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Text messaging randomized controlled trials

Natalie Koch Levy, Natasha A Orzeck-Byrnes, Sneha R Aidasani, Dana N Moloney, Lisa H Nguyen, Agnes Park, Lu Hu, Aisha T Langford, Binhuan Wang, Mary Ann Sevick, Erin S Rogers
BACKGROUND: The Mobile Insulin Titration Intervention (MITI) program helps patients with type 2 diabetes find their correct basal insulin dose without in-person care. Requiring only basic cell phone technology (text messages and phone calls), MITI is highly accessible to patients receiving care in safety-net settings. MITI was shown in a randomized controlled trial (RCT) to be efficacious at a New York City (NYC) safety-net clinic where patients often have challenges coming for in-person care...
March 19, 2018: Journal of Medical Internet Research
Judd B Kessler, Andrea B Troxel, David A Asch, Shivan J Mehta, Noora Marcus, Raymond Lim, Jingsan Zhu, William Shrank, Troyen Brennan, Kevin G Volpp
BACKGROUND: Poor medication adherence is common and limits the effectiveness of treatment. OBJECTIVE: To investigate how social supports, automated alerts, and their combination improve medication adherence. DESIGN: Four-arm, randomized clinical trial with a 6-month intervention. PARTICIPANTS: A total of 179 CVS health employees or adult dependents with CVS Caremark prescription coverage, a current daily statin prescription, a medication possession ratio less than 80%, and Internet access...
March 15, 2018: Journal of General Internal Medicine
Eleni M Rettig, Carole Fakhry, Russell K Hales, Flora Kisuule, Harry Quon, Ana P Kiess, Linda X Yin, Yuehan Zhang, Amanda L Blackford, M Bradley Drummond, Christine G Gourin, Wayne M Koch, David W Eisele, Gypsyamber D'Souza
BACKGROUND: Smoking among patients with cancer is associated with poor outcomes, however, smoking cessation interventions have had limited success. METHODS: This randomized controlled trial compared a novel smoking cessation intervention ("intervention") with enhanced usual care ("control"). Participants were smokers with head and neck or thoracic malignancies undergoing radiation. Controls received brief counseling. Intervention participants received intensive counseling, pharmacotherapy, text-messaging, and financial incentives...
March 15, 2018: Head & Neck
Marisa E Hilliard, Sahar S Eshtehardi, Charles G Minard, Rana Saber, Debbe Thompson, Lefkothea P Karaviti, Yuliana Rojas, Barbara J Anderson
BACKGROUND: Supportive parent involvement for adolescents' type 1 diabetes (T1D) self-management promotes optimal diabetes outcomes. However, family conflict is common and can interfere with collaborative family teamwork. Few interventions have used explicitly strengths-based approaches to help reinforce desired management behaviors and promote positive family interactions around diabetes care. OBJECTIVE: The aim of this protocol was to describe the development of a new, strengths-based behavioral intervention for parents of adolescents with T1D delivered via a mobile-friendly Web app called Type 1 Doing Well...
March 13, 2018: JMIR Research Protocols
Mette Tranberg, Bodil Hammer Bech, Jan Blaakær, Jørgen Skov Jensen, Hans Svanholm, Berit Andersen
BACKGROUND: Cervical cancer screening participation remains insufficient in most countries. Our aim was to evaluate whether offering a HPV self-sampling kit, either mailed directly to the woman's home or using timely opt-in procedures for ordering the kit, increased screening participation compared with a standard second reminder. METHODS: In this randomized, controlled effectiveness trial, 9791 Danish women aged 30-64 who were due to receive the second reminder were equally randomized to either: 1) direct mailing of a second reminder and a self-sampling kit (directly mailed group); 2) mailing of a second reminder that offered a self-sampling kit to be ordered by e-mail, text message, phone, or webpage (opt-in group); or 3) mailing of a second reminder to attend regular cytology screening (control group)...
March 9, 2018: BMC Cancer
Abdul Momin Kazi, Murtaza Ali, Khurram Zubair, Hussain Kalimuddin, Abdul Nafey Kazi, Saleem Perwaiz Iqbal, Jean-Paul Collet, Syed Asad Ali
BACKGROUND: Improved routine immunization (RI) coverage is recommended as the priority public health strategy to decrease vaccine-preventable diseases and eradicate polio in Pakistan and worldwide. OBJECTIVE: The objective of this study was to ascertain whether customized, automated, one-way text messaging (short message service, SMS) reminders delivered to caregivers via mobile phones when a child is due for an RI visit can improve vaccination uptake and timelines in Pakistan...
March 7, 2018: JMIR Public Health and Surveillance
Maria Faurholt-Jepsen
Major reasons for the insufficient effects of current treatment options in bipolar disorder include delayed intervention for prodromal depressive and manic symptoms and decreased adherence to psychopharmacological treatment. The reliance on subjective information and clinical evaluations when diagnosing and assessing the severity of depressive and manic symptoms calls for less biased and more objective markers. By using electronic devices, fine-grained data on complex psychopathological aspects of bipolar disorder can be evaluated unobtrusively over the long term...
March 2018: Danish Medical Journal
Katerina A Christopoulos, Elise D Riley, Adam W Carrico, Jacqueline Tulsky, Judith T Moskowitz, Samantha Dilworth, Lara S Coffin, Leslie Wilson, Jason Johnson Peretz, Joan F Hilton
Background: Text messaging is a promising strategy to support HIV care engagement, but little is known about its efficacy in urban safety-net HIV clinic populations. Methods: We conducted a randomized controlled trial of a supportive and motivational text messaging intervention, Connect4Care (C4C), among viremic patients who had a history of poor retention or were new to clinic. Participants were randomized (stratified by new HIV diagnosis status) to receive one of the following for 12 months: 1) thrice-weekly intervention messages, plus texted primary care appointment reminders and a monthly text message requesting confirmation of study participation, or; 2) texted reminders and monthly messages alone...
February 21, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Chén C Kenyon, Siobhan M Gruschow, William O Quarshie, Heather Griffis, Michelle C Leach, Joseph J Zorc, Tyra C Bryant-Stephens, Victoria A Miller, Chris Feudtner
OBJECTIVE: To assess the feasibility of a mobile health, inhaled corticosteroid (ICS) adherence reminder intervention and to characterize adherence trajectories immediately following severe asthma exacerbation in high-risk urban children with persistent asthma. METHODS: Children aged 2-13 with persistent asthma were enrolled in this pilot randomized controlled trial during an asthma emergency department (ED) visit or hospitalization. Intervention arm participants received daily text message reminders for 30 days, and both arms received electronic sensors to measure ICS use...
February 13, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
Ahmed Hassoon, Jennifer Schrack, Daniel Naiman, Dina Lansey, Yasmin Baig, Vered Stearns, David Celentano, Seth Martin, Lawrence Appel
BACKGROUND: Physical activity has established health benefits, but motivation and adherence remain challenging. OBJECTIVE: We designed and launched a three-arm randomized trial to test artificial intelligence technology solutions to increase daily physical activity in cancer survivors. METHODS: A single-center, three-arm randomized clinical trial with an allocation ration of 1:1:1: (A) control, in which participants are provided written materials about the benefits of physical activity; (B) text intervention, where participants receive daily motivation from a fully automated, data-driven algorithmic text message via mobile phone (Coachtext); and (C) Voice Assist intervention, where participants are provided with an in-home on demand autonomous Intelligent Agent using data driven Interactive Digital Voice Assist on the Amazon Alexa/Echo (MyCoach)...
February 12, 2018: JMIR Research Protocols
Katherine L Downing, Jo Salmon, Trina Hinkley, Jill A Hnatiuk, Kylie D Hesketh
BACKGROUND: Despite public health guidelines to limit sedentary behavior, many young children spend large amounts of time sedentary (eg, screen and sitting time) during waking hours. OBJECTIVE: The objective of this study was to test the feasibility and efficacy of a parent-focused, predominantly text message-delivered intervention to support parents to reduce the amount of time their children spend in sedentary behavior. METHODS: Mini Movers was a pilot randomized controlled trial delivered to parents of 2- to 4-year-old children in Melbourne, Australia...
February 9, 2018: JMIR MHealth and UHealth
Richard Fletcher, Chris May, John Attia, Craig Franklin Garfield, Geoff Skinner
BACKGROUND: Recent estimates indicating that approximately 10% of fathers experience Paternal Perinatal Depression (PPND) and the increasing evidence of the impact of PPND on child development suggest that identifying and assisting distressed fathers is justified on public health grounds. However, addressing new fathers' mental health needs requires overcoming men's infrequent contact with perinatal health services and their reluctance to seek help. Text-based interventions delivering information and support have the potential to reach such groups in order to reduce the impact of paternal perinatal distress and to improve the wellbeing of their children...
February 6, 2018: JMIR Research Protocols
Spencer D Hawkins, Sarah B Koch, Phillip M Williford, Steven R Feldman, Daniel J Pearce
BACKGROUND: Consent and wound care (WC) videos are used for education in Mohs micrographic surgery (MMS). Postoperative text messaging is poorly studied. OBJECTIVE: Develop and evaluate perioperative resources for MMS patients-video modules ( and postoperative text messaging ( MATERIALS AND METHODS: A study was conducted on 90 MMS patients. Patients were randomized 1:1:1:1 to videos with text messages, videos-only, text messages-only, or control...
February 5, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Marzieh Araban, Zahra Karimian, Zohre Karimian Kakolaki, Karen A McQueen, Cindy-Lee Dennis
OBJECTIVE: To determine the effects of a prenatal breastfeeding self-efficacy intervention on breastfeeding self-efficacy and breastfeeding outcomes. DESIGN: Randomized controlled trial. SETTING: Four health centers in Ahvaz, Iran. PARTICIPANTS: A total of 120 low-risk, nulliparous women between 35 and 37 weeks gestation who intended to breastfeed their singleton infants. METHODS: Women were randomly assigned to receive the breastfeeding self-efficacy intervention (n = 60) or standard care (n = 60)...
January 31, 2018: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
Jin Lee, Tae Oh Kim, Joo Wan Seo, Joon Hyuk Choi, Nae Yun Heo, Jongha Park, Seung Ha Park, Sung Yeon Yang, Young Soo Moon
BACKGROUND/AIMS: Adequate bowel preparation is essential for an effective and safe colonoscopy. This study aimed to evaluate the quality of bowel preparation according to waiting times from education to colonoscopy. MATERIALS AND METHODS: A prospective, investigator-blinded, randomized study was performed from December 2016 to March 2017. Patients were divided into two groups: within 2 weeks (group A, n=64) or more than 2 weeks (group B, n=66) from education about bowel preparation to colonoscopy...
January 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
Thomas A Odeny, Maricianah Onono, Kevin Owuor, Anna Helova, Iris Wanga, Elizabeth A Bukusi, Janet M Turan, Lisa L Abuogi
BACKGROUND: Successful completion and retention throughout the multi-step cascade of prevention of mother-to-child HIV transmission (PMTCT) remains difficult to achieve. The Mother and Infant Visit Adherence and Treatment Engagement study aims to evaluate the effect of mobile text messaging, community-based mentor mothers (cMMs), or both on increasing antiretroviral therapy (ART) adherence, retention in HIV care, maternal viral load suppression, and mother-to-child HIV transmission for mother-infant pairs receiving lifelong ART...
January 29, 2018: Trials
Shu Chen, Enying Gong, Dhruv S Kazi, Ann B Gates, Rong Bai, Hua Fu, Weixia Peng, Ginny De La Cruz, Lei Chen, Xianxia Liu, Qingjie Su, Nicolas Girerd, Kamilu M Karaye, Khalid F Alhabib, Lijing L Yan, J D Schwalm
BACKGROUND: Coronary heart disease (CHD) is the leading cause of cardiovascular mortality worldwide, yet implementation of evidence-based strategies for secondary prevention remains suboptimal. OBJECTIVE: This study aimed to evaluate the feasibility, specifically the usability and acceptability, and estimate the preliminary effectiveness of a mobile health (mHealth) intervention targeting both physicians and patients to improve adherence to evidence-based medications and lifestyle modifications...
January 25, 2018: JMIR MHealth and UHealth
Ralph Maddison, Ralph Stewart, Rob Doughty, Tony Scott, Andrew Kerr, Jocelyne Benatar, Robyn Whittaker, Jonathan C Rawstorn, Anna Rolleston, Yannan Jiang, Paul Estabrooks, Rachel Karen Sullivan, Hannah Bartley, Leila Pfaeffli Dale
BACKGROUND: Cardiac rehabilitation (CR) is an essential component of contemporary management for patients with coronary heart disease, including following an acute coronary syndrome (ACS). CR typically involves education and support to assist people following an ACS to make lifestyle changes and prevent subsequent events. Despite its benefits, uptake and participation in tradition CR programs is low. The use of mobile technologies (mHealth) offers the potential to improve reach, access, and delivery of CR support...
January 25, 2018: Trials
Michael H Bernstein, L A R Stein, Clayton Neighbors, Brian Suffoletto, Kate B Carey, Ginette Ferszt, Nicole Caron, Mark D Wood
Twenty-first birthdays are associated with extreme levels of heavy drinking and alcohol-related harm. Effective preventive interventions that are acceptable to young adults are needed. The current study tested the efficacy of a brief text-message intervention for reducing 21st birthday alcohol involvement designed to correct perceived 21st birthday drinking norms and provide protective behavioral strategies (PBS). We also examined potential moderators and mediators. College students (n = 200) with an upcoming 21st birthday completed a baseline assessment and were randomized to a text-message intervention or an assessment-only control condition...
January 25, 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
Andrew E Levy, Carrie Huang, Allen Huang, P Michael Ho
PURPOSE OF REVIEW: Non-adherence to medications for the secondary prevention of myocardial infarction (MI) is a major contributor to morbidity and mortality in these patients. This review describes recent advances in promoting adherence to therapies for coronary artery disease (CAD). RECENT FINDINGS: Two large randomized controlled trials to "incentivize" adherence were somewhat disappointing; neither financial incentives nor "peer pressure" successfully increased rates of adherence in the post-MI population...
January 24, 2018: Current Atherosclerosis Reports
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