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https://www.readbyqxmd.com/read/28329643/epidemiology-of-lentigo-maligna-and-lentigo-maligna-melanoma-in-the-netherlands-1989-2013
#1
Karin Greveling, Marlies Wakkee, Tamar Nijsten, Renate R Vane den Bos, Loes M Hollestein
Lentigo maligna (LM) is considered a precursor to LM melanoma (LMM). We assessed trends in LM and LMM incidence rates between 1989 and 2013 in the Netherlands, and estimated the risk of a LMM after LM. Data on newly diagnosed LM and LMM were obtained from the Netherlands Cancer Registry and PALGA (Dutch Pathology Database). Age-standardized incidence rates (European standardized rate [ESR]), estimated annual percentage changes (EAPC), and the cumulative incidence of LMM after LM were calculated. Between 1989-2013, 10,545 patients were diagnosed with a primary LM and 2,898 with a primary LMM in the Netherlands...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28325856/prevalence-of-undiagnosed-asymptomatic-bacteriuria-and-associated-risk-factors-during-pregnancy-a-cross-sectional-study-at-two-tertiary-centres-in-cairo-egypt
#2
Mohamed Abdel-Aziz Elzayat, Ashton Barnett-Vanes, Mohamed Farag Elmorsy Dabour, Feng Cheng
BACKGROUND: The prevalence of asymptomatic bacteriuria (ASB) during pregnancy is poorly understood in Egypt-a country with a high birth rate. OBJECTIVES: To determine the prevalence of ASB among pregnant women booking at El Hussein and Sayed Galal Hospitals in Al-Azhar University in Egypt; and to observe the relationship between ASB prevalence and risk factors such as socioeconomic level and personal hygiene. SETTING: Obstetrics and gynaecology clinics of 2 university hospitals in the capital of Egypt...
March 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28282931/bee-community-of-commercial-potato-fields-in-michigan-and-bombus-impatiens-visitation-to-neonicotinoid-treated-potato-plants
#3
Amanda L Buchanan, Jason Gibbs, Lidia Komondy, Zsofia Szendrei
We conducted a bee survey in neonicotinoid-treated commercial potato fields using bowl and vane traps in the 2016 growing season. Traps were placed outside the fields, at the field edges, and 10 and 30 m into the fields. We collected 756 bees representing 58 species, with Lasioglossum spp. comprising 73% of all captured bees. We found seven Bombus spp., of which B. impatiens was the only known visitor of potato flowers in our region. The majority of the bees (68%) were collected at the field edges and in the field margins...
March 9, 2017: Insects
https://www.readbyqxmd.com/read/28269012/cfd-analysis-of-strut-influence-on-blood-flow-in-stent-implanted-left-main-coronary-artery-bifurcation
#4
Yuya Yamada, Takahiro Tsukahara, Masahiro Motosuke, Yusuke Fujino
We numerically studied blood flows in a simulated branching pipe of coronary artery bifurcation, which is affected by stent implantation. We found that stent struts provide effects as guide vanes and blockages on the flow into circumflex branch. The former effect increases the flow rate and shear stress on the arteriosclerosis-prone site. The blockage effect may overwhelm the guide effect depending on a strut position against the inflow.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28262070/developing-a-website-to-demonstrate-clinical-holding-techniques
#5
Andrea Page, Alison Warren, Nicola Vanes
Healthcare staff routinely use clinical holding to help infants, children or young people stay still when treatment is being administered, to prevent children or young people from interfering with the treatment, or when invasive examinations are being carried out. However, healthcare staff rarely have any formal discussion with children and young people, or their parents, on the techniques used for clinical holding. Visual tools are important when talking to children or young people about their healthcare, and a website with images of clinical holds would allow staff to discuss relevant holds with their patients...
March 6, 2017: Nursing Children and Young People
https://www.readbyqxmd.com/read/28260833/development-of-noise-controls-for-longwall-shearer-cutting-drums
#6
Hugo E Camargo, Amanda S Azman, Lynn Alcorn
Noise-induced hearing loss is the second most pervasive disease in the mining industry. The exposure of miners to noise levels above the permissible exposure level results in hearing loss of approximately 80% of coal miners by retirement age. In addition, between 2002 and 2011, approximately 48% of longwall shearer operators were overexposed in coal mines in the United States. Previous research identified the two rotating cutting drums used by the longwall shearer to extract coal as the most significant sound-radiating components...
September 1, 2016: Noise Control Engineering Journal
https://www.readbyqxmd.com/read/28255996/distribution-of-the-characteristics-of-barbs-and-barbules-on-barn-owl-wing-feathers
#7
Matthias Weger, Hermann Wagner
Owls are known for the development of a silent flight. One conspicuous specialization of owl wings that has been implied in noise reduction and that has been demonstrated to change the aerodynamic behavior of the wing is a soft dorsal wing surface. The soft surface is a result of changes in the shape of feather barbs and barbules in owls compared with other bird species. We hypothesized that as the aerodynamic characteristics of a wing change along its chordwise and spanwise direction, so may the shape of the barbs and barbules...
March 3, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28227224/cfd-analysis-of-strut-influence-on-blood-flow-in-stent-implanted-left-main-coronary-artery-bifurcation
#8
Yuya Yamada, Takahiro Tsukahara, Masahiro Motosuke, Yusuke Fujino, Yuya Yamada, Takahiro Tsukahara, Masahiro Motosuke, Yusuke Fujino, Takahiro Tsukahara, Yuya Yamada, Yusuke Fujino, Masahiro Motosuke
We numerically studied blood flows in a simulated branching pipe of coronary artery bifurcation, which is affected by stent implantation. We found that stent struts provide effects as guide vanes and blockages on the flow into circumflex branch. The former effect increases the flow rate and shear stress on the arteriosclerosis-prone site. The blockage effect may overwhelm the guide effect depending on a strut position against the inflow.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28163870/features-of-owl-wings-that-promote-silent-flight
#9
REVIEW
Hermann Wagner, Matthias Weger, Michael Klaas, Wolfgang Schröder
Owls are an order of birds of prey that are known for the development of a silent flight. We review here the morphological adaptations of owls leading to silent flight and discuss also aerodynamic properties of owl wings. We start with early observations (until 2005), and then turn to recent advances. The large wings of these birds, resulting in low wing loading and a low aspect ratio, contribute to noise reduction by allowing slow flight. The serrations on the leading edge of the wing and the velvet-like surface have an effect on noise reduction and also lead to an improvement of aerodynamic performance...
February 6, 2017: Interface Focus
https://www.readbyqxmd.com/read/28160981/corrigendum-to-significance-of-dissolved-methane-in-effluents-of-anaerobically-treated-low-strength-wastewater-and-potential-for-recovery-as-an-energy-product-a-review-water-res-104-2016-520-531
#10
Brian C Crone, Jay L Garland, George A Sorial, Leland M Vane
No abstract text is available yet for this article.
February 1, 2017: Water Research
https://www.readbyqxmd.com/read/28135249/the-cdc42-rac1-regulator-cdgap-is-a-novel-e-cadherin-transcriptional-co-repressor-with-zeb2-in-breast-cancer
#11
Y He, J J Northey, A Pelletier, Z Kos, L Meunier, B Haibe-Kains, A-M Mes-Masson, J-F Côté, P M Siegel, N Lamarche-Vane
The loss of E-cadherin causes dysfunction of the cell-cell junction machinery, which is an initial step in epithelial-to-mesenchymal transition (EMT), facilitating cancer cell invasion and the formation of metastases. A set of transcriptional repressors of E-cadherin (CDH1) gene expression, including Snail1, Snail2 and Zeb2 mediate E-cadherin downregulation in breast cancer. However, the molecular mechanisms underlying the control of E-cadherin expression in breast cancer progression remain largely unknown...
January 30, 2017: Oncogene
https://www.readbyqxmd.com/read/28118925/treatment-of-the-first-bite-syndrome
#12
María Costales-Marcos, Fernando López Álvarez, Laura Fernández-Vañes, Justo Gómez, José Luis Llorente
First bite syndrome is a potential complication of surgery involving the infratemporal fossa, deep lobe of the parotid gland and parapharyngeal space. It is described as an acute and intense pain in the parotid region caused with the first bite of each meal. It is related to damage to sympathetic innervation of the parotid gland. Parasympathetic hyperactivation is believed to stimulate an exaggerated myoepithelial cell contraction causing pain. Usual analgesic treatments have poor results. Botulinum toxin type A causes parasympathetic nerve paralysis of the parotid gland and this fact would minimize salivation and decrease first bite syndrome...
January 21, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28110860/results-of-total-laryngectomy-as-treatment-for-locally-advanced-hypopharyngeal-cancer
#13
Patricia García-Cabo Herrero, Laura Fernández-Vañes, Fernando López Álvarez, César Álvarez Marcos, José Luis Llorente, Juan Pablo Rodrigo
INTRODUCTION AND OBJECTIVES: Total laryngectomy (TL), with eventual postoperative radiotherapy, has proven to be effective in treating cases of locally advanced hypopharyngeal cancer. The aim of this study was to analyse the oncological outcomes of this procedure in patients with hypopharyngeal cancer classified T3 and T4. METHODS: We studied 59 patients (33 T3 and 26 T4a) with primary squamous cell carcinoma of the hypopharynx treated with TL from 1998 to 2012...
January 19, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28106042/diverse-feather-shape-evolution-enabled-by-coupling-anisotropic-signalling-modules-with-self-organizing-branching-programme
#14
Ang Li, Seth Figueroa, Ting-Xin Jiang, Ping Wu, Randall Widelitz, Qing Nie, Cheng-Ming Chuong
Adaptation of feathered dinosaurs and Mesozoic birds to new ecological niches was potentiated by rapid diversification of feather vane shapes. The molecular mechanism driving this spectacular process remains unclear. Here, through morphology analysis, transcriptome profiling, functional perturbations and mathematical simulations, we find that mesenchyme-derived GDF10 and GREM1 are major controllers for the topologies of rachidial and barb generative zones (setting vane boundaries), respectively, by tuning the periodic-branching programme of epithelial progenitors...
January 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/28102214/corrigendum-wnk1-kinase-balances-t-cell-adhesion-versus-migration-in-vivo
#15
Robert Köchl, Flavian Thelen, Lesley Vanes, Tiago F Brazão, Kathryn Fountain, Jian Xie, Chou-Long Huang, Ruth Lyck, Jens V Stein, Victor L J Tybulewicz
No abstract text is available yet for this article.
January 19, 2017: Nature Immunology
https://www.readbyqxmd.com/read/28098457/surface-forces-and-rheology-of-titanium-dioxide-in-the-presence-of-dicarboxylic-acids-from-molecular-interactions-to-yield-stress
#16
E-Jen Teh, Yee-Kwong Leong, Vincent S J Craig
The surface forces and yield stress of titanium dioxide were measured in the presence of dicarboxylic acids in order to understand the molecular basis for the observed rheological response. The yield stress was measured using the static vane technique, and the surface forces were characterized using an atomic force microscope. The trans and cis isomers of butenedioic acid (fumaric and maleic acids, respectively) were chosen as the relative orientation of the carboxylic groups differs substantially. This enables us to test the hypothesis that an increase in adhesion leads to an increase in yield stress as a consequence of the dicarboxylic acids participating in highly directed bridging...
January 31, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28070276/a-hypothesis-to-explain-accuracy-of-wasp-resemblances
#17
Michael Boppré, Richard I Vane-Wright, Wolfgang Wickler
Mimicry is one of the oldest concepts in biology, but it still presents many puzzles and continues to be widely debated. Simulation of wasps with a yellow-black abdominal pattern by other insects (commonly called "wasp mimicry") is traditionally considered a case of resemblance of unprofitable by profitable prey causing educated predators to avoid models and mimics to the advantage of both (Figure 1a). However, as wasps themselves are predators of insects, wasp mimicry can also be seen as a case of resemblance to one's own potential antagonist...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28070227/disposable-fluidic-actuators-for-miniature-in-vivo-surgical-robotics
#18
Abolfazl Pourghodrat, Carl A Nelson
Fusion of robotics and minimally invasive surgery (MIS) has created new opportunities to develop diagnostic and therapeutic tools. Surgical robotics is advancing from externally actuated systems to miniature in-vivo robotics. However, with miniaturization of electric-motor-driven surgical robots, there comes a trade-off between the size of the robot and its capability. Slow actuation, low load capacity, sterilization difficulties, leaking electricity and transferring produced heat to tissues, and high cost are among the key limitations of the use of electric motors in in-vivo applications...
March 2017: Journal of Medical Devices
https://www.readbyqxmd.com/read/27987218/the-effects-of-tracheal-tube-cuffs-filled-with-air-saline-or-alkalinised-lidocaine-on-haemodynamic-changes-and-laryngotracheal-morbidity-in-children-a-randomised-controlled-trial
#19
S M F Soares, V M Arantes, M P Módolo, V J B Dos Santos, L A Vane, L H Navarro E Lima, L G Braz, P do Nascimento, N S P Módolo
We studied the effects of tracheal tube cuffs filled with air, saline or alkalinised lidocaine on haemodynamic changes during tracheal extubation and postoperative laryngotracheal morbidity in children. We randomly allocated 164 children aged 3-13 years undergoing general anaesthesia to one of four groups; tracheal tube cuffs filled with air (n = 41); saline (n = 41); alkalinised lidocaine 0.5% (n = 41); or alkalinised lidocaine 1% (n = 41). Intracuff pressure was monitored and maintained below 20 cmH2 O. The mean (SD) increases in systolic blood pressure after tracheal extubation compared with before extubation were 10...
April 2017: Anaesthesia
https://www.readbyqxmd.com/read/27926862/vav-proteins-are-key-regulators-of-card9-signaling-for-innate-antifungal-immunity
#20
Susanne Roth, Hanna Bergmann, Martin Jaeger, Assa Yeroslaviz, Konstantin Neumann, Paul-Albert Koenig, Clarissa Prazeres da Costa, Lesley Vanes, Vinod Kumar, Melissa Johnson, Mauricio Menacho-Márquez, Bianca Habermann, Victor L Tybulewicz, Mihai Netea, Xosé R Bustelo, Jürgen Ruland
Fungal infections are major causes of morbidity and mortality, especially in immunocompromised individuals. The innate immune system senses fungal pathogens through Syk-coupled C-type lectin receptors (CLRs), which signal through the conserved immune adaptor Card9. Although Card9 is essential for antifungal defense, the mechanisms that couple CLR-proximal events to Card9 control are not well defined. Here, we identify Vav proteins as key activators of the Card9 pathway. Vav1, Vav2, and Vav3 cooperate downstream of Dectin-1, Dectin-2, and Mincle to engage Card9 for NF-κB control and proinflammatory gene transcription...
December 6, 2016: Cell Reports
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