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https://www.readbyqxmd.com/read/29683922/a-review-of-accelerometer-based-activity-monitoring-in-cancer-survivorship-research
#1
Carolyn J Peddle-McIntyre, Vinicius Cavalheri, Terry Boyle, Joanne A McVeigh, Emily Jeffery, Brigid M Lynch, Jeff K Vallance
BACKGROUND: In the cancer survivorship context, physical activity and sedentary behaviour have been measured using different methods and tools. PURPOSE: To conduct a narrative review of published research in cancer survivor populations to summarise the quality and identify gaps in reporting on accelerometer data collection, data processing, and outcome measures in cancer survivors. METHODS: An initial PubMed® search of papers published in English was conducted in January 2017, and a final search was conducted in May 2017...
April 21, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29683834/the-effect-of-preoperative-exercise-on-upper-extremity-recovery-following-breast-cancer-surgery-a-systematic-review
#2
Ajax Yang, Jonas Sokolof, Amitabh Gulati
Prehabilitation benefits among patients undergoing various oncological surgeries have been demonstrated. However, the effects of presurgical exercise and fitness on postoperative ipsilateral upper extremity recovery outcomes in patients with breast cancer surgery are less evident. A systematic review was performed to assess the effects of preoperative exercise and fitness on postmastectomy recovery. Systematic literature search was performed in 12 electronic databases. Study eligibility was accessed using the PICOS (Participants, Interventions, Comparison, Outcome and Study Design) criteria...
April 20, 2018: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/29683152/response-effects-of-physical-activity-on-depressive-symptoms-during-breast-cancer-survivorship-a-meta-analysis-of-randomised-control-trials
#3
COMMENT
Efrossini D Patsou, Michalis V Karamouzis
No abstract text is available yet for this article.
2018: ESMO Open
https://www.readbyqxmd.com/read/29682216/physical-training-interventions-for-children-and-teenagers-affected-by-acute-lymphoblastic-leukemia-and-related-treatment-impairments
#4
REVIEW
Carolina Simioni, Giorgio Zauli, Alberto M Martelli, Marco Vitale, Simona Ultimo, Daniela Milani, Luca M Neri
A decreased physical fitness has been reported in patients and survivors of acute lymphoblastic leukemia (ALL). This is influenced by the negative effects of the disease and by the treatments of childhood cancer. In the past, children were advised to recover in bed, and to take as much relax as possible. Nowadays, it is considered that too much immobility may result in a further decrease of physical fitness and functioning. Exercise training for ALL children has frequently been reported to improve physical fitness and the well-being of the children, since it prevents the negative effects of a sedentary life-style, such as obesity and a poor skeletal health...
March 30, 2018: Oncotarget
https://www.readbyqxmd.com/read/29678976/fostering-active-living-and-healthy-eating-through-understanding-physical-activity-and-dietary-behaviours-of-arabic-speaking-adults-a-cross-sectional-study-from-the-middle-east
#5
Tam Truong Donnelly, Tak Shing Fung, Al-Anoud Bint Mohammad Al-Thani
OBJECTIVES: Physical inactivity and unhealthy diets increase the risk for diabetes, cardiovascular diseases and cancer. Many people in Qatar are sedentary and consume diets high in fats, salt and sugar. The purpose of this study was to determine physical activity levels, food habits and understand the variables that might predict physical activity and healthy eating behaviours among Arabic-speaking adults living in the State of Qatar. SETTING: A cross-sectional community-based survey was conducted with 1606 Arab adults ≥18 years of age from March 2013 to June 2015...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678262/tolfenamic-acid
#6
Sofia Ahmed, Muhammad Ali Sheraz, Iqbal Ahmad
Tolfenamic acid (TA) is a nonsteroidal antiinflammatory drug and belongs to the group of fenamates. It is used as a potent pain reliever in the treatment of acute migraine attacks, and disorders like dysmenorrhea, rheumatoid, and osteoarthritis. TA has shown excellent in vitro antibacterial activity against certain ATCC strains of bacteria when complexed with bismuth(III). It has also been reported to block pathological processes associated with Alzheimer's disease. In the recent past, TA has also been used as a novel anticancer agent for the treatment of various cancers...
2018: Profiles of Drug Substances, Excipients, and related Methodology
https://www.readbyqxmd.com/read/29676998/an-epigenetic-biomarker-of-aging-for-lifespan-and-healthspan
#7
Morgan E Levine, Ake T Lu, Austin Quach, Brian H Chen, Themistocles L Assimes, Stefania Bandinelli, Lifang Hou, Andrea A Baccarelli, James D Stewart, Yun Li, Eric A Whitsel, James G Wilson, Alex P Reiner, Abraham Aviv, Kurt Lohman, Yongmei Liu, Luigi Ferrucci, Steve Horvath
Identifying reliable biomarkers of aging is a major goal in geroscience. While the first generation of epigenetic biomarkers of aging were developed using chronological age as a surrogate for biological age, we hypothesized that incorporation of composite clinical measures of phenotypic age that capture differences in lifespan and healthspan may identify novel CpGs and facilitate the development of a more powerful epigenetic biomarker of aging. Using an innovative two-step process, we develop a new epigenetic biomarker of aging, DNAm PhenoAge, that strongly outperforms previous measures in regards to predictions for a variety of aging outcomes, including all-cause mortality, cancers, healthspan, physical functioning, and Alzheimer's disease...
April 18, 2018: Aging
https://www.readbyqxmd.com/read/29675547/the-association-between-fatigue-and-pain-symptoms-and-decreased-physical-activity-after-cancer
#8
Sally A D Romero, Lee Jones, Joshua M Bauml, Q Susan Li, Roger B Cohen, Jun J Mao
PURPOSE: Patients with cancer frequently experience symptoms such as fatigue and pain that can influence their ability to maintain their usual physical activity (PA). This study aimed to evaluate whether symptoms of fatigue and pain are associated with decreased PA among patients with cancer. METHODS: We recruited patients with a cancer diagnosis from one academic medical center and 11 affiliated community hospitals to participate in a cross-sectional survey. Multivariate logistic regression models were used to examine the association between symptoms, demographics, and clinical characteristics and decreased PA since cancer diagnosis...
April 19, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29675546/telehealth-applied-to-physical-activity-during-cancer-treatment-a-feasibility-acceptability-and-randomized-pilot-study
#9
Charlène Villaron, François Cury, François Eisinger, Maria-A Cappiello, Tanguy Marqueste
PURPOSE: Previous studies have underlined the benefits of exercise during cancer therapy. However, patients are insufficiently active during treatment. Telehealth is used to encourage people to be active, reducing difficulties and offsetting the lack of infrastructure often reported. We aimed to identify the effects of recommendations and telehealth on the level of physical activity, fatigue, and quality of life. METHODS: Sixty patients suffering from various cancers under treatment were randomized into two groups...
April 19, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29674317/the-atypical-mitogen-activated-protein-kinase-erk3-is-essential-for-establishment-of-epithelial-architecture
#10
Chika Takahashi, Koichi Miyatake, Morioh Kusakabe, Eisuke Nishida
Epithelia contribute to physical barriers that protect internal tissues from the external environment and also support organ structure. Accordingly, establishment and maintenance of epithelial architecture are essential for both embryonic development and adult physiology. Here, using gene knockout and -down techniques along with gene profiling, we show that extracellular signal-regulated kinase 3 (ERK3), a poorly characterized atypical mitogen-activated protein kinase (MAPK), regulates the epithelial architecture in vertebrates...
April 19, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29674230/association-of-herbal-botanic-supplement-use-with-quality-of-life-recurrence-and-survival-in-newly-diagnosed-stage-ii-colon-cancer-patients-a-2-y-follow-up-study
#11
Qiran Chen, Pengcheng Xun, Cari Lewis Tsinovoi, Beate Henschel, Alyce D Fly, Ka He
OBJECTIVES: Our objective was to investigate the association between herbal/botanic supplement use and perceived quality of life (QoL), cancer recurrence, and all-cause mortality in colon cancer patients. METHODS: Patients (n = 453) newly diagnosed with stage II adenocarcinoma of the colon between 2009 and 2011 were recruited from the North Carolina Central Cancer Registry. Data including demographic variables, herbal medicine use and frequency, lifestyle, diet, cancer treatment, and QoL were collected by interviews at diagnosis (baseline) and 1 and 2 y after diagnosis...
February 13, 2018: Nutrition
https://www.readbyqxmd.com/read/29674221/physical-activity-levels-after-treatment-for-breast-cancer-two-year-follow-up
#12
An De Groef, Inge Geraerts, Heleen Demeyer, Elien Van der Gucht, Lore Dams, Carlijn de Kinkelder, Sanne Dukers-van Althuis, Marijke Van Kampen, Nele Devoogdt
OBJECTIVES: Breast cancer treatment can have a considerable large and prolonged impact on activity levels of breast cancer survivors. Therefore, the aim of the present study was to investigate the change in total physical activity level and occupational, sport and household activity levels of breast cancer survivors from preoperatively up to 24 months after breast cancer surgery. Additionally, predictive factors for this change were investigated. METHODS: Patients with primary breast cancer (n = 267) filled in the Flemish Physical Activity Computerized Questionnaire (FPACQ) before surgery and 1, 3, 6, 12 and 24 months after surgery...
April 16, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29673836/effects-of-lifestyle-modification-on-cancer-recurrence-overall-survival-and-quality-of-life-in-gynaecological-cancer-survivors-a-systematic-review-and-meta-analysis
#13
REVIEW
Ladan Yeganeh, Cheryce Harrison, Amanda J Vincent, Helena Teede, Jacqueline A Boyle
The benefits of lifestyle interventions for women who have survived gynaecological cancer (GC) remain unclear. This systematic review aimed to determine the effect of lifestyle interventions on cancer recurrence, overall survival and quality of life (QoL) in women with GC. We searched Medline, Embase, PsycINFO and EBM Reviews from June to July 2016 to identify relevant literature. We included randomized controlled trials in which a lifestyle intervention (diet, weight loss, physical activity and/or behavioural interventions) were compared with a control condition (usual care, placebo or other lifestyle interventions) in women who had survived endometrial or ovarian cancer...
May 2018: Maturitas
https://www.readbyqxmd.com/read/29672692/physical-activity-and-cause-specific-mortality-the-rotterdam-study
#14
Chantal M Koolhaas, Klodian Dhana, Josje D Schoufour, Lies Lahousse, Frank J A van Rooij, M Arfan Ikram, Guy Brusselle, Henning Tiemeier, Oscar H Franco
Background: Physical activity (PA) is associated with lower risk for all-cause mortality. However, in elderly people, it remains unknown which types of PA are associated with mortality and whether the association between PA and mortality differs by cause of death. Methods: We assessed the association of total PA, walking, cycling, domestic work, sports and gardening with all-cause mortality, and the association of total PA with cause-specific mortality, using Cox proportional hazard models among 7225 older adults (mean age: 70 years) from the prospective population-based Rotterdam Study...
April 16, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29671528/testicular-cancer-diagnosis-and-treatment
#15
Drew C Baird, Garrett J Meyers, Jocelyn S Hu
Testicular cancer is the most common solid tumor among males 15 to 34 years of age, with an estimated 8,850 new cases and 410 deaths during 2017 in the United States. With effective treatment, the overall five-year survival rate is 97%. Risk factors for testicular cancer include undescended testis (cryptorchidism), personal or family history of testicular cancer, age, ethnicity, and infertility. The U.S. Preventive Services Task Force recommends against routine screening in asymptomatic men. Men with symptoms should receive a complete history and physical examination...
February 15, 2018: American Family Physician
https://www.readbyqxmd.com/read/29670858/health-care-professionals-perception-of-contraindications-for-physical-activity-during-cancer-treatment
#16
Angeliki Tsiouris, Nadine Ungar, Alexander Haussmann, Monika Sieverding, Karen Steindorf, Joachim Wiskemann
Introduction: Suggested medical contraindications for physical activity (PA) during cancer therapy might have an influence on PA recommendation behavior of Health Care Professionals (HCP). The purpose of the present study was to examine perceptions of physicians and oncology nurses (ON) toward specific medical conditions as contraindications for PA during cancer treatment. Materials and methods: A total of 539 physicians and 386 ON were enrolled in this cross-sectional survey...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29669735/ctgf-vegfa-activated-fibroblasts-promote-tumor-migration-through-micro-environmental-modulation
#17
Wei Wu, Esther A Zaal, Celia R Berkers, Simone Lemeer, Albert J R Heck
Fibroblast activation is associated with tumour progression and implicated in metastasis, but the initial triggering signals required to kick-start this process remain largely unknown. Since small cancerous lesions share limited physical contact with neighboring fibroblasts, we reasoned the first tumour-derived signal for fibroblast activation should be secreted and diffusible. By pulsed metabolic labeling and click-chemistry based affinity enrichment, we sieved through the ductal carcinoma secretome for potential fibroblast activators...
April 18, 2018: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/29668832/changes-in-physical-activity-behavior-and-c-reactive-protein-in-breast-cancer-patients
#18
Catherine M Sabiston, Carsten Wrosch, Andrée L Castonguay, Benjamin D Sylvester
Background: C-reactive protein (CRP) concentrations are associated with morbidity and mortality in breast cancer patients and moderate-vigorous physical activity (MVPA) may help regulate CRP levels. Purpose: The purpose of this prospective study was to examine intraindividual and interindividual changes in MVPA on changes in CRP levels among early posttreatment breast cancer patients. Methods: During five data collections over the first year posttreatment for breast cancer, women (N = 138, Mage = 55...
April 12, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29668067/social-inequality-in-cancer-survivors-health-behaviours-a-danish-population-based-study
#19
K Friis, F B Larsen, C V Nielsen, A-M H Momsen, C M Stapelfeldt
The aim of this study was to compare health behaviours (smoking, alcohol consumption, physical activity and diet), to explore social inequality in these behaviours among cancer survivors and individuals with no history of cancer, respectively, and to study the impact of time since diagnosis on cancer survivors' health behaviours. Data from the Danish National Health Survey from 2013 were linked with data from the Danish Cancer Registry to identify all cancer diagnoses among the respondents during the period 1945-2012...
April 18, 2018: European Journal of Cancer Care
https://www.readbyqxmd.com/read/29666044/capturing-ultraviolet-radiation-exposure-and-physical-activity-feasibility-study-and-comparison-between-self-reports-mobile-apps-dosimeters-and-accelerometers
#20
Elke Hacker, Caitlin Horsham, Martin Allen, Andrea Nathan, John Lowe, Monika Janda
BACKGROUND: Skin cancer is the most prevalent cancer in Australia. Skin cancer prevention programs aim to reduce sun exposure and increase sun protection behaviors. Effectiveness is usually assessed through self-report. OBJECTIVE: It was the aim of this study to test the acceptance and validity of a newly developed ultraviolet radiation (UVR) exposure app, designed to reduce the data collection burden to research participants. Physical activity data was collected because a strong focus on sun avoidance may result in unhealthy reductions in physical activity...
April 17, 2018: JMIR Research Protocols
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