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https://www.readbyqxmd.com/read/28327655/thin-film-metallic-glass-an-effective-diffusion-barrier-for-se-doped-agsbte2-thermoelectric-modules
#1
Chia-Chi Yu, Hsin-Jay Wu, Ping-Yuan Deng, Matthias T Agne, G Jeffrey Snyder, Jinn P Chu
The thermal stability of joints in thermoelectric (TE) modules, which are degraded during interdiffusion between the TE material and the contacting metal, needs to be addressed in order to utilize TE technology for competitive, sustainable energy applications. Herein, we deposit a 200 nm-thick Zr-based thin-film metallic glass (TFMG), which acts as an effective diffusion barrier layer with low electrical contact resistivity, on a high-zT Se-doped AgSbTe2 substrate. The reaction couples structured with TFMG/TE are annealed at 673 K for 8-360 hours and analyzed by electron microscopy...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327592/anisotropy-of-hydrogen-diffusion-in-nickel-single-crystals-the-effects-of-self-stress-and-hydrogen-concentration-on-diffusion
#2
J Li, A Oudriss, A Metsue, J Bouhattate, X Feaugas
Hydrogen diffusion has an important role in solute-dependent hydrogen embrittlement in metals and metallic alloys. In spite of extensive studies, the complexity of hydrogen diffusion in solids remains a phenomenon that needs to be clarified. In this paper, we investigate the anisotropy of hydrogen diffusion in pure nickel single crystals using both an experimental approach and a thermodynamic development. As a first approximation, experimental data from electrochemical permeation and thermal desorption spectroscopy are described using the classical Fick's laws and an apparent diffusion tensor...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28323766/-zero-preventable-deaths-and-minimizing-disability-the-challenge-set-forth-by-the-national-academies-of-sciences-engineering-and-medicine
#3
Daniel J Stinner, Anthony E Johnson, Andrew Pollak, Ellen MacKenzie, James R Ficke, Robert L Mabry, James Czarnik, Andrew Schmidt
No abstract text is available yet for this article.
April 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28315943/hyperoxia-reduces-oxygen-consumption-in-children-with-pulmonary-hypertension
#4
Long Guo, Prashant Bobhate, Shine Kumar, Karunakar Vadlamudi, Tarek Kaddoura, Mohamed Elgendi, Paula Holinski, James Y Coe, Jennifer Rutledge, Ian Adatia
High inspired oxygen concentration (FiO2 > 0.85) is administered to test pulmonary vascular reactivity in children with pulmonary hypertension (PH). It is difficult to measure oxygen consumption (VO2) if the subject is breathing a hyperoxic gas mixture so the assumption is made that baseline VO2 does not change. We hypothesized that hyperoxia changes VO2. We sought to compare the VO2 measured by a thermodilution catheter in room air and hyperoxia. A retrospective review of the hemodynamic data obtained in children with PH who underwent cardiac catheterization was conducted between 2009 and 2014...
March 18, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28291446/military-and-civilian-collaboration-the-power-of-numbers
#5
Daniel J Stinner, Joseph C Wenke, James R Ficke, Wade Gordon, James Toledano, Anthony R Carlini, Daniel O Scharfstein, Ellen J MacKenzie, Michael J Bosse, Joseph R Hsu
The purpose of this study was to compare the number and types of extremity injuries treated at civilian trauma centers (CIV CENs) versus military treatment facilities (MTFs) participating in the Major Extremity Trauma Research Consortium (METRC) and to investigate the potential benefits of a clinical research network that includes both civilian trauma centers and MTFs. Two analyses were performed. First, registry data collected on all surgically treated fractures at four core MTFs and 21 CIV CENs over one year were compared...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28288311/screening-of-biocides-metals-and-antibiotics-in-swedish-sewage-sludge-and-wastewater
#6
Marcus Östman, Richard H Lindberg, Jerker Fick, Erik Björn, Mats Tysklind
Incoming sewage water, treated effluent and digested sludge were collected from 11 Swedish sewage treatment plants (STPs) on 3 different days. Analytical protocols were established for a large number of compounds (47) with antimicrobial properties and the collected samples were then screened for the presence of these selected substances. Liquid chromatography tandem mass spectrometry (LC-MS/MS) and inductively coupled plasma mass spectrometry (ICP-MS) were used to analyse the samples. Thirty organic compounds and 10 metals were detected above their respective detection limit...
March 6, 2017: Water Research
https://www.readbyqxmd.com/read/28273540/screening-of-benzodiazepines-in-thirty-european-rivers
#7
Jerker Fick, Tomas Brodin, Martina Heynen, Jonatan Klaminder, Micael Jonsson, Katerina Grabicova, Tomas Randak, Roman Grabic, Vit Kodes, Jaroslav Slobodnik, Andrew Sweetman, Mark Earnshaw, Anna Barra Caracciolo, Teresa Lettieri, Robert Loos
Pharmaceuticals as environmental contaminants have received a lot of interest over the past decade but, for several pharmaceuticals, relatively little is known about their occurrence in European surface waters. Benzodiazepines, a class of pharmaceuticals with anxiolytic properties, have received interest due to their behavioral modifying effect on exposed biota. In this study, our results show the presence of one or more benzodiazepine(s) in 86% of the analyzed surface water samples (n = 138) from 30 rivers, representing seven larger European catchments...
February 27, 2017: Chemosphere
https://www.readbyqxmd.com/read/28249804/hypothesis-why-%C3%AE-no-could-be-finite-in-vitro-but-infinite-in-vivo
#8
Colin Borland, Suhani Patel, Qingyu Zhu, Alain Vuylsteke
There is controversy as to whether the lung Diffusing Capacity for Nitric Oxide (DLNO) is a direct measure of DM in the Roughton-Forster equation or whether θNO is finite and DM is greater than DLNO. Despite in vitro evidence that θNO is finite, some groups believe that it is infinite in vivo and that DMNO/DMCO (α) is greater than predicted by the combined Fick/Graham law of Gas Diffusion through a membrane. We here present a hypothesis applying the fundamental rules of combined diffusion and chemical reaction to a red cell to explain (i) why θNO could be finite in vitro but effectively infinite in vivo and (ii) why ∝ could appear greater than predicted...
February 26, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28221379/bridgehead-isomer-effects-in-bis-phosphido-bridged-diiron-hexacarbonyl-proton-reduction-electrocatalysts
#9
Ahibur Rahaman, Carolina Gimbert-Suriñach, Arne Ficks, Graham E Ball, Mohan Bhadbhade, Matti Haukka, Lee Higham, Ebbe Nordlander, Stephen B Colbran
The influence of the substitution, orientation and structure of the phosphido bridges in [Fe2(CO)6(μ-PR2)2] electrocatalysts of proton reduction has been studied. The isomers e,a-[Fe2(CO)6{μ-P(Ar)H}2] (1a(Ar): Ar = Ph, 2'-methoxy-1,1'-binaphthyl (bn')), e,e-[Fe2(CO)6{μ-P(Ar)H}2] (1b(Ar): Ar = Ph, bn') were isolated from reactions of iron pentacarbonyl and the corresponding primary phosphine, syntheses that also afforded the phosphinidene-capped tri-iron clusters, [Fe3(CO)9(μ-CO)(μ3-Pbn')] (2) and [Fe3(CO)9(μ3-PAr)2] (3(Ar), Ar = Ph, bn')...
February 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28209349/frequency-of-and-significance-of-physical-frailty-in-patients-with-heart-failure
#10
Quin E Denfeld, Kerri Winters-Stone, James O Mudd, Shirin O Hiatt, Christopher V Chien, Christopher S Lee
Physical frailty is an important prognostic indicator in heart failure (HF); however, few studies have examined the relation between physical frailty and invasive hemodynamics among adults with HF. The purpose of this study was to characterize physical frailty in HF in relation to invasive hemodynamics. We enrolled 49 patients with New York Heart Association class II to IV HF when participants were scheduled for a right-sided cardiac heart catheterization procedure. Physical frailty was measured according to the "frailty phenotype": shrinking, weakness, slowness, physical exhaustion, and low physical activity...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28207478/-zero-preventable-deaths-and-minimizing-disability-the-challenge-set-forth-by-the-national-academies-of-sciences-engineering-and-medicine
#11
Daniel J Stinner, Anthony E Johnson, Andrew Pollak, Ellen MacKenzie, James R Ficke, Robert L Mabry, James Czarnik, Andrew Schmidt
No abstract text is available yet for this article.
February 15, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28203124/when-diarrhea-can-become-deadly-legionnaires-disease-complicated-by-bowel-obstruction
#12
Wesley Prichard, Laurel Fick
Legionnaires' disease may present with a broad spectrum of illnesses and nonspecific extrapulmonary symptoms including diarrhea. To our knowledge, bowel obstruction has not been reported as a manifestation of Legionella. We present a unique case of Legionnaires' disease contributing to a small bowel obstruction.
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28191357/metastatic-invasive-lobular-breast-cancer-presenting-clinically-with-esophageal-dysphagia
#13
Lilit Karapetyan, Heather Laird-Fick, Reuben Cuison
Background. Intra-abdominal metastases of invasive lobular breast cancer (ILBC) may be insidious. We report a case of metastatic ILBC that presented with dysphagia within weeks of a negative mammogram and before the development of intra-abdominal symptoms. Case. A 70-year-old female developed esophageal dysphagia. She underwent EGD which showed a short segment of stricture of the distal esophagus without significant mucosal changes. Biopsy was unremarkable and patient underwent lower esophageal sphincter (LES) dilation...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/28187374/the-strengths-and-weaknesses-of-non-invasive-parameters-obtained-by-echocardiography-and-cardiopulmonary-exercise-testing-in-comparison-with-the-hemodynamic-assessment-by-the-right-heart-catheterization-in-patients-with-pulmonary-hypertension
#14
Katarzyna Ptaszyńska-Kopczyńska, Anna Krentowska, Emilia Sawicka, Anna Skoneczny, Małgorzata Jasiewicz, Małgorzata Knapp, Włodzimierz J Musiał, Bożena Sobkowicz, Karol A Kamiński
PURPOSE: Pulmonary hypertension (PH) diagnosis requires invasive assessment by right heart catheterization (RHC), but screening and monitoring are performed using non-invasive methods: echocardiography and cardiopulmonary exercise testing (CPET). The aim of the study was to assess correlations between the parameters obtained in non-invasive testing and RHC in patients with PH of different etiologies. MATERIAL/METHODS: The study included 53 medical records of PH patients (32 women) aged 29-81 years...
June 14, 2016: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28185701/immediate-increase-of-cardiac-output-after-percutaneous-mitral-valve-repair-pmvr-determined-by-echocardiographic-and-invasive-parameters-patzelt-increase-of-cardiac-output-after-pmvr
#15
Johannes Patzelt, Yingying Zhang, Harry Magunia, Rezo Jorbenadze, Michal Droppa, Miriam Ulrich, Shanglang Cai, Henning Lausberg, Tobias Walker, Tobias Wengenmayer, Peter Rosenberger, Juergen Schreieck, Peter Seizer, Meinrad Gawaz, Harald F Langer
BACKGROUND: Successful percutaneous mitral valve repair (PMVR) in patients with severe mitral regurgitation (MR) causes changes in hemodynamics. Echocardiographic calculation of cardiac output (CO) has not been evaluated in the setting of PMVR, so far. Here we evaluated hemodynamics before and after PMVR with the MitraClip system using pulmonary artery catheterization, transthoracic (TTE) and transesophageal (TEE) echocardiography. METHODS: 101 patients with severe MR not eligible for conventional surgery underwent PMVR...
January 26, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28178841/diffusion-dominated-evaporation-in-multicomponent-lattice-boltzmann-simulations
#16
Dennis Hessling, Qingguang Xie, Jens Harting
We present a diffusion dominated evaporation model using the popular pseudopotential multicomponent lattice Boltzmann method introduced by Shan and Chen. With an analytical computation of the diffusion coefficients, we demonstrate that Fick's law is obeyed. We then validate the applicability of our model by demonstrating the agreement of the time evolution of the interface position of an evaporating planar film to the analytical prediction. Furthermore, we study the evaporation of a freely floating droplet and confirm that the effect of Laplace pressure is significant for predicting the time evolution of small droplet radii...
February 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28174344/glucagon-like-peptide-1-elicits-vasodilation-in-adipose-tissue-and-skeletal-muscle-in-healthy-men
#17
Ali Asmar, Meena Asmar, Lene Simonsen, Sten Madsbad, Jens J Holst, Bolette Hartmann, Charlotte M Sorensen, Jens Bülow
In healthy subjects, we recently demonstrated that during acute administration of GLP-1, cardiac output increased significantly, whereas renal blood flow remained constant. We therefore hypothesize that GLP-1 induces vasodilation in other organs, for example, adipose tissue, skeletal muscle, and/or splanchnic tissues. Nine healthy men were examined twice in random order during a 2-hour infusion of either GLP-1 (1.5 pmol kg(-1) min(-1)) or saline. Cardiac output was continuously estimated noninvasively concomitantly with measurement of intra-arterial blood pressure...
February 2017: Physiological Reports
https://www.readbyqxmd.com/read/28165803/tanshinol-sustained-release-pellets-with-absorption-enhancer-optimization-characterization-pharmacokinetics-and-pharmacodynamics
#18
Panpan Yu, Shuangshuang Zhang, Wenli Zhang, Jikun Yang, Jing Lu, Jianping Liu
The objective of this study was to develop tanshinol sustained-release pellets (TS-SRPs) for the treatment of angina. Considering the poor intestinal absorption of TS, sodium caprate (SC) was used as an absorption enhancer for bioavailability improvement. Single-pass intestinal perfusion in rats demonstrated that the permeability of TS was remarkably enhanced, when the weight ratio of TS to SC was 1:3. Then, the cores were prepared with TS, SC and MCC at a weight ratio of 1:3:16 via extrusion-spheronization, followed by coating with Eudragit® RS30D/RL30D dispersion (9:1, w/w)...
February 6, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28163837/simultaneous-ramp-right-heart-catheterization-and-echocardiography-in-a-reliantheart-left-ventricular-assist-device
#19
Dipanjan Banerjee, Debleena Dutt, Sebastien Duclos, Karim Sallam, Matthew Wheeler, Richard Ha
Many clinicians caring for patients with continuous flow left ventricular assist devices (CF-LVAD) use ramp right heart catheterization (RHC) studies to optimize pump speed and also to troubleshoot CF-LVAD malfunction. An investigational device, the ReliantHeart Heart Assist 5 (Houston, TX), provides the added benefit of an ultrasonic flow probe on the outflow graft that directly measures flow through the CF-LVAD. We performed a simultaneous ramp RHC and echocardiogram on a patient who received the above CF-LVAD to optimize pump parameters and investigate elevated flow through the CF-LVAD as measured by the flow probe...
January 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28153941/decreases-in-maximal-oxygen-uptake-following-long-duration-spaceflight-role-of-convective-and-diffusive-o2-transport-mechanisms
#20
Carl J Ade, Ryan M Broxterman, Alan Moore, Thomas J Barstow
We have previously predicted that the decrease in maximal oxygen uptake (VO2max) that accompanies time in microgravity reflects decrements in both convective and diffusive O2 transport to the mitochondria of the contracting myocytes. The aim of this investigation was therefore to quantify the relative changes in convective O2 transport (QO2) and O2 diffusing capacity (DO2) following long duration spaceflight. In 9 astronauts, resting hemoglobin concentration ([Hb]), VO2max, maximal cardiac output (QTmax), and differences in arterial and venous O2 contents (CaO2-CvO2) were obtained retrospectively for International Space Station Increments 19 through 33 (April 2009-November 2012)...
February 2, 2017: Journal of Applied Physiology
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