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streptococcus viridans

Oren I Feder, Konrad I Gruson
Septic arthritis of the shoulder girdle remains relatively uncommon, with Staphylococcus aureus and β-hemolytic streptococci the typical offending organisms in adult patients. Rare cases of Streptococcus viridans, an oral bacterium with low virulence, have been reported in the setting of septic arthritis, mostly involving the knee joint or the sternoclavicular joint. In this article, we report a case of Streptococcus mitis infection of the glenohumeral joint that likely resulted from hematogenous spread after oral trauma in a patient with poor underlying dentition...
September 2016: American Journal of Orthopedics
Stefano Mancini, Carmen Menzi, Frank Oechslin, Philippe Moreillon, José Manuel Entenza
Streptococcus gordonii and related species of oral viridans group streptococci (VGS) are common etiological agents of infective endocarditis (IE). We explored vaccination as a strategy to prevent VGS- IE, using a novel antigen presenting system based on non-genetically modified Lactococcus lactis displaying vaccinogens on its surface.Hsa and PadA are surface-located S. gordonii proteins implicated in platelet adhesion and aggregation, which are key steps in the pathogenesis of IE. This function makes them ideal targets for vaccination against VGS- IE...
October 10, 2016: Infection and Immunity
Stephen Starko Francis, Mateusz M Plucinski, Amelia D Wallace, Lee W Riley
Social network structure is a fundamental determinant of human health, from infectious to chronic diseases. However, quantitative and unbiased approaches to measuring social network structure are lacking. We hypothesized that genetic relatedness of oral commensal bacteria could be used to infer social contact between humans, just as genetic relatedness of pathogens can be used to determine transmission chains of pathogens. We used a traditional, questionnaire survey-based method to characterize the contact network of the School of Public Health at a large research university...
2016: PloS One
Serap Süzük, Banu Kaşkatepe, Mustafa Çetin
The viridans group Streptococci (VGS) are most abundant in the mouth; in some instances they might emerge as pathogens particularly in infective endocarditis (IE). In this study, we aimed to define and determine the susceptibility against antibiotics of VGS that are members of the oral microbiota of patients exhibiting a risk of developing IE. Forty-nine patients at risk of infective endocarditis were included in the study. Identification of the bacteria was performed using API STREP (bioMérieux, France). Gradient test strips (E-Test, France) were used to determine MIC of the bacteria against penicillin, ampicillin, and vancomycin...
September 1, 2016: Le Infezioni in Medicina
Bart Peeters, Paul Herijgers, Kurt Beuselinck, Willy E Peetermans, Marie-Christin Herregods, Stefanie Desmet, Katrien Lagrou
Identification of the causative pathogen of infective endocarditis is crucial for adequate management and therapy. A broad range PCR/electrospray ionization mass spectrometry (PCR/ESI-MS) technique was compared with broad-spectrum 16S rRNA PCR and amplicon sequencing (16S rRNA PCR) for detecting bacterial pathogens in 40 heart valves obtained from 34 definite infective endocarditis patients according to the modified Duke Criteria and six non-endocarditis patients. Concordance between both molecular techniques was 98% for being positive or negative, 97% for concordant identification up to genus level and 77% for concordant identification up to species level...
September 14, 2016: Journal of Clinical Microbiology
Xuan Zhang, Xiaoli Liu, Meifang Yang, Huihui Dong, Lichen Xv, Lanjuan Li
BACKGROUND: Endoscopic variceal ligation (EVL) is the endoscopic treatment of acute esophageal variceal hemorrhage, however, prophylaxis antibiotic during EVL is controversial. METHODS: We reported a 60-year-old man with diabetes, liver cirrhosis and hepatocellular carcinoma who received EVL for esophageal variceal haemorrhage. RESULTS: On the second day after EVL, the patient developed fever and chills. A week after EVL, the blood cultures were viridans streptococcus positive, and echocardiogram showed a vegetation on the cardiac valve...
August 2016: Medicine (Baltimore)
D Khalil, M Hultin, M U Rashid, B Lund
The study aimed to determine the effects of a single-dose antibiotic prophylaxis on normal oral microflora. A single dose of 2 g amoxicillin was given to 29 healthy volunteers. Saliva was collected before antibiotic administration (day 1), and again on days 2, 5, 10, 17 and 24 and subjected to culturing and antibiotic sensitivity analysis. Twenty-one per cent (6/29) of the individuals carried penicillin-V- and amoxicillin-resistant viridans streptococci before antibiotic administration. After a single dose of amoxicillin there was a significant reduction in Streptococcus salivarius on days 2 and 5, a significant reduction in other viridans streptococci on day 2 and the proportion of viridans streptococci with reduced susceptibility to amoxicillin was significantly increased on days 2 and 5...
August 26, 2016: Clinical Microbiology and Infection
Hiroya Miyamoto, Harumi Gomi, Haruhiko Ishioka, Taijiro Shirokawa
An 84-year-old man was admitted to our hospital with bloody sputum. He was found to have a right lower lobe wedge-shaped nodular lesion with chest X-ray and computed tomography of the chest. Ceftriaxone and minocycline were started empirically based on a working diagnosis of community-acquired pneumonia. Streptococcus parasanguinis was isolated with sputum cultures obtained on three consecutive days and was identified based on its biochemical properties. S. parasanguinis is a member of the sanguinis group of viridans Streptococci...
May 2016: Kansenshōgaku Zasshi. the Journal of the Japanese Association for Infectious Diseases
Juliette O Flam, Michael P Platt, Rachel Sobel, Anand K Devaiah, Christopher D Brook
BACKGROUND: Acute and chronic sinusitis in children and adults can spread to the orbit. Oral flora has been seen in orbital infections, but the extent of synergy between pathogens in such infections remains unknown. METHODS: A retrospective case series of patients with complicated sinusitis that involved the orbit from acute sinusitis who were admitted to a tertiary care hospital from January 2000 to December 2014 and who had surgical cultures obtained. Patients were identified by the International Classification of Diseases, Ninth Revision code for periorbital cellulitis, subperiosteal abscess, or orbital abscess...
July 2016: American Journal of Rhinology & Allergy
Margaret M Reynolds, Kerryl E Greenwood-Quaintance, Robin Patel, Jose S Pulido
PURPOSE: Endophthalmitis is a rare complication of intravitreal injection (IVI). It is recommended that povidone-iodine be the last agent applied before IVI. Patients have reported povidone-iodine application to be the most bothersome part of IVIs. Topical anesthetics have been demonstrated to have antibacterial effects. This study compared the minimum inhibitory concentration (MIC) of topical anesthetic eye drops (proparacaine 0.5%, tetracaine 0.5%, lidocaine 2.0%) and the antiseptic, 5...
July 2016: Translational Vision Science & Technology
Evgeny A Idelevich, Karsten Becker, Janne Schmitz, Dennis Knaack, Georg Peters, Robin Köck
Results of disk diffusion antimicrobial susceptibility testing depend on individual visual reading of inhibition zone diameters. Therefore, automated reading using camera systems might represent a useful tool for standardization. In this study, the ADAGIO automated system (Bio-Rad) was evaluated for reading disk diffusion tests of fastidious bacteria. 144 clinical isolates (68 β-haemolytic streptococci, 28 Streptococcus pneumoniae, 18 viridans group streptococci, 13 Haemophilus influenzae, 7 Moraxella catarrhalis, and 10 Campylobacter jejuni) were tested on Mueller-Hinton agar supplemented with 5% defibrinated horse blood and 20 mg/L β-NAD (MH-F, Oxoid) according to EUCAST...
2016: PloS One
Robert K Flamm, Paul R Rhomberg, David J Farrell, Ronald N Jones
Pexiganan, in Phase 3 clinical development for topical use, exhibited bactericidal activity in vitro against Gram-positive and -negative isolates and was also shown to have a low potential for resistance development in broth serial passage experiments. Susceptibility studies were performed against bacterial isolates (110 total from 2004 to 2013; primarily from skin and soft tissue infections) selected for elevated MIC values (non-wildtype [WT] distributions) to bacitracin, polymyxin B, neomycin, mupirocin, retapamulin, fusidic acid, or gentamicin...
September 2016: Diagnostic Microbiology and Infectious Disease
Astrid A T M Bosch, Evgeni Levin, Marlies A van Houten, Raiza Hasrat, Gino Kalkman, Giske Biesbroek, Wouter A A de Steenhuijsen Piters, Pieter-Kees C M de Groot, Paula Pernet, Bart J F Keijser, Elisabeth A M Sanders, Debby Bogaert
Birth by Caesarian section is associated with short- and long-term respiratory morbidity. We hypothesized that mode of delivery affects the development of the respiratory microbiota, thereby altering its capacity to provide colonization resistance and consecutive pathobiont overgrowth and infections. Therefore, we longitudinally studied the impact of mode of delivery on the nasopharyngeal microbiota development from birth until six months of age in a healthy, unselected birth cohort of 102 children (n=761 samples)...
July 2016: EBioMedicine
Ali M Bazzi, Ali A Rabaan, Zeyad El Edaily, Susan John, Mahmoud M Fawarah, Jaffar A Al-Tawfiq
Matrix-assisted laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometry facilitates rapid and accurate identification of pathogens, which is critical for sepsis patients. In this study, we assessed the accuracy in identification of both Gram-negative and Gram-positive bacteria, except for Streptococcus viridans, using four rapid blood culture methods with Vitek MALDI-TOF-MS. We compared our proposed lysis centrifugation followed by washing and 30% acetic acid treatment method (method 2) with two other lysis centrifugation methods (washing and 30% formic acid treatment (method 1); 100% ethanol treatment (method 3)), and picking colonies from 90 to 180min subculture plates (method 4)...
June 13, 2016: Journal of Infection and Public Health
Dalia Denapaite, Martin Rieger, Sophie Köndgen, Reinhold Brückner, Irma Ochigava, Peter Kappeler, Kerstin Mätz-Rensing, Fabian Leendertz, Regine Hakenbeck
Viridans streptococci were obtained from primates (great apes, rhesus monkeys, and ring-tailed lemurs) held in captivity, as well as from free-living animals (chimpanzees and lemurs) for whom contact with humans is highly restricted. Isolates represented a variety of viridans streptococci, including unknown species. Streptococcus oralis was frequently isolated from samples from great apes. Genotypic methods revealed that most of the strains clustered on separate lineages outside the main cluster of human S...
March 2016: MSphere
Howard S Faden
Streptococcus intermedius is a viridans Streptococcus belonging to the Anginosus group. In the past 7 years, it has been associated with abscesses in 48 children, 40% of whom had complicated and/or life-threatening illness. It was the sole pathogen in 35 cases. Seventy-five percent of the infections occurred in winter and spring. None occurred in infants younger than 1 year.
September 2016: Pediatric Infectious Disease Journal
Katarzyna Obszańska, Izabella Kern-Zdanowicz, Aleksandra Kozińska, Katarzyna Machura, Elzbieta Stefaniuk, Waleria Hryniewicz, Izabela Sitkiewicz
Streptococcus anginosus, Streptococcus intermedius and Streptococcus constellatus form a group of related streptococcal species, namely the Streptococcus Anginosus Group (SAG). The group, previously called "milleri" had been rarely described until 1980/1990 as source of infections. Nowadays SAG bacteria are often described as pathogens causing predominantly purulent infections. The number of infections is highly underestimated, as SAG strains are often classified in the microbiology laboratory as less virulent "viridans streptococci" Epidemiological situation regarding SAG infections in Poland has been unrecognized, therefore we performed a retrospective analysis of strains isolated between 1996 and 2012...
2016: Polish Journal of Microbiology
Salik Nazir, Saroj Lohani, Niranjan Tachamo, Priya Rajagopalan
Vertebral osteomyelitis due to Streptococcus viridans following a dental procedure is a rarely reported phenomenon. We discuss the case of a 67-year-old immunocompetent woman who presented with low back pain of 3 weeks duration associated with subjective fever and chills. On admission, the MRI of the lumbar spine showed L5-S1 vertebral osteomyelitis with associated paravertebral and epidural abscesses. Subsequently, detailed history was retaken and the patient reported having had a maxillary tooth extraction followed by a dental implant 2 months prior to the onset of her symptoms...
2016: BMJ Case Reports
Christiana T Vogkou, Nikolaos I Vlachogiannis, Leonidas Palaiodimos, Antonis A Kousoulis
Infective endocarditis (IE) incidence remains high with considerable fatality rates; guidelines for prophylaxis against IE are currently under review in some settings which highlights the importance of maintaining up-to-date epidemiological estimates about the most common microbial causes. The objective of this systematic review, following PRISMA guidelines, was to identify the most common microbial causes of IE in recent years. Medline was searched from January 1, 2003 to March 31, 2013 for all articles containing the term "infective endocarditis"...
August 2016: European Journal of Clinical Microbiology & Infectious Diseases
Godwin Ofikwu, Saqib Saeed, Alexius Ramcharan
No abstract text is available yet for this article.
April 2016: American Surgeon
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