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Trigger Finger

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https://www.readbyqxmd.com/read/28094976/breath-figure-micromolding-approach-for-regulating-the-microstructures-of-polymeric-films-for-triboelectric-nanogenerators
#1
Jianliang Gong, Bingang Xu, Xiaoming Tao
Triboelectric nanogenerator (TENG) is an innovative kind of energy harvester recently developed based on organic materials for converting mechanical energy into electricity through the conjunction use of triboelectric effect and electrostatic induction. Polymeric materials and their microstructures play key roles in the generation, accumulation, and retainment of triboelectric charges, which decisively determines the final electric performance of TENGs. Herein we report a simple and efficient breath figure micromolding approach to rapidly regulate the surface microstructures of polymeric films for the assembly of TENGs...
January 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28071597/three-dimensional-printing-of-a-microneedle-array-on-personalized-curved-surfaces-for-dual-pronged-treatment-of-trigger-finger
#2
Seng Han Lim, Jian Yao Ng, Lifeng Kang
The hand function of patients who suffer from trigger finger can be impaired by the use of traditional splints. There is also a risk of systemic side effects with oral non-steroidal anti-inflammatory drugs (NSAIDs) used for pain relief. Microneedle-assisted transdermal drug delivery offers an attractive alternative for local delivery of NSAIDs. However, traditional microneedle arrays fabricated on flat surfaces are unable to deliver drugs effectively across the undulating skin surface of affected finger(s)...
January 10, 2017: Biofabrication
https://www.readbyqxmd.com/read/28067854/quantitative-assessment-of-first-annular-pulley-and-adjacent-tissues-using-high-frequency-ultrasound
#3
Yi-Hsun Lin, Tai-Hua Yang, Shyh-Hau Wang, Fong-Chin Su
Due to a lack of appropriate image resolution, most ultrasound scanners are unable to sensitively discern the pulley tissues. To extensively investigate the properties of the A1 pulley system and the surrounding tissues for assessing trigger finger, a 30 MHz ultrasound system was implemented to perform in vitro experiments using the hypodermis, A1 pulley, and superficial digital flexor tendon (SDFT) dissected from cadavers. Ultrasound signals were acquired from both the transverse and sagittal planes of each tissue sample...
January 7, 2017: Sensors
https://www.readbyqxmd.com/read/28008672/the-angulata7-gene-encodes-a-dnaj-like-zinc-finger-domain-protein-involved-in-chloroplast-function-and-leaf-development-in-arabidopsis
#4
Tamara Muñoz-Nortes, José Manuel Pérez-Pérez, María Rosa Ponce, Héctor Candela, José Luis Micol
The characterization of mutants with altered leaf shape and pigmentation has previously allowed the identification of nuclear genes that encode plastid-localized proteins that perform essential functions in leaf growth and development. A large-scale screen previously allowed us to isolate ethyl methanesulfonate-induced mutants with small rosettes and pale green leaves with prominent marginal teeth, which were assigned to a phenotypic class that we dubbed Angulata. The molecular characterization of the twelve genes assigned to this phenotypic class should help us to advance our understanding of the still poorly understood relationship between chloroplast biogenesis and leaf morphogenesis...
December 23, 2016: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28002865/percutaneous-release-procedures-trigger-finger-and-carpal-tunnel
#5
Gajan Rajeswaran, Jeremiah C Healy, Justin C Lee
Trigger digit and carpal tunnel syndrome are both conditions traditionally treated with open surgery but are potentially amenable to curative treatment using percutaneous techniques. The advantages of minimally invasive techniques are lower risk of wound breakdown and infection, quicker healing, reduced postprocedural pain, reduced complications, and a quicker return to normal activity. The advent of high-resolution ultrasound has allowed percutaneous release procedures for these conditions to be developed and performed with a potential for a reduced risk of complications and an increased likelihood of success...
November 2016: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/28002861/injectable-corticosteroids-take-precautions-and-use-caution
#6
Véronique Freire, Nathalie J Bureau
Corticosteroids are routinely injected into soft tissues, tendon sheaths, bursae, and joints. These anti-inflammatory agents have different potency and solubility, and solubility is inversely correlated with the duration of action. Corticosteroids carry a low risk of complications but commonly cause systemic and local adverse effects. The use of intra-articular corticosteroid injections in the treatment of inflammatory arthritis and osteoarthritis is well established. Evidence also supports the use of injectable corticosteroids in the treatment of inflammatory tenosynovitis and bursitis associated with rheumatic diseases, trigger finger and de Quervain disease, and carpal tunnel syndrome...
November 2016: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/28002675/flexible-all-inorganic-actuators-based-on-vanadium-dioxide-and-carbon-nanotube-bimorphs
#7
He Ma, Jiwei Hou, Xuewen Wang, Jin Zhang, Zhiquan Yuan, Lin Xiao, Yang Wei, Shoushan Fan, Kaili Jiang, Kai Liu
Flexible actuators responsive to multiple stimuli are much desired in wearable electronics. However, general designs containing organic materials are usually subject to slow response and limited lifetime, or high triggering threshold. In this study, we develop flexible, all-inorganic actuators based on bimorph structures composed of vanadium dioxide (VO2) and carbon nanotube (CNT) thin films. The drastic, reversible phase transition of VO2 drives the actuators to deliver giant amplitude, fast response up to ∼100 Hz, and long lifetime more than 1 000 000 actuation cycles...
December 27, 2016: Nano Letters
https://www.readbyqxmd.com/read/27979461/evaluating-the-reliability-of-equilibrium-dissolution-assumption-from-residual-gasoline-in-contact-with-water-saturated-sands
#8
Greg Lekmine, Kaveh Sookhak Lari, Colin D Johnston, Trevor P Bastow, John L Rayner, Greg B Davis
Understanding dissolution dynamics of hazardous compounds from complex gasoline mixtures is a key to long-term predictions of groundwater risks. The aim of this study was to investigate if the local equilibrium assumption for BTEX and TMBs (trimethylbenzenes) dissolution was valid under variable saturation in two dimensional flow conditions and evaluate the impact of local heterogeneities when equilibrium is verified at the scale of investigation. An initial residual gasoline saturation was established over the upper two-thirds of a water saturated sand pack...
January 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/27955967/digital-necrosis-after-lidocaine-and-epinephrine-injection-in-the-flexor-tendon-sheath-without-phentolamine-rescue
#9
Jacques X Zhang, Jason Gray, Donald H Lalonde, Nicholas Carr
The literature generally supports the safety of epinephrine injection in the digits, but recent case reports describe ischemic adverse events associated with the use of lidocaine and epinephrine in which phentolamine rescue was not performed. We present a case of finger necrosis and subsequent amputation in a patient after 1% lidocaine with 1:100,000 epinephrine was injected in the fat and flexor sheaths in the palm for a 3-finger trigger release. Phentolamine rescue was not performed. All surgeons who use epinephrine in the finger should be prepared to reverse vasoconstriction with phentolamine rescue if there is persistently inadequate perfusion of the fingertip...
December 9, 2016: Journal of Hand Surgery
https://www.readbyqxmd.com/read/27940039/management-strategy-for-congenital-thumb-differences-in-paediatric-patients
#10
REVIEW
G Dautel
Congenital thumb anomalies are common and have a major impact given the specific functional role of the thumb. They may occur alone or as part of a multiple congenital anomaly syndrome. The primary goal of surgical management is to improve or restore pincer grip. In patients with 'congenital' trigger thumb, the A1 pulley must be released if the interphalangeal joint remains in fixed flexion. Thumb duplication is generally managed by reconstruction of the thumb from the predominant (ulnar-based) digit; the accessory (radial-based) digit is excised after collection of its tissue components needed for the reconstruction programme...
December 8, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27914614/outcomes-of-percutaneous-trigger-finger-release%C3%A2-with-concurrent-steroid-injection
#11
Wen-Chih Liu, Chun-Kuan Lu, Yu-Chuan Lin, Peng-Ju Huang, Gau-Tyan Lin, Yin-Chih Fu
Percutaneous release (PR) of the A1 pulley is a quick, safe, and minimally invasive procedure for treating trigger fingers. The purpose of this study is to identify if PR with additional steroid injections can shorten the recovery to reach unlimited range of motion. Between January 2013 and December 2013, we included 432 trigger fingers with actively correctable triggering or severer symptoms without previous surgical release or steroid injections from two hand clinic offices (A and B). The same experienced surgeon performed PR at the office...
December 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27913950/mechanics-reveals-the-biological-trigger-in-wrinkly-fingers
#12
P Sáez, A M Zöllner
Fingertips wrinkle due to long exposure to water. The biological reason for this morphological change is unclear and still not fully understood. There are two main hypotheses for the underlying mechanism of fingertip wrinkling: the 'shrink' model (in which the wrinkling is driven by the contraction of the lower layers of skin, associated with the shrinking of the underlying vasculature), and the 'swell' model (in which the wrinkling is driven by the swelling of the upper layers of the skin, associated with osmosis)...
December 2, 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/27880725/mouse-sirt3-promotes-autophagy-in-angii-induced-myocardial-hypertrophy-through-the-deacetylation-of-foxo1
#13
Jingyuan Li, Tongshuai Chen, Ming Xiao, Na Li, Shujian Wang, Hongyan Su, Xiaobin Guo, Hui Liu, Fangying Yan, Yi Yang, Yun Zhang, Peili Bu
Sirt3, a mitochondrial NAD+-dependent histone deacetylase, is the only member proven to promote longevity in mammalian Sirtuin family. The processed short form of Sirt3 has been demonstrated to target many mediators of energy metabolism and mitochondrial stress adaptive program. Autophagy serves as a dynamic recycling mechanism and provides energy or metabolic substrates. Among the mechanisms triggered by cardiac stress, opinions vary as to whether autophagy is a protective or detrimental response. Here, by inducing the Sirt3-knockout mice to myocardial hypertrophy with chronic angiotensin II infusion for four weeks, we determined the role of Sirt3 in myocardial hypertrophy and autophagy...
November 17, 2016: Oncotarget
https://www.readbyqxmd.com/read/27847849/assessment-of-decisional-conflict-about-the-treatment-of-trigger-finger-comparing-patients-and-physicians
#14
Michiel G J S Hageman, Anne-Carolin Döring, Silke A Spit, Thierry G Guitton, David Ring
BACKGROUND: As an early step in the development of a decision aid for idiopathic trigger finger (TF) we were interested in the level of decisional conflict experienced by patients and hand surgeons. This study tested the null hypothesis that there is no difference in decisional conflict between patients with one or more idiopathic trigger fingers and hand surgeons. Secondary analyses address the differences between patients and surgeons regarding the influence of the DCS-subcategories on the level of decisional conflict, as well as the influence of patient and physician demographics, the level of self-efficacy, and satisfaction with care on decisional conflict...
October 2016: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/27843364/radial-extracorporeal-shockwave-therapy-for-the-treatment-of-finger-tenosynovitis-trigger-digit
#15
Nikos Malliaropoulos, Rosanna Jury, Debasish Pyne, Nat Padhiar, Jennifer Turner, Vasileios Korakakis, Maria Meke, Heinz Lohrer
INTRODUCTION: Stenosing tenosynovitis that is characterized by the inability to flex the digit smoothly, usually leads to prolonged rehabilitation or surgery. STUDY DESIGN: This case series is a retrospective cohort study. PURPOSE: The aim of this case series was to evaluate the effectiveness of radial extracorporeal shockwave therapy (rESWT) for the treatment of stenosing tenosynovitis of the digital flexor tendon (trigger digit). METHODS: A retrospective analysis of 44 patients (49 fingers) treated with an individually adapted rESWT protocol was conducted...
2016: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/27830943/long-term-functional-outcome-of-trigger-finger
#16
Danit Langer, Shai Luria, Michael Michailevich, Adina Maeir
PURPOSE: The purpose of this study was to explore the long-term functional outcomes of trigger finger (TF) as perceived by the patient. METHODS: Three study groups were included in the study: prolonged follow up TF group (at least 1-year post-treatment) (PF-TF), patients with acute TF and a control group. The first group was recruited retrospectively and included all patients who were diagnosed with TF in one orthopedic clinic and were contacted by phone, 109 agreed to participate...
November 10, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27830829/cellulase-from-trichoderma-harzianum-interacts-with-roots-and-triggers-induced-systemic-resistance-to-foliar-disease-in-maize
#17
Kandasamy Saravanakumar, Lili Fan, Kehe Fu, Chuanjin Yu, Meng Wang, Hai Xia, Jianan Sun, Yaqian Li, Jie Chen
Trichoderma harzianum is well known to exhibit induced systemic resistance (ISR) to Curvularia leaf spot. We previously reported that a C6 zinc finger protein (Thc6) is responsible for a major contribution to the ISR to the leaf disease, but the types of effectors and the signals mediated by Thc6 from Trichoderma are unclear. In this work, we demonstrated that two hydrolases, Thph1 and Thph2, from T. harzianum were regulated by Thc6. Furthermore, an electrophoretic mobility shift assay (EMSA) study revealed that Thc6 regulated mRNA expression by binding to GGCTAA and GGCTAAA in the promoters of the Thph1 and Thph2 genes, respectively...
November 10, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27826738/transcription-factor-pex1-modulates-extracellular-matrix-turnover-through-regulation-of-mmp-9-expression
#18
Alicia Jurado Acosta, Jaana Rysä, Zoltan Szabo, Anne-Mari Moilanen, Hiba Komati, Mona Nemer, Heikki Ruskoaho
The phenylephrine-induced complex-1 (PEX1) transcription factor, also known as zinc-finger protein 260 (Zfp260), is an effector of endothelin-1 and α1-adrenergic signaling in cardiac hypertrophy. However, the role of PEX1 in transcriptional regulation of myocardial remodeling remains largely unknown. In the present study, we used PEX1 gain- and loss-of-function to examine the effects of PEX1 on left ventricular remodeling. Adenoviral constructs expressing PEX1, antisense PEX1, or LacZ were delivered by local injection into the anterior wall of the left ventricle in Sprague-Dawley rats...
November 8, 2016: Cell and Tissue Research
https://www.readbyqxmd.com/read/27817941/trigger-finger-caused-by-extraskeletal-chondroma
#19
Karl Schwaiger, Florian Ensat, Daniel Neurreiter, Gottfried Wechselberger, Michaela Hladik
Chondroma is a relatively rare, but well-reported benign neoplasm. This lesion normally occurs attached to bone; however, they may be rarely found without association to bone and embedded in soft tissue. The authors describe the case of a 76-year-old man in whom flexor tendon triggering was associated with an extraskeletal chondroma between the annular ligament and the flexor tendon.
November 3, 2016: Journal of Hand Surgery
https://www.readbyqxmd.com/read/27816777/concurrent-use-of-somatotopic-and-external-reference-frames-in-a-tactile-mislocalization-task
#20
Luigi Tamè, Anja Wühle, Caroline D Petri, Francesco Pavani, Christoph Braun
Localizing tactile stimuli on our body requires sensory information to be represented in multiple frames of reference along the sensory pathways. These reference frames include the representation of sensory information in skin coordinates, in which the spatial relationship of skin regions is maintained. The organization of the primary somatosensory cortex matches such somatotopic reference frame. In contrast, higher-order representations are based on external coordinates, in which body posture and gaze direction are taken into account in order to localise touch in other meaningful ways according to task demands...
February 2017: Brain and Cognition
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