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https://www.readbyqxmd.com/read/29107837/power-frequency-spectrum-analysis-of-surface-emg-signals-of-upper-limb-muscles-during-elbow-flexion-a-comparison-between-healthy-subjects-and-stroke-survivors
#1
Silvija Angelova, Simeon Ribagin, Rositsa Raikova, Ivanka Veneva
After a stroke, motor units stop working properly and large, fast-twitch units are more frequently affected. Their impaired functions can be investigated during dynamic tasks using electromyographic (EMG) signal analysis. The aim of this paper is to investigate changes in the parameters of the power/frequency function during elbow flexion between affected, non-affected, and healthy muscles. Fifteen healthy subjects and ten stroke survivors participated in the experiments. Electromyographic data from 6 muscles of the upper limbs during elbow flexion were filtered and normalized to the amplitudes of EMG signals during maximal isometric tasks...
October 31, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29060510/comparison-of-electrohysterogram-characteristics-during-uterine-contraction-and-non-contraction-during-labor
#2
Zhihui Liu, Dongmei Hao, Lei Zhang, Juntao Liu, Xiya Zhou, Lin Yang, Yimin Yang, Xuwen Li, Song Zhang, Dingchang Zheng
Uterine contraction is one of the most important indication in the labor progression. Electrohysterogram (EHG) is a promising method for monitoring uterine contraction and discriminating efficient and inefficient contractions. This study aims to analyze the difference of EHG signals between two groups. EHG signals are recorded with abdominal electrodes from 20 pregnant women, including 10 in term labor group and 10 in non-labor group. Typical linear and nonlinear characteristics of EHG signals, including root mean square (RMS), peak frequency (PF), median frequency (MDF), mean frequency (MNF), parameters from wavelet decomposition (W4, W5) and time reversibility (Tr) are extracted...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28894269/effect-of-mesoporous-nano-water-reservoir-on-mr-relaxivity
#3
Palani Sharmiladevi, Viswanathan Haribabu, Koyeli Girigoswami, Abubacker Sulaiman Farook, Agnishwar Girigoswami
In the present work, an attempt was made to engineer a mesoporous silica coated magnetic nanoparticles (MNF@mSiO2) for twin mode contrast in magnetic resonance imaging (MRI) with reduced toxicity. Superparamagnetic manganese ferrite nanoparticles were synthesized with variable mesoporous silica shell thickness to control the water molecules interacting with metal oxide core. 178 nm was the optimum hydrodynamic diameter of mesoporous ferrite core-shell nanoparticles that showed maximum longitudinal relaxation time (T1) and transverse relaxation time (T2) in MRI due to the storage of water molecules in mesoporous silica coating...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28886079/associations-between-lower-limb-muscle-activation-and-knee-flexion-in-post-stroke-individuals-a-study-on-the-stance-to-swing-phases-of-gait
#4
Wei Wang, Ke Li, Shouwei Yue, Cuiping Yin, Na Wei
Reduced knee flexion is a leading feature of post-stroke gait, but the causes have not been well understood. The purpose of this study was to investigate the relationship between the knee flexion and the lower-limb muscle activation within the stance-to-swing phases of gait cycle in the post-stroke hemiplegic patients. Ten stroke patients and 10 age- and gender-matched healthy subjects participated in the experiment. The lower-limb kinematic signals and the surface electromyography (sEMG) signals of the left and right rectus femoris (RF), biceps femoris (BF) and lateral gastrocnemius (GS) were recorded during walking...
2017: PloS One
https://www.readbyqxmd.com/read/28741686/gpr55-receptor-antagonist-decreases-glycolytic-activity-in-panc-1-pancreatic-cancer-cell-line-and-tumor-xenografts
#5
Michel Bernier, Jonathan Catazaro, Nagendra S Singh, Artur Wnorowski, Anna Boguszewska-Czubara, Krzysztof Jozwiak, Robert Powers, Irving W Wainer
The Warburg effect is a predominant metabolic pathway in cancer cells characterized by enhanced glucose uptake and its conversion to l-lactate and is associated with upregulated expression of HIF-1α and activation of the EGFR-MEK-ERK, Wnt-β-catenin, and PI3K-AKT signaling pathways. (R,R')-4'-methoxy-1-naphthylfenoterol ((R,R')-MNF) significantly reduces proliferation, survival, and motility of PANC-1 pancreatic cancer cells through inhibition of the GPR55 receptor. We examined (R,R')-MNF's effect on glycolysis in PANC-1 cells and tumors...
November 15, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28731769/first-principles-prediction-of-spin-polarized-multiple-dirac-rings-in-manganese-fluoride
#6
Yalong Jiao, Fengxian Ma, Chunmei Zhang, John Bell, Stefano Sanvito, Aijun Du
Spin-polarized materials with Dirac features have sparked great scientific interest due to their potential applications in spintronics. But such a type of structure is very rare and none has been fabricated. Here, we investigate the already experimentally synthesized manganese fluoride (MnF_{3}) as a novel spin-polarized Dirac material by using first-principles calculations. MnF_{3} exhibits multiple Dirac cones in one spin orientation, while it behaves like a large gap semiconductor in the other spin channel...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28692691/extracting-time-frequency-feature-of-single-channel-vastus-medialis-emg-signals-for-knee-exercise-pattern-recognition
#7
Yi Zhang, Peiyang Li, Xuyang Zhu, Steven W Su, Qing Guo, Peng Xu, Dezhong Yao
The EMG signal indicates the electrophysiological response to daily living of activities, particularly to lower-limb knee exercises. Literature reports have shown numerous benefits of the Wavelet analysis in EMG feature extraction for pattern recognition. However, its application to typical knee exercises when using only a single EMG channel is limited. In this study, three types of knee exercises, i.e., flexion of the leg up (standing), hip extension from a sitting position (sitting) and gait (walking) are investigated from 14 healthy untrained subjects, while EMG signals from the muscle group of vastus medialis and the goniometer on the knee joint of the detected leg are synchronously monitored and recorded...
2017: PloS One
https://www.readbyqxmd.com/read/28622605/flexible-nanofilms-coated-with-aligned-piezoelectric-microfibers-preserve-the-contractility-of-cardiomyocytes
#8
P José Gouveia, S Rosa, L Ricotti, B Abecasis, H V Almeida, L Monteiro, J Nunes, F Sofia Carvalho, M Serra, S Luchkin, A Leonidovitch Kholkin, P Marques Alves, P Jorge Oliveira, R Carvalho, A Menciassi, R Pires das Neves, L Silva Ferreira
The use of engineered cardiac tissue for high-throughput drug screening/toxicology assessment remains largely unexplored. Here we propose a scaffold that mimics aspects of cardiac extracellular matrix while preserving the contractility of cardiomyocytes. The scaffold is based on a poly(caprolactone) (PCL) nanofilm with magnetic properties (MNF, standing for magnetic nanofilm) coated with a layer of piezoelectric (PIEZO) microfibers of poly(vinylidene fluoride-trifluoroethylene) (MNF+PIEZO). The nanofilm creates a flexible support for cell contraction and the aligned PIEZO microfibers deposited on top of the nanofilm creates conditions for cell alignment and electrical stimulation of the seeded cells...
September 2017: Biomaterials
https://www.readbyqxmd.com/read/28505208/neuromuscular-function-of-the-quadriceps-muscle-during-isometric-maximal-submaximal-and-submaximal-fatiguing-voluntary-contractions-in-knee-osteoarthrosis-patients
#9
Anett Mau-Moeller, Robert Jacksteit, Mario Jackszis, Frank Feldhege, Matthias Weippert, Wolfram Mittelmeier, Rainer Bader, Ralf Skripitz, Martin Behrens
INTRODUCTION: Knee osteoarthrosis (KOA) is commonly associated with a dysfunction of the quadriceps muscle which contributes to alterations in motor performance. The underlying neuromuscular mechanisms of muscle dysfunction are not fully understood. The main objective of this study was to analyze how KOA affects neuromuscular function of the quadriceps muscle during different contraction intensities. MATERIALS AND METHODS: The following parameters were assessed in 20 patients and 20 healthy controls: (i) joint position sense, i...
2017: PloS One
https://www.readbyqxmd.com/read/28495590/concurrent-activation-of-%C3%AE-2-adrenergic-receptor-and-blockage-of-gpr55-disrupts-pro-oncogenic-signaling-in-glioma-cells
#10
Artur Wnorowski, Justyna Such, Rajib K Paul, Robert P Wersto, Fred E Indig, Krzysztof Jozwiak, Michel Bernier, Irving W Wainer
Activation of β2-adrenergic receptor (β2AR) and deorphanized GPR55 has been shown to modulate cancer growth in diverse tumor types in vitro and in xenograft models in vivo. (R,R')-4'-methoxy-1-naphthylfenoterol [(R,R')-MNF] is a bivalent compound that agonizes β2AR but inhibits GPR55-mediated pro-oncogenic responses. Here, we investigated the molecular mechanisms underlying the anti-tumorigenic effects of concurrent β2AR activation and GPR55 blockade in C6 glioma cells using (R,R')-MNF as a marker ligand...
August 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28484760/comparison-of-nucleophilic-and-radical-based-routes-to-the-formation-of-manganese-main-group-element-single-bonds
#11
Douglas W Agnew, Curtis E Moore, Arnold L Rheingold, Joshua S Figueroa
Using the stable metalloradical Mn(CO)3(CNAr(Dipp2))2, we report the formation of manganese-main group complexes via the single-electron functionalization of main group halides. The reactions occur in a simple 1 : 1 stoichiometry, and demonstrate the utility of using stable open-shelled organometallics as precursors for metal-main group compounds. This has enabled the preparation of manganese complexes bearing terminal -EXn substituents, as shown through the isolation of Mn(SnCl)(CO)3(CNAr(Dipp2))2 and Mn(BiCl2)(CO)3(CNAr(Dipp2))2 from SnCl2 and BiCl3, respectively...
May 9, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28448720/mosaic-neurofibromatosis-type-1-in-children-a-single-institution-experience
#12
Irene Lara-Corrales, Mitra Moazzami, Maria Teresa García-Romero, Elena Pope, Patricia Parkin, Andrea Shugar, Peter Kannu
BACKGROUND: Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder caused by loss-of-function mutation in the NF1 gene. Segmental or mosaic NF1 (MNF) is an uncommon presentation of the NF1 result of postzygotic mutations that present with subtle localised clinical findings. OBJECTIVES: Our study's objectives were to describe the clinical characteristics of children with MNF. METHODS: We conducted a cross-sectional study of children diagnosed with MNF at the Hospital for Sick Children in Toronto, Canada, from January 1992 to September 2012...
April 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28289825/the-highly-bioactive-molecule-and-signal-substance-6-formylindolo-3-2-b-carbazole-ficz-plays-bi-functional-roles-in-cell-growth-and-apoptosis-in-vitro
#13
Afshin Mohammadi-Bardbori, Farzaneh Bastan, Amin-Reza Akbarizadeh
The maintenance of cellular homeostasis is a complex process that is governed by the receipt of prototypical growth and death signals. The endogenous functions of aryl hydrocarbon receptor (AHR) in cellular homeostasis are not well understood. We aimed to establish whether the disturbance of endogenously activated AHR can influence cell growth, and if so, what mechanism(s) are involved. Cell growth was measured in mouse hepatoma Hepa-1 wild-type and cytochrome P4501A1 (CYP1A1)-deficient c37 cells. In other sets of experiments, HepG2 cells were exposed to different doses of FICZ (0...
March 13, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28269457/estimation-of-muscle-fatigue-by-ratio-of-mean-frequency-to-average-rectified-value-from-surface-electromyography
#14
Jeffry Bonar Fernando, Mototaka Yoshioka, Jun Ozawa
A new method to estimate muscle fatigue quantitatively from surface electromyography (EMG) is proposed. The ratio of mean frequency (MNF) to average rectified value (ARV) is used as the index of muscle fatigue, and muscle fatigue is detected when MNF/ARV falls below a pre-determined or pre-calculated baseline. MNF/ARV gives larger distinction between fatigued muscle and non-fatigued muscle. Experiment results show the effectiveness of our method in estimating muscle fatigue more correctly compared to conventional methods...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268659/comparison-of-mean-frequency-and-median-frequency-in-evaluating-muscle-fiber-type-selection-in-varying-gait-speed-across-healthy-young-adult-individuals
#15
C K Chan, G Fu Timothy, C H Yeow
The preferential slow and fast twitches fiber involvement in varying gait speed has not been thoroughly investigated. Attempt to classify fiber type in changing speed should be closely investigated and scrutinized as the histochemical-related experiments are cumbersome and time consuming. In addressing this issue, electromyography (EMG) is utilized to extract the muscle fiber type features by altering the muscle fatigue indices, namely mean frequency (MNF) and median frequency (MDF). Recently, there are no universal indices to determine the muscle type...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227707/estimation-of-muscle-fatigue-by-ratio-of-mean-frequency-to-average-rectified-value-from-surface-electromyography
#16
Jeffry Bonar Fernando, Mototaka Yoshioka, Jun Ozawa, Jeffry Bonar Fernando, Mototaka Yoshioka, Jun Ozawa, Mototaka Yoshioka, Jeffry Bonar Fernando, Jun Ozawa
A new method to estimate muscle fatigue quantitatively from surface electromyography (EMG) is proposed. The ratio of mean frequency (MNF) to average rectified value (ARV) is used as the index of muscle fatigue, and muscle fatigue is detected when MNF/ARV falls below a pre-determined or pre-calculated baseline. MNF/ARV gives larger distinction between fatigued muscle and non-fatigued muscle. Experiment results show the effectiveness of our method in estimating muscle fatigue more correctly compared to conventional methods...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226843/comparison-of-mean-frequency-and-median-frequency-in-evaluating-muscle-fiber-type-selection-in-varying-gait-speed-across-healthy-young-adult-individuals
#17
C K Chan, G Fu Timothy, C H Yeow, C K Chan, G Fu Timothy, C H Yeow, C K Chan, C H Yeow
The preferential slow and fast twitches fiber involvement in varying gait speed has not been thoroughly investigated. Attempt to classify fiber type in changing speed should be closely investigated and scrutinized as the histochemical-related experiments are cumbersome and time consuming. In addressing this issue, electromyography (EMG) is utilized to extract the muscle fiber type features by altering the muscle fatigue indices, namely mean frequency (MNF) and median frequency (MDF). Recently, there are no universal indices to determine the muscle type...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28126654/an-explorative-chemometric-approach-applied-to-hyperspectral-images-for-the-study-of-illuminated-manuscripts
#18
Emilio Catelli, Lise Lyngsnes Randeberg, Bjørn Kåre Alsberg, Kidane Fanta Gebremariam, Silvano Bracci
Hyperspectral imaging (HSI) is a fast non-invasive imaging technology recently applied in the field of art conservation. With the help of chemometrics, important information about the spectral properties and spatial distribution of pigments can be extracted from HSI data. With the intent of expanding the applications of chemometrics to the interpretation of hyperspectral images of historical documents, and, at the same time, to study the colorants and their spatial distribution on ancient illuminated manuscripts, an explorative chemometric approach is here presented...
April 15, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28067522/development-of-a-postcolumn-infused-internal-standard-liquid-chromatography-mass-spectrometry-method-for-quantitative-metabolomics-studies
#19
Hsiao-Wei Liao, Guan-Yuan Chen, Ming-Shiang Wu, Wei-Chih Liao, Ching-Hung Lin, Ching-Hua Kuo
Quantitative metabolomics has become much more important in clinical research in recent years. Individual differences in matrix effects (MEs) and the injection order effect are two major factors that reduce the quantification accuracy in liquid chromatography-electrospray ionization-mass spectrometry-based (LC-ESI-MS) metabolomics studies. This study proposed a postcolumn infused-internal standard (PCI-IS) combined with a matrix normalization factor (MNF) strategy to improve the analytical accuracy of quantitative metabolomics...
February 3, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28040500/a-modification-of-nissen-fundoplication-improves-patients-outcome-and-may-reduce-procedure-related-failure-rate
#20
Romeo Bardini, Sabrina Rampado, Renato Salvador, Lisa Zanatta, Imerio Angriman, Silvia Degasperi, Angelica Ganss, Edoardo Savarino
BACKGROUND: Laparoscopic anti-reflux surgery has a failure rate of 10-20%. We aimed to investigate whether a modification of Nissen fundoplication (MNF) may improve patients' outcome and reduce failure rate. MATERIALS & METHODS: We prospectively compared 40 consecutive patients with gastroesophageal reflux disease who underwent anti-reflux surgery: 20 Nissen fundoplication (NF) and 20 the MNF approach. Eight cases in the MNF group needed redo surgery. The MNF consisted in suturing the esophagus to the diaphragmatic crura on each side by means of 4 non-absorbable stitches and in fixing the upper stitch of the valve to diaphragm...
February 2017: International Journal of Surgery
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