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https://www.readbyqxmd.com/read/27743011/variability-in-spatio-temporal-pattern-of-trapezius-activity-and-coordination-of-hand-arm-muscles-during-a-sustained-repetitive-dynamic-task
#1
Afshin Samani, Divya Srinivasan, Svend Erik Mathiassen, Pascal Madeleine
The spatio-temporal distribution of muscle activity has been suggested to be a determinant of fatigue development. Pursuing this hypothesis, we investigated the pattern of muscular activity in the shoulder and arm during a repetitive dynamic task performed until participants' rating of perceived exertion reached 8 on Borg's CR-10 scale. We collected high-density surface electromyogram (HD-EMG) over the upper trapezius, as well as bipolar EMG from biceps brachii, triceps brachii, deltoideus anterior, serratus anterior, upper and lower trapezius from 21 healthy women...
October 14, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27727120/comparison-of-algorithms-to-quantify-muscle-fatigue-in-upper-limb-muscles-based-on-semg-signals
#2
Lorenz Kahl, Ulrich G Hofmann
This work compared the performance of six different fatigue detection algorithms quantifying muscle fatigue based on electromyographic signals. Surface electromyography (sEMG) was obtained by an experiment from upper arm contractions at three different load levels from twelve volunteers. Fatigue detection algorithms mean frequency (MNF), spectral moments ratio (SMR), the wavelet method WIRM1551, sample entropy (SampEn), fuzzy approximate entropy (fApEn) and recurrence quantification analysis (RQA%DET) were calculated...
October 7, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27679675/effect-of-cyp3a4-genetic-polymorphisms-on-the-genotoxicity-of-4-4-methylene-bis-2-chloroaniline-exposed-workers
#3
Chung-Ching Wang, Wei-Liang Chen, Chia-Ni Hsiung, Sheng-Ta Chiang, Ying-Chuan Wang, Ching-Hui Loh, I-Shen Lin, Hong-I Chen, Saou-Hsing Liou
OBJECTIVES: We investigated the relationship between 4,4'-methylene-bis(2-chloroaniline) (MBOCA) exposure and micronucleus (MN) frequency, and how this association was affected by genetic polymorphism of the cytochrome P450 enzyme (CYP3A4). METHODS: We divided the study population into an exposed group (n=44 with total urine MBOCA ≥20 μg/g creatinine) and a control group (n=47 with total urine MBOCA <20 μg/g creatinine). Lymphocyte MN frequency (MNF) and micronucleated cell (MNC) frequency were measured by the cytokinesis-block MN assay method...
September 27, 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27524022/fabrication-of-robust-antheraea-assama-fibroin-nanofibrous-mat-using-ionic-liquid-for-skin-tissue-engineering
#4
Chandra Mohan Srivastava, Roli Purwar
Electrospinning is an emerging technique used for fabrication of nanofibrous mats for skin tissue engineering applications. The aim of this study centered on fabrication of muga fibroin electrospun mats by using ionic liquid and its characterizations. The muga fibroin extracted from cocoon of Antheraea assama is dissolved in 1-butyl, 3-methyl imidazolium acetate (BMIMAc), a green solvent, to prepare a dope solution for electrospinning. The molecular weight, rheology and structural properties of dope solution are characterized...
November 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27423937/selective-gpr55-antagonism-reduces-chemoresistance-in-cancer-cells
#5
Nagendra S Singh, Michel Bernier, Irving W Wainer
G protein-coupled receptor 55 (GPR55) possesses pro-oncogenic activity and its function can be competitively inhibited with (R,R')-4'-methoxy-1-naphthylfenoterol (MNF) through poorly defined signaling pathways. Here, the anti-tumorigenic effect of MNF was investigated in the human pancreatic cancer cell line, PANC-1, by focusing on the expression of known cancer biomarkers and the expression and function of multidrug resistance (MDR) exporters such as P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP)...
September 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/27421258/intensity-dependent-emg-response-for-the-biceps-brachii-during-sustained-maximal-and-submaximal-isometric-contractions
#6
Joshua C Carr, Travis W Beck, Xin Ye, Nathan P Wages
PURPOSE: There have been recent attempts to characterize the mechanisms associated with fatigue-induced task failure. We compared the time to failure and the corresponding changes in the surface electromyogram (EMG) during sustained maximal and submaximal isometric force tasks. METHODS: EMG activity was measured from the biceps brachii of 18 male participants as they sustained either a maximal or submaximal (60 % MVC) isometric contraction of the dominant elbow flexors until force could not be maintained above 55 % MVC...
September 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27374422/culture-of-domestic-cat-ovarian-tissue-in-vitro-and-in-the-chick-embryo-chorioallantoic-membrane
#7
J M V Vilela, E C R Leonel, L D'Oliveira, R E G Paiva, A L Miranda-Vilela, C A Amorim, A Pic-Taylor, C M Lucci
In vitro culture and transplantation procedures are essential protocols employed in the evaluation of ovarian follicle survival and development. Culture in the chorioallantoic membrane (CAM) of chick embryos is an intermediate method that provides important follicle development information and has not been tested for cat ovaries to date. The aim of this study was to investigate if in vitro and CAM culture could be used as short-term systems to study cat ovarian tissue development. The ovaries of eight cats were dissected into 3-mm(3) cubes, cultured in vitro and in CAM for up to 5 days, and stained with hematoxylin-eosin and Gomori trichrome...
October 15, 2016: Theriogenology
https://www.readbyqxmd.com/read/27358814/novel-three-dimensional-position-analysis-of-the-mandibular-foramen-in-patients-with-skeletal-class-iii-mandibular-prognathism
#8
Sang-Hoon Kang, Yeon-Ho Kim, Yu-Jin Won, Moon-Key Kim
PURPOSE: To analyze the relative position of the mandibular foramina (MnFs) in patients diagnosed with skeletal class III malocclusion. MATERIALS AND METHODS: Computed tomography (CT) images were collected from 85 patients. The vertical lengths of each anatomic point from the five horizontal planes passing through the MnF were measured at the coronoid process, sigmoid notch, condyle, and the gonion. The distance from the anterior ramus point to the posterior ramus point on the five horizontal planes was designated the anteroposterior horizontal distance of the ramus for each plane...
June 2016: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/27160792/antiferromagnetic-ordering-in-mnf-salen
#9
Erik Čižmár, Olivia N Risset, Tong Wang, Martin Botko, Akhil R Ahir, Matthew J Andrus, Ju-Hyun Park, Khalil A Abboud, Daniel R Talham, Mark W Meisel, Stuart E Brown
Antiferromagnetic order at [Formula: see text] K has been identified in Mn(III)F(salen), salen  =  H14C16N2O2, an S  =  2 linear-chain system. Using single crystals, specific heat studies performed in magnetic fields up to 9 T revealed the presence of a field-independent cusp at the same temperature where (1)H NMR studies conducted at 42 MHz observed dramatic changes in the spin-lattice relaxation time, T 1, and in the linewidths. Low-field (less than 0.1 T) magnetic susceptibility studies of single crystals and randomly-arranged microcrystalline samples reveal subtle features associated with the transition...
June 15, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27148820/absent-in-melanoma-2-aim2-limits-pro-inflammatory-cytokine-transcription-in-cardiomyocytes-by-inhibiting-stat1-phosphorylation
#10
Antonia Furrer, Michael O Hottiger, Alan Valaperti
Interferon (IFN)-γ is highly upregulated during heart inflammation and enhances the production of pro-inflammatory cytokines. Absent in Melanoma 2 (AIM2) is an IFN-inducible protein implicated as a component of the inflammasome. Here we seek to determine the role of AIM2 during inflammation in cardiac cells. We found that the presence of AIM2, but not of the other inflammasome components Nod-like receptor (NLR) NLRP3 or NLRC4, specifically limited the transcription of the pro-inflammatory cytokines interleukin (IL)-6, IP-10, and tumor necrosis factor (TNF)-α in HL-1 mouse cardiomyocytes stimulated with IFN-γ and lipopolysaccharides (LPS)...
June 2016: Molecular Immunology
https://www.readbyqxmd.com/read/26991198/antiferromagnetic-spin-seebeck-effect
#11
Stephen M Wu, Wei Zhang, Amit Kc, Pavel Borisov, John E Pearson, J Samuel Jiang, David Lederman, Axel Hoffmann, Anand Bhattacharya
We report on the observation of the spin Seebeck effect in antiferromagnetic MnF_{2}. A device scale on-chip heater is deposited on a bilayer of MnF_{2} (110) (30  nm)/Pt (4 nm) grown by molecular beam epitaxy on a MgF_{2} (110) substrate. Using Pt as a spin detector layer, it is possible to measure the thermally generated spin current from MnF_{2} through the inverse spin Hall effect. The low temperature (2-80 K) and high magnetic field (up to 140 kOe) regime is explored. A clear spin-flop transition corresponding to the sudden rotation of antiferromagnetic spins out of the easy axis is observed in the spin Seebeck signal when large magnetic fields (>9  T) are applied parallel to the easy axis of the MnF_{2} thin film...
March 4, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/26968423/cutaneous-metastasis-of-pleomorphic-liposarcoma-to-the-scalp-an-elusive-diagnosis
#12
JiaDe Yu, Olayemi Sokumbi
Liposarcomas are one of the most common sarcomas arising in the extremities of the elderly. Various subtypes of liposarcomas include well-differentiated liposarcomas, dedifferentiated liposarcomas, myxoid liposarcomas and pleomorphic liposarcomas. Pleomorphic liposarcomas are the rarest subtype and have the highest malignant potential compared with the other subtypes of liposarcomas. Metastases to internal organs are common but cutaneous metastasis is very rare with only few cases in the literature. We present a patient with a known diagnosis of stage IV metastatic liposarcoma who presented to our clinic with a rapidly growing nodule on the scalp...
June 2016: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/26906950/immunohistochemical-expression-of-keratins-6-7-8-14-16-18-19-and-mnf-116-pancytokeratin-in-primary-and-metastatic-melanoma-of-the-head-and-neck
#13
Rima A Safadi, Dima H Bader, Niveen I Abdullah, Maher A Sughayer
OBJECTIVE: To investigate the immunohistochemical expression (IHCE) of selected keratins in primary cutaneous and mucosal melanoma (pM), and metastatic melanoma (metsM) of the head and neck and to compare their expression to a group of undifferentiated/poorly differentiated tumors of the same anatomic region. STUDY DESIGN: IHCE of K6, K7, K8, K14, K16, K18, and K19 were studied in 29 melanomas and 70 cases of non-melanoma tumors of the same anatomic region (neuroendocrine carcinoma, neuroblastoma, olfactory neuroblastoma, sinonasal undifferentiated carcinoma, undifferentiated nasopharyngeal carcinoma, anaplastic large cell lymphoma, poorly differentiated squamous cell carcinoma (PDSCC), and Ewing sarcoma)...
May 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/26887581/comparative-study-of-wavelet-denoising-in-myoelectric-control-applications
#14
Tanu Sharma, Karan Veer
Here, the wavelet analysis has been investigated to improve the quality of myoelectric signal before use in prosthetic design. Effective Surface Electromyogram (SEMG) signals were estimated by first decomposing the obtained signal using wavelet transform and then analysing the decomposed coefficients by threshold methods. With the appropriate choice of wavelet, it is possible to reduce interference noise effectively in the SEMG signal. However, the most effective wavelet for SEMG denoising is chosen by calculating the root mean square value and signal power values...
2016: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/26884312/mia-paca-2-and-panc-1-pancreas-ductal-adenocarcinoma-cell-lines-with-neuroendocrine-differentiation-and-somatostatin-receptors
#15
Rui Gradiz, Henriqueta C Silva, Lina Carvalho, Maria Filomena Botelho, Anabela Mota-Pinto
Studies using cell lines should always characterize these cells to ensure that the results are not distorted by unexpected morphological or genetic changes possibly due to culture time or passage number. Thus, the aim of this study was to describe those MIA PaCa-2 and PANC-1 cell line phenotype and genotype characteristics that may play a crucial role in pancreatic cancer therapeutic assays, namely neuroendocrine chemotherapy and peptide receptor radionuclide therapy. Epithelial, mesenchymal, endocrine and stem cell marker characterization was performed by immunohistochemistry and flow cytometry, and genotyping by PCR, gene sequencing and capillary electrophoresis...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26857518/electromyographic-evaluation-of-countermeasures-during-the-terrestrial-simulation-of-interplanetary-spaceflight-in-mars500-project
#16
A Meigal, E Fomina
The efficiency of six countermeasures (CM) for muscle atrophy was compared over 520 days of confinement during the terrestrial simulation of round space flight to Mars using surface electromyography (sEMG). Three of CM were cyclic exercises (a motor-driven and leg-driven treadmill, cycle ergometer), resistive exercises (the multifunctional dynamometer for space-MDS, and expanders), and vibration platform. Each of CM was applied for each crew member (n=6) once over the experiment, for 70 days in a row, in prescribed order...
March 2016: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/26822295/highly-flexible-self-powered-sensors-based-on-printed-circuit-board-technology-for-human-motion-detection-and-gesture-recognition
#17
Yiin-Kuen Fuh, Hsi-Chun Ho
In this paper, we demonstrate a new integration of printed circuit board (PCB) technology-based self-powered sensors (PSSs) and direct-write, near-field electrospinning (NFES) with polyvinylidene fluoride (PVDF) micro/nano fibers (MNFs) as source materials. Integration with PCB technology is highly desirable for affordable mass production. In addition, we systematically investigate the effects of electrodes with intervals in the range of 0.15 mm to 0.40 mm on the resultant PSS output voltage and current...
March 4, 2016: Nanotechnology
https://www.readbyqxmd.com/read/26773021/integration-to-implementation-and-the-micronutrient-forum-a-coordinated-approach-for-global-nutrition-case-study-application-safety-and-effectiveness-of-iron-interventions
#18
REVIEW
Daniel J Raiten, Lynnette M Neufeld, Luz-Maria De-Regil, Sant-Rayn Pasricha, Ian Darnton-Hill, Richard Hurrell, Laura E Murray-Kolb, K Madhavan Nair, Terry Wefwafwa, Roland Kupka, Modou Cheyassin Phall, Fayrouz A Sakr Ashour
Paramount among the challenges to our ability to address the role of food and nutrition in health promotion and disease prevention is how to design and implement context-specific interventions and guidance. The Integration to Effective Implementation (I-to-I) concept is intended to address the complexities of the global health context through engagement of the continuum of stakeholders involved in the food and nutrition enterprise. The 2014 Micronutrient Forum (MNF) Global Conference held in Addis Ababa, Ethiopia, in June 2014 offered the opportunity to apply the I-to-I approach with the use of current concerns about the safety and effectiveness of interventions to prevent and treat iron deficiency (ID) as a case study...
January 2016: Advances in Nutrition
https://www.readbyqxmd.com/read/26736307/muscular-fatigue-detection-using-semg-in-dynamic-contractions
#19
Diana R Bueno, J M Lizano, L Montano
In this work we have studied different indicators of muscle fatigue from the electrical signal produced by the muscles when contract (sEMG or EMG: surface electromyography): Mean Frequency of the power spectrum (MNF), Median Frequency (Fmed), Dimitrov Spectral Index (FInsm5), Root Mean Square (RMS), and Zerocrossing (ZC). The most reliable features are selected to develop a detection algorithm that estimates muscle fatigue. The approach used in the algorithm is probabilistic and is based on the technique of Gaussian Mixture Model (GMM)...
August 2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/26601395/-the-change-detection-of-high-spatial-resolution-remotely-sensed-imagery-based-on-ob-hmad-algorithm-and-spectral-features
#20
Qiang Chen, Yun-hao Chen, Wei-guo Jiang
The high spatial resolution remotely sensed imagery has abundant detailed information of earth surface, and the multi-temporal change detection for the high resolution remotely sensed imagery can realize the variations of geographical unit. In terms of the high spatial resolution remotely sensed imagery, the traditional remote sensing change detection algorithms have obvious defects. In this paper, learning from the object-based image analysis idea, we proposed a semi-automatic threshold selection algorithm named OB-HMAD (object-based-hybrid-MAD), on the basis of object-based image analysis and multivariate alternative detection algorithm (MAD), which used the spectral features of remotely sensed imagery into the field of object-based change detection...
June 2015: Guang Pu Xue Yu Guang Pu Fen Xi, Guang Pu
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