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Physical activity cancer

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https://www.readbyqxmd.com/read/28432494/primary-prevention-and-screening-practices-among-long-term-breast-cancer-survivors
#1
Lori Mandelzweig, Angela Chetrit, Tova Amitai, Barbara Silverman, Nava Siegelmann-Danieli, Siegal Sadetzki
PURPOSE: Parallel to increasing survival of breast cancer (BC) patients, a need has arisen to characterize the follow-up required to improve and maintain their health. Our study aimed to assess changes in lifestyle habits over time among the study population, compare compliance rates of selected primary and secondary prevention practices between long-term BC survivors and an age-matched comparison group, and identify factors associated with compliance to these practices. METHODS: The study population comprised 250 Israeli BC survivors, diagnosed with BC between 1999 and 2003, without evidence of disease after 8-12 years, and 250 women with no cancer history, individually matched to survivors by age and area of residence...
April 21, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28431509/regular-recreational-physical-activity-and-risk-of-head-and-neck-cancer
#2
Chen-Lin Lin, Wei-Ting Lee, Chun-Yen Ou, Jenn-Ren Hsiao, Cheng-Chih Huang, Jehn-Shyun Huang, Tung-Yiu Wong, Ken-Chung Chen, Sen-Tien Tsai, Sheen-Yie Fang, Tze-Ta Huang, Jiunn-Liang Wu, Yuan-Hua Wu, Wei-Ting Hsueh, Chia-Jui Yen, Yu-Hsuan Lai, Hsiao-Chen Liao, Shang-Yin Wu, Ming-Wei Yang, Forn-Chia Lin, Jang-Yang Chang, Yi-Hui Wang, Ya-Ling Weng, Han-Chien Yang, Yu-Shan Chen, Jeffrey S Chang
BACKGROUND: Although substantial evidence supports a 20-30% risk reduction of colon cancer, breast cancer, and endometrial cancer by physical activity (PA), the evidence for head and neck cancer (HNC) is limited. Three published studies on the association between PA and HNC have generated inconsistent results. The current study examined the association between recreational PA (RPA) and HNC risk with a more detailed assessment on the intensity, frequency, duration, and total years of RPA...
April 21, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28431396/skeletal-muscle-measures-and-physical-function-in-older-adults-with-cancer-sarcopenia-or-myopenia
#3
Grant R Williams, Allison M Deal, Hyman B Muss, Marc S Weinberg, Hanna K Sanoff, Kirsten A Nyrop, Mackenzi Pergolotti, Shlomit Strulov Shachar
BACKGROUND: Skeletal muscle loss, commonly known as sarcopenia, is highly prevalent in older adults and linked with adverse outcomes in cancer, yet the definition and role of sarcopenia remains uncertain. The aim of this study was to examine the association of Computerized Tomography (CT) assessed skeletal muscle measures with physical function in older adults with cancer. RESULTS: CTs for 185 patients were available. Median age 73 (IQR 68-76) and 56.5% female. After controlling for sex and BMI, we found no evidence that SMI was associated with physical function impairments...
April 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28431250/nuclear-proximity-of-mtr4-to-rna-exosome-restricts-dna-mutational-asymmetry
#4
Junghyun Lim, Pankaj Kumar Giri, David Kazadi, Brice Laffleur, Wanwei Zhang, Veronika Grinstein, Evangelos Pefanis, Lewis M Brown, Erik Ladewig, Ophélie Martin, Yuling Chen, Raul Rabadan, François Boyer, Gerson Rothschild, Michel Cogné, Eric Pinaud, Haiteng Deng, Uttiya Basu
The distribution of sense and antisense strand DNA mutations on transcribed duplex DNA contributes to the development of immune and neural systems along with the progression of cancer. Because developmentally matured B cells undergo biologically programmed strand-specific DNA mutagenesis at focal DNA/RNA hybrid structures, they make a convenient system to investigate strand-specific mutagenesis mechanisms. We demonstrate that the sense and antisense strand DNA mutagenesis at the immunoglobulin heavy chain locus and some other regions of the B cell genome depends upon localized RNA processing protein complex formation in the nucleus...
April 20, 2017: Cell
https://www.readbyqxmd.com/read/28430009/evaluating-questionnaires-used-to-assess-self-reported-physical-activity-and-psychosocial-outcomes-among-survivors-of-adolescent-and-young-adult-cancer-a-cognitive-interview-study
#5
Amanda Wurz, Jennifer Brunet
Physical activity is increasingly being studied as a way to improve psychosocial outcomes (e.g., quality of life, self-efficacy, physical self-perceptions, self-esteem, body image, posttraumatic growth) among survivors of adolescent and young adult (AYA) cancer. Assessing levels of and associations between self-reported physical activity and psychosocial outcomes requires clear, appropriate, and relevant questionnaires. To explore how survivors of AYA cancer interpreted and responded to the following eight published questionnaires: Leisure Time Exercise Questionnaire, Exercise Self-Efficacy Scale, Physical Self-Description Questionnaire, Rosenberg Global Self-Esteem Scale, Multidimensional Body-Self Relations Questionnaire, Posttraumatic Growth Inventory, Functional Assessment of Cancer Therapy-General (FACT-G), RAND 36-Item Health Survey 1...
April 21, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28428881/nano-pulse-stimulation-is-a-physical-modality-that-can-trigger-immunogenic-tumor-cell-death
#6
Richard Nuccitelli, Amanda McDaniel, Snjezana Anand, John Cha, Zachary Mallon, Jon Casey Berridge, Darrin Uecker
BACKGROUND: We have been developing a non-thermal, drug-free tumor therapy called Nano-Pulse Stimulation (NPS) that delivers ultrashort electric pulses to tumor cells which eliminates the tumor and inhibits secondary tumor growth. We hypothesized that the mechanism for inhibiting secondary tumor growth involves stimulating an adaptive immune response via an immunogenic form of apoptosis, commonly known as immunogenic cell death (ICD). ICD is characterized by the emission of danger-associated molecular patterns (DAMPs) that serve to recruit immune cells to the site of the tumor...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28428732/access-to-information-and-counselling-older-cancer-patients-self-report-a-cross-sectional-survey
#7
Kristin Vassbotn Guldhav, Randi Jepsen, Siri Ytrehus, Ellen Karine Grov
BACKGROUND: An increasingly older population, improved diagnostics and treatment increase the number of older cancer survivors, thus more than 60% of those affected by cancer are over the age of 65. Symptom relief and the prevention of functional impairment are important tasks for home care nursing, considering that patients can live a long time with their cancer disease and related side effects. The aim of this study was to investigate the extent to which cancer patients over the age of 65 reported access to information and counselling from home care nursing services, including those offered by the cancer coordinator...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28428170/who-uses-mobile-phone-health-apps-and-does-use-matter-a-secondary-data-analytics-approach
#8
Jennifer K Carroll, Anne Moorhead, Raymond Bond, William G LeBlanc, Robert J Petrella, Kevin Fiscella
BACKGROUND: Mobile phone use and the adoption of healthy lifestyle software apps ("health apps") are rapidly proliferating. There is limited information on the users of health apps in terms of their social demographic and health characteristics, intentions to change, and actual health behaviors. OBJECTIVE: The objectives of our study were to (1) to describe the sociodemographic characteristics associated with health app use in a recent US nationally representative sample; (2) to assess the attitudinal and behavioral predictors of the use of health apps for health promotion; and (3) to examine the association between the use of health-related apps and meeting the recommended guidelines for fruit and vegetable intake and physical activity...
April 19, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28427925/effect-of-home-and-community-based-physical-activity-interventions-on-physical-function-among-cancer-survivors-a-systematic-review-and-meta-analysis
#9
REVIEW
Maria C Swartz, Zakkoyya H Lewis, Elizabeth J Lyons, Kristofer Jennings, Addie Middleton, Rachel R Deer, Demi Arnold, Kaitlin Dresser, Kenneth J Ottenbacher, James S Goodwin
OBJECTIVE: We reviewed randomized trials to examine the effect of home and community-based physical activity interventions on physical functioning among cancer survivors based on the most prevalent physical function measures. DATA SOURCES: Five electronic databases-Medline Ovid, Pubmed, CINAHL, Web of Science, and PsychINFO-were searched from inception to March 2016 for relevant articles. STUDY SELECTION: Search terms included: community-based interventions, physical functioning, and cancer survivors...
April 17, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28427834/doped-silica-fibre-thermoluminescence-measurements-of-radiation-dose-in-the-use-of-223-ra
#10
Bradley, S F Abdul Sani, A S Siti Shafiqah, S M Collins, R P Hugtenburg, H A Abdul Rashid, Nurul Najua Zulkepely, M J Maah
Using tailor-made sub-mm dimension doped-silica fibres, thermoluminescent dosimetric studies have been performed for α-emitting sources of (223)RaCl2 (the basis of the Bayer Healthcare product Xofigo®). The use of (223)RaCl2 in the palliative treatment of bone metastases resulting from late-stage castration-resistant prostate cancer focuses on its favourable uptake in metabolically active bone metastases. Such treatment benefits from the high linear energy transfer (LET) and associated short path length (<100µm) of the α-particles emitted by (223)Ra and its decay progeny...
April 14, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28427084/long-term-improvement-of-breast-cancer-survivors-quality-of-life-by-a-2-week-group-physical-and-educational-intervention-5-year-update-of-the-pacthe-trial
#11
Fabrice Kwiatkowski, Marie-Ange Mouret-Reynier, Martine Duclos, François Bridon, Thierry Hanh, Isabelle Van Praagh-Doreau, Armelle Travade, Marie-Paule Vasson, Sylvie Jouvency, Christian Roques, Yves-Jean Bignon
BACKGROUND: The advantages of adapted physical activity and nutritional education (APANE) on breast cancer prognosis and quality of life (QoL) are well known, but long-term results are lacking. METHODS: A randomised controlled trial testing a 2-week intervention in hydrothermal centres including APANE enrolled 251 patients post-chemotherapy. QoL and weight control were significantly improved at 12 months. A 5-year follow-up was performed to evaluate the persistence of improvements...
April 20, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28423225/exercise-interventions-for-patients-with-pediatric-cancer-during-inpatient-acute-care-a-systematic-review-of-literature
#12
REVIEW
Vanessa Rustler, Meaghan Hagerty, Julia Daeggelmann, Stacey Marjerrison, Wilhelm Bloch, Freerk T Baumann
Physical inactivity has been shown to exacerbate negative side effects experienced by pediatric patients undergoing cancer therapy. Exercise interventions are being created in response. This review summarizes current exercise intervention data in the inpatient pediatric oncology setting. Two independent reviewers collected literature from three databases, and analyzed data following the PRISMA statement for systematic reviews and meta-analyses. Ten studies were included, representing 204 patients. Good adherence, positive trends in health status, and no adverse events were noted...
April 19, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28422585/validation-of-the-ipaq-against-different-accelerometer-cut-points-in-older-cancer-survivors-and-adults-at-risk-of-cancer
#13
Liane S Lewis, James Hernon, Allan Clark, John M Saxton
INTRODUCTION: The present study investigated the convergent validity of an interview-administered IPAQ long version (IPAQ-L) in an older population by comparison with objective accelerometry movement data. METHODS: Data from 52 participants (mean age 67.9 years, 62% male) were included in the analysis. Treadmill derived (TM-ACC: 1952-5724 cpm) and free-living physical activity (PA) derived (FL-ACC: 760-5724 cpm) accelerometer cut-points were used as criterion. RESULTS: IPAQ-L measures (total PA, leisure-time, walking-time, sedentary time) were significantly correlated with accelerometry (P≤0...
April 19, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/28420602/the-fitbit-one-physical-activity-tracker-in-men-with-prostate-cancer-validation-study
#14
Erin L Van Blarigan, Stacey A Kenfield, Lucy Tantum, Lisa A Cadmus-Bertram, Peter R Carroll, June M Chan
BACKGROUND: Physical activity after cancer diagnosis improves quality of life and may lengthen survival. However, objective data in cancer survivors are limited and no physical activity tracker has been validated for use in this population. OBJECTIVE: The aim of this study was to validate the Fitbit One's measures of physical activity over 7 days in free-living men with localized prostate cancer. METHODS: We validated the Fitbit One against the gold-standard ActiGraph GT3X+ accelerometer in 22 prostate cancer survivors under free-living conditions for 7 days...
April 18, 2017: JMIR Cancer
https://www.readbyqxmd.com/read/28419714/young-people-s-beliefs-about-the-risk-of-bowel-cancer-and-its-link-with-physical-activity
#15
Katie V Newby, Chloe Cook, Susanne F Meisel, Thomas L Webb, Bernadette Fisher, Abi Fisher
OBJECTIVES: The primary objective was to explore young people's risk appraisals of bowel cancer, including whether they had a coherent understanding of the protective effects of physical activity (PA). A secondary objective was to examine whether the illness risk representations (IRRs) framework could be used to understand beliefs underlying bowel cancer risk appraisals. DESIGN: Qualitative. METHODS: Framework analysis of semi-structured interviews with 19 people aged 14-17 years...
April 17, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28418750/comparing-asian-american-women-s-knowledge-self-efficacy-and-perceived-risk-of-heart-attack-to-other-racial-and-ethnic-groups-the-mped-trial
#16
Yoshimi Fukuoka, Nadra E Lisha, Eric Vittinghoff
OBJECTIVE: The aim of the study was to compare knowledge and awareness of heart attacks/heart disease and perceived risk for future heart attack in Asian/Pacific Islander women, compared to other racial and ethnic groups. MATERIALS AND METHODS: In this cross-sectional study, 318 women enrolled in a mobile phone-based physical activity education trial were analyzed. Heart attack knowledge, self-efficacy for recognizing and responding to heart attack symptoms, and perceived risk for a future heart attack were measured...
April 18, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28417243/criterion-related-validity-of-self-reported-stair-climbing-in-older-adults
#17
Sara Higueras-Fresnillo, Irene Esteban-Cornejo, Pablo Gasque, Oscar L Veiga, David Martinez-Gomez
INTRODUCTION: Stair climbing is an activity of daily living that might contribute to increase levels of physical activity (PA). To date, there is no study examining the validity of climbing stairs assessed by self-report. The aim of this study was, therefore, to examine the validity of estimated stair climbing from one question included in a common questionnaire compared to a pattern-recognition activity monitor in older adults. METHODS: A total of 138 older adults (94 women), aged 65-86 years (70...
April 17, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28415691/a-potentially-functional-variant-of-arid1b-interacts-with-physical-activity-in-association-with-risk-of-hepatocellular-carcinoma
#18
Li Liu, Nana Tian, Chengyu Zhou, Xinqi Lin, Weibiao Lv, Zhifeng Lin, Zibo Lin, Yongfen Qi, Yi Yang, Sidong Chen, Xinfa Yu, Yanhui Gao
The tumor suppressor role of AT-rich interactive domain containing protein 1B (ARID1B) has drawn much attention in area of cancer etiology. However, it had remained unknown whether or not genetic variants of ARID1B involved in development of hepatocellular carcinoma (HCC). In this study, three putatively functional variants in ARID1B (rs73013281C>T, rs167007A>G, and rs9397984C>T) were selected using bioinformatics tools, and a case-control study of 611 cases and 614 controls was conducted to investigate genetic associations with HCC risk in a Southern Chinese population...
March 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415044/long-non-coding-rna-snhg1-regulates-zinc-finger-e-box-binding-homeobox-1-expression-by-interacting-with-tap63-and-promotes-cell-metastasis-and-invasion-in-lung-squamous-cell-carcinoma
#19
Hong-Yan Zhang, Wei Yang, Fu-Shuang Zheng, Yi-Bei Wang, Ji-Bin Lu
The long non-coding RNAs (lncRNAs) have been recently shown to participate in the progression of a variety of cancers. However, the biological role of lncRNAs and the underlying mechanisms in Lung squamous cell carcinoma (SCC) or lung adenocarcinoma (AD) remain unclear. Herein, we investigated expression of 5 lncRNAS (SNHG1, NCBP2-AS2, LINC01206, SOX2-OT and LINC01419) in SCC and AD tissues. SNHG1 was one of over-expressed lncRNAs in SCC tissues. Knockdown of SNHG1 significantly inhibited the proliferation, metastasis, invasive ability and induced apoptosis of SCC cells...
April 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28415013/the-effect-of-exercise-on-fatigue-and-physical-functioning-in-breast-cancer-patients-during-and-after-treatment-and-at-6-months-follow-up-a-meta-analysis
#20
REVIEW
L K Juvet, I Thune, I K Ø Elvsaas, E A Fors, S Lundgren, G Bertheussen, G Leivseth, L M Oldervoll
Breast cancer is the leading cause of cancer in women worldwide. Exercise interventions may improve physical and psychological factors during and after active breast cancer treatment. The aim of this systematic review was to assess the current knowledge regarding the efficacy of physical exercise with respect to fatigue and self-reported physical functioning. Systematic searches in Cochrane Library, Medline, Embase, Cinahl, PsycINFO, AMED and PEDro. After assessing the quality of the studies, we identified 25 randomized controlled trials that included 3418 breast cancer patients...
April 14, 2017: Breast: Official Journal of the European Society of Mastology
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