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https://www.readbyqxmd.com/read/29893469/leadership-and-registered-nurses-rns-working-after-hours-in-residential-aged-care-facilities-racfs-a-structured-literature-review
#1
REVIEW
Dorika Nhongo, Joyce Hendricks, Julie Bradshaw, Kasia Bail
BACKGROUND: Registered nurses (RNs) working in Residential Aged Care Facilities are required to undertake complex management tasks including leading nursing care teams, supervising non-nursing staff, and allocating workloads according to residents' care needs, staff skills and experience. Registered nurses plan, assess, manage medication, evaluate each resident's care, liaise with doctors and allied health professionals and are responsible for evidence-based practice in accordance with the Nursing Standards for Practice (2016)...
June 12, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29792124/hypersensitivity-to-alemtuzumab-a-safe-and-effective-desensitization-protocol-a-case-report
#2
Diego Gutiérrez-Fernández, Mónica Saldaña-Valderas, Raquel de la Varga-Martínez, Antonio Foncubierta-Fernández, María J Fernández-Anguita, Maria Del C Fernández-Valle, Fermín Medina-Varo
We describe a successful desensitization to alemtuzumab in one patient diagnosed with T-cell prolymphocytic leukaemia. Alemtuzumab treatment was initiated during infusion number 18, the patient showed cutaneous eruption with a miliary pattern, despite premedication with corticosteroids and antihistamines. The eruption returned with successive alemtuzumab infusions (infusions 19, 20 and 21), remained present for longer and was more severe with each infusion. The patient was referred to our Allergy Unit as it was necessary to maintain alemtuzumab treatment...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29786029/academics-anonymous-a-medical-student-s-12-step-guide-to-scholarly-productivity
#3
Nissi Wei, James A Bourgeois, Ana Hategan, Amin Azzam
An important aspect of academic medicine is publication in peer-reviewed journals and other media. Early scholarly productivity in medical school may jump-start a successful academic career. Topic choice, search methodology, writing strategies, mentorship, and collaboration are all fundamental to successful academic productivity. The authors reviewed the importance of instituting the germinal stages of scholarly productivity during medical training and created 12 steps for facilitating productive academic writing by students...
September 2017: Education for Health: Change in Training & Practice
https://www.readbyqxmd.com/read/29730987/stigma-associated-with-medication-treatment-for-young-adults-with-opioid-use-disorder-a-case-series
#4
Scott E Hadland, Tae Woo Park, Sarah M Bagley
BACKGROUND: Opioid-related overdose deaths have risen sharply among young adults. Despite this increase, access to evidence-based medication for opioid agonist treatment (OAT) for youth remains low. Among older adults, barriers to OAT include the paucity of buprenorphine-waivered prescribers and low rates of prescribing among waivered physicians. We have increasingly found in our clinical practice significant stigma related to using OAT to treat addiction for young adults. In this series, we describe three cases of young adults who faced significant stigma related to their treatment...
May 7, 2018: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29611891/a-unified-approach-for-the-assembly-of-atisine-and-hetidine-type-diterpenoid-alkaloids-total-syntheses-of-azitine-and-the-proposed-structure-of-navirine-c
#5
Jie Liu, Dawei Ma
A tetracyclic dinitrile was synthesized in twelve steps from cyclohex-2-en-1-one by using a chelation-triggered conjugate addition to a γ-hydroxy-substituted α,β-unsaturated nitrile and an oxidative dearomatization/Diels-Alder cycloaddition cascade as the key steps. The first total synthesis of azitine (in 17 steps) was achieved through a simple reductive cyclization of this intermediate and subsequent transformations while the total synthesis of the proposed structure of navirine C (in 19 steps) was accomplished by a hydrogen-atom-transfer reaction of the tetracyclic dinitrile, Pd/C-catalyzed reductive cyclization, and subsequent functional group manipulation...
April 3, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29606223/a-longitudinal-study-of-the-comparative-efficacy-of-women-for-sobriety-lifering-smart-recovery-and-12-step-groups-for-those-with-aud
#6
Sarah E Zemore, Camillia Lui, Amy Mericle, Jordana Hemberg, Lee Ann Kaskutas
BACKGROUND: Despite the effectiveness of 12-step groups, most people reporting a prior alcohol use disorder (AUD) do not sustain involvement in such groups at beneficial levels. This highlights the need for research on other mutual help groups that address alcohol problems and may attract those who avoid 12-step groups. The current study addresses this need, offering outcome data from the first longitudinal, comparative study of 12-step groups and their alternatives: The Peer ALlternatives for Addiction (PAL) Study...
May 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29596724/a-randomized-controlled-trial-of-a-gender-focused-addiction-model-versus-12-step-facilitation-for-women-veterans
#7
Lisa M Najavits, Justin Enggasser, Deborah Brief, Edward Federman
BACKGROUND AND OBJECTIVES: Substance use disorder (SUD) has increased among women, including military veterans, yet SUD treatment was historically designed for males. This randomized controlled trial compared 12 individual sessions of a gender-focused SUD recovery model, A Woman's Path to Recovery (WPR) to an evidence-based, non-gender-focused SUD model, 12-Step Facilitation (TSF) for 66 women veterans with current severe SUD. METHODS: The primary outcome was substance use; secondary outcomes were associated problems (e...
April 2018: American Journal on Addictions
https://www.readbyqxmd.com/read/29596216/reduction-of-inappropriate-antimicrobial-prescriptions-in-a-tertiary-neonatal-intensive-care-unit-following-antimicrobial-stewardship-care-bundle-implementation
#8
Joseph Y Ting, Vanessa Paquette, Karen Ng, Sarka Lisonkova, Valoria Hait, Sandesh Shivanada, Peter Tilley, Osiovich Horacio, Ashley Roberts
BACKGROUND: Our objective was to evaluate the appropriateness of antibiotic prescriptions in the neonatal intensive care unit (NICU) using standardised criteria and determine the effects of an antimicrobial stewardship programme (ASP) on patterns of antibiotic usage. METHODS: A retrospective audit of antibiotic use from July 2010-June 2013 was conducted, focusing on prescriptions of vancomycin, cefotaxime, meropenem and linezolid for >3 calendar days. We evaluated the appropriateness of each course of antibiotic treatment based on the Centers for Disease Control and Prevention (CDC) 12-Step Guidelines to Prevent Antimicrobial Resistance (Steps 4, 6 and 9)...
March 24, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29498250/breast-cancer-effectiveness-of-a-one-year-unsupervised-exercise-program
#9
Gabriele Mascherini, Benedetta Tosi, Chiara Giannelli, Elisabetta Grifoni, Sonia Degl'innocenti, Giorgio Galanti
BACKGROUND: Improvements in prevention and therapeutic strategies over the years have increased the numbers of breast cancer survivors considerably. Sedentary behavior is now acknowledged to be a risk factor for cancer and cancer relapse. Currently, there are different approaches to increasing the effectiveness of long-term physical activity in these patients. The aim of this study was to verify the long-term effectiveness of a home-based program for active lifestyle change in overweight breast cancer survivors...
March 1, 2018: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29483035/burnout-is-associated-with-emotional-intelligence-but-not-traditional-job-performance-measurements-in-surgical-residents
#10
Kevin D Cofer, Robert H Hollis, Lauren Goss, Melanie S Morris, John R Porterfield, Daniel I Chu
OBJECTIVE: To evaluate whether burnout was associated with emotional intelligence and job performance in surgical residents. DESIGN: General surgery residents at a single institution were surveyed using the Maslach Burnout Inventory (MBI) and trait EI questionnaire (TEIQ-SF). Burnout was defined as scoring in 2 of the 3 following domains; Emotional Exhaustion (high), Depersonalization (high), and Personal Accomplishment (low). Job performance was evaluated using faculty evaluations of clinical competency-based surgical milestones and standardized test scores including the American Board of Surgery In-Training Exam (ABSITE) and the United States Medical Licensing Examination (USMLE) Step 3...
February 23, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29371119/how-to-perform-a-systematic-review-and-meta-analysis-of-diagnostic-imaging-studies
#11
REVIEW
Paul Cronin, Aine Marie Kelly, Duaa Altaee, Bradley Foerster, Myria Petrou, Ben A Dwamena
A systematic review is a comprehensive search, critical evaluation, and synthesis of all the relevant studies on a specific (clinical) topic that can be applied to the evaluation of diagnostic and screening imaging studies. It can be a qualitative or a quantitative (meta-analysis) review of available literature. A meta-analysis uses statistical methods to combine and summarize the results of several studies. In this review, a 12-step approach to performing a systematic review (and meta-analysis) is outlined under the four domains: (1) Problem Formulation and Data Acquisition, (2) Quality Appraisal of Eligible Studies, (3) Statistical Analysis of Quantitative Data, and (4) Clinical Interpretation of the Evidence...
January 19, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29356553/formal-synthesis-of-codeine-by-application-of-temporary-thio-derivatization
#12
Julia Rautschek, Anne Jäger, Peter Metz
Desymmetrization of a p-quinone monoacetal by organocatalytic sulfa-Michael addition provided rapid access to a C-ring building block for a formal synthesis of (-)-codeine. By means of a diastereoselective 1,2-addition for A/C-ring union, an intramolecular nitrone cycloaddition for construction of the phenanthrene core, and a sulfoxide elimination, an enantiopure key intermediate of the authors' previous synthesis of racemic codeine was available in 12 steps from isovanillin.
February 2, 2018: Organic Letters
https://www.readbyqxmd.com/read/29340423/total-synthesis-of-five-natural-eremophilane-type-sesquiterpenoids
#13
Zhe Meng, Bo Liu
The first total syntheses of five natural eremophilane-type sesquiterpenoids were achieved in 4-12 steps via a common synthetic intermediate. The syntheses feature a double Michael addition, Robinson annulation, α-enolization of an unsaturated ketone, and Pd-catalyzed Suzuki coupling reaction to install the side chain. This synthetic strategy could be easily extended to other eremophilane-type sesquiterpenoids with similar bicyclic skeletons.
February 7, 2018: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29281282/concise-synthesis-of-natural-phenylphenalenone-phytoalexins-and-a-regioisomer
#14
Ming-Zhong Wang, Chuen-Fai Ku, Tong-Xu Si, Siu-Wai Tsang, Xiao-Meng Lv, Xiao-Wan Li, Zheng-Ming Li, Hong-Jie Zhang, Albert S C Chan
Concise total syntheses of the natural phytoalexins 2-hydroxy-8-(4-hydroxyphenyl)phenalen-1-one (1), 2-hydroxy-8-(3,4-dihydroxyphenyl)phenalen-1-one (2), and hydroxyanigorufone (4), together with regioisomer 3 are accomplished in 11 or 12 steps. The synthetic strategy features a Friedel-Crafts acylation to construct the 1H-phenalen-1-one tricyclic core followed by a Suzuki cross-coupling to obtain the target compounds.
January 26, 2018: Journal of Natural Products
https://www.readbyqxmd.com/read/29195590/age-differences-in-outcomes-among-patients-in-the-stimulant-abuser-groups-to-engage-in-12-step-stage-12-intervention
#15
Sharon B Garrett, Suzanne R Doyle, K Michelle Peavy, Elizabeth A Wells, Mandy D Owens, Kathy Shores-Wilson, Jessica DiCenzo, Dennis M Donovan
Emerging adults (roughly 18-29years) with substance use disorders can benefit from participation in twelve-step mutual-help organizations (TSMHO), however their attendance and participation in such groups is relatively low. Twelve-step facilitation therapies, such as the Stimulant Abuser Groups to Engage in 12-Step (STAGE-12), may increase attendance and involvement, and lead to decreased substance use. AIMS: Analyses examined whether age moderated the STAGE-12 effects on substance use and TSMHO meeting attendance and participation...
January 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29176448/patients-experiences-of-using-a-cellular-photo-digital-breathalyzer-for-treatment-purposes
#16
Christina Nehlin, Kristina Carlsson, Caisa Öster
OBJECTIVES: The field of eHealth systems is rapidly developing and is now expanding into alcohol treatment settings. Despite a growing public and professional interest, cellular photo digital breathalyzers (CPDBs) have not been investigated in a clinical context so far. In this study, we aimed to investigate the experiences of patients in alcohol treatment who had been using a CPDB-TripleA- for a minimum of three months. What are their personal experiences of using the CPDB? Do the patients think it supports them to change their drinking habits, and if so, in what way? METHODS: A qualitative interview study with individuals who had been using the CPDB TripleA, for at least 3 months as complement to treatment (12-step program or hospital-based outpatient care)...
March 2018: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29135783/beyond-the-bottom-of-the-foot-topographic-organization-of-the-foot-dorsum-in-walking
#17
Taryn Klarner, Gregory E P Pearcey, Yao Sun, Trevor S Barss, Chelsea Kaupp, Bridget Munro, Nick Frank, E Paul Zehr
INTRODUCTION: Sensory feedback from the foot dorsum during walking has only been studied globally by whole nerve stimulation. Stimulating the main nerve innervating the dorsal surface produces a functional stumble corrective response that is phase-dependently modulated. We speculated that effects evoked by activation of discrete skin regions on the foot dorsum would be topographically organized, as with the foot sole. METHODS: Nonnoxious electrical stimulation was delivered to five discrete locations on the dorsal surface of the foot during treadmill walking...
December 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29057032/decreased-drinking-and-alcoholics-anonymous-are-associated-with-different-dimensions-of-spirituality
#18
Amy R Krentzman, Stephen Strobbe, J Irene Harris, Jennifer M Jester, Elizabeth A R Robinson
Alcoholics Anonymous (AA) is a spiritual program and involvement in it has been associated with increases in spirituality. Some who pursue recovery outside AA also use spirituality for support. Decreasing drinking without AA involvement might result in spiritual change, but this has not been explored in previous research. This study investigates drinking and AA behavior to determine their association with seven dimensions of subsequent spirituality. METHODS: A 30-month panel study recruited 364 individuals with alcohol dependence...
September 2017: Psychology of Religion and Spirituality
https://www.readbyqxmd.com/read/29048974/strengthening-the-working-alliance-through-a-clinician-s-familiarity-with-the-12-step-approach
#19
Cory B Dennis, Brian D Roland, Barry M Loneck
BACKGROUND: The working alliance plays an important role in the substance use disorder treatment process. Many substance use disorder treatment providers incorporate the 12-Step approach to recovery into treatment. With the 12-Step approach known among many clients and clinicians, it may well factor into the therapeutic relationship. OBJECTIVE: We investigated how, from the perspective of clients, a clinician's level of familiarity with and in-session time spent on the 12-Step approach might affect the working alliance between clients and clinicians, including possible differences based on a clinician's recovery status...
2018: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29038678/posttraumatic-growth-and-recovery-from-addiction
#20
Eyal Haroosh, Sara Freedman
Background : It is well documented that individuals coping with adverse events report both negative outcomes, such as posttraumatic stress symptoms, as well as positive changes, described as posttraumatic growth. Positive changes are also reported in people who have recovered from substance abuse. It seems plausible from the literature that both of these types of positive changes have elements in common. To date, no published studies have examined positive outcomes among people who have recovered from addiction...
2017: European Journal of Psychotraumatology
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