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https://www.readbyqxmd.com/read/29155117/pediatric-non-missile-penetrating-head-injury-case-series-and-literature-review
#1
REVIEW
Evangelos Drosos, Dimitrios Giakoumettis, Alexandros Blionas, Andreas Mitsios, Georgios Sfakianos, Marios Themistocleous
BACKGROUND: Pediatric non-missile penetrating head injury (NMPHI) is usually accidental attributed mainly to the softer skulls of growing children. However, it is a rather rare entity and therefore no consensus exists regarding treatment, in order to effectively prevent the immediate and long-term complications. Throughout the literature practice, essentials are mostly discussed in case reviews and case series in general population. No data originating from randomized studies are available due to ethical and practical limitations...
November 15, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29139100/-guidelines-for-non-invasive-and-invasive-home-mechanical-ventilation-for-treatment-of-chronic-respiratory-failure-update-2017
#2
W Windisch, M Dreher, J Geiseler, K Siemon, J Brambring, D Dellweg, B Grolle, S Hirschfeld, T Köhnlein, U Mellies, S Rosseau, B Schönhofer, B Schucher, A Schütz, H Sitter, S Stieglitz, J Storre, M Winterholler, P Young, S Walterspacher
Today, invasive and non-invasive home mechanical ventilation have become a well-established treatment option. Consequently, in 2010 the German Society of Pneumology and Mechanical Ventilation (DGP) has leadingly published the guidelines on "Non-Invasive and Invasive Mechanical Ventilation for Treatment of Chronic Respiratory Failure". However, continuing technical evolutions, new scientific insights, and health care developments require an extensive revision of the guidelines.For this reason, the updated guidelines are now published...
November 2017: Pneumologie
https://www.readbyqxmd.com/read/29135293/-from-the-hallervorden-spatz-eponym-to-the-molecular-terminology
#3
Ferenc Garzuly
INTRODUCTION AND AIM: A combination of Niemann-Pick- and Hallervorden-Spatz diseases led to the death of a 17-year-old boy in 1994. Genetic counseling necessitated further investigations in 2017. Meanwhile, the nomenclature of Hallervorden-Spatz disease has been abandoned. The author analyze the reasons for this change. METHOD: Professional activities of Hallervorden and Spatz during and after the Nazi euthanasia program are presented. Also, the scientific efforts that led to the discovery of the genetic background of the disease and ultimately to its new name are highlighted...
October 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29128922/causes-of-renal-oligohydramnios-impact-on-prenatal-counseling-and-postnatal-outcome
#4
EDITORIAL
Sebastian Loos, Markus J Kemper
The presence of renal oligohydramnios (ROH) in a fetus has been associated in the past with a poor prognosis for survival, although recent studies have shown that survival has improved considerably due to the advances in neonatology and pediatric nephrology. In an article recently published in Pediatric Nephrology, evaluation of a large series by Mehler and colleagues confirms the improved prognosis, showing a survival rate of 32 of 38 (84%). In addition, only 12 of 35 (34%) neonates required renal replacement therapy...
November 11, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29114060/ethics-rounds-death-after-pediatric-dental-anesthesia-an-avoidable-tragedy
#5
Helen Lee, Peter Milgrom, Colleen E Huebner, Philip Weinstein, Wylie Burke, Erika Blacksher, John D Lantos
Early childhood caries (ECC) is the single most common chronic childhood disease. In the treatment of ECC, children are often given moderate sedation or general anesthesia. An estimated 100 000 to 250 000 pediatric dental sedations are performed annually in the United States. The most common medications are benzodiazepines, opioids, local anesthetics, and nitrous oxide. All are associated with serious adverse events, including hypoxemia, respiratory depression, airway obstruction, and death. There is no mandated reporting of adverse events or deaths, so we don't know how often these occur...
November 7, 2017: Pediatrics
https://www.readbyqxmd.com/read/29104389/eruption-chronology-in-children-a-cross-sectional-study
#6
Neha Verma, Arpana Bansal, Parimala Tyagi, Ankur Jain, Utkarsh Tiwari, Ruchika Gupta
Aims and objectives: The purpose of this study is to determine the appropriate reference standard for eruption timing of primary teeth in infants and preschool children of Bhopal city and to determine the role of various factors affecting the eruption of primary dentition. Materials and methods: A cross-sectional study was conducted among the infants and preschool children (4-36 months) attending the local government or private hospitals, and vaccination centers...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29101225/weighing-the-social-and-ethical-considerations-of-maternal-fetal-surgery
#7
Ryan M Antiel, Alan W Flake, Christopher A Collura, Mark P Johnson, Natalie E Rintoul, John D Lantos, Farr A Curlin, Jon C Tilburt, Stephen D Brown, Chris Feudtner
OBJECTIVES: The ethics of maternal-fetal surgery involves weighing the importance of potential benefits, risks, and other consequences involving the pregnant woman, fetus, and other family members. We assessed clinicians' ratings of the importance of 9 considerations relevant to maternal-fetal surgery. METHODS: This study was a discrete choice experiment contained within a 2015 national mail-based survey of 1200 neonatologists, pediatric surgeons, and maternal-fetal medicine physicians, with latent class analysis subsequently used to identify groups of physicians with similar ratings...
November 3, 2017: Pediatrics
https://www.readbyqxmd.com/read/29045241/taking-assent-to-new-heights-a-case-report-on-do-not-resuscitate-status-in-pediatric-palliative-care-procedures
#8
Heather A Ballard, Santhanam Suresh
Dying adolescents presenting for palliative procedures have complicated developmental and ethical issues, especially when reconsidering do-not-resuscitate orders. Though the American Academy of Pediatrics has guidelines, there is limited information in the literature on how to take care of these patients. We describe the case of a 14-year-old patient presenting to the interventional radiology suite for management of superior vena cava syndrome. The patient's goals of treatment were elucidated through a comprehensive care team consisting of the procedural and oncology teams...
October 17, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29038859/refashioned-lamb-tissue-as-an-animal-model-for-training-complex-techniques-of-laryngotracheal-stenosis-surgery
#9
Lluís Nisa, Pedro Teiga, Gustavo Barreto da Cunha, Biswanath Roy, Riza Onder Gunaydin, Kishore Sandu
Open reconstructive upper airway surgery for laryngotracheal stenosis (LTS), whether for subglottic or tracheal stenosis, constitutes a group of complex approaches. LTS requiring open reconstruction is overall rare and primarily performed at tertiary centres. This poses an obvious challenge for the acquisition and maintenance of surgical skills for this group of complex approaches. In this context, animal models provide a unique opportunity for open reconstructive airway surgery training. Such models ought to take into consideration ethical aspects, be easily available and easy to maintain, and have similar macroscopic anatomical features to the human laryngotracheal frame...
December 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29032585/infection-surveillance-in-pediatric-hematopoietic-stem-cell-transplantation-recipients
#10
Daniela Caldas Teixeira, Lilian Martins Oliveira Diniz, Paulo Henrique Orlandi Mourão, Fabiana Maria Kakehashi, Antonio Vaz de Macedo, Helena Duani, Wanessa Trindade Clemente, Karla Emília de Sá Rodrigues, Roberta Maia de Castro Romanelli
OBJECTIVE: Describe the profile of reported Healthcare-Associated Infections (HAIs) in pediatric patients submitted to hematopoietic stem cell transplantation (HSCT) at a reference center. METHODS: Retrospective cohort of pediatric patients who were submitted to HSCT from 2008 to 2016. The criteria for HAI were based on those established by the National Healthcare Safety Network. Data were collected by active surveillance performed daily by professionals. This study was approved by the Institutional Research Ethics Committee...
October 15, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/29031040/-treatment-refusal-in-pediatric-oncology
#11
A Špótová, K Husáková, A Hrašková, M Mikesková, J Puškáčová, S Hederová, M Jamárik, E Rabenseifertová, Z Jalovecká, A Kolenová, Z Šubová
BACKGROUND: Pediatric oncologists are often faced with situations in which parents or guardians refuse recommended treatment for curable childhood cancer. Deciding how to proceed in such situations is an ethical dilemma. The aim of this article is to consider optimal approaches when parents are strongly against oncological treatment, potentially compromising their childrens rights for health care and to the chance for cure. CASES: In this paper, we report two cases of treatment refusal from our department and the impact of such decisions on the children themselves...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28992658/-the-pl%C3%A3-ner-model-for-the-school-entry-screening-is-a-role-model-for-the-future
#12
Josef Weigl
Background The Plöner Model is a stepwise-selective model, similar to the one practised in all of Bavaria since 2008. It was already developed in 2002/2003 for the school entry screening and has been in use since then. Such models are intermittently criticized since not each child is seen by a doctor. Methods The procedure and data of the Plöner Model are analyzed and put into a wider context within Germany and beyond. The current programs in place are therefore categorized into 3 groups and compared with regard to public heath ethics criteria...
October 9, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28992388/impact-of-nutrition-interventions-on-pediatric-mortality-and-nutrition-outcomes-in-humanitarian-emergencies
#13
REVIEW
Kamna S Balhara, David M Silvestri, W Tyler Winders, Anand Selvam, Sean M Kivlehan, Torben K Becker, Adam C Levine
OBJECTIVES: Malnutrition contributes to pediatric morbidity and mortality in disasters and complex emergencies, but summary data describing specific nutritional interventions in these settings are lacking. This systematic review aims to characterize such interventions and their effects on pediatric mortality, anthropometric measures, and serum markers of nutrition. METHODS: A systematic search of OVID Medline, Cochrane Library, and relevant grey literature was conducted...
October 9, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28976458/evaluation-of-the-c-mac-miller-video-laryngoscope-sizes-0-and-1-during-tracheal-intubation-of-infants-less-than-10-kg
#14
Florian J Raimann, Colleen E Cuca, Detlev Kern, Kai Zacharowski, Udo Rolle, Dirk Meininger, Christian F Weber, Christian Byhahn, Haitham Mutlak
STUDY OBJECTIVE: Video laryngoscopy has primarily been developed to assist in difficult airways. Using video laryngoscopy in pediatric airway management is an up-and-coming topic. The aim of the presented study was to compare the intubation conditions obtained when using the C-MAC video laryngoscope with Miller blades sizes 0 and 1 for standard direct laryngoscopy and indirect laryngoscopy in children weighing less than 10 kg. DESIGN: This was a prospective study...
October 2, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28974245/dose-escalation-study-of-intravenous-and-intra-arterial-n-acetylcysteine-for-the-prevention-of-oto-and-nephrotoxicity-of-cisplatin-with-a-contrast-induced-nephropathy-model-in-patients-with-renal-insufficiency
#15
Edit Dósa, Krisztina Heltai, Tamás Radovits, Gabriella Molnár, Judit Kapocsi, Béla Merkely, Rongwei Fu, Nancy D Doolittle, Gerda B Tóth, Zachary Urdang, Edward A Neuwelt
BACKGROUND: Cisplatin neuro-, oto-, and nephrotoxicity are major problems in children with malignant tumors, including medulloblastoma, negatively impacting educational achievement, socioemotional development, and overall quality of life. The blood-labyrinth barrier is somewhat permeable to cisplatin, and sensory hair cells and cochlear supporting cells are highly sensitive to this toxic drug. Several chemoprotective agents such as N-acetylcysteine (NAC) were utilized experimentally to avoid these potentially serious and life-long side effects, although no clinical phase I trial was performed before...
October 3, 2017: Fluids and Barriers of the CNS
https://www.readbyqxmd.com/read/28967605/-22q11-2%C3%A2-microdeletion-syndrome-analysis-of-the-care-pathway-before-the-genetic-diagnosis
#16
T Ingrao, L Lambert, M Valduga, G Bosser, E Albuisson, B Leheup
BACKGROUND: 22q11.2 deletion syndrome (22q11.2DS) is a very broad phenotypic spectrum disorder. It can affect many organs or systems. 22q11.2DS is the most common microdeletion syndrome in humans, with a prevalence ranging from one in every 2000 to one in 4000 newborns. It seems to be more prevalent than reported and under-recognized or undiagnosed because of its inherent clinical variability and heterogeneity. In France, 15,000 patients may be affected by this disease, more than half without knowing it...
November 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28961265/clinicians-attitude-towards-family-planning-and-timing-of-diagnosis-in-autosomal-dominant-polycystic-kidney-disease
#17
Stéphanie De Rechter, Jonathan Kringen, Peter Janssens, Max Christoph Liebau, Koenraad Devriendt, Elena Levtchenko, Carsten Bergmann, François Jouret, Bert Bammens, Pascal Borry, Franz Schaefer, Djalila Mekahli
Several ethical aspects in the management of Autosomal Dominant Polycystic Kidney Disease (ADPKD) are still controversial, including family planning and testing for disease presence in at-risk individuals. We performed an online survey aiming to assess the opinion and current clinical practice of European pediatric and adult nephrologists, as well as geneticists. A total of 410 clinicians (53% male, mean (SD) age of 48 (10) years) responded, including 216 pediatric nephrologists, 151 adult nephrologists, and 43 clinical geneticists...
2017: PloS One
https://www.readbyqxmd.com/read/28953004/fertility-preservation-in-children-and-adolescents-current-options-and-considerations
#18
Kate McCracken, Leena Nahata
PURPOSE OF REVIEW: The purpose of this review is to outline current pediatric fertility preservation options, and discuss ethical and financial considerations impacting this rapidly expanding field. RECENT FINDINGS: With the improvement in treatment of pediatric malignancies and medical conditions that threaten fertility, survival rates are increasing. Therefore, minimizing long-term morbidities such as gonadal damage and infertility is of utmost importance. Impaired fertility not only has a significant negative impact on patient's quality of life; in women, gonadal damage puts patients at risk for premature menopause, and increased risk of cardiac, skeletal, and cognitive issues...
August 4, 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28952341/dexmedetomidine-use-in-a-pediatric-intensive-care-unit-a-retrospective-cohort-study
#19
Heidi L Banasch, Deonne A Dersch-Mills, Leah L Boulter, Elaine Gilfoyle
BACKGROUND: Use of dexmedetomidine in critically ill pediatric patients is increasing despite limited data on effects on mechanical ventilation times, use of other sedatives, adverse effects, and withdrawal. OBJECTIVES: To describe the use and tolerability of dexmedetomidine in a large cohort of critically ill children. METHODS: This was a retrospective cohort study of patients receiving dexmedetomidine in a pediatric intensive care unit. Ethical approval was granted by the local review board...
September 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28949869/better-to-know-than-to-imagine-including-children-in-their-health-care
#20
Tenzin Wangmo, Eva De Clercq, Katharina M Ruhe, Maja Beck-Popovic, Johannes Rischewski, Regula Angst, Marc Ansari, Bernice S Elger
BACKGROUND: This article describes the overall attitudes of children, their parents, and attending physicians toward including or excluding pediatric patients in medical communication and health care decision-making processes. METHODS: Fifty-two interviews were carried out with pediatric patients (n = 17), their parents (n = 19), and attending oncologists (n = 16) in eight Swiss pediatric oncology centers. The interviews were analyzed using thematic coding. RESULTS: Parenting styles, the child's personality, and maturity are factors that have a great impact upon the inclusion of children in their health care processes...
January 2017: AJOB Empirical Bioethics
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