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https://www.readbyqxmd.com/read/29933274/driving-under-the-influence-of-cannabis-a-framework-for-future-policy
#1
Robert M Chow, Bryan Marascalchi, Winfred B Abrams, Nathalie A Peiris, Charles A Odonkor, Steven P Cohen
Marijuana is the most widely consumed illicit substance in the United States, and an increasing number of states have legalized it for both medicinal and recreational purposes. As it becomes more readily available, there will be a concurrent rise in the number of users and, consequently, the number of motor vehicle operators driving under the influence. This article examines the cognitive and psychomotor effects of cannabis, as well as current policy concerning driving under the influence of drugs. The authors performed a MEDLINE search on the epidemiology of cannabis use, its cognitive and psychomotor effects, and policies regarding driving under the influence of drugs...
June 20, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29933254/contact-buzz-allergic-contact-dermatitis-to-cannabis
#2
Erin Foster, Christina Nguyen, Patricia Norris
No abstract text is available yet for this article.
June 21, 2018: Dermatitis
https://www.readbyqxmd.com/read/29930974/an-examination-of-the-impact-of-childhood-emotional-abuse-and-gender-on-cannabis-use-trajectories-among-community-youth
#3
Anne N Banducci, Julia W Felton, Marcel O Bonn-Miller, C W Lejuez
Cannabis is the most frequently used illicit substance among youth, with rates of cannabis use escalating across adolescence. One potential factor predicting cannabis use among youth is childhood emotional abuse (CEA), which has been associated with substance use behaviors more broadly. Although CEA may be associated with increased cannabis use in general, it is likely that sex may have an impact on these relations, given that girls are more likely to use substances following abuse experiences than boys. The purpose of the current study as to examine longitudinal relations between CEA and gender on cannabis use during adolescence...
March 2018: Translational Issues in Psychological Science
https://www.readbyqxmd.com/read/29930934/synthetic-and-non-synthetic-cannabinoid-drugs-and-their-adverse-effects-a-review-from-public-health-prospective
#4
REVIEW
Koby Cohen, Aviv M Weinstein
There is a growing use of novel psychoactive substances containing synthetic cannabinoids. Synthetic cannabinoid products have effects similar to those of natural cannabis, yet, these drugs are more potent and dangerous, and have been associated with dangerous adverse effects. Here, we review current literature on the epidemiology, acute, and chronic effects of synthetic and natural cannabinoid-based drugs. Synthetic drugs contain a mixture of psychoactive compounds that mostly bind cannabinoid receptors with high potency...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29929507/who-seeks-treatment-for-cannabis-use-registered-characteristics-and-physical-psychological-and-psychosocial-problem-indicators-among-cannabis-patients-and-matched-controls
#5
Solveig Glestad Christiansen, Anne Line Bretteville-Jensen
BACKGROUND: There has been an absolute and relative increase in the number of patients with cannabis-related disorders as the principal diagnosis in many countries in recent years. Cannabis is now the most frequently mentioned problem drug reported by new patients in Europe, and cannabis patients constituted one third of all drug treatment patients in 2015. There is limited knowledge with regard to patient characteristics, the extent and types of health and psychosocial problems, as well as their association with long-term outcomes...
June 22, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29929386/early-adolescent-substance-use-and-mental-health-problems-and-service-utilisation-in-a-school-based-sample
#6
Elizabeth Brownlie, Joseph H Beitchman, Gloria Chaim, David A Wolfe, Brian Rush, Joanna Henderson
OBJECTIVE: This paper reports on substance use, mental health problems, and mental health service utilisation in an early adolescent school-based sample. METHOD: Participants were 1,360 grade 7 and 8 students from 4 regions of Ontario, Canada. Students completed an in-class survey on mental health and substance use. The sampling strategy and survey items on demographics, substance use, service utilisation, and distress were adapted from the Ontario Student Drug Use and Health Survey...
January 1, 2018: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29928919/the-psychoactive-substance-of-cannabis-%C3%AE-9-tetrahydrocannabinol-thc-negatively-regulates-cftr-in-airway-cells
#7
Sheng-Wei Chang, Jack Wellmerling, Xiaoli Zhang, Rachael E Rayner, Wissam Osman, Sara Mertz, Amal O Amer, Mark E Peeples, Prosper N Boyaka, Estelle Cormet-Boyaka
BACKGROUND: Marijuana consumption is on the rise in the US but the health benefits of cannabis smoking are controversial and the impact of cannabis components on lung homeostasis is not well-understood. Lung function requires a fine regulation of the ion channel CFTR, which is responsible for fluid homeostasis and mucocilliary clearance. The goal of this study was to assess the effect that exposure to Δ9-tetrahydrocannabinol (THC), the psychoactive substance present in marijuana, has on CFTR expression and function...
June 18, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29928146/therapeutic-potential-of-medicinal-marijuana-an-educational-primer-for-health-care-professionals
#8
REVIEW
Yara Mouhamed, Andrey Vishnyakov, Bessi Qorri, Manpreet Sambi, Sm Signy Frank, Catherine Nowierski, Anmol Lamba, Umrao Bhatti, Myron R Szewczuk
With the proposed Canadian July 2018 legalization of marijuana through the Cannabis Act, a thorough critical analysis of the current trials on the efficacy of medicinal marijuana (MM) as a treatment option is necessary. This review is particularly important for primary care physicians whose patients may be interested in using MM as an alternative therapy. In response to increased interest in MM, Health Canada released a document in 2013 for general practitioners (GPs) as an educational tool on the efficacy of MM in treating some chronic and acute conditions...
2018: Drug, Healthcare and Patient Safety
https://www.readbyqxmd.com/read/29928123/addictive-potential-of-novel-treatments-for-refractory-depression-and-anxiety
#9
REVIEW
Dusan Kolar
Treatment-resistant mood disorders and anxiety disorders require intensive treatment, but treatment options should balance benefits and adverse effects or other potential detrimental effects on patients, including the risk of developing prescription medication addiction. Some of the newer treatment modalities for mood and anxiety disorders may have similar properties to benzodiazepines. The goal of this review was to identify the potential for developing dependence on the novel treatment approaches to treatment-resistant depression and refractory anxiety disorders...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29927691/a-survey-of-payer-perspectives-on-cannabis-use-disorder
#10
Andrew M Kiselica, Amy Duhig, Ivan Montoya, Phil Skolnick, Jennifer Floyd, Cigi Byars
BACKGROUND: Cannabis use disorder (CUD) as described/defined in DSM 5, is characterized by impaired control of marijuana use and related personal, health, and legal consequences. CUD is a serious public health problem, affecting nearly 6 million individuals in the United States. There are no FDA approved medications to treat this disorder. The lack of available treatment options contributes to uncertainties by drug sponsors about formulary and reimbursement decision-making for CUD pharmacotherapies...
June 21, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29927066/cannabis-use-as-a-risk-factor-for-psychotic-like-experiences-a-systematic-review-of-non-clinical-populations-evaluated-with-the-community-assessment-of-psychic-experiences
#11
REVIEW
Taciana C C Ragazzi, Rosana Shuhama, Paulo R Menezes, Cristina M Del-Ben
AIM: Epidemiological data have provided evidence that psychotic-like experiences (PLEs) can occur in the general population, not necessarily accompanied by the impairment and suffering observed in formal psychiatric diagnoses. According to the psychosis continuum hypothesis, PLEs would be subject to the same risk factors as frank psychosis. The aim of this review was to summarize observational studies that evaluated cannabis use as a risk factor for PLEs as determined by the Community Assessment of Psychic Experiences in non-clinical samples...
June 21, 2018: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29926471/the-challenges-of-medical-cannabis-and-mental-health-a-clinical-perspective
#12
REVIEW
Giles Newton-Howes
The use of cannabis as a medicine has a long tradition in western medicine. It has been seen as a viable option for the treatment of various neurological and psychiatric conditions, and recently there is again interest in the place of cannabinoids in the pharmacopoeia. What has become increasingly clear, however, is these benefits need to be weighed carefully against the potential difficulty associated with herbal cannabis and cannabinoid compounds for an individual's mental health. This challenges the use of cannabis as a medication and the regulation of its prescription...
June 20, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29923616/medicinal-cannabinoids-in-palliative-care
#13
REVIEW
M Agar
The treatment of symptoms in people with palliative diagnoses begins with meticulous clinical assessment with treatment choice (s) selected based on an understanding of the symptom aetiology and the evidence which underpins its treatment. Increasingly the merits of palliative care have been established earlier in the disease trajectory where treatment outcomes may include increased survival and maintenance of function. There is strong public support for the availability of medicinal cannabis, particularly for people with palliative diagnoses...
June 20, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29923025/cannabinoids-for-treatment-of-ms-symptoms-state-of-the-evidence
#14
REVIEW
Jessica Rice, Michelle Cameron
PURPOSE OF REVIEW: Cannabis and cannabinoids have been used medically and recreationally for thousands of years and recently there has been a growing body of research in this area. With increased access now that medical marijuana is available in many jurisdictions, patients and providers want to know more about the evidence for benefits and risks of cannabinoid use. This paper provides an overview of the available cannabinoid-based formulations, a summary of the highest quality evidence for the use of cannabinoids for treating spasticity and pain associated with multiple sclerosis (MS), and a discussion of possible dosing regimens based on information from these studies...
June 19, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29922897/is-there-an-effect-of-cannabis-consumption-on-acute-pancreatitis
#15
C Roberto Simons-Linares, Jodie A Barkin, Yuchen Wang, Palashkumar Jaiswal, William Trick, Michael J Bartel, Jamie S Barkin
BACKGROUND AND AIM: Twenty-percentage of acute pancreatitis (AP) cases is labeled as idiopathic. Cannabis remains the most frequently used illicit drug in the world. The aim of this study was to identify the prevalence of cannabis use among all patients with a first episode of AP, particularly in those labeled as idiopathic etiology, and determine any effect on AP severity. METHODS: Retrospective cohort of all consecutive patients admitted with a first episode of AP at a large tertiary referral hospital from 01/2013 through 12/2014...
June 20, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29921612/cannabis-cannabis-everywhere-uk-to-review-medical-cannabis-policy-as-canada-plans-imminent-legalisation-for-all-uses
#16
Richard Hurley
No abstract text is available yet for this article.
June 19, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29920542/prevalence-of-drug-use-among-drivers-based-on-mandatory-random-tests-in-a-roadside-survey
#17
Manuela Alcañiz, Montserrat Guillen, Miguel Santolino
BACKGROUND: In the context of road safety, this study aims to examine the prevalence of drug use in a random sample of drivers. METHODS: A stratified probabilistic sample was designed to represent vehicles circulating on non-urban roads. Random drug tests were performed during autumn 2014 on 521 drivers in Catalonia (Spain). Participation was mandatory. The prevalence of drug driving for cannabis, methamphetamines, amphetamines, cocaine, opiates and benzodiazepines was assessed...
2018: PloS One
https://www.readbyqxmd.com/read/29914541/family-management-risk-and-protective-factors-for-adolescent-substance-use-in-south-africa
#18
Beatrice Wamuyu Muchiri, Monika M L Dos Santos
BACKGROUND: An increasingly recognised prevention approach for substance use entails a reduction in risk factors, and the enhancement of promotive, or protective factors in individuals and the environment surrounding them during their growth and development. METHODS: This exploratory study evaluated the effect of potential risk and protective factors associated with family management relating to adolescent substance use in South Africa. Exploratory analysis and cumulative odds ordinal logistic regression modelling was performed on the data, while controlling for the influence of demographic and socio-economic characteristics on adolescent substance use...
June 19, 2018: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/29914409/adverse-childhood-experiences-among-patients-with-substance-use-disorders-at-a-referral-psychiatric-hospital-in-kenya
#19
Sarah Kanana Kiburi, Keneilwe Molebatsi, Anne Obondo, Mary W Kuria
BACKGROUND: Substance use disorders are a major cause of health and social problems worldwide. Research evidence shows a strong graded relationship of adverse childhood experiences and substance use in adulthood. This study aimed at determining the prevalence of adverse childhood experiences and their association with substance use among patients with substance use disorders. METHOD: The study used a descriptive cross-sectional design. A total of 134 patients aged 18 years and above receiving inpatient treatment for substance use disorders were recruited into the study...
June 18, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29911410/endophytes-of-industrial-hemp-cannabis-sativa-l-cultivars-identification-of-culturable-bacteria-and-fungi-in-leaves-petioles-and-seeds
#20
Maryanne Scott, Mamta Rani, Jamil Samsatly, Jean-Benoit Charron, Suha Jabaji
Plant endophytes are a group of microorganisms that reside asymptomatically within the healthy living tissue. The diversity and molecular and biochemical characterization of industrial hemp-associated endophytes have not been previously studied. This study explored the abundance and diversity of culturable endophytes residing in petioles, leaves, and seeds of three industrial hemp cultivars, and examined their biochemical attributes and antifungal potential. A total of 134 bacterial and 53 fungal strains were isolated from cultivars Anka, CRS-1, and Yvonne...
June 18, 2018: Canadian Journal of Microbiology
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