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streptococcus viridans

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https://www.readbyqxmd.com/read/29410368/surveillance-of-tigecycline-activity-tested-against-clinical-isolates-from-a-global-north-america-europe-latin-america-and-asia-pacific-collection-2016
#1
Michael A Pfaller, Michael D Huband, Jennifer Streit, Robert K Flamm, Helio S Sader
Tigecycline and comparators were tested by reference broth microdilution method against 33,348 non-duplicate bacterial isolates collected prospectively in 2016 from medical centers in Asia-Pacific (3,443 isolates), Europe (13,530 isolates), Latin America (3,327 isolates), and United States (13,048 isolates). Among 7,098 Staphylococcus aureus isolates tested, >99.9% were inhibited by ≤0.5 mg/L of tigecycline (MIC50/90, 0.06/0.12 mg/L), including >99.9% of methicillin-resistant S. aureus and 100.0% of methicillin-susceptible S...
February 1, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29378719/surveillance-of-omadacycline-activity-tested-against-clinical-isolates-from-the-united-states-and-europe-report-from-the-sentry-antimicrobial-surveillance-program-2016
#2
Michael A Pfaller, Michael D Huband, Dee Shortridge, Robert K Flamm
Omadacycline was tested against 21,000 bacterial isolates collected prospectively from medical centers in Europe and the United States during 2016. Omadacycline was active against Staphylococcus aureus (MIC50/90, 0.12/0.25 mg/L) including MRSA; streptococci (MIC50/90, 0.06/0.12 mg/L) including Streptococcus pneumoniae, viridans group streptococci, and β-hemolytic streptococci; Enterobacteriaceae including Escherichia coli (MIC50/90, 0.5/2 mg/L); Haemophilus influenzae (MIC50/90, 1/1 mg/L); and Moraxella catarrhalis (MIC50/90, 0...
January 29, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29322242/utility-of-fosfomycin-as-antibacterial-prophylaxis-in-patients-with-hematologic-malignancies
#3
Tanya Zapolskaya, Sarah Perreault, Dayna McManus, Jeffrey E Topal
PURPOSE: Prolonged and profound neutropenia is common among hematology and hematopoietic stem cell transplant (HSCT) patients as a result of chemotherapy. The National Comprehensive Cancer Network (NCCN) and Infectious Diseases Society of America (IDSA) currently recommend antibacterial prophylaxis in patients who are deemed at intermediate or high risk for infection. Specifically, fluoroquinolone prophylaxis should be considered for high-risk neutropenic patients. However, with prolonged and frequent exposure to fluoroquinolones, these high-risk patients may develop resistance to these agents...
January 10, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29279791/pulmonary-mycobacterium-avium-intracellulare-complex-infection-in-an-infant-a-silent-and-coincidental-finding
#4
Vishal Naik, Pui-Ying Iroh Tam, William Gershan, Andrew A Colin, Nadir Demirel
An 11-month-old healthy infant girl was noted to have left lower lobe (LLL) opacities on chest X-ray (CXR) after developing desaturations during an elective cochlear implant surgery. Repeat CXR 10 days later revealed hyperexpansion of the left lung and persistent LLL opacity. Chest computerized tomography revealed enlarged mediastinal lymph nodes, left mainstem bronchial obstruction, and nodular opacities. Bronchoscopic biopsy of the endobronchial tissue revealed multiple necrotizing granulomas and grew Mycobacterium avium-intracellulare, Streptococcus viridans, and Actinomyces odontolyticus...
December 1, 2017: Pediatric Allergy, Immunology, and Pulmonology
https://www.readbyqxmd.com/read/29260105/invasive-streptococcus-viridans-sphenoethmoiditis-leading-to-an-orbital-apex-syndrome
#5
Lance Bodily, Jenny Yu, Dante Sorrentino, Barton Branstetter
Purpose: Orbital apex syndrome due to spread of infectious sinusitis is a serious disease, often with an insidious presentation with few ophthalmic signs and symptoms. Failure to recognize and treat infectious orbital apex syndrome early portends a grave prognosis, including profound, permanent visual loss and potentially death. Herein we describe a representative case and discuss the relevant aspects of prompt diagnosis and treatment. Observations: An unusual case of infectious orbital apex syndrome due to contiguous spread of Streptococcus viridans sphenoethmoiditis in a hospitalized, immunosuppressed patient with acute myelogenous leukemia is presented...
December 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29191537/risk-factors-and-microbiology-of-meningitis-and-or-bacteremia-after-transsphenoidal-surgery-for-pituitary-adenoma
#6
Yu Jin, Xiaohai Liu, Lu Gao, Xiaopeng Guo, Qiang Wang, Xinjie Bao, Kan Deng, Yong Yao, Ming Feng, Wei Lian, Renzhi Wang, Qiwen Yang, Yao Wang, Bing Xing
OBJECTIVE: To investigate the incidence, bacteriological features, and risk factors of post- transsphenoidal surgery (TSS) meningitis and/or bacteremia. METHODS: This retrospective study included 3242 patients who underwent TSS for pituitary adenoma at the Dept. of Neurosurgery of Peking Union Medical College Hospital between January 2012 and December 2016. Clinical data for patients with and without post-TSS meningitis and/or bacteremia were compared and analyzed...
November 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29178882/characterization-and-susceptibility-of-streptococci-and-enterococci-isolated-from-nile-tilapia-oreochromis-niloticus-showing-septicaemia-in-aquaculture-and-wild-sites-in-egypt
#7
Kamelia M Osman, Khalid S Al-Maary, Aymen S Mubarak, Turki M Dawoud, Ihab M I Moussa, Mai D S Ibrahim, Ashgan M Hessain, Ahmed Orabi, Nehal M Fawzy
BACKGROUND: The present investigation was an endeavor into the elucidation of the disease-causing pathogen of streptococcosis in Nile tilapia (Oreochromis niloticus) in Egypt affecting adult fish cultured and wild fish in the Nile river. Fish were obtained from commercial fishermen, collected as part of their routine fishing activities. The researchers observed the routine fishing process and selected fish for use in the study, at the point of purchase from the fisherman. RESULTS: Diseased fish showed exophthalmia with accumulation of purulent and haemorrhagic fluid around eyes, and ventral petechial haemorrhages...
November 25, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29148386/human-case-of-streptococcus-suis-disease-ontario-canada
#8
Jeisa Gomez-Torres, Asim Nimir, James Cluett, Anita Aggarwal, Sameer Elsayed, Deirdre Soares, Sarah Teatero, Yan Chen, Marcelo Gottschalk, Nahuel Fittipaldi
We report a case of Streptococcus suis human disease in Ontario, Canada, caused by a serotype 2 strain genotypically similar to those commonly isolated from pigs in North America. Initially, the isolate was misidentified as a viridans group Streptococcus. Human S. suis infections may be underdiagnosed in North America.
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28981383/systemic-moxifloxacin-in-streptococcus-viridans-endophthalmitis
#9
Ki Yup Nam, Sang Joon Lee, Jung Yeul Kim
PURPOSE: To evaluate the effectiveness of prophylactic systemic moxifloxacin in a rabbit model of Streptococcus viridans (S. viridans) endophthalmitis. METHODS: Animals (n=60) were divided into three groups. Intravenous moxifloxacin, vancomycin, normal saline was administered to 20 animals in each group and two hours later, 10(4) colony-forming units (CFU) of S. salivarius were intravitreally injected into the left eye. Intravenous antibiotics injection was repeated on days 1, 2, and 3 after inoculation...
October 5, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28961701/zaaps-program-results-for-2015-an-activity-and-spectrum-analysis-of-linezolid-using-clinical-isolates-from-medical-centres-in-32-countries
#10
Michael A Pfaller, Rodrigo E Mendes, Jennifer M Streit, Patricia A Hogan, Robert K Flamm
Objectives: To report the linezolid in vitro activity obtained during the 2015 ZAAPS Program. Methods: In total, 7587 organisms causing documented infections were consecutively collected in 65 centres in 32 ex-USA countries. Broth microdilution susceptibility testing was performed. Isolates displaying linezolid MIC results of ≥ 4 mg/L were molecularly characterized. Results: Linezolid inhibited >99.9% of Staphylococcus aureus at ≤ 2 mg/L, with MIC50 results of 1 mg/L, regardless of methicillin resistance...
November 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28949429/predictors-of-visual-outcome-and-the-role-of-early-vitrectomy-in-streptococcal-endophthalmitis
#11
Emil D Kurniawan, John R Rocke, Sukhpal S Sandhu, Penelope J Allen
IMPORTANCE: Streptococcal endophthalmitis has devastating sequelae. This study aims to identify factors which may be targeted to optimize patient outcomes. BACKGROUND: This study investigated characteristics influencing visual outcomes and the role of early vitrectomy. DESIGN: Retrospective observational case series of consecutive patients was conducted. PARTICIPANTS: All patients with a culture-positive diagnosis of streptococcal endophthalmitis treated at a tertiary ophthalmology referral centre between July 1997 and February 2012 were included...
September 26, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28828970/antimicrobial-resistance-patterns-of-the-gram-positive-bacteria-isolated-from-children-with-bloodstream-infection-in-an-iranian-referral-hospital-a-6-year-study
#12
Setareh Mamishi, Babak Pourakbari, Shima Mahmoudi, Mina Moradzadeh, Masoumeh Mahzari, Mohammad TaghiHaghi Ashtiani, Parin Tanzifi
BACKGROUND: Bloodstream infections (BSI) are considered as a serious cause of morbidity and mortality in pediatricschildren. The aim of this study was to depict report the common Gram-positive bacteria (GPB) responsible for bloodstream infections in children and determine their antimicrobial resistance patterns in Children Medical Center Hospital (CMC), ) Hospital, Tehran, Iran. METHODS: This retrospective study was conducted within a six-year period (March 2011 to September 2016) for pediatric patients with BSI...
August 21, 2017: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/28776170/viridans-group-streptococci-bloodstream-infections-in-neutropenic-adult-patients-with-hematologic-malignancy-single-center-experience
#13
J Radocha, P Paterová, A Zavřelová, B Víšek, F Gabalec, H Žemličková, P Žák
Viridans group streptococci bloodstream infections (VGS BSI) remain a significant cause of mortality and morbidity in patients with severe neutropenia. The goal of our study was to evaluate clinical course and microbiological susceptibility of VGS BSI at our center. Retrospective analysis of all microbiologically documented bloodstream infections caused by VGS during the 9-year time period (from January 2006 until December 2014) was carried out. Only patients with severe neutropenia (< 500/μL) were included in the study...
August 3, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28756939/bacteriology-of-peritonsillar-abscess-the-changing-trend-and-predisposing-factors
#14
Yi-Wen Tsai, Yu-Hsi Liu, Hsing-Hao Su
INTRODUCTION: Peritonsillar abscess is the most common deep neck infection. The infectious microorganism may be different according to clinical factors. OBJECTIVE: To identify the major causative pathogen of peritonsillar abscess and investigate the relationship between the causative pathogen, host clinical factors, and hospitalization duration. METHODS: This retrospective study included 415 hospitalized patients diagnosed with peritonsillar abscess who were admitted to a tertiary medical center from June 1990 to June 2013...
July 17, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28737874/-brain-abscess-in-children-ten-years-of-experience-in-a-third-level-pediatric-hospital
#15
Martín Brizuela, Guadalupe Pérez, Soledad Martiren, Ana N Varela Baino, Carola Cedillo, Silvina Ruvinsky, Carolina Epelbaum, Adela Isasmendi, Mirta Litterio, José L Pinheiro, Rosa Bologna
Brain abscess is a focal infection that occurs with a frequency of 0.3-1.3 cases per 100,000 people/year. We describe the epidemiology, clinical and microbiology characteristics of 38 children diagnosed with brain abscess hospitalized between 4/1/2005 and 12/31/2015 at Hospital de Pediatría "Prof. Dr. Juan P. Garrahan" in Buenos Aires City. Twenty-four patients were male. The median age was 132 months. Predisposing factors were detected in 25 children. The median evolution from onset of symptoms to the visit was 7 days...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28727951/in-vitro-activity-of-telavancin-against-clinically-important-gram-positive-pathogens-from-69-u-s-medical-centers-2015-potency-analysis-by-u-s-census-divisions
#16
Michael A Pfaller, Helio S Sader, Robert K Flamm, Mariana Castanheira, Jennifer I Smart, Rodrigo E Mendes
A total of 8,072 gram-positive isolates collected from 69 medical centers among all 9 U.S. Census Divisions during the 2015 SENTRY Antimicrobial Surveillance Program were included. Telavancin had minimal inhibitory concentration (MIC)50 and MIC90 values of 0.03/0.06 μg/mL, respectively, against methicillin-susceptible (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). Similar activity was also observed among coagulase-negative staphylococci (MIC50/90, 0.03/0.06 μg/ml; 100.0% inhibited by ≤0...
September 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28681536/mycotic-aneurysm-of-the-root-of-left-subclavian-artery-associated-with-aortic-coarctation-discovered-by-echocardiography
#17
Ming-Dan Deng, Xin Wei, Wen Zhang, Hong Tang
A 16-year-old girl was admitted with a 7-month history of recurrent fever, weight loss of 5 kg, and general poor health status. Blood culture was positive with Streptococcus viridans. Transthoracic echocardiography established an aneurysm of the root of left subclavian artery, associated with an aortic coarctation just before the origin of the left subclavian artery with a velocity of 4.8 cm/s. Three-dimensional echocardiography demonstrated the entire inner structure of the aneurysm. Computed tomography reconstruction confirmed the presence of aortic coarctation and mycotic aneurysm, it also revealed an aberrant right subclavian artery...
July 6, 2017: Echocardiography
https://www.readbyqxmd.com/read/28681361/top-down-lesa-mass-spectrometry-protein-analysis-of-gram-positive-and-gram-negative-bacteria
#18
Klaudia I Kocurek, Leanne Stones, Josephine Bunch, Robin C May, Helen J Cooper
We have previously shown that liquid extraction surface analysis (LESA) mass spectrometry (MS) is a technique suitable for the top-down analysis of proteins directly from intact colonies of the Gram-negative bacterium Escherichia coli K-12. Here we extend the application of LESA MS to Gram-negative Pseudomonas aeruginosa PS1054 and Gram-positive Staphylococcus aureus MSSA476, as well as two strains of E. coli (K-12 and BL21 mCherry) and an unknown species of Staphylococcus. Moreover, we demonstrate the discrimination between three species of Gram-positive Streptococcus (Streptococcus pneumoniae D39, and the viridans group Streptococcus oralis ATCC 35037 and Streptococcus gordonii ATCC35105), a recognized challenge for matrix-assisted laser desorption ionization time-of-flight MS...
October 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28640003/infections-associated-with-streptococcus-constellatus-in-children
#19
Howard Faden, Mustafa Mohmand
Streptococcus constellatus is a viridans Streptococcus belonging to the Anginosus group. It was associated with abscesses in 37 children, 80% of whom had acute appendicitis with perforation and abscess formation in 50%. None of the children was <3 years of age.
November 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28546690/update-on-the-epidemiology-and-antibiotic-resistance-of-ocular-infections
#20
Darlene Miller
PURPOSE: The purpose of this review is to provide an update on the epidemiology and current antibiotic-resistant threats in ophthalmology. METHODS: Trends in frequency and antibiotic-nonsusceptible profiles during an 11 year-period (2005-2015) were evaluated and compared with the 5-year Antibiotic Resistance Monitoring in Ocular Microorganism (ARMOR) study. RESULTS: Trends in the current review confirmed the continued high rates of fluoroquinolone nonsusceptbility circulating among ocular methicillin-susceptible Staphylococcus aureus, methicillin-susceptible Staphylococcus epidermidis, methicillin-resistant S...
January 2017: Middle East African Journal of Ophthalmology
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