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https://www.readbyqxmd.com/read/29226227/online-platform-as-a-tool-to-support-postgraduate-training-in-general-practice-a-case-report
#1
Lorena Dini, Claire Galanski, Susanne Döpfmer, Sabine Gehrke-Beck, Gudrun Bayer, Martin Boeckle, Isabel Micheel, Jasminko Novak, Christoph Heintze
Objective: Physicians in postgraduate training (PPT) in General Practice (GP) typically have very little interaction with their peers, as there is usually only one resident physician working in their respective department or GP office at a given time. Therefore, the online platform KOLEGEA, presented here, aims to support postgraduate training in general practice (PT in GP) in Germany through virtual interaction. Methodology: In 2012, the interdisciplinary research project KOLEGEA set up an online platform that any physicians in PT in GP can use for free after registration with their unitary continuous education number (Einheitliche Fortbildungsnummer, EFN)...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/29196890/malnutrition-and-sarcopenia-in-a-large-cohort-of-patients-with-systemic-sclerosis
#2
C Caimmi, P Caramaschi, A Venturini, E Bertoldo, E Vantaggiato, O Viapiana, M Ferrari, G Lippi, L Frulloni, M Rossini
Systemic sclerosis (SSc) is an autoimmune disease which may lead to malnutrition. Previous studies have defined it with different criteria. No thorough evaluations of sarcopenia in SSc are available. The aim of the present study was to assess the prevalence and the potential association of malnutrition and sarcopenia in a large cohort of SSc cases. A total of 141 SSc consecutive outpatients were enrolled. Body composition was analyzed by densitometry. Malnutrition was defined according to recently published ESPEN criteria, whereas sarcopenia was diagnosed in patients with reduced skeletal muscle index...
December 1, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29190192/suspected-zonisamide-related-anticonvulsant-hypersensitivity-syndrome-in-a-cat
#3
Audrey Collinet, Veronique Sammut
CASE DESCRIPTION A 2-year-old neutered male domestic shorthair cat was evaluated for sudden onset of cluster seizures. CLINICAL FINDINGS At an emergency clinic, the cat had hyperimmunoglobulinemia and thrombocytopenia. On referral, treatment with levetiracetam, zonisamide, and phenobarbital initially provided good control of cluster seizure activity (attributable to epilepsy of unknow origin). Two weeks later, assessments revealed that serum phenobarbital concentration was within the ideal range but serum zonisamide concentration exceeded the recommended therapeutic range...
December 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29190004/long-term-safety-and-survival-outcomes-from-the-scandinavian-breast-group-2004-1-randomized-phase-ii-trial-of-tailored-dose-dense-adjuvant-chemotherapy-for-early-breast-cancer
#4
Alexios Matikas, Sara Margolin, Mats Hellström, Hemming Johansson, Nils-Olof Bengtsson, Lena Karlsson, Per Edlund, Per Karlsson, Elisabet Lidbrink, Barbro Linderholm, Henrik Lindman, Per Malmstrom, Kenneth Villman, Theodoros Foukakis, Jonas Bergh
PURPOSE: Although adjuvant polychemotherapy improves outcomes for early breast cancer, the significant variability in terms of pharmacokinetics results in differences in efficacy and both short and long-term toxicities. Retrospective studies support the use of dose tailoring according to the hematologic nadirs. METHODS: The SBG 2004-1 trial was a randomized feasibility phase II study which assessed tailored dose-dense epirubicin and cyclophosphamide (EC) followed by docetaxel (T) (group A), the same regimen with fixed doses (group B) and the TAC regimen (group C)...
November 30, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29187473/melanoma-of-the-vagina-case-report-and-systematic-review-of-the-literature
#5
Violetta Rapi, Askin Dogan, Beate Schultheis, Franziska Hartmann, Günther A Rezniczek, Clemens B Tempfer
BACKGROUND: Primary melanoma of the vagina (PMV) is a rare entity. The prognosis of women with PMV is poor and there is no standardized therapy for this type of malignancy. We present the case of a 72-year-old woman with PMV (cT2, pN0, M0). CASE REPORT: Imaging studies showed no evidence of regional or distant metastases. Molecular analysis demonstrated wild-type B-Raf proto-oncogene, serine/threonine kinase (BRAF). Staging laparoscopy with pelvic lymphadenectomy and subsequent radiotherapy with 60 Gy delivered as pelvic teletherapy and vaginal brachytherapy was applied...
December 2017: Anticancer Research
https://www.readbyqxmd.com/read/29181180/comprehensive-treatment-of-unresectable-cardiac-angiosarcoma-a-case-report-and-review-of-literature
#6
Chao Wang, Min Shi, Chen Yang, Tao Ma, Jinling Jiang, Ying Liu, Wenqi Xi, Zhenggang Zhu, Jun Zhang
Cardiac angiosarcoma is a rare but lethal tumor that is difficult to diagnose and treat, due to its rapid local relapse and high incidence of systemic metastasis. The prognosis of cardiac angiosarcoma is dismal, with a mean life expectancy of only a few months. We herein report a case of unresectable angiosarcoma arising from the right atrium. The patient received first-line chemotherapy with weekly paclitaxel, and second-line therapy with vinorelbine and bevacizumab upon disease progression. The progression-free survival was 6 months and the overall survival was 7 months...
November 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29177806/the-long-term-survival-in-primary-retroperitoneal-mucinous-cystadenocarcinoma-a-case-report
#7
Hirotaka Tokai, Yasuhiro Nagata, Ken Taniguchi, Naomi Matsumura, Amane Kitasato, Takayuki Tokunaga, Hiroaki Takeshita, Tamotsu Kuroki, Shigeto Maeda, Masahiro Ito, Hikaru Fujioka
BACKGROUND: Primary retroperitoneal mucinous cystadenocarcinoma (PRMC) is extremely rare, and its biological behavior, pathogenesis, optimum treatments, and prognosis remain to be elucidated. We herein report a case of PRMC with an 80-month follow-up. CASE PRESENTATION: A 29-year-old woman was diagnosed with unknown retroperitoneal tumor with benign right ovarian cyst and uterine fibroids, and she underwent laparotomy. The tumor was completely resected with a subsequent histopathological diagnosis of primary retroperitoneal mucinous cystadenocarcinoma (PRMC)...
November 25, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29148237/supraclavicular-flap-repair-in-the-free-flap-era
#8
REVIEW
Jodie Trautman, Sinclair Gore, Matthew Potter, Jonathan Clark, Dylan Hyam, Ngian C Tan, Quan Ngo, Bruce Ashford
BACKGROUND: Supraclavicular flap (SCF) repair is widely reported in head and neck surgery in select patients and defects. The authors' objective is to present our series of 30 patients who underwent SCF repair for varying defects and to review the scope and outcome of SCF repair in the literature. METHODS: The authors contributed primary evidence of 30 cases of SCF repair. Our outcomes are compared with those reported in the last 5 years' literature; 33 articles published between January 2012 and January 2017 that present original clinical experience of 528 SCFs...
November 17, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29143274/clinical-features-surgical-management-and-prognostic-factors-of-secretory-meningiomas-a-single-center-case-series-of-149-patients
#9
Xiaogang Tao, Kun Wang, Jinqian Dong, Zonggang Hou, Zhen Wu, Junting Zhang, Baiyun Liu
Secretory meningioma (SM) is a rare histological subtype of the meningioma family. Few reports investigating SM have been published due to its extremely low incidence; thus, the current understanding of this disease is poor. We analyzed the incidence and clinical, radiological, pathological, and prognostic features of SM. Approximately 12,380 intracranial meningiomas were surgically resected at Beijing Tiantan Hospital between April 2008 and January 2017. All pathologically confirmed SM cases were identified...
November 15, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29128384/adverse-effects-of-single-component-measles-vaccine-in-school-children
#10
Selam Tosun, Ali Ilgın Olut, Nermin Tansug
Measles is a highly contagious viral infection potentially with serious complications and the principal method of protection from the disease is vaccination. Measles vaccination resulted in a 79% drop in measles deaths between 2000 and 2015 worldwide. There has long been a debate about the necessity and benefit-loss ratio of routine MMR vaccination due to possible AE of MMR vaccine. Especially in developed countries which are thought to be free of measles there is an increasing tendency towards hesitation for vaccination though there have been continued outbreaks of measles in countries in which measles is considered to be eliminated...
November 8, 2017: Vaccine
https://www.readbyqxmd.com/read/29116405/systematic-review-of-studies-reporting-positive-surgical-margins-after-bladder-neck-sparing-radical-prostatectomy
#11
REVIEW
Mariangela Bellangino, Clare Verrill, Tom Leslie, Richard W Bell, Freddie C Hamdy, Alastair D Lamb
PURPOSE OF REVIEW: Bladder neck preservation (BNP) during radical prostatectomy (RP) has been proposed as a method to improve early recovery of urinary continence after radical prostatectomy. However, there is concern over a possible increase in the risk of positive surgical margins and prostate cancer recurrence rate. A recent systematic review and meta-analysis reported improved early recovery and overall long-term urinary continence without compromising oncologic control. The aim of our study was to perform a critical review of the literature to assess the impact on bladder neck and base margins after bladder neck sparing radical prostatectomy...
November 7, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29115903/5-year-survival-after-splenectomy-in-a-patient-with-recurrent-cutaneous-melanoma-a-case-report
#12
Lynn De Roeck, Laura Wuyts, Benjamin Peters, Martin Ruppert
OBJECTIVE: Splenic metastases of melanoma are uncommon and generally part of a disseminated disease with a poor prognosis. In case of solitary visceral metastasis, surgical resection often remains an effective treatment. This case describes a long-term survival after splenectomy for a recurrent melanoma. METHODS: We present a 55-year-old female with a solitary splenic metastasis. Her medical history revealed a melanoma of the foot in 2007 and an in-transit metastasis in 2011...
November 8, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29111154/robot-assisted-partial-nephrectomy-5-yr-oncological-outcomes-at-a-single-european-tertiary-cancer-center
#13
Mihai Dorin Vartolomei, Deliu Victor Matei, Giuseppe Renne, Valeria Maria Tringali, Nicolae Crisan, Gennaro Musi, Francesco Alessandro Mistretta, Andrea Russo, Gabriele Cozzi, Giovani Cordima, Stefano Luzzago, Antonio Cioffi, Ettore Di Trapani, Michele Catellani, Maurizio Delor, Danilo Bottero, Ciro Imbimbo, Vincenzo Mirone, Matteo Ferro, Ottavio de Cobelli
BACKGROUND: Nowadays, there is a debate about which surgical treatment should be best for clinical T1 renal tumors. If the oncological outcomes are considered, there are many open and laparoscopic series published. As far as robotic series are concerned, only a few of them report 5-yr oncological outcomes. OBJECTIVE: The aim of this study was to analyze robot-assisted partial nephrectomy (RAPN) midterm oncological outcomes achieved in a tertiary robotic reference center...
October 27, 2017: European Urology Focus
https://www.readbyqxmd.com/read/29111096/multinodular-and-vacuolating-neuronal-tumor-of-the-cerebrum-a-rare-entity-new-case-and-review-of-the-literature
#14
Lain Hermes Gonzalez-Quarante, Fernando Ruiz-Juretschke, Emma Sola Vendrell, Oscar Lucas Gil de Sagredo Del Corral, Vijay Agarwal, Roberto Garcia-Leal
BACKGROUND: Multinodular and vacuolating neuronal tumor has been recently described and included in the World Health Organization Classification of Tumors of The Central Nervous System, even though its consideration as a true tumor is controversial. Patients with these lesions usually present with refractory seizures and inconclusive imaging findings that may be confused with other more common diagnoses such as dysembryoplastic neuroepithelial tumors or low-grade gliomas. Therefore, surgical resection is warranted to reach a pathologic diagnosis and seizure control...
October 28, 2017: Neurocirugía
https://www.readbyqxmd.com/read/29101556/laparoscopic-right-posterior-sectionectomy-lrps-surgical-techniques-and-clinical-outcomes
#15
Najaf N Siddiqi, Mahmoud Abuawwad, Mark Halls, Arab Rawashdeh, Francesco Giovinazzo, Anas Aljaiuossi, Dennis Wicherts, Mathieu D'Hondt, Mohammed Abu Hilal
BACKGROUND: Right posterior sectionectomy is one of the most technically challenging laparoscopic liver resections. Currently, there is limited published data regarding the technique and results required to better understand its safety and feasibility. AIM: To report our experience, results and techniques, highlighting a variety of tips and tricks to facilitate this resection. A video is attached for technical demonstration. METHODS: Retrospective review of prospectively maintained databases from June 2006 to June 2016...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29080993/a-surgical-solution-to-regain-bowel-continuity-following-an-extended-left-colectomy-reviving-and-extending-the-indication-for-a-flip-flop-procedure
#16
Ronen Ghinea, Shmuel Avital, Ephraim Katz, Baruch Shpitz, Ian White
BACKGROUND AND AIMS: Extended left hemicolectomy might be necessary for several indications. Once the resection is completed, it would be difficult or impossible to anastomose the transverse colon to the rectum due to the difficulty in mobilizing the transverse colon to reach for a tension-free rectal anastomosis. The aim of this report is to present the "Flip-Flop" technique to overcome this challenging situation. The procedure is based on a surgical technique published in the early 1960s to avoid permanent stoma after proctectomy and consists of changing the location of the right colon to reach the rectum...
October 28, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29060327/new-conducted-electrical-weapons-finite-element-modeling-of-safety-margins
#17
Dorin Panescu, Mark W Kroll, Michael A Brave
Introduction-We have previously published on the ventricular fibrillation (VF) risk with TASER® X26 conducted electrical weapon (CEW). Our risk model accounted for realistic body mass index distributions, modeled the effects of partial or oblique dart penetration, and used epidemiological CEW statistics. As new CEWs have become available to law enforcement, their cardiac safety profile was not quantified. Therefore, we applied our VF probability model to evaluate their cardiac risk. Methods and Results-An eXperimental Rotating-Field (XRF) waveform CEW and the X2 CEW are new 2-shot electrical weapon models designed to target a precise amount of delivered charge per pulse, 64 μC and 62 μC, respectively...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29054042/spontaneous-hemoperitoneum-in-pregnancy-ship-and-endometriosis-a-systematic-review-of-the-recent-literature
#18
REVIEW
Marit C I Lier, Romana F Malik, Johannes C F Ket, Cornelis B Lambalk, Ivo A Brosens, Velja Mijatovic
Spontaneous Hemoperitoneum in Pregnancy (SHiP), an unprovoked (nontraumatic) intraperitoneal bleeding in pregnancy (up to 42days postpartum), is associated with serious adverse pregnancy outcomes. To evaluate the clinical consequences of SHiP and its association with endometriosis, a systematic review was conducted according to the PRISMA guidelines. PubMed, Embase.com and Thomson Reuters/Web of Science were searched for articles published since the latest review (August 2008) until September 2016. After assessment for eligibility, forty-four articles were included in this systematic review, describing 59 cases of SHiP...
December 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29051872/synovial-hemangioma-of-the-knee-management-and-excellent-outcome-2-years-after-arthroscopic-synovectomy-in-a-25-year-old-male-with-a-20-year-history
#19
Akshdeep Singh Bawa, Rajnish Garg, Kaneeka Bhatnagar, Shekhar Singal
INTRODUCTION: Synovial hemangioma is a rare condition with <200 published case reports in world literature and is frequently misdiagnosed, leading to diagnostic delay of many years. This delay is even more significant if the patient comes from a rural background with a dearth of medical facilities in the area. This case had a lag of nearly 20 years from the time of onset of symptoms and the required management which is the maximum reported for any synovial hemangioma since most of them have been found and treated in adolescents...
May 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29046982/ureteroscopy-for-stone-disease-in-paediatric-population-is-safe-and-effective-in-medium-volume-and-high-volume-centres-evidence-from-a-systematic-review
#20
REVIEW
Shazna Rob, Patrick Jones, Amelia Pietropaolo, Stephen Griffin, Bhaskar K Somani
PURPOSE OF REVIEW: The incidence of urinary stone disease among the paediatric population is increasing. Whilst there has been a rise in the number of original studies published on ureteroscopy (URS) in children, critical review still remains under-reported. RECENT FINDINGS: A Cochrane style systematic review was performed to identify all original articles on URS (minimum of 25 cases) for stone disease in paediatric patients between Jan. 1996 and Dec. 2016. Based on the number of reported cases, centres were divided into medium (25-49 cases) and high (≥ 50 cases) volume studies...
October 18, 2017: Current Urology Reports
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