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https://www.readbyqxmd.com/read/28550814/determination-of-equilibrium-structures-of-bromothymol-blue-revealed-by-using-quantum-chemistry-with-an-aid-of-multivariate-analysis-of-electronic-absorption-spectra
#1
Toru Shimada, Takeshi Hasegawa
The pH dependent chemical structures of bromothymol blue (BTB), which have long been under controversy, are determined by employing a combined technique of multivariate analysis of electronic absorption spectra and quantum chemistry. Principle component analysis (PCA) of the pH dependent spectra apparently reveals that only two chemical species are adequate to fully account for the color changes, with which the spectral decomposition is readily performed by using augmented alternative least-squares (ALS) regression analysis...
May 19, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28550813/a-reliable-sewage-quality-abnormal-event-monitoring-system
#2
Tianling Li, Melissa Winnel, Hao Lin, Jared Panther, Chang Liu, Roger O'Halloran, Kewen Wang, Taicheng An, Po Keung Wong, Shanqing Zhang, Huijun Zhao
With closing water loop through purified recycled water, wastewater becomes a part of source water, requiring reliable wastewater quality monitoring system (WQMS) to manage wastewater source and mitigate potential health risks. However, the development of reliable WQMS is fatally constrained by severe contamination and biofouling of sensors due to the hostile analytical environment of wastewaters, especially raw sewages, that challenges the limit of existing sensing technologies. In this work, we report a technological solution to enable the development of WQMS for real-time abnormal event detection with high reliability and practicality...
May 20, 2017: Water Research
https://www.readbyqxmd.com/read/28550698/boomr-better-coordinated-cross-sectoral-medication-reconciliation-for%C3%A2-residential-care
#3
Vincent Vuong, Denis O'Donnell, Hrishikesh Navare, Debra Merrill, Michal Racki, Sheila Burton, Lori Anderson, Carla Beaton
There is evidence that medication errors often arise during the transition of residents from acute care to long-term care (LTC) homes due to lapses in communication and documentation. Better Coordinated Cross-Sectoral Medication Reconciliation (BOOMR) is an integrated practice change improving medication safety during patient transitions through the health system. Our Medication Reconciliation (MedRec) redesign improved patient engagement using "the patient's story," increased quality of information, workflow efficiency and reduced unnecessary medications...
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/28550029/pulmonary-function-changes-after-radiotherapy-for-lung-or-esophageal-cancer-a-systematic-review-focusing-on-dose-volume-parameters
#4
Anne G H Niezink, Renske A de Jong, Christina T Muijs, Johannes A Langendijk, Joachim Widder
BACKGROUND: Despite technical developments in treatment delivery, radiation-induced lung toxicity (RILT) remains a crucial problem in thoracic radiotherapy. Clinically based RILT scores have their limitations, and more objective measures such as pulmonary functions tests (PFTs) might help to improve treatment strategies. PURPOSE: To summarize the available evidence about the effect of dose to the lung in thoracic radiotherapy on forced expiratory volume in one second (FEV1) and diffusion capacity (DLCO) in patients with lung and esophageal cancer treated with curative intent...
May 26, 2017: Oncologist
https://www.readbyqxmd.com/read/28550022/longitudinal-assessment-of-brain-derived-neurotrophic-factor-in-sardinian-psychotic-patients-labsp-a-protocol-for-a-prospective-observational-study
#5
Diego Primavera, Mirko Manchia, Luca Deriu, Massimo Tusconi, Roberto Collu, Maria Scherma, Paola Fadda, Walter Fratta, Bernardo Carpiniello
INTRODUCTION: Brain-derived neurotrophic factor (BDNF) plays a crucial role in neurodevelopment, synaptic plasticity and neuronal function and survival. Serum and plasma BDNF levels are moderately, but consistently, decreased in patients with schizophrenia (SCZ) compared with healthy controls. There is a lack of knowledge, however, on the temporal manifestation of this decline. Clinical, illness course and treatment factors might influence the variation of BDNF serum levels in patients with psychosis...
May 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/28549980/trends-in-malpractice-claims-for-obstetric-and-gynecologic-procedures-2005-2014
#6
Laura M Glaser, Farah A Alvi, Magdy P Milad
BACKGROUND: Interest in medical malpractice and areas of medico-legal vulnerability for practicing obstetricians and gynecologists has grown substantially, and many providers report changing surgical practice out of fear of litigation. Furthermore, education on medical malpractice and risk management is lacking for obstetrics and gynecology trainees. Recent obstetric and gynecologic malpractice claims data is lacking. We report on recent trends in malpractice claims for obstetrics and gynecology procedures, and compare these trends to those of other medical specialties...
May 23, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28549929/pragmatic-trials-and-real-world-evidence-an-introduction-to-the-series
#7
Mira Zuidgeest, Iris Goetz, Rolf Groenwold, Elaine Irving, Ghislaine van Thiel, Diederick E Grobbee
This is the introductory paper in a series of 8 papers (see box). In this series we integrate the theoretical design options with the practice of conducting pragmatic trials. For most new market-approved treatments the clinical evidence is insufficient to fully guide physicians and policy makers in choosing the optimal treatment for their patients. Pragmatic trials can fill this gap, by providing evidence on the relative effectiveness of a treatment strategy in routine clinical practice, already in an early phase of development, while maintaining the strength of randomized controlled trials...
May 23, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28549852/circular-dichroism-analysis-of-the-calicheamicin-dna-interaction-revisited
#8
Gloria Proni, Kristi Tami, Nina Berova, George A Ellestad
Calicheamicin, γ1(I), is a remarkable DNA binding-cleaving, enediyne-containing, natural product that exhibits potent antitumor activity. In this study, we used electronic circular dichroism spectroscopy to monitor potential drug-induced DNA conformational changes and DNA induced conformational changes in the calicheamicin aglycone. Three DNA dodecamer sequences were examined: one containing a primary TCCT binding/cleavage site and two dodecamers containing less prominent CTCT and TCTC sites. The binding was monitored by taking advantage of the drug's unique negative exciton couplet (-313nm/+275nm) in phosphate buffer/ethanol 10%...
May 13, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28549750/shared-decision-making-in-brazil-concrete-efforts-to-empowering-patient-s-voice
#9
Mirhelen Mendes de Abreu, Joao Pedro Simao de Mello, Lilah Ferreira F Ribeiro, Luiza Andrade Mussi, Mariana Luiza L Borges, Maurício Petroli, Nycholas da Costa Tavares, Rafael da Cunha Cancela, Sabrina Fausto de Lima
Patient involvement in healthcare decisions has grown in Brazil at three different levels: 1) the macro level, which includes the patient actively influencing legislation and regulation of medical care as well as political changes in the process of care itself; 2) the meso level, which includes institutions that aim to improve information, empowerment and counseling to patients, and 3) the micro level, which focuses on the actual decision-making process that takes place within patient-physician encounter. In Brazil, the macro and meso levels are stronger than the micro one...
May 23, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28549568/using-visual-analytics-for-presenting-comparative-information-on-new-drugs
#10
Jean-Baptiste Lamy, Hélène Berthelot, Madeleine Favre, Adrien Ugon, Catherine Duclos, Alain Venot
OBJECTIVE: When a new drug is marketed, physicians must decide whether they will consider it for their future practice. However, information about new drugs can be biased or hard to find. In this work, our objective was to study whether visual analytics could be used for comparing drug properties such as contraindications and adverse effects, and whether this visual comparison can help physicians to forge their own well-founded opinions about a new drug. MATERIALS AND METHODS: First, an ontology for comparative drug information was designed, based on the expectations expressed during focus groups comprised of physicians...
May 23, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28549460/learning-to-use-electronic-health-records-can-we-stay-patient-centered-a-pre-post-intervention-study-with-family-medicine-residents
#11
Cédric Lanier, Melissa Dominicé Dao, Patricia Hudelson, Bernard Cerutti, Noëlle Junod Perron
BACKGROUND: The Electronic Health Record (EHR) is now widely used in clinical encounters. Because its use can negatively impact the physician-patient relationship, several recommendations on the "patient-centered" use of the EHR have been published. However, the impact of training to improve EHR use during clinical encounters is not well known. The aim of this study was to assess the impact of training on residents' EHR-related communication skills and explore whether they varied according to the content of the consultation...
May 26, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28549399/a-systematic-review-investigating-psychosocial-aspects-of-egg-sharing-in-the-united-kingdom-and-their-potential-effects-on-egg-donation-numbers
#12
Timothy Bracewell-Milnes, Srdjan Saso, Hossam Abdalla, Meen-Yau Thum
This review aims to provide an up-to-date knowledge of the psychosocial aspects of egg donation from the perspectives of the egg share donor and their recipient. It explores the motives, experiences and attitudes of egg sharers and their views towards donor anonymity and disclosure. Conclusions are made on how these findings can guide clinical practice and improve egg sharing numbers. A systematic search of peer-reviewed journals of four computerized databases was undertaken. Eleven studies were included in the review...
May 26, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28549049/institution-of-a-preoperative-stoma-education-group-class-decreases-rate-of-peristomal-complications-in-new-stoma-patients
#13
Audrey L Stokes, Shelly Tice, Suzi Follett, Diane Paskey, Lini Abraham, Cheryl Bealer, Holly Keister, Walter Koltun, Frances J Puleo
PURPOSE: The purpose of this study was to compare selected postoperative complications (including stomal and peristomal complications), hospital length of stay, and readmission rates in a group of patients who attended a preoperative educational intervention to a retrospective group of patients who did not receive the intervention. DESIGN: Retrospective, comparison cohort study. SUBJECTS AND SETTING: The intervention group comprised 124 patients who attended an educational session for persons with fecal ostomies at a single tertiary care center in the Northeastern United States...
May 25, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28549033/estrogen-receptor-progesterone-receptor-and-human-epidermal-growth-factor-receptor-2-testing-in-breast-cancer-assessing-the-value-of-repeated-centralized-testing-in-excision-specimens
#14
Nosaibah Hariri, Farnaz Hasteh, Vighnesh Walavalkar, Andres A Roma, Oluwole Fadare
At some tertiary breast care centers, where many patients are referred from other institutions, it is routine to repeat testing for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2/neu) in excision specimens if these tests were performed on the preceding biopsy at the referring facility. The goal of this study is to assess the value of this practice. We documented results from ER, PR, and HER2 testing in 541 consecutive invasive breast cancers excised over a 2...
May 25, 2017: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/28549015/early-oral-feeding-following-mckeown-minimally-invasive-esophagectomy-an-open-label-randomized-controlled-noninferiority-trial
#15
Hai-Bo Sun, Yin Li, Xian-Ben Liu, Rui-Xiang Zhang, Zong-Fei Wang, Toni Lerut, Chia-Chuan Liu, Alfonso Fiorelli, Yin-Kai Chao, Daniela Molena, Robert J Cerfolio, Soji Ozawa, Andrew C Chang
OBJECTIVE: Our objective was to evaluate the impact of early oral feeding (EOF) on postoperative cardiac, respiratory, and gastrointestinal (CRG) complications after McKeown minimally invasive esophagectomy for esophageal cancer. SUMMARY BACKGROUND DATA: Nil-by-mouth with enteral tube feeding is routinely practiced after esophagectomy. METHODS: Patients were randomly allocated to receive oral feeding on the first postoperative day (EOF group) or late oral feeding (LOF group) 7 days after surgery...
May 25, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28548991/protein-nutrition-and-exercise-survival-kit-for-critically-ill
#16
Peter J M Weijs
PURPOSE OF REVIEW: Protein delivery as well as exercise of critically ill in clinical practice is still a highly debated issue. Here we discuss only the most recent updates in the literature concerning protein nutrition and exercise of the critically ill. RECENT FINDINGS: By lack of randomized controlled trial (RCTs) in protein nutrition we discuss four post-hoc analyses of nutrition studies and one experimental study in mice. Studies mainly confirm some insights that protein and energy effects are separate and that the trajectory of the patient in the ICU might change these effects...
May 25, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/28548893/dynamic-decision-making-learning-processes-and-new-research-directions
#17
Cleotilde Gonzalez, Pegah Fakhari, Jerome Busemeyer
OBJECTIVE: The aim of this manuscript is to provide a review of contemporary research and applications on dynamic decision making (DDM). BACKGROUND: Since early DDM studies, there has been little systematic progress in understanding decision making in complex, dynamic systems. Our review contributes to better understanding of decision making processes in dynamic tasks. METHOD: We discuss new research directions in DDM to highlight the value of simplification in the study of complex decision processes, divided into experimental and theoretical/computational approaches, and focus on problems involving control tasks and search-and-choice tasks...
May 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28548555/transforming-students-attitudes-and-anxieties-toward-death-and-loss
#18
Cara L Wallace, Harriet L Cohen, David A Jenkins
This study examines the impact of a death and dying course on 39 undergraduate students' attitudes and anxieties about death. Authors outline key aspects of the curriculum used in the course and discuss how the approach lends itself to a transformative learning experience related to death and loss, preparing students who will face clients with a variety of needs in these areas across practice settings. The majority of students ( n = 34) experienced a decrease in death avoidance, fear of death, and overall death anxiety...
January 1, 2017: Omega
https://www.readbyqxmd.com/read/28548205/reflections-on-klein-s-radical-notion-of-phantasy-and-its-implications-for-analytic-practice
#19
Rachel B Blass
Analysts may incorporate many of Melanie Klein's important contributions (e.g., on preoedipal dynamics, envy, and projective identification) without transforming their basic analytic approach. In this paper I argue that adopting the Kleinian notion of unconscious phantasy is transformative. While it is grounded in Freud's thinking and draws out something essential to his work, this notion of phantasy introduces a radical change that defines Kleinian thinking and practice and significantly impacts the analyst's basic clinical approach...
May 26, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/28548174/the-mechanism-change-by-switching-the-reactants-from-water-to-hydroxyl-ions-for-electrocatalytic-water-oxidation-a-case-study-of-copper-oxide-microspheres
#20
Xiaoqiang Du, Jingwei Huang, Yong Ding
Developing noble metal-free water oxidation catalysts is essential for many energy conversion/storage processes (e.g., water splitting). Herein, we report a facile synthesis of CuO microspheres composed of ultrathin, single-crystal-like nanosheets via a simple solution method. The as-obtained CuO microspheres can serve as an active and stable water oxidation catalyst under electrochemical reaction conditions, owing to their unique structural features. In electrochemical water oxidation, this catalyst affords a current density of 10 mA cm(-2) (a value related to practical relevance) at an overpotential of ∼0...
May 26, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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