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https://www.readbyqxmd.com/read/28719475/allergic-contact-dermatitis-from-methylisothiazolinone-in-residential-wall-paint
#1
Molly C Goodier, Linda Ljungberg, Christina Persson, Malin Engfeldt, Magnus Bruze, Erin M Warshaw
A 33-year-old woman presented to our clinic for suspected photoallergic contact dermatitis with a recent episode of severe, vesicular dermatitis involving exposed skin and correlating with relocation to a new home. Biopsy results showed spongiotic and lichenoid dermatitis with eosinophils. Patch test results showed a very strong (+++) reaction to methylisothiazolinone (MI), mild (+) reaction to MI/methylchloroisothiazolinone, and no reaction to benzisothiazolinone. These allergens were found in several personal products...
July 2017: Dermatitis
https://www.readbyqxmd.com/read/28694695/relationship-between-blood-eosinophils-clinical-characteristics-and-mortality-in-patients-with-copd
#2
Maeva Zysman, Gaëtan Deslee, Denis Caillaud, Pascal Chanez, Roger Escamilla, Isabelle Court-Fortune, Pascale Nesme-Meyer, Thierry Perez, Jean-Louis Paillasseur, Christophe Pinet, Gilles Jebrak, Nicolas Roche, Pierre-Régis Burgel
In patients with COPD, there is controversy regarding the association of blood eosinophil (Eos) levels with 1) exacerbation frequency and 2) the effect of inhaled corticosteroids for prevention of exacerbations. To determine whether Eos define subgroups of patients exhibiting attributes of COPD clinical phenotypes, we compared clinical features and mortality rates in COPD patients from the Initiatives BPCO French cohort categorized using different thresholds of blood Eos levels. The following data were collected at inclusion: medical and smoking history, occupational exposures, dyspnea, cough and sputum production, exacerbations in the previous year, history of allergy and asthma, nasal symptoms, body mass index, St George Respiratory Questionnaire (SGRQ) total score, post-bronchodilator spirometry, comorbidities, and medications...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28681396/association-of-atopy-and-tentative-diagnosis-of-skin-cancer-results-from-occupational-skin-cancer-screenings
#3
I Schäfer, P Mohr, N Zander, R Fölster-Holst, M Augustin
BACKGROUND: The relationship between atopic conditions and carcinoma of the skin has been described inconsistently. Population-based data providing information on atopic diseases as well as on skin-cancer are sparse. OBJECTIVE: To determine the correlation between atopy and prevalence of precanceroses, nonmelanoma skin-cancer and malignant melanoma (MM), while taking into account known risk factors for skin cancer. METHODS: Data from occupational skin cancer screenings were analysed in a cross-sectional study...
July 6, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28675438/biological-monitoring-of-dermal-and-air-exposure-to-cobalt-at-a-swedish-hard-metal-production-plant-does-dermal-exposure-contribute-to-uptake
#4
Maria Klasson, Magnus Lindberg, Ing-Liss Bryngelsson, Helena Arvidsson, Carin Pettersson, Bente Husby, Håkan Westberg
BACKGROUND: Occupational exposure to cobalt is well established in hard metal manufacture. Cobalt is known to cause contact allergy, asthma, hard metal lung disease, and lung cancer. The relationship between skin exposure and uptake determined in blood has not been extensively investigated. OBJECTIVE: To examine whether skin and inhalable air exposure to cobalt contributes to uptake, determined as cobalt in blood, in a hard metal manufacturing factory. METHODS: The amount of cobalt on the skin found with an acid wash technique, the air concentrations of inhalable cobalt and cobalt blood concentrations were determined and correlated in exposed workers...
July 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28670248/allergic-contact-dermatitis-pattern-in-kuwait-nickel-leads-the-pack-in-depth-analysis-of-nickel-allergy-based-on-the-results-from-a-large-prospective-patch-test-series-report
#5
Nawaf Almutairi, Fahad Almutawa
INTRODUCTION: Contact dermatitis is a relatively common dermatosis reported among several population groups from all around the globe. However, the data from Kuwait is unavailable. Patch tests are essential for the diagnosis of contact sensitization. AIM: To determine a relative frequency and pattern of sensitizers to different allergens in patients of suspected contact dermatitis in Kuwait and, also to study the role of the commonest sensitizer in detail. MATERIAL AND METHODS: Patch tests were performed in 2461 consecutive patients with a clinical diagnosis of contact dermatitis seen at our hospital between September 1, 2014 and August 31, 2015...
June 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28641054/behavioural-interventions-to-reduce-nickel-exposure-in-a-nickel-processing-plant
#6
Krassi Rumchev, Helen Brown, Amanda Wheeler, Gavin Pereira, Jeff Spickett
Nickel is a widely used material in many industries. Although, there is enough evidence that occupational exposure to nickel may cause respiratory illnesses, allergies and even cancer, it is not possible to stop the use of nickel in occupational settings. Nickel exposure, however, can be controlled and reduced significantly in workplaces. The main objective of this study was to assess if educational intervention of hygiene behaviour could reduce nickel exposure among Indonesian nickel smelter workers. Participants were randomly assigned to three intervention groups (n = 99)...
June 22, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28627111/european-surveillance-system-on-contact-allergies-essca-results-with-the-european-baseline-series-2013-14
#7
W Uter, J C Amario-Hita, A Balato, B Ballmer-Weber, A Bauer, A Belloni Fortina, A Bircher, M M U Chowdhury, S M Cooper, A Dugonik, R Gallo, A Giménez-Arnau, J D Johansen, S M John, M Kieć-Świerczyńska, T Kmecl, B Kręcisz, F Larese Filon, V Mahler, M Pesonen, T Rustemeyer, A Sadowska-Przytocka, J Sánchez-Perez, S Schliemann, M L Schuttelaar, D Simon, R Spiewak, S Valiukeviciene, E Weisshaar, I R White, S M Wilkinson
BACKGROUND: Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, a consequence of introduction of new substances, new products or formulations, and regulatory intervention, the spectrum of contact sensitisation changes. OBJECTIVE: To evaluate the current spectrum of contact allergy to allergens present in the European baseline series (EBS) across Europe. METHODS: Retrospective analysis of data collected by the European Surveillance System on Contact Allergies (ESSCA, www...
June 19, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28589108/asthma-and-allergic-rhinitis-correlation-in-palm-tree-workers-of-jahrom-city-in-2016
#8
Mohammad Amin Farahmand Fard, Narges Khanjani, Aliasghar Arabi Mianroodi, Ahad Ashrafi Asgarabad
INTRODUCTION: Allergic rhinitis and asthma can be related to occupation. The present study aimed to investigate the correlation between asthma or allergic rhinitis and employment in the palm tree gardens of Jahrom, Iran. MATERIALS AND METHODS: This was a cross-sectional study including 50 palm tree garden workers and a control group of 50 office employees. Data collection included demographics, as well as standard International Study of Asthma and Allergies in Childhood (ISAAC) and A New Symptom-Based Questionnaire for Predicting the Presence of Asthma (ASQ) questionnaires...
May 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28543634/thaumatin-and-gum-arabic-allergy-in-chewing-gum-factory-workers
#9
Mattias P Tschannen, Ulrich Glück, Andreas J Bircher, Ingmar Heijnen, Claudia Pletscher
Thaumatin is a sweetener and flavor modifier commonly used in the food industry. Likewise, gum arabic is widely used as a food stabilizer and thickening agent. We report here that a powder mixture composed of 10% thaumatin and 90% gum arabic led to allergic symptoms in the upper airways in occupationally exposed individuals: four of eight workers of a chewing gum factory exposed to this powder mixture had pronounced rhinitis. A positive skin prick test result for pure thaumatin was obtained in all four individuals with rhinitis of whom two also had a positive skin prick test result for pure gum arabic and gum arabic-specific IgE...
July 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28516256/-skin-diseases-associated-with-environmental-factors
#10
REVIEW
Vera Mahler
BACKGROUND: Multiple environmental exposures may derange the regulatory and repair mechanisms of the skin and lead to dermatological disease. OBJECTIVES: Provide an overview of non-allergic skin diseases associated with environmental factors. MATERIALS AND METHODS: Review of current scientific evidence for associations of non-allergic skin diseases with environmental exposures: irritation, chemicals, infection, UV-radiation, temperature. RESULTS: Predisposition (constitution e...
June 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28512370/occupational-contact-allergy-to-omeprazole-and-ranitidine
#11
Inmaculada Herrera-Mozo, Pere Sanz-Gallen, Gabriel Martí-Amengual
Omeprazole is a proton pump inhibition and ranitidine is an H2 histamine receptor antagonist widely used in the treatment of gastroesophageal reflex disease, peptic ulcer disease, Zollinger-Ellison syndrome and as a protector of the gastric mucosae. We report a case of occupational contact allergy to omeprazole and ranitidine. A 48-year-old man, with no pre-existing history of atopy or lifestyle factors. He neither had any medical history of consumption of drugs such as ranitidine and omeprazole. He worked for 19 months in the pharmaceutical company that manufactured ranitidine base...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28509715/epidemic-of-isothiazolinone-allergy-in-north-america-prevalence-data-from-the-north-american-contact-dermatitis-group-2013-2014
#12
Matthew J Zirwas, Dathan Hamann, Erin M Warshaw, Howard I Maibach, James S Taylor, Denis Sasseville, Joel G DeKoven, Anthony F Fransway, C G Toby Mathias, Kathryn A Zug, Vincent A DeLeo, Joseph F Fowler, James G Marks, Melanie D Pratt, Donald V Belsito
BACKGROUND: Preservative sensitivity patterns evolve with changing use patterns in products. During the last decade, the use of methylisothiazolinone (MI) at higher concentrations in both leave-on and rinse-off products has significantly increased. This is the first North American Contact Dermatitis Group reporting cycle that includes both methylchloroisothiazolinone (MCI)/MI and MI data. OBJECTIVE: The aim of this study was to report the prevalence of isothiazolinone allergy (MCI/MI and MI) in the North American Contact Dermatitis Group patch-test population from January 1, 2013, to December 31, 2014...
May 2017: Dermatitis
https://www.readbyqxmd.com/read/28483971/association-of-household-cleaning-agents-and-disinfectants-with-asthma-in-young-german-adults
#13
Tobias Weinmann, Jessica Gerlich, Sabine Heinrich, Dennis Nowak, Erika von Mutius, Christian Vogelberg, Jon Genuneit, Stefanie Lanzinger, Saba Al-Khadra, Tina Lohse, Irina Motoc, Viola Walter, Katja Radon
OBJECTIVES: We scrutinised the association of private use of household sprays and disinfectants with asthma incidence in young adults in the transition from school to working life. METHODS: Between 2007 and 2009,2051 young adults aged 19-24 years living in two major German cities took part in the Study on Occupational Allergy Risks II. Self-reported exposure to household sprays and disinfectants was characterised according to a composite score for frequency of use as no use (score=0), low use (score between 1 and the median), medium use (score between the median and the 90th percentile) and high use (score above the 90th percentile)...
May 8, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28457804/the-clinical-pharmacology-of-non-sedating-antihistamines
#14
REVIEW
Kazuhiko Yanai, Takeo Yoshikawa, Ai Yanai, Tadaho Nakamura, Tomomitsu Iida, Rob Leurs, Manabu Tashiro
We previously reported on brain H1 receptor occupancy measurements of antihistamines in human brain using [(11)C]doxepin and positron emission tomography (PET). We proposed the use of brain H1 receptor occupancy to classify antihistamines objectively into three categories of sedating, less-sedating, and non-sedating antihistamines according to their sedative effects. Non-sedating antihistamines are recommended for the treatment of allergies such as pollinosis and atopic dermatitis because of their low penetration into the central nervous system...
April 27, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28449346/airborne-allergic-contact-dermatitis-caused-by-isothiazolinones-in-water-based-paints-a-retrospective-study-of-44-cases
#15
Emmanuelle Amsler, Olivier Aerts, Nadia Raison-Peyron, Michèle Debons, Brigitte Milpied, Françoise Giordano-Labadie, Julie Waton, Marie C Ferrier-Le Bouëdec, Isabelle Lartigau, Catherine Pecquet, Haudrey Assier, Martine Avenel-Audran, Claire Bernier, Florence Castelain, Evelyne Collet, Marie-Noëlle Crépy, Nathalie Genillier, Pascal Girardin, Pauline Pralong, Florence Tetart, Dominique Vital-Durand, Angele Soria, Annick Barbaud
BACKGROUND: Airborne allergic contact dermatitis caused by paints containing isothiazolinones has been recognized as a health hazard. OBJECTIVES: To collect epidemiological, clinical and patch test data on airborne allergic contact dermatitis caused by isothiazolinone-containing paints in France and Belgium. METHODS: A descriptive, retrospective study was initiated by the Dermatology and Allergy Group of the French Society of Dermatology, including methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI)- and/or MI-sensitized patients who developed airborne allergic contact dermatitis following exposure to isothiazolinone-containing paint...
April 27, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28447136/-environmental-health-relevance-of-airborne-microorganisms-in-ambient-and-indoor-air
#16
REVIEW
Sandra M Walser, Bernhard Brenner, Stefanie Heinze, Regine Szewzyk, Eike Wolter, Caroline E W Herr
Airborne microorganisms occur ubiquitously in the ambient air. Besides allergic and irritative-toxic effects, they can cause infections after inhalation. Occupational studies have shown that an increased incidence of respiratory diseases is found in adequately exposed workers. In addition to respiratory diseases, severe systemic infections can also occur in particular cases, such as in the case of a hantavirus infection that is recognized as an occupational disease. In studies from environmental medicine, respiratory diseases have also been observed in residents living in the vicinity of livestock facilities and evaporative cooling towers...
April 26, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28437767/building-integrated-agriculture-a-first-assessment-of-aerobiological-air-quality-in-rooftop-greenhouses-i-rtgs
#17
Mireia Ercilla-Montserrat, Rebeca Izquierdo, Jordina Belmonte, Juan Ignacio Montero, Pere Muñoz, Concepción De Linares, Joan Rieradevall
Building-integrated rooftop greenhouse (i-RTG) agriculture has intensified in recent years, due to the growing interest in the development of new agricultural spaces and in the promotion of food self-sufficiency in urban areas. This paper provides a first assessment of the indoor dynamics of bioaerosols in an i-RTG, with the aim of evaluating biological air quality in a tomato greenhouse near Barcelona. It evaluates the greenhouse workers' exposure to airborne pollen and fungal spores in order to prevent allergy problems associated with occupational tasks...
November 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28429304/new-perspectives-on-the-diagnosis-of-allergy-to-anisakis-spp
#18
REVIEW
Ignacio Moneo, Noelia Carballeda-Sangiao, Miguel González-Muñoz
PURPOSE OF REVIEW: To compare the prevalence of sensitization in different countries based on specific IgE values and to evaluate the use of isolated native or recombinant allergens for diagnosis. RECENT FINDINGS: Isolated allergens help in the diagnosis of truly sensitized patients avoiding false positives due to cross-reactions. Their use is therefore highly recommended, especially when used as a combination of several relevant allergens. The use of purified allergens allows an accurate diagnosis and this has led to three important findings: (1) in addition to the digestive route of sensitization, occupational and non-digestive exposure seems to be clinically relevant...
May 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28425114/a-multi-institutional-joint-study-of-contact-dermatitis-related-to-hair-colouring-and-perming-agents-in-japan
#19
Akiko Ito, Kazue Nishioka, Hiromi Kanto, Akiko Yagami, Shigeki Yamada, Mariko Sugiura, Chihiro Yasunaga, Keiko Yoshii, Hiromi Kobayashi, Atsuko Adachi, Yuko Ikezawa, Kumiko Washizaki, Shigeki Inui, Hitoshi Miyazawa, Naoki Oiso, Tokio Nakata, Kayoko Matsunaga
BACKGROUND: In Japan, allergic contact dermatitis caused by hair colouring agents is a considerable problem for those occupationally exposed and also for consumers. Over the last 20 years, p-phenylenediamine (PPD) has been a common allergen, with ∼7% positive patch test reactions. OBJECTIVES: To investigate which ingredients caused allergic contact dermatitis related to hair dye and perming solutions in Japan, to assess whether PPD is suitable for screening for hair dye allergy, and to propose allergens for a Japanese hairdresser series...
April 20, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28400946/the-state-of-asthma-epidemiology-an-overview-of-systematic-reviews-and-their-quality
#20
Jon Genuneit, Annina M Seibold, Christian J Apfelbacher, George N Konstantinou, Jennifer J Koplin, Stefania La Grutta, Kirsty Logan, Carsten Flohr, Michael R Perkin
BACKGROUND: Recently, we have published an overview of systematic reviews in allergy epidemiology and identified asthma as the most commonly reviewed allergic disease. Building on this work, we aimed to investigate the quality of systematic reviews in asthma using the AMSTAR checklist and to provide a reference for future, more in-depth assessment of the extent of previous knowledge. METHODS: We included all 307 systematic reviews indexed with asthma, including occupational asthma, and/or wheeze from our previous search in PubMed and EMBASE up to December 2014 for systematic reviews on epidemiological research on allergic diseases...
2017: Clinical and Translational Allergy
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