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https://www.readbyqxmd.com/read/28721057/safety-tolerability-and-risks-associated-with-first-and-second-generation-antipsychotics-a-state-of-the-art-clinical-review
#1
REVIEW
Marco Solmi, Andrea Murru, Isabella Pacchiarotti, Juan Undurraga, Nicola Veronese, Michele Fornaro, Brendon Stubbs, Francesco Monaco, Eduard Vieta, Mary V Seeman, Christoph U Correll, André F Carvalho
Since the discovery of chlorpromazine (CPZ) in 1952, first-generation antipsychotics (FGAs) have revolutionized psychiatric care in terms of facilitating discharge from hospital and enabling large numbers of patients with severe mental illness (SMI) to be treated in the community. Second-generation antipsychotics (SGAs) ushered in a progressive shift from the paternalistic management of SMI symptoms to a patient-centered approach, which emphasized targets important to patients - psychosocial functioning, quality of life, and recovery...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28720167/recovery-from-dsm-iv-post-traumatic-stress-disorder-in-the-who-world-mental-health-surveys
#2
A J Rosellini, H Liu, M V Petukhova, N A Sampson, S Aguilar-Gaxiola, J Alonso, G Borges, R Bruffaerts, E J Bromet, G de Girolamo, P de Jonge, J Fayyad, S Florescu, O Gureje, J M Haro, H Hinkov, E G Karam, N Kawakami, K C Koenen, S Lee, J P Lépine, D Levinson, F Navarro-Mateu, B D Oladeji, S O'Neill, B-E Pennell, M Piazza, J Posada-Villa, K M Scott, D J Stein, Y Torres, M C Viana, A M Zaslavsky, R C Kessler
BACKGROUND: Research on post-traumatic stress disorder (PTSD) course finds a substantial proportion of cases remit within 6 months, a majority within 2 years, and a substantial minority persists for many years. Results are inconsistent about pre-trauma predictors. METHODS: The WHO World Mental Health surveys assessed lifetime DSM-IV PTSD presence-course after one randomly-selected trauma, allowing retrospective estimates of PTSD duration. Prior traumas, childhood adversities (CAs), and other lifetime DSM-IV mental disorders were examined as predictors using discrete-time person-month survival analysis among the 1575 respondents with lifetime PTSD...
July 19, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28714841/bifidobacterium-apri-sp-nov-a-thermophilic-actinobacterium-isolated-from-the-digestive-tract-of-wild-pigs-sus-scrofa
#3
R Pechar, J Killer, H Salmonová, M Geigerová, R Švejstil, P Švec, I Sedláček, V Rada, O Benada
Fresh samples of intestinal contents of three wild pigs originating from the Central Bohemia region were examined for the presence of bifidobacterial strains. During the study, we isolated many fructose-6-phosphate phosphoketolase-positive, strictly anaerobic, irregular rod-shaped bacterial isolates. Three of them were preliminarily identified as representing a novel species of the genus Bifidobacterium because their 16S rRNA gene sequence similarity with the closest relatives of thermophilic bifidobacteria (Bifidobacterium boum DSM 20432T, Bifidobacterium thermophilum DSM 20210T, Bifidobacterium thermacidophilumsubsp...
July 17, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28713344/outer-membrane-proteome-of-veillonella-parvula-a-diderm-firmicute-of-the-human-microbiome
#4
Daniel I Poppleton, Magalie Duchateau, Véronique Hourdel, Mariette Matondo, Jennifer Flechsler, Andreas Klingl, Christophe Beloin, Simonetta Gribaldo
Veillonella parvula is a biofilm-forming commensal found in the lungs, vagina, mouth, and gastro-intestinal tract of humans, yet it may develop into an opportunistic pathogen. Furthermore, the presence of Veillonella has been associated with the development of a healthy immune system in infants. Veillonella belongs to the Negativicutes, a diverse clade of bacteria that represent an evolutionary enigma: they phylogenetically belong to Gram-positive (monoderm) Firmicutes yet maintain an outer membrane (OM) with lipopolysaccharide similar to classic Gram-negative (diderm) bacteria...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28703949/psychotherapy-alone-and-combined-with-medication-as-treatments-for-bipolar-ii-depression-a-randomized-controlled-trial
#5
Holly A Swartz, Paola Rucci, Michael E Thase, Meredith Wallace, Elisa Carretta, Karen L Celedonia, Ellen Frank
OBJECTIVE: Bipolar II disorder (BP-II) is associated with marked morbidity and mortality. Quetiapine, the treatment with greatest evidence for efficacy in BP-II depression, is associated with metabolic burden. Psychotherapy, a treatment with few side effects, has not been systematically evaluated in BP-II. This study compared psychotherapy plus placebo to psychotherapy plus pharmacotherapy as treatments for BP-II depression. METHODS: From 2010 to 2015, unmedicated adults (n = 92) with DSM-IV-TR BP-II depression were randomly assigned to weekly sessions of Interpersonal and Social Rhythm Therapy (IPSRT) plus placebo or IPSRT plus quetiapine and followed for 20 weeks...
July 11, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28699880/paenibacillus-konkukensis-sp-nov-isolated-from-animal-feed
#6
Wan-Taek Im, Kwon-Jung Yi, Sang-Suk Lee, Hyung In Moon, Che Ok Jeon, Dong-Woon Kim, Soo-Ki Kim
A Gram-stain-positive, oxidase- and catalase-positive, aerobic, rod-shaped bacterium, designated strain SK-3146T, was isolated from animal feed. Phylogenetic analysis, based on 16S rRNA gene sequence comparisons, revealed that the strain formed a distinct lineage within the genus Paenibacillus that was closely related to Paenibacillusyunnanensis JCM 30953T (98.6 %), Paenibacillusvulneris CCUG 53270T (98.0 %) and Paenibacilluschinjuensis DSM 15045T (96.9 %). Cells were non-motile, endospore-forming and formed milky colonies on NA and R2A agar media...
July 12, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28699865/phaeobacter-porticola-sp-nov-an-antibiotic-producing-bacterium-isolated-from-a-sea-harbour
#7
Sven Breider, Heike M Freese, Cathrin Spröer, Meinhard Simon, Jörg Overmann, Thorsten Brinkhoff
Three heterotrophic, aerobic, brown-pigmented strains, designated P97T, P100 and P104, were isolated from a harbour in the southern North Sea. Phylogenetic analysis of 16S rRNA gene sequences revealed that the isolates are affiliated to the genus Phaeobacter. In silico DNA-DNA hybridization of the genome of strain P97T against those of existing type species indicated that P97T represents a novel species within the genus Phaeobacter, with Phaeobacter inhibens T5T as the closest described organism (29.6 % DNA-DNA relatedness) followed by P...
July 12, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28699860/leucobacter-corticis-sp-nov-isolated-from-symptomatic-bark-of-populus-%C3%A3-euramericana-canker
#8
Yong Li, Wei Fang, Shou-Jiang Xie, Xuqi Yang, Lai-Fa Wang
A Gram-stain-positive, aerobic, non-motile, rod-shaped bacterial strain, designated 2C-7T, was isolated from symptomatic bark of a Populus × euramericana canker. Growth occurred between 10 and 37 °C and between pH 6 and 10, with optimal growth at 30 °C and pH 7.0-8.0. Growth was present under 0-8 % (w/v) salinity conditions (optimum 1-2 %). Growth occurred in the presence of 10 mM chromium (Cr6+). The major fatty acids (≥10 %) of the novel strain were anteiso-C15 : 0, anteiso-C17 : 0 and iso-C16 : 0...
July 12, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28699577/sphingobacteriumsoli-sp-nov-isolated-from-soil
#9
Yu-Song Fu, Firasat Hussain, Neeli Habib, Inam Ullah Khan, Xiao Chu, Yan-Qing Duan, Xiao-Yang Zhi, Xing Chen, Wen-Jun Li
A Gram-stain-negative, strictly aerobic, rod-shaped, non-motile, non-spore-forming bacterial strain, designated YIM X0211T, was isolated from a soil sample of Shiling County, Yunnan Province, south-west China. The new isolate was characterized taxonomically by using a polyphasic approach. The strain grew optimally at 30 °C, at pH 7.0 and with 0-3 % (w/v) NaCl. It was positive for catalase and oxidase but negative for H2S production. Comparative 16S rRNA gene sequence analysis showed that strain YIM X0211T fell within the cluster comprising Sphingobacterium species and clustered with Sphingobacterium mizutaii DSM 11724T (97...
July 12, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28698912/spirosoma-areae-sp-nov-isolated-from-soil
#10
Jun Hyeong Jang, Seho Cha, Dongwook Lee, Sathiyaraj Srinivasan, Weonhwa Jheong, Ha Sung Hwang, Myung Kyum Kim, Taegun Seo
A yellow-colored Gram-negative strain, Arct 1-12(T), was isolated from a soil sample collected in Seoul Women's University, South Korea, and grown on R2A agar at 25 °C. Growth of strain Arct 1-12(T) was observed at a temperature range of 15-30 °C (optimal 25 °C), but not at 4 or 42 °C. The strain tolerated up to 1% NaCl (w/v) and displayed optimal growth in the absence of NaCl. Growth occurred at pH 6.0-9.0 (optimally at pH 7). According to the 16S rRNA gene sequence, the strain is moderately related to Spirosoma spitsbergense DSM 19989(T) (93...
July 12, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28693684/clostridium-tepidum-sp-nov-a-close-relative-of-clostridium-sporogenes-and-clostridium-botulinum-group-i
#11
Anatoly P Dobritsa, Kirthi K Kutumbaka, Kirsten Werner, Martin Wiedmann, Aaron Asmus, Mansour Samadpour
Obligately anaerobic, Gram-stain-positive, spore-forming bacteria indistinguishable by pulsed-field gel electrophoresis were isolated from non-dairy protein shakes in bloated bottles. One of the isolates, strain IEH 97212T, was selected for further study. The strain was closely related to Clostridium sporogenes and Clostridium botulinum Group 1 based on 16S rRNA gene sequence similarities. Phylogenetic analysis also showed that strain IEH 97212T and strain PE (=DSM 18688), a bacterium isolated from solfataric mud, had identical 16S rRNA gene sequences...
July 10, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28691473/oral-probiotics-in-the-management-of-gingivitis-in-diabetic-patients-a-double-blinded-randomized-controlled-study
#12
S Sabatini, D Lauritano, V Candotto, F J Silvestre, G M Nardi
Diabetic patients are more prone to develop infections such as periodontal diseases. Bacteriotherapy with the concept of using good bacterial strains to replace the pathogenic ones emerged as a fascinating field due to the increasing incidence of antibiotic resistance. The aim of this study was to evaluate if a particular combination of probiotics (Lactobacillus Reuteri DSM 17938 and Lactobaciullus Reuteri ATCC PTA 5289) is useful in treating gingivitis in diabetic patients. Eighty adult patients with diagnosis of controlled diabetes type II and gingivitis were enrolled for this study and randomized in two groups...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28686559/-attenuated-psychosis-syndrome-a-new-diagnostic-category-for-further-study-in-dsm-5
#13
G Samiotakis, C Kollias, H Lazaratou, D Anagnostopoulos, V Kontaxakis
In recent years an increasing number of studies focus on the issue of early diagnosis and intervention. At the same time, a large number of special service units for early psychosis have been established around the world especially in Australia, USA, UK, Germany etc. Recently, similar units operate in Greece also. The Diagnostic Manual of Mental Disorders of the American Psychiatric Association in its latest edition in 2013 (DSM-5), introduced the category "Attenuated Psychosis Syndrome" (APS) for people with early psychotic experiences in the section: "Conditions for further study '...
April 2017: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/28674504/antigliadin-antibodies-aga-igg-are-related-to-neurochemistry-in-schizophrenia
#14
Laura M Rowland, Haley K Demyanovich, S Andrea Wijtenburg, William W Eaton, Katrina Rodriguez, Frank Gaston, Daniela Cihakova, Monica V Talor, Fang Liu, Robert R McMahon, L Elliot Hong, Deanna L Kelly
Inflammation may play a role in schizophrenia; however, subgroups with immune regulation dysfunction may serve as distinct illness phenotypes with potential different treatment and prevention strategies. Emerging data show that about 30% of people with schizophrenia have elevated antigliadin antibodies of the IgG type, representing a possible subgroup of schizophrenia patients with immune involvement. Also, recent data have shown a high correlation of IgG-mediated antibodies between the periphery and cerebral spinal fluid in schizophrenia but not healthy controls, particularly AGA IgG suggesting that these antibodies may be crossing the blood-brain barrier with resulting neuroinflammation...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28673755/psychomotor-assessment-as-a-tool-to-differentiate-schizophrenia-from-other-psychotic-disorders
#15
S Janssens, H Moens, V Coppens, F Vandendriessche, W Hulstijn, B Sabbe, M Morrens
GOAL: The aim of this study is to assess to what extent psychomotor assessment can aid the clinician in differentiating between schizophrenia and other psychotic disorders. METHODS: Enrolled subjects were recent in remission patients (n=304), who all met DSM-IV (APA, 2013) criteria for either schizophrenia (Sz; n=117), schizoaffective disorder (SaD; n=36), psychotic disorder not otherwise specified (P-NOS) (n=86), substance/medication-induced psychotic disorder (SIPD; n=33) or major depressive disorder with psychotic features (MDD-p; n=32)...
June 30, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28665526/cognitive-emotion-regulation-strategies-associated-with-the-dsm-5-posttraumatic-stress-disorder-criteria
#16
Antonia N Kaczkurkin, Yinyin Zang, Natalie G Gay, Alan L Peterson, Jeffrey S Yarvis, Elisa V Borah, Katherine A Dondanville, Elizabeth A Hembree, Brett T Litz, Jim Mintz, Stacey Young-McCaughan, Edna B Foa
Maladaptive cognitive emotion regulation strategies have been proposed to contribute to the maintenance of posttraumatic stress disorder (PTSD). Prior work has focused on the relationship between these strategies and PTSD as a whole, rather than on how they are related to each PTSD symptom cluster. The purpose of the current study was to determine whether cognitive emotion regulation strategies are predictive of certain PTSD symptom clusters under the Diagnostic and Statistical Manual of Mental Disorders 5th ed...
June 30, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28662104/vibrio-aphrogenes-sp-nov-in-the-rumoiensis-clade-isolated-from-a-seaweed
#17
Mami Tanaka, Shoko Endo, Fumihito Kotake, Nurhidayu Al-Saari, A K M Rohul Amin, Gao Feng, Sayaka Mino, Hidetaka Doi, Yoshitoshi Ogura, Tetsuya Hayashi, Wataru Suda, Masahira Hattori, Isao Yumoto, Toko Sawabe, Tomoo Sawabe, Toshiyoshi Araki
A novel strain Vibrio aphrogenes sp. nov. strain CA-1004T isolated from the surface of seaweed collected on the coast of Mie Prefecture in 1994 [1] was characterized using polyphasic taxonomy including multilocus sequence analysis (MLSA) and a genome based comparison. Both phylogenetic analyses on the basis of 16S rRNA gene sequences and MLSA based on eight protein-coding genes (gapA, gyrB, ftsZ, mreB, pyrH, recA, rpoA, and topA) showed the strain could be placed in the Rumoiensis clade in the genus Vibrio...
2017: PloS One
https://www.readbyqxmd.com/read/28655025/effect-of-buprenorphine-weekly-depot-cam2038-and-hydromorphone-blockade-in-individuals-with-opioid-use-disorder-a-randomized-clinical-trial
#18
Sharon L Walsh, Sandra D Comer, Michelle R Lofwall, Bradley Vince, Naama Levy-Cooperman, Debra Kelsh, Marion A Coe, Jermaine D Jones, Paul A Nuzzo, Fredrik Tiberg, Behshad Sheldon, Sonnie Kim
Importance: Buprenorphine is an efficacious, widely used treatment for opioid use disorder (OUD). Daily oral transmucosal formulations can be associated with misuse, diversion, and nonadherence; these limitations may be obviated by a sustained release formulation. Objective: To evaluate the ability of a novel, weekly, subcutaneous buprenorphine depot formulation, CAM2038, to block euphorigenic opioid effects and suppress opioid withdrawal in non-treatment-seeking individuals with OUD...
June 22, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28652919/-khelaifiella-massiliensis-niameybacter-massiliensis-brachybacterium-massiliense-enterobacter-timonensis-massilibacillus-massiliensis-new-bacterial-species-and-genera-isolated-from-the-gut-microbiota-of-healthy-infants
#19
M Tidjani Alou, F Cadoret, S Brah, A Diallo, C Sokhna, V Mehrej, J-C Lagier, P-E Fournier, D Raoult
The main characteristics of 'Khelaifiella massiliensis' strain Mt13(T) (= CSUR P1935, = DSM100591), 'Niameybacter massiliensis' strain Mt14(T) (= CSUR P1909, = DSM100592), 'Brachybacterium massiliense' strain MT5(T) (= CSUR P2240, = DSM101766), 'Enterobacter timonensis' strain mt20(T) (= CSUR P2201, = DSM 101775) and 'Massilibacillus massiliensis' strain Marseille-P2411(T) (= CSUR P2411, = DSM102838), new species isolated from the gut of healthy African infants, are presented.
September 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/28652499/a-cross-sectional-cohort-study-of-prevalence-co-morbidities-and-correlates-of-attention-deficit-hyperactivity-disorder-among-adult-patients-admitted-to-the-li-ka-shing-psychiatric-outpatient-clinic-hong-kong
#20
V Mc Leung, L F Chan
OBJECTIVE: To examine the prevalence, co-morbidities, and correlates of attention-deficit hyperactivity disorder (ADHD) among adult patients who attended the Li Ka Shing psychiatric outpatient clinic (LKSPC), Hong Kong. METHODS: This study was a cross-sectional cohort study of patients consecutively referred to LKSPC over a 3-month period for evaluation of adult ADHD in 2 phases. In the screening phase, the Adult ADHD Self-Report Scale-v1.1 (ASRS-v1.1) Screener and Symptom Checklist and Sheehan Disability Scale (SDS) were used in the evaluation...
June 2017: East Asian Archives of Psychiatry: Official Journal of the Hong Kong College of Psychiatrists
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