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https://www.readbyqxmd.com/read/29049421/complementary-religious-and-spiritual-interventions-in-physical-health-and-quality-of-life-a-systematic-review-of-randomized-controlled-clinical-trials
#1
Juliane Piasseschi de Bernardin Gonçalves, Giancarlo Lucchetti, Paulo Rossi Menezes, Homero Vallada
OBJECTIVE: To examine whether religious and spiritual interventions (RSIs) can promote physical health and quality of life in individuals. METHODS: The following databases were used to conduct a systematic review: PubMed, Scopus, Web of Science, EMBASE, PsycINFO, Cochrane, and Scielo. Randomized controlled trials that evaluated RSIs regarding physical health outcomes and/or quality of life in English, Spanish or Portuguese were included. RSI protocols performed at a distance (i...
2017: PloS One
https://www.readbyqxmd.com/read/29049045/nutrition-physical-activity-and-lifestyle-factors-in-prostate-cancer-prevention
#2
Eric Ballon-Landa, John Kellogg Parsons
PURPOSE OF REVIEW: To review current evidence for prostate cancer prevention with nutrition, physical activity, and lifestyle interventions and identify future research directions. RECENT FINDINGS: Multiple preclinical and observational studies have observed that diet, exercise, and lifestyle interventions may play a role in mitigating disease progression, mortality, and overall disease burden for high-grade and fatal prostate cancer. Increased vegetable and fruit intakes, decreased red meat and saturated fat intakes, and increased exercise are potentially associated with decreased risk of incident disease and increased progression-free, prostate cancer-specific, and overall survival...
October 18, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/29047302/a-self-assembled-clavanin-a-coated-amniotic-membrane-scaffold-for-the-prevention-of-biofilm-formation-by-ocular-surface-fungal-pathogens
#3
Santi M Mandal, Jahangir Khan, Denial Mahata, Suman Saha, Jayangshu Sengupta, Osmar N Silva, Subhayan Das, Mahitosh Mandal, Octavio L Franco
Amniotic membrane (AM) is frequently used in ophthalmologic surgery for rapid ocular surface reconstruction. Sometimes it may create a major problem with associated infections after biofilm formation over the membrane. To overcome this problem, AM was coated with the antimicrobial peptide clavanin A. The antifungal activity of clavanin A in the native and self-assembled form was determined against the common ocular surface pathogens Candida albicans, Aspergillus fumigatus, Alternaria sp. and Fusarium sp. Biofilm formation over the coated surface was significantly reduced in comparison with the uncoated membrane...
October 19, 2017: Biofouling
https://www.readbyqxmd.com/read/29043460/longitudinal-assessment-of-the-impact-of-adapted-physical-activity-on-upper-limb-disability-and-quality-of-life-in-breast-cancer-survivors-from-an-italian-cohort
#4
Daniela Mirandola, Guido Miccinesi, Maria Grazia Muraca, Stefania Belardi, Roberta Giuggioli, Eleonora Sgambati, Mirko Manetti, Marco Monaci, Mirca Marini
PURPOSE: The purpose of this study was to evaluate the effectiveness of a specific adapted physical activity (APA) protocol on upper limb disability and quality of life in breast cancer survivors and to assess longitudinally the possible role of APA on long-term benefits. METHODS: Breast cancer survivors from an Italian cohort were assessed by fitness tests (shoulder-arm mobility, range of motion, and back flexibility) before and after 8-week APA. Quality of life and back and surgical shoulder pain intensity were evaluated by Short Form-12 and numerical rating scale questionnaires, respectively...
October 17, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29040888/physical-capability-predicts-mortality-in-late-mid-life-as-well-as-in-old-age-findings-from-a-large-british-cohort-study
#5
Victoria L Keevil, Robert Luben, Shabina Hayat, Avan A Sayer, Nicholas J Wareham, Kay-Tee Khaw
INTRODUCTION: Low physical capability predicts mortality, perhaps by association with co-morbidity. However, few studies include participants <70years old with lower co-morbidity burdens compared to older adults. We examined relationships between usual walking speed (UWS), timed chair stands speed, grip strength, standing balance and all-cause mortality in 8477 participants aged 48-92years enrolled in the European Prospective Investigation of Cancer-Norfolk study. METHODS: Participants (55...
October 4, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29040021/flexible-sigmoidoscopy-and-ct-colonography-screening-patients-experience-with-and-factors-for-undergoing-screening-insight-from-the-proteus-colon-trial
#6
Carlo Senore, Loredana Correale, Daniele Regge, Cesare Hassan, Gabriella Iussich, Marco Silvani, Arrigo Arrigoni, Lia Morra, Nereo Segnan
Purpose To compare the acceptability of computed tomographic (CT) colonography and flexible sigmoidoscopy (FS) screening and the factors predicting CT colonographic screening participation, targeting participants in a randomized screening trial. Materials and Methods Eligible individuals aged 58 years (n = 1984) living in Turin, Italy, were randomly assigned to be invited to screening for colorectal cancer with FS or CT colonography. After individuals who had died or moved away (n = 28) were excluded, 264 of 976 (27...
October 17, 2017: Radiology
https://www.readbyqxmd.com/read/29039082/metal-based-proteasomal-deubiquitinase-inhibitors-as-potential-anticancer-agents
#7
Xin Chen, Qianqian Yang, Lu Xiao, Daolin Tang, Q Ping Dou, Jinbao Liu
Deubiquitinases (DUBs) play an important role in protein quality control in eukaryotic cells due to their ability to specifically remove ubiquitin from substrate proteins. Therefore, recent findings have focused on the relevance of DUBs to cancer development, and pharmacological intervention on these enzymes has become a promising strategy for cancer therapy. In particular, several DUBs are physically and/or functionally associated with the proteasome and are attractive targets for the development of novel anticancer drugs...
October 16, 2017: Cancer Metastasis Reviews
https://www.readbyqxmd.com/read/29038181/barriers-and-facilitators-to-healthy-lifestyle-and-acceptability-of-a-dietary-and-physical-activity-intervention-among-african-caribbean-prostate-cancer-survivors-in-the-uk-a-qualitative-study
#8
Vanessa Er, J Athene Lane, Richard M Martin, Raj Persad, Frank Chinegwundoh, Victoria Njoku, Eileen Sutton
OBJECTIVES: Diet and lifestyle may have a role in delaying prostate cancer progression, but little is known about the health behaviours of Black British prostate cancer survivors despite this group having a higher prostate cancer mortality rate than their White counterparts. We explored the barriers and facilitators to dietary and lifestyle changes and the acceptability of a diet and physical activity intervention in African Caribbean prostate cancer survivors. DESIGN: We conducted semistructured in-depth interviews and used thematic analysis to code and group the data...
October 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29037604/met-activation-and-physical-dynamics-of-the-metastatic-process-the-paradigm-of-cancers-of-unknown-primary-origin
#9
REVIEW
Giulia M Stella, Silvia Benvenuti, Alessandra Gentile, Paolo M Comoglio
The molecular and cellular mechanisms which drive metastatic spread are the topic of constant debate and scientific research due to the potential implications for cancer patients' prognosis. In addition to genetics and environmental factors, mechanics of single cells and physical interaction with the surrounding environment play relevant role in defining invasive phenotype. Reconstructing the physical properties of metastatic clones may help to clarify still open issues in disease progression as well as to lead to new diagnostic and therapeutic approaches...
September 21, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29037216/exploring-the-impact-of-the-care-sport-connector-in-the-netherlands
#10
Karlijn E F Leenaars, Eva Smit, Annemarie Wagemakers, Gerard R M Molleman, Maria A Koelen
BACKGROUND: Regular physical activity (PA) is deemed to contribute to the primary and secondary prevention of several chronic diseases, like diabetes mellitus, cancer, cardiovascular diseases, and osteoporosis. In 2012, Care Sport Connectors (CSC), to whom a broker has been ascribed, were introduced in the Netherlands to stimulate PA and guide primary care patients towards local sport facilities. The aim of this study was to explore which structural embedding is the most promising for CSCs' work...
October 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29036032/a-physiological-profile-of-ovarian-cancer-survivors-to-inform-tailored-exercise-interventions-and-the-development-of-exercise-oncology-guidelines
#11
Christelle Schofield, Robert U Newton, Daniel A Galvão, Paul A Cohen, Carolyn J Peddle-McIntyre
OBJECTIVE: Physical activity has become increasingly important in supportive cancer care. However, physical activity and exercise guidelines for ovarian cancer survivors remain generic. The aim of this narrative review is to summarize existing data regarding the physiological characteristics (treatment-related adverse effects, concurrent comorbidities, body weight and composition, physical fitness and function, and physical activity behavior) of ovarian cancer survivors to further understanding of their cancer-specific physical activity and exercise needs...
September 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29035739/physical-oncology-new-targets-for-nanomedicine
#12
REVIEW
Alba Nicolas-Boluda, Amanda K A Silva, Sylvie Fournel, Florence Gazeau
Physical oncology is an emerging paradigm which recognizes tissue mechanics, per se, as an active modulator of tumorigenesis, treatment resistance and clinical outcome, mediated by mechanosignaling pathways, matrix remodeling and physical barriers to drugs. The tumor microenvironment displays abnormal physical properties in comparison to healthy tissue which contribute to cancer progression and resistance to current treatments. Physical aberrancies comprise the chaotic organization of tumor vasculature, an increased interstitial pressure, an increased solid stress, hypoxia, an abundant extracellular matrix and a progressive stiffening of solid tumors...
October 6, 2017: Biomaterials
https://www.readbyqxmd.com/read/29035603/competition-level-not-associated-with-diet-quality-in-marching-artists
#13
Colleen R McConnell, Alyssa McPherson, Kathleen Woolf
Marching artists are a unique group of athletes whose performance can be influenced by nutrition. Because physical demands are thought to be moderate to high, adequate energy and a variety of nutrient-dense foods are needed. The purpose of this study was to examine diet quality, physical activity, and eating behavior of marching artists across elite and non-elite competition levels. This cross-sectional analysis used the validated National Cancer Institute Diet History Questionnaire II, International Physical Activity Questionnaire, and Eating Behavior Patterns Questionnaire...
October 16, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29033590/sitting-time-and-occupational-and-recreational-physical-activity-in-relation-to-the-risk-of-esophageal-squamous-cell-carcinoma
#14
Pengxiang Chen, Qingxu Song, Jie Han, Huapu Xu, Tong Chen, Jiaqi Xu, Yufeng Cheng
BACKGROUNDS: Sitting time and physical activity are associated with cancer risk; however, their roles in the development of esophageal squamous cell carcinoma (ESCC) are inconclusive. This study aimed to investigate the effects of total sitting time, occupational activity time (OAT), and recreational activity time (RAT) on ESCC risk. METHODS: Five hundred fifty-seven ESCC patients and 543 healthy controls matched by sex and age were recruited for this study. Conditional logistic regression was performed to obtain odds ratios (ORs) and 95% confidence intervals (CIs)...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29030414/longitudinal-associations-between-marine-omega-3-supplement-users-and-coronary-heart-disease-in-a-uk-population-based-cohort
#15
Marleen A H Lentjes, Ruth H Keogh, Ailsa A Welch, Angela A Mulligan, Robert N Luben, Nicholas J Wareham, Kay-Tee Khaw
OBJECTIVES: Assess the association between marine omega-3 polyunsaturated fatty acid (n-3 PUFA) intake from supplements, mainly cod liver oil, and coronary heart disease (CHD) mortality. DESIGN: Prospective cohort study, with three exposure measurements over 22 years. SETTING: Norfolk-based European Prospective Investigation into Cancer (EPIC-Norfolk, UK). PARTICIPANTS: 22 035 men and women from the general population, 39-79 years at recruitment...
October 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/29027602/combining-risk-communication-strategies-to-simultaneously-convey-the-risks-of-four-diseases-associated-with-physical-inactivity-to-socio-demographically-diverse-populations
#16
Eva Janssen, Robert A C Ruiter, Erika A Waters
A single risk factor can increase the risk of developing multiple diseases, but most risk communication research has been conducted in the context of a single disease. We explored which combination of three recommended risk communication strategies is most effective in simultaneously conveying risk estimates of four diseases associated with physical inactivity: colon cancer, stroke, diabetes, and heart disease. Participants (N = 1161, 50% no college experience, 50% racial/ethnic minority) were shown hypothetical risk estimates for each of the four diseases...
October 13, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29025675/acetal-linked-pegylated-paclitaxel-prodrugs-forming-free-paclitaxel-loaded-ph-responsive-micelles-with-high-drug-loading-capacity-and-improved-drug-delivery
#17
Da Huang, Yaping Zhuang, Hong Shen, Fei Yang, Xing Wang, Decheng Wu
Endosomal pH-responsive micellar nanoparticles were prepared by self-assembly of an amphiphilic poly(ethylene glycol)-acetal-paclitaxel (PEG-acetal-PTX) prodrug, and free PTX could be encapsulated in the hydrophobic core of the nanoparticles. These nanoparticles exhibited excellent storage stability for over 6months under normal conditions, but disassembled quickly in response to faintly acidic environment. Incorporating physical encapsulation and chemical conjugation, the PTX concentration in the nanoparticles solution could reach as high as 3665μg/mL, accompanying with a high drug loading capacity of 60...
January 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29025645/enhancing-the-anti-gastric-cancer-activity-of-curcumin-with-biocompatible-and-ph-sensitive-pmma-aa-zno-nanoparticles
#18
Raman Dhivya, Jothi Ranjani, Jeyaprakash Rajendhran, Jeyanthinath Mayandi, Jamespandi Annaraj
Curcumin loaded ZnO nanoparticles were successfully synthesised and encapsulated with co-polymer PMMA-AA (Cur/PMMA-AA/ZnO NPs). The ZnO nanoparticles have been converted as good cargo materials to carry the well-known hydrophobic drug curcumin by surface functionalization. Physical characteristics of these novel nanomaterials have been studied with transmission electron microscopy (TEM) and powder X-ray diffraction (XRD) in conjunction with spectral techniques. A narrow particle size distribution with an average value of 42nm was found via TEM...
January 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29025506/maintenance-of-lifestyle-changes-at-12-month-follow-up-in-a-nutrition-and-physical-activity-trial-for-cancer-survivors
#19
Fiona G Stacey, David R Lubans, Kathy Chapman, Alessandra Bisquera, Erica L James
OBJECTIVES: In this paper, we report maintenance of behavior change in a nutrition and physical activity intervention for cancer survivors at 12-months follow-up. METHODS: The ENRICH (Exercise and Nutrition Routine Improving Cancer Health) program was an 8-week face-to-face program for cancer survivors and caregivers, focused on healthy eating, healthy weight, resistance training, and a walking program. Randomized controlled trial participants completed a survey and 7-days of pedometry at baseline, 8-weeks, and 20-weeks...
November 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29025130/domain-specific-physical-activity-and-sedentary-behaviour-in-relation-to-colon-and-rectal-cancer-risk-a-systematic-review-and-meta-analysis
#20
Shahid Mahmood, Robert J MacInnis, Dallas R English, Amalia Karahalios, Brigid M Lynch
Background: Physical activity is associated with reduced risk of colorectal cancer, but most epidemiological studies have focused on occupational and recreational physical activity. The evidence for other domains of activity, and for sedentary behaviour, is limited. Methods: Medline, Embase and Web of Science were searched from inception to December 2015 for studies examining domain-specific physical activity or sedentary behaviour and the risk of colon and/or rectal cancer...
August 25, 2017: International Journal of Epidemiology
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