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Femoral artery blood flow

Umit Kervan, Sinan Sabit Kocabeyoglu, Dogan Emre Sert, Emre Aygün, Kemal Kavasoglu, Mehmet Karahan, Ertekin Utku Unal, Mustafa Pac
OBJECTIVES: The common femoral artery is the standard site for immediate vascular access when initiating adult venoarterial extracorporeal membrane oxygenation. However, this approach is fraught with problems such as femoral artery occlusion, distal limb ischemia, reperfusion injury resulting in compartment syndrome, retroperitoneal hemorrhage, thrombosis, embolization, and most importantly, pulmonary edema. Here, we show our preference of using the subclavian artery with a side graft as a different cannulation technique for outflow of extracorporeal membrane oxygenation, which can avoid complications associated with different access techniques...
October 14, 2016: Experimental and Clinical Transplantation
Y Liu, L-B Guo, J-K Xu
OBJECTIVE: These case series present a retrospective analysis of clinical effects that an allogeneic amniotic cell transplantation can have in treating 4 patients with type 2 diabetes. PATIENTS AND METHODS: Eligible diabetic patients were onset within 3 years, with fasting blood glucose > 7.0 mmol/l. Stem - cells that are collected from neonatal amniotic membrane when a child is born (2 x 107 cells) - are used for the treatment of these patients. Measured by the flow cytometry, stem cells transfer clusters of differentiation CD113 and CD34 at a high level, and through the femoral artery on the left, they are administered into the patient's pancreatic dorsal artery...
September 2016: European Review for Medical and Pharmacological Sciences
Charlotte Iacobaeus, Ellika Andolf, Malin Thorsell, Katarina Bremme, Gun JÖrneskog, Eva Östlund, Thomas Kahan
OBJECTIVE: To examine alterations in maternal vascular structure and function during normal pregnancy. METHODS: We assessed brachial and central blood pressure, pulse wave velocity and augmentation index (by pulse wave analysis and applanation tonometry), common carotid artery structure (by ultrasonography), and endothelial function in the brachial artery (by post-ischemic hyperemia induced flow mediated vasodilation and glyceryl nitrate) and in the forearm skin microcirculation (by laser Doppler perfusion imaging during iontophoretic administration of acetylcholine and sodium nitroprusside) in 52 healthy primiparous women at 14, 24 and 34 weeks of gestation, and nine months post partum...
October 12, 2016: Ultrasound in Obstetrics & Gynecology
Mohamed Ghalayini, Pierre-Yves Brun, Pascal Augustin, Elise Guivarch, Marie Pierre Dilly, Sophie Provenchere, Pierre Mordant, Yves Castier, Philippe Montravers, Dan Longrois
Competitive flows syndrome result in severe regional hypoxemia when the deoxygenated flow from the native left ventricle (LV) competes with oxygenated flow from extracorporeal life support (ECLS) pump with potentially severe consequences for the cerebral and coronary circulations. Fast correction of hypoxemia could be obtained by decreasing native LV flow by infusion of a short-acting beta-blocker (esmolol). Our purpose was to retrospectively review the efficacy of esmolol in this situation and hypothesize on the potential mechanisms of action and the associated risks...
September 2016: Journal of Extra-corporeal Technology
D A Kenwright, A J W Thomson, P W F Hadoke, T Anderson, C M Moran, G A Gray, P R Hoskins
PURPOSE: To describe a protocol for the measurement of blood flow rate in small animals and to compare flow rate measurements against measurements made using a transit time flowmeter. MATERIALS AND METHODS: Measurements were made in rat and mice using a Visualsonics Vevo 770 scanner. The flow rate in carotid and femoral arteries was calculated from the time-average maximum velocity and vessel diameter. A correction factor was applied to correct for the overestimation of velocity arising from geometric spectral broadening...
November 2015: Ultrasound Int Open
P B Rudolphi, A Recke, E A Langan, P Hunold, B K Kahle
OBJECTIVE/BACKGROUND: Hemodynamic measurements of blood flow in the common femoral vein and artery can be performed readily using duplex sonography. The ratio of venous to arterial volume flow in these vessels, the venous arterial flow index (VAFI), is increased in patients with varicose veins and/or chronic venous disease. The objective was to determine the reproducibility of sonographically measured hemodynamic flow parameters using phase contrast magnetic resonance imaging (MRI). METHODS: Based on hemodynamic volume flow measurements from the common femoral vein and artery the VAFI was calculated in seven patients with varicose veins (C2, Ep, As, Pr) and 32 healthy controls using standard duplex sonography and MRI...
September 26, 2016: European Journal of Vascular and Endovascular Surgery
Dace Reihmane, Martin Gram, Andreas Vigelsø, Jørn Wulff Helge, Flemming Dela
Physical inactivity is a major contributor to low-grade systemic inflammation. Most of the studies characterizing interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) release from exercising legs have been done in young, healthy men, but studies on inactivity in older people are lacking. The impact of 14 days of one-leg immobilization (IM) on IL-6 and TNF-α release during exercise in comparison to the contralateral control (CON) leg was investigated. Fifteen healthy men (age 68.1 ± 1.1 year (mean ± SEM); BMI 27...
November 2016: European Journal of Sport Science
Hassan Kamran, Vijay Nambi, Smita Negi, Eric Y Yang, Changyi Chen, Salim S Virani, Panos Kougias, Alan B Lumsden, Joel D Morrisett, Christie M Ballantyne, Gerd Brunner
The relation between the arterial and venous systems in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery Disease Trial was to determine the association between femoral vein (FV) volumes and measurements of peripheral artery disease. FV wall, lumen, and total volumes were quantified with fast spin-echo proton density-weighted magnetic resonance imaging scans in 79 patients with peripheral artery disease over 2 years...
August 13, 2016: American Journal of Cardiology
Bryan W Tillman, Jeremy Kelly, Tara D Richards, Alex F Chen, Albert D Donnenberg, Vera S Donnenberg, Edith Tzeng
OBJECTIVE: Vascular restenosis remains a major obstacle to long-term success after vascular intervention. Circulating progenitor cells have been implicated in restenosis, and yet it has remained unclear if these cells, particularly nonendothelial progenitors, have an active role in this pathologic process. We hypothesized that circulating CD34(+)/c-kit(+) progenitors would increase after vascular injury, mirrored by changes in the injury signal, stromal cell-derived factor 1α (sdf1α)...
October 2016: Journal of Vascular Surgery
Davide Carrara, Rosa Maria Bruno, Alessandra Bacca, Stefano Taddei, Emiliano Duranti, Lorenzo Ghiadoni, Giampaolo Bernini
BACKGROUND: Vitamin D deficiency is related to an increased prevalence of cardiovascular disease. Renin-angiotensin-aldosterone system suppression and vascular dysfunction are considered among the main mechanisms implicated in this association. However, interventional studies demonstrating that vitamin D replacement reduces circulating renin-angiotensin-aldosterone components and improves vascular function in humans are still lacking. METHODS: Thirty-three consecutive patients with essential hypertension and hypovitaminosis D underwent therapy with cholecalciferol 50 000 IU/week orally for 8 weeks...
November 2016: Journal of Hypertension
Matthew J Rossman, H Jonathan Groot, Ryan S Garten, Melissa A H Witman, Russell S Richardson
The vasodilatory response to passive leg movement (PLM) appears to provide a novel, non-invasive assessment of vascular function. However, PLM has yet to be compared to the established non-invasive assessment of vascular health, flow mediated dilation (FMD). Therefore, as an initial evaluation of the construct validity of PLM, upright seated and supine PLM as well as brachial (BA) and superficial femoral (SFA) artery FMDs were performed in 10 young (22±1) and 30 old (73±2) subjects. During upright seated PLM, the peak change in leg blood flow (∆LBF) and leg vascular conductance (∆LVC) were significantly correlated with BA (r=0...
September 16, 2016: American Journal of Physiology. Heart and Circulatory Physiology
Tania Tsatralis, Anisyah Ridiandries, Stacy Robertson, Laura Z Vanags, Yuen Ting Lam, Joanne T M Tan, Martin K C Ng, Christina A Bursill
BACKGROUND: The average population age is increasing and the incidence of age-related vascular complications is rising in parallel. Impaired wound healing and disordered ischemia-mediated angiogenesis are key contributors to age-impaired vascular complications that can lead to amputation. High-density lipoproteins (HDL) have vasculo-protective properties and augment ischemia-driven angiogenesis in young animals. We aimed to determine the effect of reconstituted HDL (rHDL) on aged mice in a murine wound healing model and the hindlimb ischemia (HLI) model...
2016: Lipids in Health and Disease
Clemens A Strohmaier, Karolina Motloch, Christian Runge, Andrea Trost, Barbara Bogner, Alexandra Kaser-Eichberger, Falk Schrödl, Markus Lenzhofer, Herbert A Reitsamer
PURPOSE: Recent histological data suggest autonomic innervation of the central retinal artery. In the present study, we investigated the effect of electrical brain stem stimulation at the superior salivatory nucleus (SSN) on the retinal vessel diameter in rats and whether nitric oxide mediates a possible effect. METHODS: Sprague-Dawley rats (n = 12) were anesthetized using pentobarbital sodium (50 mg/kg intraperitoneally). The animals were artificially ventilated and the femoral artery and vein were cannulated for blood pressure measurement and drug administration...
September 1, 2016: Investigative Ophthalmology & Visual Science
P A Stonebridge, S A Suttie, R Ross, J Dick
OBJECTIVE: Spiral laminar flow was suggested as potentially the predominant arterial blood flow pattern many years ago. Computational fluid dynamics and flow rig testing have suggested there are advantages to spiral laminar flow. The aim of this study was to identify whether spiral laminar is the predominant flow pattern in a cohort of volunteers. METHODS: This study included 42 volunteers (mean age 66.8 years). Eleven arterial sites were examined, comprising bilateral examination of the common carotid artery, internal carotid artery, external carotid artery, common femoral artery, superficial femoral artery, and the infra renal aorta...
August 26, 2016: European Journal of Vascular and Endovascular Surgery
Michihito Kyo, Shinichiro Ohshimo, Yoshiko Kida, Tatsutoshi Shimatani, Yusuke Torikoshi, Kei Suzuki, Satoshi Yamaga, Nobuyuki Hirohashi, Nobuaki Shime
BACKGROUND: Venoarterial-venous extracorporeal membrane oxygenation (VAV ECMO) configuration is a combined procedure of extracorporeal membrane oxygenation (ECMO). The proportion of cardiac and respiratory support can be controlled by adjusting arterial and venous return. Therefore, VAV ECMO can be applicable as a bridging therapy in the transition from venoarterial (VA) to venovenous (VV) ECMO. CASE PRESENTATION: We present an 11-year-old girl with chemotherapy-induced myocarditis requiring extracorporeal cardiorespiratory support...
2016: BMC Pulmonary Medicine
N Cauwenberghs, J Knez, J D'hooge, L Thijs, W Y Yang, F Haddad, J A Staessen, T Kuznetsova
OBJECTIVE: Serial imaging studies are needed to clarify the relation of change in left ventricular (LV) structure and function with arterial stiffness. In this longitudinal population study, we assessed in continuous and categorical analyses to what extent arterial properties predict alterations in echocardiographic indexes reflecting LV structure and function. DESIGN AND METHOD: In 607 participants (50.7% women; mean age, 50.7 years), using conventional echocardiography and tissue Doppler imaging, we measured LV dimensions, transmitral blood flow and mitral annular tissue Doppler velocities at baseline and after 4...
September 2016: Journal of Hypertension
H Khettab, D Campo, R Yu, N Buard, P Boutouyrie
OBJECTIVE: Measurement of arterial stiffness (AS) is still hampered by the technical skill necessary to obtain reliable measurements. It is generally considered that AS is not prone to self-measurement. We developed a non-invasive technique to assess AS from a connected bathroom scale, based on ballistocardiography (BCG) and impedance plethysmography (IPG).(Figure is included in full-text article.) DESIGN AND METHOD: :: We included 76 healthy subjects and 35 essential hypertensive, 50% women...
September 2016: Journal of Hypertension
Kasmir Ramo, Koichi Sugamura, Siobhan Craige, John F Keaney, Roger J Davis
Arterial occlusive diseases are major causes of morbidity and mortality. Blood flow to the affected tissue must be restored quickly if viability and function are to be preserved. We report that disruption of the mixed-lineage protein kinase (MLK) - cJun NH2-terminal kinase (JNK) signaling pathway in endothelial cells causes severe blockade of blood flow and failure to recover in the murine femoral artery ligation model of hindlimb ischemia. We show that the MLK-JNK pathway is required for the formation of native collateral arteries that can restore circulation following arterial occlusion...
2016: ELife
Hui C Choo, Kazunori Nosaka, Jeremiah J Peiffer, Mohammed Ihsan, Chow C Yeo, Chris R Abbiss
This study compared the effect of postexercise water immersion (WI) at different temperatures on common femoral artery blood flow (CFA), muscle (total haemoglobin; tHb) and skin perfusion (cutaneous vascular conductance; CVC), assessed by Doppler ultrasound, near-infrared spectroscopy (NIRS) and laser Doppler flowmetry, respectively. Given that heat stress may influence the vascular response during cooling, nine men cycled for 25 min at the first ventilatory threshold followed by intermittent 30-s cycling at 90% peak power until exhaustion at 32·8 ± 0·4°C and 32 ± 5% RH...
July 28, 2016: Clinical Physiology and Functional Imaging
Hideki Amano, Masaki Nakamura, Yoshiya Ito, Hiroki Kakutani, Koji Eshima, Hidero Kitasato, Shuh Narumiya, Masataka Majima
BACKGROUND: Thromboxane A synthase (TXAS) is the enzyme that converts the arachidonic acid derivative prostaglandin H2 to thromboxane A2 (TXA2). TXA2 induces platelet aggregation, vasoconstriction, and proliferation. TXAS and TXA2 receptors or thromboxane prostanoid (TP) receptors are elevated in numerous cardiovascular and inflammatory diseases. Platelets contain numerous angiogenesis stimulating factors. However, the involvement of TXAS on recovery from an ischemic condition is not well understood...
July 2016: Journal of Surgical Research
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