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Femoral artery blood flow

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https://www.readbyqxmd.com/read/29155934/controlled-flow-diversion-in-hybrid-venoarterial-venous-extracorporeal-membrane-oxygenation
#1
Mehmet Cakici, Fatih Gumus, Evren Ozcinar, Cagdas Baran, Onat Bermede, Mustafa Bahadir Inan, Mustafa Serkan Durdu, Mustafa Sirlak, Ahmet Ruchan Akar
OBJECTIVES: Patients on venoarterial or venovenous extracorporeal membrane oxygenation (ECMO) support may require venoarterial-venous (VAV-ECMO) configuration during follow-up. We report 12 cases of VAV-ECMO with significant outflow steal. METHODS: Between October 2014 and November 2016, a total of 97 patients (56.6 ± 12.0 years; 59 men/38 women; body surface area 1.84 ± 0.36 m 2 ) were supported with venoarterial ECMO ( n  = 85) or venovenous ECMO ( n  = 12)...
August 16, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29140571/is-overactive-bladder-microvasculature-disease-a-component-of-systemic-atheroscleorosis
#2
Ahmet Ozgur Yeniel, Ahmet Mete Ergenoglu, Reci Meseri, Erkan Kismali, Anıl Ari, Gulgun Kavukcu, Hikmet H Aydin, Handan Ak, Sevcan Atay, Ismail Mete Itil
AIMS: To evaluate the relationship between overactive bladder (OAB) and systemic atherosclerosis in a cohort of women. METHODS: In this case-control study, we assessed atherosclerosis indicators, such as Framingham risk scores and carotid and femoral artery intima-media thickness, and evaluated possible bladder wall responses to atherosclerosis using endovaginal color Doppler ultrasound and the detection of urinary cytokines in women with OAB and in controls. Quantitative assessment of blood perfusion at the bladder neck was performed using a method that allows for the dynamic monitoring of flow in a predefined region of interest at every point of the cardiac cycle...
November 15, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29131007/proteinase-activated-receptor-2-sensitivity-of-amplified-trpa1-activity-in-skeletal-muscle-afferent-nerves-and-exercise-pressor-reflex-in-rats-with-femoral-artery-occlusion
#3
Jihong Xing, Jianhua Li
BACKGROUND/AIMS: Limb ischemia occurs in peripheral artery disease (PAD). Sympathetic nerve activity (SNA) that regulates blood flow directed to the ischemic limb is exaggerated during exercise in this disease, and transient receptor potential channel A1 (TRPA1) in thin-fiber muscle afferents contributes to the amplified sympathetic response. The purpose of the present study was to determine the role of proteinase-activated receptor-2 (PAR2) in regulating abnormal TRPA1 function and the TRPA1-mediated sympathetic component of the exercise pressor reflex...
November 6, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29130338/colonic-hydrogen-sulfide-produces-portal-hypertension-and-systemic-hypotension-in-rats
#4
Tomasz Huc, Halina Jurkowska, Maria Wróbel, Kinga Jaworska, Maksymilian Onyszkiewicz, Marcin Ufnal
Hydrogen sulfide, a toxic gas, at low concentrations is also a biological mediator in animals. In the colon, hydrogen sulfide is produced by intestinal tissues and gut sulfur bacteria. Gut-derived molecules undergo liver metabolism. Portal hypertension is one of the most common complications contributing to the high mortality in liver cirrhosis. We hypothesized that the colon-derived hydrogen sulfide may affect portal blood pressure. Sprague-Dawley rats were maintained either on tap water (controls) or on water solution of thioacetamide to produce liver cirrhosis (CRH-R)...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29124548/development-of-an-experimental-and-digital-cardiovascular-arterial-model-for-transient-hemodynamic-and-postural-change-studies-a-preliminary-framework-analysis
#5
Rodward L Hewlin, John P Kizito
The ultimate goal of the present work is to aid in the development of tools to assist in the treatment of cardiovascular disease. Gaining an understanding of hemodynamic parameters for medical implants allow clinicians to have some patient-specific proposals for intervention planning. In the present work an experimental and digital computational fluid dynamics (CFD) arterial model consisting of a number of major arteries (aorta, carotid bifurcation, cranial, femoral, jejunal, and subclavian arteries) were fabricated to study: (1) the effects of local hemodynamics (flow parameters) on global hemodynamics (2) the effects of transition from bedrest to upright position (postural change) on hemodynamics, and (3) diffusion of dye (medical drug diffusion simulation) in the arterial system via experimental and numerical techniques...
November 9, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29122964/enhanced-muscle-blood-flow-with-intermittent-pneumatic-compression-of-the-lower-leg-during-plantar-flexion-exercise-and-recovery
#6
Kathryn A Zuj, Chekema N Prince, Richard L Hughson, Sean D Peterson
This study tested the hypothesis that intermittent compression of the lower limb would increase blood flow during exercise and post-exercise recovery. Data were collected from 12 healthy individuals (8 men) who performed three minutes of standing plantar flexion exercise. Three conditions were tested: no applied compression (NoComp), compression during the exercise period only (ExComp), and compression during two minutes of standing post-exercise recovery (RecComp). Doppler ultrasound was used to determine superficial femoral artery (SFA) blood flow responses...
November 9, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29105676/-endovascular-treatment-of-a-celiac-trunk-aneurysm-a-case-report-and-review-of-the-literature
#7
Nicola Pellizzari, Luca Ferretto, Davide Lanzellotti, Filippo Marzot, Sandro Irsara, Carlo Cernetti
Celiac trunk aneurysms are uncommon vascular lesions; treatment is usually an open surgical operation; in the medical literature, only few cases of celiac aneurysm treated with endovascular technique are reported; coil positioning or stent-graft placement are described using a femoral vascular access as first choice.Here we describe the case of a 57-year-old man with an asymptomatic large celiac trunk aneurysm involving the origin of the splenic, left gastric and hepatic arteries. The patient was treated in an elective clinical setting with a totally endovascular procedure performed through the left radial artery...
November 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29098705/intrauterine-growth-restriction-results-in-persistent-vascular-mismatch-in-adulthood
#8
Anderson H Kuo, Cun Li, Hillary F Huber, Geoffrey D Clarke, Peter W Nathanielsz
Maternal nutrient reduction induces intrauterine growth restriction (IUGR), increasing risks of chronic diseases later in life, including cardiovascular dysfunction. Using ultrasound, we determined regional blood flow, blood vessels sizes, and distensibility in IUGR baboons (8M/8F, 8.8 years, similar to 35 human years) and controls (12M/12F, 9.5 years). The measured blood vessels were larger in size in the males compared to females before but not after normalization to body surface area. Smaller IUGR normalized blood vessel sizes were observed in the femoral and external iliac arteries but not the brachial or common carotid arteries and not correlated significantly with birth weight...
November 3, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29096356/salvianolic-acid-a-attenuates-limb-ischemia-reperfusion-injury-in-skeletal-muscle-of-rats
#9
Yijia Xiang, Shiyong Ye, Changhong Cai, Junchong Chen, Xuyong Zhao, Ning Zhu, Chunlai Zeng
Ischemia and reperfusion(I/R) injury can cause complications in applying blood flow treatment for atherosclerosis occlusion syndrome. Platelet activation and inflammatory reaction play a role in the procession of I/R injury. This study was designed to investigate the effects of Salvianolic Acid A(SAA) on limb I/R injury via inhibition of platelet activation and inflammatory reaction. Rats were divided into sham, I/R, I/R+SAA-Low (5mg/kg) and I/R+SAA-high (10mg/kg) groups with a procession of 6h for ischemia and 24h for reperfusion in the femoral artery of the right hind limb, with the exception of the sham group...
October 30, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29096037/evaluation-of-pharmacokinetic-models-for-perfusion-imaging-with-dynamic-contrast-enhanced-magnetic-resonance-imaging-in-porcine-skeletal-muscle-using-low-molecular-weight-contrast-agents
#10
Stefan Hindel, Giorgos Papanastasiou, Peter Wust, Marc Maaß, Anika Söhner, Lutz Lüdemann
PURPOSE: Pharmacokinetic models for perfusion quantification with a low-molecular-weight contrast agent (LMCA) in skeletal muscle using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) were evaluated. METHODS: Tissue perfusion was measured in seven regions of interest (ROIs) placed in the total hind leg supplied by the femoral artery in seven female pigs. DCE-MRI was performed using a 3D gradient echo sequence with k-space sharing. The sequence was acquired twice, first after LMCA and then after blood pool contrast agent injection...
November 2, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29081492/tissue-engineered-small-vessel-conduits-the-anti-thrombotic-effect-of-re-endothelialization-of-decellularized-baboon-arteries-a-preliminary-experimental-study
#11
Muriel Meiring, Mmakgabu Khemisi, Leana Laker, Pascal M Dohmen, Francis E Smit
BACKGROUND The use of decellularized biological scaffolds for the reconstruction of small-diameter vascular grafts remains a challenge in tissue engineering. Thrombogenicity is an important cause of obstruction in these vessels due to decellularization. Seeding of the decellularized vascular constructs with endothelial cells is therefore a prerequisite for the prevention of thrombosis. The aim of this study was to seed decellularized baboon arteries with endothelial cells and to compare the thrombogenicity to that of decellularized arteries after circulation of blood...
October 30, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/29080996/impact-of-local-heating-and-cooling-on-skeletal-muscle-transcriptional-response-related-to-myogenesis-and-proteolysis
#12
Roksana B Zak, B M Hassenstab, L K Zuehlke, M W S Heesch, R J Shute, T L Laursen, D T LaSalle, D R Slivka
PURPOSE: To determine the impact of local muscle heating and cooling on myogenic and proteolytic gene responses following resistance exercise. METHODS: Recreationally trained males (n = 12), age 25.3 ± 1.5, % body fat 13.6 ± 1.92, completed four sets of 8-12 repetitions of unilateral leg press and leg extension while heating one leg, and cooling the other. Muscle biopsies were taken from the vastus lateralis of each leg pre and 4 h post exercise. RESULTS: MyoD, FOXO1, and MuRF1 mRNA increased with exercise regardless of temperature (p < 0...
October 28, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29074590/deletion-of-at2-receptor-prevents-shp-1-induced-vegf-inhibition-and-improves-blood-flow-reperfusion-in-diabetic-ischemic-hindlimb
#13
Judith Paquin-Veillette, Farah Lizotte, Stéphanie Robillard, Raphaël Béland, Marc-André Breton, Andréanne Guay, Marc-Antoine Despatis, Pedro Geraldes
OBJECTIVE: Ischemia caused by narrowing of femoral artery is a major cause of peripheral arterial disease and morbidity affecting patients with diabetes mellitus. We have previously reported that the inhibition of the angiogenic response to VEGF (vascular endothelial growth factor) in diabetic mice was associated with the increased expression of SHP-1 (SH2 domain-containing phosphatase 1), a protein that can be activated by the AT2 (angiotensin II type 2) receptor. Deletion of AT2 receptor has been shown to promote angiogenesis within the ischemic muscle...
October 26, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29074110/evaluation-of-a-new-model-of-hind-limb-ischemia-in-rabbit
#14
Costantino Del Giudice, Gabriel Ifergan, Guillaume Goudot, Valerie Bellamy, Emmanuel Messas, Olivier Clement, Patrick Bruneval, Philippe Menasche, Marc Sapoval
OBJECTIVE: Various animal models of critical limb ischemia have been developed in the past. However, there is no animal model that can undergo endovascular treatment, while providing reproducible true critical limb ischemia with arterial ulcers and rest pain. We evaluated the efficacy of a new model of rabbit hindlimb ischemia created through a percutaneous approach using embolization with calibrated particles. METHODS: Through a percutaneous transauricular artery approach and selective catheterization of the superficial femoral artery, embolization of distal limb vessels was performed using a mixture of 300- to 500-μm calibrated microparticles (Embosphere, Merit Medical, Salt Lake City, Utah), saline solution, and iodine contrast...
October 23, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29072344/the-effect-of-sex-and-prematurity-on-the-cardiovascular-baroreflex-response-in-sheep
#15
Beth J Allison, Vivian Nguyen, Stephanie R Yiallourou, Ilias Nitsos, Mary Jane Black, Graeme R Polglase
Very preterm infants have an increased risk of cardiovascular disease, however the effects of a late preterm birth on future cardiovascular function are not known. We hypothesized that well describes impairments in heart rate variability and baroreflex sensitivity would persist into adulthood following a late preterm birth. To test this hypothesis sheep born preterm (0.9 gestation: 9M, 7F) or term (11M, 6F) underwent surgery at 14 months of age for insertion of femoral arterial and venous catheters and femoral flow probe...
October 26, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/29062385/central-nervous-system-and-limb-embolism-concurrence-due-to-atrial-myxoma-a-case-report%C3%A2
#16
Javad Salimi, Khosro Najari, Pezhman Farshidmehr, Roja Toosi, Batool Naghavi, Tayeb Ramim
Cardiac myxomas are the most common cardiac tumors with diverse nonspecific clinical manifestations. A 78-year-old man presented to the emergency department with complaints of pain and coldness of the left lower extremity. The left femoral artery pulse was detected, while the pulses of the left popliteal, dorsalis pedis, and posterior tibialis arteries were absent. No blood inflow was detected in the superficial and deep femoral, popliteal, and anterior and posterior tibialis arteries. Thrombectomy was performed, and a fatty-like mass from the bifurcation of the common femoral artery and a thrombotic mass from the proximal portion of the superficial and deep femoral arteries were removed...
July 2017: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/29060695/pwpsim-a-new-simulation-tool-of-pulse-wave-propagation-in-the-human-arterial-tree
#17
Hanguang Xiao, Mark Butlin, Isabella Tan, Alberto P Avolio
Hemodynamic simulation enhances investigations of pulse wave propagation phenomena and enables validation of new methods of pulse wave analysis. However, such simulation systems or tools are not readily available nor easily accessible. In this study, a new simulation tool of pulse wave propagation in the human arterial tree was developed based on a transmission line model (TLM). This paper describes the theory of TLM of the human arterial tree used by this simulation. The results are a display of the main functions and simulation results of this tool...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29030339/muscle-%C3%AE-adrenergic-responsiveness-during-exercise-and-atp-induced-vasodilation-in-chronic-obstructive-pulmonary-disease-patients
#18
Ulrik Winning Iepsen, Gregers Druedal Wibe Munch, Camilla Koch Ryrsø, Niels H Secher, Peter Lange, Pia Thaning, Bente Klarlund Pedersen, Stefan P Mortensen
Sympathetic vasoconstriction is blunted in exercising muscle (functional sympatholysis) but becomes attenuated with age. We tested the hypothesis that functional sympatholysis is further impaired in chronic obstructive pulmonary disease (COPD) patients. We determined leg blood flow (LBF) and calculated leg vascular conductance (LVC) during 1) femoral-arterial Tyramine infusion (evokes endogenous norepinephrine release; 1 µmol min(-1) kg leg mass(-1)); 2) one-legged knee-extensor exercise with and without Tyramine infusion (10 W and 20% of maximal workload (WLmax)); 3) ATP (0...
October 13, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28992237/impacts-of-metabolic-syndrome-scores-on-cerebrovascular-conductance-are-mediated-by-arterial-stiffening
#19
Evan P Pasha, Alex C Birdsill, Stephanie Oleson, Andreana P Haley, Hirofumi Tanaka
BACKGROUND: Individuals with metabolic syndrome (MetS) exhibit reduced cerebral blood flow. The mechanisms of this reduction remain unknown but arterial stiffening has been implicated as a contributor. We determined if MetS was associated with reduced cerebral blood flow at midlife, and if so, whether arterial stiffness was responsible for mediating their relation. METHODS: Middle-aged (40-60 years) community dwelling adults (n = 83) were studied. MetS score was calculated for each subject...
July 31, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28986360/exaggerated-cardiovascular-responses-to-treadmill-running-in-rats-with-peripheral-arterial-insufficiency
#20
J Matthew Kuczmarski, Kellee Unrath, Gail D Thomas
Patients with atherosclerotic peripheral artery disease (PAD) have an augmented pressor response to treadmill walking, but the underlying mechanisms remain poorly understood and difficult to isolate due to the confounding presence of numerous cardiovascular risk factors. In this study, we tested the hypothesis that a chronic deficit in muscle blood flow capacity would be sufficient to trigger an exaggerated pressor response to dynamic exercise. Sprague Dawley rats (5 male, 5 female) were instrumented with radiotelemetery devices in order to measure the cardiovascular responses to treadmill running before and after bilateral femoral artery ligation, which has been shown previously to reduce the blood flow capacity of the distal hindlimb muscles by >60%...
October 6, 2017: American Journal of Physiology. Heart and Circulatory Physiology
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