keyword
MENU ▼
Read by QxMD icon Read
search

Mechanical cpr

keyword
https://www.readbyqxmd.com/read/29690910/haemodynamic-outcomes-during-piston-based-mechanical-cpr-with-or-without-active-decompression-in-a-porcine-model-of-cardiac-arrest
#1
Mikkel T Steinberg, Jan-Aage Olsen, Morten Eriksen, Andres Neset, Per Andreas Norseng, Jo Kramer-Johansen, Bjarne Madsen Hardig, Lars Wik
BACKGROUND: Experimental active compression-decompression (ACD) CPR is associated with increased haemodynamic outcomes compared to standard mechanical chest compressions. Since no clinically available mechanical chest compression device is capable of ACD-CPR, we modified the LUCAS 2 (Physio-Control, Lund, Sweden) to deliver ACD-CPR, hypothesising it would improve haemodynamic outcomes compared with standard LUCAS CPR on pigs with cardiac arrest. METHODS: The modified LUCAS delivering 5 cm compressions with or without 2 cm active decompression above anatomical chest level was studied in a randomized crossover design on 19 Norwegian domestic pigs...
April 24, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/29685007/neuroprotection-of-ulinastatin-on-transient-cerebral-ischemia-via-antioxidative-mechanisms
#2
H X Hu, D H Xu, W N Ju, C Ma, X Wang, X L Liu
Ulinastatin [also called urinary trypsin inhibitor (UTI)] has beneficial effects on cerebral ischemic injury evoked by cardiac arrest (CA). However, the underlying mechanisms are unknown. The purpose of this report was to determine the involvement of antioxidative signal pathway of the hippocampus in effects of UTI in the process of neurological functions after transient cerebral ischemia. CA was induced by asphyxia followed by cardiopulmonary resuscitation in rats. Western blot analysis and ELISA were used to examine expression of Nrf2-antioxidant response element (ARE) and superoxide dismutases (SOD), and the levels of products of oxidative stress...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29665427/end-tidal-co-2-guided-automated-robot-cpr-system-in-the-pig-preliminary-communication
#3
Gil Joon Suh, Jaeheung Park, Jung Chan Lee, Sang Hoon Na, Woon Yong Kwon, Kyung Su Kim, Taegyun Kim, Yoon Sun Jung, Jung-In Ko, So Mi Shin, Kyoung Min You
BACKGROUND: Our aim was to compare the efficacy of the end-tidal CO2 -guided automated robot CPR (robot CPR) system with manual CPR and mechanical device CPR. METHODS: We developed the algorithm of the robot CPR system which automatically finds the optimal compression position under the guidance of end-tidal CO2 feedback in swine models of cardiac arrest. Then, 18 pigs after 11 minutes of cardiac arrest were randomly assigned to one of three groups, robot CPR, LUCAS CPR, and manual CPR groups (n = 6 each group)...
April 14, 2018: Resuscitation
https://www.readbyqxmd.com/read/29658608/ipsc%C3%A2-msc-inhibition-assessment-in-raw-264-7-cells-following-oxygen-and-glucose-deprivation-reveals-a-distinct-function-for-cardiopulmonary-resuscitation
#4
Yi Yu, Dongping Wang, Hui Li, Yujie Liu, Zhao Xiang, Junlin Wu, Xiaoli Jing
Hypoxia is a serious stress state. The nervous system is less tolerant to hypoxia, and cell death due to hypoxia is irreversible. With the incidence of cardiovascular disease gradually increasing, the sudden cardiac death rate is additionally increasing. Although cardiopulmonary resuscitation (CPR) is an important development, recovery is frequently poor. In a successful recovery population, ~40% of the population was in a vegetative state or subsequently succumbed to their condition, and ~20% had brain damage...
April 11, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29644580/on-the-efficacy-of-cardio-pulmonary-resuscitation-and-epinephrine-following-cyanide-and-h-2-s-intoxication-induced-cardiac-asystole
#5
Annick Judenherc-HaouzI, Takashi Sonobe, Vikhyat S Bebarta, Philippe Haouzi
This study was aimed at determining the efficacy of epinephrine, followed by chest compressions, in producing a return of spontaneous circulation (ROSC) during cyanide (CN)- or hydrogen sulfide (H2 S)-induced toxic cardiac pulseless electrical activity (PEA) in the rat. Thirty-nine anesthetized rats were exposed to either intravenous KCN (n = 27) or H2 S solutions (n = 12), at a rate that led to a PEA within less than 10 min. In the group intoxicated by CN, 20 rats were mechanically ventilated and received either epinephrine (0...
April 11, 2018: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/29626140/military-application-of-mechanical-cpr-devices-a-pressing-requirement
#6
EDITORIAL
Iain T Parsons, A T Cox, P S C Rees
Maintaining high-quality chest compressions during cardiopulmonary resuscitation following cardiac arrest presents a challenge. The currently available mechanical CPR (mCPR) devices are described in this review, coupled with an analysis of the evidence pertaining to their efficacy. Overall, mCPR appears to be at least equivalent to high-quality manual CPR in large trials. There is potential utility for mCPR devices in the military context to ensure uninterrupted quality CPR following a medical cardiac arrest...
April 6, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29616522/further-options-and-survival-results-after-failure-following-ecls-implantation
#7
Leopold Rupprecht, Daniele Camboni, Alois Philipp, Dirk Lunz, Thomas Müller, Christof Schmid, Andreas Keyser
BACKGROUND: A retrospective study was designed to analyze the outcome of patients with extracorporeal life support (ECLS) who needed a consecutive cardiac or pulmonary support system. METHODS: From 2006 to 2016, 93 out of 587 patients with their age ranging from 2.4 to 77.3 years required an exchange of an ECLS by another mechanical support system. Sixty- one patients were inhospital cases, 39 patients were referred with ECLS from other institutions by ambulance car (n=15) or helicopter (n=24)...
April 3, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29614537/-news-in-cardiopulmonary-resuscitation
#8
Guido Michels, Hans-Jörg Busch
For the first time, the european guidelines for cardiopulmonary resuscitation (CPR) have been updated by the ILCOR in december 2017. If new data and findings are available, these guidelines can also be updated outside the 5-year cycle. Thus, it is now recommended that, depending on the level of training of the layer, a chest-compression-only CPR or in combination with ventilation should be done. The important function of the dispatchers in the context of telephone or dispatcher-assisted CPR is emphasized by the demand of a structured training...
April 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29613954/left-ventricular-compressions-improve-return-of-spontaneous-circulation-and-hemodynamics-in-a-swine-model-of-traumatic-cardiopulmonary-arrest
#9
Kenton L Anderson, Kristin C Fiala, Maria G Castaneda, Susan M Boudreau, Allyson A Araña, Vikhyat S Bebarta
BACKGROUND: Prehospital cardiopulmonary resuscitation, including closed chest compressions, has commonly been considered ineffective in traumatic cardiopulmonary arrest (TCPA) because traditional chest compressions do not produce substantial cardiac output. However, recent evidence suggests that chest compressions located over the left ventricle produce greater hemodynamics when compared to traditional compressions. We hypothesized that chest compressions located directly over the left ventricle would improve return of spontaneous circulation (ROSC) and hemodynamics, when compared to traditional chest compressions, in a swine model of traumatic cardiopulmonary arrest (TCPA)...
April 2, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29611441/juvenile-cerebral-ischemia-reveals-age-dependent-bdnf-trkb-signaling-changes-novel-mechanism-of-recovery-and-therapeutic-intervention
#10
Robert M Dietz, James E Orfila, Krista M Rodgers, Olivia P Patsos, Guiying Deng, Nicholas Chalmers, Nidia Quillinan, Richard J Traystman, Paco S Herson
Global ischemia in childhood often leads to poor neurologic outcomes, including learning and memory deficits. Using our novel model of childhood cardiac arrest/cardiopulmonary resuscitation (CA/CPR), we investigate the mechanism of ischemia-induced cognitive deficits and recovery. Memory is impaired seven days after juvenile CA/CPR and completely recovers by 30 days. Consistent with this remarkable recovery not observed in adults, hippocampal long-term potentiation (LTP) is impaired 7-14 days after CA/CPR, recovering by 30 days...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29568933/effects-and-mechanism-of-amyloid-%C3%AE-1-42-on-mitochondria-in-astrocytes
#11
Yunyi Yao, Jin-Zhong Huang, Yingqi Chen, He-Juan Hu, Xiying Tang, Xianhong Li
Amyloid β (Aβ)1-42 is strongly associated with Alzheimer's disease (AD). The effects of Aβ1‑42 on astrocytes remain largely unknown. The present study focused on the effects of Aβ1‑42 on U87 human glioblastoma cells as astrocytes for in vitro investigation and mouse brains for in vivo investigation. The mechanism and regulation of mitochondria and cytochrome P450 reductase (CPR) were also investigated. As determined by MTT assays, low doses of Aβ1‑42 (<1 µM) marginally promoted astrocytosis compared with the 0 µM group within 24 h, however, after 48 h treatment these doses reduced cellular growth compared with the 0 µM group...
March 16, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29564310/fetal-doppler-to-predict-cesarean-delivery-for-non-reassuring-fetal-status-in-the-severe-small-for-gestational-age-fetuses-of-late-preterm-and-term
#12
Ji Hye Jo, Yong Hee Choi, Jeong Ha Wie, Hyun Sun Ko, In Yang Park, Jong Chul Shin
Objective: To evaluate the significance of fetal Doppler parameters in predicting adverse neonatal outcomes and the risk of cesarean delivery due to non-reassuring fetal status, in severe small for gestational age (SGA) fetuses of late preterm and term gestation. Methods: Fetal brain and umbilical artery (UmA) Doppler parameters of cerebroplacental ratio (CPR) and UmA pulsatility index (PI) were evaluated in a cohort of 184 SGA fetuses between 34 and 41 weeks gestational age, who were less than the 5th percentile...
March 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29510457/an-insidious-and-deadly-complication-of-mechanical-chest-compressions-in-a-patient-on-anticoagulation-and-the-subtle-echocardiographic-findings-that-enabled-timely-diagnosis
#13
Grace Koo, Neha Goyal, Jeanne M DeCara, Roberto M Lang, Karima Addetia
Good-quality chest compressions improve outcomes in cardiac arrest. While manual chest compressions are suboptimal in this regard, the LUCAS device has been shown to improve the effectiveness of chest compressions during cardiopulmonary resuscitation (CPR). The complication rate associated with mechanical CPR, however, has not been adequately studied. Limited evidence suggests no difference in internal injury between manual and mechanical CPR. We report the case of a patient on anticoagulation who developed a mediastinal hematoma post mechanical CPR and on whom subtle findings on initial echocardiography could have alerted the clinician to this complication early during the clinical course...
March 6, 2018: Echocardiography
https://www.readbyqxmd.com/read/29492757/glibenclamide-prevents-water-diffusion-abnormality-in-the-brain-after-cardiac-arrest-in-rats
#14
Kaibin Huang, Ziyue Wang, Yong Gu, Zhong Ji, Zhenzhou Lin, Shengnan Wang, Suyue Pan, Yongming Wu
BACKGROUND: Glibenclamide (GBC) improves neurological outcome after cardiac arrest (CA) in rats. In this study, we sought to elucidate the mechanism responsible for the neuroprotective effects of GBC by using a high-field MRI system. METHODS: Male Sprague-Dawley rats were subjected to 10-min asphyxial CA followed by cardiopulmonary resuscitation (CPR). Diffusion-weighted imaging (DWI) as well as conventional T2-weighted imaging was conducted prior to CA and at 24, 48, and 72 h after resuscitation...
February 28, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29491310/a-case-of-fulminant-type-1-diabetes-mellitus-accompanied-by-positive-conversion-of-anti-insulin-antibody-after-the-administration-of-anti-ctla-4-antibody-following-the-discontinuation-of-anti-pd-1-antibody
#15
Michiru Shiba, Hidefumi Inaba, Hiroyuki Ariyasu, Shintaro Kawai, Yuko Inagaki, Shohei Matsuno, Hiroshi Iwakura, Yuki Yamamoto, Masahiro Nishi, Takashi Akamizu
An 80-year-old woman with malignant melanoma received 20 cycles of anti-PD-1 antibody (nivolumab) treatment and showed normal glucose tolerance. Three weeks after switching to anti-CTLA-4 antibody (ipilimumab), her plasma glucose level was elevated to 639 mg/dL, her HbA1c was 7.7%, and her fastening serum CPR was undetectable. Anti-GAD and IA-2 antibodies were negative. She was diagnosed with fulminant type 1 diabetes mellitus (F1DM). Remarkably, her anti-insulin antibody was positively converted, and her KL-6 levels increased after ipilimumab therapy...
February 28, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29485991/the-dead-and-the-dying-a-difficult-part-of-ems-transport-a-swiss-cross-sectional-study
#16
Rebecca Maria Hasler, Sandra Stucky, Heinz Bähler, Aristomenis K Exadaktylos, Frank Neff
OBJECTIVE: Most deaths occur in the pre-hospital setting, whereas mortality in the emergency department (ED) is low (<1%). However, our clinical impression is that some patients are being transported to hospital in devastating conditions with no likelihood of survival, but demanding extensive hospital resources. The decision on whether to transport a dying person to hospital or not is a difficult task for emergency medical services (EMS) personnel. As there is little epidemiological data about these patients, this paper aims to describe this special population...
2018: PloS One
https://www.readbyqxmd.com/read/29481910/hypothermia-outcome-prediction-after-extracorporeal-life-support-for-hypothermic-cardiac-arrest-patients-the-hope-score
#17
Mathieu Pasquier, Olivier Hugli, Peter Paal, Tomasz Darocha, Marc Blancher, Paul Husby, Tom Silfvast, Pierre-Nicolas Carron, Valentin Rousson
AIMS: Currently, the decision to initiate extracorporeal life support for patients who suffer cardiac arrest due to accidental hypothermia is essentially based on serum potassium level. Our goal was to build a prediction score in order to determine the probability of survival following rewarming of hypothermic arrested patients based on several covariates available at admission. METHODS: We included consecutive hypothermic arrested patients who underwent rewarming with extracorporeal life support...
February 23, 2018: Resuscitation
https://www.readbyqxmd.com/read/29475945/solution-structure-of-the-cytochrome-p450-reductase-cytochrome-c-complex-determined-by-neutron-scattering
#18
Samuel L Freeman, Anne Martel, Juliette Devos, Jaswir Basran, Emma L Raven, Gordon C K Roberts
Electron transfer in all living organisms critically relies on formation of complexes between the proteins involved. The function of these complexes requires specificity of the interaction to allow for selective electron transfer but also a fast turnover of the complex and they are therefore often transient in nature, making them challenging to study. Here, using small-angle neutron scattering with contrast matching with deuterated protein, we report the solution structure of the electron transfer complex between cytochrome P450 reductase (CPR) and its electron transfer partner cytochrome c...
February 23, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29465450/gamification-in-action-theoretical-and-practical-considerations-for-medical-educators
#19
Chrystal Rutledge, Catharine M Walsh, Nathan Swinger, Marc Auerbach, Danny Castro, Maya Dewan, Mona Khattab, Alyssa Rake, Ilana Harwayne-Gidansky, Tia T Raymond, Tensing Maa, Todd P Chang
Gamification involves the application of game design elements to traditionally non-game contexts. It is increasingly being used as an adjunct to traditional teaching strategies in medical education to engage the millennial learner and enhance adult learning. The extant literature has focused on determining whether the implementation of gamification results in better learning outcomes, leading to a dearth of research examining its theoretical underpinnings within the medical education context. The authors define gamification, explore how gamification works within the medical education context using self-determination theory as an explanatory mechanism for enhanced engagement and motivation, and discuss common roadblocks and challenges to implementing gamification...
February 20, 2018: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29447297/development-of-a-decision-aid-for-cardiopulmonary-resuscitation-and-invasive-mechanical-ventilation-in-the-intensive-care-unit-employing-user-centered-design-and-a-wiki-platform-for-rapid-prototyping
#20
Ariane Plaisance, Holly O Witteman, Annie LeBlanc, Jennifer Kryworuchko, Daren Keith Heyland, Mark H Ebell, Louisa Blair, Diane Tapp, Audrey Dupuis, Carole-Anne Lavoie-Bérard, Carrie Anna McGinn, France Légaré, Patrick Michel Archambault
BACKGROUND: Upon admission to an intensive care unit (ICU), all patients should discuss their goals of care and express their wishes concerning life-sustaining interventions (e.g., cardiopulmonary resuscitation (CPR)). Without such discussions, interventions that prolong life at the cost of decreasing its quality may be used without appropriate guidance from patients. OBJECTIVES: To adapt an existing decision aid about CPR to create a wiki-based decision aid individually adapted to each patient's risk factors; and to document the use of a wiki platform for this purpose...
2018: PloS One
keyword
keyword
41601
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"