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Eunkyong Kim, Seo-Eun Cho, Kyoung-Sae Na, Han-Yong Jung, Kang-Joon Lee, Seong-Jin Cho, Dae-Guen Han
Many studies have reported that suicides tend to occur on Mondays. However, owing to a lack of controls, conclusive findings on the potential effects of a day of the week on suicides have been lacking. We analyzed public data for causes of death from 1997 to 2015 in the Republic of Korea. Accidental death was used as a control group. The probability of suicide on each day of the week according to age group was calculated. A total of 377,204 deaths (188,601 suicides and 188,603 accidental deaths) were used. The frequency of suicide was highest on Monday and decreased throughout the week until Saturday...
January 19, 2018: Suicide & Life-threatening Behavior
Jared McDowall, Ahmed Adam, Louis Gerber, Callistus O A Enyuma, Sunday J Aigbodion, Sean Buchanan, Abdullah E Laher
PURPOSE: A positive whirlpool sign (WS) is defined as the presence of a spiral-like pattern when the spermatic cord is assessed during ultrasonography (US), using standard, high-resolution ultrasonography (HRUS) and/or color Doppler sonography (CDS), in the presence of testicular torsion. The objective of this review was to assess the validity and accuracy of this sign by performing a comprehensive systematic literature review and meta-analysis. METHODS: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, a comprehensive literature search was performed (August, 2017), using the following databases: BMJ Best Practice, Cochrane Library, Embase, PubMed, Scopus, and Web of Science...
January 15, 2018: Emergency Radiology
Christopher E Sunday, Dmitry Veksler, Kin C Cheung, Yaw S Obeng
Traditional metrology has been unable to adequately address the needs of the emerging integrated circuits (ICs) at the nano scale; thus, new metrology and techniques are needed. For example, the reliability challenges in fabrication need to be well understood and controlled to facilitate mass production of through-substrate-via (TSV) enabled three-dimensional integrated circuits (3D-ICs). This requires new approaches to the metrology. In this paper, we use the microwave propagation characteristics to study the reliability issues that precede the physical damage caused by electromigration in the Cu-filled TSVs...
November 7, 2017: Journal of Applied Physics
Azmatullah Khan, Jan E Szulejko, Ki-Hyun Kim, Richard J C Brown
The concentrations of C6-C10 volatile aromatic hydrocarbons (AHCs) in air were measured at an urban air quality monitoring station in Jong-Ro, Seoul, Korea, between 2013 and 2015. Their temporal patterns (e.g., diurnal, intraweek, daily) were assessed individually and collectively as groups of benzene, toluene, ethylbenzene, styrene, and xylene (BTESX); total aliphatic hydrocarbon (TALHC: C2-C12); total aromatic hydrocarbon (TARHC: C6-C10); and total hydrocarbon (THC: C2-C12). The highest mean AHC concentrations over the 3-year study (in ppb (v/v)) were observed for toluene (6...
January 11, 2018: Journal of Environmental Management
I M Heerfordt, P A Philipsen, H C Wulf
OBJECTIVES: To prevent skin cancer, the general population is recommended to limit time in the sun, to wear clothes and to seek shade around noon. This study aimed to investigate the number of beachgoers, the duration of sun exposure, and clothing worn during the day on a beach in Copenhagen. STUDY DESIGN: Observational, descriptive study. METHODS: On 11 beach days in 2014 and 2015, beachgoers were counted every hour from 8:00 to 20:00. It was noted if they wore clothes or swimwear...
January 9, 2018: Public Health
Nidhi Rohatgi, Marlena Kane, Marcy Winget, Farnoosh Haji-Sheikhi, Neera Ahuja
Lack of collaboration between care teams and patients/families has been associated with delayed discharge from the hospital. In this study, we determine whether patients' awareness of the estimated date of discharge (EDD) was associated with a decrease in delayed discharge, and determine the factors associated with a delayed discharge. A total of 221 patients admitted to the General Medicine service between July and September 2014 were included in the study. Estimated date of discharge was identified within 36 hours of admission...
January 8, 2018: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
Chellappagounder Thangavel, Ettickan Boopathi, Yi Liu, Christopher McNair, Alex Haber, Maryna Perepelyuk, Anshul Bhardwaj, Sankar Addya, Adam Ertel, Sunday Shoyele, Ruth Birbe, Joseph M Salvino, Adam P Dicker, Karen E Knudsen, Robert B Den
The retinoblastoma tumor suppressor (RB), a key regulator of cell cycle progression and proliferation, is functionally suppressed in up to 50% of non-small cell lung cancer (NSCLC).  RB function is exquisitely controlled by a series of proteins including the CyclinD-CDK4/6 complex. In the current study, we interrogated the capacity of a CDK4/6 inhibitor, palbociclib, to activate RB function.   Experimental Design and Results: We employed multiple isogenic RB proficient and deficient NSCLC lines to interrogate the cytostatic and cytotoxic capacity of CDK 4/6 inhibition in vitro and in vivo  We demonstrate that while short term exposure to palbociclib induces cellular senescence, prolonged exposure results in inhibition of tumor growth...
January 8, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Mackenzie A Sunday, Woo-Yeol Lee, Isabel Gauthier
The presence of differential item functioning (DIF) in a test suggests bias that could disadvantage members of a certain group. Previous work with tests of visual learning abilities found significant DIF related to age groups in a car test (Lee, Cho, McGugin, Van Gulick, & Gauthier, 2015), but not in a face test (Cho et al., 2015). The presence of age DIF is a threat to the validity of the test even for studies where aging is not of interest. Here, we assessed whether this pattern of age DIF for cars and not faces would also apply to new tests targeting the same abilities with a new matching task that uses two studied items per trial...
January 1, 2018: Journal of Vision
Chrysantus Mbi Tanga, Fathiya Mbarak Khamis, Henri E Z Tonnang, Ivan Rwomushana, Gladys Mosomtai, Samira A Mohamed, Sunday Ekesi
Integrative taxonomy has resolved the species status of the potentially invasive Ceratitis rosa Karsch into two separate species with distinct ecological requirements: C. rosa "lowland type" and the newly described species Ceratitis quilicii De Meyer, Mwatawala & Virgilio sp. nov. "highland type". Both species are tephritid pests threatening the production of horticultural crops in Africa and beyond. Studies were carried out by constructing thermal reaction norms for each life stage of both species at constant and fluctuating temperatures...
2018: PloS One
Andrew M Campbell, Ralph A Hicks, Shannon L Thompson, Sarah E Wiehe
The objectives of this study were to identify intimate partner violence (IPV) incidence rates, to quantify specific risks and characteristics of these incidents and the environments in which they occur, to identify how often children are present for or injured during these incidents, and to identify differences in victim reports of IPV to law enforcement officers at the scene of the incident compared with previously published reports of IPV from retropsective, anonymous surveys and domestic violence shelter interviews...
April 1, 2017: Journal of Interpersonal Violence
Sunday Azagba
BACKGROUND: The proliferation of electronic vaping products raises many concerns, including whether these products will lead to risky behaviors among adolescents. Evidence suggests that e-cigarettes may be used to vaporize cannabis (marijuana). The current study examined associations between e-cigarette use, dual use of e-cigarettes and tobacco cigarettes, and frequency of cannabis use. METHODS: Data on high school students (grades 9-12) were from the 2014-2015 Canadian Student Tobacco, Alcohol and Drugs Survey (n=23,429 respondents)...
December 23, 2017: Addictive Behaviors
Oyeyemi O Ajayi, Sunday O Peters, Marcos De Donato, F Denis Mujibi, Waqas A Khan, Tanveer Hussain, Masroor E Babar, Ikhide G Imumorin, Bolaji N Thomas
DNAJA1 or heat shock protein 40 (Hsp40) is associated with heat adaptation in various organisms. We amplified and sequenced a total of 1,142 bp of bovine Hsp40 gene representing the critical N-terminal (NTR) and C-terminal (CTR) regions in representative samples of African, Asian and American cattle breeds. Eleven and 9 different haplotypes were observed in the NTR in Asian and African breeds respectively while in American Brangus, only two mutations were observed resulting in two haplotypes. The CTR appears to be highly conserved between cattle and yak...
2018: Journal of Genomics
Jakub Maria Antczak, Anna Poleszczyk, Adam Wichniak, Maria Rakowicz, Tadeusz Jerzy Parnowski
OBJECTIVES: Repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. In this study we investigated whether the depression-related insomnia is modulated by this therapeutic method. METHODS: We examined 13 patients (mean age 50.6±13.9; 11 women) with bipolar or unipolar depression. During 20 consecutive days, excluding Saturdays and Sundays, they underwent 20 daily sessions of 10 Hz rTMS over the left dorsolateral prefrontal cortex (DLPFC)...
October 29, 2017: Psychiatria Polska
Alice R Kininmonth, Nafeesa Jamil, Nasser Almatrouk, Charlotte E L Evans
OBJECTIVES: To investigate the quality of nutrition articles in popular national daily newspapers in the UK and to identify important predictors of article quality. SETTING: Newspapers are a primary source of nutrition information for the public. DESIGN: Newspaper articles were collected on 6 days of the week (excluding Sunday) for 6 weeks in summer 2014. Predictors included food type and health outcome, size of article, whether the journalist was named and day of the week...
December 27, 2017: BMJ Open
Katharina Schütte-Nütgen, Gerold Thölking, Maximilian Dahmen, Felix Becker, Linus Kebschull, René Schmidt, Hermann Pavenstädt, Barbara Suwelack, Stefan Reuter
The 'weekend effect' describes increased adverse outcomes after weekend hospitalization. We examined weekend-weekday differences in the outcome of 580 patients following renal transplantation (RTx, brain dead donors) between January 2007 and December 2014 at our center. 3-year patient and graft survival, incidence of delayed graft function (DGF), acute rejections and estimated glomerular filtration rate (eGFR, CKD-EPI) at 1 year as well as surgical complications were assessed. Of all 580 transplants, 416 (71...
2017: PloS One
Jacek K Urbanek, Adam P Spira, Junrui Di, Andrew Leroux, Ciprian Crainiceanu, Vadim Zipunnikov
BACKGROUND: We propose a method for estimating the timing of in-bed intervals using objective data in a large representative US sample, and quantify the association between these intervals and age, sex, and day of the week. METHODS: The study included 11,951 participants 6 years and older from the National Health and Nutrition Examination Survey (NHANES) 2003-2006, who wore accelerometers to measure physical activity for seven consecutive days. Participants were instructed to remove the device just before the nighttime sleep period and put it back on immediately after...
December 28, 2017: Chronobiology International
Andrew McCarthy
In February 2017, the Fair Work Commission (FWC) handed down a decision which cut penalty rates for employees in the retail, hospitality and fast food industries. In particular, it cut the level of penalty rates for working on Sundays and public holidays by 25% to 50%.
May 2017: Australian Nursing & Midwifery Journal
Jerry Z Yu, Connie M Rhee, Antoney Ferrey, Alex Li, Anna Jin, Yongen Chang, Uttam Reddy, Wei Ling Lau, Jason Chou, Jula Inrig, Kamyar Kalantar-Zadeh
The vast majority of maintenance dialysis patients suffer from poor long-term survival rates and lower levels of health-related quality of life. However, home hemodialysis is a historically significant dialysis modality that has been associated with favorable outcomes as well as greater patient autonomy and control, yet only represents a small minority of the total dialysis performed in the United States. Some potential disadvantages of home hemodialysis include vascular access complications, infection-related hospitalizations, patient fatigue, and attrition...
December 18, 2017: Seminars in Dialysis
Victor L Kallen, Janine H Stubbe, Henk Jan Zwolle, Pierre Valk
Background/aim: It is well known that physical strain is associated with increased cortisol production. And although mental stress elevates cortisol concentrations as well, little is known of the independent and/or combined effects of both on the secretion of cortisol. Aim of the study was to investigate the day-to-day cortisol dynamics associated with training, performance and recuperation and the immediate responses to mental stress and physical endurance under competitive conditions...
2017: BMJ Open Sport & Exercise Medicine
Martin Ezeani, Sunday Elom
The incidence of QT prolongation and torsades de pointes is on the rise due to the use of cardiovascular and non-cardiovascular drugs. Robust efforts have been made and are still ongoing to understand the underlying mechanisms that can enhance or prevent the development of drug-induced proarrhythmia. A caveat in the use of antiarrhythmic drugs is the ability to obtain safe action potential prolongation therapeutic effects, through IKr blockade. This remains as yet completely unachievable, as blockers of the potassium channel have not provided complete safe measures...
2017: Open Heart
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