keyword
MENU ▼
Read by QxMD icon Read
search

stimuli responsive materials

keyword
https://www.readbyqxmd.com/read/28534049/bio-inspired-metal-coordinate-hydrogels-with-programmable-viscoelastic-material-functions-controlled-by-longwave-uv-light
#1
Scott C Grindy, Niels Holten-Andersen
Control over the viscoelastic mechanical properties of hydrogels intended for use as biomedical materials has long been a goal of soft matter scientists. Recent research has shown that materials made from polymers with reversibly associating transient crosslinks are a promising strategy for controlling viscoelasticity in hydrogels, for example leading to systems with precisely tunable mechanical energy-dissipation. We and others have shown that bio-inspired histidine:transition metal ion complexes allow highly precise and tunable control over the viscoelastic properties of transient network hydrogels...
May 23, 2017: Soft Matter
https://www.readbyqxmd.com/read/28533376/b12-dependent-photoresponsive-protein-hydrogels-for-controlled-stem-cell-protein-release
#2
Ri Wang, Zhongguang Yang, Jiren Luo, I-Ming Hsing, Fei Sun
Thanks to the precise control over their structural and functional properties, genetically engineered protein-based hydrogels have emerged as a promising candidate for biomedical applications. Given the growing demand for creating stimuli-responsive "smart" hydrogels, here we show the synthesis of entirely protein-based photoresponsive hydrogels by covalently polymerizing the adenosylcobalamin (AdoB12)-dependent photoreceptor C-terminal adenosylcobalamin binding domain (CarHC) proteins using genetically encoded SpyTag-SpyCatcher chemistry under mild physiological conditions...
May 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28532032/agar-gelatin-bilayer-gel-matrix-fabricated-by-simple-thermo-responsive-sol-gel-transition-method
#3
Yifeng Wang, Meng Dong, Mengmeng Guo, Xia Wang, Jing Zhou, Jian Lei, Chuanhang Guo, Chaoran Qin
We present a simple and environmentally-friendly method to generate an agar/gelatin bilayer gel matrix for further biomedical applications. In this method, the thermally responsive sol-gel transitions of agar and gelatin combined with the different transition temperatures are exquisitely employed to fabricate the agar/gelatin bilayer gel matrix and achieve separate loading for various materials (e.g., drugs, fluorescent materials, and nanoparticles). Importantly, the resulting bilayer gel matrix provides two different biopolymer environments (a polysaccharide environment vs a protein environment) with a well-defined border, which allows the loaded materials in different layers to retain their original properties (e...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28528553/protonation-induced-room-temperature-phosphorescence-in-fluorescent-polyurethane
#4
Wei Sun, Zhaowu Wang, Tao Wang, Li Yang, Jun Jiang, Xing Yuan Zhang, Yi Luo, Guoqing Zhang
Room-temperature phosphorescence (RTP) from purely organic systems is of practical importance in biological imaging, oxygen sensing and displaying technologies. The key step to obtaining RTP from organic molecules is efficient intersystem crossing (ISC), which is usually low compared to inorganic materials. Here we show that protonation of a dye molecule, a thioflavin derivative, in strongly polar polyurethane can be used to effectively harness RTP. Prior to protonation, the predominant transition is π-π* for the polymer, which has nearly undetectable RTP due to the large singlet-triplet energy splitting (0...
May 22, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28522885/dynamically-tunable-cell-culture-platforms-for-tissue-engineering-and-mechanobiology
#5
Koichiro Uto, Jonathan H Tsui, Cole A DeForest, Deok-Ho Kim
Human tissues are sophisticated ensembles of many distinct cell types embedded in the complex, but well-defined, structures of the extracellular matrix (ECM). Dynamic biochemical, physicochemical, and mechano-structural changes in the ECM define and regulate tissue-specific cell behaviors. To recapitulate this complex environment in vitro, dynamic polymer-based biomaterials have emerged as powerful tools to probe and direct active changes in cell function. The rapid evolution of polymerization chemistries, structural modulation, and processing technologies, as well as the incorporation of stimuli-responsiveness, now permit synthetic microenvironments to capture much of the dynamic complexity of native tissue...
February 2017: Progress in Polymer Science
https://www.readbyqxmd.com/read/28522531/bragg-coherent-diffractive-imaging-of-single-grain-defect-dynamics-in-polycrystalline-films
#6
Allison Yau, Wonsuk Cha, Matthew W Kanan, G Brian Stephenson, Andrew Ulvestad
Polycrystalline material properties depend on the distribution and interactions of their crystalline grains. In particular, grain boundaries and defects are crucial in determining their response to external stimuli. A long-standing challenge is thus to observe individual grains, defects, and strain dynamics inside functional materials. Here we report a technique capable of revealing grain heterogeneity, including strain fields and individual dislocations, that can be used under operando conditions in reactive environments: grain Bragg coherent diffractive imaging (gBCDI)...
May 19, 2017: Science
https://www.readbyqxmd.com/read/28516168/selective-surface-pegylation-of-uio-66-nanoparticles-for-enhanced-stability-cell-uptake-and-ph-responsive-drug-delivery
#7
Isabel Abánades Lázaro, Salame Haddad, Sabrina Sacca, Claudia Orellana-Tavra, David Fairen-Jimenez, Ross S Forgan
The high storage capacities and excellent biocompatibilities of metal-organic frameworks (MOFs) have made them emerging candidates as drug-delivery vectors. Incorporation of surface functionality is a route to enhanced properties, and here we report on a surface-modification procedure-click modulation-that controls their size and surface chemistry. The zirconium terephthalate MOF UiO-66 is (1) synthesized as ∼200 nm nanoparticles coated with functionalized modulators, (2) loaded with cargo, and (3) covalently surface modified with poly(ethylene glycol) (PEG) chains through mild bioconjugate reactions...
April 13, 2017: Chem
https://www.readbyqxmd.com/read/28513664/a-resilient-and-luminescent-stimuli-responsive-hydrogel-from-a-heterotopic-1-8-naphthalimide-derived-ligand
#8
Chris S Hawes, Amy D Lynes, Kevin Byrne, Wolfgang Schmitt, Gavin Ryan, Matthias E Möbius, Thorfinnur Gunnlaugsson
A heterotopic naphthalimide ligand N-(4-picolyl)-4-(4'-carboxyphenoxy)-1,8-naphthalimide HL is utilised for the formation of self-assembled soft materials. In the presence of K(+) ions, L(-) forms a robust photoluminescent hydrogel 1 which is reversible under thermal, mechanical or chemical stimuli.
May 17, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28509539/tunable-luminescent-lanthanide-supramolecular-assembly-based-on-photoreaction-of-anthracene
#9
Yan Zhou, Heng-Yi Zhang, Zhi-Yuan Zhang, Yu Liu
Lanthanide luminescence materials generally show great superiority in light-emitting materials, gaining increasingly exploration in the design of advanced functional materials. Herein, we prepared a supramolecular assembly via the coordination of a host molecule (1) and dilanthanide metal. Compound 1 possesses a 9,10-diphenylanthracene (ant) core with photo-sensitivity and terminal terpyridine (tpy), containing two-arm dibenzo-24-crown-8. The assembly could exhibit excellent lanthanide luminescence after un-dergoing a photoreaction from anthracene unit in 1...
May 16, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28508633/ionic-complexes-of-metal-oxide-clusters-for-versatile-self-assemblies
#10
Bao Li, Wen Li, Haolong Li, Lixin Wu
The combination of rational design of building components and suitable utilization of driving force affords spontaneous molecular assemblies with well-defined nanostructure and morphology over multiple length scales. The serious challenges in constructing assemblies with structural advantages for the realization of functions programmed into the building components usually lie ahead since the process that occurs does not always follow the expected roadmap in the absence of external intervention. Thus, prefabricated intermediates that help in governing the target self-assemblies are developed into a type of unique building blocks...
May 16, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28503664/fixing-the-stimulus-as-fixed-effect-fallacy-in-task-fmri
#11
Jacob Westfall, Thomas E Nichols, Tal Yarkoni
Most functional magnetic resonance imaging (fMRI) experiments record the brain's responses to samples of stimulus materials (e.g., faces or words). Yet the statistical modeling approaches used in fMRI research universally fail to model stimulus variability in a manner that affords population generalization, meaning that researchers' conclusions technically apply only to the precise stimuli used in each study, and cannot be generalized to new stimuli. A direct consequence of this stimulus-as-fixed-effect fallacy is that the majority of published fMRI studies have likely overstated the strength of the statistical evidence they report...
December 9, 2016: Wellcome Open Research
https://www.readbyqxmd.com/read/28499634/a-degradable-poly-vinyl-alcohol-iron-oxide-nanoparticle-hydrogel
#12
Dawn Bannerman, Xinyi Li, Wankei Wan
Polymeric materials that contain magnetic nanoparticles are extremely useful in many applications including as multifunctional drug carriers, imaging contrast agents, or scaffold material. There is a need for biomaterials with appropriate chemical, mechanical, and magnetic properties that also have the ability to degrade or dissolve over time so they can be eliminated from the body following use. In this work, we explore the use of iron oxide nanoparticle (IONP) formation in poly(vinyl alcohol) (PVA) as a crosslinking method in conjunction with physical crosslinking achieved using low temperature thermal cycling (LTTC)...
May 9, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28499602/from-polyelectrolyte-complexes-to-polyelectrolyte-multilayers-electrostatic-assembly-nanostructure-dynamics-and-functional-properties
#13
Biswa P Das, Marina Tsianou
Polyelectrolyte complexes (PECs) are three-dimensional macromolecular structures formed by association of oppositely charged polyelectrolytes in solution. Polyelectrolyte multilayers (PEMs) can be considered a special case of PECs prepared by layer-by-layer (LbL) assembly that involves sequential deposition of molecular-thick polyelectrolyte layers with nanoscale control over the size, shape, composition and internal organization. Although many functional PEMs with novel physical and chemical characteristics have been developed, the current practical applications of PEMs are limited to those that require only a few bilayers and are relatively easy to prepare...
December 16, 2016: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28497535/stimuli-responsive-polymeric-nanoparticles
#14
REVIEW
Xiaolin Liu, Ying Yang, Marek W Urban
There is increasing evidence that stimuli-responsive nanomaterials have become significantly critical components of modern materials design and technological developments. Recent advances in synthesis and fabrication of stimuli-responsive polymeric nanoparticles with built-in stimuli-responsive components (Part A) and surface modifications of functional nanoparticles that facilitate responsiveness (Part B) are outlined here. The synthesis and construction of stimuli-responsive spherical, core-shell, concentric, hollow, Janus, gibbous/inverse gibbous, and cocklebur morphologies are discussed in Part A, with the focus on shape, color, or size changes resulting from external stimuli...
May 12, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28496523/probing-the-causes-of-thermal-hysteresis-using-tunable-nagg-micelles-with-linear-and-brush-like-thermoresponsive-coronas
#15
L D Blackman, M I Gibson, R K O'Reilly
Self-assembled thermoresponsive polymers in aqueous solution have great potential as smart, switchable materials for use in biomedical applications. In recent years, attention has turned to the reversibility of these polymers' thermal transitions, which has led to debate over what factors influence discrepancies in the transition temperature when heating the system compared to the temperature obtained when cooling the system, known as the thermal hysteresis. Herein, we synthesize micelles with tunable aggregation numbers (Nagg) whose cores contain poly(n-butyl acrylate-co-N,N-dimethylacrylamide) (p(nBA-co-DMA)) and four different thermoresponsive corona blocks, namely poly(N-isopropylacrylamide) (pNIPAM), poly(N,N-diethylacrylamide) (pDEAm), poly(diethylene glycol monomethyl ether methacrylate) (pDEGMA) and poly(oligo(ethylene glycol) monomethyl ether methacrylate) (pOEGMA)...
January 1, 2017: Polymer Chemistry
https://www.readbyqxmd.com/read/28493712/stimulus-responsive-degradable-polylactide-based-block-copolymer-nanoassemblies-for-controlled-enhanced-drug-delivery
#16
Kamaljeet K Bawa, Jung Kwon Oh
Polylactide (PLA) is biocompatible and FDA-approved for clinical use and thus has been a choice of the materials valuable for extensive applications in biomedical fields. However, conventionally designed PLA-based amphiphilic block copolymer (ABP) nanoassemblies exhibit slow and uncontrolled release of encapsulated drugs because of the slow biodegradation of hydrophobic PLA in physiological conditions. To improve potentials for clinical use and commercialization of conventional PLA-based nanoassemblies, stimulus-responsive degradation (SRD) platform has been introduced into the design of PLA-based nanoassemblies for enhanced/controlled release of encapsulated drugs...
May 23, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28478676/stimuli-responsive-bubbles-and-foams-stabilized-with-solid-particles
#17
Syuji Fujii, Yoshinobu Nakamura
Particle-stabilized bubbles and foams have been observed and used in a wide range of industrial sectors and have been exploited as a technology platform for the production of advanced functional materials. The stability, structure, shape, and movement of these bubbles and foams can be controlled by external stimuli such as the pH, temperature, magnetic fields, ultrasonication, mechanical stress, surfactants, and organic solvents. Stimuli-responsive modes can be categorized into three classes: (i) bubbles/foams whose stability can be controlled by the adsorption/desorption/dissolution of solid particles to/from/at gas-liquid interfaces, (ii) bubbles/foams that can move, and (iii) bubbles/foams that can change their shapes and structures...
May 11, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28475310/novel-light-responsive-biocompatible-hydrogels-produced-by-initiated-chemical-vapor-deposition
#18
Katrin Unger, Paul Salzmann, Cecilia Masciullo, Marco Cecchini, Georg Koller, Anna Maria Coclite
A novel multiresponsive hydrogel has been synthesized by initiated chemical vapor deposition (iCVD). Hydrogels are known for their dynamic swelling response to aqueous environments. A chemical functionalization of the hydrogel surface was performed to add other stimuli-responsive functionalities and obtain a smart material that responds to two stimuli: light irradiation and exposure to aqueous environment. Modifying the hydrogel surface with solution-based methods is often problematic because of the damages caused by the permeation of solvents in the hydrogel...
May 12, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28474746/light-responsive-hierarchically-structured-liquid-crystal-polymer-networks-for-harnessing-cell-adhesion-and-migration
#19
Gülistan Koçer, Jeroen Ter Schiphorst, Matthew Hendrikx, Hailu G Kassa, Philippe Leclère, Albertus P H J Schenning, Pascal Jonkheijm
Extracellular microenvironment is highly dynamic where spatiotemporal regulation of cell-instructive cues such as matrix topography tightly regulates cellular behavior. Recapitulating dynamic changes in stimuli-responsive materials has become an important strategy in regenerative medicine to generate biomaterials which closely mimic the natural microenvironment. Here, light responsive liquid crystal polymer networks are used for their adaptive and programmable nature to form hybrid surfaces presenting micrometer scale topographical cues and changes in nanoscale roughness at the same time to direct cell migration...
May 5, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28473884/characterisation-of-adipocyte-derived-extracellular-vesicle-subtypes-identifies-distinct-protein-and-lipid-signatures-for-large-and-small-extracellular-vesicles
#20
Maëva Durcin, Audrey Fleury, Emiliane Taillebois, Grégory Hilairet, Zuzana Krupova, Céline Henry, Sandrine Truchet, Martin Trötzmüller, Harald Köfeler, Guillaume Mabilleau, Olivier Hue, Ramaroson Andriantsitohaina, Patrice Martin, Soazig Le Lay
Extracellular vesicles (EVs) are biological vectors that can modulate the metabolism of target cells by conveying signalling proteins and genomic material. The level of EVs in plasma is significantly increased in cardiometabolic diseases associated with obesity, suggesting their possible participation in the development of metabolic dysfunction. With regard to the poor definition of adipocyte-derived EVs, the purpose of this study was to characterise both qualitatively and quantitatively EVs subpopulations secreted by fat cells...
2017: Journal of Extracellular Vesicles
keyword
keyword
41558
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"