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https://www.readbyqxmd.com/read/27916665/task-modulations-and-clinical-manifestations-in-the-brain-functional-connectome-in-1615-fmri-datasets
#1
Tobias Kaufmann, Dag Alnæs, Christine Lycke Brandt, Nhat Trung Doan, Karolina Kauppi, Francesco Bettella, Trine V Lagerberg, Akiah O Berg, Srdjan Djurovic, Ingrid Agartz, Ingrid S Melle, Torill Ueland, Ole A Andreassen, Lars T Westlye
OBJECTIVE: An abundance of experimental studies have motivated a range of models concerning the cognitive underpinnings of severe mental disorders, yet the conception that cognitive and brain dysfunction is confined to specific cognitive domains and contexts has limited ecological validity. Schizophrenia and bipolar spectrum disorders have been conceptualized as disorders of brain connectivity; yet little is known about the pervasiveness across cognitive tasks. METHOD: To address this outstanding issue of context specificity, we estimated functional network connectivity from fMRI data obtained during five cognitive tasks (0-back, 2-back, go/no-go, recognition of positive faces, negative faces) in 90 patients with schizophrenia, 97 patients with bipolar spectrum disorder, and 136 healthy controls, including 1615 fMRI datasets in total...
December 1, 2016: NeuroImage
https://www.readbyqxmd.com/read/27913280/neuropsychological-functioning-and-chronic-methadone-use-a-systematic-review-and-meta-analysis
#2
REVIEW
A Baldacchino, M Armanyous, D J K Balfour, G Humphris, K Matthews
INTRODUCTION: There is a presumption that neurocognition is commonly impaired in chronic methadone exposed individuals (CM) when compared with healthy controls (HP). Additionally, it remains unclear if short term (<1year) abstinence (AP) is associated with an altered cognitive profile when compared with CM. METHOD: A random effect model approach was used on data assembled into the Comprehensive Meta-Analysis programme. Cohen's d effect sizes and a significance levels of p<0...
November 29, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27913159/assessing-functional-performance-using-computer-based-simulations-of-everyday-activities
#3
Sara J Czaja, David A Loewenstein, Chin Chin Lee, Shih Hua Fu, Philip D Harvey
Current functional capacity (FC) measures for patients with schizophrenia typically involve informant assessments or are in paper and pencil format, requiring in-person administration by a skilled assessor. This approach presents logistic problems and limits the possibilities for remote assessment, an important issue for these patients. This study evaluated the feasibility of using a computer-based assessment battery, including simulations of everyday activities. The battery was compared to in-person standard assessments of cognition and FC with respect to baseline convergence and sensitivity to group differences...
November 29, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27912992/brain-tumors-and-metastases
#4
REVIEW
Mary M Vargo
Patients with brain tumor exhibit wide-ranging prognoses and functional implications of their disease and treatments. In general, the supportive care needs of patients with brain tumor, including disabling effects, have been recognized to be high. This review (1) briefly summarizes brain tumor types, treatments, and prognostic information for the rehabilitation clinician; (2) reviews evidence for rehabilitation, including acute inpatient rehabilitation and cognitive rehabilitation, and the approaches to selected common symptom and medical management issues; and (3) examines emerging data about survivorship, such as employment, community integration, and fitness...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27912947/exploratory-outcome-assessment-of-qigong-tai-chi-easy-on-breast-cancer-survivors
#5
Linda K Larkey, Denise J Roe, Lisa Smith, Denise Millstine
OBJECTIVE: Breast cancer survivors (BCSs) experience symptoms affecting overall quality of life (QOL), often for a prolonged period post-treatment. Meditative Movement (MM), including Qigong and Tai Chi Easy (QG/TCE), has demonstrated benefit for improving QOL issues such as fatigue and sleep, but there is limited evidence of its impact on cognitive function, overall physical activity, and body weight for BCSs. DESIGN: This double-blind, randomized controlled pilot study with 87 female BCSs explored effects of QG/TCE on mental and physical QOL (Medical Outcomes Survey, Short Form), cognitive function (Functional Assessment of Cancer Therapy-Cognitive Function and two cognitive performance tests from the WAIS III), overall levels of physical activity (PA)(Brief Physical Activity Questionnaire) and body mass index (BMI)...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27909415/imagining-change-an-integrative-approach-toward-explaining-the-motivational-role-of-mental-imagery-in-pro-environmental-behavior
#6
Christine Boomsma, Sabine Pahl, Jackie Andrade
Climate change and other long-term environmental issues are often perceived as abstract and difficult to imagine. The images a person associates with environmental change, i.e., a person's environmental mental images, can be influenced by the visual information they come across in the public domain. This paper reviews the literature on this topic across social, environmental, and cognitive psychology, and the wider social sciences; thereby responding to a call for more critical investigations into people's responses to visual information...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27909095/dynamic-shifts-in-large-scale-brain-network-balance-as-a-function-of-arousal
#7
Christina B Young, Gal Raz, Daphne Everaerd, Christian F Beckmann, Indira Tendolkar, Talma Hendler, Guillén Fernández, Erno J Hermans
: The ability to temporarily prioritize rapid and vigilant reactions over slower higher-order cognitive functions is essential for adaptive responding to threat. This reprioritization is believed to reflect shifts in resource allocation between large-scale brain networks that support these cognitive functions, including the salience and executive control networks. How changes in communication within and between such networks dynamically unfold as a function of threat-related arousal, however, remains unknown...
December 1, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27908294/outcomes-of-notifications-to-health-practitioner-boards-a-retrospective-cohort-study
#8
Matthew J Spittal, David M Studdert, Ron Paterson, Marie M Bismark
BACKGROUND: Medical boards and other practitioner boards aim to protect the public from unsafe practice. Previous research has examined disciplinary actions against doctors, but other professions (e.g., nurses and midwives, dentists, psychologists, pharmacists) remain understudied. We sought to describe the outcomes of notifications of concern regarding the health, performance, and conduct of health practitioners from ten professions in Australia and to identify factors associated with the imposition of restrictive actions...
December 2, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27904818/the-government-s-role-in-regulating-coordinating-and-standardizing-the-response-to-alzheimer-s-disease-anticipated-international-cooperation-in-the-area-of-intractable-and-rare-diseases
#9
REVIEW
Qi Tang, Peipei Song, Lingzhong Xu
The World Health Organization (WHO) has emphasized that aging of the population is inextricably linked to many other global public health issues, such as universal health coverage, non-communicable diseases, and disability. However, Alzheimer's Disease International (ADI) estimates that 46.8 million elderly people worldwide were living with dementia in 2015. Alzheimer's disease (AD), the most common form of dementia, is one of the most common neurodegenerative diseases and is the main cause of cognitive impairment...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27904636/effect-of-cognitive-behavioral-stress-management-program-on-psychosomatic-patients-quality-of-life
#10
Zahra Ghazavi, Esmat Rahimi, Mohsen Yazdani, Hamid Afshar
BACKGROUND: Level of stress and its management affects the dimensions of psychosomatic patients' quality of life (QoL), which is an important psychological issue. The present study aimed to investigate the effect of cognitive behavioral stress management program on psychosomatic patients' QoL. In cognitive behavioral method, patients discover thought and behavioral mistakes and recover them. The criterion to evaluate the success of the present study was measurement of the patients' QoL and its notable improvement after intervention...
September 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/27903936/operationalising-cognitive-fatigability-in-multiple-sclerosis-a-gordian-knot-that-can-be-cut
#11
Anthony Mark Harrison, Roshan das Nair, Rona Moss-Morris
BACKGROUND: Researchers have attempted to operationalise objective measures of cognitive fatigability in multiple sclerosis (MS) to overcome the perceived subjectivity of patient-reported outcomes of fatigue (PROs). Measures of cognitive fatigability examine decrements in performance during sustained neurocognitive tasks. OBJECTIVE: This personal viewpoint briefly summarises available evidence for measures of cognitive fatigability in MS and considers their overall utility...
November 30, 2016: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/27903322/non-use-of-day-care-services-for-dementia-in-singapore-a-dilemma-for-caregivers
#12
Shan Huang, Konstadina Griva, Christina A Bryant, Philip Yap
BACKGROUND: Day care services for patients with dementia (PWD) are generally under-utilized worldwide despite evidence of positive outcomes, such as improved behavioral, psychological, and cognitive functioning for patients, and reduced caregiver burden. This study sought to gain an in-depth understanding of the reasons for non-utilization of day care services in Singapore using qualitative methodology. METHODS: A purposive sample of 16 caregivers of PWD who had never attended day care services participated in semi-structured interviews...
December 1, 2016: International Psychogeriatrics
https://www.readbyqxmd.com/read/27902446/science-signaling-podcast-for-15-november-2016-a-new-type-of-kinase-inhibitor
#13
Hagit Eldar-Finkelman, Annalisa M VanHook
This Podcast features an interview with Hagit Eldar-Finkelman, author of a Research Article that appears in the 15 November 2016 issue of Science Signaling, about a newly developed inhibitor of glycogen synthase kinase 3 (GSK-3). GSK-3 participates in several signaling networks and has been implicated in various pathologies, including neurodegenerative diseases, cognitive impairments, and cancer. Licht-Murava et al developed L807mts, a substrate-competitive peptide inhibitor that blocks GSK-3 activity through an unusual mechanism...
November 15, 2016: Science Signaling
https://www.readbyqxmd.com/read/27899724/working-memory-capacity-and-fluid-intelligence-maintenance-and-disengagement
#14
Zach Shipstead, Tyler L Harrison, Randall W Engle
Working memory capacity and fluid intelligence have been demonstrated to be strongly correlated traits. Typically, high working memory capacity is believed to facilitate reasoning through accurate maintenance of relevant information. In this article, we present a proposal reframing this issue, such that tests of working memory capacity and fluid intelligence are seen as measuring complementary processes that facilitate complex cognition. Respectively, these are the ability to maintain access to critical information and the ability to disengage from or block outdated information...
November 2016: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/27897669/domain-general-stroop-performance-and-hemispheric-asymmetries-a-resting-state-eeg-study
#15
Ettore Ambrosini, Antonino Vallesi
The ability to suppress irrelevant information while executing a task or interference resistance is a function of pFC that is critical for successful goal-directed human behavior. In the study of interference resistance and, more generally, executive functions, two key questions are still open: Does pFC contribute to cognitive control abilities through lateralized but domain-general mechanisms or through hemispheric specialization of domain-specific processes? And what are the underlying causes of interindividual differences in executive control performance? To shed light on these issues, here we employed an interindividual difference approach to investigate whether participants' hemispheric asymmetry in resting-state electrophysiological brain dynamics may reflect their variability in domain-general interference resistance...
November 29, 2016: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/27895563/the-attentional-dependence-of-emotion-cognition-is-variable-with-the-competing-task
#16
Cheng Chen, Kaibin Jin, Yehua Li, Hongmei Yan
The relationship between emotion and attention has fascinated researchers for decades. Many previous studies have used eye-tracking, ERP, MEG, and fMRI to explore this issue but have reached different conclusions: some researchers hold that emotion cognition is an automatic process and independent of attention, while some others believed that emotion cognition is modulated by attentional resources and is a type of controlled processing. The present research aimed to investigate this controversy, and we hypothesized that the attentional dependence of emotion cognition is variable with the competing task...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27895554/systemic-radical-scavenger-treatment-of-a-mouse-model-of-rett-syndrome-merits-and-limitations-of-the-vitamin-e-derivative-trolox
#17
Oliwia A Janc, Marc A Hüser, Katharina Dietrich, Belinda Kempkes, Christiane Menzfeld, Swen Hülsmann, Michael Müller
Rett syndrome (RTT) is a severe neurodevelopmental disorder typically arising from spontaneous mutations in the X-chromosomal methyl-CpG binding protein 2 (MECP2) gene. The almost exclusively female Rett patients show an apparently normal development during their first 6-18 months of life. Subsequently, cognitive- and motor-impairment, hand stereotypies, loss of learned skills, epilepsy and irregular breathing manifest. Early mitochondrial impairment and oxidative challenge are considered to facilitate disease progression...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27895063/association-of-eating-behaviours-with-diurnal-preference-and-rotating-shift-work-in-japanese-female-nurses-a-cross-sectional-study
#18
Takahiro Yoshizaki, Yukari Kawano, Osamu Noguchi, Junko Onishi, Reiko Teramoto, Ayaka Sunami, Yuri Yokoyama, Yuki Tada, Azumi Hida, Fumiharu Togo
OBJECTIVES: Our study examines differences in eating behaviour between day workers and rotating shift workers, and considers whether diurnal preference could explain the differences. METHODS: Japanese female nurses were studied (39 day workers and 123 rotating shift workers, aged 21-63 years) using self-administered questionnaires. The questionnaires assessed eating behaviours, diurnal preference and demographic characteristics. The questionnaire in the Guidelines for the management of obesity disease issued by the Japan Society for the Study of Obesity was used to obtain scores for the levels of obesity-related eating behaviours, including cognition of constitution, motivation for eating, eating as a diversion, feeling of satiety, eating style, meal contents and temporal eating patterns...
November 28, 2016: BMJ Open
https://www.readbyqxmd.com/read/27894727/factors-associated-with-gait-speed-recovery-after-total-knee-arthroplasty-a-longitudinal-study
#19
Yong-Hao Pua, Felicia Jie-Ting Seah, Ross Allan Clark, Cheryl Lian-Li Poon, John Wei-Ming Tan, Hwei-Chi Chong
OBJECTIVES: Gait speed limitations can remain significant issues after a total knee arthroplasty (TKA) but their associated factors are not well understood. This study aimed to identify the factors associated with acute gait speed recovery post-TKA. METHODS: We performed a prospective longitudinal study of 1765 patients who underwent primary TKA between July 2013 and July 2015. At 4, 8, 12, and 16 weeks postsurgery, fast gait speed was measured. The factors associated with gait speed over time since TKA were identified using multivariable generalized least squares modeling...
November 1, 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/27894219/exposure-to-culturally-sensitive-sexual-health-information-and-impact-on-health-literacy-a-qualitative-study-among-newly-arrived-refugee-women-in-sweden
#20
Pia Svensson, Katarina Carlzén, Anette Agardh
In Sweden, migrants have poorer sexual and reproductive health compared to the general population. Health literacy, in the form of the cognitive and social skills enabling access to health promoting activities, is often poorer among migrants, partly due to language and cultural barriers. Culturally sensitive health education provides a strategy for enhancing health literacy. Since 2012, specially trained civic and health communicators have provided sexual and reproductive health and rights information to newly arrived refugees in Skåne, Sweden...
November 29, 2016: Culture, Health & Sexuality
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