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Ayurvedic

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https://www.readbyqxmd.com/read/28219356/bacopa-monnieri-extract-increases-rat-coronary-flow-and-protects-against-myocardial-ischemia-reperfusion-injury
#1
Sirintorn Srimachai, Sylvie Devaux, Celine Demougeot, Sarawut Kumphune, Nina D Ullrich, Ernst Niggli, Kornkanok Ingkaninan, Natakorn Kamkaew, C Norman Scholfield, Sompol Tapechum, Krongkarn Chootip
BACKGROUND: This study explored Bacopa monnieri, a medicinal Ayurvedic herb, as a cardioprotectant against ischemia/reperfusion injury using cardiac function and coronary flow as end-points. METHODS: In normal isolated rat hearts, coronary flow, left ventricular developed pressure, heart rate, and functional recovery were measured using the Langendorff preparation. Hearts were perfused with either (i) Krebs-Henseleit (normal) solution, (control), or with 30, 100 μg/ml B...
February 20, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28217554/innate-antioxidant-activity-of-some-traditional-formulations
#2
Gunpreet Kaur, Vikas Gupta, Parveen Bansal
Herbal medicine is the oldest form of healthcare known to humanity. Recently, much attention is being directed toward the use of antioxidants. There are some very commonly used Ayurvedic preparations that might have inbuilt antioxidant activity, and their therapeutic potential can be partially attributable to its antioxidant activity. Hence, it was proposed to find out antioxidant activity of such common formulations. Estimation of innate antioxidant activity of some commonly used traditional formulations. In this study, five formulations were evaluated for antioxidant activity in comparison to gallic acid (standard) using the in vitro reducing power method and superoxide radical scavenging activity by dimethyl sulfoxide method followed by calculation of scavenging activity and inhibitory concentration 50% (IC50)...
January 2017: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/28187692/rare-case-of-giant-unicystic-ameloblastoma-luminal-variant
#3
Adarsh Kudva, Abhay T Kamath, Nirmala N Rao, Jyotsna Rajan
OBJECTIVE AND IMPORTANCE: Ameloblastoma is a locally aggressive benign tumor, commonly occurring in the mandible. While giant ameloblastoma of multicystic or plexiform variant have been reported, the authors report a rare case of giant unicystic ameloblastoma of luminal variant, which was treated by compartmental resection and planned for delayed reconstruction. CLINICAL PRESENTATION: A 46 year old male patient reported to the oral surgery out-patient department with a swelling of the left side mandible region of 2 years duration...
February 10, 2017: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/28182033/preliminary-screening-of-a-classical-ayurvedic-formulation-for-anticonvulsant-activity
#4
Arnab Dhar, Santosh Kumar Maurya, Ashish Mishra, Gireesh Kumar Singh, Manoj Kumar Singh, Ankit Seth
BACKGROUND: Epilepsy is a serious and complex central nervous system disorder associated with recurrent episodes of convulsive seizures due to the imbalance between excitatory (glutamatergic) and inhibitory (GABAergic) neurotransmitters level in the brain. The available treatments are neither competent to control the seizures nor prevent progress of disease. Since ages, Herbal medicines have remained important sources of medicines in many parts of world which is evidenced through their uses in traditional systems of medicine i...
July 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/28182032/pharmacognostical-standardization-of-upodika-basella-alba-l-an-important-ayurvedic-antidiabetic-plant
#5
T R Shantha, P Patchaimal, M Prathapa Reddy, R Kishore Kumar, Devesh Tewari, Vandana Bharti, G Venkateshwarlu, A K Mangal, M M Padhi, K S Dhiman
OBJECTIVE: To establish the pharmacognostic standards for the correct identification and standardization of an important Antidiabetic plant described in Ayurveda. MATERIALS AND METHODS: Standardization was carried out on the leaf and stem of Basella alba L. with the help of the macro-morphological, microscopic, physicochemical and qualitative phytochemical studies. RESULTS: Several specific characters were identified viz. clustered calcium oxalate crystals in the cortex region, absence of trichomes, succulent, thick, mucilaginous, fibrous stem...
July 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/28182025/identity-of-%C3%A1-a%C3%A1-k%C3%A4-r%C3%A4-physalis-minima-linn-in-ayurvedic-classics-a-literature-review
#6
REVIEW
Supriya S Kallianpur, Rohit A Gokarn, N Rajashekhar
Proper identification of drugs and their use in proper doses are important for successful treatment. Physalis minima Linn commonly known as country gooseberry has anti-cancerous, anti-diabetic, analgesic, antipyretic and anti-inflammatory potentials. The present paper is aimed to ascertain the proper identity of Ṭaṅkārī (Physalis minima Linn.) in Ayurvedic classics by a meticulous search and hence a review of the drug Ṭaṅkārī (Physalis minima Linn) was carried out in the texts of Ayurveda, modern literature, journals and online publications...
July 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/28182022/is-redefining-the-ayurvedic-proprietary-medicine-required
#7
Swapnil P Borse
No abstract text is available yet for this article.
July 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/28164735/ameliorating-effect-of-celastrus-paniculatus-standardized-extract-and-its-fractions-on-3-nitropropionic-acid-induced-neuronal-damage-in-rats-possible-antioxidant-mechanism
#8
Jai Malik, Maninder Karan, Rachna Dogra
CONTEXT: Celastrus paniculatus Wild. (Celasteraceae) (CP) is a well-known Ayurvedic 'Medhya Rasayana' (nervine tonic), used extensively as a neuro-protective and memory enhancer, and in different central nervous system disorders. OBJECTIVE: To evaluate the effect of CP against 3-nitropropionic acid (3-NP) induced Huntington's disease (HD) like symptoms in Wistar male rats. MATERIALS AND METHODS: The ethanol extract of CP seeds (CPEE), prepared by maceration, was standardized on the basis of linoleic acid content (6...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28163963/evaluation-of-the-potential-effect-of-allium-sativum-momordica-charantia-eugenia-jambolana-ocimum-sanctum-and-psidium-guajava-on-intestinal-p-glycoprotein-in-rats
#9
Devendra Kumar, Neerja Trivedi, Rakesh K Dixit
AIMS/BACKGROUND: This study was evaluated synergistic effect of a polyherbal formulation (PHF) of Allium sativum L., Eugenia jambolana Lam., Momordica charantia L., Ocimum sanctum Linn., and Psidium guajava L. on p-glycoprotein (Pgp) of intestine. These five herbs were traditionally used for diabetes. These herbs are commonly present in Ayurvedic product as antidiabetics in India. MATERIALS AND METHODS: PHF was prepared by five indigenous herbs. Different doses (50, 100 and 200 mg/kg/day) of were orally administered to Sprague-Dawley rats of different groups for multiple weeks except control groups...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28160761/efficacy-of-an-ayurvedic-formulation-for-mild-to-moderate-osteoarthritis-a-phase-3-randomized-controlled-study
#10
Milind Dattatraya Modak, Mohini Prajak Barde
Context • Current treatment options offer only symptomatic pain relief for patients with osteoarthritis (OA). Thus, a need exists for effective treatment of the disability-causing disease. The proprietary polyherbal formulation, Nartana, has been used for several years for OA. Objective • The study intended to compare the benefits of the herbal formulation with those of routinely used nonsteroidal anti-inflammatory drugs (NSAIDs) for patients with mild-to-moderate OA. Design • The research team designed a phase 3, double-blind, double-dummy, randomized controlled study...
January 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28129760/anti-inflammatory-and-immuno-modulatory-studies-on-lc-ms-characterised-methanol-extract-of-gentiana-kurroo-royle
#11
Khan Mubashir, Bashir A Ganai, Khalid Ghazanfar, Seema Akbar, Bilal Rah, Mudasir Tantry, Akbar Masood
BACKGROUND: In ayurvedic traditional medicine Gentiana kurroo Royle (family; Gentianaceae) is used to treat several metabolic diseases. This plant is rich in various compounds belonging to flavonoids and glycosides. Till now little work has been carried out on immunomodulatory and anti-inflammatory potential of this plant. This study confirms the presence of bioactive compounds and evaluates the anti-inflammatory and immunomodulatory effect of this plant. METHODS: To carry out this work, the methanol extract was investigated in different doses using in vivo and in vitro models...
January 28, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28125930/from-coastal-to-global-the-transnational-flow-of-ayurveda-and-its-relevance-for-indo-african-linkages
#12
Caroline Meier Zu Biesen
Driven by long-standing ties with India, and intertwined with global market interests, a growing influx of materia medica from South Asia is currently emerging in East Africa. To compete at a global level and framed within the language of 'South-South cooperation for mutual benefit', India presents itself as an appropriate exporter of medical products suitable for African clientele. The expansion of India's medical sector into Africa is particularly relevant for Ayurvedic pharmaceuticals. Ayurveda's diaspora into Africa exemplifies the emergence of new health interventions and medical assemblages in a transnationally interconnected world and implies innovative coalitions involved in the complex promotion of local/Global Health industries...
January 26, 2017: Global Public Health
https://www.readbyqxmd.com/read/28111813/chemometric-based-identification-and-validation-of-specific-chemical-markers-for-geographical-seasonal-and-gender-variations-in-tinospora-cordifolia-stem-using-hplc-esi-qtof-ms-analysis
#13
Vikas Bajpai, Sunil Kumar, Awantika Singh, Jyotsana Singh, M P S Negi, Sumit Kumar Bag, Nikhil Kumar, Rituraj Konwar, Brijesh Kumar
INTRODUCTION: Tinospora cordifolia is a widely distributed medicinal plant used in various traditional and commercial Ayurvedic formulations. Due to the wide use of this plant it is important to know the extent of variability in the metabolite profile resulting from geographical location, season and gender. OBJECTIVE: To develop a statistical approach based on phytochemical markers for confident prediction of variations in metabolic profile and cytotoxicity due to geographical, seasonal and gender difference in T...
January 23, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28068637/assembling-of-multifunctional-latex-based-hybrid-nanocarriers-from-calotropis-gigantea-for-sustained-doxorubicin-dox-releases
#14
Periyakaruppan Pradeepkumar, Dharman Govindaraj, Murugaraj Jeyaraj, Murugan A Munusamy, Mariappan Rajan
Natural rubber Latex (Lax) is a colloidal dispersion of polymer particles in liquid and shows good biodegradable, biocompatibility, and non-toxicity. Natural polymers are the most important materials used in food packaging, micro/nano-drug delivery, tissue engineering, agriculture, and coating. In the present study, natural compounds extracted from plant Lax were designed to function as drug carriers using various surfactants via emulation and solvent evaporation method. Calotropis gigantea belongs to the family Apocynaceae and has received considerable attention in modern medicine, ayurvedeic, siddha, and traditional medicine...
January 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28066108/neuroprotective-effect-of-celastrus-paniculatus-on-chronic-stress-induced-cognitive-impairment
#15
V Bhagya, Thomas Christofer, B S Shankaranarayana Rao
OBJECTIVE: Several studies report that chronic stress results in impaired spatial learning and working memory and enhanced anxiety-like behavior. However, not many studies have looked into the possible ways of reversing stress-induced deficits. Celastrus paniculatus (CP), a traditional ayurvedic herbal medicine, was used to treat cognitive deficits in mentally retarded children. CP oil has been reported to have neuroprotective and antioxidant activities. However, the effects of CP oil on chronic stress-induced cognitive deficits are unclear...
November 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28052238/anti-psoriatic-potential-of-solanum-xanthocarpum-stem-in-imiquimod-induced-psoriatic-mice-model
#16
Komal M Parmar, Prakash R Itankar, Apurva Joshi, Satyendra K Prasad
ETHNOPHARMACOLOGICAL RELEVANCE: The plant Solanum xanthocarpum Schrad. & Wendl. (Solanaceae) is one of the members of the dashamula (ten roots) in Ayurvedic system of medicine. The stem and fruits are used as an antipyretic, antiasthmatic and is prescribed in skin infections and for relief in burning sensation in the feet accompanied by vesicular eruptions. OBJECTIVE: To scientifically validate the anti-psoriatic potential of Solanum xanthocarpum stem in Imiquimod-induced psoriatic mice model MATERIALS AND METHODS: Ethanolic stems extract of Solanum xanthocarpum (ESX) was first subjected to phytochemical screening and quantification of identified phytoconstituents, which was further standardized with the help of HPTLC using chlorogenic acid as a marker...
January 1, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28041925/complementary-and-alternative-medicine-for-management-of-premature-ejaculation-a-systematic-review
#17
REVIEW
Katy Cooper, Marrissa Martyn-St James, Eva Kaltenthaler, Kath Dickinson, Anna Cantrell, Shijie Ren, Kevan Wylie, Leila Frodsham, Catherine Hood
INTRODUCTION: Premature ejaculation (PE) is defined as ejaculation within 1 minute (lifelong PE) or 3 minutes (acquired PE), inability to delay ejaculation, and negative personal consequences. Management includes behavioral and pharmacologic approaches. AIM: To systematically review effectiveness, safety, and robustness of evidence for complementary and alternative medicine in managing PE. METHODS: Nine databases including Medline were searched through September 2015...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28040797/disease-subtype-independent-biomarkers-of-breast-cancer-chemoprevention-by-the-ayurvedic-medicine-phytochemical-withaferin-a
#18
Suman K Samanta, Anuradha Sehrawat, Su-Hyeong Kim, Eun-Ryeong Hahm, Yongli Shuai, Ruchi Roy, Subrata K Pore, Krishna B Singh, Susan M Christner, Jan H Beumer, Nancy E Davidson, Shivendra V Singh
BACKGROUND: A nontoxic chemopreventive intervention efficacious against different subtypes of breast cancer is still a clinically unmet need. The present study was undertaken to determine the efficacy of an Ayurvedic medicine phytochemical (Withaferin A, [WA]) for chemoprevention of breast cancer and to elucidate its mode of action. METHODS: Chemopreventive efficacy of WA (4 and 8 mg/kg body weight) was determined using a rat model of breast cancer induced by N-methyl-N-nitrosourea (MNU; n = 14 for control group, n = 15 for 4 mg/kg group, and n = 18 for 8 mg/kg group)...
June 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28017997/nutraceutical-properties-of-cumin-residue-generated-from-ayurvedic-industries-using-cell-line-models
#19
K B Arun, U Aswathi, V V Venugopal, T S Madhavankutty, P Nisha
Spent cumin (SC), generated from Ayurvedic industry, was evaluated for its nutraceutical potential in terms of antioxidant, antidiabetic and anticancer properties, and compared with that of the raw cumin (RC). SC and RC seeds were extracted with ethyl acetate (E) and methanol (M). SCM (methanol extract) were rich in p-coumaric acid, ferulic acid, ellagic acid and cinnamic acid (6.4445, 5.8286, 2.1519, 4.3085 mg/g dry extract). SCM reduced Fe(2+) ion (89.68 µM AA/g dry weight), scavenged DPPH radical (IC50-238...
October 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28012983/antibacterial-activity-of-14-15-dihydroajugapitin-and-8-o-acetylharpagide-isolated-from-ajuga-bracteosa-wall-ex-benth-against-human-pathogenic-bacteria
#20
Hilal A Ganaie, Md Niamat Ali, Bashir A Ganai, Maryum Meraj, Mudasar Ahmad
Ajuga bracteosa Wall ex. Benth. (Lamiaceae) commonly known as Bungle Weed has been in use since ancient times and is mentioned Ayurvedic literature. The upper ground parts of the plant are used for treatment of various diseases. The weed is credited with astringent, febrifugal, stimulant, aperient, tonic, diuretic and depurative properties and is used for the treatment of gout and rheumatism, palsy and amenorrhoea. Two compounds 1) 14, 15-dihydroajugapitin and 2) 8-o-acetylharpagide were isolated from the aerial parts of the plant and tested for antibacterial activity against various pathogenic bacteria by agar well diffusion method...
December 21, 2016: Microbial Pathogenesis
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