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https://www.readbyqxmd.com/read/28426646/community-mitigation-guidelines-to-prevent-pandemic-influenza-united-states-2017
#1
Noreen Qualls, Alexandra Levitt, Neha Kanade, Narue Wright-Jegede, Stephanie Dopson, Matthew Biggerstaff, Carrie Reed, Amra Uzicanin
When a novel influenza A virus with pandemic potential emerges, nonpharmaceutical interventions (NPIs) often are the most readily available interventions to help slow transmission of the virus in communities, which is especially important before a pandemic vaccine becomes widely available. NPIs, also known as community mitigation measures, are actions that persons and communities can take to help slow the spread of respiratory virus infections, including seasonal and pandemic influenza viruses.These guidelines replace the 2007 Interim Pre-pandemic Planning Guidance: Community Strategy for Pandemic Influenza Mitigation in the United States - Early, Targeted, Layered Use of Nonpharmaceutical Interventions (https://stacks...
April 21, 2017: MMWR. Recommendations and Reports: Morbidity and Mortality Weekly Report. Recommendations and Reports
https://www.readbyqxmd.com/read/28423062/filamentous-fungal-carbon-catabolite-repression-supports-metabolic-plasticity-and-stress-responses-essential-for-disease-progression
#2
Sarah R Beattie, Kenneth M K Mark, Arsa Thammahong, Laure Nicolas Annick Ries, Sourabh Dhingra, Alayna K Caffrey-Carr, Chao Cheng, Candice C Black, Paul Bowyer, Michael J Bromley, Joshua J Obar, Gustavo H Goldman, Robert A Cramer
Aspergillus fumigatus is responsible for a disproportionate number of invasive mycosis cases relative to other common filamentous fungi. While many fungal factors critical for infection establishment are known, genes essential for disease persistence and progression are ill defined. We propose that fungal factors that promote navigation of the rapidly changing nutrient and structural landscape characteristic of disease progression represent untapped clinically relevant therapeutic targets. To this end, we find that A...
April 19, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28420188/health-risk-assessment-of-indoor-air-quality-socioeconomic-and-house-characteristics-on-respiratory-health-among-women-and-children-of-tirupur-south-india
#3
Krassi Rumchev, Yun Zhao, Jeffery Spickett
Background: Indoor air pollution is still considered as one of the leading causes of morbidity and mortality worldwide and especially in developing countries, including India. This study aims to assess social, housing, and indoor environmental factors associated with respiratory health among mothers and children. Methods: The study was conducted in the city of Tirupur, South India. We quantitatively assessed the indoor exposure to fine particulate matter (PM2.5) and carbon monoxide in relation to respiratory health among women and children...
April 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28407367/a-review-of-early-influences-on-physical-activity-and-sedentary-behaviors-of-preschool-age-children-in-high-income-countries
#4
REVIEW
Ana Cristina Lindsay, Mary L Greaney, Sherrie F Wallington, Tatiana Mesa, Carlos F Salas
PURPOSE: Promoting physical activity (PA) is a key component of preventing and controlling childhood obesity. Despite well-documented benefits of PA, globally, rates of PA among young children have declined over the past decades, and most children are not accruing sufficient PA daily. Helping children develop the foundation for PA habits early in life is critical for the promotion of health in childhood and prevention of chronic diseases later in life, and will ultimately promote longer and healthier lives for individuals and the general population...
April 13, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/28404552/priority-setting-in-paediatric-preventive-care-research
#5
Mikael Lavigne, Catherine S Birken, Jonathon L Maguire, Sharon Straus, Andreas Laupacis
OBJECTIVES: To identify the unanswered research questions in paediatric preventive care that are most important to parents and clinicians, and to explore how questions from parents and clinicians may differ. DESIGN: Iterative mixed methods research priority setting process. SETTING: Toronto, Ontario, Canada. PARTICIPANTS: Parents of children aged 0-5 years enrolled in a research network in Toronto, and clinicians practising in Toronto, Ontario, Canada...
April 12, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28403870/noise-sensitivity-rather-than-noise-level-predicts-the-non-auditory-effects-of-noise-in-community-samples-a-population-based-survey
#6
Jangho Park, Seockhoon Chung, Jiho Lee, Joo Hyun Sung, Seung Woo Cho, Chang Sun Sim
BACKGROUND: Excessive noise affects human health and interferes with daily activities. Although environmental noise may not directly cause mental illness, it may accelerate and intensify the development of latent mental disorders. Noise sensitivity (NS) is considered a moderator of non-auditory noise effects. In the present study, we aimed to assess whether NS is associated with non-auditory effects. METHODS: We recruited a community sample of 1836 residents residing in Ulsan and Seoul, South Korea...
April 12, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28402148/should-modulation-of-p50-be-a-therapeutic-target-in-the-critically-ill
#7
Amudan J Srinivasan, Clare Morkane, Daniel S Martin, Ian J Welsby
A defining feature of human hemoglobin is its oxygen binding affinity, quantified by the partial pressure of oxygen at which hemoglobin is 50% saturated (p50), and the variability of this parameter over a range of physiological and environmental states. Modulation of this property of hemoglobin can directly affect the degree of peripheral oxygen offloading and tissue oxygenation. Areas covered: This review summarizes the role of hemoglobin oxygen affinity in normal and abnormal physiology and discusses the current state of the literature regarding artificial modulation of p50...
April 12, 2017: Expert Review of Hematology
https://www.readbyqxmd.com/read/28400957/sociodemographic-behavioral-and-environmental-factors-of-child-mortality-in-eastern-region-of-cameroon-results-from-a-social-autopsy-study
#8
Alain K Koffi, Romain S Wounang, Félicitée Nguefack, Seidou Moluh, Paul-Roger Libite, Henry D Kalter
BACKGROUND: While most child deaths are caused by highly preventable and treatable diseases such as pneumonia, diarrhea, and malaria, several sociodemographic, cultural and health system factors work against children surviving from these diseases. METHODS: A retrospective verbal/social autopsy survey was conducted in 2012 to measure the biological causes and social determinants of under-five years old deaths from 2007 to 2010 in Doume, Nguelemendouka, and Abong-Mbang health districts in the Eastern Region of Cameroon...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28396658/characterisation-of-aerotolerant-forms-of-a-robust-chicken-colonizing-campylobacter-coli
#9
Peter M O'Kane, Ian F Connerton
Campylobacter contaminated poultry meat is a major source of human foodborne illness. Campylobacter coli strain OR12 is a robust colonizer of chickens that was previously shown to outcompete and displace other Campylobacter strains from the chicken's gastrointestinal tract. This strain is capable of aerobic growth on blood agar. Serial aerobic passage increased this aerotolerance as assessed by quantitative assays for growth and survival on solid media. Aerotolerance was also associated with increased peroxide stress resistance...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28393756/norovirus-epidemiology-in-south-african-children-5-years-hospitalised-for-diarrhoeal-illness-between-2009-and-2013
#10
N A Page, M J Groome, S Nadan, R Netshikweta, K H Keddy, B Poonsamy, J Moyes, S Walaza, K Kahn, S A Madhi, M B Taylor, J Mans, C Cohen
Public health interest in norovirus (NoV) has increased in recent years following improved diagnostics, global burden estimates and the development of NoV vaccine candidates. This study aimed to describe the detection rate, clinical characteristics and environmental features associated with NoV detection in hospitalized children <5 years with diarrhoea in South Africa (SA). Between 2009 and 2013, prospective diarrhoeal surveillance was conducted at four sites in SA. Stool specimens were collected and screened for NoVs and other enteric pathogens using molecular and serological assays...
April 10, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28392700/urinary-cadmium-levels-predict-mortality-of-patients-with-acute-heart-failure
#11
Ching-Wei Hsu, Cheng-Hao Weng, Cheng-Chia Lee, Dan-Tzu Lin-Tan, Pao-Hsien Chu, Kuan-Hsing Chen, Tzung-Hai Yen, Wen-Hung Huang
BACKGROUND: Acute heart failure (AHF) is a serious condition that is associated with increased mortality in critically ill patients. Previous studies indicated that environmental exposure to cadmium increases mortality of general populations. However, the relationship of cadmium exposure and mortality is unclear for AHF patients. MATERIALS AND METHODS: A total of 153 patients with AHF in intensive care units (ICUs) met the inclusion criteria and were followed up for 6 months...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28388984/case-control-study-on-risk-factors-of-unplanned-extubation-based-on%C3%A2-patient-safety-model-in-critically-ill-patients-with-mechanical-ventilation
#12
EunOk Kwon, KyungSook Choi
PURPOSE: This study aimed to identify risk factors of unplanned extubation in intensive care unit (ICU) patients with mechanical ventilation using a patient safety model. METHODS: This study was designed to be a case-control study. Data collection sheets, including 29 risk factors of unplanned extubation in mechanically ventilation patients were retrospectively collected based on a patient safety model over 3 years. From 41,207 mechanically ventilated patients, 230 patients were identified to have unplanned extubation during their ICU stay...
March 2017: Asian Nursing Research
https://www.readbyqxmd.com/read/28387726/rethinking-the-epigenetic-framework-to-unravel-the-molecular-pathology-of-schizophrenia
#13
REVIEW
Ariel Cariaga-Martinez, Raúl Alelú Paz
Schizophrenia is a complex mental disorder whose causes are still far from being known. Although researchers have focused on genetic or environmental contributions to the disease, we still lack a scientific framework that joins molecular and clinical findings. Epigenetic can explain how environmental variables may affect gene expression without modifying the DNA sequence. In fact, neuroepigenomics represents an effort to unify the research available on the molecular pathology of mental diseases, which has been carried out through several approaches ranging from interrogating single DNA methylation events and hydroxymethylation patterns, to epigenome-wide association studies, as well as studying post-translational modifications of histones, or nucleosomal positioning...
April 7, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28385135/an-outbreak-of-salmonellosis-associated-with-duck-prosciutto-at-a-northern-territory-restaurant
#14
Anthony Dk Draper, Claire N Morton, Joshua Ni Heath, Justin A Lim, Anninka I Schiek, Stephanie Davis, Vicki L Krause, Peter G Markey
In June 2015, an outbreak of salmonellosis occurred among people who had eaten at a restaurant in Darwin, Northern Territory over 2 consecutive nights. We conducted a retrospective cohort study of diners who ate at the restaurant on 19 and 20 June 2015. Diners were telephoned and a questionnaire recorded symptoms and menu items consumed. An outbreak case was defined as anyone with laboratory confirmed Salmonella Typhimurium PT9 (STm9) or a clinically compatible illness after eating at the restaurant. Environmental health officers inspected the premises and collected food samples...
March 31, 2017: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/28385134/an-outbreak-of-salmonella-saintpaul-gastroenteritis-after-attending-a-school-camp-in-the-northern-territory-australia
#15
Anthony Dk Draper, Claire N Morton, Joshua Ni Heath, Justin A Lim, Peter G Markey
An outbreak of salmonellosis occurred following attendance at a school camp between 5 and 8 August 2014 in a remote area of the Northern Territory, Australia. We conducted a retrospective cohort study via telephone interviews, using a structured questionnaire that recorded symptoms and exposures to foods and activities during the camp. A case was anyone with laboratory confirmed Salmonella Saintpaul infection or a clinically compatible illness after attending the camp. Environmental health officers from the Environmental Health Branch undertook an investigation and collected water and environmental samples...
March 31, 2017: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/28384584/river-doctors-learning-from-medicine-to-improve-ecosystem-management
#16
Arturo Elosegi, Mark O Gessner, Roger G Young
Effective ecosystem management requires a robust methodology to analyse, remedy and avoid ecosystem damage. Here we propose that the overall conceptual framework and approaches developed over millennia in medical science and practice to diagnose, cure and prevent disease can provide an excellent template. Key principles to adopt include combining well-established assessment methods with new analytical techniques and restricting both diagnosis and treatment to qualified personnel at various levels of specialization, in addition to striving for a better mechanistic understanding of ecosystem structure and functioning, as well as identifying the proximate and ultimate causes of ecosystem impairment...
April 3, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28384542/gene-expression-in-blood-of-children-and-adolescents-mediation-between-childhood-maltreatment-and-major-depressive-disorder
#17
Leticia Maria Spindola, Pedro Mario Pan, Patricia Natalia Moretti, Vanessa Kiyomi Ota, Marcos Leite Santoro, Hugo Cogo-Moreira, Ary Gadelha, Giovanni Salum, Gisele Gus Manfro, Jair Jesus Mari, Helena Brentani, Rodrigo Grassi-Oliveira, Elisa Brietzke, Euripedes Constantino Miguel, Luis Augusto Rohde, João Ricardo Sato, Rodrigo Affonseca Bressan, Sintia Iole Belangero
Investigating major depressive disorder (MDD) in childhood and adolescence can help reveal the relative contributions of genetic and environmental factors to MDD, since early stages of disease have less influence of illness exposure. Thus, we investigated the mRNA expression of 12 genes related to the hypothalamic-pituitary-adrenal (HPA) axis, inflammation, neurodevelopment and neurotransmission in the blood of children and adolescents with MDD and tested whether a history of childhood maltreatment (CM) affects MDD through gene expression...
March 22, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28383945/utilizing-the-icf-to-understand-depressive-symptomology-in-multiple-sclerosis-an-exploratory-systematic-review
#18
Diana Dorstyn, Rebecca Black, Elias Mpofu, Ian Kneebone
PURPOSE: Acceptance of the International Classification of Functioning, Disability and Health (ICF) in research and clinical practice has been delayed, despite its multiperspective approach to health measurement. This review utilized the ICF to examine evidence on the associations between depressive symptoms and psychosocial functioning in a patient cohort: multiple sclerosis (MS). RESEARCH METHOD: Forty-nine studies, involving 7,548 adults with relapsing or progressive forms of MS, were quantitatively evaluated...
April 6, 2017: Rehabilitation Psychology
https://www.readbyqxmd.com/read/28383345/availability-of-foodborne-illness-reporting-mechanisms-for-the-public-on-local-health-department-web-sites
#19
Jenine K Harris, Roger Wong, Megan G Matthew, Raed Mansour
CONTEXT: Foodborne illness is a serious and preventable public health problem, with high health and economic tolls in the United States. Local governments play an important role in food safety, with local health departments (LHDs) responsible for licensing and inspecting restaurants. Foodborne illness complaints from the public result in identification of more serious and critical food safety violations than regularly scheduled inspections; however, few people report foodborne illness...
April 4, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28377522/human-health-alters-the-sustainability-of-fishing-practices-in-east-africa
#20
Kathryn J Fiorella, Erin M Milner, Charles R Salmen, Matthew D Hickey, Dan O Omollo, Abdi Odhiambo, Brian Mattah, Elizabeth A Bukusi, Lia C H Fernald, Justin S Brashares
Understanding feedbacks between human and environmental health is critical for the millions who cope with recurrent illness and rely directly on natural resources for sustenance. Although studies have examined how environmental degradation exacerbates infectious disease, the effects of human health on our use of the environment remains unexplored. Human illness is often tacitly assumed to reduce human impacts on the environment. By this logic, ill people reduce the time and effort that they put into extractive livelihoods and, thereby, their impact on natural resources...
April 4, 2017: Proceedings of the National Academy of Sciences of the United States of America
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