Matthias Mattke, Matteo Ohlinger, Nina Bougatf, Robert Wolf, Thomas Welzel, Falk Roeder, Sabine Gerum, Christoph Fussl, Natalee Annon-Eberharter, Malte Ellerbrock, Oliver Jäkel, Thomas Haberer, Klaus Herfarth, Matthias Uhl, Jürgen Debus, Katharina Seidensaal, Semi Harrabi
BACKGROUND: The current study aims to evaluate the occurrence of temporal lobe reactions and identify possible risk factors for patients who underwent particle therapy of the skull base. METHODS: 244 patients treated for skull base chordoma ( n = 144) or chondrosarcoma ( n = 100) at the Heidelberg Ion Beam Therapy Center (HIT) using a raster scan technique, were analyzed. Follow-up MRI-scans were matched with the initial planning images. Radiogenic reactions were contoured and analyzed based on volume and dose of treatment...
February 8, 2024: Cancers