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Trigger Finger

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https://www.readbyqxmd.com/read/28919312/the-combined-effects-of-adaptive-control-and-virtual-reality-on-robot-assisted-fine-hand-motion-rehabilitation-in-chronic-stroke-patients-a-case-study
#1
Xianwei Huang, Fazel Naghdy, Golshah Naghdy, Haiping Du, Catherine Todd
Robot-assisted therapy is regarded as an effective and reliable method for the delivery of highly repetitive training that is needed to trigger neuroplasticity following a stroke. However, the lack of fully adaptive assist-as-needed control of the robotic devices and an inadequate immersive virtual environment that can promote active participation during training are obstacles hindering the achievement of better training results with fewer training sessions required. This study thus focuses on these research gaps by combining these 2 key components into a rehabilitation system, with special attention on the rehabilitation of fine hand motion skills...
September 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28902610/transient-vasospastic-response-following-the-injection-of-corticosteroid-into-the-hand
#2
Jacob Tulipan, Kevin Lutsky, Pedro Beredjiklian
A sixty-year-old right hand dominant woman with longstanding left basal joint arthritis and right small trigger finger presented for corticosteroid injections to both areas. She had previously received injections with no adverse effects and good relief of symptoms. Following this most recent injection of corticosteroid, she experienced transient ischemia of the left hand and the right long and ring fingers. Corticosteroid injections can rarely cause local vasospasm, even when not inadvertently injected into the vascular system...
May 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28902606/an-evaluation-of-patient-risk-factors-to-determine-eligibility-to-undergo-orthopaedic-surgery-in-a-freestanding-ambulatory-center-a-survey-of-4-242-consecutive-patients
#3
Matthew Siow, Germaine Cuff, Jovan Popovic, Joseph Bosco
INTRODUCTION: The value proposition of surgery at freestanding ambulatory surgery centers (FSASCs) in terms of efficiency, safety, and patient satisfaction is well established and has led to increased FSASC utilization. However, there are comorbid conditions that disqualify certain patients from surgery at FSASCs. Understanding the percentage of patients whose comorbid conditions exclude them from FSASCs is important for the proper planning and utilization of operating room assets. We aim to understand the percentage of excluded patients, and we predict that certain procedures have higher rates of disqualification due to the types of patients who undergo them...
May 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28902605/trigger-finger-location-and-association-of-comorbidities
#4
Aadit Shah, Michael Rettig
Trigger finger is a common cause of hand pain in the adult population. Studies in the past have suggested that ring finger and thumb are the most prevalent trigger fingers. Risk factors, such as diabetes and hypothyroidism, have been reportedly linked to trigger fingers. This observational prospective study was carried out to identify the most commonly affected trigger finger and observe associated comorbidities. At a single clinical site, a total of 46 patients with 54 trigger fingers on 49 hands were identified over a 7-week period...
May 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28870061/morphological-alterations-of-the-tendon-and-pulley-on-ultrasound-after-intrasynovial-injection-of-betamethasone-for-trigger-digit
#5
Mitsuhiko Takahashi, Ryosuke Sato, Kenji Kondo, Koichi Sairyo
Purpose: The aim of this study was to elucidate whether intrasynovial corticosteroid injections for trigger digit reduced the volume of the tendon and pulley on high-resolution ultrasonography. Methods: Twenty-three digits of 20 patients with trigger digit were included. Each affected finger was graded clinically according to the following classification: grade I for pre-triggering, grade II for active triggering, grade III for passive triggering, and grade IV for presence of contracture...
July 25, 2017: Ultrasonography
https://www.readbyqxmd.com/read/28861151/microrna-204-modulates-chemosensitivity-and-apoptosis-of-prostate-cancer-cells-by-targeting-zinc-finger-e-box-binding-homeobox-1-zeb1
#6
Guanlin Wu, Jian Wang, Guojun Chen, Xing Zhao
Epigenetic gene inactivation by microRNAs (miRNAs) is crucial in malignant transformation, prevention of apoptosis, development of drug resistance, and metastasis. miR-204 dysregulation has been reported in prostate cancer (PC). It is considered to exert tumor suppressor functions and is associated with the development of chemoresistance. However, the detailed mechanisms underlying the role of miR-204 in PC, particularly in chemoresistance, remain to be fully elucidated. In this study, analysis using miRNA microarray showed that miR-204 is downregulated in chemoresistant PC tissues with respect to its expression in chemosensitive PC tissues and benign prostatic hyperplasia tissues...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28860097/effectiveness-of-conservative-surgical-and-post-surgical-interventions-for-trigger-finger-dupuytren-s-disease-and-de-quervain-s-disease-a-systematic-review
#7
REVIEW
Bionka M Huisstede, Saskia Gladdines, Manon S Randsdorp, Bart W Koes
OBJECTIVES: To provide an evidence-based overview of the effectiveness of conservative and (post)-surgical interventions for trigger finger, Dupuytren's -, and De Quervain's disease. DATA SOURCES: The Cochrane Library, PEDro, PubMed, Embase and CINAHL were searched to identify relevant systematic reviews and RCTs. DATA SELECTION AND EXTRACTION: Two reviewers independently extracted the data, and assessed the methodological quality. DATA SYNTHESIS: A best-evidence synthesis was performed to summarize the results...
August 28, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28856358/percutaneous-release-of-trigger-digits
#8
Noah D Weiss, Madeline B Richter
Stenosing flexor tenosynovitis, or trigger finger, has been treated with open, endoscopic, and percutaneous tendon sheath incisions. A comparison of techniques highlights increased cost, procedure time, and postoperative recovery associated with open surgical treatment. We conducted a study of the efficacy of percutaneous tendon sheath incision as a treatment for trigger digit. Using percutaneous tendon sheath incisions, a single surgeon treated 596 trigger digits (429 patients) over a 10-year period. Successful release was defined as symptom relief on follow-up, or patient request for no further treatment...
July 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28853995/hinge-action-versus-grip-in-translocation-by-rna-polymerase
#9
Yuri A Nedialkov, Kristopher Opron, Hailey L Caudill, Fadi Assaf, Amanda J Anderson, Robert I Cukier, Guowei Wei, Zachary F Burton
Based on molecular dynamics simulations and functional studies, a conformational mechanism is posited for forward translocation by RNA polymerase (RNAP). In a simulation of a ternary elongation complex, the clamp and downstream cleft were observed to close. Hinges within the bridge helix and trigger loop supported generation of translocation force against the RNA-DNA hybrid resulting in opening of the furthest upstream i-8 RNA-DNA bp, establishing conditions for RNAP sliding. The β flap tip helix and the most N-terminal β' Zn finger engage the RNA, indicating a path of RNA threading out of the exit channel...
August 30, 2017: Transcription
https://www.readbyqxmd.com/read/28852356/detection-of-retained-foreign-objects-in-upper-extremity-surgical-procedures-with-incisions-of-two-centimeters-or-smaller
#10
Josef N Tofte, Lindsey S Caldwell
BACKGROUND: While the true incidence of retained foreign bodies after surgery is unknown, it has been approximated at 1:5,500 operations overall, with substantially less frequency in hand and upper extremity procedures. Despite the rarity of foreign body retention in hand and upper extremity surgery, universal radiofrequency scanning for electronically-tagged sponges and automatic radiographic evaluation for incorrect sponge counts are employed for all surgical procedures at our institution...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28836453/readability-of-the-most-commonly-accessed-online-patient-education-materials-pertaining-to-pathology-of-the-hand
#11
Sheriff D Akinleye, Garret Garofolo-Gonzalez, Michael Montuori, Maya Deza Culbertson, Jennifer Hashem, David Marc Edelstein
BACKGROUND: The American Medical Association (AMA) and National Institutes of Health (NIH) recommend that patient education materials be written at no higher than a sixth-grade reading level. METHODS: We examined 100 online educational materials for the 10 hand conditions most commonly treated by hand surgeons, as reported by the American Society for Surgery of the Hand. The listed conditions were carpal tunnel syndrome, basal joint arthritis of the thumb, de Quervain syndrome, Dupuytren's contracture, ganglion cysts, hand fractures, trigger finger, extensor tendon injuries, flexor tendon injuries, and mallet finger...
August 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28832206/closed-partial-flexor-digitorum-profundus-rupture-an-unusual-cause-of-pediatric-trigger-finger
#12
Shane R Jackson, Meily Tan, Kim O Taylor
BACKGROUND: Trigger finger is a common condition, causing impaired gliding of the digital flexor tendons. Chronic inflammation is the usual cause, but acute trigger finger following partial tendon laceration has also been described. METHODS: We describe the case of a four year old girl who presented with inability to flex her index finger. Operative exploration revealed a closed partial rupture of the flexor digitorum profundus tendon, catching on the A2 pulley and preventing normal tendon gliding...
September 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28817232/crystal-structure-of-the-melampsora-lini-effector-avrp-reveals-insights-into-a-possible-nuclear-function-and-recognition-by-the-flax-disease-resistance-protein-p
#13
Xiaoxiao Zhang, Nadya Farah, Laura Rolston, Daniel J Ericsson, Ann-Maree Catanzariti, Maud Bernoux, Thomas Ve, Katerina Bendak, Chunhong Chen, Joel P Mackay, Gregory J Lawrence, Adrienne Hardham, Jeffrey G Ellis, Simon J Williams, Peter N Dodds, David A Jones, Bostjan Kobe
The effector protein AvrP is secreted by the flax rust fungal pathogen (Melampsora lini) and recognized specifically by the flax (Linum usitatissimum) P disease resistance protein, leading to effector-triggered immunity. To investigate the biological function of this effector and mechanisms of specific recognition by the P resistance protein, we determined the crystal structure of AvrP. The structure reveals an elongated zinc-finger-like structure with a novel interleaved zinc-binding topology. The residues responsible for zinc binding are conserved in AvrP effector variants and mutations of these motifs result in loss of P-mediated recognition...
August 17, 2017: Molecular Plant Pathology
https://www.readbyqxmd.com/read/28811061/surgical-demographics-of-carpal-tunnel-syndrome-and-cubital-tunnel-syndrome-over-5-years-at-a-single-institution
#14
Dafang Zhang, Jamie E Collins, Brandon E Earp, Philip Blazar
PURPOSE: Carpal tunnel and cubital tunnel syndrome are the 2 most common upper-limb compressive neuropathies. However, whether the characteristics of patient populations undergoing surgery for these conditions are similar is unclear in terms of demographics and concomitant pathologies. Our null hypothesis was that there are no identifiable differences between these patient populations. METHODS: A retrospective cohort study was performed by billing system query using Common Procedural Terminology (CPT) codes for all patients who underwent open carpal tunnel release (CTR) (CPT code 64721) and/or open cubital tunnel surgery (CPT code 64718) by 1 of 4 hand surgeons from August 2008 to July 2013...
August 12, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28802536/incidence-of-glove-perforation-during-hand-surgical-procedures
#15
Kevin F Lutsky, Christopher Jones, Jack Abboudi, William Kirkpatrick, Fred Liss, Charles Leinberry, Asif Ilyas, Dennis Martin, Pedro K Beredjiklian
PURPOSE: To determine the rate of glove perforation during hand surgery. METHODS: We prospectively examined the rate of glove perforations among 10 fellowship-trained hand surgeons at our institution during a 6 week period. Gloves were tested for perforation using a water-fill technique at the conclusion of each surgical procedure. Surgeons recorded the presence of any glove perforations. RESULTS: Eleven perforations were identified in 10 gloves among 600 surgical procedures during the study period...
August 9, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28802438/investigation-of-index-finger-triggering-force-using-a-cadaver-experiment-effects-of-trigger-grip-span-contact-location-and-internal-tendon-force
#16
Joonho Chang, Andris Freivalds, Neil A Sharkey, Yong-Ku Kong, H Mike Kim, Kiseok Sung, Dae-Min Kim, Kihyo Jung
A cadaver study was conducted to investigate the effects of triggering conditions (trigger grip span, contact location, and internal tendon force) on index finger triggering force and the force efficiency of involved tendons. Eight right human cadaveric hands were employed, and a motion simulator was built to secure and control the specimens. Index finger triggering forces were investigated as a function of different internal tendon forces (flexor digitorum profundus + flexor digitorum superficialis = 40, 70, and 100 N), trigger grip spans (40, 50, and 60 mm), and contact locations between the index finger and a trigger...
November 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28791721/cortical-control-of-object-specific-grasp-relies-on-adjustments-of-both-activity-and-effective-connectivity-a-common-marmoset-study
#17
Banty Tia, Mitsuaki Takemi, Akito Kosugi, Elisa Castagnola, Alberto Ansaldo, Takafumi Nakamura, Davide Ricci, Junichi Ushiba, Luciano Fadiga, Atsushi Iriki
The cortical mechanisms of grasping have been extensively studied in macaques and humans. Here, we investigated whether common marmosets could rely on similar mechanisms despite striking differences in manual dexterity. Two common marmosets were trained to grasp-and-pull three objects eliciting different hand configurations: whole-hand, finger and scissor grips. The animals were then chronically implanted with 64-channel electrocorticogram arrays positioned over the left premotor, primary motor and somatosensory cortex...
August 9, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28774233/disruption-of-flexor-tendon-after-intrasheath-triamcinolone-acetonide-injection-for-trigger-digits-two-case-reports
#18
Toshikazu Tanaka, Takeshi Ogawa, Takaji Yanai, Eriko Okano, Sho Kohyama, Naoyuki Ochiai
We experienced two cases of flexor tendons rupture after triamcinolone acetate (TA) injection for trigger finger. A 45-year-old man underwent injection of 40 mg of TA and 1 mL of 1% lidocaine solution into his little finger. While playing golf 3 months after the injection, he heard a popping sound, and was unable to flex it. A 57-year-old female nurse had undergone injection of 40 mg of TA and 1 mL of 1% lidocaine solution into her thumb twice at a 2-month interval. Two months after the second injection, she was unable to flex it...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28743050/pml-rar%C3%AE-stabilized-by-zinc-in-human-acute-promyelocytic-leukemia-nb4-cells
#19
Bo Zhu, Jia-Yu Wang, Jun-Jie Zhou, Feng Zhou, Wei Cheng, Ying-Ting Liu, Jie Wang, Xiao Chen, Dian-Hua Chen, Lan Luo, Zi-Chun Hua
Acute promyelocytic leukemia (APL) is characterized and driven by the promyelocytic leukemia protein-retinoic acid receptor alpha (PML-RARα) fusion gene. Previous studies have highlighted the importance of PML-RARα degradation in the treatment against APL. Considering the presence of two zinc fingers in the PML-RARα fusion protein, we explored the function of zinc homeostasis in maintaining PML-RARα stability. We demonstrated for the first time that zinc depletion by its chelator N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) triggered PML-RARα degradation in NB4 APL cells via the proteasome pathway rather than the autophagy-lysosomal pathway...
July 19, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28732896/a-hydrogel-actuator-with-flexible-folding-deformation-and-shape-programming-via-using-sodium-carboxymethyl-cellulose-and-acrylic-acid
#20
Shuiping Wu, Feng Yu, Hua Dong, Xiaodong Cao
Hydrogel actuator is an intelligent material, which can work as artificial muscle. However, most present hydrogel actuators, due to the inferior mechanical property and uncontrolled folding property, have always resulted in slipping off or the failure of grasping an object with specific shape and required weight. In order to solve this problem, here a tough hydrogel actuator with programmable folding deformation has been prepared by combining the "selective implanting method" and "ionic coordination". The shape and folding angle (from 0 to 180 (o)) of hydrogel actuator can be precisely controlled by altering the location and size of the implanting parts that seems like the joints of finger...
October 1, 2017: Carbohydrate Polymers
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