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https://www.readbyqxmd.com/read/29328034/characteristics-of-articular-syndrome-in-systemic-vasculitis
#1
O Syniachenko, O Khaniukov, Ye Yehudina, H Taktashov, K Gashynova
The purpose of the study - investigation the separate joint lesion in systemic vasculitis, their X-ray sonographic characteristics, the correlation of the articular syndrome severity with extra-articular manifestations of the diseases, as well as aspects of the arthritis pathogenesis in this category of patients. The study included 525 patients in the ratio of the examined with Henoch-Schonlen purpura, microscopic polyangiitis, cryoglobulinemic vasculitis, polyarteritis nodosa, Takayasu's arteritis, Wegener's granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis Churg-Strauss as a 7:4:3:1:1:1:1...
December 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29321430/new-onset-takayasu-s-arteritis-as-acute-myocardial-infarction
#2
Yusuke Ishiyama, Kazuo Eguchi, Katsuaki Yokota, Tomokazu Ikemoto, Kazuomi Kario
We herein report the case of a 25-year-old Japanese woman with left-main-trunk acute myocardial infarction (LMT-AMI). She had cardiogenic shock, so emergency percutaneous intervention was performed. Intravascular ultrasound of LMT-AMI showed that the three-layered structure of the intima, tunica media, and adventitia was not clearly visible, and the vessel was concentrically thickened; unstable plaque and calcification were not seen. AMI is rarely seen in young women, but Takayasu's arteritis is one major cause...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29320845/subcutaneous-administration-of-tocilizumab-is-effective-in-myointimal-hyperplasia-remodelling-in-refractory-takayasu-arteritis
#3
A Lo Gullo, G Mandraffino, C O Aragona, A Molica Colella, A Saitta, E Imbalzano
Takayasu arteritis (TA) is a chronic inflammatory disease of unknown origin that involves large and mediumsized arteries, primarily the aorta and its major branches. TA is a therapeutic challenge because corticosteroids and conventional immunosuppressive agents are not always effective or safe. Interleukin 6 (IL-6) has emerged as a key cytokine in the pathogenesis of TA and its serum levels have been shown to well correlate with disease activity. We report a 19 years old female patient with TA refractory to conventional immunosuppressive agents, successfully treated with subcutaneous tocilizumab, a humanized monoclonal antibody against IL-6 receptor, in which ultrasonography (US) was used as imaging tool to follow up the patient...
December 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/29313811/imaging-modalities-for-the-diagnosis-and-disease-activity-assessment-of-takayasu-s-arteritis-a-systematic-review-and-meta-analysis
#4
REVIEW
Lillian Barra, Tahir Kanji, Jacqueline Malette, Christian Pagnoux, Can Vasc
BACKGROUND: Early diagnosis of Takayasu's Arteritis (TAK) and detection of disease activity may reduce the risk of vascular complications. The objective of this study was to determine the effectiveness of imaging modalities for the management of TAK. METHODS: MEDLINE and EMBASE were searched for studies of patients undergoing various imaging modalities for TAK diagnosis or to assess disease activity. We excluded case reports, reviews and case series with <10 patients...
December 4, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29313449/treatment-with-corticosteroid-and-or-immunosuppressive-agents-before-surgery-can-effectively-improve-the-surgical-outcome-in-patients-with-takayasu-s-arteritis
#5
Tie Zheng, Shuai Zhu, Jia-Fu Ou, Wei-Gang Fang, Zhi-Yu Qiao, Rui-Dong Qi, Li Chen, Lei Chen, Cheng-Nan Li, Li-Li Pan, Qing Zhu, Dong Chen, Xue-Jun Sun, Jun-Ming Zhu
OBJECTIVE: To analyze the clinical outcome of corticosteroid and/or immunosuppressive treatment preoperatively in patients with Takayasu's arteritis. PATIENTS AND METHODS: Forty-six patients with Takayasu's arteritis who received cardiovascular surgery between January 2010 and December 2015 in Beijing Anzhen Hospital were enrolled in this study. Their clinical characteristics, preoperative drug therapy, surgical treatment, and pathological examination results were retrospectively analyzed for the effect of drugs on outcome of the surgery...
January 9, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29311677/publisher-correction-anti-inflammatory-and-anti-fibrotic-effects-of-intravenous-adipose-derived-stem-cell-transplantation-in-a-mouse-model-of-bleomycin-induced-interstitial-pneumonia
#6
Takuya Kotani, Ryota Masutani, Takayasu Suzuka, Katsuhiro Oda, Shigeki Makino, Masaaki Ii
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29305362/axillary-artery-aneurysm-combined-with-brachial-plexus-palsy-due-to-takayasu-arteritis
#7
Denise Kim, Graham Roche-Nagle
We report the case of a young female patient who presented with a right axillary artery aneurysm with neurological symptoms due to Takayasuarteritis (TA). Decompression of the aneurysm and arterial repair with an interposition vein bypass resulted in a full recovery. The case emphasises that peripheral aneurysms can occur due to TA and that there may be neurological complications.
January 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29299706/18f-fdg-pet-ct-an-accurate-method-to-assess-the-activity-of-takayasu-s-arteritis
#8
Xiaojie Zhang, Jun Zhou, Ying Sun, Hongcheng Shi, Zongfei Ji, Lindi Jiang
The objective of the study is to investigate the value of 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) for assessment of the activity of Takayasu's arteritis (TA) and the correlation between acute-phase reactive proteins (ARPs) and standard uptake value (SUV). Analyses of the clinical characteristics and 42 18F-FDG-PET/CT scans in 39 TA patients were undertaken. The degree of FDG uptake in the blood vessel walls was assessed quantitatively by SUV. TA activity was analyzed by physician global assessment (PGA)...
January 3, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29283918/clinical-utility-of-intraoperative-motor-evoked-potential-monitoring-to-prevent-postoperative-spinal-cord-injury-in-thoracic-and-thoracoabdominal-aneurysm-repair-an-audit-of-the-japanese-association-of-spinal-cord-protection-in-aortic-surgery-database
#9
Kenji Yoshitani, Kenichi Masui, Masahiko Kawaguchi, Mikito Kawamata, Manabu Kakinohana, Shinya Kato, Kyoko Hasuwa, Michiaki Yamakage, Yusuke Yoshikawa, Kimitoshi Nishiwaki, Tadashi Aoyama, Yoshimi Inagaki, Kazumasa Yamasaki, Mishiya Matsumoto, Kazuyoshi Ishida, Atsuo Yamashita, Katsuhiro Seo, Shinichi Kakumoto, Hironobu Hayashi, Yuu Tanaka, Satoshi Tanaka, Takashi Ishida, Hiroyuki Uchino, Takayasu Kakinuma, Yoshitsugu Yamada, Yoshiteru Mori, Shunsuke Izumi, Kunihiro Nishimura, Michikazu Nakai, Yoshihiko Ohnishi
BACKGROUND: Spinal cord ischemic injury is the most devastating sequela of descending and thoracoabdominal aortic surgery. Motor-evoked potentials (MEPs) have been used to intraoperatively assess motor tract function, but it remains unclear whether MEP monitoring can decrease the incidence of postoperative motor deficits. Therefore, we reviewed multicenter medical records of patients who had undergone descending and thoracoabdominal aortic repair (both open surgery and endovascular repair) to assess the association of MEP monitoring with postoperative motor deficits...
December 26, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29279466/prolonged-dry-cough-without-pulmonary-changes-on-radiological-imaging
#10
Takeshi Kondo, Yoshiyuki Ohira, Takanori Uehara, Kazutaka Noda, Tomoko Tsukamoto, Masatomi Ikusaka
A 16-year-old boy who was a non-smoker presented with a prolonged severe dry cough and malaise of 3 months in duration. Despite an increase in the patient's inflammatory marker levels, no respiratory lesions were radiologically or serologically detected. We suspected that the cough reflex pathway had been stimulated by large vessel vasculitis (a non-respiratory inflammatory condition) and diagnosed the patient with Takayasu arteritis. While inflammation of either the ascending pharyngeal or pulmonary artery have been reported to cause cough in patients with large vessel vasculitis, the present case shows that intense inflammation of the aortic arch and the starting portion of its main branches may stimulate a vagus nerve branch as a novel mechanism causing cough...
December 27, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29274449/proton-mrs-detection-of-high-lipid-levels-and-low-adc-is-characteristics-of-germinoma
#11
Fumiyuki Yamasaki, Yasuyuki Kinoshita, Takeshi Takayasu, Satoshi Usui, Manish Kolakshyapati, Motoki Takano, Sayuru Tsuyuguchi, Vishwa Jeet Amatya, Yuji Akiyama, Yukio Takeshima, Kazuhiko Sugiyama, Kaoru Kurisu
BACKGROUND: The differentiation of germinoma from other tumors by conventional MRI can be very difficult. The purpose of our study was to determine if proton magnetic resonance spectroscopy and diffusion-weighted imaging could give additional information for definitive diagnosis of germinoma. MATERIALS AND METHODS: Our institutional review board approved this retrospective study. We reviewed the images of 26 patients with histologically confirmed germinoma who were treated in our institution between 2003 and 2016...
December 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29273399/behavioral-defects-in-a-dctn1g71a-transgenic-mouse-model-of-perry-syndrome
#12
Takayasu Mishima, Manami Deshimaru, Takuya Watanabe, Kaori Kubota, Mariko Kinoshita-Kawada, Junichi Yuasa-Kawada, Kotaro Takasaki, Yoshinari Uehara, Shozo Jinno, Katsunori Iwasaki, Yoshio Tsuboi
Perry syndrome is a rare neurodegenerative disease characterized by parkinsonism, depression/apathy, weight loss, and central hypoventilation. Our previously-conducted genome-wide association scan and subsequent studies identified nine mutations in DCTN1, the largest protein subunit of the dynactin complex, in patients with Perry syndrome. These included G71A in the microtubule-binding cytoskeleton-associated protein Gly-rich domain of p150Glued. The dynactin complex is essential for function of the microtubule-based cytoplasmic retrograde motor dynein...
December 19, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29249430/prevalence-of-takayasu-arteritis-in-young-women-with-acute-ischemic-heart-disease
#13
Giulio Cavalli, Alessandro Tomelleri, Davide Di Napoli, Elena Baldissera, Lorenzo Dagna
OBJECTIVES: Takayasu arteritis (TA), a systemic vasculitis typically occurring in female patients aged ≤40, can affect coronary arteries and cause ischemic heart disease (IHD). In this study, we investigated the prevalence of TA in young women presenting with IHD in the Emergency Department. METHODS: We evaluated hospital records of 158,860 consecutive female patients aged <40, who accessed the Emergency Department of our institution over 8 consecutive years (2007-2015)...
February 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29245165/video-capsule-endoscopy-diagnosis-of-takayasu-s-arteritis
#14
Carolina Olano, Henry Cohen
No abstract text is available yet for this article.
December 15, 2017: Endoscopy
https://www.readbyqxmd.com/read/29242069/large-vessel-vasculitis-in-human-immunodeficiency-virus-infected-patients
#15
Yasmina Ferfar, Léa Savey, Cloé Comarmond, Nirvana Sadaghianloo, Marlène Garrido, Fanny Domont, Marc Antoine Valantin, Valérie Pourcher-Martinez, Philippe Cluzel, Pierre Fouret, Laurent Chiche, Julien Gaudric, Fabien Koskas, Patrice Cacoub, David Saadoun
OBJECTIVE: The objective of this study was to describe large-vessel vasculitis (LVV) in patients with human immunodeficiency virus (HIV) infection. It is a retrospective single-center study conducted between 2000 and 2015 through a university hospital of 11 HIV-infected patients with LVV. METHODS: The characteristics and outcome of 11 HIV-infected patients with LVV (7 patients fulfilled international criteria for Takayasu arteritis, 5 patients had histologic findings of vasculitis, and 5 patients had imaging features of aortitis) were analyzed and compared with those of 82 patients with LVV but without HIV infection...
December 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29238882/the-presentation-and-management-of-hypertension-in-a-large-cohort-of-takayasu-arteritis
#16
Yu Qi, Lirui Yang, Huimin Zhang, Erpeng Liang, Lei Song, Jun Cai, Xiongjing Jiang, Yubao Zou, Haiyan Qian, Haiying Wu, Xianliang Zhou, Rutai Hui, Deyu Zheng
The objective of this study was to explore the presentation and management of hypertension secondary to Takayasu arteritis (TA) in a large cohort, single center in China. We retrospectively analyzed 381 TA patients with hypertension hospitalized in Fuwai hospital between Jan. 2004 and Feb. 2014. Diagnosis of hypertension was according to clinic blood pressure or the central blood pressure measured during angiography. Renal artery stenosis was the most common cause (264, 69.3%), followed by the thoracic descending aorta stenosis (98, 25...
December 14, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29238022/-coexistence-of-takayasu-s-arteritis-and-inflammatory-colitis-detected-by-fluorodeoxyglucose-positron-emission-tomography
#17
Yoshiro Horai, Shota Kurushima, Takashi Igawa, Kunihiro Ichinose, Hideki Nakamura, Atsushi Kawakami
  A woman in her thirties was diagnosed as Takayasu's arteritis (TAK) by dilatation, wall thickness of her abdominal aorta in contrast-enhanced computed tomography. Although she didn't have any subjective bowel symptoms, fluorodeoxyglucose (FDG)-positron emission tomography (PET) also revealed uptake of FDG in descending colon, and colonoscopy revealed aphthous colitis. After the start of steroid therapy, both arteritis and colitis were improved. FDG-PET can detect TAK and inflammatory bowel diseases at an early stage...
2017: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
https://www.readbyqxmd.com/read/29234289/the-role-of-perivascular-adipose-tissue-in-non-atherosclerotic-vascular-disease
#18
REVIEW
Tetsuo Horimatsu, Ha Won Kim, Neal L Weintraub
Perivascular adipose tissue (PVAT) surrounds most large blood vessels and plays an important role in vascular homeostasis. PVAT releases various chemokines and adipocytokines, functioning in an endocrine and paracrine manner to regulate vascular signaling and inflammation. Mounting evidence suggests that PVAT plays an important role in atherosclerosis and hypertension; however, the role of PVAT in non-atherosclerotic vascular diseases, including neointimal formation, aortic aneurysm, arterial stiffness and vasculitis, has received far less attention...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29233197/takayasu-arteritis-in-paediatrics
#19
Marisa Di Santo, Erica V Stelmaszewski, Alejandra Villa
Takayasu arteritis is an idiopathic chronic granulomatous panarteritis predominantly affecting the aorta and its main branches. Although idiopathic, genetic contribution to disease susceptibility is being increasingly recognised. Rare in children, Takayasu arteritis is a worldwide disease with significant morbidity and mortality. Its diagnosis is a challenge and requires awareness of the condition as clinical features at presentation are non-specific and assessing disease activity is difficult. In the inflammatory stage, treatment is essential to prevent the insidious course and vascular damage: stenotic, occlusive lesions, aneurysms, and aortic regurgitation...
December 13, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29229107/clinical-characterization-of-52-patients-with-immunoglobulin-g4-related-disease-in-a-single-tertiary-center-in-japan-special-reference-to-lung-disease-in-thoracic-high-resolution-computed-tomography
#20
Takeshi Saraya, Kosuke Ohkuma, Masachika Fujiwara, Chika Miyaoka, Shoko Wada, Takayasu Watanabe, Sunao Mikura, Manami Inoue, Miku Oda, Mitsuru Sada, Yukari Ogawa, Kojiro Honda, Masaki Tamura, Takuma Yokoyama, Daisuke Kurai, Haruyuki Ishii, Hajime Takizawa
BACKGROUND: Immunoglobulin G4-related disease (IgG4-RD) is a rare multi-organ disorder. Physicians rarely encounter patients with IgG4-RD and its range of symptoms. METHODS: To elucidate the clinical characterization of IgG4-RD, along with the clinical significance of lung involvement, we retrospectively reviewed the medical records of patients who satisfied the comprehensive diagnostic criteria for IgG4-RD. RESULTS: We identified 52 patients with IgG4-RD...
November 2017: Respiratory Medicine
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