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https://www.readbyqxmd.com/read/29332114/dental-arch-dimensions-form-and-tooth-size-ratio-among-a-saudi-sample
#1
Haidi Omar, Manar Alhajrasi, Nayef Felemban, Ali Hassan
To determine the dental arch dimensions and arch forms in a sample of Saudi orthodontic patients, to investigate the prevalence of Bolton anterior and overall tooth size discrepancies, and to compare the effect of gender on the measured parameters. Methods: This study is a biometric analysis of dental casts of 149 young adults recruited from different orthodontic centers in Jeddah, Saudi Arabia. The dental arch dimensions were measured. The measured parameters were arch length, arch width, Bolton's ratio, and arch form...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29330673/vacuum-assisted-closure-therapy-of-paradoxical-reaction-in-tuberculous-lymphadenopathy-caused-by-mycobacterium-africanum
#2
H F Geerdes-Fenge, P Pongratz, J Liese, E C Reisinger
A 26-year-old HIV-negative male from Ghana was treated for cervical, intrathoracic and abdominal lymph node tuberculosis (TB) and tuberculous hepatitis. Penetration of the thoracic trachea by a mediastinal lymph node had caused bronchomucosal TB. Sputum culture grew M. africanum, sensitive to all first-line antituberculous drugs. Four weeks after the beginning of directly observed treatment with isoniazid, rifampin, pyrazinamide and ethambutol, the right cervical lymph node increased in size, liquefied and caused a spontaneous fistula...
January 12, 2018: Infection
https://www.readbyqxmd.com/read/29328327/realizable-design-of-field-taper-via-coordinate-transformation
#3
Jianjia Yi, Sawyer D Campbell, Rui Feng, Shah Nawaz Burokur, Douglas H Werner
Complex electromagnetic structures can be designed by exploiting the concept of spatial coordinate transformations. In this paper, we define a coordinate transformation scheme that enables one to taper the electric field between two waveguides of different cross-sections. The electromagnetic field launched from the wide input waveguide is compressed in the proposed field tapering device and guided into the narrow output waveguide. In closed rectangular waveguide configurations, the taper can further play the role of a mode selector due to the output waveguide's cut-off frequency...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29328324/temperature-insensitive-optical-fiber-strain-sensor-with-ultra-low-detection-limit-based-on-capillary-taper-temperature-compensation-structure
#4
Changpeng Lang, Yi Liu, Kunjian Cao, Shiliang Qu
An optical fiber strain sensor based on capillary-taper compensation structure was proposed. The theoretical simulation by using the finite element analysis method shows a matching condition between the capillary length and the interference-cavity length to achieve the zero temperature crosstalk. Meanwhile, the strain sensitivity can also be improved greatly at the matching condition. We then set up an insertion controller system with high accuracy to make sure the interference-cavity length can match the capillary length...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29328320/efficient-and-tunable-strip-to-slot-fundamental-mode-coupling
#5
Viphretuo Mere, Rakshitha Kallega, Shankar Kumar Selvaraja
We present a novel photonic wire-to-slot waveguide coupler in SOI. The phase matching between a wire and slot mode is achieved using a mode transformer. The architecture consists of a balanced 50/50 power splitter and a tunable phase matched taper combiner forming a slot waveguide. We show a theoretical wire-to-slot coupling efficiency of 99 % is achievable and experimentally, we demonstrate a coupling efficiency of 99 % in the 1550 nm band. Based on the coupling scheme, we also show excitation of a slot mode in a slotted ring resonator and verified the excitation through the thermo-optic response of the rings...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29328303/tunable-and-channel-spacing-precisely-controlled-comb-filters-based-on-the-fused-taper-technology
#6
Mengmeng Han, Xingliang Li, Shumin Zhang, Huiyun Han, Jingmin Liu, Zhenjun Yang
We propose and demonstrate an adjustable all-fiber comb filter with precisely controlled channel spacing by employing a tapered fiber in one arm of a Mach-Zehnder interferometer (MZI) for the first time. Using fused taper technology to draw the fiber, we can precisely control the optical path difference between the two arms of the MZI, thus realizing a precisely controllable channel spacing. By rotating the polarization controller state in the other arm of the MZI, the transmission spectrum wavelength can be continuously tuned...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29326307/mycophenolate-mofetil-in-combination-with-steroids-for-treatment-of-c3-glomerulopathy-a-case-series
#7
Rupali S Avasare, Pietro A Canetta, Andrew S Bomback, Maddalena Marasa, Yasar Caliskan, Yasemin Ozluk, Yifu Li, Ali G Gharavi, Gerald B Appel
BACKGROUND AND OBJECTIVES: C3 glomerulopathy is a form of complement-mediated GN. Immunosuppressive therapy may be beneficial in the treatment of C3 glomerulopathy. Mycophenolate mofetil is an attractive treatment option given its role in the treatment of other complement-mediated diseases and the results of the Spanish Group for the Study of Glomerular Diseases C3 Study. Here, we study the outcomes of patients with C3 glomerulopathy treated with steroids and mycophenolate mofetil. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a retrospective chart review of patients in the C3 glomerulopathy registry at Columbia University and identified patients treated with mycophenolate mofetil for at least 3 months and follow-up for at least 1 year...
January 11, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29325166/drug-safety-and-immunogenicity-of-tumour-necrosis-factor-inhibitors-the-story-so-far
#8
Meghna Jani, William G Dixon, Hector Chinoy
TNF-α inhibitor (TNFi) therapies have transformed the treatment of several rheumatic musculoskeletal diseases. However, the majority of TNFi's are immunogenic and consequent anti-drug antibodies formation can impact on both treatment efficacy and safety. Several controversies exist in the area of immunogenicity of TNFis and drug safety. While anti-drug antibodies to TNFis have been described in association with infusion reactions; serious adverse events (AEs) such as thromboembolic events, lupus-like syndrome, paradoxical AEs, for example, vasculitis-like events and other autoimmune manifestations have also been reported...
January 8, 2018: Rheumatology
https://www.readbyqxmd.com/read/29324473/chondromyxoid-fibroma-arising-in-craniofacial-sites-a-clinicopathologic-analysis-of-25-cases
#9
David M Meredith, Christopher D M Fletcher, Vickie Y Jo
Chondromyxoid fibroma (CMF) is a rare benign tumor, usually arising in the metaphysis of long bones in young adults. Occurrence in craniofacial bones presents a particular diagnostic challenge given its unusual location and resemblance to malignant mimics. We describe the clinicopathologic features of 25 cases of craniofacial CMF identified between 1999 and 2017. Patients were 14 men and 11 women, with median age of 44 years (range, 5 to 83 y). Sites of involvement were sphenoid (7), ethmoid (5), maxilla (3), occipital (2), nasal septum (2), palatine (2), temporal (2), orbit (1), and undisclosed skull (1)...
January 10, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29321813/novel-concept-of-a-modular-hip-implant-could-contribute-to-less-implant-failure-in-tha-a-hypothesis
#10
Ronny Grunert, Stefan Schleifenbaum, Robert Möbius, Michael Kopper, Christian Rotsch, Welf-Guntram Drossel, Niels Hammer, Torsten Prietzel
Background: The modularity in total hip arthroplasty (THA) allows orthopaedic surgeons for an exact reconstruction of hip biomechanical parameters especially in revision and tumor arthroplasty. Modular structured femoral stems using taper junctions showed increased implant breakage in the recent past. Presentation of the hypothesis: We hypothesize that a novel modular stem-neck-interface leads to less implant breakage compared to conventional femoral stems. Testing of the hypothesis: For this purpose, a novel modular femoral stem for THA was to design and manufacture...
2018: Patient Safety in Surgery
https://www.readbyqxmd.com/read/29321467/importance-of-regular-and-maintenance-therapy-adherence-in-neuromyelitis-optica-nmo-lessons-from-a-repeating-relapse-case
#11
Jing Miao, Doreen E Aboagye, Boris Chulpayev, Lin Liu, Gary Ishkanian, Bangaruraju Kolanuvada, Dariush Alaie, Richard L Petrillo
BACKGROUND Neuromyelitis optica (NMO) is a rare demyelinating disease of the central nervous system; NMO predominantly affects the spinal cord and optic nerves. The diagnosis is based on history, clinical presentation, seropositive NMO-IgG antibody, and notably, exclusion of other diseases. Despite the absence of definitive therapeutic strategies for NMO, methylprednisolone pulse therapy and plasma exchange are used for acute phase treatment, while immunosuppressive agent(s) are recommended to prevent relapses and improve prognosis...
January 11, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29321427/cardiac-sarcoidosis-concomitant-with-large-vessel-aortitis-detected-by-18f-fluorodeoxyglucose-positron-emission-tomography
#12
Yoshihiro Higuchi, Yasutaka Kimoto, Rika Tanoue, Tomotake Tokunou, Kenichiro Tomonari, Toyoki Maeda, Takahiko Horiuchi
We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat the recurrence of cardiac sarcoidosis...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29320974/head-to-head-comparison-of-adverse-effects-and-efficacy-between-high-dose-deflazacort-and-high-dose-prednisolone-in-systemic-lupus-erythematosus-a-prospective-cohort-study
#13
A Ganapati, R Ravindran, T David, B Yadav, V Jeyaseelan, L Jeyaseelan, D Danda
Background Deflazacort (DFZ), an oxazoline derivative of prednisolone (PDN), has a dose equivalence of 1.2:1 (mg) to PDN. No study to date has compared adverse effects and efficacy of high doses of DFZ as against high-dose PDN in systemic lupus erythematosus (SLE). Objectives To compare adverse effects of high dose DFZ and PDN in SLE patients, especially in terms of cushingoid features and gain in body weight, 3 and 6 months after initiation of these agents. Methods In both the steroid arms, the following outcome parameters were assessed at 3 and 6 months: (a) cushingoid features by Cushing's Severity Index (CSI) (b) hirsutism by modified Ferriman Gallwey score (c) weight gain by difference (Δ, delta) of weight (in kilograms)...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29320845/subcutaneous-administration-of-tocilizumab-is-effective-in-myointimal-hyperplasia-remodelling-in-refractory-takayasu-arteritis
#14
A Lo Gullo, G Mandraffino, C O Aragona, A Molica Colella, A Saitta, E Imbalzano
Takayasu arteritis (TA) is a chronic inflammatory disease of unknown origin that involves large and mediumsized arteries, primarily the aorta and its major branches. TA is a therapeutic challenge because corticosteroids and conventional immunosuppressive agents are not always effective or safe. Interleukin 6 (IL-6) has emerged as a key cytokine in the pathogenesis of TA and its serum levels have been shown to well correlate with disease activity. We report a 19 years old female patient with TA refractory to conventional immunosuppressive agents, successfully treated with subcutaneous tocilizumab, a humanized monoclonal antibody against IL-6 receptor, in which ultrasonography (US) was used as imaging tool to follow up the patient...
December 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/29320823/first-blindness-cases-of-horses-infected-with-setaria-digitata-nematoda-filarioidea-in-the-republic-of-korea
#15
Jihun Shin, Kyu-Sung Ahn, Guk-Hyun Suh, Ha-Jung Kim, Hak-Sub Jeong, Byung-Su Kim, Eunsang Choi, Sung-Shik Shin
Ocular setariases of cattle were reported but those of equine hosts have never been reported in the Republic of Korea (Korea). We found motile worms in the aqueous humor of 15 horses (Equus spp.) from 12 localities in southern parts of Korea between January 2004 and November 2017. After the affected animals were properly restrained under sedation and local anesthesia, 10 ml disposable syringe with a 16-gauge needle was inserted into the anterior chamber of the affected eye to successfully remove the parasites...
December 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/29320598/eruptive-sebaceous-hyperplasia-a-rare-consequence-of-systemic-corticosteroids
#16
Geraldine Cheyana Ranasinghe, Adam J Friedman
BACKGROUND: Eruptive sebaceous hyperplasia is a rare and poorly understood consequence of immunosuppression, most commonly with cyclosporine, following organ transplantation. To date, there have been no reports documenting eruptive sebaceous hyperplasia associated with the utilization of immunosuppression outside of this clinical scenario. OBSERVATION: A 43-year-old Caucasian male with a significant history for Crohn's disease presented with the sudden appearance of multiple asymptomatic growths now present for several weeks...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29319895/the-onset-of-fretting-at-the-head-stem-connection-in-hip-arthroplasty-is-affected-by-head-material-and-trunnion-design-under-simulated-corrosion-conditions
#17
Fiachra E Rowan, Amanda Wach, Timothy M Wright, Douglas E Padgett
Mechanically assisted crevice corrosion (MACC) is a mechanism for trunnion damage in total hip arthroplasties (THAs). Retrieval studies have shown reduced MACC-related damage for ceramic heads compared with cobalt-chromium (CoCr) heads. We propose that ceramic heads demonstrate fretting at higher cyclic compressive loads than CoCr heads on titanium alloy trunnions in a simulated corrosion model. A closed electrochemical chamber was used to measure fretting current onset loads for two modern titanium alloy trunnions (Zimmer 12/14 and Stryker V-40) in which trunnion failure has been reported...
January 10, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29316668/joint-high-order-synchrosqueezing-transform-and-multi-taper-empirical-wavelet-transform-for-fault-diagnosis-of-wind-turbine-planetary-gearbox-under-nonstationary-conditions
#18
Yue Hu, Xiaotong Tu, Fucai Li, Guang Meng
Wind turbines usually operate under nonstationary conditions, such as wide-range speed fluctuation and time-varying load. Its critical component, the planetary gearbox, is prone to malfunction or failure, which leads to downtime and repair costs. Therefore, fault diagnosis and condition monitoring for the planetary gearbox in wind turbines is a vital research topic. Meanwhile, the signals measured by the vibration sensors mounted in the gearbox exhibit time-varying and nonstationary features. In this study, a novel time-frequency method based on high-order synchrosqueezing transform (SST) and multi-taper empirical wavelet transform (MTEWT) is proposed for the wind turbine planetary gearbox under nonstationary conditions...
January 7, 2018: Sensors
https://www.readbyqxmd.com/read/29314738/long-term-efficacy-and-safety-of-add-on-tacrolimus-for-persistent-active-rheumatoid-arthritis-despite-treatment-with-methotrexate-and-tumor-necrosis-factor-inhibitors
#19
Taio Naniwa, Shiho Iwagaitsu, Mikiko Kajiura
AIM: To assess the long-term efficacy and safety of adding tacrolimus for patients with active rheumatoid arthritis (RA) despite anti-tumor necrosis factor (TNF) therapy with methotrexate. METHODS: Consecutive patients who were treated with adding tacrolimus onto anti-TNF therapy with methotrexate for active RA despite anti-TNF therapy with methotrexate, were retrospectively analyzed in terms of treatment response, achieving remission, subsequent treatment tapering and adverse events...
January 4, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29314271/potassium-iodide-in-refractory-recurrent-pediatric-sweet-syndrome-guidance-in-dosing-and-monitoring
#20
Jennifer Aileen Ang Tangtatco, Nhung Ho, Aaron Drucker, Catherine Forse
We describe a 5-month-old boy with clinical and histopathologic presentation of Sweet syndrome. He responded to systemic corticosteroids, with multiple flares on tapering; potassium iodide was added, which provided complete resolution of Sweet syndrome. Potassium iodide has been used in only a few cases, and no standard dosage has been established in children. We discuss calculation of a pediatric dosage for potassium iodide in Sweet syndrome.
January 4, 2018: Pediatric Dermatology
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