Fadi Soukarieh, Alaa Mashabi, William Richardson, Eduard Vico Oton, Manuel Romero, Shaun N Roberston, Scott Grossman, Tomas Sou, Ruiling Liu, Nigel Halliday, Irena Kukavica-Ibrulj, Roger C Levesque, Christel A S Bergstrom, Barrie Kellam, Jonas Emsley, Stephan Heeb, Paul Williams, Michael J Stocks, Miguel Cámara
P. aeruginosa (PA) continues to pose a threat to global public health due to its high levels of antimicrobial resistance (AMR). The ongoing AMR crisis has led to an alarming shortage of effective treatments for resistant microbes, and hence there is a pressing demand for the development of novel antimicrobial interventions. The potential use of antivirulence therapeutics to tackle bacterial infections has attracted considerable attention over the past decades as they hamper the pathogenicity of target microbes with reduced selective pressure, minimizing the emergence of resistance...
September 10, 2021: ACS Infectious Diseases