Anna Kobsar, Karina Koehnlechner, Philipp Klingler, Marius Niklaus, Julia Zeller-Hahn, Angela Koessler, Katja Weber, Markus Boeck, Juergen Koessler
Storage of platelet concentrates (PC) at cold temperature (CT) is discussed as an alternative to the current standard of storage at room temperature (RT). Recently, we could show that cold-induced attenuation of inhibitory signaling is an important mechanism promoting platelet reactivity. For developing strategies in blood banking, it is required to elucidate the time-dependent onset of facilitated platelet activation. Thus, freshly prepared platelet-rich-plasma (PRP) was stored for 1 and 2 h at CT (2-6 °C) or at RT (20-24 °C), followed by subsequent comparative analysis...
October 7, 2022: Scientific Reports