keyword
MENU ▼
Read by QxMD icon Read
search

Mobile Applications

keyword
https://www.readbyqxmd.com/read/28918324/simultaneous-determination-and-pharmacokinetic-study-of-twelve-bioactive-compounds-in-rat-plasma-after-intravenous-administration-of-xuebijing-injection-by-uhplc-q-orbitrap-hrms
#1
Lihua Zuo, Qiuyue Zhong, Zhenhui Wang, Zhi Sun, Lin Zhou, Zhuolun Li, Tanye Xu, Yingying Shi, Jinfa Tang, Shuzhang Du, Xiaojian Zhang
Xuebijing injection (XBJ) is a traditional Chinese herbal prescription widely used in the treatment of sepsis. Extensive studies revealed that the major bioactive constituents of XBJ injection, including phenolic acids, flavonoids, monoterpene glycosides, lactones and organic acids, play an important role in the treatment. In this study, a rapid, sensitive and accurate ultra high performance liquid chromatography - Q Exactive hybrid quadrupole - orbitrap high-resolution accurate mass spectrometry (UHPLC-Q-Orbitrap HRMS) method was developed for simultaneous determination of twelve bioactive compounds in rat plasma after intravenous administration of XBJ injection...
September 8, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28918323/quantitative-determination-of-carfilzomib-in-mouse-plasma-by-liquid-chromatography-tandem-mass-spectrometry-and-its-application-to-a-pharmacokinetic-study
#2
Jee Sun Min, Jiseon Kim, Jung Ho Kim, Doyun Kim, Yu Fen Zheng, Ji Eun Park, Wooin Lee, Soo Kyung Bae
A highly sensitive and rapid LC-MS/MS method was developed and validated to determine the levels of carfilzomib in mice plasma by using chlorpropamide as an internal standard. Carfilzomib and chlorpropamide were extracted from 5 μL of plasma after protein precipitation with acetonitrile. Chromatographic separation was performed on Phenomenex Luna C18 column (50×2.0mm id, 3μm). The mobile phase consisted of 0.1% formic acid in acetonitrile -0.1% formic acid in water (1:1v/v) and the flow rate was 0.3mL/min...
September 1, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28917757/innovative-thin-layer-chromatographic-method-combined-with-fluorescence-detection-for-specific-determination-of-febuxostat-application-in-biological-fluids
#3
Abdel-Maaboud I Mohamed, Mahmoud A Omar, Sayed M Derayea, Mohamed A Hammad, Abobakr A Mohamed
A newly developed thin-layer chromatographic (TLC) method coupled with fluorescence detection for specific determination of Febuxostat (FEB) was designed. The proposed method adopts exposure of FEB on a developed TLC plate to hydrochloric acid vapors, resulting in a large enhancement of its weak fluorescence, permitting its specific and sensitive determination in real human plasma and urine after excitation at 345nm on 60 F254 silica gel plates using toluene-ethyl acetate-methanol-glacial acetic acid; (30:10:5:0...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917748/selectivity-improvement-of-positive-photoionization-ion-mobility-spectrometry-for-rapid-detection-of-organophosphorus-pesticides-by-switching-dopant-concentration
#4
Qinghua Zhou, Jia Li, Bin Wang, Shuang Wang, Haiyang Li, Jinyuan Chen
Ion mobility spectrometry (IMS) opened a potential avenue for the rapid detection of organophosphorus pesticides (OPPs), though an improved selectivity of stand-alone IMS was still in high demand. In this study, a stand-alone positive photoionization ion mobility spectrometry (PP-IMS) apparatus was constructed for the rapid detection of OPPs with acetone as dopant. The photoionization of acetone molecules was induced by the ultraviolet irradiation to produce the reactant ions (Ac)2H(+), which were employed to ionize the OPPs including fenthion, imidan, phosphamidon, dursban, dimethoate and isocarbophos via the proton transfer reaction...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917733/stabilization-of-gas-phase-uranyl-complexes-enables-rapid-speciation-using-electrospray-ionization-and-ion-mobility-mass-spectrometry
#5
Austen L Davis, Brian H Clowers
Significant challenges exist when characterizing f-element complexes in solution using traditional approaches such as electrochemical and spectroscopic techniques as they do not always capture information for lower abundance species. However, provided a metal-complex with sufficient stability, soft ionization techniques such as electrospray offer a means to quantify and probe the characteristics of such systems using mass spectrometry. Unfortunately, the gas-phase species observed in ESI-MS systems do not always reflect the solution phase distributions due to the inherent electrochemical mechanism of the electrospray process, ion transfer from ambient to low pressures conditions, and other factors that are related to droplet evaporation...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917183/visualisation-of-an-nspef-induced-calcium-wave-using-the-genetically-encoded-calcium-indicator-gcamp-in-u87-human-glioblastoma-cells
#6
Lynn Carr, Sylvia M Bardet, Delia Arnaud-Cormos, Philippe Leveque, Rodney P O'Connor
Cytosolic, synthetic chemical calcium indicators are typically used to visualise the rapid increase in intracellular calcium ion concentration that follows nanosecond pulsed electric field (nsPEF) application. This study looks at the application of genetically encoded calcium indicators (GECIs) to investigate the spatiotemporal nature of nsPEF-induced calcium signals using fluorescent live cell imaging. Calcium responses to 44kV/cm, 10ns pulses were observed in U87-MG cells expressing either a plasma membrane targeted GECI (GCaMP5-G), or one cytosolically expressed (GCaMP6-S), and compared to the response of cells loaded with cytosolic or plasma membrane targeted chemical calcium indicators...
September 8, 2017: Bioelectrochemistry
https://www.readbyqxmd.com/read/28916207/mobile-application-reminders-slightly-reduce-plaque-and-gingival-index-in-patients-undergoing-orthodontic-treatment-with-fixed-appliances
#7
Romina Brignardello-Petersen
No abstract text is available yet for this article.
September 9, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28915825/effect-of-a-mobile-app-intervention-on-vegetable-consumption-in-overweight-adults-a-randomized-controlled-trial
#8
Sarah Mummah, Thomas N Robinson, Maya Mathur, Sarah Farzinkhou, Stephen Sutton, Christopher D Gardner
BACKGROUND: Mobile applications (apps) have been heralded as transformative tools to deliver behavioral health interventions at scale, but few have been tested in rigorous randomized controlled trials. We tested the effect of a mobile app to increase vegetable consumption among overweight adults attempting weight loss maintenance. METHODS: Overweight adults (n=135) aged 18-50 years with BMI=28-40 kg/m(2) near Stanford, CA were recruited from an ongoing 12-month weight loss trial (parent trial) and randomly assigned to either the stand-alone, theory-based Vegethon mobile app (enabling goal setting, self-monitoring, and feedback and using "process motivators" including fun, surprise, choice, control, social comparison, and competition) or a wait-listed control condition...
September 15, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28914823/hole-transporting-materials-for-printable-perovskite-solar-cells
#9
REVIEW
Paola Vivo, Jagadish K Salunke, Arri Priimagi
Perovskite solar cells (PSCs) represent undoubtedly the most significant breakthrough in photovoltaic technology since the 1970s, with an increase in their power conversion efficiency from less than 5% to over 22% in just a few years. Hole-transporting materials (HTMs) are an essential building block of PSC architectures. Currently, 2,2',7,7'-tetrakis-(N,N'-di-p-methoxyphenylamine)-9,9'-spirobifluorene), better known as spiro-OMeTAD, is the most widely-used HTM to obtain high-efficiency devices. However, it is a tremendously expensive material with mediocre hole carrier mobility...
September 15, 2017: Materials
https://www.readbyqxmd.com/read/28914540/adhesion-and-separation-of-nanoparticles-on-polymer-grafted-porous-substrates
#10
Kolattukudy P Santo, Aleksey Vishnyakov, Yefim Brun, Alexander V Neimark
This work explores interactions of functionalized nanoparticles (NP) with polymer brushes (PB) in a binary mixture of good and poor solvents. NP-PB systems are used in multiple applications, and we are particularly interested in the problem of chromatographic separation of NPs on polymer-grafted porous columns. This process involves NP flow through the pore channels with walls covered by PBs. NP-PB adhesion is governed by adsorption of polymer chains to NP surface and entropic repulsion caused by the polymer chain confinement between NP and the channel wall...
September 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28914084/lc-ms-determination-of-fentanyl-in-human-serum-and-application-to-a-fentanyl-transdermal-delivery-pharmacokinetic-study
#11
Mingming Yu, Inas A Abdallah, Soo Hyeon Shin, Dana C Hammell, Audra L Stinchcomb, Hazem E Hassan
AIM: Fentanyl is an opioid agonist used for acute and chronic pain management. In this report, a highly sensitive and simple LC-MS/MS method using Hydrophilic Interaction Chromatography (HILIC) column was validated and used for fentanyl quantification in human serum. RESULTS: The isocratic mobile phase was composed of acetonitrile: 10 mM ammonium formate buffer (pH = 3.2; 90:10, v/v). The assay was linear over a concentration range of 10-10,000 pg/ml. The accuracy of the validation method ranged from 93...
September 15, 2017: Bioanalysis
https://www.readbyqxmd.com/read/28914061/mobile-applications-as-good-intervention-tools-for-individuals-with-depression
#12
Petra Marešová, Blanka Klímová, Kamil Kuča
At present mental disorders affect approximately 450 million people around the world. Depressive disorder is probably one of the most serious disorders and as a type of chronic disease, it represents a global threat and burdens economic and social systems of both individuals and governments worldwide. One of these most recent non-pharmacological approaches is also the so-called mHealth (mobile health), the use of mobile devices for the practice of medicine and public health, which proves to be effective particularly in the early stages of depression...
2017: Ceská a Slovenská Farmacie
https://www.readbyqxmd.com/read/28913428/rubbery-electronics-and-sensors-from-intrinsically-stretchable-elastomeric-composites-of-semiconductors-and-conductors
#13
Hae-Jin Kim, Kyoseung Sim, Anish Thukral, Cunjiang Yu
A general strategy to impart mechanical stretchability to stretchable electronics involves engineering materials into special architectures to accommodate or eliminate the mechanical strain in nonstretchable electronic materials while stretched. We introduce an all solution-processed type of electronics and sensors that are rubbery and intrinsically stretchable as an outcome from all the elastomeric materials in percolated composite formats with P3HT-NFs [poly(3-hexylthiophene-2,5-diyl) nanofibrils] and AuNP-AgNW (Au nanoparticles with conformally coated silver nanowires) in PDMS (polydimethylsiloxane)...
September 2017: Science Advances
https://www.readbyqxmd.com/read/28912632/the-intra-rater-reliability-of-a-revised-3-point-grading-system-for-accessory-joint-mobilizations
#14
Jennifer Ward, Clair Hebron, Nicola J Petty
OBJECTIVES: Joint mobilizations are often quantified using a 4-point grading system based on the physiotherapist's detection of resistance. It is suggested that the initial resistance to joint mobilizations is imperceptible to physiotherapists, but that at some point through range becomes perceptible, a point termed R1. Grades of mobilization traditionally hinge around this concept and are performed either before or after R1. Physiotherapists, however, show poor reliability in applying grades of mobilization...
September 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28912113/mobile-augmented-reality-as-a-feature-for-self-oriented-blended-learning-in-medicine-randomized-controlled-trial
#15
Christoph Noll, Ute von Jan, Ulrike Raap, Urs-Vito Albrecht
BACKGROUND: Advantages of mobile Augmented Reality (mAR) application-based learning versus textbook-based learning were already shown in a previous study. However, it was unclear whether the augmented reality (AR) component was responsible for the success of the self-developed app or whether this was attributable to the novelty of using mobile technology for learning. OBJECTIVE: The study's aim was to test the hypothesis whether there is no difference in learning success between learners who employed the mobile AR component and those who learned without it to determine possible effects of mAR...
September 14, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28911738/effects-of-introducing-theanine-or-glutamic-acid-core-to-tralopyril-on-systemicity-and-insecticidal-activity
#16
Wen Yang, Yao Chen, Ying Zhang, Xiu-Bing Gao, Yu-Feng Zhou
Tralopyril was the active agent of a pro-insecticide chlorfenapyr. To simultaneously solve the problems of the phytotoxicity and non-systemic insecticidal activity of tralopyril, four new tralopyril conjugates containing theanine or glutamic acid moieties were designed and synthesized. Their phytotoxicity to tea shoot, phloem systemicity, and insecticidal activity were evaluated. Phytotoxic symptoms were not observed after the tea shoots were exposed to the four conjugates at concentrations of 2mM. The phloem mobility test on Ricinus communis L...
September 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/28911626/high-throughput-liquid-chromatography-tandem-mass-spectrometry-method-for-simultaneous-determination-of-fampridine-paroxetine-and-quinidine-in-rat-plasma-application-to-in%C3%A2-vivo-perfusion-study
#17
Suneetha Achanti, Raja Rajeswari Katta
A selective and high-throughput liquid chromatography-mass spectrometry method has been developed and validated for the simultaneous quantification of paroxetine, fampridine, and quinidine in rat plasma using imipramine as an internal standard. Following protein precipitation extraction, the analytes and internal standard were run on XBridge C18 column (150 mm × 4.6 mm, 5 μm) using a gradient mobile phase consisting of 5mM ammonium formate in water (pH 9.0) and acetonitrile in a flow gradience program...
October 2016: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28910505/a-review-on-organic-inorganic-halide-perovskite-photodetectors-device-engineering-and-fundamental-physics
#18
REVIEW
Mahshid Ahmadi, Ting Wu, Bin Hu
The last eight years (2009-2017) have seen an explosive growth of interest in organic-inorganic halide perovskites in the research communities of photovoltaics and light-emitting diodes. In addition, recent advancements have demonstrated that this type of perovskite has a great potential in the technology of light-signal detection with a comparable performance to commercially available crystalline Si and III-V photodetectors. The contemporary growth of state-of-the-art multifunctional perovskites in the field of light-signal detection has benefited from its outstanding intrinsic optoelectronic properties, including photoinduced polarization, high drift mobilities, and effective charge collection, which are excellent for this application...
September 14, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28910313/a-detailed-comparison-of-analysis-processes-for-mcc-ims-data-in-disease-classification-automated-methods-can-replace-manual-peak-annotations
#19
Salome Horsch, Dominik Kopczynski, Elias Kuthe, Jörg Ingo Baumbach, Sven Rahmann, Jörg Rahnenführer
MOTIVATION: Disease classification from molecular measurements typically requires an analysis pipeline from raw noisy measurements to final classification results. Multi capillary column-ion mobility spectrometry (MCC-IMS) is a promising technology for the detection of volatile organic compounds in the air of exhaled breath. From raw measurements, the peak regions representing the compounds have to be identified, quantified, and clustered across different experiments. Currently, several steps of this analysis process require manual intervention of human experts...
2017: PloS One
https://www.readbyqxmd.com/read/28910102/effects-of-charge-state-charge-distribution-and-structure-on-the-ion-mobility-of-protein-ions-in-helium-gas-results-from-trajectory-method-calculations
#20
Kenneth J Laszlo, Matthew F Bush
Collision cross section (Ω) values of gas-phase ions of proteins and protein complexes are used to probe the structures of the corresponding species in solution. Ions of many proteins exhibit increasing Ω values with increasing charge state, but most Ω values calculated for protein ions have used simple collision models that do not explicitly account for charge. Here we use a combination of ion mobility mass spectrometry experiments using helium gas and trajectory method calculations to characterize the extents to which increases in experimental Ω values with increasing charge state may be attributed to increased momentum transfer concomitant with enhanced long-range interactions between the protein ion and helium atoms...
September 14, 2017: Journal of Physical Chemistry. A
keyword
keyword
41522
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"