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Hypomagnesia

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https://www.readbyqxmd.com/read/25923028/pseudo-gitelman-syndrome-associated-with-pregnancy
#1
Masato Yoshihara, Akira Sayo, Michinori Mayama, Hidenori Oguchi
BACKGROUND: Gitelman syndrome is a rare inherited renal tubulopathy associated with metabolic alkalosis and electrolyte disorders. Pseudo Gitelman syndrome presents with the same clinical characteristics as Gitelman syndrome, yet without genetic mutations in SLC12A3. CASE: A 32-year-old woman with no remarkable medical and family history developed hypokalemia at 32 weeks of gestation. Laboratory findings were consistent with Gitelman syndrome and potassium supplementation was initiated...
October 2015: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/23569986/science-behind-cisplatin-induced-nephrotoxicity-in-humans-a-clinical-study
#2
RANDOMIZED CONTROLLED TRIAL
P A Arunkumar, G L Viswanatha, N Radheshyam, H Mukund, M S Belliyappa
OBJECTIVE: To investigate the relationship between serum electrolyte changes and cisplatin induced nephrotoxicity. METHODS: We collected data from 18 patients undergoing cisplatin chemotherapy including serum electrolytes, creatinine, blood urea nitrogen (BUN) and urine potassium, sodium and pH levels before and after the cisplatin chemotherapy. All the patients had cancer and were treated with 40-50 mg/day cisplatin. Renal injury was assessed by measuring serum electrolytes, creatinine, BUN levels and urine potassium, sodium and pH levels...
August 2012: Asian Pacific Journal of Tropical Biomedicine
https://www.readbyqxmd.com/read/23153453/toxicities-complications-and-clinical-encounters-during-intraperitoneal-chemotherapy-in-17-women-with-ovarian-cancer
#3
Virginia Sun, Shirley Otis-Green, Robert Morgan, Mark Wakabayashi, Amy Hakim, Maria Elenita Callado, Eunice Yang, Betty Ferrell, Marcia Grant
PURPOSE OF THE RESEARCH: Intraperitoneal (IP) chemotherapy is a viable and superior treatment to standard intravenous (IV) chemotherapy in women with small volume residual ovarian cancer following optimal debulking. Despite this clinical advantage, widespread adoption of the treatment regimen has been hampered by concerns related to toxicities and complications. The purpose of this descriptive study was to describe nursing implications related to toxicities, complications and clinical encounters in 17 women with ovarian cancer who received IP chemotherapy...
June 2013: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/22338923/experience-of-application-blood-screening-and-bone-turnover-markers-for-prevention-of-unwanted-effects-and-early-outcomes-of-teriparatide
#4
Narong Bunyaratavej
This clinical study aimed to provide awareness of the teriparatide injection and also prevention of unwanted events. The 72 cases aged between 52-69 with the inclusion criteria: back pain proved by the x-ray with one or more collapsed spines, no underlying diseases and no history of bone tumor, hyperparathyroid, hypercalcemia. The blood screening for renal, liver profiles, uric acid, mineral profile and bone turnover markers (bCTx, PINP) are used as 6-month monitor. The results showed that the common unwanted effects were hypercalcemia, hyperuricemia, hypomagnesia: 5...
October 2011: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/20567101/-cancer-and-electrolytes-imbalance
#5
Hiroyuki Shibata
The electrolyte imbalance in advanced cancer patients, including hyperkalemia, hypercalcemia and hyponatremia, can be induced by various factors. Hyperkalemia is occasionally induced by chemotherapy for very large malignant tumors, due to tumor lysis syndrome. Hypercalcemia and hyponatremia are often observed in patients with breast cancer, renal cancer, prostate cancer, and the like, as a paraneoplastic syndrome. Some part of hypercalcemia results from osteolysis, but the majority is induced by hormonal factors, such as parathyroid hormone-related protein...
June 2010: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/15535965/dietary-magnesium-depletion-does-not-promote-oxidative-stress-but-targets-apical-cells-within-the-mouse-caput-epididymidis
#6
Patrick Vernet, Aurore Britan, Elyette Gueux, Andrzej Mazur, Joël R Drevet
It is well documented that a dietary deficiency in magnesium can induce oxidative stress and an inflammatory response in animal models. In our study, we have investigated these responses in the mouse epididymis after mice had been fed a magnesium-deficient diet for a 2-week duration. The extracellular and intracellular concentrations of magnesium where shown to be depleted on this diet. This was followed, however, only in the liver of the Mg-deficient animals, by an increase in both alpha 2-macroglobulin (alpha-2m), an acute phase marker, and interleukin-6 transcripts suggesting that an inflammatory response had been initiated...
November 18, 2004: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/14579608/-management-of-serum-magnesium-abnormalities
#7
REVIEW
T Guillaume, J M Krzesinski
Because symptoms associated with hypomagnesia are highly aspecific, this ionic abnormality is rarely searched for although it could be present in as much as 20% of the population. The mode of correction (oral or intravenous) depends on the etiology, severity and clinical consequences of hypomagnesemia. Significant hypermagnesemia only occurs in the presence of renal insufficiency and/or acute excess administration, mainly by the intravenous route. If interruption of administration does not suffice, renal dialysis might become necessary to quickly correct the magnesemium serum levels...
July 2003: Revue Médicale de Liège
https://www.readbyqxmd.com/read/11173316/dofetilide-a-new-class-iii-antiarrhythmic-agent
#8
REVIEW
R Al-Dashti, M Sami
Dofetilide is a new, pure class III antiarrhythmic agent that prolongs the refractory period and action potential duration without having beta-blocking or calcium channel-blocking properties, making it unique among established class III agents. Dofetilide is effective in converting atrial and ventricular arrhythmias, and in maintaining sinus rhythm after cardioversion. Interestingly, it is more effective in converting atrial flutter than atrial fibrillation. It appears to be safe in patients with left ventricular dysfunction and postmyocardial infarction...
January 2001: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/10449829/hypomagnesemia-in-trauma-patients
#9
H Frankel, R Haskell, S Y Lee, D Miller, M Rotondo, C W Schwab
The objective of this study was to determine the incidence of hypomagnesemia in injured patients (versus a general hospital cohort) and to compare total and ionized values with each other and with the incidence of injury severity and ethanol level. It was a descriptive study of consecutive injured patients at a level II trauma center. For 3 months subjects underwent admission paired analysis of blood total magnesium (TMg) and ionized magnesium (IMg). IMg was determined by microanalysis of whole blood (Nova Biomedical, NovaSP9)...
September 1999: World Journal of Surgery
https://www.readbyqxmd.com/read/9154328/effects-of-hypomagnesia-on-histamine-h1-receptor-mediated-facilitation-of-nmda-responses
#10
G W Payne, R S Neuman
1. The ability of histamine to facilitate the N-methyl-D-aspartate (NMDA) induced depolarization of cortical projection neurones was examined by use of grease-gap recording. 2. Histamine (1 to 15 microM) reversibly facilitated the NMDA-induced depolarization yielding a bellshaped concentration-response relationship. The peak enhancement was 167% above the control at 10 microM histamine. Desensitization was present in 4 out of 5 slices on second exposure 40 min following the first exposure. 3. Histamine did not alter the depolarization induced by 10 microM kainate...
May 1997: British Journal of Pharmacology
https://www.readbyqxmd.com/read/7798025/corpuscles-of-stannius-and-blood-flow-regulation-in-freshwater-north-american-eels-anguilla-rostrata-lesueur
#11
D G Butler, G Y Oudit
Cardiac output (CO), heart rate (HR), stroke volume (SV), dorsal aortic blood flow (DABF), dorsal aortic blood pressure (PDA) and plasma electrolytes were monitored in stanniectomized and sham-operated freshwater eels over a 3-week period; branchial shunting and systemic resistance (RSYS) were estimated. DABF was significantly reduced by 45% from 11.72 +/- 0.48 (control) to 6.55 +/- 0.41 (n = 6; day 21) ml.min-1.kg-1 within 3 weeks after the removal of the corpuscles of Stannius. This large reduction in blood flow was due to a 25% decrease in CO and a 100% increase in estimated branchial shunting which preceded the fall in CO...
April 1995: Journal of Endocrinology
https://www.readbyqxmd.com/read/3375116/hypomagnesia-in-the-head-and-neck-cancer-patient
#12
S Harlan
No abstract text is available yet for this article.
May 1988: Oncology Nursing Forum
https://www.readbyqxmd.com/read/2603964/early-adaptation-of-renal-magnesium-reabsorption-in-response-to-magnesium-restriction
#13
I M Shafik, G A Quamme
Dietary magnesium restriction with hypomagnesia is normally associated with diminished urinary magnesium excretion. Young rats were pair fed control magnesium diets (0.05% MgSO4) and magnesium-restricted diets (less than 0.01% Mg), and tubular magnesium reabsorption was assessed to determine the importance of filtered load (plasma magnesium) and to establish the presence of cellular adaptation of magnesium transport. Urinary magnesium excretion decreased from 17.2 +/- 2.7 to 5.9 +/- 1.2% over 20 h on low-magnesium diets without a change in plasma concentration (0...
December 1989: American Journal of Physiology
https://www.readbyqxmd.com/read/1982229/effects-of-hypomagnesia-on-transmitter-actions-in-neocortical-slices
#14
H el-Beheiry, E Puil
1. The effects of hypomagnesia on the neuronal responses induced by iontophorectically applied acetylcholine, glutamate, N-methylaspartate (NMDA) and gamma-aminobutyric acid (GABA) were investigated using intracellular recording techniques in in vitro slices of sensorimotor cortex (guinea-pigs). 2. Perfusion with Mg-free media, with or without tetrodotoxin (TTX), induced a small hyperpolarization (approximately 4 mV) and a small decrease (approximately 10%) in the input resistance of neurones. During TTX-blockade of Na-spike genesis, spontaneous depolarizing waves of low frequencies were observed in neurones of slices under Mg-free conditions...
December 1990: British Journal of Pharmacology
https://www.readbyqxmd.com/read/1578414/bulimia-nervosa-associated-physical-problems
#15
REVIEW
S L Hofland, P O Dardis
1. Bulimia involves more serious problems than previously thought. Bulimia nervosa is a psychiatric disorder characterized by binge eating followed by some form of combination of purging, including laxative or diuretic use, strenuous exercise, and self-induced vomiting to eliminate unwanted calories. 2. Physical problems of bulimia include oral and neck problems, metabolic acid-base imbalances, volume depletion, hypochloremia, hypokalemia, hyponatremia, hypomagnesia, hypocalcemia, hyperuricemia, gastrointestinal problems, and edema...
February 1992: Journal of Psychosocial Nursing and Mental Health Services
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