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https://www.readbyqxmd.com/read/29223036/study-on-temperature-and-near-infrared-driving-characteristics-of-hydrogel-actuator-fabricated-via-molding-and-3d-printing
#1
Qian Zhao, Yunhong Liang, Lei Ren, Feng Qiu, Zhihui Zhang, Luquan Ren
A hydrogel material system which was fit for molding and 3D printing was developed to fabricate bilayer hydrogel actuators with controllable temperature and near infrared laser responses. Polymerization on interface boundary of layered structure enhanced the bonding strength of hydrogel actuators. By utilizing anisotropic of microstructure along with thickness direction, bilayer hydrogel actuators fabricated via molding realized intelligent bending/shrinking responses, which guided the preparation of hydrogel ink for 3D printing...
December 2, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29222837/low-melt-bioactive-glass-reinforced-3d-printing-akermanite-porous-cages-with-highly-improved-mechanical-properties-for-lumbar-spinal-fusion
#2
Xiurong Ke, Lei Zhang, Xianyan Yang, Juncheng Wang, Chen Zhuang, Zhouwen Jin, An Liu, Tengfei Zhao, Sanzhong Xu, Changyou Gao, Zhongru Gou, Guojing Yang
Although great strides have been made in medical technology, low back/neck pain and intervertebral disc degeneration initiated from disc degenerative disease remains a clinical challenge. Within the field of regenerative medicine therapy, we have sought to improve the biomechanical transformation of spinal fusion procedures conducted using biodegradable porous implants. Specifically, we have focused on developing mechanically strong bioceramic cages for spinal fusion and functional recovery. Herein we fabricated the akermanite (AKE) ceramic-based porous cages using low-melting bioactive glass (BG) and 3D printing technology...
December 9, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29222738/ct-based-3d-printing-is-superior-to-transesophageal-echocardiography-for-pre-procedure-planning-in-left-atrial-appendage-device-closure
#3
Edinrin Obasare, Sumeet K Mainigi, D Lynn Morris, Leandro Slipczuk, Igor Goykhman, Evan Friend, Mary Rodriguez Ziccardi, Gregg S Pressman
Accurate assessment of the left atrial appendage (LAA) is important for pre-procedure planning when utilizing device closure for stroke reduction. Sizing is traditionally done with transesophageal echocardiography (TEE) but this is not always precise. Three-dimensional (3D) printing of the LAA may be more accurate. 24 patients underwent Watchman device (WD) implantation (71 ± 11 years, 42% female). All had complete 2-dimensional TEE. Fourteen also had cardiac computed tomography (CCT) with 3D printing to produce a latex model of the LAA for pre-procedure planning...
December 8, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29221976/modeling-patient-specific-deformable-mitral-valves
#4
REVIEW
Olivia Ginty, John Moore, Terry Peters, Daniel Bainbridge
Medical imaging has advanced enormously over the last few decades, revolutionizing patient diagnostics and care. At the same time, additive manufacturing has emerged as a means of reproducing physical shapes and models previously not possible. In combination, they have given rise to 3-dimensional (3D) modeling, an entirely new technology for physicians. In an era in which 3D imaging has become a standard for aiding in the diagnosis and treatment of cardiac disease, this visualization now can be taken further by bringing the patient's anatomy into physical reality as a model...
September 7, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29219124/3d-printed-adaptive-acoustic-lens-as-a-disruptive-technology-for-transcranial-ultrasound-therapy-using-single-element-transducers
#5
Guillaume Maimbourg, Alexandre Houdouin, Thomas Deffieux, Mickael Tanter, Jean-Francois Aubry
The development of multi-element arrays for better control of the shape of ultrasonic beams has opened the way for focusing through highly aberrating media, such as the human skull. As a result, the use of brain therapy with transcranial-focused ultrasound has rapidly grown. Although effective, such technology is expensive. We propose a disruptive, low-cost approach that consists of focusing a 1-MHz ultrasound beam through a human skull with a single-element transducer coupled with a tailored silicone acoustic lens cast in a 3D-printed mold and designed using computed tomography-based numerical acoustic simulation...
December 8, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29218689/preliminary-results-of-a-3d-printed-acetabular-component-in-the-management-of-extensive-defects
#6
Mustafa Citak, Lilly Kochsiek, Thorsten Gehrke, Carl Haasper, Eduardo M Suero, Hans Mau
INTRODUCTION: The treatment of extensive bone loss and massive acetabular defects can be compounded by several challenges and pitfalls. The survivorship following acetabular revision with extensive bone loss is still unsatisfactory. The goal of the present study was to analyse the outcomes of 3D-printed patient-specific acetabular components in the management of extensive acetabular defects and combined pelvic discontinuity (PD). METHODS: 9 patients underwent revision THA using 3D-printed custom acetabular components to reconstruct extensive acetabular defects...
December 4, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29217471/3d-printing-of-high-drug-loaded-dosage-forms-using-thermoplastic-polyurethanes
#7
G Verstraete, A Samaro, W Grymonpré, V Vanhoorne, B Van Snick, M N Boone, T Hellemans, L Van Hoorebeke, J P Remon, C Vervaet
It was the aim of this study to develop high drug loaded (>30%, w/w), thermoplastic polyurethane (TPU)-based dosage forms via fused deposition modelling (FDM). Model drugs with different particle size and aqueous solubility were pre-processed in combination with diverse TPU grades via hot melt extrusion (HME) into filaments with a diameter of 1.75 ± 0.05 mm. Subsequently, TPU-based filaments which featured acceptable quality attributes (i.e. consistent filament diameter, smooth surface morphology and good mechanical properties) were printed into tablets...
December 4, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29216869/horizontal-ridge-reconstruction-of-the-anterior-maxilla-using-customized-allogeneic-bone-blocks-with-a-minimally-invasive-technique-a-case-series
#8
Laurent Venet, Michel Perriat, Francesco Guido Mangano, Thomas Fortin
BACKGROUND: Different surgical procedures have been proposed to achieve horizontal ridge reconstruction of the anterior maxilla; all these procedures, however, require bone replacement materials to be adapted to the bone defect at the time of implantation, resulting in complex and time-consuming procedures. The purpose of this study was to describe how to use a 3D printed hardcopy model of the maxilla to prepare customized milled bone blocks, to be adapted on the bone defect areas using a minimally invasive subperiosteal tunneling technique...
December 8, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29216616/basics-of-compounding-3d-printing-pharmacy-applications-geometric-shape-effects-on-3d-printing
#9
Loyd V Allen
As patient therapy becomes more specialized and individualized, one applicable method of drug delivery is through 3D printing. With 3D printing, pharmacists can provide either immediate or modified drug release of either an individual drug or multiple drugs in a singledosage unit. The release rates can be varied, not only by excipients in the formulation, but also to some extent by the shapes of the finished-drug preparation. Some studies demonstrating these concepts are included in this article, along with their method of compounding using 3D printing...
September 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/29216060/inverse-conversion-algorithm-for-an-all-optical-depth-coloring-camera
#10
Sungjin Lim, Daerak Heo, Mugeon Kim, Geunseop Choi, Joonku Hahn
Three-dimensional (3D) metrology has received a lot of attention from academic and industrial communities due to its broad applications, such as 3D contents, 3D printing, and autonomous driving. The all-optical depth coloring (AODC) camera has some benefits in computation load since it extracts depth information of an object fully optically. The AODC camera represents the depth of the object as a variation of wavelength, and spectroscopy is generally required to measure the wavelength. However, in the AODC camera, the color vector in RGB color space is convertible inversely into the wavelength after projection on the normalized rgb plane because the detected spectrum through the gating part has a narrow bandwidth as a result of the width of the slit in the projection part...
December 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29215174/microscale-3d-printing-of-nanotwinned-copper
#11
Ali Behroozfar, Soheil Daryadel, S Reza Morsali, Salvador Moreno, Mahmoud Baniasadi, Rodrigo A Bernal, Majid Minary-Jolandan
Nanotwinned (nt)-metals exhibit superior mechanical and electrical properties compared to their coarse-grained and nanograined counterparts. nt-metals in film and bulk forms are obtained using physical and chemical processes including pulsed electrodeposition (PED), plastic deformation, recrystallization, phase transformation, and sputter deposition. However, currently, there is no process for 3D printing (additive manufacturing) of nt-metals. Microscale 3D printing of nt-Cu is demonstrated with high density of coherent twin boundaries using a new room temperature process based on localized PED (L-PED)...
December 7, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29215171/graphene-inks-as-versatile-templates-for-printing-tiled-metal-oxide-crystalline-films
#12
Muchun Liu, Po-Yen Chen, Robert H Hurt
There is great interest in exploiting van der Waals gaps in layered materials as confinement reaction vessels to template the synthesis of new nanosheet structures. The gallery spaces in multilayer graphene oxide, for example, can intercalate hydrated metal ions that assemble into metal oxide films during thermal oxidation of the sacrificial graphene template. This approach offers limited control of structure, however, and does not typically lead to 2D atomic-scale growth of anisotropic platelet crystals, but rather arrays of simple particles directionally sintered into porous sheets...
December 7, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29214803/shear-thinning-and-thermo-reversible-nanoengineered-inks-for-3d-bioprinting
#13
Scott A Wilson, Lauren M Cross, Charles W Peak, Akhilesh K Gaharwar
Three-dimensional (3D) printing is an emerging approach for rapid fabrication of complex tissue structures using cell-loaded bioinks. However, 3D bioprinting has hit a bottleneck in progress because of the lack of suitable bioinks that are printable, have high shape fidelity, and are mechanically resilient. In this study, we introduce a new family of nanoengineered bioinks consisting of kappa-carrageenan (κCA) and two-dimensional (2D) nanosilicates (nSi). κCA is a biocompatible, linear, sulfated polysaccharide derived from red algae and can undergo thermo-reversible and ionic gelation...
December 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29214219/3d-printing-of-bacteria-into-functional-complex-materials
#14
Manuel Schaffner, Patrick A Rühs, Fergal Coulter, Samuel Kilcher, André R Studart
Despite recent advances to control the spatial composition and dynamic functionalities of bacteria embedded in materials, bacterial localization into complex three-dimensional (3D) geometries remains a major challenge. We demonstrate a 3D printing approach to create bacteria-derived functional materials by combining the natural diverse metabolism of bacteria with the shape design freedom of additive manufacturing. To achieve this, we embedded bacteria in a biocompatible and functionalized 3D printing ink and printed two types of "living materials" capable of degrading pollutants and of producing medically relevant bacterial cellulose...
December 2017: Science Advances
https://www.readbyqxmd.com/read/29213126/tuning-alginate-bioink-stiffness-and-composition-for-controlled-growth-factor-delivery-and-to-spatially-direct-msc-fate-within-bioprinted-tissues
#15
Fiona E Freeman, Daniel J Kelly
Alginate is a commonly used bioink in 3D bioprinting. Matrix stiffness is a key determinant of mesenchymal stem cell (MSC) differentiation, suggesting that modulation of alginate bioink mechanical properties represents a promising strategy to spatially regulate MSC fate within bioprinted tissues. In this study, we define a printability window for alginate of differing molecular weight (MW) by systematically varying the ratio of alginate to ionic crosslinker within the bioink. We demonstrate that the MW of such alginate bioinks, as well as the choice of ionic crosslinker, can be tuned to control the mechanical properties (Young's Modulus, Degradation Rate) of 3D printed constructs...
December 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29210493/custom-3d-printable-silicones-with-tunable-stiffness
#16
Matthew M Durban, Jeremy M Lenhardt, Amanda S Wu, Ward Small, Taylor M Bryson, Lemuel Perez-Perez, Du T Nguyen, Stuart Gammon, James E Smay, Eric B Duoss, James P Lewicki, Thomas S Wilson
Silicone elastomers have broad versatility within a variety of potential advanced materials applications, such as soft robotics, biomedical devices, and metamaterials. A series of custom 3D printable silicone inks with tunable stiffness is developed, formulated, and characterized. The silicone inks exhibit excellent rheological behavior for 3D printing, as observed from the printing of porous structures with controlled architectures. Herein, the capability to tune the stiffness of printable silicone materials via careful control over the chemistry, network formation, and crosslink density of the ink formulations in order to overcome the challenging interplay between ink development, post-processing, material properties, and performance is demonstrated...
December 6, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29210486/4d-printed-actuators-with-soft-robotic-functions
#17
María López-Valdeolivas, Danqing Liu, Dick Jan Broer, Carlos Sánchez-Somolinos
Soft matter elements undergoing programed, reversible shape change can contribute to fundamental advance in areas such as optics, medicine, microfluidics, and robotics. Crosslinked liquid crystalline polymers have demonstrated huge potential to implement soft responsive elements; however, the complexity and size of the actuators are limited by the current dominant thin-film geometry processing toolbox. Using 3D printing, stimuli-responsive liquid crystalline elastomeric structures are created here. The printing process prescribes a reversible shape-morphing behavior, offering a new paradigm for active polymer system preparation...
December 6, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29209661/origami-lattices-with-free-form-surface-ornaments
#18
Shahram Janbaz, Niels Noordzij, Dwisetya S Widyaratih, Cornelis W Hagen, Lidy E Fratila-Apachitei, Amir A Zadpoor
Lattice structures are used in the design of metamaterials to achieve unusual physical, mechanical, or biological properties. The properties of such metamaterials result from the topology of the lattice structures, which are usually three-dimensionally (3D) printed. To incorporate advanced functionalities into metamaterials, the surface of the lattice structures may need to be ornamented with functionality-inducing features, such as nanopatterns or electronic devices. Given our limited access to the internal surfaces of lattice structures, free-form ornamentation is currently impossible...
November 2017: Science Advances
https://www.readbyqxmd.com/read/29209491/a-3d-printed-sensor-for-monitoring-biosignals-in-small-animals
#19
Sung-Joon Cho, Donghak Byun, Tai-Seung Nam, Seok-Yong Choi, Byung-Geun Lee, Myeong-Kyu Kim, Sohee Kim
Although additive manufacturing technologies, also known as 3D printing, were first introduced in the 1980s, they have recently gained remarkable popularity owing to decreased costs. 3D printing has already emerged as a viable technology in many industries; in particular, it is a good replacement for microfabrication technology. Microfabrication technology usually requires expensive clean room equipment and skilled engineers; however, 3D printing can reduce both cost and time dramatically. Although 3D printing technology has started to emerge into microfabrication manufacturing and medical applications, it is typically limited to creating mechanical structures such as hip prosthesis or dental implants...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29208374/the-application-of-3d-printing-in-the-formulation-of-multilayered-fast-dissolving-oral-films
#20
Touraj Ehtezazi, Marwan Algellay, Yamir Islam, Matt Roberts, Nicola M Dempster, Satyajit D Sarker
Fast dissolving oral films (FDFs) provide an alternative approach to increase consumer acceptance by advantage of rapid dissolution and administration without water. Usually FDFs require taste-masking agents. However, inclusion of these excipients could make developing the formulation a challenging task. Hence, this work employed fused-deposition modelling three-dimensional (FDM 3D) printing to produce single-layered (SLFDFs), or multilayered (MLFDFs) films, with taste-masking layers being separated from drug layer...
December 2, 2017: Journal of Pharmaceutical Sciences
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