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https://www.readbyqxmd.com/read/28087683/percutaneous-patent-ductus-arteriosus-pda-closure-during-infancy-a-meta-analysis
#1
REVIEW
Carl H Backes, Brian K Rivera, Jeffrey A Bridge, Aimee K Armstrong, Brian A Boe, Darren P Berman, Tyler Fick, Ralf J Holzer, Ziyad M Hijazi, Sylvia Abadir, Henri Justino, Lisa Bergersen, Charles V Smith, Haresh Kirpalani
CONTEXT: Patent ductus arteriosus (PDA) is a precursor to morbidity and mortality. Percutaneous (catheter-based) closure is the procedure of choice for adults and older children with a PDA, but use during infancy (<1 year) is not well characterized. OBJECTIVE: Investigate the technical success and safety of percutaneous PDA closure during infancy. DATA SOURCES: Scopus, Web of Science, Embase, PubMed, and Ovid (Medline) were searched through December 2015 with no language restrictions...
January 13, 2017: Pediatrics
https://www.readbyqxmd.com/read/28069213/effect-of-ultrasound-assisted-osmotic-dehydration-pretreatment-on-the-convective-drying-of-strawberry
#2
Ezzeddine Amami, Wissal Khezami, Salma Mezrigui, Laxmikant S Badwaik, Asma Kammoun Bejar, Carmen Tellez Perez, Nabil Kechaou
The work was planned to produce dietetic dehydrated strawberries with application of ultrasound osmotic dehydration (UOD) as pretreatment. A Box-Behnken design (BBD) were employed to characterize the UOD strawberry process, optimize and investigate the effect of independent variables like ultrasound time (10, 20 and 30min), concentration of osmotic solution (distilled water, 32.5 and 65 °Brix) and temperature (20, 30 and 40°C) on the water loss (WL), solid gain (SG) and weight reduction (WR). The same BBD were used to estimate the main effects of OD without ultrasound treatment...
May 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28063455/directed-drift-and-fluid-pumping-of-nanoswimmers-by-periodic-rectification-diffusion
#3
Yen-Fu Chen, Hsuan-Yi Chen, Yu-Jane Sheng, Heng-Kwong Tsao
The steady ratchet transport of run-and-tumble nanoswimmers in a 3D microfluidic channel constructed by periodic chambers separated by half-cylinder funnels is explored by dissipative particle dynamics. Two regions in a chamber are identified: rectification and active diffusion. While the concentration gradient is driven by the concentration jump in the rectification region, the ratchet current is dominated by the diffusion rate in the active diffusion region, which is classified into normal and Knudsen types...
January 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28061939/development-of-a-simplified-model-for-completely-mixed-biofilm-reactor
#4
Sushovan Sarkar, Debabrata Mazumder
  A simplified model for the completely mixed biofilm process formulated correlations between entering and exiting substrate concentrations, average substrate flux in the biofilm and effective biofilm thickness. The model essentially considered the substrate mass transport into the biofilm as per Fick's second law and steady state substrate as well as biomass balance for biofilm. The numerical solution of the biofilm model involved evaluation of the average flux along with exiting substrate concentration and application of the Runge-Kutta method for determining the effective biofilm thickness...
December 1, 2016: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28058437/sorting-ring-polymers-by-knot-type-with-modulated-nanochannels
#5
Mattia Marenda, Enzo Orlandini, Cristian Micheletti
In this theoretical study we discuss a novel method for sorting ring polymers according to their topological, knotted state. The proposed approach harnesses the rich dynamical behaviour of polymers confined inside spatially-modulated nanochannels. The longitudinal mobility of the rings is shown to have two key properties that are ideally suited for knot sorting. First, at fixed topology, the mobility has an intriguing oscillatory dependence on chain length. Second, the mobility ranking of different knot types is inverted upon increasing the chain length...
January 6, 2017: Soft Matter
https://www.readbyqxmd.com/read/28048346/su-f-t-660-evaluating-the-benefit-of-using-dual-function-fiducial-markers-for-in-situ-delivery-of-radiosenistizing-gold-nanoparticles-during-image-guided-radiotherapy
#6
S AlMansour, J Chin, E Sajo, W Ngwa
PURPOSE: Dual-function fiducials loaded with radiosensitizers, like gold nanoparticles (GNP), offer an innovative approach for ensuring geometric accuracy during image-guided radiotherapy (IGRT) and significantly increasing therapeutic efficacy due to controlled in-situ release of the radiosensitizers. This study retrospectively investigates the dosimetric benefit of using up to two such dual-function fiducial markers instead of traditional single function fiducials during IGRT. METHODS: A computational code was developed to investigate the dosimetric benefit for 10 real patient tumor volumes of up to 6...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28040174/evaluating-the-efficacy-of-beef-slaughter-line-interventions-by-quantifying-the-six-major-non-o157-shiga-toxin-producing-escherichia-coli-serogroups-using-real-time-multiplex-pcr
#7
Kaushi S T Kanankege, Kelly S Anklam, Catherine M Fick, Megan J Kulow, Charles W Kaspar, Barbara H Ingham, Andrew Milkowski, Dörte Döpfer
Six major Shiga toxin producing Escherichia coli (STEC) serogroups: O26, O103, O145, O111, O121, and O45 have been declared as adulterants in federally inspected raw beef in the USA effective June 4th, 2012 in addition to the routinely tested STEC O157: H7. This study tests a real-time multiplex PCR assay and pooling of the samples to optimize the detection and quantification (prevalence and contamination) of six major non-O157 STEC, regardless of possessing Shiga toxins. To demonstrate the practicality, one large-scale slaughter plant (Plant LS) and one small-scale slaughter plant (Plant SS) located in the Mid-Western USA were sampled, in 2011, before the establishment of 2013 USDA laboratory protocols...
May 2017: Food Microbiology
https://www.readbyqxmd.com/read/28017865/a-multi-scale-method-for-modelling-degradation-of-bioresorbable-polyesters
#8
Taohong Zhang, Shaonan Zhou, Xiaohao Gao, Zhiyong Yang, Leran Sun, Dezheng Zhang
: A multi-scale model using the Cellular Automata (CA) and kinetic Monte Carlo (KMC) methods is presented to simulate the degradation process of bioresorbable polyesters such as polylactide (PLA), polyglycolide (PGA) and their copolymers. The model considers the underlying chemical and physical events such as polymer chain scission, oligomer production, crystallisation induced by polymer chain scissions, oligomer diffusion and microstructure evolution due to erosion of the small chains...
December 22, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27984011/balancing-service-and-education-an-aaim-consensus-statement
#9
Jillian S Catalanotti, Alpesh N Amin, Kelly Caverzagie, Janice Gilden, Katherine Walsh, Steve F Vinciguerra, Heather S Laird-Fick
No abstract text is available yet for this article.
October 27, 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27973514/out-of-equilibrium-force-measurements-of-dual-fiber-optical-tweezers
#10
Jochen Fick
Optical trapping of micron-size dielectric particles in a dual-fiber tip configuration is presented. Trap oscillation and suspension flow experiments are performed to investigate the linearity of the optical forces. These measurements are completed by standard methods such as Boltzmann statistics or power spectra evaluation. Strong trapping efficiencies of 0.25 and 1.8  pN·μm<sup>-1</sup> have been found in the axial and transverse directions, respectively. The values obtained by the different approaches are in good agreement...
December 15, 2016: Optics Letters
https://www.readbyqxmd.com/read/27965227/effects-of-ambulation-and-nondependent-transfers-on-vital-signs-in-patients-receiving-norepinephrine
#11
Rosario Arcaya Nievera, Ann Fick, Hilary K Harris
PURPOSE: To assess the safety of mobilizing patients receiving low-dose norepinephrine (0.05 μg/kg per min) by examining mean arterial pressure and heart rate before and after activity with parameters set by the physician. BACKGROUND: Norepinephrine is a peripheral vasoconstrictor administered for acute hypotension. During activity, blood flows to the periphery to supply muscles with oxygen, which may oppose the norepinephrine vasoconstriction. The safety of mobilizing patients receiving norepinephrine is unclear...
December 2016: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/27957851/conduction-channel-formation-and-dissolution-due-to-oxygen-thermophoresis-diffusion-in-hafnium-oxide-memristors
#12
Suhas Kumar, Ziwen Wang, Xiaopeng Huang, Niru Kumari, Noraica Davila, John Paul Strachan, David Vine, A L David Kilcoyne, Yoshio Nishi, R Stanley Williams
Transition-metal-oxide memristors, or resistive random-access memory (RRAM) switches, are under intense development for storage-class memory because of their favorable operating power, endurance, speed, and density. Their commercial deployment critically depends on predictive compact models based on understanding nanoscale physicochemical forces, which remains elusive and controversial owing to the difficulties in directly observing atomic motions during resistive switching, Here, using scanning transmission synchrotron X-ray spectromicroscopy to study in situ switching of hafnium oxide memristors, we directly observed the formation of a localized oxygen-deficiency-derived conductive channel surrounded by a low-conductivity ring of excess oxygen...
December 27, 2016: ACS Nano
https://www.readbyqxmd.com/read/27933944/diffusion-in-multicomponent-liquids-from-microscopic-to-macroscopic-scales
#13
G Guevara-Carrion, Y Gaponenko, T Janzen, J Vrabec, V Shevtsova
In spite of considerable research on the nature of aqueous alcohol mixtures that are characterized by microscopic inhomogeneity or incomplete mixing at the molecular level, transport properties have received little attention. We report the results of a study on diffusion in the ternary mixture of water with two alcohols, that is, water + methanol + ethanol, which is investigated on microscopic and macroscopic scales by means of molecular simulation and Taylor dispersion experiments. A novel protocol is developed for the comparison of mutual diffusion coefficients sampled by two fundamentally different approaches, which allows for their critical analysis...
December 1, 2016: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/27922016/gabaergic-anxiolytic-drug-in-water-increases-migration-behaviour-in-salmon
#14
Gustav Hellström, Jonatan Klaminder, Fia Finn, Lo Persson, Anders Alanärä, Micael Jonsson, Jerker Fick, Tomas Brodin
Migration is an important life-history event in a wide range of taxa, yet many migrations are influenced by anthropogenic change. Although migration dynamics are extensively studied, the potential effects of environmental contaminants on migratory physiology are poorly understood. In this study we show that an anxiolytic drug in water can promote downward migratory behaviour of Atlantic salmon (Salmo salar) in both laboratory setting and in a natural river tributary. Exposing salmon smolt to a dilute concentration of a GABAA receptor agonist (oxazepam) increased migration intensity compared with untreated smolt...
December 6, 2016: Nature Communications
https://www.readbyqxmd.com/read/27911393/a-detailed-protocol-for-perspiration-monitoring-using-a-novel-small-wireless-device
#15
Kazuhiro Ogai, Masakazu Fukuoka, Kei-Ichiro Kitamura, Kiyoshi Uchide, Tetsu Nemoto
Perspiration monitoring can be utilized for the detection of certain diseases, such as thermoregulation and mental disorders, particularly when the patients are unaware of such disorders or are having difficulty expressing their symptoms. Until now, several devices for perspiration monitoring have been developed; however, such devices tend to have a relatively large exterior, considerable power consumption, and/or less sensitivity. Recently, we developed a small, wireless device for perspiration monitoring...
November 24, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27904162/impact-of-catheterization-lab-computer-software-settings-on-hemodynamic-assessment-of-aortic-stenosis
#16
Zaher Fanari, Anitha Rajamanickam, Mathew Grove, Sumaya Hammami, Cassie Walls, Paul Kolm, William Weintraub, Andrew J Doorey
BACKGROUND: Accurate assessment of Cardiac Output (CO) is a critical measurement in the calculation of aortic valve area (AVA). Due to the known inaccuracy of estimated Fick calculations, many measure thermodilution (TD) CO as well due to previous studies showing better correlation with the gold standard direct CO. Previous studies showed suboptimal correlation between both methods. Most physicians assume that the TD CO is chosen by catheterization laboratory software for AVA evaluation...
July 2016: Delaware Medical Journal
https://www.readbyqxmd.com/read/27890572/preservative-loss-from-silicone-tubing-during-filling-processes
#17
Verena Saller, Julia Matilainen, Christian Rothkopf, Daniel Serafin, Karoline Bechtold-Peters, Hanns-Christian Mahler, Wolfgang Friess
Significant loss of preservative was observed during filling of drug products during filling line stops. This study evaluated the losses of three commonly used preservatives in protein drugs, i.e. benzyl alcohol, phenol, and m-cresol. Concentration losses during static incubation were quantified and interpreted with regard to the potential driving forces for the underlying sorption, diffusion, and desorption steps. Partitioning from the solution into the silicone polymer was identified as the most decisive parameter for the extent of preservative loss...
November 23, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27881556/nitrite-and-s-nitrosohemoglobin-exchange-across-the-human-cerebral-and-femoral-circulation-relationship-to-basal-and-exercise-blood-flow-responses-to-hypoxia
#18
Damian M Bailey, Peter Rasmussen, Morten Overgaard, Kevin A Evans, Aske M Bohm, Thomas Seifert, Patrice Brassard, Morten Zaar, Henning B Nielsen, Peter Raven, Niels H Secher
BACKGROUND: -The mechanisms underlying red blood cell (RBC)-mediated hypoxic vasodilation remain controversial with separate roles for nitrite (NO2(-)) and S-nitrosohemoglobin (SNO-Hb) widely contested given their ability to transduce nitric oxide (NO) bioactivity within the microcirculation. To establish their relative contribution in vivo, we quantified arterial-venous (a-v) concentration gradients across the human cerebral and femoral circulation at rest and during exercise, an ideal model system characterized by physiological extremes of O2 tension and blood flow...
November 15, 2016: Circulation
https://www.readbyqxmd.com/read/27866929/long-term-outcomes-of-pulmonary-arterial-hypertension-under-specific-drug-therapy-in-eisenmenger-syndrome
#19
Sébastien Hascoët, Alban-Elouen Baruteau, Marc Humbert, Gérald Simonneau, Xavier Jais, Jérôme Petit, Daniela Laux, Olivier Sitbon, Virginie Lambert, André Capderou
BACKGROUND: The long-term effectiveness of pulmonary arterial hypertension-specific drug therapy (PAH-SDT) in Eisenmenger syndrome is controversial. We investigated short-term and long-term hemodynamic changes under PAH-SDT and their associations with outcomes in a bicentric cohort. METHODS: Over 20 years, we included 69 patients with congenital heart disease, an indexed pulmonary vascular resistance (PVRi) >8 WU·m(2), and 292 standardized catheterizations at baseline and after PAH-SDT initiation or intensification...
October 15, 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27866736/assessing-the-transport-of-pah-in-the-surficial-sediment-layer-by-passive-sampler-approach
#20
Angel Belles, Claire Alary, Justine Criquet, Anastasia Ivanovsky, Gabriel Billon
A new method based on passive samplers has been developed to assess the diffusive flux of fluorene, fluoranthene and pyrene in the sediment bed and across the sediment-water interface. The dissolved compound concentration gradient in the sediment in the vertical direction was measured at the outlet of a storm water pond by using polyethylene strips as passive samplers. Simultaneously, the dissipation of a set of tracer compounds preloaded in the passive samplers was measured to estimate the effective diffusion coefficients of the pollutants in the sediment...
February 1, 2017: Science of the Total Environment
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