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Text messaging randomized controlled trials

Charles Kaboré, Valéry Ridde, Séni Kouanda, Ludovic Queuille, Paul-André Somé, Isabelle Agier, Alexandre Dumont
BACKGROUND: Since 2006, Burkina Faso has subsidized the cost of caesarean sections to increase their accessibility. Caesareans are performed by obstetricians, general practitioners, and nurses trained in emergency surgery. While the national caesarean rate is still too low (only 2 % in 2010), 12 to 24 % of caesareans performed in hospital are, in fact, not medically indicated. The objective of this study is to evaluate the effectiveness and analyze the implementation of a multi-faceted intervention to lower the rate of non-medically indicated caesareans in Burkina Faso...
October 21, 2016: BMC Pregnancy and Childbirth
Julie Redfern, Karla Santo, Genevieve Coorey, Jay Thakkar, Maree Hackett, Aravinda Thiagalingam, Clara K Chow
INTRODUCTION: Many studies have now demonstrated the efficacy of text messaging in positively changing behaviours. We aimed to identify features and factors that explain the effectiveness of a successful text messaging program in terms of user engagement, perceived usefulness, behavior change and program delivery preferences. METHODS: Mixed methods qualitative design combining four data sources; (i) analytic data extracted directly from the software system, (ii) participant survey, (iii) focus groups to identify barriers and enablers to implementation and mechanisms of effect and (iv) recruitment screening logs and text message responses to examine engagement...
2016: PloS One
Katharine B Simmons, Alison B Edelman, Rongwei Fu, Jeffrey T Jensen
OBJECTIVE: The etonogestrel (ENG) subdermal implant can cause frequent breakthrough bleeding in some users. The objective of this study was to evaluate whether a short course of tamoxifen reduces bleeding/spotting days compared to placebo in ENG implant users. STUDY DESIGN: In this double-blind trial, we randomized ENG implant users with frequent or prolonged bleeding or spotting to tamoxifen 10 mg or placebo twice daily for seven days, to be started after three consecutive days of bleeding/spotting...
October 7, 2016: Contraception
Sheana Bull, Sharon Devine, Sara J Schmiege, Leslie Pickard, Jon Campbell, Judith C Shlay
OBJECTIVES: To consider whether Youth All Engaged! (a text message intervention) intensified the effects of the adolescent pregnancy prevention Teen Outreach Program (control) for youths. METHODS: In this trial performed in Denver, Colorado, from 2011 to 2014, we randomized 8 Boys & Girls Clubs each of 4 years into 32 clubs per year combinations to ensure each club would serve as a treatment site for 2 years and a control site for 2 years. Control intervention consisted of the Teen Outreach Program only...
September 2016: American Journal of Public Health
Rebecca E Guilkey, Claire B Draucker, Jingwei Wu, Zhangsheng Yu, Kurt Kroenke
INTRODUCTION: Persistent musculoskeletal pain is a prevalent, disabling, and often undertreated condition. This paper examines the acceptability of a telecare intervention for this condition. METHODS: The Stepped Care to Optimize Pain Care Effectiveness (SCOPE) intervention couples automatic symptom monitoring (ASM) with optimized analgesic care management by a nurse-physician team. Data from participants in the telecare intervention arm (n = 124) of a randomized control trial of SCOPE were analysed to determine the acceptability of the telecare intervention as indicated by patient use and satisfaction...
September 27, 2016: Journal of Telemedicine and Telecare
Niteesh K Choudhry, Thomas Isaac, Julie C Lauffenburger, Chandrasekar Gopalakrishnan, Nazleen F Khan, Marianne Lee, Amy Vachon, Tanya L Iliadis, Whitney Hollands, Scott Doheny, Sandra Elman, Jacqueline M Kraft, Samrah Naseem, Joshua J Gagne, Cynthia A Jackevicius, Michael A Fischer, Daniel H Solomon, Thomas D Sequist
BACKGROUND: Approximately half of patients with chronic cardiometabolic conditions are nonadherent with their prescribed medications. Interventions to improve adherence have been only modestly effective because they often address single barriers to adherence, intervene at single points in time, or are imprecisely targeted to patients who may not need adherence assistance. OBJECTIVE: To evaluate the effect of a multicomponent, behaviorally tailored pharmacist-based intervention to improve adherence to medications for diabetes, hypertension, and hyperlipidemia...
October 2016: American Heart Journal
Dvora Joseph Davey, José António Nhavoto, Orvalho Augusto, Walter Ponce, Daila Traca, Alexandre Nguimfack, Cesar Palha de Sousa
OBJECTIVE: We evaluated whether regular mobile phone text reminders improved patients' retention in antiretroviral therapy (ART) care in Mozambique. DESIGN: SMSaúde was a randomized control trial of HIV-infected patients on ART who received regular text message reminder vs. standard of care at 3 public health facilities in Maputo Province, Mozambique. The primary outcome was retention in HIV care. Between November 2011 and March 2012, 830 eligible HIV-infected patients on ART were randomized 1:1 to the text reminder intervention or standard of care...
October 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Ingrid V Bassett, Sharon M Coleman, Janet Giddy, Laura M Bogart, Christine E Chaisson, Douglas Ross, Margo M Jacobsen, Marion Robine, Tessa Govender, Kenneth A Freedberg, Jeffrey N Katz, Rochelle P Walensky, Elena Losina
BACKGROUND: A fraction of HIV-diagnosed individuals promptly initiate antiretroviral therapy (ART). We evaluated the efficacy of health system navigators for improving linkage to HIV and tuberculosis (TB) care among newly diagnosed HIV-infected outpatients in Durban, South Africa. METHODS: We conducted a randomized controlled trial (Sizanani Trial, NCT01188941) among adults (≥18 years) at 4 sites. Participants underwent TB screening and randomization into a health system navigator intervention or usual care...
October 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Maria Trent, Shang-En Chung, Charlotte Gaydos, Kevin D Frick, Jennifer Anders, Steven Huettner, Richard Rothman, Arlene Butz
PURPOSE: Pelvic inflammatory disease (PID) disproportionately affects adolescent and young adult (AYA) women and can negatively influence reproductive health trajectories. Few randomized controlled trials (RCTs) have focused on strategies to improve outpatient adherence or to reduce reproductive morbidity in this population. This paper describes the research methods and preliminary effectiveness of recruitment, retention, and intervention strategies employed in a novel RCT designed to test a technology-enhanced community-health nursing (TECH-N) intervention among urban AYA with PID...
August 2016: Eur Med J Reprod Health
Severin Haug, Raquel Paz Castro, Tobias Kowatsch, Andreas Filler, Michelle Dey, Michael P Schaub
Objective: To test the efficacy of a combined web- and text messaging-based intervention to reduce problem drinking in young people compared to assessment only. Method: Two-arm, parallel-group, cluster-randomized controlled trial with assessments at baseline and 6-month follow up. The automated intervention included online feedback, based on the social norms approach, and individually tailored text messages addressing social norms, outcome expectations, motivation, self-efficacy, and planning processes, provided over 3 months...
September 8, 2016: Journal of Consulting and Clinical Psychology
Carol E Golin, Kevin Knight, Jessica Carda-Auten, Michele Gould, Jennifer Groves, Becky L White, Steve Bradley-Bull, Kemi Amola, Niasha Fray, David L Rosen, Michael J Mugavaro, Brian W Pence, Patrick M Flynn, David Wohl
BACKGROUND: Policy-makers promote a seek, test, treat and retain (STTR) strategy to expand HIV testing, support linkage and engagement in care, and enhance the continuous use of antiretroviral therapy for those HIV-infected. This HIV prevention strategy is particularly appropriate in correctional settings where HIV screening and treatment are routinely available yet many HIV-infected individuals have difficulty sustaining sufficient linkage and engagement in care, disease management, and viral suppression after prison release...
2016: BMC Public Health
Fred Stephen Sarfo, Frank Treiber, Carolyn Jenkins, Sachin Patel, Mulugeta Gebregziabher, Arti Singh, Osei Sarfo-Kantanka, Raelle Saulson, Lambert Appiah, Eunice Oparebea, Bruce Ovbiagele
BACKGROUND: Hypertension is the premier modifiable risk factor for recurrent stroke. In sub-Saharan Africa (SSA) where the stroke burden is escalating, little is known about the role of behavioral interventions in enhancing blood pressure (BP) control after stroke. Our objective is to test whether an m-Health technology-enabled, nurse-led, multilevel integrated approach is effective in improving BP control among Ghanaian stroke patients within 1 month of symptom onset compared with standard of care...
2016: Trials
Dickson Shey Nsagha, Innocent Lange, Peter Nde Fon, Jules Clement Nguedia Assob, Elvis Asangbeng Tanue
BACKGROUND: HIV and AIDS are major public health problems in the world and Africa. In Cameroon, the HIV prevalence is 5.1%. Cellphones have been found to be useful in the provision of modern health care services using short message services (SMS). This study assessed the effectiveness of SMS in improving the adherence of people living with HIV and AIDS to their treatment and care in Cameroon. METHODS: This intervention study used a randomized controlled trial design...
2016: Open AIDS Journal
Li Chen, Xiaozhen Du, Lin Zhang, Michelle Helena van Velthoven, Qiong Wu, Ruikan Yang, Ying Cao, Wei Wang, Lihui Xie, Xiuqin Rao, Yanfeng Zhang, Jeanne Catherine Koepsell
BACKGROUND: The aim of this study was to assess the effectiveness of an EPI smartphone application (EPI app) on improving vaccination coverage in rural Sichuan Province, China. METHODS: This matched-pair cluster randomized controlled study included 32 village doctors, matched in 16 pairs, and took place from 2013 to 2015. Village doctors in the intervention group used the EPI app and reminder text messages while village doctors in the control group used their usual procedures and text messages...
2016: BMC Public Health
Angus G K McNair, Rhiannon C Macefield, Natalie S Blencowe, Sara T Brookes, Jane M Blazeby
PURPOSE: The CONSORT extension for patient reported outcomes (PROs) aims to improve reporting, but guidance on the optimal integration with clinical data is lacking. This study examines in detail the reporting of PROs and clinical data from randomized controlled trials (RCTs) in gastro-intestinal cancer to inform design and reporting of combined PRO and clinical data from trials to improve the 'take home' message for clinicians to use in practice. MATERIALS AND METHODS: The case study was undertaken in gastro-intestinal cancer trials...
2016: PloS One
Emma Cotten, Harry Prapavessis
BACKGROUND: Sedentary behavior (SB) has been linked to many health problems such as type 2 diabetes and heart disease. Increasing the length and frequency of breaks from sitting and increasing the time spent standing and engaged in light and moderate physical activity are ways to decrease SB. Text message-based interventions have succeeded in aiding smoking cessation and increase both physical activity and healthy eating, but they have not been shown to reduce SB. OBJECTIVE: The primary purpose of this pilot study was to determine the effectiveness of a text message-based intervention in increasing nonsedentary behaviors in university students...
2016: JMIR MHealth and UHealth
Yanhui Liao, Qiuxia Wu, Jinsong Tang, Fengyu Zhang, Xuyi Wang, Chang Qi, Haoyu He, Jiang Long, Brian C Kelly, Joanna Cohen
BACKGROUND: Considering the extreme shortage of smoking cessation services in China, and the acceptability, feasibility and efficacy of mobile phone-based text message interventions for quitting smoking in other countries, here we propose a study of "the efficacy of mobile phone-based text message interventions ('Happy Quit') for smoking cessation in China". The primary objective of this proposed project is to assess whether a program of widely accessed mobile phone-based text message interventions ('Happy Quit') will be effective at helping people in China who smoke, to quit...
2016: BMC Public Health
Brooke T Nezami, Leslie A Lytle, Deborah F Tate
BACKGROUND: Obesity in young children remains a public health concern, and maternal weight is one of the strongest predictors of obesity in early childhood. However, parental adherence in interventions for young children is often low and existing programs have had mixed success. An innovative approach to treatment is needed that increases adherence among mothers and improves weight-related behaviors simultaneously in mothers and children. The objective of the Smart Moms randomized controlled trial (RCT) is to test the efficacy of a 6-month primarily smartphone-delivered program to reduce sugar-sweetened beverage and juice consumption among children ages 3-5 whose mothers are overweight or obese...
2016: BMC Public Health
Ke Yang, Ling Jin, Li Li, Siming Zeng, Ruqian Wei, Guirong Li, Pingyi Man, Nathan Congdon
Importance: Follow-up after trabeculectomy surgery is important to surgical success, but little is known about the effect of interventions on improving follow-up in low-resource areas. Objective: To examine whether text message reminders and free eye medications improve follow-up after trabeculectomy in rural southern China. Design, Setting, and Participants: This randomized clinical trial studied 222 consecutive patients undergoing trabeculectomy from October 1, 2014, through November 31, 2015, at 4 rural hospitals in Guangdong and Guangxi Provinces, China...
October 1, 2016: JAMA Ophthalmology
Natascha Wagner, Denis Ouedraogo, Luis Artavia-Mora, Arjun Bedi, Boundia Alexandre Thiombiano
BACKGROUND: Retention in care and adherence to antiretroviral therapy (ART) among people living with human immunodeficiency virus (PLHIV) is a critical challenge in many African countries including Burkina Faso. Delivering text messaging (short message service, SMS) interventions through mobile phones may help facilitate health service delivery and improve patient health. Despite this potential, no evaluations have been delivered for national scale settings to demonstrate the impact of mobile health (mHealth) for PLHIV...
2016: JMIR Research Protocols
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