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Swetha Paluru, Thomas M Ulbright, Mahul Amin, Rodolfo Montironi, Jonathan I Epstein
Sertoliform cystadenoma of the rete testis (SCRT) is rare with only 9 cases reported to date in the literature, none with follow-up. Four large genitourinary pathology consult services were searched. We identified 15 cases of SCRT. Men were 21 to 84 years old (mean, 46 y) and had testicular discomfort or mass. Other findings were seminoma (n=1), spermatocele (n=2), hydrocele (n=1), varicocele (n=1), and scrotal hematoma (n=1). Eight had preoperative serum tumor markers, which were normal. Tumors ranged from 0...
December 7, 2017: American Journal of Surgical Pathology
Xiangshan Fan, Ling Lin, Jianjun Wang, Yu Wang, Anning Feng, Ling Nie, Hongyan Wu, Fanqing Meng, Haodong Xu
BACKGROUND: Pulmonary sclerosing pneumocytoma (PSP) typically presents solitary and peripheral mass, while only rarely cases display unusual multiple lesions. We reported a extremely rare case of PSP with diffusely-scattered nodules in the right lung. CASE PRESENTATION: Diffusely round-shaped nodular shadows in the right lung were found by CT scan in a 31-year-old Chinese woman. The patient undergone the right pneumnectomy. Grossly, numerous small nodules, up to 2...
December 13, 2017: Cancer Biology & Therapy
Eugenia Peresypkina, Claudia Heindl, Eric Mädl, Helena Brake, Alexander Virovets, Manfred Scheer
Pentaphosphaferrocene [Cp*Fe(η5-P5)] (1a) represents an excellent building block for the template-directed synthesis of spherical supramolecules. Herein, the self-assembly of 1a with Cu(I) and Cu(II) halides in the presence of the template complexes [FeCp2][PF6], [CoCp2][PF6] and [CoCp2] is reported testifying the redox behavior of the formed supramolecules. The oxidation or reduction capacity of these labile complexes does not inhibit their template impact and, for the first time, the cationic metallocene [CoCp2]+ is enclosed in unprecedented anionic organometallic hosts...
December 13, 2017: Chemistry: a European Journal
Holger H H Erb, Fabian Guggenberger, Frédéric R Santer, Zoran Culig
Pro- and anti-inflammatory cytokines may influence proliferation, migration, invasion and other cellular events of prostate cancer (PCa) cells. The hyaluronan receptor CD44, which is regulated by Interleukin (IL)-4, is a prostate basal cell marker. CD44high /CD49bhigh expressing cells have been demonstrated to have tumor-initiating characteristics. Here, we aimed to analyze the effects of long-term IL-4 treatment on CD44/CD49b expression, migration, proliferation and clonogenic potential of basal-like PCa cells...
December 13, 2017: Journal of Cellular Biochemistry
Guan Xu, Jing Yuan, Xiaotao Li, Jian Su
A flexible reconstruction method, which is based on the line re-projection errors of the laser plane, is presented for the profile recovery. The bi-cuboid references are designed to cover the large view-field of the camera. The local intrinsic and extrinsic parameter matrices of the camera are initially contributed by the RQ decomposition. Then the balance model is demonstrated to obtain the global parameter matrices in view of the refined projection in the camera coordinate system. The flexible laser plane is solved by the Plücker matrices of the projection laser lines that are generated from the homographies of the cubical references and the global parameter matrices...
November 27, 2017: Optics Express
Luvena L Ong, Nikita Hanikel, Omar K Yaghi, Casey Grun, Maximilian T Strauss, Patrick Bron, Josephine Lai-Kee-Him, Florian Schueder, Bei Wang, Pengfei Wang, Jocelyn Y Kishi, Cameron Myhrvold, Allen Zhu, Ralf Jungmann, Gaetan Bellot, Yonggang Ke, Peng Yin
Nucleic acids (DNA and RNA) are widely used to construct nanometre-scale structures with ever increasing complexity, with possible application in fields such as structural biology, biophysics, synthetic biology and photonics. The nanostructures are formed through one-pot self-assembly, with early kilodalton-scale examples containing typically tens of unique DNA strands. The introduction of DNA origami, which uses many staple strands to fold one long scaffold strand into a desired structure, has provided access to megadalton-scale nanostructures that contain hundreds of unique DNA strands...
December 6, 2017: Nature
Min Bao, Jing Xie, Aigars Piruska, Wilhelm T S Huck
Geometrical cues have been shown to alter gene expression and differentiation on 2D substrates. However, little is known about how geometrical cues affect cell function in 3D. One major reason for this lack of understanding is rooted in the difficulties of controlling cell geometry in a complex 3D setting and for long periods of culture. Here, we present a robust method to control cell volume and shape of individual human mesenchymal stem cells (hMSCs) inside 3D microniches with a range of different geometries (e...
December 6, 2017: Nature Communications
Á González García, H H Wensink, H N W Lekkerkerker, R Tuinier
Entropy-driven equilibrium phase behaviour of hard particle dispersions can be understood from excluded volume arguments only. While monodisperse hard spheres only exhibit a fluid-solid phase transition, anisotropic hard particles such as rods, discs, cuboids or boards exhibit various multi-phase equilibria. Ordering of such anisotropic particles increases the free volume entropy by reducing the excluded volume between them. The addition of depletants gives rise to an entropic patchiness represented by orientation-dependent attractions resulting in non-trivial phase behaviour...
December 6, 2017: Scientific Reports
Kazuki Yoshioka, Aika Ishikawa, Makoto Sugiyama, Jun Nagasao, Motohiro Kikuchi
The present report describes a newborn calf with spina bifida that presented with a giant mass of the lumbar region, as well as subsequent gross, histological, and immunohistochemical examinations. A malformed Japanese black calf (estimated weight = 20 kg) was euthanized immediately after birth. A gross evaluation revealed a giant mass (approximately 60 cm × 30 cm × 15 cm) covered by the hair coat in the lumbar region and connected with the hair coat of the trunk. The mass surface was divided by a deep polygonal groove and externally resembled a lobulated kidney...
2017: Okajimas Folia Anatomica Japonica
Hilmarie Muniz-Talavera, Jennifer V Schmidt
During the first postnatal week of mouse development, radial glial cells lining the ventricles of the brain differentiate into ependymal cells, undergoing a morphological change from pseudostratified cuboidal cells to a flattened monolayer. Concomitant with this change, multiple motile cilia are generated and aligned on each nascent ependymal cell. Proper ependymal cell development is crucial to forming the brain tissue:CSF barrier, and to the establishment of ciliary CSF flow, but the mechanisms that regulate this differentiation event are poorly understood...
2017: PloS One
Santosh Rai, Sonali Prabhu, Sharada Rai, Murali Nirupama, Deepa Sa Adiga, Ashvini Kumar, Shrijeet Chakraborti
Introduction: Solid Pseudopapillary Neoplasms (SPN) are uncommon pancreatic tumours and are slow growing with uncertain malignant potential, showing female preponderance. Postoperative prognosis is good and metastasis is rare. Aim: To summarise the imaging and pathological features of seven cases of SPN in three years period, from January 2013 to January 2016. Materials and Methods: In this retrospective study the imaging features of seven cases on triphasic multidetector Computed Tomogram (CT), a 16-slice scanner, were reviewed along with CT-guided Fine Needle Aspiration Cytology (FNAC) and histopathological examination...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
Amol Saxena, Deann Hofer
This report presents an innovative surgical technique for the correction of cuboid-metatarsal subluxation at the level of the lateral Lisfranc joint. This stabilization technique reinforces the dorsal fourth tarsometatarsal ligament by incorporating sutures and anchors, establishing a more stable joint. The data from 5 female patients undergoing stabilization using a suture anchor construct were reviewed. All 5 patients were able to resume their activities, including the adolescent athletes. Anatomic reconstruction of the dorsal fourth tarsometatarsal ligament complex can lead to full mechanical and functional stability, which ultimately allows for a return to activity, even in highly demanding sports and athletes...
December 1, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Yawen Li, Yunhong Dong, Xiaran Miao, Yulin Ren, Beilin Zhang, Pinpin Wang, Yang Yu, Bin Li, Lyle Isaacs, Liping Cao
Two kinds of shape-controllable and fluorescent supramolecular organic frameworks (cuboid or spheroid) are constructed hierarchically from CB[8] and tetraphenylethylene derivatives through host-guest interaction in water. These two fluorescent SOFs exhibit intriguing and varied photophysical properties, including large red-shifts (up to 82 nm) and stimuli-responsive behavior to competitive guest by binding with CB[8], whose turn-on fluorescence is applied in cellular imaging.
November 30, 2017: Angewandte Chemie
Xin Gu, Minyu Cheng, Guillermo A Herrera
Primary carcinoid tumor of the kidney is uncommon. Only limited morphologic studies have been reported in the literature. In general, renal carcinoid tumor reveals typical morphological features as present in carcinoid tumors in the other organs, i.e. growing as trabeculae intermixed with nests of monotonous cuboidal cells that show "salt and pepper" nuclear appearance. As reported in other organs, different morphological expressions may also present in renal carcinoid tumors, such as papillary, pseudoglandular or solid growth patterns and clear/eosinophilic cytoplasmic changes...
December 1, 2017: Ultrastructural Pathology
Hang Wei, Zhonghong Xia, Dingguo Xia
The exploration of anode material of lithium-ion batteries (LIBs) is still a great challenge because of its low electrical conductivity and poor durability. Transition metal oxide is proposed as a potential alternative, while the dimension and structure greatly affect its electrochemical properties. In this study, MnO/Mn2SiO4@C cuboid was prepared via polymerization-pyrolysis process. Larger MnCO3 precursor particles melted into monolithic carbon framework and formed smaller nanoparticles due to the inducing effect of Si element in phthalocyanino silicon (SiPc), thus the MnO/Mn2SiO4@C cuboids were obtained...
December 1, 2017: ACS Applied Materials & Interfaces
Rizwan Ali, Nosaibah Samman, Hajar Al Zahrani, Atef Nehdi, Sabhi Rahman, Abdul Latif Khan, Mohamed Al Balwi, Lolwah Abdullah Alriyees, Manal Alzaid, Ahmed Al Askar, Mohamed Boudjelal
BACKGROUND: Breast cancer is one of the most common cancer and a leading cause of death in women. Up to date the most commonly used breast cancer cell lines are originating from Caucasians or Afro-Americans but rarely cells are being derived from other ethnic groups. Here we describe for the first time the establishment of a naturally transformed breast cancer cell line, KAIMRC1 from an Arab woman of age 62 suffering from stage IIB breast cancer (T2N1M0). Moreover, we have characterized these cells for the biological and molecular markers, induction of MAPK pathways as well as its response to different commercially available drugs and compounds...
November 29, 2017: BMC Cancer
N Bojovic, M Raicevic, D Zivanovic, S Ducic
Aneurysmal bone cysts (ABC) are rare and they represent 1- 1.4 % of all primary bone tumors. ABC of cuboid bone are extremely rare, especially in children. Very few cases have been reported in the literature since 1967. We present a case of pathological fracture of cuboid bone due to an aneurysmal cyst in a 10-year-old girl. Surgery was performed, which included open biopsy with aspiration and intralesional curettage . Bone defect was then filled in by fully synthetic cancellous bone graft substitute consisting of pure β-tricalcium phosphate...
December 2016: Acta Orthopaedica Belgica
Anna Wieczorek, Kamil Dulski, Szymon Niedźwiecki, Dominika Alfs, Piotr Białas, Catalina Curceanu, Eryk Czerwiński, Andrzej Danel, Aleksander Gajos, Bartosz Głowacz, Marek Gorgol, Beatrix Hiesmayr, Bożena Jasińska, Krzysztof Kacprzak, Daria Kamińska, Łukasz Kapłon, Andrzej Kochanowski, Grzegorz Korcyl, Paweł Kowalski, Tomasz Kozik, Wojciech Krzemień, Ewelina Kubicz, Mateusz Kucharek, Muhsin Mohammed, Monika Pawlik-Niedźwiecka, Marek Pałka, Lech Raczyński, Zbigniew Rudy, Oleksandr Rundel, Neha G Sharma, Michał Silarski, Tomasz Uchacz, Wojciech Wiślicki, Bożena Zgardzińska, Marcin Zieliński, Paweł Moskal
A novel plastic scintillator is developed for the application in the digital positron emission tomography (PET). The novelty of the concept lies in application of the 2-(4-styrylphenyl)benzoxazole as a wavelength shifter. The substance has not been used as scintillator dopant before. A dopant shifts the scintillation spectrum towards longer wavelengths making it more suitable for applications in scintillators of long strips geometry and light detection with digital silicon photomultipliers. These features open perspectives for the construction of the cost-effective and MRI-compatible PET scanner with the large field of view...
2017: PloS One
Teppei Nakamura, Osamu Ichii, Takao Irie, Tatsuya Mizoguchi, Akio Shinohara, Hirokazu Kouguchi, Yuji Sunden, Saori Otsuka-Kanazawa, Yaser Hosny Ali Elewa, Chihiro Koshimoto, Ken-Ichi Nagasaki, Yasuhiro Kon
Pharyngeal pouches in mammals develop into specific derivatives. If the differentiation of the pharyngeal pouches is anomalous, their remnants can result in cysts, sinuses, and fistulae in the differentiated organs or around the neck. In the present study, we found several pharyngeal pouch remnants, such as cystic structures in thymus and parathyroid gland and fossulae extended from the piriform fossa, in the inbred cotton rats maintained at Hokkaido Institute of Public Health (HIS/Hiph) and University of Miyazaki (HIS/Mz)...
November 21, 2017: Histology and Histopathology
Magnus Röding
We performed computational screening of effective diffusivity in different configurations of cubes and cuboids compared with spheres and ellipsoids. In total, more than 1500 structures are generated and screened for effective diffusivity. We studied simple cubic and face-centered cubic lattices of spheres and cubes, random configurations of cubes and spheres as a function of volume fraction and polydispersity, and finally random configurations of ellipsoids and cuboids as a function of shape. We found some interesting shape-dependent differences in behavior, elucidating the impact of shape on the targeted design of granular materials...
November 16, 2017: Soft Matter
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