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https://www.readbyqxmd.com/read/28624607/obese-asthmatics-have-decreased-surfactant-protein-a-levels-mechanisms-and-implications
#1
Njira Lugogo, Dave Francisco, Kenneth J Addison, Akarsh Manne, William Pederson, Jennifer L Ingram, Cynthia L Green, Benjamin T Suratt, James J Lee, Mary E Sunday, Monica Kraft, Julie G Ledford
BACKGROUND: Eosinophils are prominent in some individuals with asthma and are elevated in the submucosa in a subgroup of obese asthmatics. Surfactant protein-A (SP-A) modulates host responses to infectious and environmental insults. OBJECTIVE: To determine if SP-A levels are altered in obese asthma patients compared to a control group and to determine the implications of these alterations in SP-A levels in asthma. METHODS: Bronchoalveolar lavage fluid from 23 lean, 12 overweight and 20 obese subjects were examined for SP-A...
June 14, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28615855/genetic-diversity-among-trypanosoma-vivax-strains-detected-in-naturally-infected-cattle-in-nigeria-based-on-its1-of-rdna-and-diagnostic-antigen-gene-sequences
#2
Michael I Takeet, Benjamin O Fagbemi, Sunday O Peters, Marcos DeDonato, Abdul-Mojeed Yakubu, Mathew Wheto, Ikhide G Imumorin
Trypanosoma vivax (sub-genus Duttonella) is largely responsible for non profitable livestock production in sub-Sahara Africa. In Nigeria, no study has addressed the molecular characteristic of T. vivax except Y486. Hence, we characterized and assessed the genetic diversity among T. vivax detected in naturally infected cattle in Nigeria using internal transcribed spacer 1 (ITS1) of ribosoma DNA (rDNA) and diagnostic antigen gene (DAG) sequences. The length of ITS1 and DAG sequences range from 215-220 to 257-338 bp, respectively and the mean G-C contents were 60 and 61...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28602050/effect-of-hiv-infection-on-outcomes-after-surgical-repair-of-genital-fistula
#3
Steven N Shephard, Sunday J Lengmang, Stephen A Anzaku, Oluwatobi V Mamven, Carolyn V Kirschner
OBJECTIVE: To compare outcomes following surgical repair of genital fistula among Nigerian women with or without HIV. METHODS: A retrospective review was conducted of all genital fistula repair surgeries performed at Evangel Vesicovaginal Fistula Center in Jos, Nigeria, between January 1, 2004, and April 30, 2014. Patient characteristics, HIV status, genital fistula characteristics, and postoperative outcomes were assessed for between-group variance. The odds ratio (OR) and 95% confidence intervals (CIs) were the primary measures used for determining the association between HIV status and surgical outcomes...
June 11, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28594789/quickstats-average-number-of-deaths-from-motor-vehicle-injuries-suicide-and-homicide-by-day-of-the-week-national-vital-statistics-system-united-states-2015
#4
(no author information available yet)
In 2015, an average of 103 motor vehicle injury deaths, 121 suicides, and 49 homicides occurred each day. Motor vehicle injury deaths were more likely to occur on Saturdays and Sundays and least likely to occur on Tuesdays. The highest number of suicides occurred on Mondays and Tuesdays and the lowest on Saturdays. Homicides peaked on Sundays, followed by Saturdays; homicides were less likely to occur on weekdays.
June 9, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28587809/inpatient-interventions-are-infrequent-during-pediatric-hospitalizations-for-food-induced-anaphylaxis
#5
Susan A Rudders, Sunday Clark, Carlos A Camargo
No abstract text is available yet for this article.
June 3, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28584512/civilian-penetrating-gunshot-injury-to-the-neurocranium-in-enugu
#6
Ephraim Eziechina Onyia, Mark C Chikani, Wilfred C Mezue, Enoch O Uche, Izuchukwu Iloabachie, Matthew Mesi, Sunday Ejembi, Chuka Agunwa
INTRODUCTION: Civilian penetrating gunshot injuries to the neurocranium are no longer uncommon in Nigeria. Such injuries are however poorly reported. They are associated with poor outcome and, at close range, are frequently fatal, especially when inflicted by high-velocity weapons. Prompt transfer to neurosurgical service and urgent intervention may improve outcome in those that are not mortally wounded. MATERIALS AND METHODS: Fifty-two patients with civilian penetrating gunshot wounds seen over a 10-year period (2004-2014) at the University of Nigeria Teaching Hospital and Memfys Hospital for Neurosurgery Enugu were reviewed retrospectively, and their data were analyzed to evaluate factors that impacted on outcome...
January 2017: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/28583927/the-effects-of-moderate-intensity-training-in-a-hypoxic-environment-on-transcriptional-responses-in-thoroughbred-horses
#7
Allan J Davie, Li Wen, Andrew R E Cust, Rosalind Beavers, Tom Fyfe, Shi Zhou
This study investigated the effects of six weeks of normobaric hypoxic training on transcriptional expression of the genes associated with mitochondrial and glycolytic activities in Thoroughbred horses. Eight horses were divided into two groups of four. They completed an identical incremental, moderate intensity training program, except that one group trained in a hypoxic chamber with 15% oxygen for 30 minutes on alternate days except Sundays (HT), while the other group trained in normal air (NC). Prior to and post the training, heart rate and blood lactate were measured during an incremental treadmill test...
June 5, 2017: Biology Open
https://www.readbyqxmd.com/read/28574159/bladder-spasm-following-urogenital-fistula-repair
#8
Kenneth C Ekwedigwe, Maradona E Isikhuemen, Ileogben Sunday-Adeoye, Emmanuel N Yakubu, Monday O Eliboh
OBJECTIVE: To examine the occurrence of bladder spasms following surgical repair of urogenital fistula. METHODS: The present retrospective study included data from patients who underwent surgical repair of urogenital fistula at the National Obstetric Fistula Centre, Abakaliki, Nigeria, between June 1, 2015, and May 31, 2016. Patients who underwent rectovaginal fistula repair and those who experienced persistent postoperative pain requiring high doses of analgesia were excluded...
June 2, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28557844/child-deaths-of-undetermined-intent-an-analysis-of-circumstances-using-illinois-violent-death-reporting-system-data
#9
Han-Wei Wu, Suzanne G McLone, Maryann Mason, Karen Sheehan
BACKGROUND: There is little information available about the circumstances surrounding the deaths of children aged 0 to 14 in which the manner of death is of undetermined intent. METHODS: We analyzed data collected in the Illinois Violent Death Reporting System (IVDRS) to describe victim demographics, location of injury, seasonality, day of week, and circumstances surrounding the victims' deaths. RESULTS: From 2005 to 2010 in Cook County, Illinois, 192 cases were identified of children aged 0-14 years, in which the manner of death was of undetermined intent...
May 25, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28541658/characterizing-patterned-block-copolymer-thin-films-with-soft-x-rays
#10
Daniel F Sunday, Jiaxing Ren, Christopher D Liman, Lance D Williamson, Roel Gronheid, Paul F Nealey, R Joseph Kline
The directed self-assembly (DSA) of block copolymers (BCPs) is a potential solution for patterning critical features for integrated circuits at future technology nodes. For this process to be implemented, there needs to be a better understanding of how the template guides the assembly and induces subsurface changes in the lamellar structure. Using a rotational transmission X-ray scattering measurement coupled with soft X-rays to improve contrast between polymer components, the impact of the ratio of the guiding stripe width (W) to the BCP pitch (L0) was investigated...
June 6, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28529220/clinical-correlates-of-treatment-response-among-patients-with-schizophrenia-in-a-tertiary-nigerian-hospital
#11
Mark Sunday Ezeme, Richard Uwakwe, Appolos Chidi Ndukuba, Monday N Igwe, Paul Chigozie Odinka, Kennedy Amadi, Nichodemus O Obayi
A significant proportion of patients treated for schizophrenia respond poorly to medication. Few studies have systematically examined the impact of clinical characteristics of patients to antipsychotic response in our environment. The study aimed to identify clinical variables associated with response in patients with schizophrenia. A total of 172 participants diagnosed with schizophrenia, placed on antipsychotics, who presented for the first time to the hospital or have stopped medication in the preceding six months, whose responses were assessed after four to six weeks were studied...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28521719/virological-suppression-and-patterns-of-resistance-amongst-patients-on-antiretroviral-therapy-at-4-nigerian-military-hospitals
#12
Babajide Keshinro, Ojor Ayemoba, Kene Terfa, Julie Ake, Trevor A Crowell, Yakubu Adamu, Tahir Mohammed, Ifeanyi Okoye, Sunday Odeyemi, Keith Crawford, Lindsay Hughes, Ezekiel Akintunde, Tahir Umar, Tiffany E Hamm, Ogbonnaya S Njoku
BACKGROUND: In resource-constrained settings, plasma HIV-1 RNA quantification has not been routinely available for the monitoring of response to antiretroviral therapy. This study evaluated virological suppression rates amongst patients on first-line ART in four Nigerian military hospitals. METHODS: We conducted a cross-sectional study of 325 randomly selected adult clinic clients (≥18 years old) on first-line ART regimens at four Nigerian military hospitals. Plasma HIV-1 RNA was assayed using a Roche COBAS TaqMan48 with High Pure System...
May 16, 2017: Current HIV Research
https://www.readbyqxmd.com/read/28516231/molecular-evolution-of-type-ii-mage-genes-from-ancestral-maged2-gene-and-their-phylogenetic-resolution-of-basal-mammalian-clades
#13
Marcos De Donato, Sunday O Peters, Tanveer Hussain, Hectorina Rodulfo, Bolaji N Thomas, Masroor E Babar, Ikhide G Imumorin
Type II melanoma-associated antigens (MAGE) are a subgroup of about a dozen proteins found in various locations in the genome and expressed in normal tissues, thus are not related to cancer as the type I MAGE genes. This gene family exists as a single copy in non-mammals and monotremata, but found as two copies in metatherians and occur as a diverse group in all eutherians. Our studies suggest MAGED2 as the ancestor of this subfamily and the most likely evolutionary history of eutherian type II MAGE genes is hereby proposed based on synteny conservation, phylogenetic relations, genome location, homology conservation, and the protein and gene structures...
May 17, 2017: Mammalian Genome: Official Journal of the International Mammalian Genome Society
https://www.readbyqxmd.com/read/28514639/warming-induced-changes-to-body-size-stabilize-consumer-resource-dynamics
#14
Matthew M Osmond, Matthew A Barbour, Joey R Bernhardt, Matthew W Pennell, Jennifer M Sunday, Mary I O'Connor
Both body size and temperature directly influence consumer-resource dynamics. There is also widespread empirical evidence for the temperature-size rule (TSR), which creates a negative relationship between temperature and body size. However, it is not known how the TSR affects community dynamics. Here we integrate temperature- and size-dependent models to include indirect effects of warming, through changes in body size, to answer the question, How does the TSR affect the predicted response of consumer-resource systems to warming? We find that the TSR is expected to maintain consumer-resource biomass ratios and buffer the community from extinctions under warming...
June 2017: American Naturalist
https://www.readbyqxmd.com/read/28512116/weekday-and-survival-after-cardiac-surgery-a-swedish-nationwide-cohort-study-in-106%C3%A2-473-patients
#15
Magnus Dalén, Gustaf Edgren, Torbjörn Ivert, Martin J Holzmann, Ulrik Sartipy
BACKGROUND: The purpose of this study was to investigate the association between weekday of surgery and survival following cardiac surgery. METHODS AND RESULTS: In a nationwide cohort study, we included all patients who underwent cardiac surgery in 1999-2013 from the SWEDEHEART (Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies) register. All-cause mortality until March 2014 was obtained from national registers...
May 16, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28507612/pattern-of-injuries-in-fatal-motorcycle-accidents-seen-in-lagos-state-university-teaching-hospital-an-autopsy-based-study
#16
Francis Faduyile, Festus Emiogun, Sunday Soyemi, Olugbenga Oyewole, Uche Okeke, Oluseun Williams
BACKGROUND: Deaths from motorcycle accident injuries have remained a major public health issue in Nigeria over the years. AIM: The study is to determine the age and gender distribution of the victims and to identify the cause of death and the anatomical pattern of injuries seen. METHODOLOGY: This is a 5-year autopsy-based study of all motorcycle accident deaths seen in Lagos State University Teaching Hospital between December 2009 and November 2014...
April 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28499548/mortality-risks-associated-with-emergency-admissions-during-weekends-and-public-holidays-an-analysis-of-electronic-health-records
#17
A Sarah Walker, Amy Mason, T Phuong Quan, Nicola J Fawcett, Peter Watkinson, Martin Llewelyn, Nicole Stoesser, John Finney, Jim Davies, David H Wyllie, Derrick W Crook, Tim E A Peto
BACKGROUND: Weekend hospital admission is associated with increased mortality, but the contributions of varying illness severity and admission time to this weekend effect remain unexplored. METHODS: We analysed unselected emergency admissions to four Oxford University National Health Service hospitals in the UK from Jan 1, 2006, to Dec 31, 2014. The primary outcome was death within 30 days of admission (in or out of hospital), analysed using Cox models measuring time from admission...
May 9, 2017: Lancet
https://www.readbyqxmd.com/read/28497412/improved-mortality-outcomes-over-time-for-weekend-emergency-medical-admissions
#18
R Conway, S Cournane, D Byrne, D O'Riordan, B Silke
BACKGROUND: Multiple studies have suggested an association between weekend hospital admissions and mortality. These have been limited by potential residual confounders and a lack of explanation of causation. AIM: We previously attributed adverse weekend outcomes to higher acuity; we have re-examined this question for all emergency medical admissions to our institution from 2002 to 2014. METHODS: We divided admissions by a weekday or weekend (Friday to Sunday) hospital arrival...
May 11, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28478963/shoulder-and-elbow-pain-in-elementary-school-baseball-players-the%C3%A2-results-from-a-nation-wide-survey-in-japan
#19
Kenji Takagishi, Tetsuya Matsuura, Takashi Masatomi, Etsuo Chosa, Tsuyoshi Tajika, Mikihiko Watanabe, Tetsu Iwama, Toshiro Otani, Katsunori Inagaki, Hiroyasu Ikegami, Mitsuhiro Aoki, Ko Kato, Toru Okuwaki, Koichi Sairyo, Yasushi Kameyama, Akira Maeda, Moroe Beppu
BACKGROUND: Despite recommendations on how to prevent baseball injuries in youths by the Japanese Society of Clinical Sports Medicine, shoulder and elbow pain still frequently occurs in young baseball players. We conducted a questionnaire survey among baseball players at elementary schools across the country to understand the practice conditions of players, examining the risk factors of shoulder and elbow pain in baseball players. METHODS: The questionnaire survey was conducted among elementary school baseball players as members of the Baseball Federation of Japan in September 2015...
May 3, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28476362/editorial-commentary-core-muscle-injuries-or-athletic-pubalgia-finally-the-real-sausage-not-just-the-same-ole-baloney
#20
EDITORIAL
William C Meyers
In their paper "Prevalence of Surgical Repair for Athletic Pubalgia and Impact on Performance in Football Athletes Participating in the National Football League Combine," Knapik et al. cut through the baloney in the literature on "sports hernia" and apply new eyes to the impact of the results of core muscle surgery on young elite athletes trying out for the National Football League (NFL). They found that the players who had surgery did just as well as all the others in and following NFL Combines. Even the players with presumptively residual, MRI findings did well...
May 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
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