29153518/subacute-ruminal-acidosis-affects-fermentation-and-endotoxin-concentration-in-the-rumen-and-relative-expression-of-the-cd14-tlr4-md2-genes-involved-in-lipopolysaccharide-systemic-immune-response-in-dairy-cows
#5
B Stefanska, W Człapa, E Pruszynska-Oszmałek, D Szczepankiewicz, V Fievez, J Komisarek, K Stajek, W Nowak
The first objective of this study was to investigate the effects of subacute ruminal acidosis (SARA) on fermentation, ruminal free lipopolysaccharides (LPS), and expression of the cluster of differentiation 14 (CD14), toll-like receptor 4 (TLR4), and myeloid differentiation protein 2 (MD2) complex in white blood cells involved in the systemic immune response in dairy cows. The second objective was a study of whether increased expression of the LPS receptor complex led to increases in the concentrations of plasma high-density lipoprotein (HDL) and serum Ca...
November 15, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29153271/subacute-corticobasal-syndrome-following-internal-carotid-endarterectomy
#6
A Marques, N Bourgois, T Vidal, A Ferrier, S Mathais, C Merlin, C Valla, E De Schlichting, B Jean, D Deffond, F Durif
The present report is of two patients who, immediately after internal carotid endarterectomy, presented with unexplained hemiplegia, despite normal findings on repeated MRI scans, which secondarily evolved into homolateral subacute corticobasal syndrome (CBS), with asymmetrical hemispheric hypometabolism and evidence of dopaminergic denervation. This prompted us to propose an hypothesis of transient cerebral hypoxia arising during the surgical clamping period that might have provoked a prolonged or permanent functional lesion of the left hemisphere and basal ganglia, with no visible infarction on MRI but only synaptic rearrangement of the neural networks, thereby revealing or exacerbating a potentially preexisting silent impairment...
November 15, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/29147661/an-eeg-tool-for-monitoring-patient-engagement-during-stroke-rehabilitation-a-feasibility-study
#7
Gadi Bartur, Katherin Joubran, Sara Peleg-Shani, Jean-Jacques Vatine, Goded Shahaf
Objective: Patient engagement is of major significance in neural rehabilitation. We developed a real-time EEG marker for attention, the Brain Engagement Index (BEI). In this work we investigate the relation between the BEI and temporary functional change during a rehabilitation session. Methods: First part: 13 unimpaired controls underwent BEI monitoring during motor exercise of varying levels of difficulty. Second part: 18 subacute stroke patients underwent standard motor rehabilitation with and without use of real-time BEI feedback regarding their level of engagement...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29145816/renal-failure-during-chemotherapy-renal-biopsy-for-assessing-subacute-nephrotoxicity-of-pemetrexed
#8
Maureen Assayag, Philippe Rouvier, Marion Gauthier, Ghania Costel, Philippe Cluzel, Lucile Mercadal, Gilbert Deray, Corinne Isnard Bagnis
BACKGROUND: Pemetrexed, a multitargeted antifolate cytotoxic agent, is currently used primarily in combination with cisplatin for metastatic non-small cell lung cancer and for malignant mesothelioma. Acute renal toxicity of pemetrexed has been recently described with polychemotherapy, in which the individual responsibility of each drug is difficult to establish. Only one recent report documents renal involvement in long-term exposed patients. CASE PRESENTATION: We report on a case of rapidly progressive nephropathy leading to the cessation of platinum salts and the secondary interruption of pemetrexed and bevacizumab...
November 16, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29145323/the-effectiveness-of-2-consecutive-intra-articular-polydeoxyribonucleotide-injections-compared-with-intra-articular-triamcinolone-for-hemiplegic-shoulder-pain-a-strobe-complaint-retrospective-study
#9
Donghwi Park, Kwang Jae Yu, Ju Young Cho, Seung Beom Woo, Junu Park, Zeeihn Lee, Jong Min Kim
The aim of this study was to investigate the effects of intra-articular injection of polydeoxyribonucleotide (PDRN), compared with intraarticular triamcinolone (TA) injection, in subacute stroke patients with hemiplegic shoulder pain (HSP).Participants were subacute stroke patients with HSP who had undergone 2 consecutive intra-articular injections of TA or PDRN.Numeric rating scale (NRS) and passive range of motion (PROM) of hemiplegic shoulder were evaluated until 4 weeks after 2nd injection.In the results, there were significant improvements in all PROM measures 2 weeks after the second injection, compared with pre-injection results, in both groups (P < ...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145108/acute-calcific-tendinitis-of-the-longus-colli-muscle-masquerading-as-a-retropharyngeal-abscess-a-case-report-and-review-of-the-literature
#10
Uthman Alamoudi, Ahmed A Al-Sayed, Yasser AlSallumi, Matthew H Rigby, S Mark Taylor, Robert D Hart, Jonathan R B Trites
INTRODUCTION: Acute calcific longus colli tendinitis, also known as retropharyngeal or acute calcific prevertebral tendinitis, is a reactive self-limiting inflammatory response to acute or subacute deposition of amorphous calcium hydroxyapatite crystals in the tendons of the longus colli muscle, anterior to the C1-C2 disk space. CASE PRESENTATION: A 53-year-old man presented with a complaint of neck pain and odynophagia over a few days. Blood test findings showed mild leukocytosis and elevated C-reactive protein level...
November 11, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29143126/-spinal-orthoses-in-the-treatment-of-vertebral-fractures-with-osteoporosis-a-systematic-review-article
#11
REVIEW
M Pfeifer, M Gehlen, C Hinz
This literature search concerning the potential role of spinal orthoses for rehabilitation and treatment of atraumatic vertebral fractures between Th4 and L5 with osteoporosis and without any evidence for a secondary cause, provided no evidence for the benefits of traditional rigid thoracolumbar corsets, which only had a poor compliance. In addition, there are indications that these rigid corsets may even worsen the disease condition especially in the long-term. Wearing these corsets can result in further loss of muscle mass and strength followed by loss of bone and bone mass...
November 15, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29142090/virtual-reality-training-for-upper-extremity-in-subacute-stroke-virtues-a-multicenter-rct
#12
Iris Brunner, Jan Sture Skouen, Håkon Hofstad, Jörg Aßmus, Frank Becker, Anne-Marthe Sanders, Hanne Pallesen, Lola Qvist Kristensen, Marc Michielsen, Liselot Thijs, Geert Verheyden
OBJECTIVE: To compare the effectiveness of upper extremity virtual reality rehabilitation training (VR) to time-matched conventional training (CT) in the subacute phase after stroke. METHODS: In this randomized, controlled, single-blind phase III multicenter trial, 120 participants with upper extremity motor impairment within 12 weeks after stroke were consecutively included at 5 rehabilitation institutions. Participants were randomized to either VR or CT as an adjunct to standard rehabilitation and stratified according to mild to moderate or severe hand paresis, defined as ≥20 degrees wrist and 10 degrees finger extension or less, respectively...
November 15, 2017: Neurology
https://www.readbyqxmd.com/read/29141924/antenatal-bartter-syndrome-presenting-with-vomiting-and-constipation-mimicking-subacute-intestinal-obstruction-in-a-20-day-old-neonate
#13
Ibtihal Siddiq Abdelgadir, Fawzia Elgharbawy, Khalil Mohamad Salameh, Baha Eldin Juma
Antenatal Bartter syndrome is a rare condition that can present with different clinical features. These features include early onset maternal polyhydramnios, failure to thrive, prematurity and nephrocalcinosis.We are presenting this 20-day-old girl who had an antenatal history of polyhydramnios. She developed persistent non-bilious vomiting that was associated with constipation soon after birth. She presented with failure to thrive and features suggestive of intestinal obstruction. On the initial evaluation, she was noted to have hypokalaemic, hyponatraemic metabolic alkalosis...
November 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29141478/utility-of-quick-oculomotor-tests-for-screening-the-vestibular-system-in-the-subacute-and-chronic-populations
#14
Helen S Cohen, Jasmine Stitz, Haleh Sangi-Haghpeykar, Susan P Williams, Ajitkumar P Mulavara, Brian T Peters, Jacob J Bloomberg
OBJECTIVE: The goal of this study was to determine the sensitivity and specificity of some widely used, easily administered clinical tests. BACKGROUND: Simple tests of oculomotor function have become widely used for clinical screening of patients suspected of having vestibular disorders despite a paucity of evidence showing good statistical support for their use in this highly variable population. METHODS: Healthy controls with no history of otologic or neurologic disorders (n = 291) were compared to patients with known vestibular disorders (n = 62)...
November 16, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29140826/effects-of-integrating-rhythmic-arm-swing-into-robot-assisted-walking-in-patients-with-subacute-stroke-a-randomized-controlled-pilot-study
#15
Tae-Woo Kang, Duck-Won Oh, Ji-Hyun Lee, Heon-Seock Cynn
This study aimed to identify the effects of rhythmic arm swing during robot-assisted walking training on balance, gait, motor function, and activities of daily living among patients with subacute stroke. Twenty patients with subacute stroke were recruited, and thereafter randomly allocated to either the experimental group that performed the robot-assisted walking training with rhythmic arm swing, or the control group that performed the training in arm fixation. In total, 30 training sessions were carried out...
November 14, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/29139241/porcine-respiratory-disease-complex-after-the-introduction-of-h1n1-2009-influenza-virus-in-brazil
#16
R R Rech, D Gava, M C Silva, L T Fernandes, V Haach, J R Ciacci-Zanella, R Schaefer
From 2009 to 2015, 74 lungs from suckling (6.8%), nursing (70.3%), fattening (20.3%) pigs and pregnant sows (2.7%) with respiratory signs from pig farms in Southern Brazil were submitted to a diagnostic laboratory for necropsy and/or histologic examination and screening for respiratory agents by RT-qPCR, immunohistochemistry (IHC), virus isolation (VI) and subtyping for influenza A virus (IAV), IHC and nested PCR for Mycoplasma hyopneumoniae (Mhyo), PCR for porcine circovirus 2 (PCV2), RT-qPCR for porcine reproductive and respiratory syndrome virus (PRRSV) and bacterial culture...
November 14, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29138115/active-forms-of-akt-and-erk-are-dominant-in-the-cerebral-cortex-of-newborn-pigs-that-are-unaffected-by-asphyxia
#17
Viktória Kovács, Valéria Tóth-Szűki, János Németh, Viktória Varga, Gábor Remzső, Ferenc Domoki
AIMS: Perinatal asphyxia (PA) often results in hypoxic-ischemic encephalopathy (HIE) in term neonates. Introduction of therapeutic hypothermia improved HIE outcome, but further neuroprotective therapies are still warranted. The present study sought to determine the feasibility of the activation of the cytoprotective PI-3-K/Akt and the MAPK/ERK signaling pathways in the subacute phase of HIE development in a translational newborn pig PA/HIE model. MAIN METHODS: Phosphorylated and total levels of Akt and ERK were determined by Western blotting in brain samples obtained from untreated naive, time control, and PA/HIE animals at 24-48h survival (n=3-3-6,respectively)...
November 11, 2017: Life Sciences
https://www.readbyqxmd.com/read/29133711/an-unusual-case-of-acute-encephalitic-syndrome-is-it-acute-measles-encephalitis-or-subacute-sclerosing-panencephalitis
#18
Ravindra K Garg, Hardeep S Malhotra, Imran Rizvi, Neeraj Kumar, Amita Jain
Subacute sclerosing panencephalitis is a late complication of measles infection and develops usually 6 to 15 years after the primary measles infection. Fulminant subacute sclerosing panencephalitis is an infrequently encountered form wherein the disease rapidly progresses to death. A six-year old male child presented with fever, abnormal movements of the left side of body followed by weakness of the left side of the body, and involuntary abnormal movements of right upper and lower limbs. On examination, he was drowsy and was unable to communicate...
November 2017: Neurology India
https://www.readbyqxmd.com/read/29133642/frequency-of-primary-mutations-of-leber-s-hereditary-optic-neuropathy-patients-in-north-indian-population
#19
Anushree Mishra, Saranya Devi, Rohit Saxena, Neerja Gupta, Madhulika Kabra, Madhumita Roy Chowdhury
PURPOSE: Leber's hereditary optic neuropathy (LHON) is an inherited optic neuropathy characterized by subacute painless vision loss. The majority of LHON is caused due to one of the three primary mutations in the mitochondrial DNA (m.G3460A, m.G11778A, and m.T14484C). The frequency of these mutations differs in different populations. The purpose of this study is to observe the frequency of three common primary mutations in the North Indian population. METHODS: Forty LHON patients within the age group of 10-50 years underwent molecular testing for primary mutations...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29133324/effects-of-falls-prevention-interventions-on-falls-outcomes-for-hospitalised-adults-protocol-for-a-systematic-review-with-meta-analysis
#20
Susan C Slade, David L Carey, Anne-Marie Hill, Meg E Morris
INTRODUCTION: Falls are a major global public health problem and leading cause of accidental or unintentional injury and hospitalisation. Falls in hospital are associated with longer length of stay, readmissions and poor outcomes. Falls prevention is informed by knowledge of reversible falls risk factors and accurate risk identification. The extent to which hospital falls are prevented by evidence-based practice, patient self-management initiatives, environmental modifications and optimisation of falls prevention systems awaits confirmation...
November 12, 2017: BMJ Open
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