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Mixed method research

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https://www.readbyqxmd.com/read/28635973/deconstructing-decisions-to-initiate-maintain-or-discontinue-adjuvant-endocrine-therapy-in-breast-cancer-survivors-a-mixed-methods-study
#1
Shirley M Bluethmann, Caitlin C Murphy, Jasmin A Tiro, Michelle A Mollica, Sally W Vernon, Leona Kay Bartholomew
PURPOSE/OBJECTIVES: Adjuvant endocrine therapy (AET) has been shown to improve survival in hormone receptor-positive breast cancer survivors, but as many as half do not complete recommended treatment. Management of medication-related side effects and engagement with providers are two potentially modifiable factors, but their associations with adherence are not well understood. The aims were to build on survey results to qualitatively explore survivors' experiences with prescribed AET to (a) describe appraisal and management of AET side effects and (b) deconstruct decisions to initiate, discontinue, or maintain AET...
May 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28635526/a-randomized-lifestyle-intervention-preventing-gestational-diabetes-effects-on-self-rated-health-from-pregnancy-to-postpartum
#2
Elina Engberg, Beata Stach-Lempinen, Kristiina Rönö, Hannu Kautiainen, Johan G Eriksson, Saila B Koivusalo
INTRODUCTION: The purpose was to examine the effects of a randomized lifestyle intervention on self-rated health from pregnancy to postpartum in participants at high risk for gestational diabetes mellitus. METHODS: We included 266 women with a history of gestational diabetes and/or prepregnancy BMI ≥30 kg/m(2). The intervention group (n = 144) received individualized counseling on diet, physical activity, and weight management from trained nurses at six timepoints between the first trimester of pregnancy and 12 months postpartum, and met three times with a dietitian...
February 9, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28634247/clinicians-perceptions-of-screening-for-food-insecurity-in-suburban-pediatric-practice
#3
Deepak Palakshappa, Aditi Vasan, Saba Khan, Leah Seifu, Chris Feudtner, Alexander G Fiks
BACKGROUND: National organizations recommend pediatricians screen for food insecurity (FI). Although there has been growing research in urban practices, little research has addressed FI screening in suburban practices. We evaluated the feasibility, acceptability, and impact of screening in suburban practices. METHODS: We conducted a mixed methods study that implemented FI screening in 6 suburban pediatric primary care practices. We included all children presenting for either a 2-, 15-, or 36-month well-child visit (N = 5645)...
June 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/28633064/an-innovative-approach-to-bioremediation-of-mercury-contaminated-soils-from-industrial-mining-operations
#4
Damien McCarthy, Grant C Edwards, Mae S Gustin, Andrew Care, Matthieu B Miller, Anwar Sunna
Soils contaminated with mercury (Hg) have proved expensive and logistically difficult to remediate. Research continues into finding suitable environmentally-friendly and efficient ways of achieving this end. Bioremediation is an option, which employs the strategies microorganisms have evolved to deal with Hg. One microbial strategy involves uptake and intracellular volatilisation of mercuric ions, which passively diffuse from the cell and back into the atmosphere. In this work, Pseudomonas veronii cells grown to stationary phase were immobilised in a xanthan gum-based biopolymer via encapsulation...
June 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28633042/feasibility-study-of-a-family-focused-intervention-to-improve-outcomes-for-children-with-fasd
#5
Natasha Reid, Sharon Dawe, Paul Harnett, Doug Shelton, Lauren Hutton, Frances O'Callaghan
BACKGROUND: Growing evidence shows that children with fetal alcohol spectrum disorder (FASD) can benefit from interventions, and specifically interventions focused on improving self-regulation. However, novel ways of improving outcomes for children with FASD need further investigation so that programs target not only the individual child but also the family context, which includes the parent-child relationship. AIMS: The current study aimed to evaluate the feasibility of an adapted version of the Parents under Pressure (PuP) program that addresses self-regulatory processes, through improving the parent-child relationship and the use of mindfulness-based strategies for both children and parents...
June 17, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28632247/antecedents-and-outcomes-of-uncertainty-in-older-adults-with-cancer-a-scoping-review-of-the-literature
#6
Vida Ghodraty Jabloo, Shabbir M H Alibhai, Margaret Fitch, Ann E Tourangeau, Ana Patricia Ayala, Martine T E Puts
PROBLEM IDENTIFICATION: Uncertainty is a major source of distress for cancer survivors. Because cancer is primarily a disease of older adults, a comprehensive understanding of the antecedents and outcomes of uncertainty in older adults with cancer is essential. 
. LITERATURE SEARCH: MEDLINE®, PsycINFO®, Scopus, and CINAHL® were searched from inception to December 2015. Medical Subject Headings (MeSH) terms and free text words were used for the search concepts, including neoplasms, uncertainty, and aging...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28632013/task-demands-in-osces-influence-learning-strategies
#7
Alexandre Lafleur, Jonathan Laflamme, Jimmie Leppink, Luc Côté
THEORY: Models on pre-assessment learning effects confirmed that task demands stand out among the factors assessors can modify in an assessment to influence learning. However, little is known about which tasks in objective structured clinical examinations (OSCEs) improve students' cognitive and metacognitive processes. Research is needed to support OSCE designs that benefit students' metacognitive strategies when they are studying, reinforcing a hypothesis-driven approach. With that intent, hypothesis-driven physical examination (HDPE) assessments ask students to elicit and interpret findings of the physical exam to reach a diagnosis ("Examine this patient with a painful shoulder to reach a diagnosis")...
March 2, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28630712/quantifying-drivers-of-wild-pig-movement-across-multiple-spatial-and-temporal-scales
#8
Shannon L Kay, Justin W Fischer, Andrew J Monaghan, James C Beasley, Raoul Boughton, Tyler A Campbell, Susan M Cooper, Stephen S Ditchkoff, Steve B Hartley, John C Kilgo, Samantha M Wisely, A Christy Wyckoff, Kurt C VerCauteren, Kim M Pepin
BACKGROUND: The movement behavior of an animal is determined by extrinsic and intrinsic factors that operate at multiple spatio-temporal scales, yet much of our knowledge of animal movement comes from studies that examine only one or two scales concurrently. Understanding the drivers of animal movement across multiple scales is crucial for understanding the fundamentals of movement ecology, predicting changes in distribution, describing disease dynamics, and identifying efficient methods of wildlife conservation and management...
2017: Movement Ecology
https://www.readbyqxmd.com/read/28630507/analysis-of-the-student-experience-in-an-attending-pharmacist-model-general-medicine-advanced-pharmacy-practice-experience
#9
Teresa A O'Sullivan, Carmen Lau, Erin Sy, Hana Moogk, Stanley S Weber, Jennifer Danielson
Objective. To characterize and determine the quality of the student experience in an attending pharmacist model (APM). Methods. In-depth interviews were conducted with students completing an advanced pharmacy practice experience (APPE) at two general medicine services using the APM over a 2-year time period. Quantitative information about student learning and interprofessional interactions were extracted from student evaluations of the site. Data from the mixed model were analyzed to identify strengths of the APM and areas needing improvement...
May 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28630086/psychosocial-therapy-for-parkinson-s-related-dementia-study-protocol-for-the-invest-randomised-controlled-trial
#10
Sheree A McCormick, Kathryn R McDonald, Sabina Vatter, Vasiliki Orgeta, Ellen Poliakoff, Sarah Smith, Monty A Silverdale, Bo Fu, Iracema Leroi
INTRODUCTION: Parkinson's disease (PD) with mild cognitive impairment (MCI-PD) or dementia (PDD) and dementia with Lewy bodies (DLB) are characterised by motor and 'non-motor' symptoms which impact on quality of life. Treatment options are generally limited to pharmacological approaches. We developed a psychosocial intervention to improve cognition, quality of life and companion burden for people with MCI-PD, PDD or DLB. Here, we describe the protocol for a single-blind randomised controlled trial to assess feasibility, acceptability and tolerability of the intervention and to evaluate treatment implementation...
June 19, 2017: BMJ Open
https://www.readbyqxmd.com/read/28629488/supporting-in-an-existential-crisis-a-mixed-methods-evaluation-of-a-training-model-in-palliative-care
#11
Lisa Sand, Mariann Olsson, Peter Strang
BACKGROUND: Palliative care staff often report that they lack the skills and confidence to provide support during an existential crisis. Consequently, there is a definite need for a training program in this area. OBJECTIVE: Our aim was to investigate whether a training model could give palliative care staff increased knowledge, awareness, and preparedness-all useful tools for providing support. METHODS: A mixed-methods research design was used...
June 20, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28628837/the-influence-of-essential-oils-from-xiang-fu-si-wu-decoction-on-its-non-volatile-components-and-its-application-for-pharmacokinetics-in-normal-rats
#12
Ying Pan, Dawei Qian, Pei Liu, Yang Zhang, Zhenhua Zhu, Li Zhang, Jin-Ao Duan
Xiang-Fu-Si-Wu Decoction (XFSWD) has been used to treat gynecology diseases in clinical practice for hundreds of years in China, especially for primary dysmenorrheal of QiZhi Type. In previous researches, both essential oils (XEO) and non-volatile components (NXEO) extracted from XFSWD showed significant pharmacological activities, but the influence of XEO on NXEO was unclear. The purpose of this paper was to develop a validated analytical method for simultaneous determination of ten components including Vanillic acid, Ferulic acid, Caffeic acid, Gallic acid, Paeoniflorin, Albiflorin, Tetrahydropalmatine, Protopine, Berberine and Tetrahydrocolumbamine, and to compare the pharmacokinetic parameters of these components to illustrate the influences of XEO on NXEO in normal rats...
June 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28627934/adult-patient-decision-making-regarding-implantation-of-complex-cardiac-devices-a-scoping-review
#13
Alison Malecki-Ketchell, Paul Marshall, Joan Maclean
BACKGROUND: Complex cardiac rhythm management device (CRMD) therapy provides an important treatment option for people at risk of sudden cardiac death. Despite the survival benefit, device implantation is associated with significant physical and psychosocial concerns presenting considerable challenges for the decision-making process surrounding CRMD implantation for patients and physicians. AIMS: The purpose of this scoping review was to explore what is known about how adult (>16 years) patients make decisions regarding implantation of CRMD therapy...
June 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28627356/aquatic-therapy-for-children-with-duchenne-muscular-dystrophy-a-pilot-feasibility-randomised-controlled-trial-and-mixed-methods-process-evaluation
#14
Daniel Hind, James Parkin, Victoria Whitworth, Saleema Rex, Tracey Young, Lisa Hampson, Jennie Sheehan, Chin Maguire, Hannah Cantrill, Elaine Scott, Heather Epps, Marion Main, Michelle Geary, Heather McMurchie, Lindsey Pallant, Daniel Woods, Jennifer Freeman, Ellen Lee, Michelle Eagle, Tracey Willis, Francesco Muntoni, Peter Baxter
BACKGROUND: Duchenne muscular dystrophy (DMD) is a rare disease that causes the progressive loss of motor abilities such as walking. Standard treatment includes physiotherapy. No trial has evaluated whether or not adding aquatic therapy (AT) to land-based therapy (LBT) exercises helps to keep muscles strong and children independent. OBJECTIVES: To assess the feasibility of recruiting boys with DMD to a randomised trial evaluating AT (primary objective) and to collect data from them; to assess how, and how well, the intervention and trial procedures work...
May 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28627296/sexual-violation-of-patients-by-physicians-a-mixed-methods-exploratory-analysis-of-101-cases
#15
James M DuBois, Heidi A Walsh, John T Chibnall, Emily E Anderson, Michelle R Eggers, Mobolaji Fowose, Hannah Ziobrowski
A mixed-method, exploratory design was used to examine 101 cases of sexual violations in medicine. The study involved content analysis of cases to characterize the physicians, patient-victims, the practice setting, kinds of sexual violations, and consequences to the perpetrator. In each case, a criminal law framework was used to examine how motives, means, and opportunity combined to generate sexual misconduct. Finally, cross-case analysis was performed to identify clusters of causal factors that explain specific kinds of sexual misconduct...
June 1, 2017: Sexual Abuse: a Journal of Research and Treatment
https://www.readbyqxmd.com/read/28625422/online-version-of-the-self-administered-food-frequency-questionnaire-for-the-japan-public-health-center-based-prospective-study-for-the-next-generation-jphc-next-protocol-relative-validity-usability-and-comparison-with-a-printed-questionnaire
#16
Erika Kato, Ribeka Takachi, Junko Ishihara, Yuri Ishii, Shizuka Sasazuki, Norie Sawada, Motoki Iwasaki, Yurie Shinozawa, Jun Umezawa, Junta Tanaka, Yuta Yokoyama, Kaori Kitamura, Kazutoshi Nakamura, Shoichiro Tsugane
BACKGROUND: Online dietary assessment tools offer advantages over printed questionnaires, such as the automatic and direct data storage of answers, and have the potential to become valuable research methods. We developed an online survey system (web-FFQ) for the existing printed FFQ used in the JPHC-NEXT protocol, the platform of a large-scale genetic cohort study. Here, we examined the validity of ranking individuals according to dietary intake using this web-FFQ and its usability compared with the printed questionnaire (print-FFQ) for combined usage...
June 15, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28625111/successful-adaptation-of-a-research-methods-course-in-south-america
#17
Leonardo Tamariz, Diego Vasquez, Cecilia Loor, Ana Palacio
BACKGROUND: South America has low research productivity. The lack of a structured research curriculum is one of the barriers to conducting research. OBJECTIVE: To report our experience adapting an active learning-based research methods curriculum to improve research productivity at a university in Ecuador. DESIGN: We used a mixed-method approach to test the adaptation of the research curriculum at Universidad Catolica Santiago de Guayaquil...
2017: Medical Education Online
https://www.readbyqxmd.com/read/28624834/quantitative-methods-in-psychological-aging-research-a-mini-review
#18
Paolo Ghisletta, Stephen Aichele
As research on psychological aging moves forward, it is increasingly important to accurately assess longitudinal changes in psychological processes and to account for their (often complex) associations with sociodemographic, lifestyle, and health-related variables. Traditional statistical methods, though time tested and well documented, are not always satisfactory for meeting these aims. In this mini-review, we therefore focus the discussion on recent statistical advances that may be of benefit to researchers in psychological aging but that remain novel in our area of study...
June 17, 2017: Gerontology
https://www.readbyqxmd.com/read/28622681/a-mixed-representation-based-multiobjective-evolutionary-algorithm-for-overlapping-community-detection
#19
Lei Zhang, Hebin Pan, Yansen Su, Xingyi Zhang, Yunyun Niu
Designing multiobjective evolutionary algorithms (MOEAs) for community detection in complex networks has attracted much attention of researchers recently. However, most of the existing methods focus on addressing the task of nonoverlapping community detection, where each node must belong to one and only one community. In fact, communities are often overlapped with each other in many real-world networks, thus it is necessary to design overlapping community detection algorithms. To this end, this paper proposes a mixed representation-based MOEA (MR-MOEA) for overlapping community detection...
June 13, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28622621/development-of-an-ultra-fast-liquid-chromatography-tandem-mass-spectrometry-method-for-simultaneous-determination-of-seven-flavonoids-in-rat-plasma-application-to-a-comparative-pharmacokinetic-investigation-of-ginkgo-biloba-extract-and-single-pure-ginkgo-flavonoids
#20
Tianyang Wang, Jie Xiao, Huiping Hou, Pei Li, Ziyue Yuan, Huarong Xu, Ran Liu, Qing Li, Kaishun Bi
For deeper pharmacokinetic investigation and further curative application of ginkgo flavonoids, a delicate, efficient and precise UFLC-MS/MS technique for synchronous quantitation of seven flavonoids, apigenin, luteolin, naringenin, quercetin, diosmetin, kaempferol and isorhamnetin in rat plasma has been established. After mixing with the internal standard (IS) linarin, bio-samples were pretreated via ethyl acetate for liquid-liquid extraction, then isolated at 0.2ml/min flow rate on a Venusil MP C18 chromatographic column (100mm×2...
May 30, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
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