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Mixed method research

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https://www.readbyqxmd.com/read/28346386/a-mixed-methods-examination-of-physical-activity-and-sedentary-time-in-overweight-and-obese-south-asian-men-living-in-the-united-kingdom
#1
Amir Emadian, Janice Thompson
South Asian men living in the UK have higher rates of central obesity and Type 2 Diabetes Mellitus (T2DM) compared with their white British counterparts. Physical activity (PA) and sedentary time (ST) are important risk factors for the development of T2DM. The purpose of this study was to objectively measure PA, ST, and to explore the factors influencing these behaviours in this high-risk population. A mixed-methods cross-sectional research design was employed, including the quantification of PA and ST using the self-report International Physical Activity Questionnaire (IPAQ)-long form and accelerometry in overweight and obese UK South Asian men (n = 54), followed by semi-structured interviews in a purposive sub-sample to explore the factors influencing PA and ST (n = 31)...
March 27, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28346204/restructuring-the-art-of-health-by-pharmacists-formulation-designs-with-oral-vehicles-teaching-pharmacy-students
#2
Rita Benischek
Compounding pharmacists, responsible for appropriate preparation of medications, coordinate with other professionals to reach optimal therapeutic options for patients. This review summarizes proprietary oral vehicles or suspensions focusing on available information or updated data from suppliers. Research has advanced methods with revised applications, cutting-edge safety considerations, beyond-use dating provisions for technical assistance, and evidence to review and teach pharmacy students the opportunities in the choices of an oral vehicle...
March 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28345474/assessment-treatment-goals-and-interventions-for-oedema-lymphoedema-in-palliative-care
#3
Sinead Cobbe, Shirley Real, Sinead Slattery
BACKGROUND: Little is known about the treatment of oedema in palliative care patients. AIM: To outline the assessment, goals, and interventions for patients with oedema. METHOD: A 6-month chart review of a specialist physiotherapy-led oedema service was carried out. RESULTS: Of the sample group (n=63), 28.6% of patients had lymphoedema, 15.9% had non-lymphatic oedema, 46% had mixed oedema and 9.8% had lymphorrhoea; 58 patients (92%) had cancer...
March 16, 2017: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/28344720/resetting-the-compass-exploring-the-implicit-messages-of-orientation-to-a-community-engaged-medical-school
#4
Rachel Ellaway, Tim Dubé, Gerry Cooper, Lisa Graves
BACKGROUND: Although students' transition into medical school is a critical step in their professional journey, orientation has been relatively under-researched, particularly with regard to its intersections with schools' social missions. This paper reports on a study looking at the implicit messages of orientation to the Northern Ontario School of Medicine's undergraduate program. METHODS: An extended mixed methods study was conducted to look at different aspects of the School's Orientation Week...
February 2017: Canadian Medical Education Journal
https://www.readbyqxmd.com/read/28344519/assessment-of-repli-g-multiple-displacement-whole-genome-amplification-wga-techniques-for-metagenomic-applications
#5
Sofia Ahsanuddin, Ebrahim Afshinnekoo, Jorge Gandara, Mustafa Hakyemezoğlu, Daniela Bezdan, Samuel Minot, Nick Greenfield, Christopher E Mason
Amplification of minute quantities of DNA is a fundamental challenge in low-biomass metagenomic and microbiome studies because of potential biases in coverage, guanine-cytosine (GC) content, and altered species abundances. Whole genome amplification (WGA), although widely used, is notorious for introducing artifact sequences, either by amplifying laboratory contaminants or by nonrandom amplification of a sample's DNA. In this study, we investigate the effect of REPLI-g multiple displacement amplification (MDA; Qiagen, Valencia, CA, USA) on sequencing data quality and species abundance detection in 8 paired metagenomic samples and 1 titrated, mixed control sample...
March 21, 2017: Journal of Biomolecular Techniques: JBT
https://www.readbyqxmd.com/read/28344514/australia-s-first-transition-to-professional-practice-in-primary-care-program-for-graduate-registered-nurses-a-pilot-study
#6
Christina Aggar, Jacqueline Bloomfield, Tamsin H Thomas, Christopher J Gordon
BACKGROUND: Increases in ageing, chronic illness and complex co-morbidities in the Australian population are adding pressure to the primary care nursing workforce. Initiatives to attract and retain nurses are needed to establish a sustainable and skilled future primary care nursing workforce. We implemented a transition to professional practice program in general practice settings for graduate nurses and evaluated graduate nurse competency, the graduate nurse experience and program satisfaction...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28343712/nurses-on-health-care-governing-boards-an%C3%A2-integrative%C3%A2-review
#7
Lisa J Sundean, E Carol Polifroni, Kathryn Libal, Jacqueline M McGrath
BACKGROUND: Nurses are key change agents in health care; yet, nurses have not been sufficiently engaged on boards to shape decision making. Without an equal voice in the boardroom, nurses cannot fulfill their professional obligation to society. PURPOSE: The purpose of this study was to understand the progression in research focus and recommendations over time about nurses on boards (NOB), identify research gaps, and make research/practice recommendations. METHODS: An integrative review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines (2009) for data evaluation and analysis...
January 21, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/28343328/skeletal-development-of-the-hand-and-wrist-digital-bone-age-companion-a-suitable-alternative-to-the-greulich-and-pyle-atlas-for-bone-age-assessment
#8
Paul M Bunch, Talissa A Altes, Joan McIlhenny, James Patrie, Cree M Gaskin
PURPOSE: To assess reader performance and subjective workflow experience when reporting bone age studies with a digital bone age reference as compared to the Greulich and Pyle atlas (G&P). We hypothesized that pediatric radiologists would achieve equivalent results with each method while digital workflow would improve speed, experience, and reporting quality. MATERIALS AND METHODS: IRB approval was obtained for this HIPAA-compliant study. Two pediatric radiologists performed research interpretations of bone age studies randomized to either the digital (Digital Bone Age Companion, Oxford University Press) or G&P method, generating reports to mimic clinical workflow...
March 25, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28343023/classification-of-footwear-outsole-patterns-using-fourier-transform-and-local-interest-points
#9
Nicole Richetelli, Mackenzie C Lee, Carleen A Lasky, Madison E Gump, Jacqueline A Speir
Successful classification of questioned footwear has tremendous evidentiary value; the result can minimize the potential suspect pool and link a suspect to a victim, a crime scene, or even multiple crime scenes to each other. With this in mind, several different automated and semi-automated classification models have been applied to the forensic footwear recognition problem, with superior performance commonly associated with two different approaches: correlation of image power (magnitude) or phase, and the use of local interest points transformed using the Scale Invariant Feature Transform (SIFT) and compared using Random Sample Consensus (RANSAC)...
March 4, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28343021/application-of-mixed-methods-design-in-community-engaged-research-lessons-learned-from-an-evidence-based-intervention-for-latinos-with-chronic-illness-and-minor-depression
#10
Claudia X Aguado Loi, Moya L Alfonso, Isabella Chan, Kelsey Anderson, Dinorah Dina Martinez Tyson, Junius Gonzales, Jaime Corvin
The purpose of this paper is to share lessons learned from a collaborative, community-informed mixed-methods approach to adapting an evidence-based intervention to meet the needs of Latinos with chronic disease and minor depression and their family members. Mixed-methods informed by community-based participatory research (CBPR) were employed to triangulate multiple stakeholders' perceptions of facilitators and barriers of implementing the adapted intervention in community settings. Community partners provided an insider perspective to overcome methodological challenges...
December 24, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28340573/a-questionnaire-measuring-staff-perceptions-of-lean-adoption-in-healthcare-development-and-psychometric-testing
#11
Monica Kaltenbrunner, Lars Bengtsson, Svend Erik Mathiassen, Maria Engström
BACKGROUND: During the past decade, the concept of Lean has spread rapidly within the healthcare sector, but there is a lack of instruments that can measure staff's perceptions of Lean adoption. Thus, the aim of the present study was to develop a questionnaire measuring Lean in healthcare, based on Liker's description of Lean, by adapting an existing instrument developed for the service sector. METHODS: A mixed-method design was used. Initially, items from the service sector instrument were categorized according to Liker's 14 principles describing Lean within four domains: philosophy, processes, people and partners and problem-solving...
March 24, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28340567/improving-the-provision-of-services-to-young-people-from-refugee-backgrounds-with-comorbid-mental-health-and-substance-use-problems-addressing-the-barriers
#12
Miriam Posselt, Karalyn McDonald, Nicholas Procter, Charlotte de Crespigny, Cherrie Galletly
BACKGROUND: South Australia (SA) has resettled 151,134 refugees in the last ten years (Department of Immigration and Border Protection, Settlement reporting facility, 2014). Northern metropolitan Adelaide, an area which experiences significant social disadvantage, has received a significant number of (predominantly young) refugees. Research indicates that refugee youth are at elevated risk of mental health (MH) and alcohol and other drug (AOD) problems. These factors, along with the low socio-economic status of northern Adelaide, the number of refugee youth residing there, and the added complexity of treating comorbid MH and AOD problems (comorbidity) prompted this research...
March 24, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28340304/family-members-experiences-of-driving-disruption-after-acquired-brain-injury
#13
Phyllis Liang, Jennifer Fleming, Louise Gustafsson, Janelle Griffin, Jacki Liddle
PRIMARY OBJECTIVE: 1) To explore family members' lived experiences of driving disruption at early and later stages of the recovery continuum following acquired brain injury (ABI). 2) To describe health-related quality of life of family members of individuals with ABI who are experiencing driving disruption. RESEARCH DESIGN: Mixed methods phenomenological research approach. METHODS AND PROCEDURES: Semi-structured interviews and health-related quality of life questionnaires were conducted with 15 family members of individuals with ABI (early group: 1-12 months post-injury, n = 6; later group: >1 year post-injury, n = 9)...
March 24, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28340250/improving-safety-culture-in-hospitals-facilitators-and-barriers-to-implementation-of-systemic-falls-investigative-method-sfim
#14
Aleksandra A Zecevic, Alvin Ho-Ting Li, Charity Ngo, Michelle Halligan, Anita Kothari
Objective: The purpose of this study was to assess the facilitators and barriers to implementation of the Systemic Falls Investigative Method (SFIM) on selected hospital units. Design: A cross-sectional explanatory mixed methods design was used to converge results from a standardized safety culture survey with themes that emerged from interviews and focus groups. Findings were organized by six elements of the Ottawa Model of Research Use framework. Setting: A geriatric rehabilitation unit of an acute care hospital and a neurological unit of a rehabilitation hospital were selected purposefully due to the high frequency of falls...
March 17, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28340131/interobserver-variability-in-histologic-evaluation-of-liver-fibrosis-using-categorical-and-quantitative-scores
#15
Michael Pavlides, Jacqueline Birks, Eve Fryer, David Delaney, Nikita Sarania, Rajarshi Banerjee, Stefan Neubauer, Eleanor Barnes, Kenneth A Fleming, Lai Mun Wang
Objectives: The aim of the study was to investigate the interobserver agreement for categorical and quantitative scores of liver fibrosis. Methods: Sixty-five consecutive biopsy specimens from patients with mixed liver disease etiologies were assessed by three pathologists using the Ishak and nonalcoholic steatohepatitis Clinical Research Network (NASH CRN) scoring systems, and the fibrosis area (collagen proportionate area [CPA]) was estimated by visual inspection (visual-CPA)...
March 15, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28338288/a-comparison-inhibitory-effects-of-cisplatin-and-mnps-peg-cisplatin-on-the-adhesion-capacity-of-bone-metastatic-breast-cancer
#16
Mohammad Javad Mokhtari, Fatemeh Koohpeima, Hadi Mohammadi
To date, high mortality in women due to malignancy breast cancer related to the metastasis to the bone is a significant challenge. Since, magnetic nanoparticles (MNPs) conjugated with the biocompatible polymers was employed for the delivery of some hydrophobic anti-cancer agents, so the main aim of the current research was to assess whether cisplatin-loaded MNPs enhanced the anti-cancer effect of free cisplatin in breast cancer cells.MNPs decorated with PEG were synthesized by an improved co-precipitation technique, and then cisplatin was loaded onto the MNPs via a simple mixing method...
March 24, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28337071/international-standards-for-genomes-transcriptomes-and-metagenomes
#17
Christopher E Mason, Ebrahim Afshinnekoo, Scott Tighe, Shixiu Wu, Shawn Levy
Challenges and biases in preparing, characterizing, and sequencing DNA and RNA can have significant impacts on research in genomics across all kingdoms of life, including experiments in single-cells, RNA profiling, and metagenomics (across multiple genomes). Technical artifacts and contamination can arise at each point of sample manipulation, extraction, sequencing, and analysis. Thus, the measurement and benchmarking of these potential sources of error are of paramount importance as next-generation sequencing (NGS) projects become more global and ubiquitous...
March 17, 2017: Journal of Biomolecular Techniques: JBT
https://www.readbyqxmd.com/read/28336478/an-extended-protocol-for-usability-validation-of-medical-devices-research-design-and-reference-model
#18
Martin Schmettow, Raphaela Schnittker, Jan Maarten Schraagen
This paper proposes and demonstrates an extended protocol for usability validation testing of medical devices. A review of currently used methods for the usability evaluation of medical devices revealed two main shortcomings. Firstly, the lack of methods to closely trace the interaction sequences and derive performance measures. Secondly, a prevailing focus on cross-sectional validation studies, ignoring the issues of learnability and training. The U.S. Federal Drug and Food Administration's recent proposal for a validation testing protocol for medical devices is then extended to address these shortcomings: (1) a novel process measure 'normative path deviations' is introduced that is useful for both quantitative and qualitative usability studies and (2) a longitudinal, completely within-subject study design is presented that assesses learnability, training effects and allows analysis of diversity of users...
March 21, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28336212/impact-of-a-continuing-professional-development-intervention-on-midwifery-academics-awareness-of-cultural-safety
#19
Tania Fleming, Debra K Creedy, Roianne West
BACKGROUND: Cultural safety in higher education learning and teaching environments is paramount to positive educational outcomes for Aboriginal and/or Torres Strait Islander (hereafter called First Peoples) students. There is a lack of research evaluating the impact of continuing professional development on midwifery academics' awareness of cultural safety. AIM: To implement and evaluate a continuing professional development intervention to improve midwifery academics' awareness of cultural safety in supporting First Peoples midwifery students success...
March 20, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28336137/an-ultra-sensitive-method-for-the-analysis-of-perfluorinated-alkyl-acids-in-drinking-water-using-a-column-switching-high-performance-liquid-chromatography-tandem-mass-spectrometry
#20
Kavitha Dasu, Shoji F Nakayama, Mitsuha Yoshikane, Marc A Mills, J Michael Wright, Shelley Ehrlich
In epidemiological research, it has become increasingly important to assess subjects' exposure to different classes of chemicals in multiple environmental media. It is a common practice to aliquot limited volumes of samples into smaller quantities for specific trace level chemical analyses. A novel method was developed for the determination of 14 perfluorinated alkyl acids (PFAAs) in small volumes (10mL) of drinking water using off-line solid phase extraction (SPE) pre-treatment followed by on-line pre-concentration on a WAX column before analysis on column-switching high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS)...
March 6, 2017: Journal of Chromatography. A
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