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Jiuming Wan, Shaopeng Wu, Yue Xiao, Quantao Liu, Erik Schlangen
Ceramic fiber, with a major composition of Al₂O₃ and SiO₂, has advantages of stability at relatively high temperature, big specific surface area and resistance to external mechanical vibration. It has the potential contribution of improving the rutting resistance and temperature sensitivity of modified asphalt binder by proper modification design. In this research, ceramic fiber was introduced into both pen 60/80 and pen 80/100 asphalt binder by different weight ratios. An asphalt penetration test, softening point test, ductility test and dynamic viscoelastic behavior were conducted to characterize and predict the ceramic fiber modified asphalt mortar (CFAM)...
September 21, 2016: Materials
Maureen Leahey, Lorraine M Wright
Much has been written about the global implementation of the Calgary Family Assessment and Intervention Models (CFAM/CFIM) and the application of these practice models in various clinical settings. The purpose of this article is to provide a brief update on the background of CFAM/CFIM, and the current applications of the models as evidenced in the English-language literature. Little has been written about the use of CFAM/CFIM in a personal context, however. As originators of the models, we offer our own narratives and reflections about the reciprocity between the personal and professional applications of our models and the ways that our personal experiences have extended our understanding about the utility of the models for clinical practice with families...
November 2016: Journal of Family Nursing
Amélie Desmarais, Estelle Pujos-Guillot, Bernard Lyan, Jean-François Martin, Nadine Leblanc, Paul Angers, Jean-Louis Sébédio
Cyclic fatty acid monomers (CFAM) are mainly formed during heat treatments, such as frying, of edible oils. These fatty acids are mixtures of disubstituted five- or six-carbon-membered ring structures. Some earlier studies have suggested that some of these molecules could be metabolized and detoxified, but so far, neither the detoxification mechanisms nor the metabolite identifications have been elucidated. The objective of the present study was to identify the metabolites resulting from the metabolism and detoxification of CFAM...
April 2015: Lipids
Cheng Zhang, Lin Tao, Chu Qin, Peng Zhang, Shangying Chen, Xian Zeng, Feng Xu, Zhe Chen, Sheng Yong Yang, Yu Zong Chen
Similarity-based clustering and classification of compounds enable the search of drug leads and the structural and chemogenomic studies for facilitating chemical, biomedical, agricultural, material and other industrial applications. A database that organizes compounds into similarity-based as well as scaffold-based and property-based families is useful for facilitating these tasks. CFam Chemical Family database was developed to hierarchically cluster drugs, bioactive molecules, human metabolites, natural products, patented agents and other molecules into functional families, superfamilies and classes of structurally similar compounds based on the literature-reported high, intermediate and remote similarity measures...
January 2015: Nucleic Acids Research
Marianne Kläusler-Troxler, Elisabeth Kurth, Rebecca Spirig
BACKGROUND: Routine postnatal care normally addresses only the mother and her child. In Switzerland, counselling for all parents and their children is provided by family nurses in a community-based health care setting. We implemented a new approach to ensure father involvement within the framework of the Calgary Family Assessment (CFAM) and the Calgary Intervention Model CFIM of Wright and Leahey (2013) in the northwest of Switzerland. AIM: This qualitative study explored how mothers and fathers experienced the newly developed family-centred consultation...
August 2014: Pflege
Mariana Cristina Lobato dos Santos Ribeiro Silva, Nancy Jean Moules, Lucía Silva, Regina Szylit Bousso
The 15-minute family interview is a condensed form of the Calgary Family Assessment and Intervention Models (CFAM and CFIM) that aims to contribute to the establishment of a therapeutic relationship between nurses and family and to implement interventions to promote health and suffering relief, even during brief interactions. This study investigated the experience of nurses from the Family Health Strategy (FHS) who used the 15-minute interview on postpartum home. The qualitative research was conducted in three stages: participants' training program, utilization of the 15-minute family interview by participants, and interviews with nurses...
June 2013: Revista da Escola de Enfermagem da U S P
Olivier Berdeaux, Stéphane Gregoire, Cindie Fournier, William W Christie, Pierre Lambelet, Jean-Louis Sébédio
The purpose of this work was to identify an unknown component which has been detected during the analysis of cyclic fatty acid monomers (CFAMs) in low erucic acid rapeseed oils (LEAR). A sample of crude LEAR was transformed into fatty acid methyl esters (FAMEs) and hydrogenated using PtO(2). The hydrogenated sample was fractionated by reversed-phase high-performance liquid chromatography (RP-HPLC) and the fraction containing the CFAMs transformed into picolinyl esters. Analysing these picolinyl derivatives by gas-liquid chromatography coupled to mass spectrometry (GC-MS) showed that the unknown product observed in LEAR is the 11,12-methylene-octadecanoic acid...
September 2010: Chemistry and Physics of Lipids
Angel Chu Kee Lee, Shing On Leung, Polly Siu Lingchan, Joyce Oi Kwan Chung
Because the structure, development, and functioning of a family plays an important role in health and illness, preparing nursing students to assess families in health care settings is of critical importance. A quasi-experimental design using a pre- and postcourse questionnaire was used to examine students' perceived knowledge about family assessment and perceived difficulty applying family assessment in the clinical setting. The Calgary Family Assessment Model (CFAM) was taught in an elective nursing course, "Families in Health and Illness," offered at the University of Hong Kong...
May 2010: Journal of Family Nursing
Olivier Berdeaux, Véronique Fournier, Pierre Lambelet, Fabiola Dionisi, Jean Louis Sébédio, Frédéric Destaillats
Long-chain polyunsaturated fatty acids (LC-PUFAs) present in fish oils are thermolabile molecules. Among the degradation reactions encountered, thermal cyclization occurs during refining or other heat treatments. Numerous studies have been carried out in the past to quantify and determine the structures of cyclic fatty acid monomers (CFAMs) formed from oleic, linoleic and linolenic acids in heated vegetable oils. Recently, much attention have been given to LC-PUFAs due to their potential health benefits. However, data on quantification of CFAMs formed from these fatty acids, such as eicosapentaenoic acid (EPA, cis-5, cis-8, cis-11, cis-14, cis-17 20:5) and docosahexaenoic acid (DHA, cis-4, cis-7, cis-10, cis-13, cis-16, cis-19 22:6), the two main LC-PUFAs in fish oils, are scarce...
January 5, 2007: Journal of Chromatography. A
A Romero, S Bastida, F J Sánchez-Muniz
During the frying process, oxidation, hydrolysis, polymerization, isomerization, and cyclization occur. Polymers and Cyclic fatty acid monomers (CFAM) are potentially toxic, and the latter are detected at relatively low levels (0.01-0.7%) in used frying oils. Twenty fryings of different frozen foods were carried out over 10 consecutive days in sunflower oil (SO) and in high oleic acid sunflower oil (HOSO). Fatty acid methyl ester derivates were hydrogenated with platinum oxide catalyst under hydrogen. Ethyl palmitate was added as an internal standard before hydrogenation...
October 2006: Food and Chemical Toxicology
Florent Joffre, Alexandre Roy, Lionel Bretillon, Bruno Pasquis, Jean-Pierre Sergiel, Olivier Loreau, Jean-Michel Chardigny, Jean-Louis Sébédio
Cyclic fatty acid monomers (CFAM), which occur from the intramolecular cyclisation of linoleic and linolenic acids, are subsequently present in some edible oils and are suspected to induce metabolic disorders. One may suggest that the presence of a ring would alter the ability of the organism to oxidise these molecules. In order to test this hypothesis, we assessed the oxidative metabolism of CFAM in rats. For this purpose, rats were force-fed from 1.5 to 2.6 MBq of [1-(14)C]-linoleic acid, [1-(14)C]-linolenic acid, [1-(14)C]-CFAM-18:2 or [1-(14)C]-CFAM-18:3, and 14CO2 production was monitored for 24 h...
March 2004: Reproduction, Nutrition, Development
Lionel Bretillon, Stefan E H Alexson, Florent Joffre, Bruno Pasquis, Jean-Louis Sébédio
Cyclic FA monomers (CFAM) formed during heating of alpha-linolenic acid have been reported to interfere in hepatic metabolism in a putatively peroxisome proliferator-activated receptor alpha (PPARalpha)-dependent manner. In the present work, CFAM (0.5% of the diet) were administered for 3 wk to wild-type and PPARalpha-null mice of both genders to elucidate the role of PPARalpha in mediating the effects of CFAM on the activity of acyl-CoA oxidase (ACO) and omega-laurate hydroxylase (CYP4A), the regulation of which is known to be dependent on the PPARalpha...
September 2003: Lipids
F Joffre, J -C. Martin, M Genty, L Demaison, O Loreau, J -P. Noël, J -L. Sébédio
Cyclic fatty acid monomers (CFAM) occur from linoleic (CFAM-18:2) or linolenic (CFAM-18:3) acids present in some edible oils as a result of domestic frying or industrial refining. They present adverse effects in pups and weaning rats. In the present work, we studied the importance of hepatic oxidation in the metabolism of CFAM. For this purpose, kinetic parameters of Carnitine Palmitoyl Transferase I (key enzyme of the channeling of the fatty acids into the mitochondrial beta-oxidation pathway) and Acyl CoA Oxidase (key enzyme of the peroxisomal oxidation pathway) towards CFAM-18:2 and CFAM-18:3 were calculated on hepatic sub-cellular fractions of rats...
October 2001: Journal of Nutritional Biochemistry
I Leboeuf
The diagnosis of a malignant brain tumour can be devastating for both patients and their families. Despite neurological and cancer treatment advances, there has been little progress in extending life expectancy for these patients. Cassileth et al. (1985) suggest that of all types of cancer, brain tumours cause the most psychosocial repercussions for the family. The brain tumour clinical nurse specialist (CNS) is in a strategic position to intervene with families along the continuum of care by using a family-oriented approach which can facilitate their adaptation to this health problem...
September 2000: L' Axone
D Murdoch-Eaton, M Darowski, J Livingston
Neurological integrity in sick children is difficult to assess clinically. The aim of this study was to determine the predictive value of EEG activity recorded with a bedside EEG analysing monitor in an intensive care unit. EEG activity was monitored in 108 children (age range 2 weeks to 16 years, median 1.7 years) considered at risk for cerebral abnormalities with a cerebral function analysing monitor (CFAM). Recordings were evaluated for features of background EEG activity including mean amplitude, frequencies, and symmetry...
February 2001: Developmental Medicine and Child Neurology
A W Gavilanes, J S Vles, von Siebenthal K, J P Reulen, F H Nieman, van Sprundel R, C E Blanco
OBJECTIVES: To investigate the relationships between systemic and cerebral haemodynamics and oxygenation, and electroencephalogram (EEG) amplitude and frequency analysis studied by the cerebral function analyzing monitor (CFAM) during progressive hypovolemic hypotension. METHODS: Six piglets of 1 week of age, weighing 1.9-3.4 kg were mechanically ventilated under 1-1.5% halothane anaesthesia. After 1 h stabilization, blood was withdrawn in aliquots of 10 ml/kg over 15 min up to a total of 40-60 ml/kg...
January 2001: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
D Ménard, A Saucier
This article resulted from both authors sharing their professional experience; it illustrates an application of the Calgary Family Assessment Model (CFAM) and Calgary Family Intervention Model (CFIM) by Lorraine Wright and Maureen Leahey (1994). Indeed, some of the theoretical concepts presented by these authors were used to guide our analysis of the clinical situation. This brief intervention, consisting of four meetings, aimed to promote family coping during the palliative phase. Throughout each of the meetings, the nurse illustrates the principles guiding therapeutic conversations with the family, i...
2000: Canadian Oncology Nursing Journal, Revue Canadienne de Nursing Oncologique
H Keunen, J S Vles, J L Van Reempts, D Gavilanes, T H Hasaart
OBJECTIVE: To examine the effect of repetitive total umbilical cord occlusions on electrocortical brain activity as measured by cerebral function analyzing monitoring (CAFM) and the histologic outcome in immature sheep fetuses. STUDY DESIGN: We performed brief repeated total umbilical cord occlusions, two every 5 minutes, in 12 immature sheep fetuses (at 90 days of gestation, term 147 days) until fetal mean arterial pressure dropped below 50% of baseline value during two successive occlusions...
July 2000: Journal of the Society for Gynecologic Investigation
C Lamboni, J L Sébédio, E G Perkins
This study was conducted to investigate the effects of dietary cyclic fatty acid monomers (CFAM), contained in heated fat from a commercial deep-fat frying operation, on rat liver enzyme activity. A partially hydrogenated soybean oil (PHSBO) used 7 d (7-DH) for frying foodstuffs, or 0.15% methylated CFAM diets was fed to male weanling rats in comparison to a control group fed a nonheated PHSBO (NH) diet in a 10-wk experiment. All diets were isocaloric with 15% fat. Animals fed either CFAM or 7-DH diets showed increased hepatic content of cytochrome (cyt...
July 1998: Lipids
C E Thomsen, P Prior
Methodology for assessment of depth of anaesthesia based on analysis of the electroencephalogram (eeg) is controversial. Techniques range from display of single measures, for example median value of the frequency spectrum, to dedicated pattern recognition systems based on measures of several eeg features. We have compared the performance of four techniques using tape-recorded data from 23 patients anaesthetised with either halothane or isoflurane using standardised regimens. The techniques were: median frequency, spectral edge frequency, the cerebral function analysing monitor (CFAM-1) and a depth of anaesthesia monitor based on eeg pattern recognition (ADAM)...
February 23, 1998: Ugeskrift for Laeger
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