keyword
MENU ▼
Read by QxMD icon Read
search

Pelvic binding

keyword
https://www.readbyqxmd.com/read/28056433/pelvic-organ-prolapse-and-endogenous-circulating-sex-steroids-in-postmenopausal-women-a-case-control-study
#1
Barbara Bodner-Adler, Klaus Bodner, Cora Schneidinger, Oliver Kimberger, Ksenia Halpern, Heinz Koelbl, Wolfgang Umek
OBJECTIVE: We compared sex steroid levels of postmenopausal patients with symptomatic pelvic organ prolapse (POP) with postmenopausal matched patients without any sign of POP. Furthermore, we evaluated a possible relationship between sex steroid levels and various urogynecologic parameters in cases with POP. Main outcome of interest were differences in circulating estradiol levels between the two groups. STUDY DESIGN: We conducted a case-control study and 46 postmenopausal women with symptomatic POP≥stage 2 were matched 1:1 with 46 urogynecologic healthy women...
December 26, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28013423/cloning-expression-profiling-and-promoter-functional-analysis-of-bone-morphogenetic-protein-6-and-7-in-tongue-sole-cynoglossus-semilaevis
#2
Qian Ma, Wenrong Feng, Zhimeng Zhuang, Shufang Liu
Bone morphogenetic proteins (BMPs) play crucial roles in vertebrate developmental process and are associated with the mechanisms which drive early skeletal development. As a first approach to elucidating the role of BMPs in regulating fish bone formation and growth, we describe the cloning, expression profiling and promoter functional analysis of bmp6 and bmp7 in tongue sole (Cynoglossus semilaevis). The full length of bmp6 and bmp7 cDNA sequences is 1939 and 1836 bp, which encodes a protein of 428 and 427 amino acids, respectively...
December 24, 2016: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/27995742/tracking-the-amphibian-pathogens-batrachochytrium-dendrobatidis-and-batrachochytrium-salamandrivorans-using-a-highly-specific-monoclonal-antibody-and-lateral-flow-technology
#3
Michael J Dillon, Andrew E Bowkett, Michael J Bungard, Katie M Beckman, Michelle F O'Brien, Kieran Bates, Matthew C Fisher, Jamie R Stevens, Christopher R Thornton
The fungus Batrachochytrium dendrobatidis (Bd) causes chytridiomycosis, a lethal epizootic disease of amphibians. Rapid identification of the pathogen and biosecurity is essential to prevent its spread, but current laboratory-based tests are time-consuming and require specialist equipment. Here, we describe the generation of an IgM monoclonal antibody (mAb), 5C4, specific to Bd as well as the related salamander and newt pathogen Batrachochytrium salamandrivorans (Bsal). The mAb, which binds to a glycoprotein antigen present on the surface of zoospores, sporangia and zoosporangia, was used to develop a lateral-flow assay (LFA) for rapid (15 min) detection of the pathogens...
December 19, 2016: Microbial Biotechnology
https://www.readbyqxmd.com/read/27974754/the-seahorse-genome-and-the-evolution-of-its-specialized-morphology
#4
Qiang Lin, Shaohua Fan, Yanhong Zhang, Meng Xu, Huixian Zhang, Yulan Yang, Alison P Lee, Joost M Woltering, Vydianathan Ravi, Helen M Gunter, Wei Luo, Zexia Gao, Zhi Wei Lim, Geng Qin, Ralf F Schneider, Xin Wang, Peiwen Xiong, Gang Li, Kai Wang, Jiumeng Min, Chi Zhang, Ying Qiu, Jie Bai, Weiming He, Chao Bian, Xinhui Zhang, Dai Shan, Hongyue Qu, Ying Sun, Qiang Gao, Liangmin Huang, Qiong Shi, Axel Meyer, Byrappa Venkatesh
Seahorses have a specialized morphology that includes a toothless tubular mouth, a body covered with bony plates, a male brood pouch, and the absence of caudal and pelvic fins. Here we report the sequencing and de novo assembly of the genome of the tiger tail seahorse, Hippocampus comes. Comparative genomic analysis identifies higher protein and nucleotide evolutionary rates in H. comes compared with other teleost fish genomes. We identified an astacin metalloprotease gene family that has undergone expansion and is highly expressed in the male brood pouch...
December 14, 2016: Nature
https://www.readbyqxmd.com/read/27965446/chlamydia-trachomatis-is-resistant-to-inclusion-ubiquitination-and-associated-host-defense-in-gamma-interferon-primed-human-epithelial-cells
#5
Arun K Haldar, Anthony S Piro, Ryan Finethy, Scott T Espenschied, Hannah E Brown, Amanda M Giebel, Eva-Maria Frickel, David E Nelson, Jörn Coers
: The cytokine gamma interferon (IFN-γ) induces cell-autonomous immunity to combat infections with intracellular pathogens, such as the bacterium Chlamydia trachomatis The present study demonstrates that IFN-γ-primed human cells ubiquitinate and eliminate intracellular Chlamydia-containing vacuoles, so-called inclusions. We previously described how IFN-γ-inducible immunity-related GTPases (IRGs) employ ubiquitin systems to mark inclusions for destruction in mouse cells and, furthermore, showed that the rodent pathogen Chlamydia muridarum blocks ubiquitination of its inclusions by interfering with mouse IRG function...
December 13, 2016: MBio
https://www.readbyqxmd.com/read/27843216/the-peritoneal-scaffold-technique-of-extended-pelvic-lymph-node-dissection-during-radical-prostatectomy-a-novel-technique
#6
Chiruvella Mallikarjuna, Prasant Nayak, Syed Mohammed Ghouse, K Purnachandra Reddy, Deepak Reddy Ragoori, M T Bendigeri, Siva Reddy
INTRODUCTION: Laparoscopic or robotic-assisted laparoscopic radical prostatectomy (RALP) is a frequently used approach for localized carcinoma prostate. For intermediate and high-risk cancers, extended pelvic lymph node dissection (e-PLND), is often performed. Conventional e-PLND involves piecemeal retrieval of lymphatic tissue. We describe a novel technique of laparoscopic e-PLND, which involves en-masse removal of pelvic lymph nodes from each side, based on an overlying peritoneal scaffold...
October 2016: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/27773569/loss-and-re-emergence-of-legs-in-snakes-by-modular-evolution-of-sonic-hedgehog-and-hoxd-enhancers
#7
Francisca Leal, Martin J Cohn
Limb reduction and loss are hallmarks of snake evolution. Although advanced snakes are completely limbless, basal and intermediate snakes retain pelvic girdles and small rudiments of the femur. Moreover, legs may have re-emerged in extinct snake lineages [1-5], suggesting that the mechanisms of limb development were not completely lost in snakes. Here we report that hindlimb development arrests in python embryos as a result of mutations that abolish essential transcription factor binding sites in the limb-specific enhancer of Sonic hedgehog (SHH)...
October 19, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/27588175/matrix-metalloproteinase-3-gene-promoter-polymorphisms-a-potential-risk-factor-for-pelvic-organ-prolapse
#8
Charalampos Karachalios, Panagiotis Bakas, Georgios Kaparos, Styliani Demeridou, Ilias Liapis, Charalampos Grigoriadis, Aggelos Liapis
Pelvic organ prolapse (POP) is a common multifactorial condition. Matrix metalloproteinases (MMPs) are enzymes capable of breaking down various connective tissue elements. Single-nucleotide polymorphisms (SNPs) in regulatory areas of MMP-encoding genes can alter their transcription rate, and therefore the possible effect on pelvic floor supporting structures. The insertion of an adenine (A) base in the promoter of the MMP-3 gene at position -1612/-1617 produces a sequence of six adenines (6A), whereas the other allele has five (5A)...
September 2016: Biomedical Reports
https://www.readbyqxmd.com/read/27405583/combination-of-the-non-invasive-tests-for-the-diagnosis-of-endometriosis
#9
REVIEW
Vicki Nisenblat, Lucy Prentice, Patrick M M Bossuyt, Cindy Farquhar, M Louise Hull, Neil Johnson
BACKGROUND: About 10% of women of reproductive age suffer from endometriosis, a costly chronic disease causing pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but is expensive and carries surgical risks. Currently, there are no non-invasive tests available in clinical practice to accurately diagnose endometriosis. This review assessed the diagnostic accuracy of combinations of different non-invasive testing modalities for endometriosis and provided a summary of all the reviews in the non-invasive tests for endometriosis series...
July 13, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27386634/influence-of-radiation-exposure-during-radiotherapy-evidence-for-the-increase-of-versican-and-heparin-binding-egf-like-growth-factor-concentrations
#10
Mahmut Kemal Ozbilgin, Caner Aktas, Elgin Turkoz Uluer, Mustafa Cagatay Buyukuysal, Manuchehr Salehi Gareveran, Cengiz Kurtman
OBJECTIVE: To investigate the reaction of versican and heparin-binding EGF-like growth factor (HB-EGF) molecule concentrations to acute radiation exposure in normal bladder and rectal tissue samples in order to gain more insight into the effects of cancer radiotherapy. STUDY DESIGN: Four groups with 6 male adult Swiss Albino mice per group were investigated. The mice bladder and rectum tissue samples were subjected to a 10-Gy single-dose radiation exposure in the pelvic region with a Co-60 teletherapy device and investigated 1, 2, and 7 days after radiation exposure, with 1 reference group which was not exposed to radiation...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27328805/detection-of-quantitative-trait-loci-for-maternal-traits-using-high-density-genotypes-of-blonde-d-aquitaine-beef-cattle
#11
Alexis Michenet, Marine Barbat, Romain Saintilan, Eric Venot, Florence Phocas
BACKGROUND: The genetic determinism of the calving and suckling performance of beef cows is little known whereas these maternal traits are of major economic importance in beef cattle production systems. This paper aims to identify QTL regions and candidate genes that affect maternal performance traits in the Blonde d'Aquitaine breed. Three calving performance traits were studied: the maternal effect on calving score from field data, the calving score and pelvic opening recorded in station for primiparous cows...
2016: BMC Genetics
https://www.readbyqxmd.com/read/27296974/the-glp-1-receptor-agonists-exendin-4-and-liraglutide-alleviate-oxidative-stress-and-cognitive-and-micturition-deficits-induced-by-middle-cerebral-artery-occlusion-in-diabetic-mice
#12
Ping-Chia Li, Li-Fen Liu, Ming-Jia Jou, Hao-Kuang Wang
BACKGROUND: Glucagon-like peptide 1 (GLP-1) analogs protect a variety of cell types against oxidative damage and vascular and neuronal injury via binding to GLP-1 receptors. This study aimed to investigate the effects of the GLP-1 analogs exendin-4 and liraglutide on cerebral blood flow, reactive oxygen species production, expression of oxidative stress-related proteins, cognition, and pelvic sympathetic nerve-mediated bladder contraction after middle cerebral artery occlusion (MCAO) injury in the db/db mouse model of diabetes...
2016: BMC Neuroscience
https://www.readbyqxmd.com/read/26917262/camp-response-element-binding-3-like-protein-1-creb3l1-is-required-for-decidualization-and-its-expression-is-decreased-in-women-with-endometriosis
#13
J I Ahn, J-Y Yoo, T H Kim, Y I Kim, S D Ferguson, A T Fazleabas, S L Young, B A Lessey, J Y Ahn, J M Lim, J-W Jeong
Endometriosis is a major cause of infertility and pelvic pain, affecting more than 10% of reproductive-aged women. Progesterone resistance has been observed in the endometrium of women with this disease, as evidenced by alterations in progesterone-responsive gene and protein expression. cAMPResponse Element-Binding 3-like protein 1 (Creb3l1) has previously been identified as a progesterone receptor (PR) target gene in mouse uterus via high density DNA microarray analysis. However, CREB3L1 function has not been studied in the context of endometriosis and uterine biology...
2016: Current Molecular Medicine
https://www.readbyqxmd.com/read/26843116/serum-androgen-levels-and-sexual-function-before-and-one-year-after-treatment-of-uterine-cervical-cancer-a-pilot-study
#14
Åsa H Everhov, Angelique Flöter Rådestad, Tommy Nyberg, Karin E Smedby, Karin Bergmark, Angelica Lindén Hirschberg
INTRODUCTION: Radiotherapy or radical hysterectomy with salpingo-oophorectomy (SOE) as treatment for uterine cervical cancer causes estrogen deprivation in premenopausal women. The effects on androgen production have rarely been examined but could be relevant for survivors of cervical cancer because insufficiency has been associated with low sexual function. AIM: To investigate the effects of pelvic radiotherapy, hysterectomy with SOE, or surgery without SOE on androgen levels and to explore potential associations with sexual function...
March 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/26777049/a-novel-de-novo-gata-binding-protein-3-mutation-in-a-turkish-boy-with-hypoparathyroidism-deafness-and-renal-dysplasia-syndrome
#15
Gül Yeşiltepe Mutlu, Heves Kırmızıbekmez, Akie Nakamura, Maki Fukami, Şükrü Hatun
Hypoparathyroidism, deafness, and renal dysplasia (HDR; OMIM 146255) syndrome is a rare disease, inherited dominantly and found to be related with GATA3 (GATA binding protein 3) gene mutations. A 13-year and 8-month-old boy who presented with hypocalcemia was diagnosed with hypoparathyroidism. He also had dysmorphic facial features, renal anomaly (pelvic kidney), and mild sensorineural hearing loss. His cranial computed tomography revealed multiple calcifications in bilateral centrum semiovale, corona radiata, and basal ganglions suggesting a persistent hypoparathyroidism...
December 2015: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/26582037/dietary-conjugated-linoleic-acids-increase-intramuscular-fat-deposition-and-decrease-subcutaneous-fat-deposition-in-yellow-breed-%C3%A3-simmental-cattle
#16
Haibo Zhang, Xianwen Dong, Zhisheng Wang, Aiming Zhou, Quanhui Peng, Huawei Zou, Bai Xue, Lizhi Wang
This study was conducted to estimate the effect of dietary conjugated linoleic acids (CLA) on intramuscular and subcutaneous fat deposition in Yellow Breed × Simmental cattle. The experiment was conducted for 60 days. The results showed that the average backfat thickness, (testicles + kidney + pelvic) fat percentage and subcutaneous fat percentage in dietary CLA were significantly lower than in the control group, while intramuscular the fat percentage was significantly higher. Compared to the control group, the Longissimus muscle enzyme activities of lipoprotein lipase (LPL), fatty acid synthase (FAS) and acetyl-coenzyme A carboxylase (ACC) in dietary CLA and the subcutaneous fat enzyme activities of LPL, hormone-sensitive lipase (HSL) and carnitine palmitoyltransferase-1 (CPT-1) were significantly increased...
April 2016: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/26563122/biphasic-%C3%A2-%C3%A2-ga-psma-hbed-cc-pet-ct-in-patients-with-recurrent-and-high-risk-prostate-carcinoma
#17
Carsten-Oliver Sahlmann, Birgit Meller, Caroline Bouter, Christian Oliver Ritter, Philipp Ströbel, Joachim Lotz, Lutz Trojan, Johannes Meller, Sameh Hijazi
PURPOSE: Binding of (68)Ga-PSMA-HBED-CC ((68)Ga-PSMA) at prostate cancer (PC) cells increases over time. A biphasic protocol may help separating benign from tumor lesions. The aim of this study was the retrospective evaluation of a diagnostic incremental value of a dual-time point (biphasic) (68)Ga-PSMA-PET/CT in patients with prostate cancer. METHODS: Retrospective analysis of 35 consecutive patients (49-78 years, median 71) with newly diagnosed PC (12/35) or recurrence of PC (23/35)...
May 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/26453052/differential-expression-of-upstream-stimulatory-factor-usf-2-variants-in-eutopic-endometria-from-women-with-endometriosis-estradiol-regulation
#18
Jazmin Castro, Germán Araya, Pamela Inostroza, Paulina Hidalgo, Reinaldo González-Ramos, Hugo Sovino, M Angélica Boric, Ariel Fuentes, M Cecilia Johnson
BACKGROUND: Endometriosis, pro-inflammatory and invasive benign disease estrogen dependent, abnormally express in endometria the enzyme P450Arom, positively regulated by steroid factor-1 (SF-1). Our objective was to study the nuclear protein contents of upstream stimulating factor 2 (USF2a and USF2b), a positive regulator of SF-1, throughout the menstrual cycle in eutopic endometria from women with and without (control) endometriosis and the involvement of nuclear estrogen receptors (ER) and G-coupled protein estrogen receptor (GPER)-1...
2015: Biological Research
https://www.readbyqxmd.com/read/26122105/the-neisseria-gonorrhoeae-obg-protein-is-an-essential-ribosome-associated-gtpase-and-a-potential-drug-target
#19
Ryszard A Zielke, Igor H Wierzbicki, Benjamin I Baarda, Aleksandra E Sikora
BACKGROUND: Neisseria gonorrhoeae (GC) is a Gram-negative pathogen that most commonly infects mucosal surfaces, causing sexually transmitted urethritis in men and endocervicitis in women. Serious complications associated with these infections are frequent and include pelvic inflammatory disease, ectopic pregnancy, and infertility. The incidence of gonorrhea cases remains high globally while antibiotic treatment options, the sole counter measures against gonorrhea, are declining due to the remarkable ability of GC to acquire resistance...
2015: BMC Microbiology
https://www.readbyqxmd.com/read/25956362/genome-wide-screen-of-ovary-specific-dna-methylation-in-polycystic-ovary-syndrome
#20
Ying-Ying Yu, Cui-Xiang Sun, Yin-Kun Liu, Yan Li, Li Wang, Wei Zhang
OBJECTIVE: To compare genome-wide DNA methylation profiles in ovary tissue from women with polycystic ovary syndrome (PCOS) and healthy controls. DESIGN: Case-control study matched for age and body mass index. SETTING: University-affiliated hospital. PATIENT(S): Ten women with PCOS who underwent ovarian drilling to induce ovulation and 10 healthy women who were undergoing laparoscopic sterilization, hysterectomy for benign conditions, diagnostic laparoscopy for pelvic pain, or oophorectomy for nonovarian indications...
July 2015: Fertility and Sterility
keyword
keyword
41637
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"