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Arteritis

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https://www.readbyqxmd.com/read/29472428/calcium-sign-of-thoracic-aortic-dissection-in-takayasu-s-arteritis
#1
Vorarit Lertsuwunseri, Pairoj Chattranukulchai, Monravee Tumkosit, Smonporn Boonyaratavej
No abstract text is available yet for this article.
February 22, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29471777/spontaneous-and-drug-induced-arteritis-polyarteritis-in-the-g%C3%A3-ttingen-minipig-review
#2
Zuhal Dincer, Virginie Piccicuto, Ursula Junker Walker, Andreas Mahl, Sean McKeag
Arteritis/polyarteritis occurs spontaneously in many species used in preclinical toxicology studies. In Göttingen minipigs, arteritis/polyarteritis is an occasionally observed background change. In the minipig, this finding differs in frequency and nature from age-related polyarteritis nodosa in rats or monkeys, and Beagle pain syndrome in dogs. In minipigs, it can be present in a single small- or medium-sized artery of an organ or a few organs and is most commonly recorded in the cardiac and extracardiac blood vessels, vagina, oviduct, rectum, epididymis, spinal cord, pancreas, urinary bladder, kidneys, and stomach...
February 2018: Toxicologic Pathology
https://www.readbyqxmd.com/read/29466947/stroke-as-an-atypical-initial-presentation-of-giant-cell-arteritis
#3
Tharsika Kuganesan, Allen R Huang
BACKGROUND: Giant cell arteritis (GCA) is an immune mediated inflammatory disease of medium and large arteries which afflicts older people. The classical presentation features include: headache, visual disturbances, and jaw claudication. Patients diagnosed with GCA have also been observed to be at higher risk for the subsequent development of strokes. CASE PRESENTATION: We describe a case of an 84-year old right-handed man who presented to hospital with dysarthria, dysphagia, right-sided facial drop, a history of generalized weakness and multiple falls...
February 21, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29465347/an-increased-major-vessel-uptake-by-18f-fdg-pet-ct-in-nih-criteria-clinical-inactive-patients-with-takayasu-s-arteritis
#4
Qing Han, Qiang Liang, Fei Kang, Jing Wang, Zhenbiao Wu, Ping Zhu
OBJECTIVES: The commonly adopted method of defining active disease in Takayasu's arteritis (TAK) is the definition used by the US National Institutes of Health (NIH). A gold standard in imaging techniques for assessing disease activity in TAK has not been clearly established and the creation of practical and valid tools represents a challenge. To assess whether 18F-FDG-PET/CT and NIH criteria show a good level of agreement in assessing disease activity of TAK patients. METHODS: 18F-FDG-PET/CT was performed in 17 patients with TAK...
February 7, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29465111/crp-and-esr-in-giant-cell-arteritis
#5
A Waller, A M Jawad
No abstract text is available yet for this article.
September 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29465101/tocilizumab-an-interleukin-6-inhibitor-a-steroid-sparing-agent-in-giant-cell-arteritis
#6
P Jobanputra, M Ford
No abstract text is available yet for this article.
September 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29464837/isolated-vascular-v-lesions-in-liver-allografts-how-to-approach-this-unusual-finding
#7
H L Stevenson, M M Prats, K Isse, A Zeevi, Y Avitzur, V L Ng, A J Demetris
According to the Banff criteria for kidney allografts, isolated vascular or "v" lesions are defined as intimal inflammation, age-inappropriate fibro-intimal hyperplasia, or both, without the presence of associated interstitial T cell-mediated rejection (TCMR). In general, these lesions portend a worse outcome for kidney allografts, particularly in those where the "v" lesions are identified in patients with co-existent donor specific antibodies (DSA) or later after transplantation. Although affected arteries are rarely sampled in liver allograft biopsies, we identified 9 patients at a mean of 1,805 days post-transplantation and compared these to matched controls...
February 21, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29461961/long-term-continuation-of-methotrexate-therapy-in-giant-cell-arteritis-patients-in-clinical-practice
#8
Leticia Leon, Luisa Rodriguez-Rodriguez, Dalifer Freites, Lucia Arietti, Inmaculada Morado, Cristina Vadillo, Jose Ramón Lamas, Benjamin Fernandez, Juan Angel Jover, Lydia Abasolo
No abstract text is available yet for this article.
January 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29455878/unusual-collateral-vascular-development-in-a-patient-with-takayasu-arteritis
#9
Zeyang Fan, Xiaoqiang Tong
No abstract text is available yet for this article.
March 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29451658/clinical-correlation-of-biopsy-results-in-patients-with-temporal-arteritis
#10
Volkan Yuksel, Orkut Guclu, Ebru Tastekin, Umit Halici, Serhat Huseyin, Volkan Inal, Suat Canbaz
OBJECTIVE: Temporal arteritis is systemic vasculitis of medium and large sized vessels. The lowest incidence rates were reported in Turkey, Japan and Israel. We aimed to investigate the results of patients with biopsy-proven temporal arteritis and those classified according to the American College of Rheumatology criteria from a low-incidence region for temporal arteritis. The results of our study are noteworthy, since there is limited data on pathologic diagnosis of temporal arteritis in Turkey...
November 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29444949/downregulation-of-eca-mir-128-in-seminal-exosomes-and-enhanced-expression-of-cxcl16-in-the-stallion-reproductive-tract-are-associated-with-long-term-persistence-of-equine-arteritis-virus
#11
Mariano Carossino, Pouya Dini, Theodore S Kalbfleisch, Alan T Loynachan, Igor F Canisso, Kathleen M Shuck, Peter J Timoney, R Frank Cook, Udeni B R Balasuriya
Equine arteritis virus (EAV) can establish long-term persistent infection in the reproductive tract of stallions and is shed in the semen. Previous studies showed that long-term persistence is associated with a specific allele of the CXCL16 gene ( CXCL16S ) and that persistent infection is maintained despite the presence of a local inflammatory and humoral and mucosal antibody responses. Here, we demonstrated that equine seminal exosomes (SEs) are enriched in a small subset of miRNAs. Most importantly, we demonstrated that long-term EAV persistence is associated with the downregulation of an SE-associated miRNA (eca-mir-128) and with an enhanced expression of CXCL16 in the reproductive tract, a putative target of eca-mir-128...
February 14, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29443797/outcome-of-endovascular-procedures-on-ocular-findings-in-takayasu-arteritis
#12
Mohit Dogra, Ashok Kumar, Priya Bajgai, Vishali Gupta, Reema Bansal, Mangat R Dogra, Rajesh Vijayvergiya, Ramandeep Singh
PURPOSE: To evaluate the outcome of endovascular procedures on ocular findings in patients with Takayasu arteritis. METHODS: Retrospective study of patients who underwent percutaneous endovascular stenting of aortic arch arteries for Takayasu arteritis (TA) and who had documented retinopathy findings before and after the procedure. Change in visual acuity, regression of retinopathy, and development of complications after endovascular procedure were studied over a follow-up of 6 months...
February 13, 2018: Retina
https://www.readbyqxmd.com/read/29440039/response-to-efficacy-and-safety-of-tocilizumab-in-patients-with-refractory-takayasu-arteritis-by-lee-and-song
#13
Yoshikazu Nakaoka
No abstract text is available yet for this article.
February 10, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29436372/the-acupuncture-therapeutic-approach-in-temporal-arteritis-vasculitis-a-case-report
#14
Yılmaz Sezgin
Temporal arteritis is a form of vasculitis that involves the large and medium-diameter arteries and leads to progressive headache. Symptoms may be accompanied by vision disorder, subfebrile temperature, fatigue, lack of appetite, weight loss, sweating and joint pains. While cortisone therapy reduces the symptoms, its effects in terms of improving quality of life are limited. We elected to benefit from the effects of acupuncture in order to reduce symptoms and increase quality of life in a case of temporal arteritis, a chronic disease...
December 26, 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/29435711/development-of-an-antigen-capture-elisa-for-the-quantitation-of-equine-arteritis-virus-in-culture-supernatant
#15
Ting Qi, Yue Hu, Zhe Hu, Shihua Zhao, Ann Cullinane, Pamela Lyons, Sarah Gildea, Xiaojun Wang
Quantitation of virions is one of the important indexes in virological studies. To establish a sensitive and rapid quantitative detection method for equine arteritis virus (EAV), an antigen-capture enzyme-linked immunosorbent assay (AC-ELISA) was developed by using two EAV nucleoprotein monoclonal antibodies (mAbs), 2B9 and 2B3, prepared in this study. After condition optimization, mAb 2B9 was used as the capture antibody, and HRP-labeled 2B3 was chosen as the detecting antibody. The AC-ELISA had a good standard curve when viral particles of the Bucyrus EAV strain were used as a reference standard...
February 12, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29434730/clinical-and-pathological-characteristics-of-igg4-related-interstitial-lung-disease
#16
Xiaoting Lv, Feng Gao, Qicai Liu, Sheng Zhang, Zhihua Huang, Yongping Zhu, Haiyang Zong, Quwen Li, Sanyan Li
IgG4-related interstitial lung disease (IgG4-RILD), which is characterized by increased IgG4 levels, IgG4 + plasma cell infiltration and irregular whorled fibrosis, is a recently described lung disorder that belongs to the group of systemic fibroinflammatory IgG4-related diseases (IgG4-RD). The aim of the present study was to improve the current knowledge regarding the specific clinical and histopathological characteristics of IgG4-RILD and to investigate its underlying immune mechanism in vivo . A total of 7 patients newly diagnosed with IgG4-RILD were enrolled in the present study (4 men and 3 women; mean age, 57 years; range, 29-71 years)...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29434141/takayasu-arteritis-coexisting-with-sclerosing-osteomyelitis
#17
Tsuyoshi Shirai, Riiza Hanaoka, Yusuke Goto, Ikuho Kojima, Yusho Ishii, Yousuke Hoshi, Yoko Fujita, Yuko Shirota, Hiroshi Fujii, Tomonori Ishii, Hideo Harigae
We report a rare case of a 27-year-old woman with Takayasu arteritis (TAK) complicated by diffuse sclerosing osteomyelitis. She first presented with sclerosing osteomyelitis of the right mandible without evidence of arteritis in the carotid arteries. Eight months later, she complained of left neck pain, and imaging studies revealed the presence of arteritis in the left carotid artery. She was diagnosed with TAK, and immunosuppressive treatment was initiated, which was effective for both the arteritis and the osteomyelitis...
February 9, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29431135/challenges-of-diagnosis-and-management-of-giant-cell-arteritis-in-general-practice-a-multimethods-study
#18
Toby Helliwell, Sara Muller, Samantha L Hider, James A Prior, Jane C Richardson, Christian D Mallen
BACKGROUND: In the UK, general practitioners (GPs) are usually the first medical contact for patients with suspected giant cell arteritis (GCA). While rare, it is critical not to miss, as delayed treatment can lead to significant complications including permanent visual loss. To date, little is known about the approach and challenges to diagnosis and management of GCA by GPs. OBJECTIVE: To investigate the diagnosis and management of patients with suspected GCA in UK general practice...
February 3, 2018: BMJ Open
https://www.readbyqxmd.com/read/29427826/tocilizumab-and-refractory-takayasu-disease-four-case-reports-and-systematic-review
#19
REVIEW
Paul Decker, Pierre Olivier, Jessie Risse, Stéphane Zuily, Denis Wahl
BACKGROUND: Relapses upon corticosteroids tapering and immunosuppressive agents are frequent in Takayasu arteritis (TA). Interleukin-6 is highly involved in physiopathology of TA. Many reports showed efficacy of tocilizumab (TCZ) in refractory TA cases. We report four cases and an updated literature review on the TCZ efficacy and safety in patients with TA. METHODS: Patients with TA defined by ACR 1990 criteria were included. Clinical, biological and imaging data were retrospectively reported...
February 7, 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29427822/large-vessel-involvement-and-aortic-dilation-in-giant-cell-arteritis-a-multicenter-study-of-549-patients
#20
REVIEW
Hubert de Boysson, Aurélie Daumas, Mathieu Vautier, Jean-Jacques Parienti, Eric Liozon, Marc Lambert, Maxime Samson, Mikael Ebba, Anael Dumont, Audrey Sultan, Bernard Bonnotte, Alain Manrique, Boris Bienvenu, David Saadoun, Achille Aouba
OBJECTIVES: Large-vessel involvement (LVI) can occur in giant-cell arteritis (GCA) and may represent a distinct disease subgroup with a higher risk for aortic dilation. This study aimed to better characterize the presentation and evolution of LVI in patients with GCA. PATIENTS AND METHODS: A retrospective multicenter study enrolled 248 GCA patients with LVI and 301 GCA patients without LVI on imaging. Factors associated with aortic dilation were identified in a multivariable model...
February 7, 2018: Autoimmunity Reviews
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