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https://www.readbyqxmd.com/read/29322015/kingiodendron-pinnatum-a-pharmacologically-effective-alternative-for-saraca-asoca-in-an-ayurvedic-preparation-asokarishta
#1
Adangam Purath Shahid, Nanu Sasidharan, Sasidharan Salini, Jose Padikkala, Nair Meera, Achuthan Chathrattil Raghavamenon, Thekkekara Devassy Babu
Saraca asoca (Fabaceae) is a prime ingredient in Asokarishta, a well-known Ayurvedic preparation for gynecological ailments. Due to scarcity, adulteration or substitution of related raw drugs is a common practice in its preparation. The bark of Kingiodendron pinnatum (Roxb. ex DC.) Harms, morphologically similar to S. asoca (Asoka) is a widely used substitute. The present study aimed to evaluate the pharmacological effectiveness of K. pinnatum as an alternative for S. asoca in Asokarishta by determining the inhibitory effect of estrogen induced uterus endometrial thickening in immature female rats...
January 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29310904/synthesis-and-characterization-of-vangabhasma
#2
Babita Kale, Nilima Rajurkar
BACKGROUND: Bhasmas are unique Ayurvedic organometallic preparations used for medicinal purpose. Quality of bhasma depends upon quality of starting materials, processing ingredients, meticulous trituration and heating cycle. In Ayurveda, Vanga bhasma is traditional Indian medicine which is an organometallic preparation treated with plant extract. It is especially used in the treatments of diseases related to gastrointestinal tract and genitor urinary system. However detailed characterization studies after synthesis are important which shows authenticity of product...
January 5, 2018: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29306573/challenges-in-integrating-component-level-technology-and-system-level-information-from-ayurveda-insights-from-nmr-phytometabolomics-and-anti-hiv-potential-of-select-ayurvedic-medicinal-plants
#3
Rama Jayasundar, Somenath Ghatak, Muzamil Ashraf Makhdoomi, Kalpana Luthra, Aruna Singh, Thirumurthy Velpandian
BACKGROUND: Information from Ayurveda meeting the analytical challenges of modern technology is an area of immense relevance. Apart from the cerebral task of bringing together two different viewpoints, the question at the pragmatic level remains 'who benefits whom'. OBJECTIVE: The aim is to highlight the challenges in integration of information (Ayurvedic) and technology using test examples of Nuclear Magnetic Resonance (NMR) metabolomics and anti-HIV-1 potential of select Ayurvedic medicinal plants...
January 3, 2018: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29276113/ayurveda-and-the-science-of-aging
#4
REVIEW
Rammohan V Rao
Since time immemorial, humanity has been concerned with developing and preserving youthful vigor, and extending longevity by stopping or delaying the aging process. By 2030, one in five of the world population will be over 65 years old. Longevity and old age are accompanied with a variety of health challenges and population studies indicate that the elderly will use between three to five times more healthcare services compared to the younger population. Modern medicine has made a great deal of progress in understanding the aging process and in controlling age-associated health issues including heart attacks, strokes, diabetes, cancer, senility, and arthritis...
December 21, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29249635/study-on-physical-properties-of-ayurvedic-nanocrystalline-tamra-bhasma-by-employing-modern-scientific-tools
#5
Rakesh Kr Singh, Sanjay Kumar, Abhay Kr Aman, S M Karim, Sunil Kumar, Manoranjan Kar
BACKGROUND: Tamra Bhasma is derived from metallic copper that is recommended for different ailments of liver and spleen, dropsy, abdominal pain, heart disease, colitis, tumors, anemia, loss of appetite, tuberculosis, as well as eye problems. OBJECTIVES: The knowledge of crystallite size and active ingredients in Bhasma materials is limited restricting its use as nanomedicine in the modern era. Also, the 2015 Nobel prize in medicine has motivated many researchers towards traditional medicines...
December 15, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29248452/protective-effect-of-terminalia-chebula-against-seizures-seizure-induced-cognitive-impairment-and-oxidative-stress-in-experimental-models-of-seizures-in-rats
#6
Ritesh Kumar, Renu Arora, Amit Agarwal, Y K Gupta
ETHNOPHARMACOLOGICAL RELEVANCE: Teminalia chebula (TC) has been traditionally used in the Ayurvedic system of medicine primarily for gastrointestinal disorders. Its fruit extract has also been used to treat epilepsy and other CNS disorders. AIM OF THE STUDY: To evaluate the effect of hydroalcoholic fruit extract of Terminalia chebula (HETC) on experimental models of seizures, seizure-induced cognitive impairment and oxidative stress in rats. MATERIALS AND METHODS: In vitro antioxidant activity of HETC was evaluated by using ABTS, NO and DPPH radical scavenging assay...
December 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29245069/aqueous-extract-of-triphala-inhibits-cancer-cell-proliferation-through-perturbation-of-microtubule-assembly-dynamics
#7
Sanith Cheriyamundath, Tejashree Mahaddalkar, Shreyada N Save, Sinjan Choudhary, Ramakrishna V Hosur, Manu Lopus
Triphala (Trl) is an ayurvedic formulation used for treating disorders of the digestive, respiratory, and nervous systems. Its anticancer properties have also been documented. We studied effects of Trl on tubulin, a target protein for several anticancer drugs, and systematically elucidated a possible antiproliferative mechanism of action of Trl. Trl inhibited proliferation of HeLa (cervical adenocarcinoma), PANC-1 (pancreatic adenocarcinoma), and MDA-MB-231 (triple-negative breast carcinoma) cells in microgram quantities and strongly suppressed the clonogenicity of HeLa cells...
December 12, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29242090/the-effect-of-brahmi-vati-and-sarpagandha-ghana-vati-in-management-of-essential-hypertension-a-randomized-double-blind-controlled-clinical-study
#8
Dhanpat Mishra, Basavaraj R Tubaki
BACKGROUND: Essential hypertension (EHTN) is emerging as one of the most prevalent disorder with higher rate of complications, morbidity and mortality. Brahmi vati, an Ayurvedic medicine is explored for its efficacy in the management of EHTN. METHODS: 68 patients of age group 20-60 years, of either sex meeting the JNC 7 criteria of EHTN were randomly divided into two groups, group A and group B. Group A and group B received capsule Brahmi vati 500 mg and capsule Sarpagandha Ghana vati 500 mg respectively twice a day for 30 days...
December 11, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29239871/integrative-medicine-as-an-adjunct-to-orthopaedic-surgery
#9
James R Ficke, Nathan M Moroski, Steven D Ross, Ranjan Gupta
Patients often seek nontraditional forms of treatment, including alternative/complementary medical options, such as chiropractic care and acupuncture, to meet their personal needs. In the United States, interest has grown in methods to reduce pain and improve function through Ayurvedic medicine, which uses plant-based supplements, such as turmeric. Traditional allopathic medicine attempts to provide patients with evidence-based therapeutic regimens for their musculoskeletal conditions. Integrative medicine often is used to prevent and manage the sequelae associated with injuries and illnesses; however, competitive athletes and military personnel use complementary medicine for performance enhancement...
January 15, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29239791/in%C3%A2-vitro-flowering-in-oldenlandia-umbellata-l
#10
Shuvra Kanta Behera, Chandrasekaran Rajasekaran, S Payas, Devanand P Fulzele, C George Priya Doss, Ramamoorthy Siva
BACKGROUND: Oldenlandia umbellata L. (Indian madder) is an antique Ayurvedic Indian herb and a source of various anthraquinone derivatives. The red dye from its roots has been used in diverse applications since ancient times. OBJECTIVES: To establish reliable and effective protocols for in vitro flowering of O. umbellata. MATERIALS AND METHODS: For in vitro flowering, organogenic calli were subcultured onto Murashige and Skoog (MS) medium supplemented with various concentrations of Naphthalene acetic acid (NAA) (0...
November 24, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29239790/anti-inflammatory-profile-of-aegle-marmelos-l-correa-bilva-with-special-reference-to-young-roots-grown-in-different-parts-of-india
#11
Azad Rajaram, G R Vanaja, Preeti Vyakaranam, Aparna Rachamallu, Gorla V Reddy, Kotha Anilkumar, Kalle M Arunasree, Anurag Dhyani, Narapureddy Krishna Prasad, Sakshee Sharma, Mahesh Chandra Joshi, Gaya Prasad Kimothi, N B Brindavanam, Pallu Reddanna
BACKGROUND: Aegle marmelos (Bilva) is being used in Ayurveda for the treatment of several inflammatory disorders. The plant is a member of a fixed dose combination of Dashamoola in Ayurveda. However, the usage of roots/root bark or stems is associated with sustainability concerns. OBJECTIVES: The present study is aimed to compare the anti-inflammatory properties of different extracts of young roots (year wise) and mature parts of Bilva plants collected from different geographical locations in India, so as to identify a sustainable source for Ayurvedic formulation...
November 24, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29217884/how-harmful-can-herbal-remedies-be-a-case-of-severe-acute-tubulointerstitial-nephritis
#12
P Beniwal, N Gaur, S K Singh, N Raveendran, V Malhotra
Acute interstitial nephritis (AIN) is a condition in which acute kidney injury (AKI) is characterized by the histological finding of interstitial inflammation. Hyponidd is an ayurvedic drug containing Momordica charantia, Gymnema sylvestre, Swertia chirata, etc., used for the treatment of Type 2 diabetes mellitus (DM) and polycystic ovarian disease as an insulin sensitizer. There are no case reports of AIN caused by this drug yet. We report a biopsy-proven case of AKI due to severe AIN associated with the use of hyponidd tablet in a 60-year-old male with DM and hypertension...
November 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/29207840/evaluation-of-the-efficacy-of-g32-commercially-available-ayurvedic-preparation-in-reducing-halitosis-a-randomized-controlled-trial
#13
Snehal Patil, Shashidhar Acharya, Siddhi Hathiwala, Deepak Kumar Singhal, Samuel Raj Srinivasan, Sachin Khatri
Introduction: Oral malodour is a social malady affecting people of all the age groups. Effective management of oral malodour is the key to improve the quality of life of such people. Aim: To evaluate the effectiveness of ayurvedic medication, G32 in controlling oral malodour and comparing the effects with Chlorhexidine (CHX). Materials and Methods: This was a single blind randomized controlled trial with parallel study design conducted at a hospital in the city of Udupi in Southern India...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29165401/systematic-overview-of-bacopa-monnieri-l-wettst-dominant-poly-herbal-formulas-in-children-and-adolescents
#14
REVIEW
James D Kean, Luke A Downey, Con Stough
Background: The Ayurvedic medicinal system employs a holistic approach to health, utilising the synergistic properties of organic resources. Research into the Ayurvedic herb Bacopa monnieri (L.) Wettst. (B.monnieri) has reported improvements in cognitive outcomes in child and adult populations. The aim of current review is to systematically assess and critically summarize clinical trials investigating B.monnieri-dominant poly-herbal formulas and their effects on the cognition, memory, learning, and behaviour in children and adolescents...
November 22, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29158030/the-role-of-ayurveda-management-in-preventing-surgical-site-infections-instead-of-surgical-antibiotic-prophylaxis
#15
Subhash Yadav, Sanjay Jain, Jatinder Chaudhary, Rahul Bansal, Manoj Sharma
It is probably for the first time in the history of modern surgery that Benign Prostate Hyperplasia (BPH) surgery which belongs to 'clean contaminated' class and requires at least 3 doses of prophylactic antibiotic as per recommendations by American Urology Association, was done without the use of any as the patient had a history of severe intolerance to them. The case was an 83 year old male patient presenting with acute urinary retention. He was a known case of BPH being managed continuously on Ayurvedic therapy for many years...
October 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29156154/coconut-phytocompounds-inhibits-polyol-pathway-enzymes-implication-in-prevention-of-microvascular-diabetic-complications
#16
Devi Lekshmi Sheela, Puthiyaveetil Abdulla Nazeem, Arunaksharan Narayanankutty, R Muthangaparambil Shylaja, Sangeetha P Davis, Priyanga James, Ravisankar Valsalan, Thekkekara Devassy Babu, Achuthan C Raghavamenon
Coconut oil (CO), the primary choice of cooking purposes in the south Asian countries, is rich in medium chain saturated fatty acids, especially lauric acid (50-52%). The oil has high medicinal use in Ayurvedic system and known to contain polyphenolic antioxidants. Studies have reported that CO improves insulin sensitivity and shows hypoglycemic effect. However, there is no information regarding its effect on chronic diabetic complications including retinopathy and nephropathy is available. The secondary diabetic complications are mediated by the activation of polyol pathway, where aldose reductase (AR) plays crucial role...
December 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29153383/understanding-hypertension-in-the-light-of-ayurveda
#17
REVIEW
Maanasi Menon, Akhilesh Shukla
Different theories have been proposed to explain hypertension from an Ayurvedic perspective, but there is no consensus amongst the experts. A better understanding of the applied physiology and etio-pathogenesis of hypertension in the light of Ayurvedic principles is being attempted to fill this gap. A detailed review of available Ayurvedic literature was carried out to understand the physiology of blood pressure and etio-pathogenesis of hypertension from the perspective of Ayurveda. Many parallels were drawn from the concepts such as Shad Kriyakala (six stages of Dosha imbalance) and Avarana of Doshas (occlusion in the normal functioning of the Doshas) to the modern pathogenesis of hypertension to gain a deeper understanding of it...
November 17, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29152258/in-vitro-screening-of-neuroprotective-activity-of-indian-medicinal-plant-withania-somnifera
#18
Manjeet Singh, Charles Ramassamy
Canine cognitive dysfunction (CCD) is an age-dependent neurodegenerative condition characterised by changes in decline in learning and memory patterns. The neurodegenerative features of CCD in ageing dogs and cats are similar to human ageing and Alzheimer's disease (AD). Discovering neuroprotective disease-modifying therapies against CCD and AD is a major challenge. Strong evidence supports the role of amyloid β peptide deposition and oxidative stress in the pathophysiology of CCD and AD. In both the human and canine brain, oxidative damage progressively increases with age...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29152040/ayurvedic-drug-induced-liver-injury
#19
Kunal K Dalal, Thomas Holdbrook, Steven R Peikin
Drug induced liver injury is responsible for 50% of acute liver failure in developed countries. Ayurvedic and homeopathic medicine have been linked to liver injury. This case describes the first documented case of Punarnava mandur and Kanchnar guggulu causing drug induced liver injury. Drug induced liver injury may be difficult to diagnosis, but use of multi-modalities tools including the ACG algorithms, causative assessment scales, histological findings, and imaging, is recommended. Advanced imaging, such as magnetic resonance cholangiopancreatography, may possibly have a greater role than previously reported in literature...
November 8, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/29144788/panchakola-reduces-oxidative-stress-in-mcf-7-breast-cancer-and-hek293-cells
#20
Tooba Naz Shamsi, Romana Parveen, Sadaf Fatima
A large number of studies have proven the efficacy of ayurveda in the field of health and wellness. Panchakola, an ayurvedic formulation, is a general health tonic primarily used to cure fever, inflammation, pain, indigestion, and so on. We investigated effects of panchakola on oxidative stress in MCF-7 breast cancer and human embryonic kidney 293 (HEK293) cells. This work was performed to assess the antineoplastic and free radical-scavenging potential of aqueous extract of panchakola, a polyherbal formulation, in normal and breast cancer cell lines (i...
November 16, 2017: Journal of Dietary Supplements
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