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https://www.readbyqxmd.com/read/29243200/the-cascading-effects-of-multiple-dimensions-of%C3%A2-implementation-on-program-outcomes-a-test-of-a-theoretical-model
#1
Cady Berkel, Anne M Mauricio, Irwin N Sandler, Sharlene A Wolchik, Carlos G Gallo, C Hendricks Brown
This study tests a theoretical cascade model in which multiple dimensions of facilitator delivery predict indicators of participant responsiveness, which in turn lead to improvements in targeted program outcomes. An effectiveness trial of the 10-session New Beginnings Program for divorcing families was implemented in partnership with four county-level family courts. This study included 366 families assigned to the intervention condition who attended at least one session. Independent observers provided ratings of program delivery (i...
December 14, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29239272/mental-models-of-cause-and-inheritance-for-type-2-diabetes-among-unaffected-individuals-who-have-a-positive-family-history
#2
Sandra Daack-Hirsch, Lisa L Shah, Alyssa D Cady
Using the familial risk perception (FRP) model as a framework, we elicited causal and inheritance explanations for type 2 diabetes (T2D) from people who do not have T2D but have a family history for it. We identified four composite mental models for cause of T2D: (a) purely genetic; (b) purely behavioral/environmental; (c) direct multifactorial, in which risk factors interact and over time directly lead to T2D; and (d) indirect multifactorial, in which risk factors interact and over time cause a precursor health condition (such as obesity or metabolic syndrome) that leads to T2D...
December 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/29235387/work-life-integration-in-neuropsychology-a-review-of-the-existing-literature-and-preliminary-recommendations
#3
Maia Feigon, Cady Block, Leslie Guidotti Breting, Laura Boxley, Erica Dawson, Derin Cobia
OBJECTIVE: The purpose of the current review paper is to identify and describe challenges to work-life integration in neuropsychology, and from this review extrapolate an initial set of recommendations and present a set of scenarios in which the recommendations might apply in the hopes of improving quality of life for current and prospective neuropsychologists. Specific areas of focus include diversity, early and mid-career transitions, and potential barriers to advancement in specific practice settings...
December 13, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29164649/impact-of-alcohol-and-cigarette-smoking-consumption-in-male-fertility-potential-looks-at-lipid-peroxidation-enzymatic-antioxidant-activities-and-sperm-dna-damage
#4
S Aboulmaouahib, A Madkour, I Kaarouch, O Sefrioui, B Saadani, H Copin, M Benkhalifa, N Louanjli, R Cadi
Alcohol intake and cigarette smoking are the major lifestyle factors with negative impact on fertility. We were interested to evaluate the negative impact of these factors on oxidative stress (OS), enzymatic antioxidant activity (EAO) of spermatozoa and on its DNA damage. This study included 108 male infertile patients with normal range of sperm conventional parameters but with unexplained infertility in assisted reproductive technologies programme. Firstly, OS was analysed based on lipid peroxidation (MDA) and EAO which included catalase (CAT), superoxide dismutase (SOD) and glutathione reductase (GR)...
November 21, 2017: Andrologia
https://www.readbyqxmd.com/read/29046123/differential-effects-of-silver-nanoparticles-on-dna-damage-and-dna-repair-gene-expression-in-ogg1-deficient-and-wild-type-mice
#5
Sameera Nallanthighal, Cadia Chan, Thomas M Murray, Aaron P Mosier, Nathaniel C Cady, Ramune Reliene
Due to extensive use in consumer goods, it is important to understand the genotoxicity of silver nanoparticles (AgNPs) and identify susceptible populations. 8-Oxoguanine DNA glycosylase 1 (OGG1) excises 8-oxo-7,8-dihydro-2-deoxyguanine (8-oxoG), a pro-mutagenic lesion induced by oxidative stress. To understand whether defects in OGG1 is a possible genetic factor increasing an individual's susceptibly to AgNPs, we determined DNA damage, genome rearrangements, and expression of DNA repair genes in Ogg1-deficient and wild type mice exposed orally to 4 mg/kg of citrate-coated AgNPs over a period of 7 d...
October 19, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/29027196/care-mapping-for-the-medically-complex-child
#6
Rhonda G Cady
No abstract text is available yet for this article.
December 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28989973/cloning-assembly-and-modification-of-the-primary-human-cytomegalovirus-isolate-toledo-by-yeast-based-transformation-associated-recombination
#7
Sanjay Vashee, Timothy B Stockwell, Nina Alperovich, Evgeniya A Denisova, Daniel G Gibson, Kyle C Cady, Kristofer Miller, Krishna Kannan, Daniel Malouli, Lindsey B Crawford, Alexander A Voorhies, Eric Bruening, Patrizia Caposio, Klaus Früh
Genetic engineering of cytomegalovirus (CMV) currently relies on generating a bacterial artificial chromosome (BAC) by introducing a bacterial origin of replication into the viral genome using in vivo recombination in virally infected tissue culture cells. However, this process is inefficient, results in adaptive mutations, and involves deletion of viral genes to avoid oversized genomes when inserting the BAC cassette. Moreover, BAC technology does not permit the simultaneous manipulation of multiple genome loci and cannot be used to construct synthetic genomes...
September 2017: MSphere
https://www.readbyqxmd.com/read/28979928/a-conversation-with-sherry-cady
#8
Deirdre Lockwood
No abstract text is available yet for this article.
September 27, 2017: ACS Central Science
https://www.readbyqxmd.com/read/28952452/targeting-neuroinflammation-a-potential-for-anti-aging-interventions
#9
Gillian Cady, Marianna Sadagurski
No abstract text is available yet for this article.
September 22, 2017: Aging
https://www.readbyqxmd.com/read/28939579/help-seeking-behaviours-opportunistic-treatment-and-psychological-implications-of-adolescent-acne-cross-sectional-studies-in-schools-and-hospital-outpatient-departments-in-the-uk
#10
Karishma Parimal Desai, Claire Martyn-Simmons, Russell Viner, Terry Segal
BACKGROUND: Acne vulgaris (acne) is a common adolescent skin condition. It is associated with negative psychological impacts and sufferers do not easily seek help, hence is undertreated. OBJECTIVES: We investigated the self-reported prevalence, severity and psychological sequelae of acne, together with assessing help-seeking behaviour and its barriers, in separate school and hospital samples. We explored opportunistic treatment by paediatricians. METHODS: Self-reported survey with participants drawn from: (1) 120 adolescents aged 13-18 in a London tertiary paediatric outpatient department and (2) 482 adolescents from two London schools, aged 11-18...
September 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28915237/dna-replication-stress-restricts-ribosomal-dna-copy-number
#11
Devika Salim, William D Bradford, Amy Freeland, Gillian Cady, Jianmin Wang, Steven C Pruitt, Jennifer L Gerton
Ribosomal RNAs (rRNAs) in budding yeast are encoded by ~100-200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA) locus. Copy number of rDNA repeat units in eukaryotic cells is maintained far in excess of the requirement for ribosome biogenesis. Despite the importance of the repeats for both ribosomal and non-ribosomal functions, it is currently not known how "normal" copy number is determined or maintained. To identify essential genes involved in the maintenance of rDNA copy number, we developed a droplet digital PCR based assay to measure rDNA copy number in yeast and used it to screen a yeast conditional temperature-sensitive mutant collection of essential genes...
September 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28913663/effects-of-a-program-to-promote-high-quality-parenting-by-divorced-and-separated-fathers
#12
Irwin Sandler, Heather Gunn, Gina Mazza, Jenn-Yun Tein, Sharlene Wolchik, Cady Berkel, Sarah Jones, Michele Porter
This paper reports on the effects on parenting and on children's mental health problems and competencies from a randomized trial of a parenting program for divorced and separated fathers. The program, New Beginnings Program-Dads (NBP-Dads), includes ten group sessions (plus two phone sessions) which promote parenting skills to increase positive interactions with children, improve father-child communication, use of effective discipline strategies, and skills to protect children from exposure to interparental conflict...
September 15, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28894789/impact-of-the-mk-vi-skinsuit-on-skin-microbiota-of-terrestrial-volunteers-and-an-international-space-station-bound-astronaut
#13
Richard A Stabler, Helena Rosado, Ronan Doyle, David Negus, Philip A Carvil, Juan G Kristjánsson, David A Green, Rafael Franco-Cendejas, Cadi Davies, Andreas Mogensen, Jonathan Scott, Peter W Taylor
Microgravity induces physiological deconditioning due to the absence of gravity loading, resulting in bone mineral density loss, atrophy of lower limb skeletal and postural muscles, and lengthening of the spine. SkinSuit is a lightweight compression suit designed to provide head-to-foot (axial) loading to counteract spinal elongation during spaceflight. As synthetic garments may impact negatively on the skin microbiome, we used 16S ribosomal RNA (rRNA) gene amplicon procedures to define bacterial skin communities at sebaceous and moist body sites of five healthy male volunteers undergoing SkinSuit evaluation...
2017: NPJ Microgravity
https://www.readbyqxmd.com/read/28831799/preparation-of-some-homologous-tempo-nitroxides-and-oxoammonium-salts-notes-on-the-nmr-spectroscopy-of-nitroxide-free-radicals-observed-radical-nature-of-oxoammonium-salt-solutions-containing-trace-amounts-of-corresponding-nitroxides-in-an-equilibrium-relationship
#14
James M Bobbitt, Nicholas A Eddy, Clyde X Cady, Jing Jin, Jose A Gascon, Svetlana Gelpí-Dominguez, Jerzy Zakrzewski, Martha D Morton
Three new homologous TEMPO oxoammonium salts and three homologous nitroxide radicals have been prepared and characterized. The oxidation properties of the salts have been explored. The direct (13)C NMR and EPR spectra of the nitroxide free radicals and the oxoammonium salts, along with TEMPO and its oxoammonium salt, have been successfully measured with little peak broadening of the NMR signals. In the spectra of all ten compounds (nitroxides and corresponding oxoammonium salts), the carbons in the 2,2,6,6-tetramethylpiperidine core do not appear, implying paramagnetic properties...
September 6, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28803414/laparoscopic-reversal-of-mini-gastric-bypass-to-original-anatomy-for-severe-postoperative-malnutrition
#15
Laurent Genser, Antoine Soprani, Malek Tabbara, Jean-Michel Siksik, Jean Cady, Sergio Carandina
PURPOSE: Malnutrition after mini-gastric bypass (MGB) is a rare and dreaded complication with few data available regarding its surgical management. We aim to report the feasibility, safety, and results of laparoscopic reversal of MGB to normal anatomy (RMGB) in case of severe and refractory malnutrition syndrome after intensive nutritional support (SRMS). METHODS: A 10-year retrospective chart review was performed on patients who underwent RMGB (video included) for SRMS following MGB...
August 12, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28738988/use-of-cascading-a3s-to-drive-systemwide-improvement
#16
Laura E Winner, Timothy J Burroughs, Julie A Cady-Reh, Richard Hill, Robert E Hody, Richard L Powers, Tiffany Callender, Renee Demski, Peter J Pronovost
No abstract text is available yet for this article.
August 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28726791/implementation-of-a-multidisciplinary-guideline-improves-preterm-infant-admission-temperatures
#17
M W Harer, B Vergales, T Cady, A Early, C Chisholm, J R Swanson
BACKGROUND: Hypothermia is a common problem in preterm infants immediately following delivery.Local problem:The rate of admission hypothermia in our neonatal intensive care unit (NICU) was above the rate of comparable NICUs in the Vermont Oxford Network. METHODS: To reduce the rate of preterm admission hypothermia, a quality improvement (QI) project was implemented, utilizing the plan-do-study-act (PDSA) methodology. A guideline for delivery room thermoregulation management in <35-week infants at the University of Virginia was created and put into practice by a multidisciplinary team...
November 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28720691/disseminated-cryptococcosis-in-an-immunocompetent-patient
#18
Pradeep Mada, Brad Nowack, Beth Cady, Andrew Stevenson Joel Chandranesan
Cryptococcosis is a fungal infection which is commonly associated with immune-compromised state. Disseminated infection in immunocompetent individuals is extremely rare. We present a case of a 56-year-old African American patient who presented with unilateral knee pain and swelling and was subsequently diagnosed with cryptococcal bone mass with dissemination of infection.
July 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28711280/unsupervised-extraction-of-stable-expression-signatures-from-public-compendia-with-an-ensemble-of-neural-networks
#19
Jie Tan, Georgia Doing, Kimberley A Lewis, Courtney E Price, Kathleen M Chen, Kyle C Cady, Barret Perchuk, Michael T Laub, Deborah A Hogan, Casey S Greene
Cross-experiment comparisons in public data compendia are challenged by unmatched conditions and technical noise. The ADAGE method, which performs unsupervised integration with denoising autoencoder neural networks, can identify biological patterns, but because ADAGE models, like many neural networks, are over-parameterized, different ADAGE models perform equally well. To enhance model robustness and better build signatures consistent with biological pathways, we developed an ensemble ADAGE (eADAGE) that integrated stable signatures across models...
July 26, 2017: Cell Systems
https://www.readbyqxmd.com/read/28612541/-reliability-and-validity-of-a-simplified-version-of-acne-specific-quality-of-life-assessment-instrument-in-han-populations-in-sichuan
#20
Dan Du, Xiao-Xue Li, Yu Pan, Ting Yang, Dan Hao, Xian Jiang
OBJECTIVES: To assess the reliability and validity of a simplified version of acne-specific quality of life (Acne-Qol-19) instrument in Han populations in Sichuan province. METHODS: Acne-Qol-19 was administered to 264 acne patients. Internal consistency, split-half reliability, content validity, criterion validity and construct validity (factor analysis) of Acne-Qol-19 were assessed. RESULTS: The Acne-Qol-19 obtained a Cronbach's α of 0.953 and split-half reliability of 0...
March 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
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