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https://www.readbyqxmd.com/read/29661274/granular-cell-tumor-experience-at-a-comprehensive-cancer-center
#1
Ambria S Moten, Sujana Movva, Margaret von Mehren, Hong Wu, Nestor F Esnaola, Sanjay S Reddy, Jeffrey M Farma
BACKGROUND: Granular cell tumors (GCTs) are rare lesions occurring almost anywhere in the body. Multiple case reports have been published. However, there are very few large-scale studies regarding GCT. The aim of this study was to define characteristics, treatment patterns and outcomes of patients with GCT. METHODS: An institutional review board-approved retrospective chart review was performed. Descriptive statistics, chi-square analyses, and Kaplan-Meier survival estimates were produced...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29655650/surgical-treatment-of-lisfranc-injury-with-plantar-plate-approach
#2
Deepal Dalal, Christian Curry, Ryan Carter, Colin Zdenek, Nicholas W Todd, Shannon M Rush, Richard Jensen
Midfoot injuries are the second most common athletic foot injury documented in the published data. High-energy Lisfranc dislocations are commonly seen secondary to traumatic etiologies and disrupt the strong midfoot ligaments supporting the arch. These injuries require immediate surgical intervention to prevent serious complications such as compartment syndrome and amputation. The present case series reports a new Lapidus plate system used in 3 patients who underwent arthrodesis procedures for Lisfranc joint dislocation...
April 11, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29649058/asymptomatic-deep-vein-thrombosis-during-free-flap-concerns-in-free-flap-surgery
#3
Jae-A Jung, Bo Young Park, So-Ra Kang, Min Ji Kim
BACKGROUND: Venous insufficiency is the most frequent cause of failure in free flap reconstruction of the lower extremity. When deep vein thrombosis (DVT) is detected during preoperative assessment of the lower extremity, decisions regarding treatment plans become difficult, and no relevant guidelines regarding surgery and preoperative treatment of patients with DVT who need a free flap transfer are currently available. METHODS: In order to find a relevant guideline in decision-making regarding surgery and preoperative treatment of patients with DVT who require free flap reconstruction, a systematic literature review was conducted searching MEDLINE, PubMed Central, Cochrane, and Embase databases for articles published between 1996 and 2015...
March 30, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29623629/impact-of-fluid-choice-in-systemic-inflammatory-response-syndrome-patients-on-hospital-cost-savings
#4
Suzanne Laplante, Dilip U Makhija, Sibyl H Munson, Victor S Khangulov, Fred W Peyerl, Scott M Paluszkiewicz, Aditi J Ravindranath, Carol R Schermer
BACKGROUND: There is growing evidence of the benefits of intravenous fluid therapy with balanced crystalloids over 0.9% 'normal' saline. This analysis evaluated the economic impact of increasing usage of a calcium-free balanced crystalloid solution (BAL) in patients with systemic inflammatory response syndrome (SIRS) on an annual hospital budget. METHODS: An Excel® -based economic model was developed to estimate costs associated with increased BAL usage (i.e., use in a greater proportion of patients), from the US hospital perspective, over a 5-year time horizon...
September 4, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29623209/concurrent-primary-hyperparathyroidism-and-pheochromocytoma-in-a-chinese-lady-with-neurofibromatosis-type-1
#5
Cheuk-Lik Wong, Chun-Kit Fok, Vicki Ho-Kee Tam
We report a case of elderly Chinese lady with neurofibromatosis type-1 presenting with longstanding palpitation, paroxysmal hypertension and osteoporosis. Biochemical testing showed mild hypercalcaemia with non-suppressed parathyroid hormone level suggestive of primary hyperparathyroidism, and mildly elevated urinary fractionated normetanephrine and plasma-free normetanephrine pointing to a catecholamine-secreting pheochromocytoma/paraganglioma. Further scintigraphic investigation revealed evidence of a solitary parathyroid adenoma causing primary hyperparathyroidism and a left pheochromocytoma...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29620792/risk-reducing-mastectomy-for-the-prevention-of-primary-breast-cancer
#6
REVIEW
Nora E Carbine, Liz Lostumbo, Judi Wallace, Henry Ko
BACKGROUND: Recent progress in understanding the genetic basis of breast cancer and widely publicized reports of celebrities undergoing risk-reducing mastectomy (RRM) have increased interest in RRM as a method of preventing breast cancer. This is an update of a Cochrane Review first published in 2004 and previously updated in 2006 and 2010. OBJECTIVES: (i) To determine whether risk-reducing mastectomy reduces death rates from any cause in women who have never had breast cancer and in women who have a history of breast cancer in one breast, and (ii) to examine the effect of risk-reducing mastectomy on other endpoints, including breast cancer incidence, breast cancer mortality, disease-free survival, physical morbidity, and psychosocial outcomes...
April 5, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29619573/-idiopathic-systemic-capillary-leak-syndrome-clarkson-disease-a-rare-cause-of-recurrent-life-threatening-edema
#7
REVIEW
S Dasdelen, S-O Grebe
This case report describes the episodic occurrence of severe generalized edema in a young female patient, who developed hypertension with a massive hemoconcentration (hematocrit >0.5, hemoglobin >20g/dl) and hypoalbuminemia during the course of these acute disease phases. After the first two disease exacerbations were overcome, there was a complete regression of symptoms. After a long symptom-free interval, a new exacerbation occurred as a result of which critical organ ischemia occurred due to the severe hypotension and massive edema...
April 4, 2018: Der Internist
https://www.readbyqxmd.com/read/29605778/cirrhosis-following-single-anastomosis-duodeno-ileal-switch-a-case-report
#8
Vincent Kirkpatrick, Rena C Moon, Andre F Teixeira, Muhammad A Jawad
INTRODUCTION: Single anastomosis duodeno-ileal switch (SADI-S) involves a single, loop duodeno-ileal anastomosis with omission of the traditional Roux-en-Y distal ileo-ileal anastomosis. Not much has been published on the complications of SADI-S. PRESENTATION OF CASE: The patient is a 40 year-old male who underwent robot-assisted SADI-S three years prior. At the time of surgery, his body mass index (BMI) was 69 kg/m2 . His BMI was 31 kg/m2 at the time of presentation...
March 17, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29603477/challenges-and-limitations-in-the-diagnosis-of-atrio-esophageal-fistula
#9
Francis J Ha, Hui-Chen Han, Prashanthan Sanders, Andrew W Teh, David O'Donnell, Omar Farouque, Han S Lim
INTRODUCTION: Atrio-esophageal fistula (AEF) is a dire complication of atrial fibrillation ablation. The diagnostic yield of computed tomography (CT) chest, the role and timing of repeat testing, and the value of other investigations in the diagnosis of AEF is uncertain. METHODS: We systematically reviewed published AEF cases to evaluate radiological, bedside and biochemical investigations for AEF (registered on PROSPERO [CRD42017077493]). RESULTS: Eighty-seven articles with 126 patients (median age, 59 years; male, 71%) were included in the analysis...
March 30, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29577510/successful-treatment-with-steroid-and-cyclosporine-a-in-a-patient-with-immunoglobulin-a-proliferative-glomerulonephritis-with-monoclonal-immunoglobulin-deposits
#10
Keisuke Sato, Shiho Makabe, Yuko Iwabuchi, Kaori Kojima, Masayo Sato, Hiroshi Kataoka, Takahito Moriyama, Sekiko Taneda, Ken Tsuchiya, Kosaku Nitta, Toshio Mochizuki
We report a case of glomerulonephritis with monoclonal immunoglobulin (Ig) A deposits as a form of monoclonal gammopathy of renal significance (MGRS) caused by monoclonal immunoglobulins without blood disorders in a 41-year-old woman. She developed lower leg oedema and was hospitalized because of nephrotic syndrome. Serum and urine were negative for M protein, and the free light chain κ/λ ratio was within the normal range. Renal histopathological findings included mesangial proliferation, endocapillary cell proliferation, and a double-contour appearance of the capillary walls...
March 25, 2018: Nephrology
https://www.readbyqxmd.com/read/29561434/meta-analysis-of-cdkn2a-methylation-to-find-its-role-in-prostate-cancer-development-and-progression-and-also-to-find-the-effect-of-cdkn2a-expression-on-disease-free-survival-prisma
#11
Zipei Cao, Lijuan Wei, Weizhi Zhu, Xuping Yao
BACKGROUND: Reduction of cyclin-dependent kinase inhibitor 2A (CDKN2A) (p16 and p14) expression through DNA methylation has been reported in prostate cancer (PCa). This meta-analysis was conducted to assess the difference of p16 and p14 methylation between PCa and different histological types of nonmalignant controls and the correlation of p16 or p14 methylation with clinicopathological features of PCa. METHODS: According to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement criteria, articles were searched in PubMed, Embase, EBSCO, Wanfang, and CNKI databases...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29557421/hemorrhagic-events-in-adult-celiac-disease-patients-case-report-and-review-of-the-literature
#12
Alina Dima, Ciprian Jurcut, Anca Manolache, Daniel Vasile Balaban, Alina Popp, Mariana Jinga
BACKGROUND AND AIMS: Celiac disease (CD) presents with a wide spectrum of extra-digestive symptoms, including hemorrhagic manifestations. The aim of this review was to conduct an extensive analysis of the hemorrhagic events reported in adult CD patients. METHODS: Case report and review of the literature. Pubmed (MEDLINE) database search from January 1970 onwards was performed using the medical subject headings [MeSH] terms "celiac disease" AND "blood coagulation disorders", "hemorrhage", "hematoma", "hematuria", "hemoptysis", "epistaxis", "hemosiderosis"...
March 2018: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/29548835/prevention-of-leber-congenital-amaurosis-through-preimplantation-genetic-diagnosis
#13
Sylvia R Kodsi, Sara L Bristow, Joyce E Fox, Avner Hershlag
Preimplantation genetic diagnosis can allow a family with a hereditary genetic mutation to conceive a disease-free child. We report the first published case of a child born without Leber congenital amaurosis through preimplantation genetic testing to a couple who had a son with a homozygous mutation in the GUCY2D gene.
March 13, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29538255/the-role-of-radiotherapy-in-extramammary-paget-disease-a-systematic-review
#14
L Tagliaferri, C Casà, G Macchia, A Pesce, G Garganese, B Gui, G Perotti, S Gentileschi, F Inzani, R Autorino, S Cammelli, A G Morganti, V Valentini, M A Gambacorta
OBJECTIVE/PURPOSE: Extramammary Paget disease (EMPD) is a rare neoplasm of the skin generally affecting the anogenital area. Because of the low-frequency of the disease, no specific guidelines about the treatment strategy are available. Surgery is the recommended therapy for resectable and localized disease, but several other local treatments have been reported such as radiotherapy (RT). Most articles report small retrospective studies, referring to patients treated decades ago with large heterogeneity in terms of RT dose and technique...
March 17, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29529308/cryptococcosis-in-the-koala-phascolarctos-cinereus-pathogenesis-and-treatment-in-the-context-of-two-atypical-cases
#15
Laura J Schmertmann, Kathryn Stalder, Donald Hudson, Patricia Martin, Mariano Makara, Wieland Meyer, Richard Malik, Mark B Krockenberger
Disseminated cryptococcosis caused by Cryptococcus gattii (molecular type VGI) was diagnosed in an adult free-ranging female koala (Phascolarctos cinereus). Subclinical cryptococcosis was later diagnosed in this koala's joey. In the adult koala, a pathological fracture of the tibia was associated with the bone lysis of marked focal cryptococcal osteomyelitis. Limb-sparing orthopedic intervention, in the setting of disseminated cryptococcosis, was judged to have a poor prognosis, and the adult koala was euthanized...
February 24, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29528796/effect-of-dry-needling-on-cubital-tunnel-syndrome-three-case-reports
#16
Sudarshan Anandkumar, Murugavel Manivasagam
This case series describes three patients who presented with right medial elbow pain managed unsuccessfully with conservative treatment that included medication, massage, exercise therapy, ultrasound therapy, neurodynamic mobilization, and taping. Diagnosis of cubital tunnel syndrome was based on palpatory findings, a positive elbow flexion test, and a positive Tinel's sign. Conventionally, the intervention for this entrapment has been surgical decompression, with successful outcomes. This is potentially a first-time description of the successful management of cubital tunnel syndrome with dry needling (DN) using a recently published DN grading system...
March 12, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29510969/using-google-glass-in-surgical-settings-systematic-review
#17
REVIEW
Nancy J Wei, Bryn Dougherty, Aundria Myers, Sherif M Badawy
BACKGROUND: In recent years, wearable devices have become increasingly attractive and the health care industry has been especially drawn to Google Glass because of its ability to serve as a head-mounted wearable device. The use of Google Glass in surgical settings is of particular interest due to the hands-free device potential to streamline workflow and maintain sterile conditions in an operating room environment. OBJECTIVE: The aim is to conduct a systematic evaluation of the literature on the feasibility and acceptability of using Google Glass in surgical settings and to assess the potential benefits and limitations of its application...
March 6, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29508130/head-and-neck-kaposi-sarcoma-clinicopathological-analysis-of-11-cases
#18
Abbas Agaimy, Sarina K Mueller, Thomas Harrer, Sebastian Bauer, Lester D R Thompson
Kaposi sarcoma (KS) of the head and neck area is uncommon with limited published case series. Our routine and consultation files were reviewed for histologically and immunohistochemically proven KS affecting any cutaneous or mucosal head and neck site. Ten males and one female aged 42-78 years (median, 51 years; mean, 52 years) were retrieved. Eight patients were HIV-positive and three were HIV-negative. The affected sites were skin (n = 5), oral/oropharyngeal mucosa (n = 5), and lymph nodes (n = 3) in variable combination...
March 5, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29494352/tenosynovial-giant-cell-tumors-in-children-a-similar-entity-compared-with-adults
#19
Monique J L Mastboom, Floortje G M Verspoor, Daniël Uittenbogaard, Gerard R Schaap, Paul C Jutte, H W Bart Schreuder, Michiel A J van de Sande
BACKGROUND: Tenosynovial giant cell tumor (TGCT) is a rare, benign, monoarticular entity. Many case-series in adults are described, whereas TGCT is only incidentally reported in children. Therefore, its incidence rate and natural history in children are unknown. QUESTIONS/PURPOSES: (1) How many cases have been reported of this condition, and what were their characteristics? (2) What is the standardized pediatric incidence rate for TGCT? (3) Is there a clinical difference in TGCT between children and adults? (4) What is the risk of recurrence after open resection in children compared with adults? METHODS: Data were derived from three sources: (1) a systematic review on TGCT in children, seeking sources published between 1990 and 2016, included 17 heterogeneous, small case-series; (2) the nationwide TGCT incidence study: the Dutch pediatric incidence rate was extracted from this nationwide study by including patients younger than 18 years of age...
February 8, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29491106/case-report-cea-elevation-can-be-a-marker-of-increased-inflammation-during-treatment-with-oxaliplatin
#20
Daniel Kerr, Damian Laber, Nathan Visweshwar, Michael Jaglal
Oxaliplatin is a platinum-based chemotherapy that is an integral part of several regimens for colorectal cancer. We present the case of a patient, a 58-year-old male, who had initially presented aged 56 years with rectal bleeding for several months. His serum carcinoembryonic antigen (CEA) level at the time of diagnosis was 4.6 ng/ml. His CEA level increased significantly during oxaliplatin-based chemotherapy and declined to a near normal level after completion of therapy. There was no evidence of disease during this time and he remains disease-free...
March 2018: Anticancer Research
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