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https://www.readbyqxmd.com/read/28732071/the-ideas-about-advanced-life-support-and-affecting-factors-at-the-end-stage-of-life-in-a-hospital-in-turkey
#1
Turgay Albayrak, İrfan Şencan, Ömer Akça, Esra Meltem Koç, Hilal Aksoy, Selim Ünsal, İskender Bülbül, Adem Bahadır, İsmail Kasım, Rabia Kahveci, Adem Özkara
BACKGROUND: The participation of the people in health decisions may be structured in various levels. One of these is participation in decisions for the treatment. "Advanced directives" is one of the examples for the participation in decisions for the treatment. AIM: We wanted to determine the decisions on advanced life support at the end-stage of life in case of a life-threatening illness for the people themselves and their first degree relatives and the factors effecting these decisions...
2017: PloS One
https://www.readbyqxmd.com/read/28729683/a-positive-feedback-loop-mediated-by-sigma-x-enhances-expression-of-the-streptococcal-regulator-comr
#2
Rabia Khan, Roger Junges, Heidi A Åmdal, Tsute Chen, Donald A Morrison, Fernanda C Petersen
Natural transformation is used by bacteria to take up DNA from their surroundings and incorporate it into their genomes. Streptococci do so during a transient period of competence, triggered by pheromones that they produce, secrete and sense under conditions influenced by the environment. In Streptococcus mutans, Streptococcus suis, and species of the bovis, salivarius and pyogenic groups of streptococci, the pheromone XIP is sensed by the intra-cellular regulator ComR, that in turn activates the transcription of comS, encoding the XIP precursor, and of sigX, encoding the only known alternative sigma factor in streptococci...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28728463/perceived-accessibility-to-services-and-sites-among-israeli-older-adults
#3
Adi Vitman-Schorr, Liat Ayalon, Rabia Khalaila
OBJECTIVE: To explore the direct and indirect effects of settlement type (rural-kibbutz vs. urban mid-size cities) on perceived accessibility by sociospatial factors: (a) connection to the living area, (b) familiarity with the living area, (c) social participation, and (d) perceived safety of the living area. METHOD: A convenience sample of 279 older adults aged 65 and older was interviewed. Using bootstrapping, we tested the strength and significance of the conditional indirect effects of four simultaneous mediators of the relationship between settlement type and perceived accessibility...
July 1, 2017: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28717646/genetic-variation-and-its-reflection-on-posttranslational-modifications-in-frequency-clock-and-mating-type-a-1-proteins-in-sordaria-fimicola
#4
Rabia Arif, Faiza Akram, Tazeen Jamil, Hamid Mukhtar, Siu Fai Lee, Muhammad Saleem
Posttranslational modifications (PTMs) occur in all essential proteins taking command of their functions. There are many domains inside proteins where modifications take place on side-chains of amino acids through various enzymes to generate different species of proteins. In this manuscript we have, for the first time, predicted posttranslational modifications of frequency clock and mating type a-1 proteins in Sordaria fimicola collected from different sites to see the effect of environment on proteins or various amino acids pickings and their ultimate impact on consensus sequences present in mating type proteins using bioinformatics tools...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28712191/assessing-the-role-of-education-in-adult-women-s-knowledge-and-awareness-of-human-papillomavirus-and-human-papillomavirus-vaccine
#5
Humera Ismail, Sarah Rafiq, Shafia Shakoor, Muhammad Tariq Karim, Rabia Raheel
BACKGROUND: Awareness and knowledge of Human Papillomavirus (HPV) and HPV vaccine among women are not satisfactory in developing countries. The aim of this study was to assess the role of education in adult women about knowledge and awareness of human papillomavirus (HPV) and HPV vaccine. METHODS: This cross-sectional study was carried out in women aged 19- 50 years attending the out-patient waiting area of a tertiary care hospital in Karachi from August 2014 to August 2015...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28712184/service-quality-of-diagnostic-fine-needle-aspiration-cytology-in-a-tertiary-care-hospital-of-lahore-process-measure-as-patient-s-perspective
#6
Zainab Rizvi, Rabia Arshed Usmani, Amna Rizvi, Salim Wazir, Taskeen Zahra, Hafza Rasool
BACKGROUND: Quality of any service is the most important aspect for the manufacturer as well as the consumer. The primary objective of any nation's health system is to provide supreme quality health care services to its patients. The objective of this study was to assess the quality of diagnostic fine needle aspiration cytology service in a tertiary care hospital. As Patient's perspectives provide valuable information on quality of process, therefore, patient's perception in terms of satisfaction with the service was measured...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28711407/severe-neuroimaging-anomalies-are-usually-associated-with-random-x-inactivation-in-leucocytes-circulating-dna-in-x-linked-dominant-incontinentia-pigmenti
#7
Volodia Dangouloff-Ros, Smail Hadj-Rabia, Judite Oliveira Santos, Elodie Bal, Isabelle Desguerre, Manoelle Kossorotoff, Isabelle An, Asma Smahi, Christine Bodemer, Arnold Munnich, Julie Steffann, Nathalie Boddaert
Incontinentia Pigmenti (IP) is a skin disorder with neurological impairment in 30% of cases. The most common disease causing mutation is a deletion of exons 4-10 of the IKBKG gene, located on chromosome Xq28, with skewed X-chromosome inactivation in females, but few cases of random X-inactivation have been reported. We have correlated brain anomalies with X-chromosome inactivation status determined on leucocytes circulating DNA. We reviewed MRI of 18 girls with genetically proven IP. We found three patterns of MRI, normal MRI (n=5), mild white matter abnormalities with cortical and corpus callosum atrophy (n=6), and severe cortical abnormalities suggesting a vascular disease (n=7)...
July 10, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28709820/sex-dependent-difference-in-the-relationship-between-adipose-tissue-cholesterol-efflux-and-estradiol-concentrations-in-young-healthy-humans
#8
REVIEW
Fatima Iqbal, William J Durham, Ayyash Melhem, Saleem Raslan, Tony T Tran, Traver J Wright, Rabia Asghar, Ken Fujise, Elena Volpi, Labros Sidossis, Nicola Abate, Melinda Sheffield-Moore, Demidmaa Tuvdendorj
BACKGROUND: Impaired adipose tissue function and lower levels of high density lipoprotein cholesterol (HDL-C) have been implicated in the development of vascular dementia, and metabolic diseases such as hypertension, atherosclerosis, type 2 diabetes (T2D) and metabolic syndrome. Interestingly, both the substrate fluxes in adipose tissue and HDL-C concentration differ between men and women. Moreover, adipose tissue cholesterol efflux has been implicated in modulation of HDL-C levels. Thus, we aimed to determine if the association between serum estradiol levels and adipose tissue cholesterol efflux is sex-dependent...
July 11, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28709631/neurodevelopmental-profiles-of-children-with-congenital-heart-disease-at-school-age
#9
Nadja Naef, Rabia Liamlahi, Ingrid Beck, Vera Bernet, Hitendu Dave, Walter Knirsch, Beatrice Latal
OBJECTIVES: To assess 6-year neurodevelopmental outcomes in a current cohort of children with congenital heart disease (CHD) who underwent cardiopulmonary bypass surgery (CPB), and to determine risk factors for adverse outcomes. STUDY DESIGN: Outcomes were examined in 233 prospectively enrolled children with CHD (including 64 with a recognized genetic disorder) who underwent CPB between 2004 and 2009. Follow-up assessment included standardized neurologic, motor, and cognitive tests...
July 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28706763/comparison-of-knowledge-attitudes-and-practices-of-educated-and-uneducated-adults-regarding-human-immunodeficiency-virus-in-karachi-pakistan
#10
Zainab Ahmad, Sara Sadiq, Mariam Asghar, Alizay Rashid Khan, Omer Arif, Syed Hamza Shah, Shahrukh Nadeem, Yamna Waseem, Rafi Aibani, Ammar Salman Syed, Rabia M Mustafa, Zainab Abdulrahman, Kaneez Fatima
BACKGROUND: Despite the high prevalence of human immunodeficiency virus (HIV) in Pakistan, no prior work has been done to specifically highlight the importance of education as a social vaccine against HIV. Therefore, our study focuses on differences in knowledge and practices regarding HIV and acquired immunodeficiency syndrome (AIDS) among educated and uneducated adults. METHODOLOGY: A cross-sectional study was carried out in which data was collected from all over Karachi...
June 12, 2017: Curēus
https://www.readbyqxmd.com/read/28702068/hyperglycemia-induced-oxidative-stress-and-heart-disease-cardioprotective-effects-of-rooibos-flavonoids-and-phenylpyruvic-acid-2-o-%C3%AE-d-glucoside
#11
REVIEW
Phiwayinkosi V Dludla, Elizabeth Joubert, Christo J F Muller, Johan Louw, Rabia Johnson
Diabetic patients are at an increased risk of developing heart failure when compared to their non-diabetic counter parts. Accumulative evidence suggests chronic hyperglycemia to be central in the development of myocardial infarction in these patients. At present, there are limited therapies aimed at specifically protecting the diabetic heart at risk from hyperglycemia-induced injury. Oxidative stress, through over production of free radical species, has been hypothesized to alter mitochondrial function and abnormally augment the activity of the NADPH oxidase enzyme system resulting in accelerated myocardial injury within a diabetic state...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28701773/trim21-is-critical-for-survival-of-toxoplasma-gondii-infection-and-localises-to-gbp-positive-parasite-vacuoles
#12
Clémence Foltz, Anna Napolitano, Rabia Khan, Barbara Clough, Elizabeth M Hirst, Eva-Maria Frickel
Interferon gamma (IFNγ) is the major proinflammatory cytokine conferring resistance to the intracellular vacuolar pathogen Toxoplasma gondii by inducing the destruction of the parasitophorous vacuole (PV). We previously identified TRIM21 as an IFNγ-driven E3 ubiquitin ligase mediating the deposition of ubiquitin around pathogen inclusions. Here, we show that TRIM21 knockout mice were highly susceptible to Toxoplasma infection, exhibiting decreased levels of serum inflammatory cytokines and higher parasite burden in the peritoneum and brain...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28694110/predictors-of-in-hospital-mortality-after-decompressive-hemicraniectomy-for-malignant-ischemic-stroke
#13
Saadat Kamran, Abdul Salam, Naveed Akhtar, Aymen Alboudi, Arsalan Ahmad, Rabia Khan, Rashed Nazir, Muhammad Nadeem, Jihad Inshasi, Ahmed ElSotouhy, Ghanim Al Sulaiti, Ashfaq Shuaib
OBJECTIVE: The purpose of this retrospective multicenter, pooled-data analysis was to determine the factors associated with in-hospital mortality in decompressive hemicraniectomy (DHC) for malignant middle cerebral artery (MMCA) stroke. PATIENTS AND METHODS: The authors reviewed pooled DHC database from 3 countries for patients with MMCA with hospital mortality in spite of DHC to identify factors that predicted in-hospital mortality after DHC. The identified factors were applied to the group of patients who were selected for DHC but either refused surgery and died or stabilized and did not undergo DHC...
July 7, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28691769/automatic-recognition-of-the-xlhed-phenotype-from-facial-images
#14
Smail Hadj-Rabia, Holm Schneider, Elena Navarro, Ophir Klein, Neil Kirby, Kenneth Huttner, Lior Wolf, Melanie Orin, Sigrun Wohlfart, Christine Bodemer, Dorothy K Grange
X-linked hypohidrotic ectodermal dysplasia (XLHED) is a genetic disorder that affects ectodermal structures and presents with a characteristic facial appearance. The ability of automated facial recognition technology to detect the phenotype from images was assessed . In Phase 1 of this study we examined if the age of male patients affected the technology's recognition. In Phase 2 we investigated how well the technology discriminated affected males cases from female carriers and from individuals with other ectodermal dysplasia syndromes...
July 10, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28683165/the-cyclopropyl-group-an-excited-state-aromaticity-indicator
#15
Rabia Ayub, Raffaello Papadakis, Kjell Jorner, Burkhard Zietz, Henrik Ottosson
The cyclopropyl (cPr) group, a well-known probe for radical character at atoms to which it is connected, is tested as an indicator for aromaticity in the first ππ* triplet and singlet excited states (T1 and S1). Baird's rule tells that the π-electron counts for aromaticity and antiaromaticity in the T1 and S1 states are opposite to Hückel's rule in the ground state (S0). Our hypothesis is that the cPr group, as a result of Baird's rule, will remain closed when attached to an excited state aromatic ring, enabling it to be used as an indicator to distinguish excited state aromatic rings from excited state antiaromatic and nonaromatic ones...
July 6, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28680312/motor-and-non-motor-symptoms-in-parkinson-s-disease-effects-on-quality-of-life
#16
Elif Gökçal, Veysel Eren Gür, Rabia Selvitop, Gülsen Babacan Yildiz, Talip Asil
INTRODUCTION: This study aimed to evaluate motor and non-motor symptoms in idiopathic Parkinson's disease (IPD) patients and to determine the self-reported influence of all existing symptoms on their quality of life (QoL). METHODS: The sociodemographic and clinical characteristics, medical treatments, and Modified Hoehn and Yahr (mH&Y) scores of IPD patients without cognitive impairment were recorded. A survey questioning different motor and non-motor symptoms was administered to the patients...
June 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28679931/professional-values-among-female-nursing-students-in-saudi-arabia
#17
Rabia S Allari, Samantha Ismaile, Mowafa Househ
Professional values are essential to nursing practice because they guide standards for working, provide a structure for evaluating behavior, and influence decisions making. The purpose of this study is to explore the perception of Saudi female nursing students on professional values and to assess the correlation between their perception of professional values in relation to their year of academic studies. We used a cross-sectional descriptive study where a survey was administered to 150 Saudi female nurses living in Riyadh...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28679577/learning-through-debate-during-problem-based-learning-an-active-learning-strategy
#18
Sadaf Mumtaz, Rabia Latif
We explored medical student's views and perceptions of a series of debates conducted during problem-based learning (PBL) practiced as a part of the Spiral curriculum at the Imam Abdulrahman Bin Faisal University, Saudi Arabia. A series of debates were employed during PBL sessions for second-year female medical students, over the period 2014-2016. Each cohort of students was randomly split into 10 small PBL groups and exposed to weekly PBL activity. Within each group, the students were divided into a proposition half and an opposition half...
September 1, 2017: Advances in Physiology Education
https://www.readbyqxmd.com/read/28677648/advancing-point-of-care-poc-testing-using-human-saliva-as-liquid-biopsy
#19
REVIEW
Rabia Sannam Khan, Zohaib Khurshid, Faris Yahya Ibrahim Asiri
Salivary diagnostics is an emerging field for the encroachment of point of care technology (PoCT). The necessity of the development of point-of-care (PoC) technology, the potential of saliva, identification and validation of biomarkers through salivary diagnostic toolboxes, and a broad overview of emerging technologies is discussed in this review. Furthermore, novel advanced techniques incorporated in devices for the early detection and diagnosis of several oral and systemic diseases in a non-invasive, easily-monitored, less time consuming, and in a personalised way is explicated...
July 4, 2017: Diagnostics
https://www.readbyqxmd.com/read/28669351/a-systematic-review-of-the-processes-used-to-link-clinical-trial-registrations-to-their-published-results
#20
Rabia Bashir, Florence T Bourgeois, Adam G Dunn
BACKGROUND: Studies measuring the completeness and consistency of trial registration and reporting rely on linking registries with bibliographic databases. In this systematic review, we quantified the processes used to identify these links. METHODS: PubMed and Embase databases were searched from inception to May 2016 for studies linking trial registries with bibliographic databases. The processes used to establish these links were categorised as automatic when the registration identifier was available in the bibliographic database or publication, or manual when linkage required inference or contacting of trial investigators...
July 3, 2017: Systematic Reviews
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