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https://www.readbyqxmd.com/read/29351709/-validation-of-the-screening-for-complex-ptsd-skptbs-revision
#1
Florence Dorr, Martin Sack, Jürgen Bengel
BACKGROUND: The aim was to develop further a screening instrument for complex posttraumatic stress disorder (cPTSD). The screening for cPTSD (SkPTBS) tests a) potential traumatic experiences, b) influential features and risk factors, and c) symptoms of cPTSD. The SkPTBS by Dorr et al. (2016) was revised according to the current ICD-11 criteria set proposal for cPTSD and is explored in its revised edition. METHOD: Impacts of long-lasting interpersonal trauma were tested in inpatients of psychosomatic rehabilitation and in patients consulting a university outpatient center for trauma therapy...
January 19, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29351652/early-results-in-flow-diverter-sizing-by-computational-simulation-quantification-of-size-change-and-simulation-error-assessment
#2
Ana Paula Narata, Jordi Blasco, Luis San Roman, Juan Miguel Macho, Hector Fernandez, Raquel Kale Moyano, Renaud Winzenrieth, Ignacio Larrabide
BACKGROUND: Sizing of flow diverters (FDs) stent in the treatment of intracranial aneurysms is a challenging task due to the change of stent length after implantation. OBJECTIVE: To quantify the size change and assess the error in length prediction in 82 simulated FD deployments. METHODS: Eighty-two consecutive patients treated with FDs were retrospectively analyzed. Implanted FD length was measured from angiographic images and compared to the nominal sizes of the implanted device...
January 17, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29351612/a-mutational-signature-associated-with-alcohol-consumption-and-prognostically-significantly-mutated-driver-genes-in-esophageal-squamous-cell-carcinoma
#3
X C Li, M Y Wang, M Yang, H J Dai, B F Zhang, W Wang, X L Chu, X Wang, H Zheng, R F Niu, W Zhang, K X Chen
Background: Esophageal squamous cell carcinoma (ESCC) is often diagnosed at an advanced and incurable stage. Information on driver genes and prognosticators in ESCC remains incomplete. The objective was to elucidate significantly mutated genes (SMGs), mutational signatures, and prognosticators in ESCC. Patients and Methods: Three MutSig algorithms (i.e. MutSigCV, MutSigCL and MutSigFN) and "20/20+" ratio-metric were employed to identify SMGs. Nonnegative matrix factorization was used to decipher mutational signatures...
January 16, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29351250/a-gps-phase-locked-loop-performance-metric-based-on-the-phase-discriminator-output
#4
Stefan Stevanovic, Boris Pervan
We propose a novel GPS phase-lock loop (PLL) performance metric based on the standard deviation of tracking error (defined as the discriminator's estimate of the true phase error), and explain its advantages over the popular phase jitter metric using theory, numerical simulation, and experimental results. We derive an augmented GPS phase-lock loop (PLL) linear model, which includes the effect of coherent averaging, to be used in conjunction with this proposed metric. The augmented linear model allows more accurate calculation of tracking error standard deviation in the presence of additive white Gaussian noise (AWGN) as compared to traditional linear models...
January 19, 2018: Sensors
https://www.readbyqxmd.com/read/29351164/body-mass-index-versus-body-fat-percentage-in-prospective-nfl-athletes-overestimation-of-obesity-rate-in-athletes-at-the-nfl-scouting-combine
#5
Capt Matthew T Provencher, Jorge Chahla, George Sanchez, Mark E Cinque, Nicholas I Kennedy, Jim Whalen, Mark D Price, Gilbert Moatshe, Robert F LaPrade
Obesity has been previously noted as a major issue in the National Football League (NFL), where it has been shown that 97% of all players demonstrate a body mass index (BMI) of ≥25.0 with a reported obesity rate of 56% (BMI ≥30.0). However, BMI does not take into account body composition by mass, and may overestimate prevalence of obesity. The purposes of this study were to (1) determine the validity of BMI as a measure of body fat percentage and obesity in athletes at the NFL Combine, to define the obesity rate based on body fat percentage compared to BMI...
January 17, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29351077/molecular-and-morphological-characterisation-of-rhabdias-picardiae-junker-lhermitte-vallarino-et-bain-2010-nematoda-rhabdiasidae-from-delaland-s-river-frog-amietia-delalandii-dum%C3%A3-ril-et-bibron-1841-amphibia-pyxicephalidae-in-south-africa
#6
Roman Svitin, Yuriy Kuzmin, Louis du Preez
Rhabdias picardiae previously known from the Guttural Toad, Sclerophrys gutturalis (Bufonidae) is described from a new host, Delaland's River Frog, Amietia delalandii (Pyxicephalidae). The species identification is confirmed by analysis of the COI gene sequence and morphological comparison with the original description. Morphological details of apical structures in adult parasitic R. picardiae, namely, the shape and position of lips, the number and position of external labial papillae, and the buccal capsule morphology are described using light and scanning electron microscopy...
March 26, 2018: Acta Parasitologica
https://www.readbyqxmd.com/read/29350607/shaping-the-future-of-science-publishing-the-evolution-of-metrics
#7
Florian P Thomas, Carolann Murphy
No abstract text is available yet for this article.
January 19, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29350592/geographic-proximity-to-specialized-pediatric-neurosurgical-care-in-the-contiguous-united-states
#8
Abdul-Kareem Ahmed, Ann-Christine Duhaime, Timothy R Smith
OBJECTIVE Absent from an analysis of supply is consideration of the geographic distribution of pediatric neurosurgeons. Several patient socioeconomic metrics are known to be associated with outcome in pediatric neurosurgical diseases, such as hydrocephalus. The purpose of this study was to determine current geographic proximity to pediatric neurosurgical care using professional society databases. This study also sought to establish how socioeconomic factors are related to distance to care, using federal government-collected data...
January 19, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29350437/diffusion-tensor-imaging-mri-of-sickle-cell-kidney-disease-initial-results-and-comparison-with-iron-deposition
#9
Shannon B Donnola, Connie M Piccone, Lan Lu, Joshua Batesole, Jane Little, Katherine M Dell, Chris A Flask
Chronic kidney disease (CKD) occurs in over one-third of patients with sickle cell disease (SCD) and can progress to end-stage renal disease. Unfortunately, current clinical assessments of kidney function are insensitive to early-stage CKD. Previous studies have shown that diffusion magnetic resonance imaging (MRI) can sensitively detect regional renal microstructural changes associated with early-stage CKD. However, previous MRI studies in patients with SCD have been largely limited to the detection of renal iron deposition assessed by T2 * relaxometry...
January 19, 2018: NMR in Biomedicine
https://www.readbyqxmd.com/read/29350223/what-is-career-success-for-academic-hospitalists-a-qualitative-analysis-of-early-career-faculty-perspectives
#10
Ethan Cumbler, Essey Yirdaw, Patrick Kneeland, Read Pierce, Patrick Rendon, Carrie Herzke, Christine D Jones
BACKGROUND: Understanding the concept of career success is critical for hospital medicine groups seeking to create sustainably rewarding faculty positions. Conceptual models of career success describe both extrinsic (compensation and advancement) and intrinsic (career satisfaction and job satisfaction) domains. How hospitalists define career success for themselves is not well understood. In this study, we qualitatively explore perspectives on how early-career clinician-educators define career success...
January 19, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29350218/comparing-institution-nitrogen-footprints-metrics-for-assessing-and-tracking-environmental-impact
#11
Elizabeth A Castner, Allison M Leach, Jana E Compton, James N Galloway, Jennifer Andrews
When multiple institutions with strong sustainability initiatives use a new environmental impact assessment tool, there is an impulse to compare. The first seven institutions to calculate nitrogen footprints using the Nitrogen Footprint Tool have worked collaboratively to improve calculation methods, share resources, and suggest methods for reducing their footprints. This article compares those seven institutions' results to reveal the common and unique drivers of institution nitrogen footprints. The footprints were compared by scope and sector, and the results were normalized by multiple factors (e...
April 1, 2017: Sustainability (New Rochelle)
https://www.readbyqxmd.com/read/29350217/an-integrated-tool-for-calculating-and-reducing-institution-carbon-and-nitrogen-footprints
#12
Allison M Leach, James N Galloway, Elizabeth A Castner, Jennifer Andrews, Neil Leary, John D Aber
The development of nitrogen footprint tools has allowed a range of entities to calculate and reduce their contribution to nitrogen pollution, but these tools represent just one aspect of environmental pollution. For example, institutions have been calculating their carbon footprints to track and manage their greenhouse gas emissions for over a decade. This article introduces an integrated tool that institutions can use to calculate, track, and manage their nitrogen and carbon footprints together. It presents the methodology for the combined tool, describes several metrics for comparing institution nitrogen and carbon footprint results, and discusses management strategies that reduce both the nitrogen and carbon footprints...
April 1, 2017: Sustainability (New Rochelle)
https://www.readbyqxmd.com/read/29350191/a-prospective-gating-method-to-acquire-a-diverse-set-of-free-breathing-ct-images-for-model-based-4dct
#13
Dylan O'Connell, Dan Ruan, David H Thomas, Tai H Dou, John H Lewis, Anand P Santhanam, Percy P Lee, Daniel A Low
Breathing motion modeling requires observation of tissues at sufficiently distinct respiratory states for proper 4D characterization. This work proposes a method to improve sampling of the breathing cycle with limited imaging dose. We designed and tested a prospective free-breathing acquisition protocol with a simulation using datasets from 5 patients imaged with a model-based 4DCT technique. Each dataset contained 25 free-breathing fast helical CT scans with simultaneous breathing surrogate measurements...
January 19, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29350187/multifractal-dynamics-of-resting-state-functional-connectivity-in-the-prefrontal-cortex
#14
Frigyes Samuel Racz, Peter Mukli, Zoltan Nagy, Andras Eke
Brain function is organized as a network of functional connections between different neuronal populations with connection strengths dynamically changing in time and space. Studies investigating functional connectivity (FC) usually follow a static approach when describing FC by considering the connectivity strengths constant, however a dynamic approach seems more reasonable, as this way the spatio-temporal dynamics of the underlying system can also be captured. Objective: The scale-free, i.e. fractal nature of neural dynamics is an inherent property of the nervous system...
January 19, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29350181/a-single-continuous-metric-to-define-tiered-serum-neutralization-potency-against-hiv
#15
Peter Hraber, Bette Korber, Kshitij Wagh, David Montefiori, Mario Roederer
HIV-1 Envelope (Env) variants are grouped into tiers by their neutralization-sensitivity phenotype. This helped to recognize that tier-1 neutralization responses can be elicited readily, but do not protect against new infections. Tier-3 viruses are the least sensitive to neutralization. Because most circulating viruses are tier 2, vaccines that elicit neutralization responses against them are needed. While tier classification is widely used for viruses, a way to rate serum or antibody neutralization responses in comparable terms is needed...
January 19, 2018: ELife
https://www.readbyqxmd.com/read/29350082/quantitative-dti-metrics-in-a-canine-model-of-krabbe-disease-comparisons-versus-age-matched-controls-across-multiple-ages
#16
Jonathan Y Li, Dana M Middleton, Steven Chen, Leonard White, Carley R Corado, Charles Vite, Allison Bradbury, James M Provenzale
Purpose The purpose of this study was to compare quantitative diffusion tensor imaging metrics in dogs affected with a model of Krabbe disease to age-matched normal controls. We hypothesized that fractional anisotropy would be decreased and radial diffusivity would be increased in the Krabbe dogs. Methods We used a highly reproducible region-of-interest interrogation technique to measure fractional anisotropy and radial diffusivity in three different white matter regions within the internal capsule and centrum semiovale in four Krabbe affected brains and three age-matched normal control brains...
January 1, 2018: Neuroradiology Journal
https://www.readbyqxmd.com/read/29349952/estimation-of-cerebral-metabolic-rate-of-oxygen-consumption-using-combined-multiwavelength-photoacoustic-microscopy-and-doppler-microultrasound
#17
Yan Jiang, Roger Zemp
The metabolic rate of oxygen consumption is an important metric of tissue oxygen metabolism and is especially critical in the brain, yet few methods are available for measuring it. We use a custom combined photoacoustic-microultrasound system and demonstrate cerebral oxygen consumption estimation in vivo. In particular, the cerebral metabolic rate of oxygen consumption was estimated in a murine model during variation of inhaled oxygen from hypoxia to hyperoxia. The hypothesis of brain autoregulation was confirmed with our method even though oxygen saturation and flow in vessels changed...
January 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29349833/a-systematic-assessment-of-key-design-and-performance-characteristics-of-drug-exposure-registries-requested-by-the-u-s-food-and-drug-administration
#18
Yanling Zhao, Ellen Pinnow, Jacqueline M Major
PURPOSE: The purpose of the study is to evaluate contributions to postmarket safety assessments and identify potential factors for enhancing implementation and utilization of registries in regulatory decision-making. METHODS: Registry documents (e.g., protocols, reports) submitted to the FDA were identified up to January 2016 through an extensive, systematic review of internal records and resources. We characterized nonpregnancy drug exposure registries based on prespecified design elements, performance, and regulatory impact...
January 19, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29349566/performance-improvement-in-head-and-neck-cancer
#19
REVIEW
Carol M Lewis, Randal S Weber
Performance improvement requires establishing a platform to set benchmarks and monitor the quality of care provided through quality indicators and metrics. This has long been recognized as critical to overall quality improvement and more recently, has become federally mandated. Here, we review recent studies evaluating performance in head and neck cancer care, from those spanning all phases of head and neck cancer care to others focused on head and neck surgical performance, including both national and departmental/institutional efforts...
January 19, 2018: Current Oncology Reports
https://www.readbyqxmd.com/read/29349458/trends-in-adsorption-of-electrocatalytic-water-splitting-intermediates-on-cubic-abo3-oxides
#20
Joseph H Montoya, Andrew D Doyle, Jens K Nørskov, Aleksandra Vojvodic
The reactivity of solid oxide surfaces towards adsorption of oxygen and hydrogen is a key metric for the design of new catalysts for electrochemical water splitting. In this paper, we report on trends in the adsorption energy of different adsorbed intermediates derived from the oxidation and reduction of water for ternary ABO3 oxides in the cubic perovskite structure. Our findings support a previously reported trend that rationalizes the observed lower bound in oxygen evolution (OER) overpotentials from correlations in OH* and OOH* adsorption energies...
January 19, 2018: Physical Chemistry Chemical Physics: PCCP
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