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https://www.readbyqxmd.com/read/29232695/integrative-assessment-of-climate-change-for-fast-growing-urban-areas-measurement-and-recommendations-for-future-research
#1
Sebastian Scheuer, Dagmar Haase, Martin Volk
Over the 20th century, urbanization has substantially shaped the surface of Earth. With population rapidly shifting from rural locations towards the cities, urban areas have dramatically expanded on a global scale and represent crystallization points of social, cultural and economic assets and activities. This trend is estimated to persist for the next decades, and particularly the developing countries are expected to face rapid urban growth. The management of this growth will require good governance strategies and planning...
2017: PloS One
https://www.readbyqxmd.com/read/29232365/monitoring-compliance-with-standards-of-care-for-chronic-diseases-using-healthcare-administrative-databases-in-italy-strengths-and-limitations
#2
Rosa Gini, Martijn J Schuemie, Alessandro Pasqua, Emanuele Carlini, Francesco Profili, Iacopo Cricelli, Patrizio Dazzi, Valentina Barletta, Paolo Francesconi, Francesco Lapi, Andrea Donatini, Giulia Dal Co, Modesta Visca, Mariadonata Bellentani, Miriam Sturkenboom, Niek Klazinga
BACKGROUND: A recent comprehensive report on healthcare quality in Italy published by the Organization of Economic Co-operation and Development (OECD) recommended that regular monitoring of quality of primary care by means of compliance with standards of care for chronic diseases is performed. A previous ecological study demonstrated that compliance with standards of care could be reliably estimated on regional level using administrative databases. This study compares estimates based on administrative data with estimates based on GP records for the same persons, to understand whether ecological fallacy played a role in the results of the previous study...
2017: PloS One
https://www.readbyqxmd.com/read/29230232/chemosensitization-of-fusarium-graminearum-to-chemical-fungicides-using-cyclic-lipopeptides-produced-by-bacillus-amyloliquefaciens-strain-jck-12
#3
Kihyun Kim, Yoonji Lee, Areum Ha, Ji-In Kim, Ae Ran Park, Nan Hee Yu, Hokyoung Son, Gyung Ja Choi, Hae Woong Park, Chul Won Lee, Theresa Lee, Yin-Won Lee, Jin-Cheol Kim
Fusarium head blight (FHB) caused by infection with Fusarium graminearum leads to enormous losses to crop growers, and may contaminate grains with a number of Fusarium mycotoxins that pose serious risks to human and animal health. Antagonistic bacteria that are used to prevent FHB offer attractive alternatives or supplements to synthetic fungicides for controlling FHB without the negative effects of chemical management. Out of 500 bacterial strains isolated from soil, Bacillus amyloliquefaciens JCK-12 showed strong antifungal activity and was considered a potential source for control strategies to reduce FHB...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29228975/prediabetes-and-cardiovascular-complications-study-paccs-international-collaboration-4%C3%A2-years-summary-and-future-direction
#4
E U Nwose, R S Richards, P T Bwititi, E O Igumbor, E J Oshionwu, K Okolie, I C Onyia, A Pokhrel, P Gyawali, J N Okuzor, V M Oguoma, F W Gardiner, L Wang
OBJECTIVE: The prediabetes and cardiovascular complications studies proposes to develop a screening protocol for diabetes cardiovascular risk, and strategies for holistic management amongst others. Over 500 participants were recruited in the first 2 years of rural community research screening. Specific for this report, various published findings were reviewed. The objective is to summarize research outcomes and itemize limitations as they constitute basis of future directions. RESULTS: Affordability and availability are major confounding behavioural change wheel factors in the rural community...
December 11, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29227200/telepsychiatry-for-children-and-adolescents-a-review-of-the-prometted-project
#5
Catherine M Doyen, Marie-Joëlle Oreve, Eric Desailly, Virginie Goupil, Kevin Zarca, Yann L'Hermitte, Pauline Chaste, Marie-Ode Bau, Didier Beaujard, Sliman Haddadi, Ana Bibay, Yves Contejean, Marie-Thérèse Coutrot, Liora Crespin, Isabelle Frioux, Mario Speranza, Nolwenn Francois, Kelley Kaye
BACKGROUND: Telemedicine for children and adolescents is a public health topic, and since 2009 in France, the legal framework defines practical modalities. Some children with Attention Deficit with or without Hyperactivity Disorder, social anxiety, or Autism Spectrum Disorder (ASD) can be easily engaged within a teleconsultation model. Literature suggests new opportunities to facilitate the care process for the ASD person and his family: diagnosis with the use of validated instruments and parental accompaniment...
December 11, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29225744/a-comparison-between-ketorolac-and-nefopam-as-adjuvant-analgesics-for-postoperative-patient-controlled-analgesia-a-randomized-double-blind-prospective-study
#6
Ji-Seon Son, Aram Doo, Young-Jun Kwon, Young-Jin Han, Seonghoon Ko
Background: We compared the analgesic efficacy and side effects of ketorolac and nefopam that were co-administered with fentanyl via intravenous patient-controlled analgesia. Methods: One hundred and sixty patients scheduled for laparoscopic cholecystectomy were randomly assigned to ketorolac (Group K) or nefopam (Group N) groups. The anesthetic regimen was standardized for all patients. The analgesic solution contained fentanyl 600 µg and ketorolac 180 mg in Group K, and fentanyl 600 µg and nefopam 120 mg in Group N...
December 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29225415/a-co-flow-structure-for-goal-directed-internal-change
#7
Pascal Gambardella, Deborah E Polk, David Lounsbury, Ralph Levine
We describe a co-flow structure that models internal, goal-directed changes to an attribute (e.g., employee loyalty) of fundamental material (e.g., employees). This co-flow accommodates problems not adequately modeled with an existing, generic structure. Our structure builds on the co-flow proposed by Hines, which uses an information delay to model external change to an attribute. We use a first-order information delay to model both external changes to the attribute from the material stock and internal changes from an internal goal for the attribute...
January 2017: System Dynamics Review
https://www.readbyqxmd.com/read/29225412/identity-victimization-and-support-facebook-experiences-and-mental-health-among-lgbtq-youth
#8
Elizabeth A McConnell, Antonia Clifford, Aaron K Korpak, Gregory Phillips, Michelle Birkett
The rise of social networking sites (SNSs) has created new contexts within which lesbian, gay, bisexual, transgender, and queer (LGBTQ) youth and young adults manage their social identities and relationships. On one hand, SNSs provide important social support; on the other, they comprise another realm for victimization and discrimination. Context collapse refers to the ways diverse subgroups (e.g., family, co-workers) are often united in Facebook networks, which presents unique challenges related to outness...
November 2017: Computers in Human Behavior
https://www.readbyqxmd.com/read/29224346/speciation-of-mercury-in-selected-areas-of-the-petroleum-value-chain
#9
Astrid Avellan, John Stegemeier, Ke Gai, James G Dale, Heileen Hsu-Kim, Clément Levard, Dennis O'Rear, Thomas P Hoelen, Gregory V Lowry
Petroleum, natural gas, and natural gas condensate can contain low levels of mercury (Hg). The speciation of Hg can affect its behavior during processing, transport, and storage so efficient and safe management of Hg requires an understanding of its chemical form in oil, gas and byproducts. Here, X-ray absorption spectroscopy was used to determine the Hg speciation in samples of solid residues collected throughout the petroleum value chain including stabilized crude oil residues, sediments from separation tanks and condensate glycol dehydrators, distillation column pipe scale, and biosludge from wastewater treatment...
December 11, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29224205/healthcare-acquired-infections-prevention-strategies
#10
Shelanah A Fernando, Timothy J Gray, Thomas Gottlieb
Healthcare-acquired infections (HAI) impact on patient care and have cost implications for the Australian healthcare system. The management of HAI is exacerbated by rising rates of antimicrobial resistance (AMR). Health-care workers and a contaminated hospital environment are increasingly implicated in the transmission and persistence of multi-resistant organisms (MRO), as well as other pathogens, such as Clostridium difficile. This has resulted in a timely focus on a range of HAI prevention actions. Core components include antimicrobial stewardship, to reduce overuse and ensure evidence-based antimicrobial use; infection prevention strategies, to control MRO - particularly methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus spp...
December 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29221645/primary-care-led-weight-management-for-remission-of-type-2-diabetes-direct-an-open-label-cluster-randomised-trial
#11
Michael Ej Lean, Wilma S Leslie, Alison C Barnes, Naomi Brosnahan, George Thom, Louise McCombie, Carl Peters, Sviatlana Zhyzhneuskaya, Ahmad Al-Mrabeh, Kieren G Hollingsworth, Angela M Rodrigues, Lucia Rehackova, Ashley J Adamson, Falko F Sniehotta, John C Mathers, Hazel M Ross, Yvonne McIlvenna, Renae Stefanetti, Michael Trenell, Paul Welsh, Sharon Kean, Ian Ford, Alex McConnachie, Naveed Sattar, Roy Taylor
BACKGROUND: Type 2 diabetes is a chronic disorder that requires lifelong treatment. We aimed to assess whether intensive weight management within routine primary care would achieve remission of type 2 diabetes. METHODS: We did this open-label, cluster-randomised trial (DiRECT) at 49 primary care practices in Scotland and the Tyneside region of England. Practices were randomly assigned (1:1), via a computer-generated list, to provide either a weight management programme (intervention) or best-practice care by guidelines (control), with stratification for study site (Tyneside or Scotland) and practice list size (>5700 or ≤5700)...
December 4, 2017: Lancet
https://www.readbyqxmd.com/read/29221465/yale-school-of-public-health-symposium-on-lifetime-exposures-and-human-health-the-exposome-summary-and-future-reflections
#12
REVIEW
Caroline H Johnson, Toby J Athersuch, Gwen W Collman, Suraj Dhungana, David F Grant, Dean P Jones, Chirag J Patel, Vasilis Vasiliou
The exposome is defined as "the totality of environmental exposures encountered from birth to death" and was developed to address the need for comprehensive environmental exposure assessment to better understand disease etiology. Due to the complexity of the exposome, significant efforts have been made to develop technologies for longitudinal, internal and external exposure monitoring, and bioinformatics to integrate and analyze datasets generated. Our objectives were to bring together leaders in the field of exposomics, at a recent Symposium on "Lifetime Exposures and Human Health: The Exposome," held at Yale School of Public Health...
December 8, 2017: Human Genomics
https://www.readbyqxmd.com/read/29221328/uncontrolled-and-under-diagnosed-asthma-in-a-damascus-shelter-during-the-syrian-crisis
#13
Yousser Mohammad, Shaaban Rafea, Youssef Latifeh, Ali Khaddam, Bisher Sawaf, Mhd Ismael Zakaria, Mohammad Sadek Al Masalmeh, Yaser Fawaz, Abdoulraouf Allaham, Imad Almani, Hiba El-Tarcheh, Ayham Ghazal, Ali Zaher, Hala Rifai, Hamed Joumah, S Dresden Glockler-Lauf, Teresa To
Background: Studies have shown that poor shelter or dwelling conditions may lead to deteriorations in health. Those with asthma may be more susceptible to compromised living conditions and stress leading to a higher risk of asthma exacerbations. To describe the asthma control and quality of life of individuals with diagnosed asthma living in a shelter in Damascus, Syria and estimate the prevalence of respiratory symptoms in shelter dwellers without diagnosed asthma. Methods: In this cross-sectional study, all individuals 5 years and older living in Al-Herjalleh shelter with diagnosed asthma were recruited to complete a questionnaire, which included items related to their respiratory symptoms, asthma exacerbations, exposure to asthma triggers, medication use, and health-related quality of life before and since entering the shelter...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29220679/interaction-between-pre-treatment-drug-use-and-heterogeneity-of-psychiatric-diagnosis-predicts-outcomes-in-outpatients-with-co-occurring-disorders
#14
Oladunni Oluwoye, Katherine Hirchak, Emily Leickly, Jordan Skalisky, Sterling McPherson, Debra Srebnik, John M Roll, Richard K Ries, Michael G McDonell
We examined whether the interaction of baseline stimulant use, assessed by urine drug tests, and type of serious mental illness (SMI) diagnosis predicted stimulant use in a trial of contingency management (CM). The interaction between baseline stimulant use and SMI diagnoses was significant in the overall sample (p=0.002) when controlling for the main effects of treatment condition, baseline stimulant use, and SMI diagnosis. Similar results were also found within the CM sample. Individuals with bipolar disorder were more or less likely, depending on their baseline stimulant-drug test results, to use stimulants during treatment compared to those with other SMI diagnoses...
November 29, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29220606/why-walk%C3%A2-fly-managing-anger-grief-and-ptsd-2016-by-frances-helusky-221-pp-soft-cover-isbn-9780966263114-paragon-counseling-inc-co-published-with-virtualbookworm-com-publishing-college-station-tx-price-17-95
#15
https://www.readbyqxmd.com/read/29219214/whole-exome-sequencing-identifies-a-germline-met-mutation-in-two-siblings-with-hereditary-wild-type-ret-medullary-thyroid-cancer
#16
Marialuisa Sponziello, Silvia Benvenuti, Alessandra Gentile, Valeria Pecce, Francesca Rosignolo, Anna Rita Virzì, Melissa Milan, Paolo M Comoglio, Eric Londin, Paolo Fortina, Agnese Barnabei, Marialuisa Appetecchia, Ferdinando Marandino, Diego Russo, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti
Whole exome sequencing (WES) was used to investigate two Italian siblings with wild-type RET genotype, who developed medullary thyroid cancers (MTCs) and, later, primary prostate and breast cancers, respectively. The proband's MTC harbored a p.Met918Thr RET mutation; his sister's MTC was RET/RAS-wild-type. Both siblings had a germline mutation (p.Arg417Gln) in the extracellular Sema domain of the proto-oncogene MET. Experiments involving ectopic expression of MET p.Arg417Gln in MET-negative T47D breast cancer cells documented the mutant receptor's functionality and its ability to enhance cell migration and invasion...
December 8, 2017: Human Mutation
https://www.readbyqxmd.com/read/29219082/task-shifting-in-the-management-of-hypertension-in-kinshasa-democratic-republic-of-congo-a-cross-sectional-study
#17
Aimée M Lulebo, Didine K Kaba, Silvestre E-H Atake, Mala A Mapatano, Eric M Mafuta, Julien M Mampunza, Yves Coppieters
BACKGROUND: The Democratic Republic of the Congo (DRC) is characterized by a high prevalence of hypertension (HTN) and a high proportion of uncontrolled HTN, which is indicative of poor HTN management. Effective management of HTN in the African region is challenging due to limited resources, particularly human resources for health. To address the shortage of health workers, the World Health Organization (WHO) recommends task shifting for better disease management and treatment. Although task shifting from doctors to nurses is being implemented in the DRC, there are no studies, to the best of our knowledge, that document the association between task shifting and HTN control...
December 4, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29218681/management-strategies-to-facilitate-optimal-outcomes-for-patients-treated-with-delayed-release-dimethyl-fumarate
#18
Lori Mayer, Mary Kay Fink, Carrie Sammarco, Lisa Laing
Delayed-release dimethyl fumarate is an oral disease-modifying therapy that has demonstrated significant efficacy in adults with relapsing-remitting multiple sclerosis. Incidences of flushing and gastrointestinal adverse events are common in the first month after delayed-release dimethyl fumarate initiation. Our objective was to propose mitigation strategies for adverse events related to initiation of delayed-release dimethyl fumarate in the treatment of patients with multiple sclerosis. Studies of individually developed mitigation strategies and chart reviews were evaluated...
December 7, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29218432/the-2016-revision-of-the-who-classification-of-central-nervous-system-tumours-retrospective-application-to-a-cohort-of-diffuse-gliomas
#19
Te Whiti Rogers, Gurvinder Toor, Katharine Drummond, Craig Love, Kathryn Field, Rebecca Asher, Alpha Tsui, Michael Buckland, Michael Gonzales
The classification of central nervous system tumours has more recently been shaped by a focus on molecular pathology rather than histopathology. We re-classified 82 glial tumours according to the molecular-genetic criteria of the 2016 revision of the World Health Organization (WHO) Classification of Tumours of the Central Nervous System. Initial diagnoses and grading were based on the morphological criteria of the 2007 WHO scheme. Because of the impression of an oligodendroglial component on initial histological assessment, each tumour was tested for co-deletion of chromosomes 1p and 19q and mutations of isocitrate dehydrogenase (IDH-1 and 2) genes...
December 7, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29217952/control-of-hypertension-among-diabetic-patients-in-a-referral-hospital-in-tanzania-a-cross-sectional-study
#20
Semvua B Kilonzo, Daniel W Gunda, Fatma A Bakshi, Fredrick Kalokola, Henry A Mayala, Hollo Dadi
Background: Hypertension is common among diabetic patients. The co-existence of two conditions carries an excessive risk of severe complications and mortalities. Limited information exists on the determinants of poor hypertension control among these patients. We aimed at determining the prevalence and factors associated with poor hypertension control in these patients. Methods: Data of diabetic patients who were also hypertensive attending an outpatient clinic from 1 August 2015 to 31 December 2015 at Bugando Medical Centre were retrospectively analyzed...
September 2017: Ethiopian Journal of Health Sciences
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