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https://www.readbyqxmd.com/read/29355417/reminova-and-eaer-keeping-enamel-whole-through-caries-remineralization
#1
N B Pitts, J P Wright
This article aims to outline the early development of a King's College London dental spinout company, Reminova, formed to commercialize a novel clinical method of caries remineralization: electrically accelerated and enhanced remineralization (EAER). This method is being developed to address the unmet clinical need identified by modern caries management strategies to keep enamel "whole" through remineralization of clinical caries as a form of nonoperative caries treatment for initial-stage and moderate lesions...
February 2018: Advances in Dental Research
https://www.readbyqxmd.com/read/29337634/risk-factors-associated-with-open-gingival-embrasures-after-orthodontic-treatment
#2
Sang Su An, Yoon Jeong Choi, Ji Young Kim, Chooryung J Chung, Kyung-Ho Kim
OBJECTIVES: To investigate the incidence of and contributing factors to open gingival embrasures between the central incisors after orthodontic treatment. MATERIALS AND METHODS: One hundred posttreatment patients (29 men and 71 women; mean age, 24.7 years) were divided retrospectively into occurrence and nonoccurrence groups based on intraoral photographs. Based on the severity, the occurrence group was further divided into mild, moderate, and severe groups. Parameters from periapical radiographs, superimposed lateral cephalograms, and study models were compared between the occurrence and the nonoccurrence groups by using independent t-tests and were also analyzed on the basis of severity via analysis of variance...
January 16, 2018: Angle Orthodontist
https://www.readbyqxmd.com/read/29333593/control-of-anterior-segment-using-an-antero-posterior-lingual-sliding-retraction-system-a-preliminary-cone-beam-ct-study
#3
Min Hwang, Hyo-Won Ahn, Soon-Yong Kwon, Jeong-Ho Choi, Seong-Hun Kim, Gerald Nelson
BACKGROUND: This study was performed to evaluate the treatment effects of the antero-posterior lingual retractor (APLR), focusing on the 3-dimensional (3D) tooth movement of the maxillary anterior teeth and their alveolar bone levels. METHODS: En masse retraction was performed using either the C-lingual retractor (CLR, C-group, n = 9) or the antero-posterior lingual retractor (APLR, AP-group, n = 8). We evaluated 3D movement of the maxillary anterior teeth and alveolar bone levels, root length of the central incisors, long axes of the maxillary canines, and occlusal plane changes from CBCT images...
January 15, 2018: Progress in Orthodontics
https://www.readbyqxmd.com/read/29306536/orthodontic-movement-after-regenerative-endodontic-procedure-case-report-and-long-term-observations
#4
Antonis Chaniotis
INTRODUCTION: Although regenerative treatment approaches in teeth with incomplete root formation and pulp necrosis have become part of the suggested therapeutic endodontic spectrum, little is known about the effect of orthodontic movement in the tissue that has been regenerated. Furthermore, as the number of adults undergoing orthodontic treatment increases, there is an increasing need to investigate the changes that these tissues may undergo during orthodontic movement. Here we describe the alterations observed after the application of orthodontic forces in a case of an apically root-fractured necrotic immature root that had been managed with regenerative endodontic procedures in the past...
January 3, 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29303760/a-modified-frenectomy-technique-a-new-surgical-approach
#5
Mahdi Kadkhodazadeh, Reza Amid, Mehdi Ekhlasmand Kermani, Sepanta Hosseinpour
The frenum is a mucosal fold that attaches the lips or cheeks to the alveolar mucosa, gingiva, and underlying periosteum. Consequences of an abnormal frenal attachment include gingival recession, decreased vestibular depth, decreased range of lip movement, and involvement of interdental papilla, causing a diastema. Several methods to eliminate ectopic frenal attachments have been suggested, including frenectomy (elimination) and frenotomy (repositioning). This case report describes the use of a modified frenectomy technique in a 15-year-old girl with excess gingiva between the maxillary central incisors, which exhibited a 3-mm diastema...
January 2018: General Dentistry
https://www.readbyqxmd.com/read/29299161/n-ac-l-leu-pei-mediated-mir-34a-delivery-improves-osteogenic-differentiation-under-orthodontic-force
#6
Wenwen Yu, Yi Zheng, Zhujun Yang, Hongbo Fei, Yang Wang, Xu Hou, Xinhua Sun, Yuqin Shen
Rare therapeutic genes or agents are reported to control orthodontic bone remodeling. MicroRNAs have recently been associated with bone metabolism. Here, we report the in vitro and in vivo effects of miR-34a on osteogenic differentiation under orthodontic force using an N-acetyl-L-leucine-modified polyethylenimine (N-Ac-l-Leu-PEI) carrier. N-Ac-l-Leu-PEI exhibited low cytotoxicity and high miR-34a transfection efficiency in rat bone mineral stem cells and local alveolar bone tissue. After transfection, miR-34a enhanced the osteogenic differentiation of Runx2 and ColI, Runx2 and ColI protein levels, and early osteogenesis function under orthodontic strain in vitro...
December 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/29296110/effect-of-sodium-fluoride-mouthwash-on-the-frictional-resistance-of-orthodontic-wires
#7
Allahyar Geramy, Tabassom Hooshmand, Tahura Etezadi
Objectives: The friction between the brackets and orthodontic wire during sliding mechanics inflicts difficulties such as decreasing the applied force and tooth movement and also the loss of anchorage. Therefore, many studies have focused on the factors that affect the friction. The purpose of this study was to assess the effect of 0.05% sodium fluoride mouthwash on the friction between orthodontic brackets and wire. Materials and Methods: Four types of orthodontic wires including rectangular standard stainless steel (SS), titanium molybdenum alloy (TMA), nickel-titanium (NiTi) and copper-nickel-titanium (Cu-NiTi) were selected...
September 2017: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/29291189/osseous-outgrowth-on-the-buccal-maxilla-associated-with-piezosurgery-assisted-en-masse-retraction-a-case-series
#8
Nilüfer İrem Tunçer, Ayça Arman-Özçırpıcı, Bahar Füsun Oduncuoğlu, Alpdoğan Kantarcı
Piezoelectric surgery is a novel surgical approach used in orthodontic treatment for rapid tooth movement. This paper presents a case series wherein osseous outgrowths were observed in response to piezosurgery-assisted en-masse retraction. Sixteen patients requiring upper premolar extractions were treated with miniscrew-supported en-masse retraction and received minimally invasive decortication via piezosurgery. Computed tomography (CT) of the maxillary anterior region was performed to investigate the nature of the outgrowths...
January 2018: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/29291183/prediction-of-optimal-bending-angles-of-a-running-loop-to-achieve-bodily-protraction-of-a-molar-using-the-finite-element-method
#9
Woon-Kuk Ryu, Jae Hyun Park, Kiyoshi Tai, Yukio Kojima, Youngjoo Lee, Jong-Moon Chae
Objective: The purpose of this study was to predict the optimal bending angles of a running loop for bodily protraction of the mandibular first molars and to clarify the mechanics of molar tipping and rotation. Methods: A three-dimensional finite element model was developed for predicting tooth movement, and a mechanical model based on the beam theory was constructed for clarifying force systems. Results: When a running loop without bends was used, the molar tipped mesially by 9...
January 2018: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/29290679/heredity-genetics-and-orthodontics-how-much-has-this-research-really-helped
#10
James K Hartsfield, George Jeryn Jacob, Lorri Ann Morford
Uncovering the genetic factors that correlate with a clinical deviation of previously unknown etiology helps to diminish the unknown variation influencing the phenotype. Clinical studies, particularly those that consider the effects of an appliance or treatment regimen on growth, need to be a part of these types of genetic investigations in the future. While the day-to-day utilization of "testing" for genetic factors is not ready for practice yet, genetic testing for monogenic traits such as Primary Failure of Eruption (PFE) and Class III malocclusion is showing more promise as knowledge and technology advances...
December 2017: Seminars in Orthodontics
https://www.readbyqxmd.com/read/29287658/assessment-of-the-rate-of-premolar-extraction-space-closure-in-the-maxillary-arch-with-the-acceledent-aura-appliance-vs-no-appliance-in-adolescents-a%C3%A2-single-blind-randomized-clinical-trial
#11
RANDOMIZED CONTROLLED TRIAL
Peter Miles, Elizabeth Fisher, Nikolaos Pandis
INTRODUCTION: The purpose of this 2-arm parallel trial was to assess the effect of the AcceleDent Aura appliance (OrthoAccel Technologies, Houston, Tex) on the rate of maxillary premolar extraction space closure in adolescent patients. METHODS: Forty Class II adolescents treated with full fixed appliances and maxillary premolar extractions participated in this randomized clinical trial. They were recruited in a private practice and treated by 1 clinician. Randomization was accomplished in blocks of 10 patients assigned to either a no-appliance group or the AcceleDent Aura appliance group with the allocations concealed in opaque, sealed envelopes...
January 2018: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29282560/effects-of-corticopuncture-cp-and-low-level-laser-therapy-lllt-on-the-rate-of-tooth-movement-and-root-resorption-in-rats-using-micro-ct-evaluation
#12
Selly Sayuri Suzuki, Aguinaldo Silva Garcez, Patricia Oblitas Reese, Hideo Suzuki, Martha Simões Ribeiro, Won Moon
The aim of this study was to compare the rate of tooth displacement, quantity of root resorption, and alveolar bone changes in five groups: corticopuncture (CP), low-level laser therapy (LLLT), CP combined with LLLT (CP + LLLT), control (C), and negative control (NC). A total of 60 half-maxilla from 30 male Wistar rats (10 weeks old) were divided randomly into five groups: three (CP, LLLT, and CP + LLLT) test groups with different stimulation for accelerated-tooth-movement (ATM), one control (C) group, and one negative control (NC) group with no tooth movement...
December 27, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29274167/effects-of-photobiomodulation-on-sofat-a-t-cell-derived-cytokine-may-explain-accelerated-orthodontic-tooth-movement
#13
Viviane Jettar, Marcelo Napimoga, Fabiana Freitas, Juliana Clemente-Napimoga, Selly Suzuki, Victor Montalli, Aguinaldo Garcez
Orthodontic tooth movement is based on mechanical forces inducing bone remodeling and several methods have been proposed to increase tooth movement, including photobiomodulation. This study evaluated, in an animal model, the effects of photobiomodulation on SOFAT - a secreted osteoclastogenic factor of activated T cells and RANK-L during tooth movement. The results showed that tooth displacement, RANK-L and SOFAT levels were significantly greater compared to control group. SOFAT may play an important role in bone remodeling during orthodontic movement, possibly increasing the osteoclast cells at the compression area and bone remodeling activity...
December 23, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29249875/evaluation-of-fracture-resistance-of-ceramic-veneers-with-different-preparation-designs-and-loading-conditions-an-in-vitro-study
#14
Aman Arora, Viram Upadhyaya, Sheen J Arora, Prachi Jain, Avneet Yadav
Purpose: The purpose of this study was to evaluate the effect of incisal butt joint and incisal overlap design on the fracture resistance of ceramic veneers under two different loading conditions, i.e., 125° and 60° representing protrusive and intercuspal movements, respectively. Materials and Methods: Thirty-two maxillary central incisors were divided into two groups of sixteen specimens each and were prepared with incisal butt joint and incisal overlap design...
October 2017: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/29248944/surface-wear-of-resin-composites-used-for-invisalign%C3%A2-attachments
#15
Graciela J Barreda, Elizabeth A Dzierewianko, Karina A Muñoz, Gisela I Piccoli
Orthodontic treatments with Invisalign® require the use of attachments, which are composite resin buttons attached to tooth surfaces. Attachments constitute one of the most powerful tools for improving the efficiency of orthodontic tooth movement. The main purpose of this study was to evaluate surface wear over six months in two resin composites (Filtek Z350 XT, 3MESPE and Amelogen Plus TW, Ultradent Products Inc. ) used for making Invisalign® attachments. These composites were selected for their esthetic and mechanical properties...
August 2017: Acta Odontológica Latinoamericana: AOL
https://www.readbyqxmd.com/read/29244957/hypercementosis-associated-with-enpp1-mutations-and-gaci
#16
V Thumbigere-Math, A Alqadi, N I Chalmers, M B Chavez, E Y Chu, M T Collins, C R Ferreira, K FitzGerald, R I Gafni, W A Gahl, K S Hsu, M S Ramnitz, M J Somerman, S G Ziegler, B L Foster
Mineralization of bones and teeth is tightly regulated by levels of extracellular inorganic phosphate (Pi) and pyrophosphate (PPi). Three regulators that control pericellular concentrations of Pi and PPi include tissue-nonspecific alkaline phosphatase (TNAP), progressive ankylosis protein (ANK), and ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1). Inactivation of these factors results in mineralization disorders affecting teeth and their supporting structures. This study for the first time analyzed the effect of decreased PPi on dental development in individuals with generalized arterial calcification of infancy (GACI) due to loss-of-function mutations in the ENPP1 gene...
December 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29238380/static-and-kinetic-frictional-forces-of-silica-insert-ceramic-brackets-with-coated-archwires-in-artificial-saliva
#17
Mostafa Shahabi, Soheil Salari, Maryam Poosti, Mostafa Abtahi
Background: During sliding mechanics, the frictional force (FF) is an important counterforce to orthodontic tooth movement. The purpose of this in vitro study was to investigate the static and kinetic FFs of S silica-insert ceramic (SIC) brackets with Teflon-coated (TC) and conventional S stainless steel (SS) archwires. Materials and Methods: The target group of this study included 80 maxillary canine 0.022 inch slot SIC brackets. Forty SS brackets were used as the control...
November 2017: Dental Research Journal
https://www.readbyqxmd.com/read/29234742/tooth-movement-with-elastic-separators-before-ceramic-veneer-treatment-rearranging-asymmetric-diastemas-by-managing-the-horizontal-distance
#18
Leonardo Fernandes da Cunha, Brenda Procopiak Gugelmin, Ubiracy Gaião, Carla Castiglia Gonzaga, Gisele Maria Correr
The treatment of diastemas should be conservative to preserve tooth structure, and porcelain veneers provide an esthetic solution with minimal tooth preparation. However, asymmetric diastemas can be difficult to treat and may require redistribution of spaces. Additionally, extensive proximal restorations may negatively impact periodontal health. Minor tooth movement with elastic separators can be used to redistribute the interdental spaces and provide space for the interdental papilla. The aim of this paper was to present a clinical treatment involving the movement of peg-shaped maxillary lateral incisors with elastic separators to rearrange the spaces of asymmetric diastemas, thereby managing the horizontal distance during rehabilitation of the smile with minimally invasive ceramic veneers...
December 11, 2017: Quintessence International
https://www.readbyqxmd.com/read/29224185/tension-force-induced-bone-formation-in-orthodontic-tooth-movement-via-modulation-of-the-gsk-3%C3%AE-%C3%AE-catenin-signaling-pathway
#19
Yelin Mao, Liangliang Wang, Ye Zhu, Yu Liu, Hongwei Dai, Jianping Zhou, Dechun Geng, Lin Wang, Yong Ji
Orthodontic force-induced osteogenic differentiation and bone formation at tension sites play a critical role in orthodontic tooth movement. However, the molecular mechanism underlying this phenomenon is poorly understood. In the current study, we investigated the involvement of the GSK-3β/β-catenin signaling pathway, which is critical for bone formation during tooth movement. We established a rat tooth movement model to test the hypothesis that orthodontic force may stimulate bone formation at the tension site of the moved tooth and promote the rate of tooth movement via regulation of the GSK-3β/β-catenin signaling pathway...
December 9, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/29212478/effect-of-butorphanol-midazolam-or-ketamine-on-romifidine-based-sedation-in-horses-during-standing-cheek-tooth-removal
#20
Theresa Maria Müller, Klaus Hopster, Astrid Bienert-Zeit, Karl Rohn, Sabine B R Kästner
BACKGROUND: Standing surgery, especially dental procedures, are commonly performed in horses. This leads to an increasing demand for reliable sedation protocols. Therefore, it was the purpose of this study to investigate the influence of butorphanol, midazolam or ketamine on romifidine based sedation in horses during cheek tooth removal. METHODS: Forty horses presented for tooth extraction were divided in four groups using matched pair randomization. Group R was sedated with romifidine (bolus 0...
December 6, 2017: BMC Veterinary Research
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