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Conciousness

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https://www.readbyqxmd.com/read/27319093/-anesthesia-and-consciousness
#1
Yuichi Ogino, Hiroaki Kawamichi, Shigeru Saiot
The mechanism of consciousness and loss of conciousness by general anesthetics are crucial issue for the anesthesiologists. Recent non-invasive brain-imaging technology brings about light to various our emotions and sensations in human brain; however, neural correlate of consciousness is not yet still elucidated. The concept "the seat of the consciousness (is in the subcortical nuclei)" is now completely denied, but instead the consciousness is based on the idea that connectivity and communications across cortical and thalamocortical networks...
May 2016: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/27066766/infusion-of-low-dose-glyceryl-trinitrate-has-no-consistent-effect-on-burrowing-behavior-running-wheel-activity-and-light-sensitivity-in-female-rats
#2
Sarah L T Christensen, Steffen Petersen, Dorte B Sørensen, Jes Olesen, Inger Jansen-Olesen
INTRODUCTION: Glyceryl trinitrate induces headache during infusion to man and migraine patients develop an additional migraine attack a few hours after the infusion. Recently, we have moved this model into rat with the intention of developing an animal model predictive of migraine therapy. In the current paper we have studied the effect of glyceryl trinitrate infusion on three different rat behaviors. METHODS: The stability of burrowing behavior, running wheel activity and light sensitivity towards repeated testing was evaluated also with respect to estrous cycle...
July 2016: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/26143337/consciousness-cognition-and-brain-networks-new-perspectives
#3
E M Aldana, J L Valverde, N Fábregas
A detailed analysis of the literature on consciousness and cognition mechanisms based on the neural networks theory is presented. The immune and inflammatory response to the anesthetic-surgical procedure induces modulation of neuronal plasticity by influencing higher cognitive functions. Anesthetic drugs can cause unconsciousness, producing a functional disruption of cortical and thalamic cortical integration complex. The external and internal perceptions are processed through an intricate network of neural connections, involving the higher nervous activity centers, especially the cerebral cortex...
October 2016: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/26051131/-inequalities-in-cervical-screening-practices
#4
REVIEW
Lajos Döbrőssy, Attila Kovács, András Budai
Theoretically, the cytology-based cervical screening is capable of early detection of precancerous epithelial lesions of cervix uteri and its cancer, and of early referral to treatment. In this way, screening can inmprove the quality of life of the patients and reduce mortality from the target disease. Unfortunately, this often remains unexploited, because there might be inequalities on both "supply" and "demand" side of screening. In addition to the geopolitical situation of a country, inequalities might result from differences in the health care systems, and heavy access to the screening services...
June 14, 2015: Orvosi Hetilap
https://www.readbyqxmd.com/read/26011771/identification-and-characterization-of-near-fatal-asthma-phenotypes-by-cluster-analysis
#5
MULTICENTER STUDY
J Serrano-Pariente, G Rodrigo, J A Fiz, A Crespo, V Plaza
BACKGROUND: Near-fatal asthma (NFA) is a heterogeneous clinical entity and several profiles of patients have been described according to different clinical, pathophysiological and histological features. However, there are no previous studies that identify in a unbiased way--using statistical methods such as clusters analysis--different phenotypes of NFA. Therefore, the aim of the present study was to identify and to characterize phenotypes of near fatal asthma using a cluster analysis...
September 2015: Allergy
https://www.readbyqxmd.com/read/24754204/-gz-tolerance-with-and-without-muscle-tensing-following-loss-of-anti-g-trouser-pressure
#6
Alec T Stevenson, Jonathan P R Scott
BACKGROUND: Fast jet aircrew are heavily reliant on anti-G trousers (AGT) and failure of the garment or its pressure supply would expose them to high levels of +Gz acceleration without protection. A previous study demonstrated the severity of this event at high +Gz, but no data exists as to the maximum +Gz level which could be tolerated. METHODS: : While relaxed and with lower body muscle tensing, 10 experienced centrifuge subjects had their AGT deflated after 5 and 30 s of +Gz exposure...
April 2014: Aviation, Space, and Environmental Medicine
https://www.readbyqxmd.com/read/24670290/-the-role-of-shame-in-development-of-the-mental-disorders-i-theoretical-background
#7
REVIEW
Gabriella Vizin, Zsolt Unoka
Shame is a particularly intense, often incapacitating negative emotion involving feeling of inferiority, powerlessness and self-consciousness, along with the desire to hide or disappear. The experience of shame is an adaptive and natural reaction until it becomes a chronic and painful emotion as a result of environment and temperamental factors. According to studies of the last decade chronic shame is a central feature of the social interactions as well as of a variety of psychopathologies including anxiety disorders, depression, eating disorders, and personality disorders...
2014: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/24482970/atrial-myxoma-a-rare-cause-of-ischemic-stroke
#8
R C Negi, Vivek Chauhan, Brij Sharma, Rajeev Bhardwaj, Surinder Thakur
Arial myxoma can present as stroke and should be considered as a differential diagnosis of stroke in young individuals. We present here a 42 years female who presented with sudden loss of conciousness. After extensive work up for young stroke, left atrial myxoma was detected and tumor was removed surgically and histopathological report was consistent with the atrial myxoma.
April 2013: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/24458541/challenges-in-collecting-pharmacokinetic-and-pharmacodynamic-information-in-an-intensive-care-setting-pk-pd-modelling-of-clazosentan-in-patients-with-aneurysmal-subarachnoid-haemorrhage
#9
RANDOMIZED CONTROLLED TRIAL
Jochen Zisowsky, Eliane Fuseau, Shirin Bruderer, Andreas Krause, Jasper Dingemanse
PURPOSE: This paper describes the pharmacokinetic/pharmacodynamic modelling of clazosentan in patients with aneurysmal subarachnoid haemorrhage (aSAH), and the impact of collecting data in an intensive care unit (ICU) setting. Factors influencing data quality, analysis, and interpretation are provided with recommendations for future clinical studies in ICU settings. METHODS: CONSCIOUS-2 was a phase III study involving 1,157 patients with aSAH. Secured by surgical clipping, patients were infused with clazosentan or placebo for up to 14 days post-aSAH...
April 2014: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/24409653/nomenclature-and-basic-concepts-in-automation-in-the-clinical-laboratory-setting-a-practical-glossary
#10
REVIEW
Angelos A Evangelopoulos, Maria Dalamaga, Konstantinos Panoutsopoulos, Kleanthi Dima
In the early 80s, the word automation was used in the clinical laboratory setting referring only to analyzers. But in late 80s and afterwards, automation found its way into all aspects of the diagnostic process, embracing not only the analytical but also the pre- and post-analytical phase. While laboratories in the eastern world, mainly Japan, paved the way for laboratory automation, US and European laboratories soon realized the benefits and were quick to follow. Clearly, automation and robotics will be a key survival tool in a very competitive and cost-concious healthcare market...
2013: Clinical Laboratory
https://www.readbyqxmd.com/read/24331960/-a-cross-sectional-survey-on-the-efficacy-of-china-healthy-lifestyle-for-all-in-2012
#11
Yuan Li, Juan Zhang, Xiao-ming Shi, Xiao-feng Liang
OBJECTIVE: To study the efficacy of 'China Healthy Lifestyle for All' (CHLA). METHODS: Under similar GDP status, two counties(one with CHLA and one without)were randomly selected from each province of China. Cluster randomized sampling method was performed to select 500 over 18-year-olds from each county. Face-to-face questionnaire interview was used to collect data related to knowledge, awareness and behavior on healthy lifestyle. Generalized Estimated Equation was fitted for the multi-factor analysis...
September 2013: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/24311022/validity-and-reliability-of-the-cold-discomfort-scale-a-subjective-judgement-scale-for-the-assessment-of-patient-thermal-state-in-a-cold-environment
#12
Peter Lundgren, Otto Henriksson, Kalev Kuklane, Ingvar Holmér, Peter Naredi, Ulf Björnstig
Complementary measures for the assessment of patient thermoregulatory state, such as subjective judgement scales, might be of considerable importance in field rescue scenarios where objective measures such as body core temperature, skin temperature, and oxygen consumption are difficult to obtain. The objective of this study was to evaluate, in healthy subjects, the reliability of the Cold Discomfort Scale (CDS), a subjective judgement scale for the assessment of patient thermal state in cold environments, defined as test-retest stability, and criterion validity, defined as the ability to detect a difference in cumulative cold stress over time...
June 2014: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/24172773/rhinocerebral-mucormycosis-in-a-patient-with-type-1-diabetes-presenting-as-toothache-a-case-report-from-himalayan-region-of-india
#13
REVIEW
Vikram Singh, Mridu Singh, Chitra Joshi, Jyoti Sangwan
Mucormycosis is an angioinvasive infection caused by ubiquitous filamentous fungi of the order Mucorales. It is a rapidly progressive fatal infection mostly reported in susceptible individuals, such as those with poorly controlled diabetes or those with defects in phagocytic function. Rhinocerebral mucormycosis is the most common type of mucormycosis in diabetic patients. This case report describes a 17-year-old girl with type 1 diabetes mellitus presenting with rhinocerebral mucormycosis. The patient presented with a history of toothache and facial pain with oedema of left half of face, periorbital oedema and depressed conciousness...
2013: BMJ Case Reports
https://www.readbyqxmd.com/read/23152117/implementation-of-the-acr-dose-index-registry-at-a-large-academic-institution-early-experience
#14
COMPARATIVE STUDY
Tracy J Robinson, Jeffrey D Robinson, Kalpana M Kanal
A rising conciousness within both the medical community and in the public has been created by the current levels of radiation exposure from increased use of computed tomography. The concern has prompted the need for more data collection and analysis of hospital and imaging center exam doses. This has spurred the American College of Radiology (ACR) to develop the Dose Index Registry (DIR), which will allow participating insitutions to compare the radiation dose from their CT exams to aggregate national CT dose data based on exam type and body part...
April 2013: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/23056790/clinical-presentation-of-novel-influenza-a-h-1-n-1-in-hospitalized-children
#15
Gholamreza Soleimani, Marzieh Akbarpour
OBJECTIVE: Human pandemic influenza H(1)N(1) virus as the cause of febrile respiratory infection ranging from self-limited to severe illness has spread globally during 2009. Signs and symptoms of upper and lower respiratory tract involvement, fever, sore throat, rhinitis, myalgia, malaise, headache, chills and fatigue are common. In this article we report the clinical presentation of Influenza A (H(1)N(1)) in our hospitalized children. METHODS: Between September and October 2009, all children requiring hospitalization for suspected H(1)N(1) infection were transferred to Pediatric Infectious Diseases ward...
June 2011: Iranian Journal of Pediatrics
https://www.readbyqxmd.com/read/20597207/conciousness-remains-elusive
#16
EDITORIAL
Roman R Poznanski
No abstract text is available yet for this article.
June 2010: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/20442979/-carboxyhemoglobin-concentration-in-carbon-monoxide-poisoning-critical-appraisal-of-the-predictive-value
#17
REVIEW
L Köthe, J Radke
In cases of unclear depression of conciousness, arrhythmia and symptoms of cardiac insufficiency inadvertent carbon monoxide intoxication should always be taken into consideration. Rapid diagnosis of acute carbon monoxide intoxication with mostly unspecific symptoms requires an immediate supply of high dose oxygen which enables a distinct reduction of mortality and long-term morbidity. Levels of carboxyhemoglobin, however, should not be used as a parameter to decide whether to supply normobaric or the more efficient hyperbaric oxygen...
June 2010: Der Anaesthesist
https://www.readbyqxmd.com/read/20084923/-anthrax-meningoencephalitis-a-case-report-and-review-of-turkish-literature
#18
REVIEW
Gökhan Metan, Burcu Uysal, Ramazan Coşkun, Duygu Perçin, Mehmet Doğanay
The incidence of anthrax is decreasing in Turkey, however, it is still endemic in some regions of the country. Although central nervous system involvement is rare in cases with anthrax, high mortality rates are significant. Here, we report a 46-years old woman who was anthrax meningoencephalitis. The patient was from Yozgat located in Central Anatolia, Turkey. Her history revealed that following peeling the skin of sheeps and consuming their meat a week ago, a lesion developed in her left forearm and she had been treated with penicilin G with the diagnosis of cutaneous anthrax in a local health center...
October 2009: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/19679933/-non-convulsive-status-epilepticus-a-rare-but-important-reason-for-prolonged-loss-of-conciousness
#19
E Olafsson, T Magnusson
Non-convulsive status epilepticus is a rare form of epilepsy. The predominant clinical feature is prolonged loss of consciousness without prominent motor features. The diagnosis is often difficult because of the non-specific nature of the symptoms and this diagnostic possibility has to be born in mind when patients present with unexplained alteration in the level of consciousness, especially if there is a prior history of epilepsy. The electroencephalogram plays a key role in the diagnosis and intravenous administration of diazepam is a useful diagnostic test, especially in conjunction with EEG...
March 1997: Læknablađiđ
https://www.readbyqxmd.com/read/19544673/a-case-of-serotonin-syndrome-associated-with-methadone-overdose
#20
Terry T Martinez, Daniel N Martinez
A chronic pain patient prescribed 20 mg of methadone per day was seen at the Emergency Department within one hour following a witnessed intentional 200 mg ingestion. In addition, he was taking the serotonin re-uptake inhibitor antidepressant drugs, sertraline and venlafaxine as prescribed. Methadone is also a serotonin re-uptake inhibitor which has been involved in serotonin toxicity reactions. Initially, no symptoms of narcotic overdose (depressed central nervous system, respiration, or blood pressure) could be distinguished, and the standard narcotic urine screen was negative...
2008: Proceedings of the Western Pharmacology Society
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