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https://www.readbyqxmd.com/read/29150900/genetic-overlap-between-epilepsy-and-schizophrenia-evidence-from-cross-phenotype-analysis-in-hong-kong-chinese-population
#1
Hongsheng Gui, Miaoxin Li, Pak C Sham, Larry Baum, Patrick Kwan, Stacey S Cherny
Epilepsy and schizophrenia are common and typical neurological or mental illness respectively, and sometimes they comorbid in the same patients, however the underlying genetic relationship between the two brain diseases is still not fully understood. To investigate the possible genetic contribution to their comorbidity, we performed polygenic risk score (PRS) analyses and genetic correlation estimation so as to identify the overall genetic overlap between the two diseases. The global schizophrenia PRS is strongly associated with schizophrenia phenotype in Hong Kong population (odds ratio = 1...
November 17, 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/29150304/are-the-estrogenic-hormonal-effects-of-environmental-toxins-affecting-small-intestinal-bacterial-and-microfilaria-overgrowth
#2
Edward Lichten
The important role of microfilaria (worms) in human and animal disease remains an area of key disagreement between the naturopathic and allopathic physicians. While microfilaria infections are rampart in undeveloped countries, they rarely rise to identification as a cause of disease in Western countries. New research studies in the diagnosis and treatment of SIBO (Small Intestinal Bacterial Overgrowth) and (IBD) Inflammatory Bowel Diseases of ulcerative colitis, Crohn's Disease and microcytic colitis may make both sides equally correct...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29148670/using-the-national-environmental-assessment-reporting-system-to-enhance-foodborne-illness-outbreak-investigations-in-new-york-city-restaurants
#3
Bailey Matis, Wendy McKelvey, Dan O'Halloran, Faina Stavinsky, Melissa Wong
No abstract text is available yet for this article.
April 2017: Journal of Environmental Health
https://www.readbyqxmd.com/read/29145849/monitoring-so2emission-trends-and-residents-perceived-health-risks-from-pgm-smelting-at-selous-metallurgical-complex-in-zimbabwe
#4
Patrick Gwimbi
BACKGROUND: Persistently high sulphur dioxide (SO2) emissions from platinum group metal (PGM) smelting pose a major threat to communities located around smelters. This paper examined SO2 emission trends, emission regulations and residents' perceived health risks from exposures to such emissions at Selous Metallurgical Complex (SMC) PGM smelting facility in Zimbabwe. METHODS: SO2 data from roof monitoring sites at the smelter furnace were aggregated into annual, quarterly and monthly emission trends from 2008 to 2015...
November 16, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29145815/illness-recognition-and-care-seeking-for-maternal-complications-of-pregnancy-and-birth-in-rural-amhara-and-oromia-regional-states-of-ethiopia
#5
Lynn Sibley, Yared Amare
BACKGROUND: Ethiopia has made steady progress in improving maternal health over the decade, yet mortality remains high. The Maternal and Newborn Health in Ethiopia Partnership (MaNHEP) was a 3.5-year project aimed at developing a community-oriented model to improve maternal and newborn survival in rural Ethiopia. Two years after the project ended, we carried out a case study to explore illness recognition and care seeking for complications of pregnancy and childbirth in the project area...
November 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29144157/the-influence-of-sunlight-exposure-on-hospitalization-in-emergency-psychiatry
#6
Andrea Aguglia, Antonio Borsotti, Francesco Cuniberti, Gianluca Serafini, Mario Amore, Giuseppe Maina
OBJECTIVE: Environmental conditions during early life may affect individual vulnerability to both physiological changes as well as psychiatric conditions, especially in those with a genetic susceptibility. Among all factors, sunlight exposure intensity has a crucial effect on affecting circadian functions high-risk individuals. A potential explanation of this relation is that excessive sunlight exposure is able to impair biological mechanisms, possibly through the dysregulation of serotonin and/or melatonin production/metabolism...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29141785/environmental-adversities-and-psychotic-symptoms-the-impact-of-timing-of-trauma-abuse-and-neglect
#7
Inga Schalinski, Susanne Breinlinger, Vanessa Hirt, Martin H Teicher, Michael Odenwald, Brigitte Rockstroh
BACKGROUND: Trauma and adverse childhood experiences (ACE) occur more often in mental illness, including psychosis, than in the general population. Individuals with psychosis (cases) report a higher number and severity (dose) of adversities than healthy controls. While a dose-dependent increase of adversities has been related to more severe psychopathology, the role of type and timing is still insufficiently understood on the exacerbation of positive and negative psychotic symptoms. Moreover, dissociative symptoms were examined as potential mediator between adversities and severity of psychotic symptoms...
November 13, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29137271/environmental-conditions-differentially-affect-neurobehavioral-outcomes-in-a-mouse-model-of-sepsis-associated-encephalopathy
#8
Mu-Huo Ji, Hui Tang, Dan Luo, Li-Li Qiu, Min Jia, Hong-Mei Yuan, Shan-Wu Feng, Jian-Jun Yang
Brain dysfunction remains a common complication after sepsis development and is an independent risk factor for a poorer prognosis and an increased mortality. Here we tested the hypothesis that the behavioral outcomes after lipopolysaccharides (LPS) administration are exacerbated by an impoverished environment (IE) and alleviated by an enriched environment (EE), respectively. Mice were randomly allocated in a standard environment (SE), an EE, or an IE for 4 weeks after LPS or normal saline (NS) administration...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29135202/direct-from-cdc-ehsb-cdc-takes-action-to-improve-the-reporting-of-environmental-assessment-data-during-foodborne-illness-outbreak-investigations
#9
Erik W Coleman
No abstract text is available yet for this article.
January 2017: Journal of Environmental Health
https://www.readbyqxmd.com/read/29132365/socioeconomic-inequalities-in-under-five-mortality-in-rural-bangladesh-evidence-from-seven-national-surveys-spreading-over-20%C3%A2-years
#10
Asiful Haidar Chowdhury, Syed Manzoor Ahmed Hanifi, Mohammad Nahid Mia, Abbas Bhuiya
BACKGROUND: Socioeconomic inequality in health and mortality remains a disturbing reality across nations including Bangladesh. Inequality drew renewed attention globally. Bangladesh though made impressive progress in health, it makes an interesting case for learning. This paper examined the trends and changing pattern of socioeconomic inequalities in under-five mortality in rural Bangladesh. It also examined whether mother's education had any effect in reducing socioeconomic inequalities...
November 13, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29130470/-the-influence-of-social-stress-on-the-reinforcing-effect-of-ecstasy-under-the-conditioned-place-preference-paradigm-the-role-played-by-age-dose-and-type-of-stress
#11
REVIEW
M P Garcia-Pardo, J E de la Rubia, M A Aguilar
INTRODUCTION: Addiction to drugs is a chronic illness with severe repercussions for those that consume them and to date has no known cure. Psychostimulants, such as ecstasy, are the most widely consumed illegal drugs among adolescents and young adults. AIMS: To describe and to analyse the different variables that can influence the effects of social stress and the reinforcing properties of ecstasy. Likewise, it also seeks to evaluate whether the effects of social stress on conditioned place preference (induced by ecstasy) are similar to those deriving from other psychostimulants, such as cocaine...
November 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/29129043/economic-evaluation-of-environmental-epidemiological-projects-in-national-industrial-complexes
#12
Youngchul Shin
In this economic evaluation of environmental epidemiological monitoring projects, we analyzed the economic feasibility of these projects by determining the social cost and benefit of these projects and conducting a cost/benefit analysis. Here, the social cost was evaluated by converting annual budgets for these research and survey projects into present values. Meanwhile, the societal benefit of these projects was evaluated by using the contingent valuation method to estimate the willingness to pay of residents living in or near industrial complexes...
November 13, 2017: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/29122313/has-the-question-of-e-waste-opened-a-pandora-s-box-an-overview-of-unpredictable-issues-and-challenges
#13
REVIEW
Bouchra Bakhiyi, Sabrina Gravel, Diana Ceballos, Michael A Flynn, Joseph Zayed
Despite regulatory efforts and position papers, electrical and electronic waste (e-waste) remains ill-managed as evidenced by the extremely low rates of proper e-waste recycling (e-recycling) worldwide, ongoing illegal shipments to developing countries and constantly reported human health issues and environmental pollution. The objectives of this review are, first, to expose the complexity of e-waste problems, and then to suggest possible upstream and downstream solutions. Exploring e-waste issues is akin to opening a Pandora's box...
January 2018: Environment International
https://www.readbyqxmd.com/read/29120997/waterborne-disease-outbreaks-associated-with-environmental-and-undetermined-exposures-to-water-united-states-2013-2014
#14
R Paul McClung, David M Roth, Marissa Vigar, Virginia A Roberts, Amy M Kahler, Laura A Cooley, Elizabeth D Hilborn, Timothy J Wade, Kathleen E Fullerton, Jonathan S Yoder, Vincent R Hill
Waterborne disease outbreaks in the United States are associated with a wide variety of water exposures and are reported annually to CDC on a voluntary basis by state and territorial health departments through the National Outbreak Reporting System (NORS). A majority of outbreaks arise from exposure to drinking water (1) or recreational water (2), whereas others are caused by an environmental exposure to water or an undetermined exposure to water. During 2013-2014, 15 outbreaks associated with an environmental exposure to water and 12 outbreaks with an undetermined exposure to water were reported, resulting in at least 289 cases of illness, 108 hospitalizations, and 17 deaths...
November 10, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29116002/ice-associated-norovirus-outbreak-predominantly-caused-by-gii-17-in-taiwan-2015
#15
Hao-Yuan Cheng, Min-Nan Hung, Wan-Chin Chen, Yi-Chun Lo, Ying-Shih Su, Hsin-Yi Wei, Meng-Yu Chen, Yen-Chang Tuan, Hui-Chen Lin, Hsu-Yang Lin, Tsung-Yen Liu, Yu-Ying Wang, Fang-Tzy Wu
BACKGROUND: On 5 March 2015, Taiwan Centers for Disease Control was notified of more than 200 students with gastroenteritis at a senior high school during excursion to Kenting. We conducted an outbreak investigation to identify the causative agent and possible vehicle of the pathogen. METHODS: We conducted a retrospective cohort study by using a structured questionnaire to interview all students for consumed food items during their stay at the resort. Students were defined as a gastroenteritis case while having vomiting or diarrhea after the breakfast on 4 March...
November 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29115288/child-environmental-exposures-to-water-and-sand-at-the-beach-findings-from-studies-of-over-68-000-subjects-at-12-beaches
#16
Stephanie DeFlorio-Barker, Benjamin F Arnold, Elizabeth A Sams, Alfred P Dufour, John M Colford, Steven B Weisberg, Kenneth C Schiff, Timothy J Wade
Swimming and recreating in lakes, oceans, and rivers is common, yet the literature suggests children may be at greater risk of illness following such exposures. These effects might be due to differences in immunity or differing behavioral factors such as poorer hygiene, longer exposures to, and greater ingestion of potentially contaminated water and sand. We pooled data from 12 prospective cohorts (n=68,685) to examine exposures to potentially contaminated media such as beach water and sand among children compared with adults, and conducted a simulation using self-reported time spent in the water and volume of water swallowed per minute by age to estimate the total volume of water swallowed per swimming event by age category...
November 8, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29107574/high-prevalence-of-salmonella-spp-in-wastewater-reused-for-irrigation-assessed-by-molecular-methods
#17
Paula Santiago, Ana Jiménez-Belenguer, Jorge García-Hernández, Rosa Montes Estellés, Manuel Hernández Pérez, M Angeles Castillo López, María Antonia Ferrús, Yolanda Moreno
Salmonella spp. is one of the most important causal agents of food-borne illness in developed countries and its presence in irrigation water poses a risk to public health. Its detection in environmental samples is not easy when culture methods are used, and molecular techniques such as PCR or ribosomal rRNA probe hybridization (Fluorescent in situ Hybridization, FISH) are outstanding alternatives. The aim of this work was to determine the environmental risk due to the presence of Salmonella spp. in wastewater by culture, PCR and FISH...
October 24, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29104863/the-flagellar-regulon-of-legionella-a-review
#18
REVIEW
Sandra Appelt, Klaus Heuner
The Legionella genus comprises more than 60 species. In particular, Legionella pneumophila is known to cause severe illnesses in humans. Legionellaceae are ubiquitous inhabitants of aquatic environments. Some Legionellaceae are motile and their motility is important to move around in habitats. Motility can be considered as a potential virulence factor as already shown for various human pathogens. The genes of the flagellar system, regulator and structural genes, are structured in hierarchical levels described as the flagellar regulon...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29103405/survival-of-neisseria-meningitidis-outside-of-the-host-environmental-effects-and-differences-among-strains
#19
C L Swain, D R Martin, D Sim, T W Jordan, J K Mackichan
Neisseria meningitidis is a gram-negative bacterium that lives as a commensal in the human nasopharynx. Meningococci are generally non-invasive, but can invade the nasopharyngeal epithelia and enter the bloodstream causing life-threatening illnesses. It is generally thought that meningococci do not survive for long outside the host, and that transmission requires relatively close contact between hosts. There are some reports, however, that meningococci can survive drying on surfaces, including glass, plastic and cloth...
November 6, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/29099558/antidepressant-exposure-during-pregnancy-and-risk-of-autism-in-the-offspring-2-do-the-new-studies-add-anything-new
#20
Chittaranjan Andrade
BACKGROUND: During the past year, at least 5 new studies, all observational in design, examined the risk of autism spectrum disorder (ASD) in children exposed to antidepressant medication in utero. These studies had not found inclusion in the many systematic reviews and meta-analyses that had also been published in the past year. METHODS: Noteworthy methods and findings of the new studies are summarized. One of these studies is examined in detail to help the reader understand methodological and conceptual issues that are critical in the field...
September 2017: Journal of Clinical Psychiatry
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