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https://www.readbyqxmd.com/read/29777495/ameliorative-effect-of-ginseng-extract-on-phthalate-and-bisphenol-a-reprotoxicity-during-pregnancy-in-rats
#1
Islam M Saadeldin, Mohamed A Hussein, Aida Hamid Suleiman, Mahmoud G Abohassan, Mona M Ahmed, Amr A Moustafa, Abdullah F Moumen, Ayman Abdel-Aziz Swelum
Phthalates (such as DEHP) and bisphenol A (BPA) are widely used chemicals in plastics manufacturing and exert public health concerns as endocrine disrupters. This study was designed to investigate the deleterious effect of DEHP and BPA on endocrine profile of pregnant female rats and the combined treatment with ginseng extract (Panax ginseng). Seventy-two pregnant rats were divided into six groups (control, ginseng, DEHP, BPA, Gin + DEHP, and Gin + BPA), 12 females per each group. The drugs were supplemented from pregnancy day 0 until day 20...
May 18, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29775631/effect-of-central-injection-of-tumor-necrosis-factor-like-cytokine-1a-and-interferons-on-food-intake-in-chicks
#2
Tetsuya Tachibana, Yoko Ishimaru, Ryosuke Makino, Sakirul Islam Khan, Mark A Cline
In mammals, anorexia accompanying infection is thought to be mediated via cytokines including interleukins, interferons (IFNs), and tumor necrosis factor (TNF). However, there is a lack of related knowledge on birds. Therefore, the purpose of the present study was to determine if cytokines are associated with reduced food intake in chicks (Gallus gallus). Specifically, we evaluated the effects of TNF-like cytokine 1A (TL1A), a member of the TNF family, interferon-α (IFN-α), and interferon-γ (IFN-γ) on food intake...
May 15, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29775471/host-directed-combinatorial-rnai-improves-inhibition-of-diverse-strains-of-influenza-a-virus-in-human-respiratory-epithelial-cells
#3
Michael A Estrin, Islam T M Hussein, Wendy B Puryear, Anne C Kuan, Stephen C Artim, Jonathan A Runstadler
Influenza A virus infections are important causes of morbidity and mortality worldwide, and currently available prevention and treatment methods are suboptimal. In recent years, genome-wide investigations have revealed numerous host factors that are required for influenza to successfully complete its life cycle. However, only a select, small number of influenza strains were evaluated using this platform, and there was considerable variation in the genes identified across different investigations. In an effort to develop a universally efficacious therapeutic strategy with limited potential for the emergence of resistance, this study was performed to investigate the effect of combinatorial RNA interference (RNAi) on inhibiting the replication of diverse influenza A virus subtypes and strains...
2018: PloS One
https://www.readbyqxmd.com/read/29775220/cystatin-c-is-a-more-reliable-biomarker-for-determining-egfr-to-support-drug-development-studies
#4
REVIEW
Sumit Kar, Sabina Paglialunga, Rafiqul Islam
Glomerular filtration rate (GFR) is routinely used as a surrogate endpoint for the development of investigational drugs in clinical trials. GFR and staging of chronic kidney disease are typically assessed by measuring the concentration of endogenous serum biomarkers such as albumin and creatinine. However, creatinine is subject to high biological variability, and levels of creatinine do not rise until nearly 50% of kidney function is damaged, leading to inaccurate chronic kidney disease staging and false negatives...
May 18, 2018: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29775143/testing-the-effectiveness-and-the-contribution-of-experimental-supercharge-reversed-end-to-side-nerve-transfer
#5
Mustafa Nadi, Sudheesh Ramachandran, Abir Islam, Joanne Forden, Gui Fang Guo, Rajiv Midha
OBJECTIVE Supercharge end-to-side (SETS) transfer, also referred to as reverse end-to-side transfer, distal to severe nerve compression neuropathy or in-continuity nerve injury is gaining clinical popularity despite questions about its effectiveness. Here, the authors examined SETS distal to experimental neuroma in-continuity (NIC) injuries for efficacy in enhancing neuronal regeneration and functional outcome, and, for the first time, they definitively evaluated the degree of contribution of the native and donor motor neuron pools...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29774431/complete-genome-sequences-of-three-novel-cycloviruses-identified-in-a-dragonfly-odonata-anisoptera-from-china
#6
Saif Ul Islam, Wenzhong Lin, Ran Wu, Chen Lin, Waqar Islam, Muhammad Arif, Zhenguo Du, Zujian Wu
Three cycloviruses (genus Cyclovirus, family Circoviridae) were recovered from a dragonfly (Odonata: Anisoptera) captured in Fuzhou, China. The three cycloviruses, named dragonfly associated cyclovirus 9, 10 and 11 (DfCyV-9, -10, -11), respectively, show 56.1-79.6% genome-wide identity to known cycloviruses and 61.6-65.1% among themselves. Thus, according to the current species demarcation criteria, they represent three novel cycloviruses. Notably, DfCyV-10 has a predicted replication-associated protein (Rep) that is most similar to that of bat associated cyclovirus 2 (BatACyV-2), a cyclovirus discovered in China, with 79...
May 17, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29774349/role-of-arsenic-3-oxidation-state-methyltransferase-in-arsenic-mediated-apl-treatment-an-in-vitro-investigation
#7
Yasen Maimaitiyiming, Chao Wang, Shi Xu, Khairul Islam, Ye Jia Chen, Chang Yang, Qian Qian Wang, Hua Naranmandura
Arsenic (+3 oxidation state) methyltransferase (AS3MT) is a key enzyme responsible for arsenic metabolism in humans, which facilitates conversion of arsenic trioxide (As2O3) to more reactive metabolites such as monomethylarsonous acid (MMAIII) and dimethylarsinous acid (DMAIII). However, it is unclear whether the biotransformation of arsenic by AS3MT contributes to the promotion of acute promyelocytic leukemia (APL) therapy. In order to understand the probable role of AS3MT in APL patients, we evaluated the effects of arsenite (iAsIII) and three mixed arsenicals (i...
May 18, 2018: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/29770776/in-situ-transmission-electron-microscopy-of-transistor-operation-and-failure
#8
Baoming Wang, M Zahabul Islam, M Aman Haque, Kelson Chabak, Michael Snure, Eric Heller, Nicholas Robert Glavin
Microscopy is typically used as a post-mortem analytical tool in performance and reliability studies on nanoscale materials and devices. In this study, we demonstrate real-time microscopy of operation and failure of AlGaN/GaN high electron mobility transistors inside the transmission electron microscope (TEM). Loading till failure was performed on the electron transparent transistors to visualize the failure mechanisms caused by self heating. At lower drain voltages, thermo-mechanical stresses induce irreversible microstructural deformation, mostly along the AlGaN/GaN interface, to initiate the damage process...
May 17, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29770334/optimum-antithrombotic-therapy-in-patients-requiring-long-term-anticoagulation-and-undergoing-percutaneous-coronary-intervention
#9
REVIEW
Nayan Agarwal, Dhruv Mahtta, Cecil A Rambarat, Islam Elgendy, Ahmed N Mahmoud
Management of patients on long-term anticoagulation requiring percutaneous coronary intervention is challenging. Triple therapy with oral anticoagulant and dual antiplatelet therapy is the standard of care. However, there is no strong evidence to support this strategy. There is emerging data regarding the safety and efficacy of dual therapy with oral anticoagulant and single antiplatelet therapy in these patients. In this comprehensive review we highlight available evidence regarding various antithrombotic regimens' efficacy and safety in patient with coronary artery disease undergoing percutaneous coronary intervention with long-term anticoagulation therapy requirements...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29770218/elevated-serum-levels-of-malondialdehyde-and-cortisol-are-associated-with-major-depressive-disorder-a-case-control-study
#10
Md Rabiul Islam, Md Reazul Islam, Imtiaz Ahmed, Abdullah Al Moktadir, Zabun Nahar, Mohammad Safiqul Islam, Shelina Fatema Binte Shahid, Sheikh Nazrul Islam, Md Saiful Islam, Abul Hasnat
Objectives: Major depressive disorder is diagnosed on the basis of patient's self-reported experiences, behavior reported by relatives, and a mental status examination, and yet we do not have any reliable biomarker for this. Mood-regulating pathways are affected by oxidative injury to lipids and cortisol is released into the blood due to stimulation of corticotrophin receptors in the adrenal cortex. Here, we aimed to determine serum levels of malondialdehyde and cortisol in major depressive disorder patients and controls...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29769638/superconducting-and-normal-state-anisotropy-of-the-doped-topological-insulator-sr-0-1-bi-2-se-3
#11
M P Smylie, K Willa, H Claus, A E Koshelev, K W Song, W-K Kwok, Z Islam, G D Gu, J A Schneeloch, R D Zhong, U Welp
Srx Bi2 Se3 and the related compounds Cux Bi2 Se3 and Nbx Bi2 Se3 have attracted considerable interest, as these materials may be realizations of unconventional topological superconductors. Superconductivity with Tc  ~3 K in Srx Bi2 Se3 arises upon intercalation of Sr into the layered topological insulator Bi2 Se3 . Here we elucidate the anisotropy of the normal and superconducting state of Sr0.1 Bi2 Se3 with angular dependent magnetotransport and thermodynamic measurements. High resolution x-ray diffraction studies underline the high crystalline quality of the samples...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29769511/an-elderly-lady-with-neurobrucellosis-and-multiple-co-morbid-conditions
#12
M N Islam
Neurobrucellosis is a rare (1.7-7.0% of prevalence) neurological complication of brucellosis which has neither a typical clinical picture nor specific cerebrospinal fluid (CSF) findings and mimics other neurological disorders leading to clinical diagnostic dilemmas. This study describes one elderly patient of neurobrucellosis with fever, irrelevant behavior, sweating, fatigue, drowsiness, neck stiffness inability to speak and reduced activity for about 10 days hailing from Beanibazar, Sylhet, Bangladesh admitted in Mount Adora Hospital, Sylhet, Bangladesh on 16th October 2016...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769492/relationship-between-triglyceride-and-hdl-c-ratio-with-acute-coronary-syndrome
#13
M Z Islam, M N Islam, T K Bhowmik, B Saha, M S Hossain, H Ahmed, M S Ali, S S Shakil, P K Paul
Cardiovascular diseases (CVD) is the leading cause of death worldwide, responsible for one third of death, coronary artery disease (CAD) is the most common cause. Dyslipidaemiais one of the major contributors increased of CAD risk. This study was aimed to find out the relationship between triglyceride and HDL cholesterol ratio with acute coronary syndrome. This cross sectional study was conducted in the department of Cardiology, Mymensingh Medical College Hospital from August 2009 to May 2010. Smoking, hypertension, serum total cholesterol level, serum HDL-C, LDL-C, triglyceride (TG) level were important variable considered...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769491/management-of-traumatic-unstable-thoracolumbar-spine-conservative-versus-operative-treatment
#14
M M Rahman, N A Islam, M S Islam, M M Rahman, M A Islam, M K Alamgir, M H Sarker
Traumatic thoracolumbar spine injury result in significant instability of the spine and leads to an acute on delayed neurological deficit. Objective of the study is to find a better option in the management of unstable traumatic thoracolumbar spine with incomplete neurological lesion. This was quasi-experimental study. The study was carried out at National Institute of Traumatology & Orthopedic Rehabilitation (NITOR), Dhaka, Bangladesh from January 2006 to December 2008. A total number of 40 patients with traumatic thoracolumbar spine injuries with incomplete neurological lesion were selected purposively...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769485/changes-of-peak-expiratory-flow-rate-in-adult-asthmatic-patient
#15
S Nasreen, A Nessa, F Islam, A Khanam, R Sultana, R Rahman, M Hossain
Asthma is a common pulmonary disorder characterizerized by airway inflammation, airway- hyper reactivity, and reversible airflow obstruction. The classic triad of symptoms is wheezing, chronic episodic dyspnea and chronic cough. The prevalence of asthma increased steadily over the latter part of the last century, first in the developed and then in the developing world. The number of people with asthma in the world may be as high as 334 million. Asthma in Bangladesh appears to be a substantial public health problem: an estimated 11...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769484/prevalence-of-non-alcoholic-fatty-liver-disease-and-its-biochemical-predictors-in-patients-with-type-2-diabetes-mellitus
#16
M A Kabir, M Z Uddin, N I Siddiqui, I H Robi, M S Malek, M S Islam, S Rahman, M S Hossain, S K Mahapatra, M J Alam, F Ahmad, M S Alam, M A Islam
Non-alcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver condition in the Western world and it is commonly associated with type 2 diabetes mellitus (DM). The aim of this study to determine the prevalence of NAFLD and identify the predisposing factors in type 2 DM patients with NAFLD. Total of 258 patients of type 2 DM were included in this observational study in the Department of Medicine, Mymensingh Medical College Hospital, Mymensingh, Bangladesh from 11th May 2013 to 11th November 2013...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769483/association-between-serum-apolipoprotein-b-and-acute-ischaemic-stroke
#17
M S Islam, M J Uddin, M Bhattacharjee, M N Farzana, R K Talukder, M A Rahman, M Mohsin, M A Rouf, H Pandit, M R Karim, R Ara, S Akhter, G Saha, M Oliullah, M S Ali, R Parveen
Stroke is one of the leading causes of death and disability in developed as well as developing countries like Bangladesh. There is a crucial need to identify additional risk factors that are easily measurable and treatable in general population. Role of serum lipids, lipoproteins and lipoprotein related variables in the prediction of stroke is less clear. Abnormalities in plasma lipoproteins are the most firmly established and best understood risk factors for atherosclerosis and they are probable risk factors for ischaemic stroke, largely by their link to atherosclerosis...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769482/aetiological-factors-of-female-genitourinary-fistula
#18
F Z Aalpona, M Kamrul-Hasan, F Islam, S Hossain, S Akter, K F Ananya
The purpose of this observational cross-sectional study was to evaluate the histories of women with urinary incontinence caused by genitourinary fistulae in Bangladesh. This is an exploratory analysis to investigate possible contributing factors to the development of urogenital fistulae. Sixty four (64) women who were treated for urogenital fistulae at the National Fistula Center, Dhaka Medical College Hospital, Dhaka, Bangladesh were interviewed from July 2013 to December 2013. Their average age was 35.91 years; majorities were illiterate; had early marriage and came from poor family...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29768819/tuning-wall-thicknesses-in-mesoporous-silica-films-for-optimization-of-optical-anti-reflective-properties
#19
Nawfel Abdullah, Md Shahriar A Hossain, Konstantin Konstantinov, Hirofumi Tanabe, Mikiya Matsuura, Kazuhiko Maekawa, Amanullah Fatehmulla, Wazirzada Aslam Farooq, Md Tofazzal Islam, Yoshio Bando, Yusuf Valentino Kaneti, Yusuke Yamauchi
This work reports the fabrication of mesoporous silica films with controllable wall thicknesses by spin coating of precursor solutions consisting of polystyrene-block-polybutadiene-block-polystyrene based triblock copolymers (Hydrogenated methyl Styrene Ethylene Butadiene methyl Styrene, HmSEBmS) and tetraethyl orthosilicate (TEOS) followed by calcination in air at 600 °C, for optical anti-reflection films. By changing the relative weight of the triblock polymer to TEOS, the pore-to-pore distance in the mesoporous silica film can be controlled without significantly affecting the size of the mesopores, thus, enabling effective control of the refractive index and porosity of the films...
January 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29768816/preparation-of-ultraviolet-curing-type-silicone-rubbers-containing-mesoporous-silica-fillers
#20
Nawfel Abdullah, Md Shahriar A Hossain, Amanullah Fatehmulla, Wazirzada Aslam Farooq, Md Tofazzal Islam, Nobuyoshi Miyamoto, Yoshio Bando, Yuichiro Kamachi, Victor Malgras, Yusuke Yamauchi, Norihiro Suzuki
Here we have been focusing on mesoporous silica (MPS) as inorganic filler material to improve the mechanical strength of silicone rubbers. The MPS particles are more effective in reducing the coefficient of thermal expansion (CTE) and hardening silicone rubber composites when compared to commercially available nonporous silica particles. In this study, we utilize ultraviolet curing type silicone rubbers and prepare MPS composites according to a simple single-step method. From an industrial viewpoint, simplifying the fabrication processes is critical...
January 1, 2018: Journal of Nanoscience and Nanotechnology
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