keyword
https://read.qxmd.com/read/38523345/assessment-of-thyroid-gland-in-children-with-point-of-care-ultrasound-pocus-radiological-performance-and-feasibility-of-handheld-ultrasound-in-clinical-practice
#1
JOURNAL ARTICLE
Ahmet Anık, Mustafa Gök, Göksel Tuzcu
BACKGROUND: Point-of-Care Ultrasound (POCUS) refers to the use of portable ultrasound machines to perform quick and focused ultrasound examinations at a patient's bedside or point-of-care. POCUS can be performed by all health workers with specific training to use POCUS. This study aimed to investigate the radiological performance and feasibility of POCUS using a handheld ultrasound (HHUSD) system in children from the perspective of the thyroid gland perspective. MATERIAL-METHODS: A pediatric endocrinologist performed thyroid imaging in children referred to our hospital with suspected thyroid disease using an HHUSD system...
March 25, 2024: Journal of Clinical Research in Pediatric Endocrinology
https://read.qxmd.com/read/33085069/thyroid-hormones-reduce-nicotinic-receptor-mediated-currents-in-sh-sy5y-neuroblastoma-cells
#2
JOURNAL ARTICLE
Giulia Puia, Federica Ravazzini
BACKGROUND: Thyroid hormones (THs) are crucial for maturation and functioning of mammalian CNS. THs "classical" signaling involves nuclear receptors binding but also their non genomic actions, as rapid modulators of cell activity, are widely recognized. Since THs imbalance affects cognition and the cholinergic system is deeply involved in learning and memory processes we have studied THs effects at the level of the nicotinic acetylcholine receptors (nAchR). METHODS: We used the patch-clamp technique to analyze T3 and T4 modulation of nicotine (NIC)-mediated current in SH-SY5Y neuroblastoma cells...
December 2020: Pharmacological Reports: PR
https://read.qxmd.com/read/32976319/comparison-of-efficiencies-between-shear-wave-elastography-fine-needle-aspiration-biopsy-and-american-college-of-radiology-thyroid-imaging-reporting-and-data-system-scoring-system-in-determining-the-malignity-potential-of-solid-thyroid-nodules
#3
JOURNAL ARTICLE
Alpaslan Yavuz, İbrahim Akbudak, Rifki Üçler, Mesut Özgökçe, Harun Arslan, Abdussamed Batur
We aimed to evaluate the efficiencies of quantitative shear-wave elastography, fine-needle aspiration (FNA) biopsy and American College of Radiology (ACR)-thyroid imaging reporting and data system (TIRADS) scoring system in determining the malignity potential of solid thyroid nodules. In period between September 2014 and January 2016, 191 solid thyroid nodules of 189 patients were enrolled in this study. The mean shear wave velocities of the nodules were recorded by acoustic radiation force impulse method. All nodules were classified according to ACR-TIRADS scoring system and underwent FNA procedure...
September 25, 2020: Ultrasound Quarterly
https://read.qxmd.com/read/32564862/widespread-applications-of-host-guest-interactive-cyclodextrin-functionalized-polymer-nanocomposites-its-meta-analysis-and-review
#4
REVIEW
Pooja R Bakshi, Vaishali Y Londhe
Cyclodextrins are cyclic oligosaccharides, having tyroid shape of the molecule which has a hydrophobic cavity and outer hydrophilic surface. This characteristic feature of the dextrins allows it to function as a functionalizing as well as a stabilizing agent. Polymer nanocomposites are nanoscale composites of polymers with enhanced and synergized properties of its components and have been known to have applications in various fields of chemistry, biomedical, pharmaceutical and environmental purposes to name a few...
August 15, 2020: Carbohydrate Polymers
https://read.qxmd.com/read/32519678/thyroid-cancer-incidence-and-clinicopathological-differences-in-patients-with-end-stage-renal-failure
#5
JOURNAL ARTICLE
Nazli Gulsoy Kirnap, Hakan Peker, Mahir Kirnap, Aydincan Akdur, Eda Yilmaz Akcay, Gökhan Moray
AIM: In the present study we aimed to determine the prevalence of thyroid cancer and the clinicopathological properties of papillary thyroid cancer (PTC) in a patient population undergoing dialysis for end-stage renal failure (ESRF). MATERIAL AND METHODS: We retrospectively reviewed all thyroid ultrasonography (USG) examinations performed between January 2007 and December 2015 to determine the incidence of nodular thyroid disease in ESRF and normal patient populations...
2020: Annali Italiani di Chirurgia
https://read.qxmd.com/read/30772047/primary-and-secondary-prevention-of-preterm-birth-a-review-of-systematic-reviews-and-ongoing-randomized-controlled-trials
#6
REVIEW
Anca Matei, Gabriele Saccone, Joshua P Vogel, Anthony B Armson
BACKGROUND: Preterm birth (PTB) is a leading cause of perinatal morbidity and mortality. Interventions aimed at preventing PTB can be classified as primary, secondary, or tertiary prevention. OBJECTIVE: To conduct a review of systematic reviews on the effectiveness and safety of primary and secondary preterm birth prevention interventions. SEARCH STRATEGY: A systematic literature search of the Cochrane, PubMed/Medline, EMBASE and CINAHL databases was conducted on 2 September 2015, and updated on 21 November 2016...
May 2019: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/29394980/endobronchial-mucosal-neuroma-with-sarcoidosis
#7
JOURNAL ARTICLE
Ipek Erdem, Dildar Duman, Selma Eroglu, Meltem Agca, Aykut Erdagi, Hatice Turker, Armagan Hazar
A first case of endobronchial mucosal neuroma with sarcoidosis is hereby reported. A 67-year female patient, who was diagnosed as sarcoidosis previously, was admitted to our hospital with symptoms of dyspnea, chest pain and fatigue. Middle lobe atelectasis and endobronchial lesion were observed in thorax computed tomography (CT). Fiberoptic bronchoscopy revealed polypoid lesions and histopathological examination of biopsy material showed clustered nerve bundles consistent with mucosal neuroma and non-necrotising granulomas consistent with sarcoidosis...
February 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://read.qxmd.com/read/29296178/prognostic-relevance-of-ttf-1-expression-in-stage-i-adenocarcinoma
#8
JOURNAL ARTICLE
Chao Zhou, Jikai Zhao, Jinchen Shao, Wentao Li
Tyroid transcription factor-1 (TTF-1) motivates the differentiation and development of bronchioloalveolar cells. The association of TTF-1 expression with prognosis in stage I adenocarcinoma is unclear. This study enrolled patients with resected stage I pulmonary adenocarcinoma who had TTF-1 immunostaining. All the corresponding clinicopathologic data including sex, age, smoking history, pathologic T stage, pathologic disease stage, surgical procedure, subtypes, follow-up records and adjuvant chemotherapy were investigated...
December 8, 2017: Oncotarget
https://read.qxmd.com/read/29147785/qt-interval-and-dispersion-in-drug-free-anorexia-nervosa-adolescents-a-case-control-study
#9
JOURNAL ARTICLE
Monica Bomba, Lucio Tremolizzo, Fabiola Corbetta, Franco Nicosia, Francesca Lanfranconi, Gianni Poggioli, Karine Goulene, Marco Stramba-Badiale, Elisa Conti, Francesca Neri, Renata Nacinovich
Long QT values have been reported in patients with anorexia nervosa of the restricting type (ANr) potentially increasing the risk of fatal arrhythmia, especially if psychotropic drug treatment is required. Nevertheless, the previous studies on this topic are biased by drug exposure, long disease durations, and small sample sizes. This study is aimed at assessing QTc and QTcd values in ANr adolescents with recent onset and drug free, as compared to subjects affected by psychiatric disorders other than ANr. We evaluated QTc and its dispersion (QTcd) in a population of 77 drug-free ANr female adolescents and compared to an equal number of healthy controls (H-CTRL) and pathological controls (P-CTRL, mixed psychiatric disorders)...
July 2018: European Child & Adolescent Psychiatry
https://read.qxmd.com/read/28042533/a-brief-review-on-the-molecular-basis-of-medullary-thyroid-carcinoma
#10
REVIEW
Masoumeh Mohammadi, Mehdi Hedayati
Approximately 5-10% of all thyroid cancers are medullary thyroid carcinomas (MTC). MTC is mainly sporadic in nature, but 20-30% of cases are hereditary. Genetic testing for hereditary MTC is very important for the patient and his family, but the patients must be receiving appropriate genetic counseling. About 98% of patients with hereditary MTC have germline mutations in exons 10, 11, 13, 14, 15, 16 and intron 16 of the REarrangement during transfection (RET) proto-oncogene, but the etiology of the more frequent sporadic form of MTC (sMTC) is not well understood...
2017: Cell Journal
https://read.qxmd.com/read/26725000/semen-evaluation-in-four-autochthonous-wild-raptor-species-using-computer-aided-sperm-analyzer
#11
JOURNAL ARTICLE
Andrea Dogliero, Ada Rota, Renato Lofiego, Mitzy Mauthe von Degerfeld, Giuseppe Quaranta
At least 10 percent of the approximately 300 species of the order Falconiformes are listed as being globally threatened. The present work describes the seminal characteristics of three diurnal and one nocturnal raptor species. Semen was collected from clinically healthy Accipiter nisus (n = 1), Falco subbuteo (n = 6), and Falco tinnunculus (n = 5) adult males that were housed at the 'Centro Animali Non Convenzionali' of the Department of Veterinary Sciences of the University of Turin. The semen was collected after a period of recovery and before their release as well as from seven Bubo bubo males bred in captivity as part of a raptor conservation project...
April 1, 2016: Theriogenology
https://read.qxmd.com/read/26636972/synchronous-thyroid-metastasis-from-lung-adenocarcinoma
#12
REVIEW
Matteo Rossini, Livia Ruffini, Luca Ampollini, Federico Cozzani, Paolo Del Rio
UNLABELLED: Metastases from other primary malignancies to the thyroid gland are clinically uncommon, far less frequent than any malignant primary neoplasm, mostly affecting elderly patients. Recent autopsy studies have shown that metastases to the tyroid is relatively common, with a prevalence of of 1,9-24%. We present a case of a man (72 years old) with lung cancer and synchronous metastasis to thyroid gland. Typically the interval between the diagnosis of the primary tumor and the detection of thyroid metastasis is from one month to 26 years...
2015: Annali Italiani di Chirurgia
https://read.qxmd.com/read/25524940/associations-of-mir-146a-and-mir-146b-expression-and-clinical-characteristics-in-papillary-thyroid-carcinoma
#13
JOURNAL ARTICLE
Mei Sun, Sheng Fang, Weiwei Li, Chengqian Li, Luan Wang, Fang Wang, Yangang Wang
BACKGROUND: Human miRNAs have emerged as potentially useful diagnostic and prognostic markers in cancer within the past decade. Abnormal expression of microRNA-146 (miR-146) has been found in several classes of cancers. OBJECTIVE: To explore expression and clinical associations of miR-146a and miR-146b in papillary thyroid carcinoma. METHODS: We investigated expressions of miR-146a and miR-146b in tissues and peripheral blood among 128 patients with primary PTC, 120 patients with nodular goiter and 120 healthy controls by RT-PCR...
2015: Cancer Biomarkers: Section A of Disease Markers
https://read.qxmd.com/read/22693968/comparison-of-the-therapeutic-effects-of-tri-iodothyronine-and-methylprednisolone-during-early-sepsis-in-laboratory-animals
#14
COMPARATIVE STUDY
F Coskun, B Saylam, B Kulah, I Dolapci, A Sungur, M Vasfi Ozer
BACKGROUND: Despite major advances, the treatment of sepsis is still a challenging problem for surgeons. This study was aimed to compare the therapeutic effects of methylprednisolone and tri-iodothyronine replacement therapy during an early sepsis. MATERIAL AND METHODS: Forty male Wistar albino rats weighing 300-340 g were divided into the Control, CLP, CLP/MP, CLP/T3 and CLP/MP/T3 groups. The Control group underwent a sham operation. Only cecal ligation and puncture was performed in the CLP group...
2012: Bratislavské Lekárske Listy
https://read.qxmd.com/read/20578591/-polycystic-ovary-syndrome-and-autoimmune-diseases
#15
REVIEW
J Petríková, I Lazúrová
Polycystic ovary syndrome (PCOS) is characterized by laboratory or clinical signs of hyperandrogenism with chronic anovulation and is currently one of the most frequent endocrinopaties in women of fertile age. Syndrome is associated with a variety of endocrine and metabolic disturbances and according to results of scientific work could be possibly associated with some autoimmune diseases. It seems that the prevalence of autoimmune tyroiditis is important among these patients. Recent studies reveal higher incidence of organ - non specific autoantibodies, but their clinical significance is unknown to date...
May 2010: Vnitr̆ní Lékar̆ství
https://read.qxmd.com/read/19468796/intraoperative-gamma-probe-guidance-with-99mtc-pertechnetate-in-the-completion-thyroidectomy
#16
JOURNAL ARTICLE
Gülseren Aras, Salih Sinan Gültekin, Nuriye Ozlem Küçük, Seher Demirer, Tuğbay Tuğ
AIM: Intraoperative gamma probe (GP) guidance with (99m)Tc-pertechnetate in the completion total thyroidectomy after a first thyroidectomy was investigated in this prospective study. METHODS: The study group comprises of fourteen consecutive patients (14 females, age mean 50.2 +/- 12.0 years, age range 29-73 years). All patients underwent a second thyroidectomy due to inadequate (5/14 patients) and complementary (9/14 patients) interventions. Serum-free three iodothyronine, free thyroxin and thyroid stimulating hormone measurements, a neck ultrasonography (USG) and thyroid scintigraphy (TS) were performed in the preoperative and postoperative period...
July 2009: Annals of Nuclear Medicine
https://read.qxmd.com/read/18341829/-usefulness-of-galectin-3-expression-in-the-clinical-behavior-of-differentiated-thyroid-carcinoma
#17
JOURNAL ARTICLE
Pedro López Mondéjar, Antonio Picó, Javier Seguí, Alicia López Maciá
BACKGROUND AND OBJECTIVE: Our objective was to quantify the galectin-3 (gal-3) expression in differentiated thyroid carcinoma and study its relation with the clinical behavior of these tumors. PATIENTS AND METHOD: We investigated the immunohistochemical reaction of gal-3 in patients with papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) and performed a retrospective study in order to find correlations with clinical features. Gal-3 expression was studied in 53 differentiated tyroid carcinomas (42 PTC and 11 FTC), and was related with clinical features: metastases, extrathyroid invasion and initial stage in the diagnosis and persistence disease and relapses in the follow up...
February 16, 2008: Medicina Clínica
https://read.qxmd.com/read/17522123/3-5-diiodothyronine-in-vivo-maintains-euthyroidal-expression-of-type-2-iodothyronine-deiodinase-growth-hormone-and-thyroid-hormone-receptor-beta1-in-the-killifish
#18
JOURNAL ARTICLE
C García-G, L López-Bojorquez, J Nuñez, C Valverde-R, A Orozco
Until recently, 3,5-diiodothyronine (3,5-T(2)) has been considered an inactive by-product of triiodothyronine (T(3)) deiodination. However, studies from several laboratories have shown that 3,5-T(2) has specific, nongenomic effects on mitochondrial oxidative capacity and respiration rate that are distinct from those due to T(3). Nevertheless, little is known about the putative genomic effects of 3,5-T(2). We have previously shown that hyperthyroidism induced by supraphysiological doses of 3,5-T(2) inhibits hepatic iodothyronine deiodinase type 2 (D2) activity and lowers mRNA levels in the killifish in the same manner as T(3) and T(4), suggesting a pretranslational effect of 3,5-T(2) (Garcia-G C, Jeziorski MC, Valverde-R C, Orozco A...
August 2007: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://read.qxmd.com/read/16568018/-nearly-total-thyroidectomy-versus-total-thyroidectomy-our-experience
#19
COMPARATIVE STUDY
G Candela, S Varriale, L Di Libero, A Maschio, M Giordano, F Manetta, P Sullo, V Casaburi, M Lanza, L Santini
AIM: Generally, the classification of thyroidectomy as benign pathology is: multinodular toxic goitre, simple goitre, toxic adenoma, Base-dow disease, Hashimoto's tyroiditis Subtotal thyroidectomy provides for the removal of the gland except for a bilateral residue of about 6-10 g, near total thyroidectomy provides for the near total removal of the gland except for a residue inferior to 5 grams. Near total thyroidectomy has taken the place of the subtotal thyroidectomy. METHODS: In two years, in our institute, there have been exeuted: 96 near total thyrodectomies, 96 total thyroidetomies, 8 lobectomies ad two revues for recurrencies...
February 2006: Minerva Chirurgica
https://read.qxmd.com/read/15754729/age-as-a-predictor-of-recurrent-hypothyroidism-in-patients-with-post-partum-thyroid-dysfunction
#20
JOURNAL ARTICLE
F Azizi
The long term effect of post-partum thyroid dysfunction (PPTD) is not well established. This study was conducted to evaluate the outcome of permanent hypothyroidism and factors predictive of thyroid dysfunction in a large cohort of women with PPTD. In 164 women, treated with levothyroxine for moderate and severe post- partum hypothyroidism, the treatment was discontinued and subjects were followed-up for the recurrence of hypothyroidism. Factors such as thyroid function tests, tyroid peroxidase antibodies (TPOAb) titers, multiparity, history of autoimmune disorders, smoking habits, use of oral contraceptives, family history of thyroid disease, goiter size and age at active phase of PPTD were assessed...
December 2004: Journal of Endocrinological Investigation
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