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https://www.readbyqxmd.com/read/29236043/stress-induced-endocrine-and-immune-dysfunctions-in-caregivers-of-people-with-eating-disorders
#1
Ángel Romero-Martínez, Luis Moya-Albiol
Caregivers have to cope repeatedly with acute stressors in their daily lives, and this is associated with disturbances in the hypothalamic-pituitary-adrenal (HPA) axis and the immune system. Such disturbances could contribute to the development of health problems in informal caregivers of people with chronic illnesses, such as eating disorders (EDs). The main objective of this study was to examine endocrine (salivary cortisol levels (Csal)), immune (immunoglobulin-A (IgA)), and psychological (anxiety, mood, and anger feelings) responses to an acute psychological stressor in a sample of informal caregivers of individuals with EDs compared to a sample of non-caregivers...
December 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29235984/deaths-leading-causes-for-2015
#2
Melonie Heron
Objectives-This report presents final 2015 data on the 10 leading causes of death in the United States by age, sex, race, and Hispanic origin. Leading causes of infant, neonatal, and postneonatal death are also presented. This report supplements "Deaths: Final Data for 2015," the National Center for Health Statistics' annual report of final mortality statistics. Methods-Data in this report are based on information from all death certificates filed in the 50 states and the District of Columbia in 2015. Causes of death classified by the International Classification of Diseases, Tenth Revision (ICD-10) are ranked according to the number of deaths assigned to rankable causes...
November 2017: National Vital Statistics Reports
https://www.readbyqxmd.com/read/29235366/assessing-the-public-health-impact-of-using-poison-center-data-for-public-health-surveillance
#3
Alice Wang, Royal Law, Rebecca Lyons, Ekta Choudhary, Amy Wolkin, Joshua Schier
CONTEXT: The National Poison Data System (NPDS) is a database and surveillance system for US poison centers (PCs) call data. The Centers for Disease Control and Prevention (CDC) and American Association of Poison Control Centers (AAPCC) use NPDS to identify incidents of potential public health significance. State health departments are notified by CDC of incidents identified by NPDS to be of potential public health significance. Our objective was to describe the public health impact of CDC's notifications and the use of NPDS data for surveillance...
December 13, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/29235169/chile-crece-contigo-implementation-results-and-scaling-up-lessons
#4
A Torres, F Lopez Boo, V Parra, C Vazquez, S Segura-Pérez, Z Cetin, R Pérez-Escamilla
BACKGROUND: Chile Crece Contigo (ChCC) is defined as a comprehensive, intersectoral, and multicomponent policy that aims to help all children reach their full potential for development, regardless of their socio-economic status. METHODS: This case study was developed on the basis of grey literature review and key informants' interviews. RESULTS: ChCC behaves as a complex adaptive system that combines universal and targeted benefits for the more vulnerable starting since gestation and until the children are 4 years old...
January 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29234080/genomic-diversity-and-macroecology-of-the-crop-wild-relatives-of-domesticated-pea
#5
Petr Smýkal, Iveta Hradilová, Oldřich Trněný, Jan Brus, Abhishek Rathore, Michael Bariotakis, Roma Rani Das, Debjyoti Bhattacharyya, Christopher Richards, Clarice J Coyne, Stergios Pirintsos
There is growing interest in the conservation and utilization of crop wild relatives (CWR) in international food security policy and research. Legumes play an important role in human health, sustainable food production, global food security, and the resilience of current agricultural systems. Pea belongs to the ancient set of cultivated plants of the Near East domestication center and remains an important crop today. Based on genome-wide analysis, P. fulvum was identified as a well-supported species, while the diversity of wild P...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29233930/critical-research-gaps-and-recommendations-to-inform-research-prioritisation-for-more-effective-prevention-and-improved-outcomes-in-colorectal-cancer
#6
REVIEW
Mark Lawler, Deborah Alsina, Richard A Adams, Annie S Anderson, Gina Brown, Nicola S Fearnhead, Stephen W Fenwick, Stephen P Halloran, Daniel Hochhauser, Mark A Hull, Viktor H Koelzer, Angus G K McNair, Kevin J Monahan, Inke Näthke, Christine Norton, Marco R Novelli, Robert J C Steele, Anne L Thomas, Lisa M Wilde, Richard H Wilson, Ian Tomlinson
OBJECTIVE: Colorectal cancer (CRC) leads to significant morbidity/mortality worldwide. Defining critical research gaps (RG), their prioritisation and resolution, could improve patient outcomes. DESIGN: RG analysis was conducted by a multidisciplinary panel of patients, clinicians and researchers (n=71). Eight working groups (WG) were constituted: discovery science; risk; prevention; early diagnosis and screening; pathology; curative treatment; stage IV disease; and living with and beyond CRC...
January 2018: Gut
https://www.readbyqxmd.com/read/29233853/variation-in-pediatric-procedural-sedations-across-children-s-hospital-emergency-departments
#7
Andrew F Miller, Michael C Monuteaux, Florence T Bourgeois, Eric W Fleegler
OBJECTIVES: Describe the trends in pediatric sedation use over time and determine variation in use of procedural sedation across children's hospital emergency departments (EDs). METHODS: We analyzed ED data from 35 hospitals within the Pediatric Health Information System for patients <19 years old who received sedation medications and were discharged from 2009 to 2014. Patients with chronic comorbidities or undergoing intubation were excluded. We determined frequency and trends in use of sedation and compared these between EDs...
December 12, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/29233722/county-level-contextual-factors-associated-with-diabetes-incidence-in-the-united-states
#8
Solveig A Cunningham, Shivani A Patel, Gloria L Beckles, Linda S Geiss, Neil Mehta, Hui Xie, Giuseppina Imperatore
PURPOSE: Health and administrative systems are facing spatial clustering in chronic diseases such as diabetes. This study explores how geographic distribution of diabetes in the United States is associated with socioeconomic and built environment characteristics and health-relevant policies. METHODS: We compiled nationally representative county-level data from multiple data sources. We standardized characteristics to a mean = 0 and a SD = 1 and modeled county-level age-adjusted diagnosed diabetes incidence in 2013 using 2-level hierarchical linear regression...
November 23, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29233402/the-use-of-twitter-to-facilitate-engagement-and-reflection-in-a-constructionist-learning-environment
#9
Shane P Desselle
OBJECTIVES: Determine students' self-reported use of Twitter in a health systems course and gauge their perceptions of its value and utility for self-guided supplementation of course material, and evaluate the quality of students' reflections from information they found on Twitter. METHODS: Students in a health systems course create a Twitter account to remain abreast of current developments in pharmacy and health systems. They were afforded the autonomy to follow organizations/individuals they chose and write reflective mini-papers on selected tweets from their Twitter feed prior to each course session...
March 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29233386/a-national-survey-on-the-current-status-of-informatics-residency-education-in-pharmacy
#10
Anthony Blash, Connie L Saltsman, Condit Steil
BACKGROUND AND PURPOSE: Upon completion of their post-graduate training, pharmacy informatics residents need to be prepared to interact with clinical and technology experts in the new healthcare environment. This study describes pharmacy informatics residency programs within the United States. EDUCATIONAL ACTIVITY AND SETTING: Preliminary information for all pharmacy informatics residency programs was accessed from program webpages. An email was sent out to programs asking them to respond to a six-item questionnaire...
November 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29233152/hyperuricemia-and-metabolic-syndrome-in-type-2-diabetes-mellitus-patients-at-hawassa-university-comprehensive-specialized-hospital-south-west-ethiopia
#11
Shiferaw Bekele Woyesa, Agete Tadewose Hirigo, Temesgen Bizuayehu Wube
BACKGROUND: Metabolic syndrome is a cluster of the most dangerous heart attack risk factors such as diabetes and prediabetes, abdominal obesity, high cholesterol and high blood pressure. Hyperuricemia is a condition in which the serum uric acid concentration is greater than 5.5 mg per deciliter for child and greater than 7.2 and 6.0 mg per deciliters for male and female adults respectively. METHODS: A cross-sectional study was conducted to determine the magnitude of hyperuricemia and associated factors among type 2 diabetes mellitus patients at Hawassa Comprehensive Specialized Hospital (HCSH) from February 28 to May 30 /2017...
December 12, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/29233097/individualized-support-for-informal-caregivers-of-people-with-dementia-effectiveness-of-the-german-adaptation-of-reach-ii
#12
Martin Berwig, Stephanie Heinrich, Jenny Spahlholz, Nina Hallensleben, Elmar Brähler, Hermann-Josef Gertz
BACKGROUND: Individualized, outreach and structured multicomponent interventions are a promising intervention approach to relieve the burden of informal caregivers of people with dementia. In this study, we adapted and evaluated a multicomponent intervention (Resources for Enhancing Alzheimer's Caregiver Health II, REACH II), which was developed in the USA, to the German health-care system. Therefore the project is called the German adaptation of REACH II (in German: Deutsche Adaptation der REACH II, DE-REACH)...
December 12, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29232834/individual-data-linkage-of-survey-data-with-claims-data-in-germany-an-overview-based-on-a-cohort-study
#13
REVIEW
Stefanie March
Research based on health insurance data has a long tradition in Germany. By contrast, data linkage of survey data with such claims data is a relatively new field of research with high potential. Data linkage opens up new opportunities for analyses in the field of health services research and public health. Germany has comprehensive rules and regulations of data protection that have to be followed. Therefore, a written informed consent is needed for individual data linkage. Additionally, the health system is characterized by heterogeneity of health insurance...
December 9, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29232471/cytoreductive-surgery-for-ovarian-cancer-quality-assessment
#14
A H Brand, P A DiSilvestro, J Sehouli, J S Berek
Surgery is the cornerstone of treatment of ovarian cancer. Given the importance of achieving no or minimal macroscopic residual disease at primary surgery, performing an assessment of the quality of ovarian cancer surgery is crucial. Assessing the quality of care and surgical outcome allows us to establish baseline information, set standards of care and clear priorities, enable benchmarking against peers, and sustain quality improvement. We know that suboptimal care exists and variation in outcomes results...
November 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29232466/real-world-evidence-in-the-treatment-of-ovarian-cancer
#15
E A Eisenhauer
Introduction: 'Real-world evidence (RWE)' refers to information on the utilization and outcome of new therapies and technologies in clinical practice. RWE may include single institution cohort studies, population-based health services studies, or (inter)national data on survival and mortality. This paper reviews RWE on the impact of treatment in ovarian cancer. Materials and methods: A literature review of publications addressing population level survival outcomes of new surgical and systemic treatment interventions in ovarian cancer was undertaken...
November 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29231837/the-primary-health-care-system-in-china
#16
REVIEW
Xi Li, Jiapeng Lu, Shuang Hu, K K Cheng, Jan De Maeseneer, Qingyue Meng, Elias Mossialos, Dong Roman Xu, Winnie Yip, Hongzhao Zhang, Harlan M Krumholz, Lixin Jiang, Shengshou Hu
China has made remarkable progress in strengthening its primary health-care system. Nevertheless, the system still faces challenges in structural characteristics, incentives and policies, and quality of care, all of which diminish its preparedness to care for a fifth of the world's population, which is ageing and which has a growing prevalence of chronic non-communicable disease. These challenges include inadequate education and qualifications of its workforce, ageing and turnover of village doctors, fragmented health information technology systems, a paucity of digital data on everyday clinical practice, financial subsidies and incentives that do not encourage cost savings and good performance, insurance policies that hamper the efficiency of care delivery, an insufficient quality measurement and improvement system, and poor performance in the control of risk factors (such as hypertension and diabetes)...
December 9, 2017: Lancet
https://www.readbyqxmd.com/read/29230918/poor-continuity-of-care-for-tb-diagnosis-and-treatment-in-zambian-prisons-a-situation-analysis
#17
S Hatwiinda, S M Topp, M Siyambango, J B Harris, K R Maggard, C Chileshe, N Kapata, S E Reid, G Henostroza
OBJECTIVES: Prisons act as infectious disease reservoirs. We aimed to explore the challenges of TB control and continuity of care in prisons in Zambia. METHODS: We evaluated treatment outcomes for a cohort of inmates diagnosed with TB during a TB REACH funded screening program initiated by the Zambia Prisons Service and the Centre for Infectious Disease Research in Zambia. RESULTS: Between October 2010 and September 2011, 6,282 inmates from six prisons were screened for TB, of whom 374 (6...
December 12, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29230912/factors-associated-with-the-delay-of-diagnosis-of-leprosy-in-northeastern-colombia-a-quantitative-analysis
#18
Libardo Gómez, Alberto Rivera, Yesenia Vidal, Jorge Bilbao, Christa Kasang, Sandra Parisi, Eva-Maria Schwienhorst-Stich, Karl Philipp Puchner
OBJECTIVES: To determine the average time in months between the beginning of symptoms and the diagnostic confirmation of leprosy by the health system, and to investigate factors associated with diagnostic delay. METHODS: 249 patients older than 15 years diagnosed with leprosy between 2011 and 2015, in 20 endemic municipalities of northeastern Colombia, provided informed consent and were interviewed face to face. Clinical histories from health centers or hospitals where study participants were treated for leprosy were also reviewed...
December 12, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29230310/applying-systems-thinking-to-task-shifting-for-mental-health-using-lay-providers-a-review-of-the-evidence
#19
REVIEW
D Javadi, I Feldhaus, A Mancuso, A Ghaffar
Objective: This paper seeks to review the available evidence to determine whether a systems approach is employed in the implementation and evaluation of task shifting for mental health using lay providers in low- and middle-income countries, and to highlight system-wide effects of task-shifting strategies in order to better inform efforts to strength community mental health systems. Methods: Pubmed, CINAHL, and Cochrane Library databases were searched. Articles were screened by two independent reviewers with a third reviewer resolving discrepancies...
2017: Global Mental Health
https://www.readbyqxmd.com/read/29229610/follow-up-imaging-after-nephrectomy-for-cancer-in-canada-urologists-compliance-with-guidelines-an-observational-study
#20
Alice Dragomir, Armen Aprikian, Anil Kapoor, Antonio Finelli, Frédéric Pouliot, Ricardo Rendon, Peter C Black, Ronald Moore, Rodney H Breau, Jun Kawakami, Darrell Drachenberg, Jean-Baptiste Lattouf, Simon Tanguay
BACKGROUND: Surgical tumour removal remains the preferred treatment for most patients with renal cell carcinoma, and many medical associations have proposed guidelines for the optimal surveillance of patients following surgery. This study evaluated the adherence of Canadian urologists to the follow-up guidelines proposed by the Canadian Urological Association (CUA) in 2009. METHODS: The study cohort was identified from the Canadian Kidney Cancer Information System, a prospectively populated database from 15 academic institutions in 6 Canadian provinces: British Colombia, Alberta, Manitoba, Ontario, Quebec and Nova Scotia...
December 11, 2017: CMAJ Open
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