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https://www.readbyqxmd.com/read/28521083/inflammatory-infiltrate-and-mucosal-remodeling-in-chronic-rhinosinusitis-with-and-without-polyps-structured-histopathologic-analysis
#1
Hannah N Kuhar, Bobby A Tajudeen, Mahboobeh Mahdavinia, Paolo Gattuso, Ritu Ghai, Pete S Batra
BACKGROUND: Chronic rhinosinusitis (CRS) is commonly classified into CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Structured histopathologic reporting has the potential to identify salient histologic markers to differentiate subtypes and provide insights into pathophysiologic mechanisms in CRS. METHODS: A structured histopathology report of 13 variables was prospectively employed to analyze ethmoid sinus tissue removed during endoscopic sinus surgery for 99 patients, including 43 CRSsNP and 56 CRSwNP...
May 18, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28512370/occupational-contact-allergy-to-omeprazole-and-ranitidine
#2
Inmaculada Herrera-Mozo, Pere Sanz-Gallen, Gabriel Martí-Amengual
Omeprazole is a proton pump inhibition and ranitidine is an H2 histamine receptor antagonist widely used in the treatment of gastroesophageal reflex disease, peptic ulcer disease, Zollinger-Ellison syndrome and as a protector of the gastric mucosae. We report a case of occupational contact allergy to omeprazole and ranitidine. A 48-year-old man, with no pre-existing history of atopy or lifestyle factors. He neither had any medical history of consumption of drugs such as ranitidine and omeprazole. He worked for 19 months in the pharmaceutical company that manufactured ranitidine base...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28490883/retrospective-analysis-of-non-laboratory-based-adverse-drug-reactions-induced-by-intravenous-radiocontrast-agents-in-a-joint-commission-international-accredited-academic-medical-center-hospital-in-china
#3
Qin-Lan Chen, Xiao-Ying Zhao, Xiao-Mi Wang, Na Lv, Ling-Ling Zhu, Hui-Min Xu, Quan Zhou
The authors retrospectively analyzed the pattern and characteristics of non-laboratory-based adverse drug reactions (ADRs) induced by intravenous radiocontrast agents in a large-scale hospital in China during 2014-2015. There were 314 ADR cases among 118,208 patients receiving enhanced CT or MRI examinations. The frequency of moderate/severe ADRs defined by Chinese Society of Radiology (ie, severe vomiting, systematic urticaria, facial swelling, dyspnea, vasovagal reaction, laryngeal edema, seizure, trembling, convulsions, unconsciousness, shock, death, and other unexpected adverse reactions) was rare (0...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28487553/maternal-cytokine-status-may-prime-the-metabolic-profile-and-increase-risk-for-obesity-in-children
#4
B Englich, G Herberth, U Rolle-Kampczyk, S Trump, S Röder, M Borte, G I Stangl, M von Bergen, I Lehmann, K M Junge
BACKGROUNDThe maternal inflammation status during pregnancy has been associated to metabolic imprinting and obesity development in the child. However the influence of the maternal Th2 cytokines IL4, IL5 and IL13 has not been studied so far.METHODSWe investigated the relationship between maternal innate (IL6, IL8, IL10 and TNFα) and adaptive (IFNγ, IL4, IL5 and IL13) blood cytokine levels at 34 weeks of gestation and children's overweight development until the age of three years in 407 children of the German longitudinal LINA cohort...
May 10, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28484688/what-are-the-effects-of-a-mediterranean-diet-on-allergies-and-asthma-in-children
#5
REVIEW
Jose A Castro-Rodriguez, Luis Garcia-Marcos
This review updates the relationship between the adherence to Mediterranean diet (MedDiet) assessed by questionnaire and asthma, allergic rhinitis, or atopic eczema in childhood. It deals with the effect of MedDiet in children on asthma/wheeze, allergic rhinitis, and atopic dermatitis/eczema, and also with the effect of MedDiet consumption by the mother during pregnancy on the inception of asthma/wheeze and allergic diseases in the offspring. Adherence to MedDiet by children themselves seems to have a protective effect on asthma/wheezing symptoms after adjustment for confounders, although the effect is doubtful on lung function and bronchial hyperresponsiveness...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28480729/an-unusual-cause-of-boerhaave%C3%A2-s-syndrome-in-a-young-patient
#6
Samuel Fernandes, Carlos Noronha Ferreira, José Freire, José Velosa
An 18-year-old male patient with a history of atopy and intermittent dysphagia for solids, presented to the emergency department with sudden onset total dysphagia followed by hematemesis, after ingesting an ibuprofen tablet. Urgent upper gastrointestinal endoscopy revealed a deep laceration just above the tablet impacted in the distal esophagus. Abdominal CT-scan confirmed the suspicion of an esophageal perforation. The impacted tablet was broken up with biopsy forceps, and a covered metallic stent (Hanarostent® 60/100x20/26mm) was placed across the cardia effectively excluding the fistula...
May 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28465864/parental-snoring-and-environmental-pollutants-but-not-aeroallergen-sensitization-are-associated-with-childhood-snoring-in-a-birth-cohort
#7
Jennifer A Kannan, Cole Brokamp, David I Bernstein, Grace K LeMasters, Gurjit K Khurana Hershey, Manuel S Villareal, James E Lockey, Patrick H Ryan
The objective of this study was to determine whether atopy and other clinical and environmental variables predict the risk of childhood habitual snoring (HS) in a birth cohort born to atopic parents. Participants completed clinical evaluations and questionnaires at ages 1-4 and age 7. HS was defined as snoring ≥3 nights/week. Traffic-related air pollution (TRAP) exposure was estimated using land-use regression. The association between early (≤age 4) and current (age 7) allergic disease, environmental exposures, and snoring at age 7 was examined using adjusted logistic regression...
March 1, 2017: Pediatric Allergy, Immunology, and Pulmonology
https://www.readbyqxmd.com/read/28465037/is-there-any-difference-regarding-atopy-between-children-with-familial-mediterranean-fever-and-healthy-controls
#8
Ç Aydoğmuş, N A Ayaz, M Çakan, F Çipe, N Topal, Ö B Öner, G Keskindemirci, A Akçay
INTRODUCTION: There are only a few studies regarding the prevalence of atopy in Familial Mediterranean fever (FMF) patients, and their results are conflicting. METHODS: In this study children with the diagnosis of FMF were evaluated for the presence of atopy by comparing with controls. One hundred and eighteen children diagnosed as FMF and 50 healthy age and sex matched controls were enrolled. They were evaluated for the presence of rhinitis, atopic dermatitis, urticaria and asthma...
April 29, 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/28464036/prevalence-and-determinants-of-asthma-in-adults-in-kinshasa
#9
Kabengele Benoit Obel, Kayembe Jean Marie Ntumba, Kayembe Patrick Kalambayi, Akilimali Pierre Zalagile, Kaba Didine Kinkodi, Kashongwe Zacharie Munogolo
BACKGROUND: Epidemiological data on asthma among adults in sub-Saharan Africa are sparse. OBJECTIVE: To determine the prevalence of and factors associated with asthma among adults in Kinshasa. METHODS: A previously validated asthma questionnaire was administered to an adult population aged ≥18 years in urban and peri-urban suburbs of Kinshasa. A random stratified multi-stage sampling plan was used to select the study participants. Logistic regression was used to identify factors associated with asthma...
2017: PloS One
https://www.readbyqxmd.com/read/28454657/vitamin-d-and-atopy
#10
EDITORIAL
Theoharis C Theoharides
No abstract text is available yet for this article.
April 25, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28452100/pediatric-psoriasis-should-we-be-concerned-with-comorbidities-a-cross-sectional-study
#11
A Kelati, H Baybay, A Najdi, S Zinoune, F Z Mernissi
BACKGROUND: Similarly to psoriasis in adult, Recent research has linked psoriasis to several comorbidities in children. Our objective was to describe comorbidities associated with pediatric psoriasis, to investigate their relationship with psoriasis characteristics and severity, and to perform a review of the literature. METHODS: A cross-sectional study was performed on a sample of Moroccan psoriatic children, during two years 2014 -2016. RESULTS: 64 psoriatic children had metabolic comorbidities in association with psoriasis, 20 children had non-metabolic comorbidities and 76 children didn't have any comorbidities...
April 28, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28452068/an-evaluation-of-vitamin-d-levels-in-children-with-seasonal-allergic-rhinitis-during-pollen-season
#12
Şeyhan Kutluğ, Mehtap Kılıç, Birşen Bilgici, Şule Paksu, Alişan Yıldıran, Recep Sancak
BACKGROUND: Serum vitamin D levels have not been studied in children with seasonal allergic rhinitis (SAR). The aim of this study was to evaluate the vitamin D levels of children with SAR and to compare them to levels in healthy children during pollen season. METHODS: This study was conducted in 100 children with SAR and 100 healthy controls. Clinical and laboratory evaluations and vitamin D analyses of all the participants were performed between the months of April and July...
April 27, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28449974/in-hospital-acute-myocardial-infarction-a-case-of-type-ii-kounis-syndrome
#13
Rita Marinheiro, Pedro Amador, Filipa Semedo, Catarina Sá, Tatiana Duarte, Sara Gonçalves, Filipe Seixo, Rui Caria
Kounis syndrome (KS) is the coincidental occurrence of acute coronary syndrome (ACS) and anaphylactic or allergic insult. It results from mast cell degranulation with subsequent release of numerous inflammatory mediators, leading to coronary vasospasm or atheromatous plaque rupture. Diagnosis is clinical and based on the temporal relationship between the two events. Despite the growing number of reported cases, especially in southern Europe, the lack of awareness of this association may lead to under-reporting in Portugal...
April 24, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28449554/a-study-of-single-nucleotide-polymorphisms-of-tumour-necrosis-factor-%C3%AE-1031-and-tumour-necrosis-factor-%C3%AE-252-in-chronic-rhinosinusitis
#14
Khairunnisak Misron, Suzina Sheikh Ab Hamid, Azlina Ahmad, Ramiza Ramza Ramli
Objectives: This case-controlled study aimed to identify the association of tumor necrosis factor (TNF)α-1031 and TNFβ+252 gene polymorphisms between chronic rhinosinusitis (CRS) and healthy controls. Another purpose of this study was to investigate the associations of these gene polymorphisms with factors related to CRS. Methods: All deoxyribonucleic acid (DNA) samples were genotyped for TNFα-1031 and TNFβ+252 genes by mean of polymerase chain reaction (PCR) and restriction fragment length polymorphisms (RFLP)...
April 28, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28447153/-neurodermatitis-atopy-of-the-skin
#15
R Fölster-Holst
Atopic dermatitis is one of the most common skin diseases and is associated with an impaired quality of life due to tormenting itching and stigmatization. The disease almost always manifests in early childhood and exhibits specific features in this phase, with involvement of the extensor sides of the extremities. During the further course of disease, the typical flexor involvement becomes quite clear and a considerable proportion of patients develop the associated atopic respiratory diseases. Therapeutic and prophylactic measures focus on the prevention of trigger factors, basic skin care, and application of lipid-replenishing creams, as well as patient and parent education...
April 26, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28441988/asthma-pathogenesis-diagnosis-and-management-in-the-elderly
#16
M Asghar Pasha, Britta Sundquist, Robert Townley
BACKGROUND: Due to the aging population, there is an increase in the number of elderly patients with asthma. Although signs and symptoms are similar to those in younger patients, diagnosis can be challenging due to presence of coexisting conditions in this population. OBJECTIVES: The purpose of this review was to highlight the challenges with regards to diagnosis, management, the high rates of medical costs and mortality in elderly asthmatics. METHODS AND RESULTS: Scientific literature regarding asthma in the elderly population was reviewed...
May 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28441985/atopy-asthma-and-the-elderly-a-paradigm-for-personalized-therapy
#17
Joseph A Bellanti, Russell A Settipane
No abstract text is available yet for this article.
May 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28425254/wheezing-asthma-and-atopy-in-premature-infants-at-2-years-of-age
#18
Sevim Ünal, Ayşenur Kaya, Leyla Bilgin, Emine Misirlioğlu, Can Naci Kocabaş
BACKGROUND/AIM: We aimed to evaluate wheezing, bronchial asthma (BA), and atopy in premature infants at 2 years of age via a cross-sectional study. MATERIALS AND METHODS: Premature infants at <37 weeks of gestational age (GA) were assessed for atopy by skin-prick test and serum immunoglobulin E level at 2 years of age. The family's and infant's histories of allergy, BA, atopy, and wheezing were obtained by questionnaire and from hospital records. RESULTS: There were 98 infants, with mean birth weight (BW) 1517...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28425249/prediction-of-atopy-via-total-immunoglobulin-e-levels-andskin-prick-tests-in-patients-with-psoriasis
#19
Emine Sümeyye Ünal, Ülker Gül, Adile Berna Dursun, Ferda Öner Erkekol
BACKGROUND/AIM: Although the etiopathogeneses of psoriasis and atopy appear to be different, psoriasis has been found to be associated with atopy and atopic dermatitis. In this study, we aimed to determine the role of atopy by examining the medical history and clinical and laboratory findings of patients with psoriasis. MATERIALS AND METHODS: Patients with psoriasis, asthma patients, and healthy volunteers were included in the study. Serum total immunoglobulin E (IgE) levels were obtained, and prick tests were administered to all groups...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28421172/aspiration-risk-and-respiratory-complications-in-patients-with-esophageal-atresia
#20
REVIEW
Thomas Kovesi
Chronic, long-term respiratory morbidity (CRM) is common in patients with a history of repaired congenital esophageal atresia, typically associated with tracheoesophageal fistula (EA/TEF). EA/TEF patients are at high risk of having aspiration, and retrospective studies have associated CRM with both recurrent aspiration and atopy. However, studies evaluating the association between CRM in this population and either aspiration or atopy have reported conflicting results. Furthermore, CRM in this population may be due to other related conditions as well, such as tracheomalacia and/or recurrent infections...
2017: Frontiers in Pediatrics
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