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Acne vulgaris

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https://www.readbyqxmd.com/read/29782471/new-approach-in-acne-therapy-a-specific-bacteriocin-activity-and-a-targeted-anti-il-8-property-in-just-1-probiotic-strain-the-l-salivarius-ls03
#1
Francesca Deidda, Angela Amoruso, Stefania Nicola, Teresa Graziano, Marco Pane, Luca Mogna
GOALS: The aim of this research was to assess the antibacterial activity of Lactobacillus salivarius LS03 (DSM 22776) against Propionibacterium acnes and its anti-inflammatory properties by inhibiting P. acnes-induced interleukin-8 (IL-8) release. BACKGROUND: Acne is the most common skin disease, causing significant psychosocial problems for those afflicted. Currently available agents for acne treatment, such as oral antibiotics, have limited use. Thus, development of novel agents to treat this disease is needed...
May 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29781900/concomitant-use-of-1-550-nm-nonablative-fractional-laser-with-low-dose-isotretinoin-for-the-treatment-of-acne-vulgaris-in-asian-patients-a-randomized-split-face-controlled-study
#2
Jun Xia, Guanglei Hu, Die Hu, Songmei Geng, Weihui Zeng
BACKGROUND: Nonablative fractional laser (NAFL) has been shown to improve the appearance of inflammatory acne and acne scars. Isotretinoin is effective for the treatment of moderate-to-severe cases of recalcitrant acne. However, the recommended dose of isotretinoin can have profound effects. OBJECTIVE: To investigate the clinical efficacy and safety of performing NAFL treatment in patients with moderate-to-severe acne vulgaris under treatment with low-dose oral isotretinoin...
May 16, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29771216/mindfulness-based-cognitive-hypnotherapy-and-skin-disorders
#3
Philip D Shenefelt
Mindfulness-based cognitive hypnotherapy integrates mindfulness, cognitive-behavioral therapy, and hypnotherapy to improve physical, emotional, mental, and/or spiritual aspects of skin disorders. Meditation, including mindfulness meditation, and hypnosis both utilize trance phenomena to help produce focalization and specific improvements in skin disorders through psycho-neuro-endocrine-immunologic mechanisms. Hypnosis, cognitive hypnotherapy, focused meditation, and mindfulness meditation are discussed with respect to improving various skin disorders including acne, acne excoriée, alopecia areata, atopic dermatitis, congenital ichthyosiform erythroderma, dyshidrotic dermatitis, erythema nodosum, erythromelalgia, furuncles, glossodynia, herpes simplex, hyperhidrosis, ichthyosis vulgaris, lichen planus, neurodermatitis, nummular dermatitis, postherpetic neuralgia, prurigo nodularis, pruritus, psoriasis, rosacea, trichotillomania, urticaria, verruca vulgaris, and vitiligo...
July 2018: American Journal of Clinical Hypnosis
https://www.readbyqxmd.com/read/29768083/sebo-pharmacokinetics-a-proposed-percutaneous-sebum-egression-method
#4
Rasika Reddy, John Havens Cary, Akram Elmahdy, Howard Maibach
BACKGROUND/AIMS: The sebaceous gland is widely believed a critical factor in the pathogenesis of acne vulgaris. Although extensive studies document the ability of oral and topical treatments to improve acne, little is known about the quantification and mechanism of drug delivery via the sebaceous gland. A percutaneous egression method presents a way to study how drugs reaching the bloodstream can enter the skin. METHODS: A literature search was performed across databases (PubMed, Embase, and Google Scholar) and the University of California, San Francisco (UCSF) textbook library with relevant search terms...
May 16, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29760618/-demodex-spp-as-a-possible-aetiopathogenic-factor-of-acne-and-relation-with-acne-severity-and-type
#5
Ulviye Güvendi Akçınar, Emine Ünal, Funda Doğruman Al
Introduction: Acne is a very common skin disease in adolescents and young adults, but it also affects adults. However, its aetiology is not yet fully understood. Demodex appears to be associated with multiple skin disorders, but controversy persists. Some reports indicate a connection between acne vulgaris and demodicosis. Aim: To confirm the association between Demodex infestation and acne vulgaris. Material and methods: A total of 108 patients were enrolled in the acne group...
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29756631/patients-with-acne-vulgaris-have-a-distinct-gut-microbiota-in-comparison-with-healthy-controls
#6
Yongqiong Deng, Hong Wang, Jiyuan Zhou, Yunzhou Mou, Guiqiang Wang, Xia Xiong
Acne vulgaris has been postulated to have a gastrointestinal mechanism; however, little is known about gut microbiota dysfunction in this condition. The aim of this cross-sectional study was to investigate whether the gut microbiota is altered in acne. Faecal bacterial diversity was analysed in 43 patients with acne and 43 controls, using hypervariable tag sequencing of the V3-V4 region of the 16S rDNA gene. Distinct differences were found in microbial diversity between patients with acne and controls (Shannon diversity index (p = 0...
May 14, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29729198/acne-at-the-regional-dermatology-training-centre-rdtc-tanzania-clinical-social-and-demografic-characteristics-of-patients-with-focus-on-severity-factors
#7
U A Amani, J Mshana, S Kiprono, D Mavura, E J Masenga, S Cazzaniga, G Todd, H Beltraminelli
Acne is a common dermatosis and is associated with a significant disease burden. Despite this, studies from Sub-Saharan Africa are rare. However, the prevalence of acne vulgaris in developing countries is increasing, eventually due to the adoption of a western life style especially in urban areas. We conducted an analytical, cross-sectional, hospital-based study between September 2012 and February 2013 (6 months) at the Regional Dermatology Training Centre (RDTC) in Moshi, Tanzania. The clinical, social, and demographic characteristics of patients with acne were assessed...
May 5, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29725277/use-of-oral-contraceptives-for-management-of-acne-vulgaris-and-hirsutism-in-women-of-reproductive-and-late-reproductive-age
#8
Radosław Słopień, Ewa Milewska, Piotr Rynio, Błażej Męczekalski
Hormonal contraception in both reproductive and late reproductive age, as well as contraceptive action, is used also for other indications like dysmenorrhoea, menstrual disorders, endometriosis, acne vulgaris, and hirsutism. Acne vulgaris and hirsutism are important signs related to hyperandrogenaemia and present a serious medical problem for the patients and a challenge for medical doctors in terms of effective treatment. The application of hormonal contraception to treat acne vulgaris and hirsutism requires knowledge of the mechanism of antiandrogenic actions and the possible contraindications and complications...
March 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29722425/comparative-study-of-the-bactericidal-effects-of-indocyanine-green-and-methyl-aminolevulinate-based-photodynamic-therapy-on-propionibacterium-acnes-as-a-new-treatment-for-acne
#9
Seung-Hwan Choi, Jeong-Wan Seo, Ki-Ho Kim
Acne vulgaris is one of the most common dermatological problems, and its therapeutic options include topical and systemic retinoids and antibiotics. However, increase in problems associated with acne treatment, such as side-effects from conventional agents and bacterial resistance to antibiotics, has led to greater use of photodynamic therapy. The purpose of this study was to compare the bactericidal effects of indocyanine green- and methyl aminolevulinate-based photodynamic therapy on Propionibacterium acnes...
May 3, 2018: Journal of Dermatology
https://www.readbyqxmd.com/read/29721027/acupuncture-for-acne-vulgaris-a-systematic-review-and-meta-analysis
#10
REVIEW
Suzi S Y Mansu, Haiying Liang, Shefton Parker, Meaghan E Coyle, Kaiyi Wang, Anthony L Zhang, Xinfeng Guo, Chuanjian Lu, Charlie C L Xue
Purpose: To conduct a systematic review and meta-analysis to determine the current best available evidence of the efficacy and safety of acupuncture and related therapies for acne vulgaris. Methods: Eleven English and Chinese databases were searched to identify randomized controlled trials (RCTs) of acne vulgaris compared to pharmacotherapies, no treatment, and sham or placebo acupuncture. Methodological quality was assessed using Cochrane Collaboration's risk of bias tool...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29705755/chemical-peels-for-acne-vulgaris-a-systematic-review-of-randomised-controlled-trials
#11
Xiaomei Chen, Sheng Wang, Ming Yang, Li Li
OBJECTIVE: We evaluated current evidence from randomised controlled trials (RCTs) regarding the effectiveness of chemical peeling for treating acne vulgaris. METHODS: Standard Cochrane methodological procedures were used. We searched MEDLINE, Cochrane Central Register of Controlled Trials and EMBASE via OvidSP through April 2017. Reviewers independently assessed eligibility, risk of bias and extracted data. RESULTS: Twelve RCTs (387 participants) were included...
April 28, 2018: BMJ Open
https://www.readbyqxmd.com/read/29692454/evaluation-of-adolescents-diagnosed-with-acne-vulgaris-for-quality-of-life-and-psychosocial-challenges
#12
Murat Eyüboglu, Incilay Kalay, Damla Eyüboglu
Background: Acne vulgaris is a common skin condition which affects most adolescents. It has a major impact on quality of life and psychosocial well-being. Aims: The aims of the study were to examine the psychosocial effects of acne on adolescents and changes in quality of life, and to reveal any difference in the possible effect between genders. In addition, an investigation of the association between acne severity and quality of life as well as psychosocial stress was conducted...
March 2018: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/29675912/tumor-necrosis-factor-%C3%AE-308-g-a-and-interleukin-1-%C3%AE-511-c-t-gene-polymorphisms-in-patients-with-scarring-acne
#13
Gulsen Akoglu, Cagman Tan, Deniz Cagdas Ayvaz, Ilhan Tezcan
BACKGROUND: Acne is a chronic inflammatory skin disorder which may heal with scarring. Tumor necrosis factor alpha (TNF α) and interleukin 1 β (IL-1β) are considered as the main responsible proinflammatory mediators of acne pathogenesis. Oversecretion of these cytokines was found to be associated with TNF α-308 G>A and IL-1β-511 C<T polymorphisms. AIM: To evaluate the association of TNF α-308 and IL-1β-511 gene polymorphisms with acne and postacne scarring susceptibility and acne severity...
April 19, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29663460/treatment-of-atrophic-acne-scarring-with-fractional-micro-plasma-radio-frequency-in-chinese-patients-a-prospective-study
#14
Ting Lan, Yan Xiao, Li Tang, Michael R Hamblin, Rui Yin
BACKGROUND: Acne scarring is a common disfiguring sequela of acne vulgaris which can lead to serious psychosocial problems and have a negative effect on patients' quality of life. Although a variety of approaches can be used to treat atrophic acne scars, disadvantages such as long-healing time, dyspigmentation, infections, and prolonged erythema make these treatments unsatisfactory especially for Asians. Fractional micro-plasma radio-frequency is a novel technology that produces minor ablation to the epidermis to promote rapid re-epithelialization, while the radio-frequency evoked thermal effect can stimulate regeneration and remodeling of dermal fibroblasts...
April 16, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29662684/a-comparison-of-combined-oral-contraceptives-containing-chlormadinone-acetate-versus-drospirenone-for-the-treatment-of-acne-and-dysmenorrhea-a-randomized-trial
#15
Unnop Jaisamrarn, Somsook Santibenchakul
Background: Oral contraceptives (OCs), aside from contraceptive efficacy, have been widely known for their non-contraceptive benefits. Different progestogens component of the OCs have been shown to improve the skin, hair, menstrual cycle related disorders and dysmenorrhoeic pain. Thus, we compared the efficacy of OCs containing ethinyl estradiol (EE) and chlormadinone acetate (CMA) versus OCs containing EE and drospirenone (DRSP) for the treatment of acne and dysmenorrhea. Methods: This study was an investigator-blinded, randomized, parallel group study conducted at the Family Planning Clinic, Department of Obstetrics and Gynaecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand...
2018: Contraception and Reproductive Medicine
https://www.readbyqxmd.com/read/29657672/efficacy-and-safety-evaluation-of-high-density-intense-pulsed-light-in-the-treatment-of-grades-ii-and-iv-acne-vulgaris-as-monotherapy-in-dark-skinned-women-of-child-bearing-age
#16
Ajay J Deshpande
Background: Acne vulgaris is a self-limiting, chronic inflammatory disorder of the pilosebaceous unit characterized by exacerbations and remissions. It is often the early manifestation of puberty, and in girls it appears relatively early. In women, acne tends to become aggravated during the menstrual period, pregnancy, and in those who are on progesterone. Acne treatment is divided into two parts: topical and systemic. For Grades 1 and 2 acne, topical treatment is sufficient, while for Grades 3 and 4 acne, systemic drugs such as tetracyclines and retinoids are required to control the symptoms...
April 2018: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29645385/s1-leitlinie-dermatosen-bei-dermaler-lymphostase
#17
Joachim Dissemond, Finja Jockenhöfer, Anya Miller, Günter Kurzhals, Shahrouz Noori, Stefanie Reich-Schupke, Martin Schlaeger, Erich Schubert, Markus Stücker, Tobias Weberschock, Hans Wilfried Jungkunz
Das Ziel dieser S1-Leitlinie ist es, aktuelles Wissen über dermatologisch relevante Krankheitsbilder bei lokal begrenzter dermaler Lymphostase an allen Lokalisationen des Hautorgans zu vermitteln, um diese frühzeitig zu erkennen, diagnostisch zu sichern und gezielt zu behandeln. Wann immer möglich, sollte diese Therapie anhand klar definierter Algorithmen stadiengerecht erfolgen. Die im klinischen Alltag häufig auftauchenden differenzialdiagnostischen und therapeutischen Fragen lassen eine aktuelle Leitlinie notwendig erscheinen...
April 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29643449/an-automatic-diagnosis-method-of-facial-acne-vulgaris-based-on-convolutional-neural-network
#18
Xiaolei Shen, Jiachi Zhang, Chenjun Yan, Hong Zhou
In this paper, we present a new automatic diagnosis method for facial acne vulgaris which is based on convolutional neural networks (CNNs). To overcome the shortcomings of previous methods which were the inability to classify enough types of acne vulgaris. The core of our method is to extract features of images based on CNNs and achieve classification by classifier. A binary-classifier of skin-and-non-skin is used to detect skin area and a seven-classifier is used to achieve the classification task of facial acne vulgaris and healthy skin...
April 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29611225/optimizing-the-use-of-topical-retinoids-in-asian-acne-patients
#19
REVIEW
Jo-Ann See, Chee Leok Goh, Nobukazu Hayashi, Dae Hun Suh, Flordeliz Abad Casintahan
Acne vulgaris is a common disease among people in Asia. International guidelines and treatment recommendations emphasize the central role of topical retinoids in the management of acne. However, topical retinoids remain underutilized in clinical practise, which may be in part due to fear of retinoid-associated dermatitis/lack of experience, particularly in Asian patients. There is a perception that Asian skin has a greater tendency toward sensitivity compared with Caucasian skin. In our clinical experience, topical retinoid therapy can be used with excellent effect to treat Asians with acne...
April 3, 2018: Journal of Dermatology
https://www.readbyqxmd.com/read/29602922/indicators-of-phagocytosis-in-women-with-acne-during-comprehensive-treatment-that-included-immunotherapy-and-probiotics
#20
Orysya О Syzon, Marianna О Dashko
OBJECTIVE: Introduction: Acne is one of the most common dermatological diseases. It may have a chronic course, leaving permanent marks, and in last years has been tending to have more and more severe clinical course with widespread skin lesions. According to recent studies, the development of acne is due to the combined effect of endogenous and exogenous factors, among which endocrine diseases (quite a significant aspect), disorders of metabolic processes, reduced systemic immunity and phagocytic ability of mononuclear phagocytes and granulocytes at various stages of phagocytosis of pyogenic cocci, which contributes to more severe clinical course, and frequent relapse of this diseases...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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