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https://www.readbyqxmd.com/read/29039565/hydrogen-sulfide-regulates-bone-remodeling-and-promotes-orthodontic-tooth-movement
#1
Haiya Pu, Yongmei Hua
Hydrogen sulfide (H2S) is a gas signaling molecule that has multiple influences on physiological and pathological processes in the mammalian body, including vasodilation, neurotransmission, inflammation, hypoxia sensing and bone remodeling. Our previous studies suggested that H2S might be involved in the periodontal tissue remodeling during the orthodontic tooth movement (OTM) via increasing periodontal ligament cell differentiation, tissue mineralization, bone formation and collagen synthesis. The aim of the present study was to investigate the effects of H2S on alveolar bone remodeling that is associated with tooth movement...
October 17, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29036235/-medicaments-and-oral-healthcare-5-adverse-effects-of-medications-and-over-the-counter-drugs-on-teeth
#2
C de Baat, P G M A Zweers, C van Loveren, A Vissink
Intrinsic tooth discoloration may occur as an adverse effect of fluoride and tetracyclines. Extrinsic tooth discoloration may occur as superficial staining or as discoloration of the superficial pellicle and/or biofilm due to chlorhexidine, liquid iron salts, essential oils, some antibiotics and stannous fluoride. Inhibition of orthodontic tooth movement has been reported due to the use of prostaglandin synthetase inhibitors. If medications or over-the-counter drugs induce hyposalivation or contain much sucrose, caries may develop...
October 2017: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/29016741/the-effect-of-low-level-laser-therapy-on-orthodontically-induced-root-resorption-a-pilot-double-blind-randomized-controlled-trial
#3
Doreen Ng, Ambrose K Chan, Alexandra K Papadopoulou, Oyku Dalci, Peter Petocz, Mehmet Ali Darendeliler
Background: The effect of low-level laser therapy (LLLT) on accelerating orthodontic tooth movement has been extensively studied; however, there is limited knowledge on the use of LLLT on orthodontic root resorption. Objective: To investigate the effect of LLLT on orthodontically induced inflammatory root resorption (OIIRR) and to compare the difference between pulsed and continuous LLLT on OIIRR. Trial design: Double-blind, single-centre 3-arm parallel split-mouth randomized controlled trial...
September 7, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/29016190/effect-of-flapless-osteoperforation-assisted-tooth-movement-on-atrophic-alveolar-ridge-histomorphometric-and-gene-enrichment-analysis
#4
Ji-Won Lee, Jung-Yul Cha, Ki-Ho Park, Yoon-Goo Kang, Su-Jung Kim
OBJECTIVE: To investigate the effect of flapless osteoperforation on the tissue response of the atrophic alveolar ridge affected by orthodontic tooth movement (OTM). MATERIALS AND METHODS: An atrophic alveolar ridge model was established in the mandibular quadrants of eight beagle dogs. As a split-mouth design, the quadrants were randomly divided into group C (OTM only) and group OP (OTM with flapless osteoperforation). The rate of OTM for 10 weeks was compared between groups, and micro-CT-based histomorphometric analysis and RNA-sequencing-based gene-enrichment analysis were performed targeting the atrophic ridge...
October 10, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28993918/a-new-albumin-depletion-strategy-improves-proteomic-research-of-gingival-crevicular-fluid-from-periodontitis-patients
#5
Sarah Batschkus, Goekhan Cingoez, Henning Urlaub, Nicolai Miosge, Christian Kirschneck, Philipp Meyer-Marcotty, Christof Lenz
OBJECTIVES: Gingival crevicular fluid (GCF), the inflammatory infiltrate within the crevicular sulcus, is of great importance for diverse processes in the oral cavity and has a high impact in oral sciences. It is assumed to serve as a source of biomarkers for systemic or periodontal diseases and mediators of orthodontic tooth movement. In order to characterize the protein content of the GCF in an unbiased and complete approach, we employed mass spectrometry (MS), which allows not only the identification, but also the quantification of these proteins...
October 9, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28989148/-effect-of-growth-hormone-on-osteopontin-expression-during-orthodontic-tooth-movement-in-rats
#6
Hualong Ju, Xiuying Cai
To investigate the effect of growth hormone on osteopontin expression during orthodontic tooth movement in rats.
 Methods: Forty male Wistar rats (2 weeks, average weight 200 g) were randomly divided into a control group and an experimental group (n=20 per group). The experimental group received subcutaneous injections of growth hormone at a dose of 0.15 U/(kg.d), and the control group received equivalent volumes of saline. A nickel-titanium spring was fixed between the maxillary incisors and the left upper first molar with a force of 0...
September 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28967333/american-academy-of-periodontology-best-evidence-consensus-statement-on-selected-oral-applications-for-cone-beam-computed-tomography
#7
George A Mandelaris, E Todd Scheyer, Marianna Evans, David Kim, Bradley McAllister, Marc L Nevins, Hector F Rios, David Sarment
BACKGROUND: The American Academy of Periodontology (AAP) recently embarked on a Best Evidence Consensus (BEC) model of scientific inquiry to address questions of clinical importance in periodontology for which there is insufficient evidence to arrive at a definitive conclusion. This review addresses oral indications for use of cone-beam computed tomography (CBCT). METHODS: To develop the BEC, the AAP convened a panel of experts with knowledge of CBCT and substantial experience in applying CBCT to a broad range of clinical scenarios that involve critical structures in the oral cavity...
October 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28967331/cone-beam-computed-tomography-and-interdisciplinary-dentofacial-therapy-an-american-academy-of-periodontology-best-evidence-review-focusing-on-risk-assessment-of-the-dentoalveolar-bone-changes-influenced-by-tooth-movement
#8
George A Mandelaris, Rodrigo Neiva, Leandro Chambrone
BACKGROUND: The aim of this systematic review is to evaluate whether cone-beam computed tomography (CBCT) imaging can be used to assess dentoalveolar anatomy critical to the periodontist when determining risk assessment for patients undergoing orthodontic therapy using fixed or removable appliances. METHODS: Both observational and interventional trials reporting on the use of CBCT imaging assessing the impact of orthodontic/dentofacial orthopedic treatment on periodontal tissues (i...
October 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28960194/regular-nicotine-intake-increased-tooth-movement-velocity-osteoclastogenesis-and-orthodontically-induced-dental-root-resorptions-in-a-rat-model
#9
Christian Kirschneck, Michael Maurer, Michael Wolf, Claudia Reicheneder, Peter Proff
Orthodontic forces have been reported to significantly increase nicotine-induced periodontal bone loss. At present, however, it is unknown, which further (side) effects can be expected during orthodontic treatment at a nicotine exposure corresponding to that of an average European smoker. 63 male Fischer344 rats were randomized in three consecutive experiments of 21 animals each (A/B/C) to 3 experimental groups (7 rats, 1/2/3): (A) cone-beam-computed tomography (CBCT); (B) histology/serology; (C) reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR)/cotinine serology-(1) control; (2) orthodontic tooth movement (OTM) of the first and second upper left molar (NiTi closed coil spring, 0...
September 2017: International Journal of Oral Science
https://www.readbyqxmd.com/read/28953142/wide-linear-corticotomy-and-anterior-segmental-osteotomy-under-local-anesthesia-combined-corticision-for-correcting-severe-anterior-protrusion-with-insufficient-alveolar-housing
#10
Min-Ki Noh, Baek-Soo Lee, Shin-Yeop Kim, Hyeran Helen Jeon, Seong-Hun Kim, Gerald Nelson
BACKGROUNDS: This article presents an alternate surgical treatment method to correct a severe anterior protrusion in an adult patient with an extremely thin alveolus. To accomplish an effective and efficient anterior segmental retraction without periodontal complications, the authors performed, under local anesthesia, a wide linear corticotomy and corticision in the maxilla and an anterior segmental osteotomy in mandible. METHODS: In the maxilla, a wide linear corticotomy was performed under local anesthesia...
September 25, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28949371/comparison-of-hif1a%C3%A2-as1-and-hif1a%C3%A2-as2-in-regulating-hif%C3%A2-1%C3%AE-and-the-osteogenic-differentiation-of-pdlcs-under-hypoxia
#11
Dongru Chen, Liping Wu, Lu Liu, Qimei Gong, Jinxuan Zheng, Caixia Peng, Jianqing Deng
Hypoxia‑inducible factor‑1α (HIF‑1α) is essential for regulating the osteogenic differentiation of periodontal ligament cells (PDLCs). The regulatory mechanism of HIF‑1α transcription is still not clear. Recently, two long non‑coding RNAs, HIF1A antisense RNA 1 (HIF1A‑AS1) and HIF1A antisense RNA 2 (HIF1A‑AS2), were found to regulate HIF‑1α mRNA, but the regulatory mechanisms among HIF‑1α, HIF1A‑AS1 and HIF1A‑AS2 have not been well studied. We hypothesized that HIF1A‑AS1 and HIF1A‑AS2 play important roles in the osteogenic differentiation of PDLCs by regulating HIF‑1α...
September 15, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28937886/effectiveness-of-biology-based-methods-for-inhibiting-orthodontic-tooth-movement-a-systematic-review
#12
M Cadenas de Llano-Pérula, R M Yañez-Vico, E Solano-Reina, J C Palma-Fernandez, A Iglesias-Linares
INTRODUCTION: Several experimental studies in the literature have tested different biology-based methods for inhibiting or decreasing orthodontic tooth movement (OTM) in humans. This systematic review investigated the effects of these interventions on the rate of tooth movement. STUDY DESIGN: Electronic [MedLine; SCOPUS; Cochrane Library; OpenGrey;Web of Science] and manual searches were conducted up to January 26th, 2016 in order to identify publications of clinical trials that compared the decreasing or inhibiting effects of different biology-based methods over OTM in humans...
September 22, 2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28923271/biological-effects-of-orthodontic-tooth-movement-into-the-grafted-alveolar-cleft
#13
Jian Sun, Xiaoyue Zhang, Renmei Li, Zhengxi Chen, Yuanliang Huang, Zhenqi Chen
PURPOSE: Functional stimulus during orthodontic tooth movement into the grafted bone can lead to better alveolar bone grafting outcomes. The aim of this study was to analyze the biological effects of orthodontic tooth movement into the grafted alveolar cleft area with histologic staining, fluorescence staining, and real-time polymerase chain reaction (PCR). MATERIALS AND METHODS: An animal model of orthodontic tooth movement into the grafted alveolar cleft area was established in 8-week-old Sprague-Dawley rats...
August 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28906140/evaluation-of-maxillary-central-incisors-on-the-noncleft-and-cleft-sides-in-patients-with-unilateral-cleft-lip-and-palate-part-2-relationship-between-root-resorption-horizontal-tooth-movement-and-quantity-of-grafted-autogenous-bone
#14
Aya Maeda-Iino, Minami Furukawa, Sangho Kwon, Kanako Marutani, Shoko Nakagawa, Takao Fuchigami, Norifumi Nakamura, Shouichi Miyawaki
OBJECTIVE: To evaluate the relationship between external apical root resorption (EARR) of the maxillary central incisors (U1), horizontal orthodontic tooth movement, and quantity of grafted bone in subjects with unilateral cleft lip and palate (UCLP) over an average duration of 8 years. MATERIALS AND METHODS: Thirty subjects with UCLP were evaluated for EARR of U1 after edgewise treatment (T2). The teeth were classified as having no EARR, moderate EARR (combined into "no/moderate" EARR), or severe EARR...
September 14, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28906139/evaluation-of-maxillary-central-incisors-on-the-noncleft-and-cleft-sides-in-patients-with-unilateral-cleft-lip-and-palate-part-1-relationship-between-root-length-and-orthodontic-tooth-movement
#15
Aya Maeda-Iino, Kanako Marutani, Minami Furukawa, Shoko Nakagawa, Sangho Kwon, Toshiro Kibe, Masahiro Tezuka, Norifumi Nakamura, Shouichi Miyawaki
OBJECTIVES: To measure the root lengths of maxillary central incisors (U1) and evaluate the relationship among U1 root length, tooth movement, and type of treatment appliance in patients with unilateral cleft lip and palate over a long-term follow-up period. MATERIALS AND METHODS: Occlusal radiographs of 30 patients with unilateral cleft lip and palate, acquired less than 6 months before secondary alveolar bone grafting (SBG, T1) and after edgewise treatment (T2), were measured for U1 root length (R1 and R2, root lengths at T1 and T2, respectively)...
September 14, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28902245/tooth-resorptions-are-not-hereditary
#16
Alberto Consolaro, Débora de Almeida Bianco
Root resorptions caused by orthodontic movement are not supported by consistent scientific evidence that correlate them with heredity, individual predisposition and genetic or familial susceptibility. Current studies are undermined by methodological and interpretative errors, especially regarding the diagnosis and measurements of root resorption from orthopantomographs and cephalograms. Samples are heterogeneous insofar as they comprise different clinical operators, varied types of planning, and in insufficient number, in view of the prevalence of tooth resorptions in the population...
July 2017: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/28893054/effect-of-methylphenidate-on-orthodontic-tooth-movement-and-histological-features-of-bone-tissue-in-rats-an-experimental-study
#17
Hossein Aghili, Soghra Yassaei, Shokouh Taghipour Zahir, Rahele Arjmandi
INTRODUCTION: Methylphenidate is a psychostimulant drug, which is commonly used by children and teenagers. This age group receives most orthodontic treatment. Effect of this drug on tooth movement is unknown. AIM: The aim of this study was to evaluate the effect of methylphenidate on orthodontic tooth movement and histological features of bone tissue in rats. MATERIALS AND METHODS: Forty-two Wistar rats (male) were selected and divided to three groups, randomly (n=14)...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28876390/the-influence-of-non-steroidal-anti-inflammatory-drugs-and-paracetamol-used-for-pain-control-of-orthodontic-tooth-movement-a-systematic-review
#18
Adriano S Corrêa, Vinícius L DE Almeida, Beatriz M V Lopes, Ademir Franco, Felipe R DE Matos, Lucindo J Quintans-Júnior, Sigmar M Rode, Luiz R Paranhos
The present study aimed to perform a systematic literature review to determine if there is a non-steroidal anti-inflammatory drug (NSAID) that interferes less within tooth movement. This research was performed according to the PRISMA statement. Articles were searched in eight electronic databases (PubMed, Scopus, Embase, Web of Science, LILACS, SciELO, Google Scholar, and Open Grey). Only experimental studies on male Wistar rats were selected, which included experiments related to the influence of NSAIDs on orthodontic movement...
August 31, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28866437/adiponectin-prevents-orthodontic-tooth-movement-in-rats
#19
Sigrid Haugen, Kristin Matre Aasarød, Astrid Kamilla Stunes, Mats Peder Mosti, Tanya Franzen, Vaska Vandevska-Radunovic, Unni Syversen, Janne Elin Reseland
OBJECTIVE: The objective was to examine the effects of repetitive local administration of adiponectin on experimental tooth movement in rats. MATERIALS AND METHODS: The maxillary right first molar of male Wistar rats (n=24) was moved mesially for 14days, with local adiponectin injections (0.2 or 2μg) every third day. Micro-computed tomography was performed at days 0, 6 and 14 and molar movement, bone density and bone volume fraction were calculated from the scans...
August 26, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28865823/insufficient-evidence-supports-the-use-of-low-level-laser-therapy-to-accelerate-tooth-movement-prevent-orthodontic-relapse-and-modulate-acute-pain-during-orthodontic-treatment
#20
Adrian Farsaii, Thikriat Al-Jewair
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Efficacy of low-level laser therapy in accelerating tooth movement, preventing relapse and managing acute pain during orthodontic treatment in humans: A systematic review. Sonesson M, De Geer E, Subraian J, Petrén S. BMC Oral Health 2017;17:11. SOURCE OF FUNDING: No funding was obtained for this study TYPE OF STUDY/DESIGN: Systematic review.
September 2017: Journal of Evidence-based Dental Practice
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