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https://www.readbyqxmd.com/read/29139385/-the-potential-of-artificial-intelligence-in-myology-a-viewpoint-from-a-non-robot
#1
Eytan Beckmann, Bruno Peyrou, Laure Gallay, Jean-Jacques Vignaux
No abstract text is available yet for this article.
November 2017: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/29139381/-titin-related-muscle-disorders-an-expanding-spectrum
#2
Ana Ferreiro, J Andoni Urtizberea
Titin-related diseases of the skeletal and cardiac muscles open a new, fruitful chapter of myology. Confined for a long time to a limited number of clinical entities, the phenotypic spectrum of titinopthies is nowadays expanding rapidly together with the discovery of many pathogenic mutations of the TTN gene. Like for many genes of large size, the fine tuning and use of high-throughput sequencing (NGS) constitutes a little revolution in the field. This powerful tool allows, although with real technical hurdles, the establishment of the definite diagnosis of titinopathy...
November 2017: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/29118960/from-the-padua-muscle-days-the-basic-and-applied-myology-and-the-european-journal-of-translational-myology-to-the-a-cm-carraro-foundation-for-translational-myology
#3
Ugo Carraro
As a young researched I had the option to work on skeletal muscle at the University of Padova, Italy. Introduced to the study of muscle denervation/reinnervation, I started a project on long term denervated muscle that still is my primary interest and took me from rodents' models of chronic muscle denervation to human spinal cord injury-related muscle denervation and its managements. On the way, I organized a series of conferences in Euganei Hills, Padua, Italy and an international journal, the Basic and Applied Myology...
June 27, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29098684/comparative-hindlimb-myology-of-foot-propelled-swimming-birds
#4
Glenna T Clifton, Jennifer A Carr, Andrew A Biewener
Several groups of birds have convergently evolved the ability to swim using their feet despite facing trade-offs with walking. However, swimming relative to terrestrial performance varies across these groups. Highly specialized divers, such as loons and grebes, excel at swimming underwater but struggle to stand on land, whereas species that primarily swim on the water surface, such as Mallards, retain the ability to move terrestrially. The identification of skeletal features associated with a swimming style and conserved across independent groups suggests that the hindlimb of foot-propelled swimming birds has adapted to suit the physical challenges of producing propulsive forces underwater...
November 3, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28762500/myology-of-the-forelimb-of-majungasaurus-crenatissimus-theropoda-abelisauridae-and-the-morphological-consequences-of-extreme-limb-reduction
#5
Sara H Burch
Forelimb reduction occurred independently in multiple lineages of theropod dinosaurs. Although tyrannosaurs are renowned for their tiny, two-fingered forelimbs, the degree of their reduction in length is surpassed by abelisaurids, which possess an unusual morphology distinct from that of other theropods. The forelimbs of abelisaurids are short but robust and exhibit numerous crests, tubercles, and scars that allow for inferences of muscle attachment sites. Phylogenetically based reconstructions of the musculature were used in combination with close examination of the osteology in the Malagasy abelisaurid Majungasaurus to create detailed muscle maps of the forelimbs, and patterns of the muscular and bony morphology were compared with those of extant tetrapods with reduced or vestigial limbs...
August 1, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28753203/management-of-neuromuscular-diseases-and-spinal-muscular-atrophy-in-latin-america
#6
REVIEW
S Monges, A L Rosa
Latin America (LA) has a population of ~645 million people distributed over 33 countries with marked political, cultural and economic differences. In LA, patients with inherited neuromuscular diseases (NMDs) often do not have access to specialized medical centers and many of them go undiagnosed. General management and care of spinal muscular dystrophy (SMA) patients in the region varies due to heterogeneous health care. An active generation of young clinical neurologists is being trained for the specialized care of SMA and other neuromuscular (NM) patients, both in the private and public sectors...
September 2017: Gene Therapy
https://www.readbyqxmd.com/read/28713538/2017spring-paduamuscledays-roots-and-byproducts
#7
EDITORIAL
Ugo Carraro
The second 2017 issue of EJTM volume 27 contains the collection of abstracts from the 2017Spring PaduaMuscleDays conference, that was held March 23-25 in Montegrotto, Euganei Hills, Padova, Italy. In addition to a brief history of the Padova Myology Meetings held during the last 30 years, the present and the future of the PaduaMuscleDays conference are discussed with special reference to new media and the options they offer to spread to a larger audience the results of the many workshops held in the Hotel Augustus conference hall and in the Aula Guariento of the Accademia Galileiana di Scienze, Lettere ed Arti, one of the hidden treasures of the medioeval Padua, Italy...
June 24, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/28610171/phylogenetic-relationships-and-morphology-of-the-i-pristimantis-leptolophus-i-species-group-amphibia-anura-brachycephaloidea-with-the-recognition-of-a-new-species-group-in-i-pristimantis-i-jim%C3%A3-nez-de-la-espada-1870
#8
Gustavo A González-Durán, Mariane Targino, Marco Rada, Taran Grant
We evaluate the monophyly and phylogenetic relationships of the Pristimantis leptolophus species group and describe its external morphology, osteology, and some myological characteristics. We also compare the P. leptolophus species group to other related species groups. The P. leptolophus group is not monophyletic due to the inclusion of P. acatallelus, formerly believed to be part of the P. devillei group. The revised P. leptolophus group is composed of nine named species and six unnamed species. Based on our results, we recognize a new species group, the P...
March 13, 2017: Zootaxa
https://www.readbyqxmd.com/read/28591339/oral-motor-and-electromyographic-characterization-of-adults-with-facial-fractures-a-comparison-between-different-fracture-severities
#9
Amanda Pagliotto da Silva, Fernanda Chiarion Sassi, Endrigo Bastos, Nivaldo Alonso, Claudia Regina Furquim de Andrade
OBJECTIVES: To characterize the oral motor system of adults with facial injuries and to compare the oral motor performance/function between two different groups. METHODS: An observational, descriptive, cross-sectional study was conducted in 38 patients presenting with facial trauma who were assigned to the Division of Orofacial Myology of a Brazilian School Hospital. Patients were divided into two groups: Group 1 (G1) consisted of 19 patients who were submitted to open reduction of at least one facial fracture, and Group 2 (G2) consisted of 19 individuals who were submitted to closed fracture reduction with maxillomandibular fixation...
May 2017: Clinics
https://www.readbyqxmd.com/read/28573152/cell-therapy-in-myology-dynamics-of-muscle-precursor-cell-death-after-intramuscular-administration-in-non-human-primates
#10
Daniel Skuk, Jacques P Tremblay
Cell therapy could be useful for the treatment of myopathies. A problem observed in mice, with different results and interpretations, is a significant death among the transplanted cells. We analyzed this problem in non-human primates, the animal model more similar to humans. Autologous or allogeneic myoblasts (with or without a reporter gene) were proliferated in vitro, labeled with [(14)C]thymidine, and intramuscularly injected in macaques. Some monkeys were immunosuppressed for long-term follow-up. Cell-grafted regions were biopsied at different intervals and analyzed by radiolabel quantification and histology...
June 16, 2017: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/28533965/reappraisal-of-the-extinct-seal-phoca-vitulinoides-from-the-neogene-of-the-north-sea-basin-with-bearing-on-its-geological-age-phylogenetic-affinities-and-locomotion
#11
Leonard Dewaele, Eli Amson, Olivier Lambert, Stephen Louwye
BACKGROUND: Discovered on the southern margin of the North Sea Basin, "Phoca" vitulinoides represents one of the best-known extinct species of Phocidae. However, little attention has been given to the species ever since its original 19th century description. Newly discovered material, including the most complete specimen of fossil Phocidae from the North Sea Basin, prompted the redescription of the species. Also, the type material of "Phoca" vitulinoides is lost. METHODS: "Phoca" vitulinoides is redescribed...
2017: PeerJ
https://www.readbyqxmd.com/read/28524458/forelimb-myology-of-carnivorous-marsupials-marsupialia-dasyuridae-implications-for-the-ancestral-body-plan-of-the-australidelphia
#12
Natalie M Warburton, Charlie-Rose Marchal
Carnivorous marsupials of the family Dasyuridae represent a more generalized anatomical condition of both craniodental and postcranial features in comparison to other groups of Australidelphian marsupials. Plesiomorphic characters include polyprotodont dentition, didactylous (rather than syndactylous) pedal morphology, the retention of clavicles and epipubic bones, and an unossified patelloid. In light of the anatomy of the postcranial skeleton, we hypothesized that the muscular anatomy of the Dasyuridae would likely display a range of plesiomorphic traits...
May 19, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28437841/characterizing-the-evolution-of-wide-gauge-features-in-stylopodial-limb-elements-of-titanosauriform-sauropods-via-geometric-morphometrics
#13
Paul V Ullmann, Matthew F Bonnan, Kenneth J Lacovara
Wide-gauge posture of titanosauriform sauropods remains an enigmatic peculiarity among terrestrial vertebrates. Here, two-dimensional geometric morphometrics and thin plate splines analyses were used to quantitatively analyze shape differences among sauropodomorph humeri and femora to identify how these elements may differ according to body gauge. Results demonstrate that titanosauriforms generally possess proportionately gracile humeri in comparison to other sauropods, with relatively more medially oriented humeral heads and proximally located deltopectoral crests...
April 24, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28316884/three-dimensional-visualisation-of-the-internal-anatomy-of-the-sparrowhawk-accipiter-nisus-forelimb-using-contrast-enhanced-micro-computed-tomography
#14
Fernanda Bribiesca-Contreras, William I Sellers
BACKGROUND: Gross dissection is a widespread method for studying animal anatomy, despite being highly destructive and time-consuming. X-ray computed tomography (CT) has been shown to be a non-destructive alternative for studying anatomical structures. However, in the past it has been limited to only being able to visualise mineralised tissues. In recent years, morphologists have started to use traditional X-ray contrast agents to allow the visualisation of soft tissue elements in the CT context...
2017: PeerJ
https://www.readbyqxmd.com/read/28089988/cell-scientist-to-watch-edgar-gomes
#15
(no author information available yet)
Edgar Gomes earned his PhD at the University of Coimbra in Portugal under the supervision of Carlos Duarte. He then travelled to the USA to train as a postdoctoral fellow in the laboratory of Gregg Gundersen at Columbia University in New York. Before moving back to Portugal in 2014, Edgar was a group leader in the Myology Institute at the University of Pierre and Marie Curie in Paris (France) as an INSERM Avenir Fellow. His lab investigates the mechanisms of nuclear positioning in skeletal muscle and in migrating cells...
January 15, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28078074/fes-in-europe-and-beyond-current-translational-research
#16
Christine Azevedo Coste, Winfried Mayr, Manfred Bijak, Antonio Musarò, Ugo Carraro
Capacity of adult neural and muscle tissues to respond to external Electrical Stimulation (ES) is the biological basis for the development and implementation of mobility impairment physiotherapy protocols and of related assistive technologies, e.g, Functional Electrical Stimulation (FES). All body tissues, however, respond to electrical stimulation and, indeed, the most successful application of FES is electrical stimulation of the heart to revert or limit effects of arrhythmias (Pace-makers and Defibrillators)...
September 15, 2016: European Journal of Translational Myology
https://www.readbyqxmd.com/read/27942892/erratum-to-laryngeal-transplantation-in-minipigs-vascular-myologic-and-functional-outcomes
#17
M A Birchall, P J Kingham, P J Murison, S M Ayling, R Burt, L Mitchard, A Jones, P Lear, C R Stokes, G Terenghi, M Bailey, P Macchiarini
No abstract text is available yet for this article.
January 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27932677/suite-of-clinically-relevant-functional-assays-to-address-therapeutic-efficacy-and-disease-mechanism-in-the-dystrophic-mdx-mouse
#18
Yafeng Song, Shira T Rosenblum, Leon Morales, Mihail Petrov, Christopher Greer, Samantha Globerman, Hansell H Stedman
Duchenne muscular dystrophy (DMD) is a progressive primary myodegenerative disease caused by a genetic deficiency of the 427-kDa cytoskeletal protein dystrophin. Despite its single-gene etiology, DMD's complex pathogenesis remains poorly understood, complicating the extrapolation from results of preclinical studies in genetic homologs to the design of informative clinical trials. Here we describe novel phenotypic assays which when applied to the mdx mouse resemble recently used primary end points for DMD clinical trials...
March 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27886207/characteristic-tetrapod-musculoskeletal-limb-phenotype-emerged-more-than-400-mya-in-basal-lobe-finned-fishes
#19
Rui Diogo, Peter Johnston, Julia L Molnar, Borja Esteve-Altava
Previous accounts of the origin of tetrapod limbs have postulated a relatively sudden change, after the split between extant lobe-finned fish and tetrapods, from a very simple fin phenotype with only two muscles to the highly complex tetrapod condition. The evolutionary changes that led to the muscular anatomy of tetrapod limbs have therefore remained relatively unexplored. We performed dissections, histological sections, and MRI scans of the closest living relatives of tetrapods: coelacanths and lungfish. Combined with previous comparative, developmental and paleontological information, our findings suggest that the characteristic tetrapod musculoskeletal limb phenotype was already present in the Silurian last common ancestor of extant sarcopterygians, with the exception of the autopod (hand/foot) structures, which have no clear correspondence with fish structures...
November 25, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27869067/-the-french-society-of-myology-shows-some-heart
#20
EDITORIAL
Gisèle Bonne, Guilhem Solé
No abstract text is available yet for this article.
November 2016: Médecine Sciences: M/S
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