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Mobile phone RCT

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https://www.readbyqxmd.com/read/29411270/haptoglobin-genotype-and-vitamin%C3%A2-e-versus-placebo-for-the-treatment-of-nondiabetic-patients-with-nonalcoholic-steatohepatitis-in-china-a-multicenter-randomized-placebo-controlled-trial-design
#1
Shufei Zang, Jin Chen, Yu Song, Lang Bai, Jinjun Chen, Xiaoling Chi, Fangping He, Huiping Sheng, Jing Wang, Shilong Xie, Wen Xie, Yongfeng Yang, Jing Zhang, Minghua Zheng, Zhengsheng Zou, Bingyuan Wang, Junping Shi
INTRODUCTION: Vitamin E is one of the most promising agents for nonalcoholic steatohepatitis (NASH) treatment, and its drug responsiveness may be closely associated with haptoglobin (Hp) genotype. However, its efficacy and safety remain unknown in China. This clinical trial of vitamin E versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis (VENS) is conducted to evaluate (a) the efficacy and safety of treatment with vitamin E softgel (300 mg/day) determined from standardized histologic scoring of liver biopsies, (b) whether treatment with vitamin E improves biochemical parameters, cytokines, anthropometric parameters, controlled attenuation parameter (CAP), and transient elastography (TE) values determined by Fibroscan and health-related quality of life (SF-36), (c) whether the efficacy of vitamin E treatment is associated with the Hp genotype in nondiabetic adults with NASH...
February 6, 2018: Advances in Therapy
https://www.readbyqxmd.com/read/29371177/evaluating-machine-learning-based-automated-personalized-daily-step-goals-delivered-through-a-mobile-phone-app-randomized-controlled-trial
#2
Mo Zhou, Yoshimi Fukuoka, Yonatan Mintz, Ken Goldberg, Philip Kaminsky, Elena Flowers, Anil Aswani
BACKGROUND: Growing evidence shows that fixed, nonpersonalized daily step goals can discourage individuals, resulting in unchanged or even reduced physical activity. OBJECTIVE: The aim of this randomized controlled trial (RCT) was to evaluate the efficacy of an automated mobile phone-based personalized and adaptive goal-setting intervention using machine learning as compared with an active control with steady daily step goals of 10,000. METHODS: In this 10-week RCT, 64 participants were recruited via email announcements and were required to attend an initial in-person session...
January 25, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29184891/the-role-of-mhealth-intervention-on-maternal-and-child-health-service-delivery-findings-from-a-randomized-controlled-field-trial-in-rural-ethiopia
#3
Asfaw Atnafu, Kate Otto, Christopher H Herbst
Background: The provision of consistent and quality maternal and child health (MCH) services is a challenge for Ethiopia where most of the population lives in the rural setup. Health service delivery is constrained mainly by shortage of health professionals, meager resources, limited awareness among the society and bureaucratic procedures. Low health service utilization of antenatal care (ANC), delivery services, and postnatal care (PNC) are believed to contribute for high maternal and child mortality rates...
2017: MHealth
https://www.readbyqxmd.com/read/29132364/-i-m-not-strong-enough-i-m-not-good-enough-i-can-t-do-this-i-m-failing-a-qualitative-study-of-low-socioeconomic-status-smokers-experiences-with-accesssing-cessation-support-and-the-role-for-alternative-technology-based-support
#4
Veronica C Boland, Richard P Mattick, Hayden McRobbie, Mohammad Siahpush, Ryan J Courtney
BACKGROUND: The social gradient in smoking rates persist with an overrepresentation of smoking and its associated harms concentrated within lower socioeconomic status (SES) populations. Low-SES smokers are motivated to quit but face multiple barriers when engaging a quit attempt. An understanding of the current treatment service model from the perspectives of treatment-seeking low-SES smokers is needed to inform the design of alternative smoking cessation support services tailored to the needs of low-SES populations...
November 13, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29073916/participant-recruitment-and-retention-in-longitudinal-preconception-randomized-trials-lessons-learnt-from-the-calcium-and-pre-eclampsia-cap-trial
#5
Theresa A Lawrie, Ana Pilar Betrán, Mandisa Singata-Madliki, Alvaro Ciganda, G Justus Hofmeyr, José M Belizán, Tina Dannemann Purnat, Sarah Manyame, Catherine Parker, Gabriela Cormick
BACKGROUND: The preconception period has the potential to influence pregnancy outcomes and randomized controlled trials (RCTs) are needed to evaluate a variety of potentially beneficial preconception interventions. However, RCTs commencing before pregnancy have significant participant recruitment and retention challenges. The Calcium And Pre-eclampsia trial (CAP trial) is a World Health Organization multi-country RCT of calcium supplementation commenced before pregnancy to prevent recurrent pre-eclampsia in which non-pregnant participants are recruited and followed up until childbirth...
October 26, 2017: Trials
https://www.readbyqxmd.com/read/28928110/perceptions-of-patients-with-chronic-obstructive-pulmonary-disease-and-their-physiotherapists-regarding-the-use-of-an-ehealth-intervention
#6
Sigrid Vorrink, Chantal Huisman, Helianthe Kort, Thierry Troosters, Jan-Willem Lammers
BACKGROUND: If eHealth interventions are not used (properly), their potential benefits cannot be fulfilled. User perceptions of eHealth are an important determinant of its successful implementation. This study examined how patients with chronic obstructive pulmonary disease (COPD) and their physiotherapists (PHTs) value an eHealth self-management intervention following a period of use. OBJECTIVE: The study aimed to evaluate the perceptions of COPD patients and their PHTs as eHealth users...
September 19, 2017: JMIR Human Factors
https://www.readbyqxmd.com/read/28659252/mobile-phone-short-messages-to-improve-exclusive-breastfeeding-and-reduce-adverse-infant-feeding-practices-protocol-for-a-randomized-controlled-trial-in-yangon-myanmar
#7
Myat Pan Hmone, Mu Li, Ashraful Alam, Michael J Dibley
BACKGROUND: Myanmar has a high burden of mortality for children aged younger than 5 years in which undernutrition plays a major role. Despite current efforts, the exclusive breastfeeding rate for children under 6 months is only 24%. To date there have been no interventions using mobile phones to improve breastfeeding and other feeding practices in Myanmar. OBJECTIVE: This study aims to implement a breastfeeding promotion intervention using mobile phone text messages in Yangon, Myanmar, and evaluate its impact on breastfeeding practices...
June 28, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28630037/a-mobile-app-for-the-self-management-of-type-1-diabetes-among-adolescents-a-randomized-controlled-trial
#8
Shivani Goyal, Caitlin A Nunn, Michael Rotondi, Amy B Couperthwaite, Sally Reiser, Angelo Simone, Debra K Katzman, Joseph A Cafazzo, Mark R Palmert
BACKGROUND: While optimal blood glucose control is known to reduce the long-term complications associated with type 1 diabetes mellitus, adolescents often struggle to achieve their blood glucose targets. However, their strong propensity toward technology presents a unique opportunity for the delivery of novel self-management interventions. To support type 1 diabetes self-management in this population, we developed the diabetes self-management app bant, which included wireless blood glucose reading transfer, out-of-range blood glucose trend alerts, coaching around out-of-range trend causes and fixes, and a point-based incentive system...
June 19, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28520768/mobile-phone-reminders-and-peer-counseling-improve-adherence-and-treatment-outcomes-of-patients-on-art-in-malaysia-a-randomized-clinical-trial
#9
RANDOMIZED CONTROLLED TRIAL
Surajudeen Abiola Abdulrahman, Lekhraj Rampal, Faisal Ibrahim, Anuradha P Radhakrishnan, Hayati Kadir Shahar, Norlijah Othman
BACKGROUND: Adherence to treatment remains the cornerstone of long term viral suppression and successful treatment outcomes among patients receiving Antiretroviral Therapy (ART). OBJECTIVE(S): Evaluate the effectiveness of mobile phone reminders and peer counseling in improving adherence and treatment outcomes among HIV positive patients on ART in Malaysia. METHODS: A single-blind, parallel group RCT conducted in Hospital Sungai Buloh, Malaysia in which 242 adult Malaysian patients were randomized to intervention or control groups...
2017: PloS One
https://www.readbyqxmd.com/read/28494802/reducing-depressive-symptomatology-with-a-smartphone-app-study-protocol-for-a-randomized-placebo-controlled-trial
#10
Cezar Giosan, Oana Cobeanu, Cristina Mogoaşe, Aurora Szentagotai, Vlad Mureşan, Rareș Boian
BACKGROUND: Depression has become one of the leading contributors to the global disease burden. Evidence-based treatments for depression are available, but access to them is still limited in some instances. As technology has become more integrated into mental health care, computerized cognitive behavioral therapy (CBT) protocols have become available and have been recently transposed to mobile environments (e.g., smartphones) in the form of "apps." Preliminary research on some depression apps has shown promising results in reducing subthreshold or mild to moderate depressive symptoms...
May 12, 2017: Trials
https://www.readbyqxmd.com/read/28465278/text-message-feedback-to-support-mindfulness-practice-in-people-with-depressive-symptoms-a-pilot-randomized-controlled-trial
#11
Susanne Kraft, Markus Wolf, Thomas Klein, Thomas Becker, Stephanie Bauer, Bernd Puschner
BACKGROUND: It has been shown that mindfulness practice can be helpful in preventing relapse from depression. However, practicing mindfulness regularly at home is often a challenge for people with depression. Mobile phone text messaging (short message service, SMS) may be a feasible approach to assist regular mindfulness home practice. OBJECTIVE: The aim of this study was to evaluate the feasibility of text message-based feedback to support mindfulness practice in people with depressive symptoms after inpatient psychiatric treatment...
May 2, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28446419/the-smartphone-peer-physical-activity-counseling-sppac-program-for-manual-wheelchair-users-protocol-of-a-pilot-randomized-controlled-trial
#12
Krista L Best, François Routhier, Shane N Sweet, Kelly P Arbour-Nicitopoulos, Jaimie F Borisoff, Luc Noreau, Kathleen A Martin Ginis
BACKGROUND: Physical activity (PA) must be performed regularly to accrue health benefits. However, the majority of manual wheelchair users do not meet PA recommendations. Existing community-based PA programs for manual wheelchair users appear to work, but effect sizes are small and retention is low. Existing PA programs may not fully implement some psychosocial factors that are strongly linked with PA (eg, autonomy). The use of peers and mobile phone technology in the Smartphone Peer PA Counseling (SPPAC) program represents a novel approach to cultivating a PA-supportive environment for manual wheelchair users...
April 26, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28419149/mobile-health-treatment-support-intervention-for-hiv-and-tuberculosis-in-mozambique-perspectives-of-patients-and-healthcare-workers
#13
RANDOMIZED CONTROLLED TRIAL
José António Nhavoto, Åke Grönlund, Gunnar O Klein
BACKGROUND: Studies have been conducted in developing countries using SMS to communicate with patients to reduce the number of missed appointments and improve retention in treatment, however; very few have been scaled up. One possible reason for this could be that patients or staff are dissatisfied with the method in some way. This paper reports a study of patients' and healthcare workers' (HCW) views on an mHealth intervention aiming to support retention in antiretroviral therapy (ART) and tuberculosis (TB) treatment in Mozambique...
2017: PloS One
https://www.readbyqxmd.com/read/28264692/a-three-component-cognitive-behavioural-lifestyle-program-for-preconceptional-weight-loss-in-women-with-polycystic-ovary-syndrome-pcos-a-protocol-for-a-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
G Jiskoot, S H Benneheij, A Beerthuizen, J E de Niet, C de Klerk, R Timman, J J Busschbach, J S E Laven
BACKGROUND: Obesity in women with polycystic ovary syndrome (PCOS) negatively affects all clinical features, and a 5 to 10% weight loss has shown promising results on reproductive, metabolic and psychological level. Incorporating a healthy diet, increasing physical activity and changing dysfunctional thought patterns in women with PCOS are key points in losing weight. The biggest challenge in weight management programs is to achieve a reasonable and sustainable weight loss. The aim of this study is to explore whether Cognitive Behavioural Therapy (CBT) by a mental health professional, working in a multidisciplinary team with a dietician and a physical therapist (a three-component intervention), is more effective for weight loss in the long term, within 12 months...
March 6, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28213632/preventing-weight-gain-improves-sleep-quality-among-black-women-results-from-a-rct
#15
Dori M Steinberg, Jacob Christy, Bryan C Batch, Sandy Askew, Reneé H Moore, Portia Parker, Gary G Bennett
BACKGROUND: Obesity and poor sleep are highly prevalent among Black women. PURPOSE: We examined whether a weight gain prevention intervention improved sleep among Black women. METHODS: We conducted a randomized trial comparing a 12-month weight gain prevention intervention that included self-monitoring through mobile technologies and phone coaching to usual care in community health centers. We measured sleep using the Medical Outcomes Study Sleep Scale at baseline, 12 months, and 18 months...
February 17, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/27965823/feasibility-of-a-stepped-wedge-cluster-rct-and-concurrent-observational-sub-study-to-evaluate-the-effects-of-modified-ward-night-lighting-on-inpatient-fall-rates-and-sleep-quality-a-protocol-for-a-pilot-trial
#16
Satyan R Chari, Simon Smith, Alison Mudge, Alex A Black, Mariana Figueiro, Muhtashimuddin Ahmed, Mark Devitt, Terry P Haines
BACKGROUND: Falls among hospitalised patients impose a considerable burden on health systems globally and prevention is a priority. Some patient-level interventions have been effective in reducing falls, but others have not. An alternative and promising approach to reducing inpatient falls is through the modification of the hospital physical environment and the night lighting of hospital wards is a leading candidate for investigation. In this pilot trial, we will determine the feasibility of conducting a main trial to evaluate the effects of modified night lighting on inpatient ward level fall rates...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27608829/development-of-a-mobile-phone-based-weight-loss-lifestyle-intervention-for-filipino-americans-with-type-2-diabetes-protocol-and-early-results-from-the-pilam-go4health-randomized-controlled-trial
#17
Melinda Sarmiento Bender, Glenn-Milo Santos, Carissa Villanueva, Shoshana Arai
BACKGROUND: Filipino Americans are the second largest Asian subgroup in the United States, and were found to have the highest prevalence of obesity and type 2 diabetes (T2D) compared to all Asian subgroups and non-Hispanic whites. In addition to genetic factors, risk factors for Filipinos that contribute to this health disparity include high sedentary rates and high fat diets. However, Filipinos are seriously underrepresented in preventive health research. Research is needed to identify effective interventions to reduce Filipino diabetes risks, subsequent comorbidities, and premature death...
September 8, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27548504/understanding-the-importance-of-context-a-qualitative-study-of-a-location-based-exergame-to-enhance-school-childrens-physical-activity
#18
Judy Robertson, Ruth Jepson, Andrew Macvean, Stuart Gray
Many public health interventions are less effective than expected in 'real life settings', yet little work is undertaken to understand the reasons why. The effectiveness of complex public health interventions can often be traced back to a robust programme theory (how and why an intervention brings about a change in outcome(s)) and assumptions that are made about the context in which it is implemented. Understanding whether effectiveness (or lack thereof) is due to the intervention or the context is hugely helpful in decisions about whether to a) modify the intervention; b) modify the context; c) stop providing the intervention...
2016: PloS One
https://www.readbyqxmd.com/read/27542325/evaluation-of-a-behavioral-mobile-phone-app-intervention-for-the-self-management-of-type-2-diabetes-randomized-controlled-trial-protocol
#19
Shivani Goyal, Gary Lewis, Catherine Yu, Michael Rotondi, Emily Seto, Joseph A Cafazzo
BACKGROUND: Patients with type 2 diabetes mellitus (T2DM) struggle with the management of their condition due to difficulty relating lifestyle behaviors with glycemic control. While self-monitoring of blood glucose (SMBG) has proven to be effective for those treated with insulin, it has been shown to be less beneficial for those only treated with oral medications or lifestyle modification. We hypothesized that the effective self-management of non-insulin treated T2DM requires a behavioral intervention that empowers patients with the ability to self-monitor, understand the impact of lifestyle behaviors on glycemic control, and adjust their self-care based on contextualized SMBG data...
August 19, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27535717/protocol-for-a-randomized-controlled-trial-evaluating-mobile-text-messaging-to-promote-retention-and-adherence-to-antiretroviral-therapy-for-people-living-with-hiv-in-burkina-faso
#20
Natascha Wagner, Denis Ouedraogo, Luis Artavia-Mora, Arjun Bedi, Boundia Alexandre Thiombiano
BACKGROUND: Retention in care and adherence to antiretroviral therapy (ART) among people living with human immunodeficiency virus (PLHIV) is a critical challenge in many African countries including Burkina Faso. Delivering text messaging (short message service, SMS) interventions through mobile phones may help facilitate health service delivery and improve patient health. Despite this potential, no evaluations have been delivered for national scale settings to demonstrate the impact of mobile health (mHealth) for PLHIV...
August 17, 2016: JMIR Research Protocols
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