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orthodontic tooth movement

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https://www.readbyqxmd.com/read/28102013/the-effect-of-potassium-diclofenac-and-dexamethasone-on-mmp-1-gene-transcript-levels-during-experimental-tooth-movement-in-rats
#1
G P Molina Da Silva, O M Tanaka, D F Campos Navarro, C E Repeke, G P Garlet, O Guariza-Filho, P C Trevilatto
OBJECTIVES: The aim of this study was to analyze MMP-1 transcript levels in periodontal tissues of rats that underwent orthodontic treatment using potassium diclofenac and dexamethasone at different stages of tooth movement. SETTING AND SAMPLE POPULATION: The sample comprised of ninety male Wistar rats. MATERIAL AND METHODS: A closed nickel-titanium coil spring was used to apply a force of 50 cN to move the maxillary right first molars mesially...
February 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28078880/orthodontic-forces-modulate-insulin-like-growth-factor-binding-protein-5-changes-in-gingival-crevicular-fluid
#2
A Ballini, L Santacroce, S Cantore, R Saini, F Mastrangelo, A Desiate, S Scacco
Orthodontic tooth movement results from the response of the periodontal tissue to orthodontic force, which leads to modeling and remodeling of the surrounding alveolar bone. The response is considered to occur through the activation of specific signaling pathways, many of which are known, all acting to ultimately result in tooth movement. Much is known about the actions of these two cells, and the signaling pathways that affect them, both in bone and orthodontic literature, however, to date, little work has been carried out to examine the effect of the insulin-like growth factor binding proteins (IGFBP) in orthodontics...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28076465/the-effect-of-capsaicin-on-expression-patterns-of-cgrp-in-trigeminal-ganglion-and-trigeminal-nucleus-caudalis-following-experimental-tooth-movement-in-rats
#3
Zhou Yang, Long Hu, Y E Niansong, Liao Lina, Yang Xin, Jian Fan, Wang Yan, Lai Wenli
Objectives: The aim of this study was to explore the effect of capsaicin on expression patterns of calcitonin gene-related peptide (CGRP) in the trigeminal ganglion (TG) and trigeminal subnucleus caudalis (Vc) following experimental tooth movement. Material and Methods: Male Sprague-Dawley rats were used in this study and divided into small-dose capsaicin+force group, large-dose capsaicin+force group, saline+force group, and no force group. Closed coil springs were used to mimic orthodontic forces in all groups except for the no force group, in which springs were inactivated...
November 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28060561/aspirin-blocks-orthodontic-relapse-via-inhibition-of-cd4-t-lymphocytes
#4
Y Liu, T Zhang, C Zhang, S S Jin, R L Yang, X D Wang, N Jiang, Y H Gan, X X Kou, Y H Zhou
Immunologic response plays an important role in orthodontic tooth movement (OTM) and relapse. Nonsteroidal anti-inflammatory drugs, such as aspirin, affect immune cells and clinical orthodontic treatment. However, the mechanisms by which nonsteroidal anti-inflammatory drugs regulate immune cells to affect orthodontic relapse are unclear. In this study, male Sprague-Dawley rats were grouped as relapse and relapse + aspirin for 10 d after 14 d of OTM. Silicone impressions of the rats' maxillary dentitions were obtained to record the distance of OTM at the indicated time point...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28050063/a-radiographic-study-of-external-apical-root-resorption-in-patients-treated-with-single-phase-fixed-orthodontic-therapy
#5
S S Agarwal, S S Chopra, Prasanna Kumar, B Jayan, K Nehra, Mohit Sharma
BACKGROUND: External apical root resorption (EARR) is one of the most common iatrogenic consequences of orthodontic tooth movement. Many factors like gender, duration, orthodontic force and duration of orthodontic treatment have been implicated to cause EARR. METHODS: Pre- and post-treatment OPGs of 60 orthodontic patients (30 males and 30 females) who had undergone treatment with a single phase of fixed orthodontic therapy were randomly selected from institutional archives...
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28045320/extrusion-of-severely-impacted-mandibular-first-molar-using-partial-orthodontics-and-temporary-anchorage-miniscrews
#6
R Rodriguez Y Baena, M S Lupi, G Ceriana, M F Sfondrini, A Scribante
BACKGROUND: This study reports a case in which a severely impacted lower first molar was recovered with a combined orthodontic therapy and minimally invasive oral surgery with special focus to patient's aesthetic demands. CASE REPORT: A 12-year- old female patient was complaining delayed eruption of mandibular right first molar. Radiographic exam showed a severe tooth impaction with a close relationship between tooth roots and mandibular nerve. As the patient refused full arches orthodontic treatment, a partial orthodontic approach was projected...
December 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28044198/meloxicam-medication-reduces-orthodontically-induced-dental-root-resorption-and-tooth-movement-velocity-a-combined-in-vivo-and-in-vitro-study-of-dental-periodontal-cells-and-tissue
#7
Christian Kirschneck, Matthias Meier, Kathrin Bauer, Peter Proff, Jochen Fanghänel
Non-steroidal anti-inflammatory drugs (NSAID) are used to alleviate pain sensations during orthodontic therapy but are also assumed to interfere with associated pseudo-inflammatory reactions. In particular, the effects of partially selective COX-2 inhibition over the constitutively expressed COX-1 (11:1) on periodontal cells and tissue, as induced by the NSAID meloxicam, remain unclear. We investigate possible adverse side-effects and potentially useful beneficial effects during orthodontic therapy and examine underlying cellular and tissue reactions...
January 3, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28024792/effects-of-local-platelet-rich-plasma-injection-on-the-rate-of-orthodontic-tooth-movement-in-a-rat-model-a-histomorphometric-study
#8
Ayşegül Güleç, Banu Çakırer Bakkalbaşı, Alev Cumbul, Ünal Uslu, Burçin Alev, Ayşen Yarat
INTRODUCTION: The aims of this study were to determine the effects of different concentrations of platelet-rich plasma (PRP) on alveolar bone density and orthodontic tooth movement. METHODS: Seventy-six rats were divided into 2 groups: a moderate concentration PRP injection group (n = 38) and a high concentration PRP injection group (n = 38). In each group, 5 time points were studied: 3, 7, 14, 21, and 60 days. Before orthodontic mesialization of the maxillary first molars, moderate and high concentrations of PRP were injected on the right sides of the molar buccal sulcus, and the left sides served as the controls...
January 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27997984/the-relationship-between-lip-closing-force-and-dental-arch-morphology-in-patient-with-angle-class-i-malocclusion
#9
Yoshie Takehana, Yuji Masuda, Toru Kageyama, Rurika Okazaki, Madoka Murakami, Kazuhiro Yamada
Dental arch morphology and tooth position are affected by lip-closing force (LCF). This study aimed to quantitatively evaluate the relationships between the horizontal or vertical balance of the LCF generated during maximum voluntary pursing-like movements and dental arch length (DAL) or width (DAW) or the lingual inclination of the upper or lower 1st molars (LIUM, LILM) in patients with Angle Class I malocclusion. Sixteen subjects with Angle Class I malocclusion (median age: 23.4±5.9 years) who had never undergone orthodontic treatment were randomly selected...
December 20, 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/27982227/effects-of-zoledronic-acid-on-orthodontic-tooth-movement-in-rats
#10
Marcel Durante Brunet, Cristiano Miranda de Araujo, Aline Cristina Batista Rodrigues Johann, Elisa Souza Camargo, Orlando Motohiro Tanaka, Odilon Guariza
The purpose of this study was to assess the effects of the administration of zoledronic acid (ZA) during orthodontic movement in rats. A hundred and twenty male Wistar rats were applied force of 30 cN with spring closed nickel-titanium to move the upper right first molar to mesial. In the Control Movement group (CM), only tooth movement was performed; the Control Acid Zoledronic group (CAZ) received a single dose (0.1 mg/kg) of ZA; the Experimental Acid Zoledronic group (EAZ) received a single dose (0.1 mg/kg) one week prior to the start of tooth movement; and the Control Without movement group (CWM) that received no drug and without application of tooth movement...
September 2016: Brazilian Dental Journal
https://www.readbyqxmd.com/read/27981392/histological-evidence-that-metformin-reverses-the-adverse-effects-of-diabetes-on-orthodontic-tooth-movement-in-rats
#11
Jing Sun, Juan Du, Wei Feng, Boyao Lu, Hongrui Liu, Jie Guo, Norio Amizuka, Minqi Li
This study evaluated the effects of metformin on orthodontic tooth movement in a rat model of type 2 diabetes mellitus. Rats were fed a high-fat diet for 4 weeks to induce fat accumulation and insulin resistance, and then injected with a low dose of streptozotocin (35 mg/kg) intraperitoneally to induce type 2 diabetes. An orthodontic appliance was placed in normoglycemic, type 2 diabetes, and type 2 diabetes with metformin-administrated rats. After 14 days, type 2 diabetes rats exhibited greater orthodontic tooth movement and had a higher number of tartrate-resistant acid phosphatase-positive osteoclasts, stronger cathepsin K expression, and weaker alkaline phosphatase immunostaining than normoglycemic rats...
December 15, 2016: Journal of Molecular Histology
https://www.readbyqxmd.com/read/27979689/effect-of-intraoral-mechanical-stress-application-on-the-expression-of-a-force-responsive-prognostic-marker-associated-with-system-disease-progression
#12
Yimei Zhang, Xiaoxing Kou, Nan Jiang, Yan Liu, Franklin R Tay, Yanheng Zhou
OBJECTIVES: Malocclusion may be corrected nonsurgically by mechanical tooth movement. The plasma protein profiles of human subjects receiving the first phase of orthodontic treatment were examined to test the hypothesis that application of mechanical stresses to teeth induces systemic proteomic alterations. METHODS: Tandem mass tag-based liquid chromatography-mass spectrometry (LC-MS/MS) was used to examine systemic proteomic alterations in subjects undergoing controlled stress application (N=10) and in volunteers not receiving treatment (N=7) at 3 time intervals within 24h...
December 12, 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27957280/the-influence-of-teriparatide-in-induced-tooth-movement-a-systematic-review
#13
REVIEW
Bianca-Núbia Souza-Silva, José-Lucas-Sani-de Alcântara Rodrigues, Jefferson-Chaves Moreira, Felipe-de Souza Matos, Carla-Patrícia-Hernandez-Alves-Ribeiro Cesar, Carlos-Eduardo-Palanch Repeke, Luiz-Renato Paranhos
BACKGROUND: Teriparatide is a synthetic drug similar than PTH (parathyroid hormone), which is currently used as long-term treatment option for patients with bone chronic diseases, as osteoporosis; and this drug can interfere in a positive way in orthodontic movement. Objectives: The medical literature was assessed in the present systematic review in order to determine the level of scientific evidence supporting the influence of teriparatide in induced tooth movement. MATERIAL AND METHODS: The PRISMA Checklist was followed in this systematic review...
December 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27940164/rankl-release-from-self-assembling-nanofiber-hydrogels-for-inducing-osteoclastogenesis-in-vitro
#14
James Z Xing, Lei Lu, Larry D Unsworth, Paul W Major, Michael R Doschak, Neelambar R Kaipatur
PURPOSE: To develop a nanofiber hydrogel (NF-hydrogel) for sustained and controlled release of the recombinant receptor activator of NF-kB ligand; (RANKL) and to characterize the release kinetics and bioactivity of the released RANKL. METHODS: Various concentrations of fluorescently-labelled RANKL protein were added to NF-hydrogels, composed of Acetyl-(Arg-Ala-Asp-Ala)4-CONH2 [(RADA)4] of different concentrations, to investigate the resulting in vitro release rates...
December 7, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27905816/cementocyte-cell-death-occurs-in-rat-cellular-cementum-during-orthodontic-tooth-movement
#15
Humihiro Matsuzawa, Naoko Toriya, Yuya Nakao, Moe Konno-Nagasaka, Toshiya Arakawa, Miki Okayama, Itaru Mizoguchi
OBJECTIVE: To clarify the mechanism of root resorption during orthodontic treatment, we examined cementocyte cell death and root resorption in the cellular cementum on the pressure side during experimental tooth movement. MATERIALS AND METHODS: Using 8-week-old male Wistar rats, the right first molar was pushed mesiobuccally with a force of 40 g by a Ni-Ti alloy wire while the contralateral first molar was used as a control. Localization and number of cleaved caspase-3-positive and single-stranded DNA (ssDNA) - positive cells were evaluated using dual-label immunohistochemistry with anticleaved caspase-3 and anti-ssDNA antibodies...
December 1, 2016: Angle Orthodontist
https://www.readbyqxmd.com/read/27894545/ability-of-mini-implant-facilitated-micro-osteoperforations-to-accelerate-tooth-movement-in-rats
#16
Tracy Cheung, Juyoung Park, Deborah Lee, Catherine Kim, Jeffrey Olson, Shadi Javadi, Gregory Lawson, James McCabe, Won Moon, Kang Ting, Christine Hong
INTRODUCTION: Although current techniques for accelerated tooth movement often involve invasive surgical procedures, micro-osteoperforations (MOPs) using mini-implants may facilitate orthodontic tooth movement without raising flaps, reduce surgical risks, and increase patient acceptance. In this study, we evaluated the effectiveness of mini-implant-facilitated MOPs in inducing accelerated tooth movement and investigated the potential risks for root resorption. METHODS: Five MOPs were placed on the left side around the maxillary first molars in 6 rats using an automated mini-implant driver, whereas the right side received no MOPs as the control...
December 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27882108/effects-of-piezosurgery-in-accelerating-the-movement-of-orthodontic-alveolar-bone-tooth-of-rats-and-the-expression-mechanism-of-bmp-2
#17
Jinyou Han, Hong He
The aim of the study was to investigate the effects of piezosurgery in accelerating the movement of orthodontic alveolar bone tooth of rats and the expression mechanism of bone morphogenetic protein-2 (BMP-2). Adult male Wistar rats (n=30), with an age range of 14-15 weeks, and an average weight of 250±16 g were used. The animals were randomly divided into the control and observation groups. The rats in the control group were injected with 25-dihydroxyvitamin (1,25-dihydroxycholecalciferol) into their dental ligament...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27876452/comparison-of-excursive-occlusal-force-parameters-in-post-orthodontic-and-non-orthodontic-subjects-using-t-scan%C3%A2-iii
#18
Sarah Qadeer, Ahmed A Abbas, Lertrit Sarinnaphakorn, Robert B Kerstein
OBJECTIVE: Published studies indicate that orthodontically treated patients demonstrate increased posterior occlusal friction contributing to temporomandibular disorder (TMD) symptoms. This study investigated measured excursive movement occlusal contact parameters and their association with TMD symptoms between non- and post-orthodontic subjects. METHODS: Twenty-five post-orthodontic and 25 non-orthodontic subjects underwent T-Scan® computerized occlusal analysis to determine their disclusion time (DT), the excursive frictional contacts, and occlusal scheme...
November 23, 2016: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/27869476/low-level-laser-therapy-effectiveness-in-accelerating-orthodontic-tooth-movement-a-randomized-controlled-clinical-trial
#19
Mohammad Moaffak A AlSayed Hasan, Kinda Sultan, Omar Hamadah
OBJECTIVE: To evaluate the effectiveness of low-level laser therapy (LLLT) in accelerating orthodontic tooth movement of crowded maxillary incisors. MATERIALS AND METHODS: This two-arm, parallel-group, randomized controlled trial involved 26 patients with severe to extreme maxillary incisors irregularity according to Little's irregularity index, indicating two first premolars extraction. Patients were randomly assigned to either the laser group or the control group (13 each)...
November 21, 2016: Angle Orthodontist
https://www.readbyqxmd.com/read/27843261/autotransplantation-of-a-strange-positioned-impacted-central-incisor-in-a-surgically-prepared-socket-a-miracle-esthetic-concept
#20
Chandresh Jaiswara, Vinay K Srivastava, Neeraj Dhiman
: Esthetics is a prime concern for a young lady. Any anomaly in the anterior tooth may create anxiety and depression. This anxiety and depression may hamper her married life and overall personality. This case report reveals an unerupted right central incisor situated in a strange position, creating space in the maxillary anterior region and giving an unesthetic appearance. Autotransplantation is a method of choice for a strangely positioned impacted central incisor in a new appropriate site...
July 2016: International Journal of Clinical Pediatric Dentistry
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